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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXB4_LHX9

Z-value: 0.84

Motif logo

Transcription factors associated with HOXB4_LHX9

Gene Symbol Gene ID Gene Info
ENSG00000182742.6 HOXB4
ENSG00000143355.16 LHX9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX9hg38_v1_chr1_+_197912462_1979125050.496.6e-03Click!
HOXB4hg38_v1_chr17_-_48578341_485783560.393.2e-02Click!

Activity profile of HOXB4_LHX9 motif

Sorted Z-values of HOXB4_LHX9 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB4_LHX9

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_+_72577939 4.48 ENST00000645773.1
transmembrane channel like 1
chr10_-_104085847 3.97 ENST00000648076.2
collagen type XVII alpha 1 chain
chr2_+_102337148 3.59 ENST00000311734.6
ENST00000409584.5
interleukin 1 receptor like 1
chr11_-_107858777 3.29 ENST00000525815.6
solute carrier family 35 member F2
chr12_-_10826358 3.05 ENST00000240619.2
taste 2 receptor member 10
chr2_-_160200289 2.97 ENST00000409872.1
integrin subunit beta 6
chr9_+_122371036 2.72 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chr9_+_72577369 2.68 ENST00000651183.1
transmembrane channel like 1
chr2_-_160200251 2.62 ENST00000428609.6
ENST00000409967.6
ENST00000283249.7
integrin subunit beta 6
chr17_+_59155726 2.58 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
proline rich 11
chr2_-_160200310 2.37 ENST00000620391.4
integrin subunit beta 6
chr8_-_124565699 2.29 ENST00000519168.5
MTSS I-BAR domain containing 1
chr6_+_130018565 2.29 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr11_+_33039996 2.25 ENST00000432887.5
ENST00000528898.1
ENST00000531632.6
t-complex 11 like 1
chrX_+_43656289 2.23 ENST00000338702.4
monoamine oxidase A
chr4_-_39032343 2.17 ENST00000381938.4
transmembrane protein 156
chr2_+_90038848 2.05 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr7_+_134843884 2.05 ENST00000445569.6
caldesmon 1
chr18_+_31447732 1.91 ENST00000257189.5
desmoglein 3
chr12_+_119668109 1.76 ENST00000229328.10
ENST00000630317.1
protein kinase AMP-activated non-catalytic subunit beta 1
chr9_+_122371014 1.74 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chr2_+_90172802 1.70 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr5_-_140346596 1.69 ENST00000230990.7
heparin binding EGF like growth factor
chr11_-_122116215 1.64 ENST00000560104.2
BH3-like motif containing, cell death inducer
chr14_-_67412112 1.64 ENST00000216446.9
pleckstrin 2
chr5_-_126595237 1.58 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr12_-_9869345 1.52 ENST00000228438.3
C-type lectin domain family 2 member B
chr21_-_26843012 1.47 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr4_-_159035226 1.45 ENST00000434826.3
chromosome 4 open reading frame 45
chr2_+_101839815 1.38 ENST00000421882.5
mitogen-activated protein kinase kinase kinase kinase 4
chr9_-_74952904 1.37 ENST00000376854.6
chromosome 9 open reading frame 40
chr9_+_72577788 1.37 ENST00000645208.2
transmembrane channel like 1
chr21_-_26843063 1.37 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr4_+_85604146 1.32 ENST00000512201.5
Rho GTPase activating protein 24
chr15_+_21579912 1.30 ENST00000628444.1
long intergenic non-protein coding RNA 2203
chr14_+_56117702 1.28 ENST00000559044.5
pellino E3 ubiquitin protein ligase family member 2
chr12_+_26195647 1.27 ENST00000535504.1
sarcospan
chr12_-_21910853 1.22 ENST00000544039.5
ATP binding cassette subfamily C member 9
chr5_+_90474879 1.21 ENST00000504930.5
ENST00000514483.5
RNA polymerase III subunit G
chr15_+_22015233 1.21 ENST00000639059.1
ENST00000640156.1
novel protein
novel transcript
chr11_-_117316230 1.21 ENST00000313005.11
ENST00000528053.5
beta-secretase 1
chr12_+_26195313 1.20 ENST00000422622.3
sarcospan
chr9_+_122370523 1.20 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chr18_+_23873000 1.20 ENST00000269217.11
ENST00000587184.5
laminin subunit alpha 3
chr5_+_90474848 1.19 ENST00000651687.1
RNA polymerase III subunit G
chr14_+_103385450 1.19 ENST00000416682.6
microtubule affinity regulating kinase 3
chr2_+_181986015 1.16 ENST00000409702.1
protein phosphatase 1 regulatory inhibitor subunit 1C
chr9_+_121567057 1.14 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2 interacting protein
chr20_-_57690624 1.08 ENST00000414037.5
prostate transmembrane protein, androgen induced 1
chr1_-_197146620 1.08 ENST00000367409.9
ENST00000680265.1
assembly factor for spindle microtubules
chr3_-_185821092 1.07 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chrX_-_101407893 1.05 ENST00000676156.1
ENST00000675592.1
ENST00000674634.2
ENST00000649178.1
ENST00000218516.4
galactosidase alpha
