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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXB7

Z-value: 0.71

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Transcription factors associated with HOXB7

Gene Symbol Gene ID Gene Info
ENSG00000260027.5 HOXB7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB7hg38_v1_chr17_-_48610971_48611023-0.337.1e-02Click!

Activity profile of HOXB7 motif

Sorted Z-values of HOXB7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB7

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_46046264 2.38 ENST00000581478.5
ENST00000582163.3
microseminoprotein beta
chr16_-_67393486 1.99 ENST00000562206.1
ENST00000393957.7
ENST00000290942.9
tubulin polymerization promoting protein family member 3
chr10_-_13099652 1.88 ENST00000378839.1
coiled-coil domain containing 3
chr1_-_103696209 1.70 ENST00000330330.10
amylase alpha 1B
chr1_+_103617427 1.64 ENST00000423678.2
ENST00000414303.7
amylase alpha 2A
chr1_+_103750406 1.54 ENST00000370079.3
amylase alpha 1C
chr16_-_21278282 1.52 ENST00000572914.2
crystallin mu
chr12_-_91111460 1.51 ENST00000266718.5
lumican
chr3_-_149221811 1.51 ENST00000455472.3
ENST00000264613.11
ceruloplasmin
chr12_+_20815672 1.50 ENST00000261196.6
ENST00000381541.7
ENST00000540229.1
solute carrier organic anion transporter family member 1B3
SLCO1B3-SLCO1B7 readthrough
chr1_+_103655760 1.48 ENST00000370083.9
amylase alpha 1A
chr9_-_34397800 1.45 ENST00000297623.7
chromosome 9 open reading frame 24
chr12_-_91179355 1.28 ENST00000550563.5
ENST00000546370.5
decorin
chr1_+_103749898 1.24 ENST00000622339.5
amylase alpha 1C
chr11_-_63608542 1.23 ENST00000540943.1
phospholipase A and acyltransferase 3
chr2_-_153478753 1.21 ENST00000325926.4
reprimo, TP53 dependent G2 arrest mediator homolog
chr4_+_68815991 1.14 ENST00000265403.12
ENST00000458688.2
UDP glucuronosyltransferase family 2 member B10
chr15_-_93073111 1.13 ENST00000557420.1
ENST00000542321.6
repulsive guidance molecule BMP co-receptor a
chr1_+_218345326 1.09 ENST00000366930.9
transforming growth factor beta 2
chr4_-_99435396 0.99 ENST00000209665.8
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr4_+_41613476 0.97 ENST00000508466.1
LIM and calponin homology domains 1
chr5_+_140848360 0.97 ENST00000532602.2
protocadherin alpha 9
chr9_+_72114595 0.93 ENST00000545168.5
guanine deaminase
chr3_-_93973933 0.91 ENST00000650591.1
protein S
chr4_-_117085541 0.91 ENST00000310754.5
translocation associated membrane protein 1 like 1
chr9_+_102995308 0.86 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
cylicin 2
chr1_+_111473972 0.81 ENST00000369718.4
chromosome 1 open reading frame 162
chr1_+_111473792 0.79 ENST00000343534.9
chromosome 1 open reading frame 162
chr3_-_93973833 0.76 ENST00000348974.5
ENST00000647936.1
ENST00000394236.9
ENST00000407433.6
protein S
chr7_-_120858303 0.75 ENST00000415871.5
ENST00000430985.1
tetraspanin 12
chr2_+_63050813 0.73 ENST00000282549.7
orthodenticle homeobox 1
chr4_-_99435336 0.72 ENST00000437033.7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr19_+_49513353 0.71 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr7_-_138679045 0.67 ENST00000419765.4
SVOP like
chr10_+_122560639 0.66 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
deleted in malignant brain tumors 1
chrX_+_9463272 0.66 ENST00000407597.7
ENST00000380961.5
ENST00000424279.6
transducin beta like 1 X-linked
chr7_+_141995872 0.66 ENST00000497673.5
ENST00000620571.1
ENST00000475668.6
maltase-glucoamylase
chr4_-_69214743 0.66 ENST00000446444.2
UDP glucuronosyltransferase family 2 member B11
chr20_+_37903104 0.64 ENST00000373459.4
ENST00000373461.9
ENST00000448944.1
V-set and transmembrane domain containing 2 like
chr10_+_122560679 0.63 ENST00000657942.1
deleted in malignant brain tumors 1
chr12_+_101594849 0.61 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr10_-_121598412 0.60 ENST00000360144.7
ENST00000358487.10
ENST00000369059.5
ENST00000613048.4
ENST00000356226.8
fibroblast growth factor receptor 2
chr2_+_26401909 0.59 ENST00000288710.7
dynein regulatory complex subunit 1
chr17_+_21126947 0.58 ENST00000579303.5
dehydrogenase/reductase 7B
chr3_+_181711915 0.57 ENST00000325404.3
SRY-box transcription factor 2
chr2_-_27663817 0.57 ENST00000404798.6
SPT7 like, STAGA complex subunit gamma
chr16_-_28623560 0.55 ENST00000350842.8
sulfotransferase family 1A member 1
chr1_-_152159227 0.55 ENST00000316073.3
repetin
chr22_-_17258235 0.54 ENST00000649310.1
ENST00000649746.1
adenosine deaminase 2
chr10_+_122560751 0.54 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chr1_-_152115443 0.53 ENST00000614923.1
trichohyalin
chr3_+_141228721 0.53 ENST00000505013.5
2-phosphoxylose phosphatase 1
chr3_-_58627596 0.52 ENST00000474531.5
ENST00000465970.1
family with sequence similarity 107 member A
chr17_+_1771688 0.49 ENST00000572048.1
ENST00000573763.1
serpin family F member 1
chr4_+_69280472 0.49 ENST00000335568.10
ENST00000511240.1
UDP glucuronosyltransferase family 2 member B28
chr10_+_68109433 0.49 ENST00000613327.4
ENST00000358913.10
ENST00000373675.3
myopalladin
chr4_-_176195563 0.48 ENST00000280191.7
spermatogenesis associated 4
chr19_+_13023958 0.48 ENST00000587760.5
ENST00000585575.5
nuclear factor I X
chr7_+_30145789 0.48 ENST00000324489.5
maturin, neural progenitor differentiation regulator homolog
chr8_+_103880412 0.47 ENST00000436393.6
regulating synaptic membrane exocytosis 2
chr2_+_119679154 0.47 ENST00000401466.5
ENST00000424086.5
transmembrane protein 177
chr2_+_119679184 0.47 ENST00000445518.1
ENST00000272521.7
ENST00000409951.1
transmembrane protein 177
chr4_-_99435134 0.47 ENST00000476959.5
ENST00000482593.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr3_+_189789672 0.46 ENST00000434928.5
tumor protein p63
chr12_-_14951106 0.45 ENST00000541644.5
ENST00000545895.5
Rho GDP dissociation inhibitor beta
chr12_-_91179472 0.45 ENST00000550099.5
ENST00000546391.5
decorin
chr2_-_27663594 0.44 ENST00000337768.10
ENST00000405491.5
ENST00000464789.2
ENST00000406540.5
SPT7 like, STAGA complex subunit gamma
chr14_+_73950489 0.44 ENST00000554320.1
coenzyme Q6, monooxygenase
chr10_+_116545907 0.44 ENST00000369221.2
pancreatic lipase
chr18_+_58196736 0.44 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr3_-_112845950 0.43 ENST00000398214.5
CD200 receptor 1 like
chr4_+_76435216 0.42 ENST00000296043.7
shroom family member 3
chr2_+_89947508 0.42 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr20_+_59996335 0.41 ENST00000244049.7
ENST00000350849.10
ENST00000456106.1
cadherin 26
chr7_+_117014881 0.41 ENST00000422922.5
ENST00000432298.5
suppression of tumorigenicity 7
chr5_+_161685708 0.40 ENST00000274545.10
gamma-aminobutyric acid type A receptor subunit alpha6
chr5_+_161685748 0.40 ENST00000523217.5
gamma-aminobutyric acid type A receptor subunit alpha6