chr4_-_39977836 1.03 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr7_+_107583919 1.03 ENST00000491150.5
B cell receptor associated protein 29
chr6_-_110179995 0.99 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASP family member 1
chr19_+_53962925 0.99 ENST00000270458.4
calcium voltage-gated channel auxiliary subunit gamma 8
chr11_+_35180279 0.97 ENST00000531873.5
CD44 molecule (Indian blood group)
chr14_-_106038355 0.95 ENST00000390597.3
immunoglobulin heavy variable 2-5
chr17_+_35587478 0.94 ENST00000618940.4
adaptor related protein complex 2 subunit beta 1
chr6_+_113857333 0.92 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr14_+_24171853 0.90 ENST00000620473.4
ENST00000557806.5
ENST00000611366.5
REC8 meiotic recombination protein
chr15_+_67125707 0.90 ENST00000540846.6
SMAD family member 3
chr2_-_89085787 0.87 ENST00000390252.2
immunoglobulin kappa variable 3-15
chr7_+_134745460 0.86 ENST00000436461.6
caldesmon 1
chr2_+_90234809 0.86 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr3_-_142029108 0.86 ENST00000497579.5
transcription factor Dp-2
chr12_+_26195543 0.85 ENST00000242729.7
sarcospan
chr6_-_82247697 0.85 ENST00000306270.12
ENST00000610980.4
inhibitor of Bruton tyrosine kinase
chr1_+_152811971 0.84 ENST00000360090.4
late cornified envelope 1B
chr1_-_13116854 0.83 ENST00000621994.3
heterogeneous nuclear ribonucleoprotein C like 2
chr20_-_52105644 0.83 ENST00000371523.8
ZFP64 zinc finger protein
chrX_-_72239022 0.81 ENST00000373657.2
ENST00000334463.4
ERCC excision repair 6 like, spindle assembly checkpoint helicase
chr2_+_181985846 0.81 ENST00000682840.1
ENST00000409137.7
ENST00000280295.7
protein phosphatase 1 regulatory inhibitor subunit 1C
chr4_+_168497066 0.79 ENST00000261509.10
palladin, cytoskeletal associated protein
chr4_-_103076688 0.79 ENST00000394785.9
solute carrier family 9 member B2
chr1_-_197146688 0.78 ENST00000294732.11
assembly factor for spindle microtubules
chr11_-_69819410 0.78 ENST00000334134.4
fibroblast growth factor 3
chr11_+_55811367 0.76 ENST00000625203.2
olfactory receptor family 5 subfamily L member 1
chr6_+_29111560 0.76 ENST00000377169.2
olfactory receptor family 2 subfamily J member 3
chr8_-_30812867 0.75 ENST00000518243.5
protein phosphatase 2 catalytic subunit beta
chr4_+_70226116 0.74 ENST00000317987.6
follicular dendritic cell secreted protein
chr7_-_87713287 0.73 ENST00000416177.1
ENST00000265724.8
ENST00000543898.5
ATP binding cassette subfamily B member 1
chr2_+_87338511 0.73 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr4_+_168497044 0.73 ENST00000505667.6
palladin, cytoskeletal associated protein
chr4_+_25160631 0.72 ENST00000510415.1
ENST00000507794.2
ENST00000512921.4
SEPSECS antisense RNA 1 (head to head)
phosphatidylinositol 4-kinase type 2 beta
chr14_+_103385374 0.72 ENST00000678179.1
ENST00000676938.1
ENST00000678619.1
ENST00000440884.7
ENST00000560417.6
ENST00000679330.1
ENST00000556744.2
ENST00000676897.1
ENST00000677560.1
ENST00000561314.6
ENST00000677829.1
ENST00000677133.1
ENST00000676645.1
ENST00000678175.1
ENST00000429436.7
ENST00000677360.1
ENST00000678237.1
ENST00000677347.1
ENST00000677432.1
microtubule affinity regulating kinase 3
chr4_-_119322128 0.72 ENST00000274024.4
fatty acid binding protein 2
chrX_-_18672101 0.71 ENST00000379984.4
retinoschisin 1
chr6_+_47781982 0.71 ENST00000489301.6
ENST00000638973.1
ENST00000371211.6
ENST00000393699.2
opsin 5
chr2_-_88979016 0.71 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr5_-_16916400 0.71 ENST00000513882.5
myosin X
chr11_+_57597563 0.70 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr18_+_44700796 0.70 ENST00000677130.1
SET binding protein 1
chr14_+_35122660 0.69 ENST00000603544.5
protein only RNase P catalytic subunit
chr17_-_59151794 0.69 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr1_+_155308930 0.67 ENST00000465559.5
ENST00000612683.1
farnesyl diphosphate synthase
chr3_-_149377637 0.67 ENST00000305366.8
transmembrane 4 L six family member 1
chr5_+_58491427 0.67 ENST00000396776.6
ENST00000502276.6
ENST00000511930.2
GRB2 binding adaptor protein, transmembrane
chr1_+_157993273 0.67 ENST00000360089.8
ENST00000368173.7
kirre like nephrin family adhesion molecule 1
chr17_-_445939 0.67 ENST00000329099.4
refilin B
chr5_+_58491451 0.65 ENST00000513924.2
ENST00000515443.2
GRB2 binding adaptor protein, transmembrane
chr4_+_155666718 0.64 ENST00000621234.4
ENST00000511108.5
guanylate cyclase 1 soluble subunit alpha 1
chr13_-_23433676 0.64 ENST00000682547.1
ENST00000455470.6
ENST00000382292.9
sacsin molecular chaperone
chr11_-_7796942 0.64 ENST00000329434.3
olfactory receptor family 5 subfamily P member 2
chr1_-_153150884 0.63 ENST00000368748.5
small proline rich protein 2G
chr15_-_19988117 0.62 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr12_-_68225806 0.62 ENST00000229134.5
interleukin 26
chr11_+_55827219 0.61 ENST00000378397.1
olfactory receptor family 5 subfamily L member 2
chr1_+_155308748 0.60 ENST00000611010.4
ENST00000447866.5
ENST00000368356.9
ENST00000467076.5
ENST00000491013.5
ENST00000356657.10
farnesyl diphosphate synthase
chr11_-_14891643 0.60 ENST00000532378.5
cytochrome P450 family 2 subfamily R member 1
chr13_-_23433735 0.60 ENST00000423156.2
ENST00000683210.1
ENST00000682775.1
ENST00000684497.1
ENST00000682944.1
ENST00000683489.1
ENST00000684385.1
ENST00000683680.1
sacsin molecular chaperone
chr14_-_106211453 0.60 ENST00000390606.3
immunoglobulin heavy variable 3-20
chr13_-_75366973 0.60 ENST00000648194.1
TBC1 domain family member 4
chrX_+_7219431 0.59 ENST00000674499.1
ENST00000217961.5
steroid sulfatase
chr4_-_103077282 0.59 ENST00000503230.5
ENST00000503818.1
solute carrier family 9 member B2
chr18_-_26863187 0.58 ENST00000440832.7
aquaporin 4
chr17_-_47189176 0.58 ENST00000531206.5
ENST00000527547.5
ENST00000575483.5
ENST00000066544.8
cell division cycle 27
chr14_+_94561435 0.58 ENST00000557004.6
ENST00000555095.5
ENST00000298841.5
ENST00000554220.5
ENST00000553780.5
serpin family A member 4
serpin family A member 5
chr2_-_40453438 0.57 ENST00000455476.5
solute carrier family 8 member A1
chr8_-_7430348 0.57 ENST00000318124.3
defensin beta 103B
chr2_-_89027700 0.56 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr19_-_42427379 0.56 ENST00000244289.9
lipase E, hormone sensitive type
chr3_-_20012250 0.56 ENST00000389050.5
protein phosphatase 2C like domain containing 1
chr11_-_55936400 0.56 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr10_+_18400562 0.55 ENST00000377315.5
ENST00000650685.1
calcium voltage-gated channel auxiliary subunit beta 2
chr20_+_45416551 0.55 ENST00000639292.1
phosphatidylinositol glycan anchor biosynthesis class T
chrX_-_103255117 0.55 ENST00000372685.8
ENST00000360000.8
ENST00000451678.1
transcription elongation factor A like 8
chr7_+_120988683 0.55 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr16_+_28878480 0.54 ENST00000395503.9
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr14_+_30577752 0.54 ENST00000547532.5
ENST00000555429.1
G2/M-phase specific E3 ubiquitin protein ligase
chr14_-_80231052 0.54 ENST00000557010.5
iodothyronine deiodinase 2
chr8_-_48921419 0.53 ENST00000020945.4
snail family transcriptional repressor 2
chr8_-_42768602 0.53 ENST00000534622.5
cholinergic receptor nicotinic alpha 6 subunit
chr1_-_66801276 0.53 ENST00000304526.3
insulin like 5
chr7_+_116222804 0.53 ENST00000393481.6
testin LIM domain protein
chr8_-_30812773 0.53 ENST00000221138.9
protein phosphatase 2 catalytic subunit beta
chr14_-_106593319 0.52 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr4_+_168631597 0.52 ENST00000504519.5
ENST00000512127.5
palladin, cytoskeletal associated protein
chrX_+_44844015 0.51 ENST00000339042.6
dual specificity phosphatase 21
chr4_-_102828048 0.51 ENST00000508249.1
ubiquitin conjugating enzyme E2 D3
chr6_+_128883114 0.51 ENST00000421865.3
ENST00000618192.4
ENST00000617695.4
laminin subunit alpha 2
chr8_-_33567118 0.50 ENST00000256257.2
ring finger protein 122
chr4_+_118888918 0.50 ENST00000434046.6
synaptopodin 2
chr1_+_115029823 0.49 ENST00000256592.3
thyroid stimulating hormone subunit beta
chr11_-_5301946 0.49 ENST00000380224.2
olfactory receptor family 51 subfamily B member 4
chr7_-_111392915 0.49 ENST00000450877.5
inner mitochondrial membrane peptidase subunit 2
chr5_-_177462379 0.48 ENST00000512501.1
drebrin 1
chr17_+_47651061 0.48 ENST00000540627.5
karyopherin subunit beta 1
chr8_+_104223320 0.48 ENST00000339750.3
regulating synaptic membrane exocytosis 2
chr6_+_43427535 0.48 ENST00000372530.9
ATP binding cassette subfamily C member 10
chr19_-_3557563 0.47 ENST00000389395.7
ENST00000355415.7
major facilitator superfamily domain containing 12
chr1_-_201171545 0.47 ENST00000367333.6
transmembrane protein 9
chr4_-_102828022 0.47 ENST00000502690.5
ubiquitin conjugating enzyme E2 D3
chr3_+_111999326 0.46 ENST00000494932.1
transgelin 3
chrX_-_101617921 0.46 ENST00000361910.9
ENST00000538627.5
ENST00000539247.5
armadillo repeat containing X-linked 6
chr13_-_35476682 0.46 ENST00000379919.6
mab-21 like 1
chr15_-_91022540 0.46 ENST00000333371.8
ENST00000535906.1
VPS33B late endosome and lysosome associated
chr2_+_86907953 0.45 ENST00000409776.6
RANBP2 like and GRIP domain containing 1
chr12_+_8157034 0.45 ENST00000396570.7
zinc finger protein 705A
chr17_-_74776323 0.45 ENST00000582870.5
ENST00000581136.5
ENST00000579218.5