chr5_+_141392616 0.39 ENST00000398604.3
protocadherin gamma subfamily A, 8
chr6_-_152563271 0.39 ENST00000535896.7
ENST00000672122.1
spectrin repeat containing nuclear envelope protein 1
chr20_+_15196834 0.38 ENST00000402914.5
mono-ADP ribosylhydrolase 2
chr19_-_52095704 0.38 ENST00000594440.6
ENST00000426391.6
zinc finger protein 841
chr10_+_68106109 0.38 ENST00000540630.5
ENST00000354393.6
myopalladin
chr18_+_46946821 0.38 ENST00000245121.9
ENST00000356157.12
katanin catalytic subunit A1 like 2
chr15_-_85794902 0.37 ENST00000337975.6
kelch like family member 25
chr3_-_58627567 0.37 ENST00000649301.1
family with sequence similarity 107 member A
chr17_-_8867639 0.37 ENST00000619866.5
phosphoinositide-3-kinase regulatory subunit 6
chr6_+_47656436 0.37 ENST00000507065.5
ENST00000296862.5
adhesion G protein-coupled receptor F2
chr1_-_27914513 0.36 ENST00000313433.11
ENST00000373912.8
ENST00000444045.1
replication protein A2
chr16_-_66550142 0.36 ENST00000417693.8
ENST00000299697.12
ENST00000451102.7
thymidine kinase 2
chr8_-_107498041 0.36 ENST00000297450.7
angiopoietin 1
chr8_-_107497909 0.36 ENST00000517746.6
angiopoietin 1
chr6_+_89562308 0.35 ENST00000522441.5
ankyrin repeat domain 6
chr12_-_64752871 0.35 ENST00000418919.6
glucosamine (N-acetyl)-6-sulfatase
chr13_-_109786567 0.34 ENST00000375856.5
insulin receptor substrate 2
chr19_-_14835252 0.33 ENST00000641666.1
ENST00000642030.1
ENST00000642000.1
olfactory receptor family 7 subfamily C member 1
chr11_-_19060706 0.33 ENST00000329773.3
MAS related GPR family member X2
chr16_-_66550112 0.33 ENST00000544898.6
ENST00000620035.5
ENST00000545043.6
thymidine kinase 2
chr3_+_141386862 0.31 ENST00000513258.5
zinc finger and BTB domain containing 38
chr2_-_96505345 0.31 ENST00000310865.7
ENST00000451794.6
neuralized E3 ubiquitin protein ligase 3
chr9_+_137241277 0.30 ENST00000340384.5
tubulin beta 4B class IVb
chr1_+_107141022 0.29 ENST00000370067.5
ENST00000370068.6
netrin G1
chr3_+_148827800 0.29 ENST00000282957.9
ENST00000468341.1
carboxypeptidase B1
chr3_-_142448004 0.29 ENST00000463916.5
5'-3' exoribonuclease 1
chr2_-_86105839 0.28 ENST00000263857.11
RNA polymerase I subunit A
chr20_+_5950931 0.28 ENST00000265187.4
ENST00000652720.1
minichromosome maintenance 8 homologous recombination repair factor
novel protein
chr21_-_30216047 0.28 ENST00000399899.2
claudin 8
chr7_-_124765753 0.28 ENST00000303921.3
G protein-coupled receptor 37
chr8_+_97775775 0.28 ENST00000521545.7
lysosomal protein transmembrane 4 beta
chr2_-_216081759 0.27 ENST00000265322.8
peroxisomal trans-2-enoyl-CoA reductase
chr1_+_19596960 0.27 ENST00000617872.4
ENST00000322753.7
ENST00000602662.1
mitochondrial contact site and cristae organizing system subunit 10
NBL1, DAN family BMP antagonist
chr3_-_161372821 0.27 ENST00000617024.1
ENST00000359175.8
serine palmitoyltransferase small subunit B
chr3_-_185552554 0.27 ENST00000424591.6
ENST00000296252.9
lipase H
chr19_-_20565746 0.27 ENST00000594419.1
zinc finger protein 737
chr16_+_86566821 0.26 ENST00000649859.1
forkhead box C2
chr1_-_241357171 0.26 ENST00000440928.6
regulator of G protein signaling 7
chr14_+_24114627 0.26 ENST00000559115.5
ENST00000558215.5
ENST00000557810.5
ENST00000561375.5
ENST00000446197.8
ENST00000559796.5
ENST00000560713.5
ENST00000560901.5
ENST00000559382.5
ENST00000561001.5
DDB1 and CUL4 associated factor 11
chr17_-_41140487 0.26 ENST00000345847.4
keratin associated protein 4-6