ENST00000583476.5
ENST00000580301.5
ENST00000583757.5
ENST00000357814.8
ENST00000582524.5
N-acetyltransferase 9 (putative)
chr6_-_38703066 0.45 ENST00000373365.5
glyoxalase I
chr15_+_94355956 0.45 ENST00000557742.1
multiple C2 and transmembrane domain containing 2
chr16_-_55833085 0.44 ENST00000360526.8
carboxylesterase 1
chr8_+_7881387 0.44 ENST00000314357.4
defensin beta 103A
chr4_+_70050431 0.44 ENST00000511674.5
ENST00000246896.8
histatin 1
chr2_+_108377947 0.43 ENST00000272452.7
sulfotransferase family 1C member 4
chr11_-_11353241 0.43 ENST00000528848.3
casein kinase 2 alpha 3
chr10_+_18260715 0.43 ENST00000615785.4
ENST00000617363.4
ENST00000396576.6
calcium voltage-gated channel auxiliary subunit beta 2
chr20_-_1466822 0.42 ENST00000353088.6
ENST00000216879.9
NSFL1 cofactor
chr6_+_63521738 0.42 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr13_+_31739542 0.42 ENST00000380314.2
relaxin family peptide receptor 2
chr2_+_233729042 0.41 ENST00000482026.6
UDP glucuronosyltransferase family 1 member A3
chr19_-_14848922 0.40 ENST00000641129.1
olfactory receptor family 7 subfamily A member 10
chr12_-_11134644 0.40 ENST00000539585.1
taste 2 receptor member 30
chrX_+_37780049 0.39 ENST00000378588.5
cytochrome b-245 beta chain
chr12_+_26011713 0.39 ENST00000542004.5
Ras association domain family member 8
chr3_-_46208304 0.39 ENST00000296140.4
C-C motif chemokine receptor 1
chr1_+_76867469 0.38 ENST00000477717.6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr3_+_111998739 0.38 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr17_+_41966787 0.38 ENST00000393892.8
ENST00000587679.1
2',3'-cyclic nucleotide 3' phosphodiesterase
chr4_+_89901979 0.38 ENST00000508372.1
multimerin 1
chr4_-_89836213 0.37 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chr3_+_111999189 0.37 ENST00000455401.6
transgelin 3
chr17_+_35587239 0.37 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
adaptor related protein complex 2 subunit beta 1
chr2_+_90069662 0.37 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chrX_+_30243715 0.37 ENST00000378981.8
ENST00000397550.6
MAGE family member B1
chr17_+_41966814 0.36 ENST00000393888.1
ENST00000441615.2
2',3'-cyclic nucleotide 3' phosphodiesterase
chr19_-_35812838 0.36 ENST00000653904.2
proline dehydrogenase 2
chr20_-_35147285 0.36 ENST00000374491.3
ENST00000374492.8
ER degradation enhancing alpha-mannosidase like protein 2
chr7_+_141738321 0.36 ENST00000612337.4
single stranded DNA binding protein 1
chr14_+_35122722 0.36 ENST00000605870.5
ENST00000557404.3
protein only RNase P catalytic subunit
chrX_-_139642889 0.35 ENST00000370576.9
MCF.2 cell line derived transforming sequence
chr20_-_1466904 0.35 ENST00000476071.5
NSFL1 cofactor
chr13_+_30422487 0.35 ENST00000638137.1
ENST00000635918.2
ubiquitin conjugating enzyme E2 L5
chr3_-_151316795 0.35 ENST00000260843.5
G protein-coupled receptor 87
chr14_+_71933116 0.34 ENST00000553530.5
ENST00000556437.5
regulator of G protein signaling 6
chr19_-_43883964 0.34 ENST00000587539.2
zinc finger protein 404
chr4_+_109827963 0.34 ENST00000317735.7
retinal pigment epithelium-derived rhodopsin homolog
chr12_-_91058016 0.34 ENST00000266719.4
keratocan
chrX_+_154304923 0.34 ENST00000426989.5
ENST00000426203.5
ENST00000369912.2
transketolase like 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.7 GO:0060005 vestibular reflex(GO:0060005)
0.7 7.9 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.5 3.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.5 1.9 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.5 2.3 GO:0030035 microspike assembly(GO:0030035)
0.4 1.6 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.3 5.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 1.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 1.3 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.2 1.9 GO:0051541 elastin metabolic process(GO:0051541)
0.2 0.7 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 0.7 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.2 1.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.2 5.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.2 0.7 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.2 0.5 GO:0031443 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.2 0.4 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 0.5 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 1.8 GO:0035878 nail development(GO:0035878)