chr6_+_50818701 0.26 ENST00000344788.7
transcription factor AP-2 beta
chr14_+_19743571 0.25 ENST00000642117.2
olfactory receptor family 4 subfamily Q member 3
chr1_-_202808432 0.25 ENST00000649200.1
ENST00000650493.1
lysine demethylase 5B
chr19_+_37346283 0.25 ENST00000541583.6
zinc finger protein 875
chr1_-_107965009 0.25 ENST00000527011.5
ENST00000370056.9
vav guanine nucleotide exchange factor 3
chr16_+_77722502 0.25 ENST00000564085.5
ENST00000268533.9
ENST00000568787.5
ENST00000437314.3
ENST00000563839.1
nudix hydrolase 7
chr1_-_241357225 0.24 ENST00000366565.5
regulator of G protein signaling 7
chr5_-_83673544 0.24 ENST00000503117.1
ENST00000510978.5
hyaluronan and proteoglycan link protein 1
chr16_+_16340328 0.24 ENST00000524823.6
novel member of the nuclear pore complex interacting protein NPIP gene family
chr18_-_55423757 0.24 ENST00000675707.1
transcription factor 4
chr9_+_65700287 0.23 ENST00000489273.1
COBW domain containing 5
chr16_-_71484543 0.23 ENST00000565100.6
zinc finger protein 19
chr14_+_23469681 0.23 ENST00000408901.8
ENST00000397154.7
ENST00000555128.5
neuroguidin
chr14_-_100569780 0.23 ENST00000355173.7
brain enriched guanylate kinase associated
chr5_-_139198358 0.23 ENST00000394817.7
SIL1 nucleotide exchange factor
chr19_+_18919688 0.22 ENST00000247003.9
DEAD-box helicase 49
chr8_-_18887018 0.22 ENST00000523619.5
pleckstrin and Sec7 domain containing 3
chr10_+_116324440 0.22 ENST00000333254.4
coiled-coil domain containing 172
chr3_+_148791058 0.22 ENST00000491148.5
carboxypeptidase B1
chr16_-_84187026 0.22 ENST00000561955.1
ENST00000564454.1
ENST00000341690.10
ENST00000566732.6
ENST00000570117.5
ENST00000564345.5
ENST00000541676.5
TATA-box binding protein associated factor, RNA polymerase I subunit C
chr3_+_39383337 0.21 ENST00000650617.1
ENST00000431510.1
ENST00000645630.1
solute carrier family 25 member 38
chr19_-_20565769 0.21 ENST00000427401.9
zinc finger protein 737
chr10_+_101131284 0.21 ENST00000370196.11
ENST00000467928.2
T cell leukemia homeobox 1
chr14_-_23155302 0.21 ENST00000529705.6
solute carrier family 7 member 8
chr3_-_42410558 0.21 ENST00000441172.1
ENST00000287748.8
lysozyme like 4
chr16_-_84186998 0.21 ENST00000567759.5
TATA-box binding protein associated factor, RNA polymerase I subunit C
chr4_+_85827745 0.21 ENST00000509300.5
Rho GTPase activating protein 24
chr14_-_34462223 0.21 ENST00000298130.5
serine palmitoyltransferase small subunit A
chr6_-_31592992 0.20 ENST00000340027.10
natural cytotoxicity triggering receptor 3
chr11_+_96389985 0.20 ENST00000332349.5
JRK like
chr3_-_122993232 0.20 ENST00000650207.1
ENST00000616742.4
ENST00000393583.6
semaphorin 5B
chr1_+_12464912 0.20 ENST00000543766.2
vacuolar protein sorting 13 homolog D
chr15_-_37101205 0.20 ENST00000338564.9
ENST00000558313.5
ENST00000340545.9
Meis homeobox 2
chr9_-_146140 0.20 ENST00000475990.5
COBW domain containing 1
chr7_-_80919017 0.20 ENST00000265361.8
semaphorin 3C
chr11_+_57597563 0.20 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr2_-_108989206 0.20 ENST00000258443.7
ENST00000409271.5
ENST00000376651.1
ectodysplasin A receptor
chr20_-_56497608 0.20 ENST00000617620.1
glucosaminyl (N-acetyl) transferase family member 7
chr16_-_66550091 0.19 ENST00000564917.5
ENST00000677420.1
thymidine kinase 2
chr5_-_139198284 0.19 ENST00000507002.5
ENST00000505830.5
ENST00000508639.5
ENST00000265195.9
SIL1 nucleotide exchange factor
chr8_+_97775829 0.19 ENST00000517924.5
lysosomal protein transmembrane 4 beta
chr3_-_142000353 0.19 ENST00000499676.5
transcription factor Dp-2
chr14_+_55611977 0.19 ENST00000395309.7
ENST00000413890.6
kinectin 1
chr11_+_72216774 0.19 ENST00000619261.4
ENST00000454954.6
ENST00000541003.5
ENST00000539412.5
ENST00000298223.11
ENST00000536778.5
ENST00000535625.5
ENST00000321324.11
folate receptor beta
chr17_-_7315312 0.19 ENST00000577040.2
ENST00000389167.9
ENST00000380728.7
G protein pathway suppressor 2
chr10_-_60572599 0.19 ENST00000503366.5
ankyrin 3
chr3_+_173398438 0.19 ENST00000457714.5
neuroligin 1
chr15_-_32455634 0.19 ENST00000509311.7
golgin A8 family member O
chr16_-_66550005 0.18 ENST00000527284.6
thymidine kinase 2
chrX_+_131058340 0.18 ENST00000276211.10
ENST00000370922.5
Rho GTPase activating protein 36
chr2_-_8837589 0.18 ENST00000319688.5
ENST00000489024.5
ENST00000256707.8
ENST00000473731.5
kinase D interacting substrate 220
chr4_-_99290975 0.18 ENST00000209668.3
alcohol dehydrogenase 1A (class I), alpha polypeptide
chrX_+_1615049 0.18 ENST00000381241.9
acetylserotonin O-methyltransferase
chr17_-_44915486 0.18 ENST00000638281.1
ENST00000588316.1
ENST00000588735.3
ENST00000639277.1
ENST00000253408.11
ENST00000435360.8
ENST00000586793.6
ENST00000588037.1
ENST00000592320.6
glial fibrillary acidic protein
chr1_-_100895132 0.18 ENST00000535414.5
exostosin like glycosyltransferase 2
chrX_+_1615158 0.18 ENST00000381229.9
ENST00000381233.8
acetylserotonin O-methyltransferase
chr2_+_233917371 0.17 ENST00000324695.9
ENST00000433712.6
transient receptor potential cation channel subfamily M member 8
chr1_-_111563934 0.17 ENST00000443498.5
transmembrane and immunoglobulin domain containing 3
chr10_+_102776237 0.17 ENST00000369889.5
WW domain binding protein 1 like
chr4_-_104494882 0.17 ENST00000394767.3
CXXC finger protein 4
chr8_-_18683932 0.17 ENST00000615573.4
pleckstrin and Sec7 domain containing 3
chr1_+_151047699 0.17 ENST00000368926.6
chromosome 1 open reading frame 56
chr11_+_31816266 0.17 ENST00000644607.1
ENST00000646221.1
ENST00000643671.1
ENST00000643931.1
ENST00000642614.1
ENST00000642818.1
ENST00000645848.1
ENST00000506388.2
ENST00000645824.1
ENST00000532942.5
PAX6 upstream antisense RNA
novel protein
chr12_+_110846960 0.17 ENST00000545036.5
ENST00000308208.10
coiled-coil domain containing 63
chr16_-_66549839 0.17 ENST00000527800.6
ENST00000677555.1
ENST00000563369.6
thymidine kinase 2
chr7_-_32490361 0.17 ENST00000410044.5
ENST00000450169.7
ENST00000409987.5
ENST00000409782.5
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr4_+_112818032 0.16 ENST00000672356.1
ENST00000672955.1
ankyrin 2
chr9_+_101398841 0.16 ENST00000339664.7
ENST00000374861.7
ENST00000259395.4
ENST00000615466.1
zinc finger protein 189
chr3_+_48223479 0.16 ENST00000652295.2
cathelicidin antimicrobial peptide
chr12_-_91153149 0.16 ENST00000550758.1
decorin
chr11_+_31812307 0.16 ENST00000643436.1
ENST00000646959.1
ENST00000645942.1
ENST00000530348.5
PAX6 upstream antisense RNA
novel protein
chr15_-_37098281 0.16 ENST00000559085.5
ENST00000397624.7
Meis homeobox 2
chr12_+_110847000 0.16 ENST00000552694.1
coiled-coil domain containing 63
chr5_+_93583212 0.16 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chrX_+_56563569 0.16 ENST00000338222.7
ubiquilin 2
chrM_+_9207 0.15 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr8_-_18684033 0.15 ENST00000614430.3
pleckstrin and