0.2 2.9 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 1.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 2.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 0.5 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 1.9 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 1.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.9 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 2.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.4 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 1.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 1.0 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.6 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.6 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.5 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 1.0 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 1.0 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.6 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 2.0 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.5 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.6 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.7 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 1.0 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 3.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.2 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.1 0.5 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 0.4 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.3 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.6 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.2 GO:0014034 neural crest cell fate commitment(GO:0014034) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 1.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.4 GO:2000470 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.4 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.3 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161) regulation of collagen catabolic process(GO:0010710)
0.1 0.2 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 1.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.8 GO:0044557 relaxation of smooth muscle(GO:0044557)
0.1 0.4 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.1 1.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 2.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.2 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.0 0.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.5 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.9 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 1.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 2.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 2.0 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 5.5 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.5 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.7 GO:0009642 response to light intensity(GO:0009642)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.4 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.3 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.5 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.9 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.3 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 1.2 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.8 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.3 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.6 GO:0006833 water transport(GO:0006833)
0.0 0.1 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.8 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 3.3 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.6 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 2.2 GO:0070268 cornification(GO:0070268)
0.0 1.4 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.4 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 2.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.5 GO:0055026 negative regulation of cardiac muscle tissue development(GO:0055026)
0.0 0.5 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.9 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.8 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.1 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0002839 positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.9 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.5 8.5 GO:0032426 stereocilium tip(GO:0032426)
0.4 1.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.3 0.9 GO:0001674 female germ cell nucleus(GO:0001674)
0.3 1.1 GO:1990032 parallel fiber(GO:1990032)
0.2 0.9 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.2 1.9 GO:0072687 meiotic spindle(GO:0072687)
0.2 0.8 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.2 2.9 GO:0030478 actin cap(GO:0030478)
0.2 0.6 GO:0097180 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.2 1.2 GO:0005610 laminin-5 complex(GO:0005610)
0.2 3.8 GO:0030056 hemidesmosome(GO:0030056)
0.2 1.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.5 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.2 GO:0070852 cell body fiber(GO:0070852)
0.1 0.3 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.3 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.1 2.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 3.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.9 GO:0030057 desmosome(GO:0030057)
0.1 0.3 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 6.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.2 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.7 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 1.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.7 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.5 GO:0071439 clathrin complex(GO:0071439)
0.0 2.0 GO:0002102 podosome(GO:0002102)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 1.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 1.7 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.8 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.0 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 1.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.6 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0002113 interleukin-33 binding(GO:0002113)
1.1 5.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.6 8.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.5 1.4 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.3 1.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 1.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.3 1.3 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 0.7 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.2 2.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 1.0 GO:0016936 galactoside binding(GO:0016936)
0.2 0.6 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 1.4 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 3.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.2 0.6 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.9 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.6 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.1 0.7 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.7 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 2.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.8 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 2.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.7 GO:0005549 odorant binding(GO:0005549)
0.1 0.9 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 2.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0004802 transketolase activity(GO:0004802)
0.1 2.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.3 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 1.0 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 1.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 1.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 7.9 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.6 GO:0032190 acrosin binding(GO:0032190)
0.1 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 2.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 1.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 2.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.3 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.6 GO:0015250 water channel activity(GO:0015250)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.6 GO:0050699 WW domain binding(GO:0050699)
0.0 1.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 1.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 3.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 2.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 4.0 GO:0003823 antigen binding(GO:0003823)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.0 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.8 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.9 GO:0048365 Rac GTPase binding(GO:0048365)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.6 PID FOXO PATHWAY FoxO family signaling
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.9 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 2.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.8 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.0 REACTOME OPSINS Genes involved in Opsins
0.1 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 6.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 8.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 4.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.8 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 1.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 2.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP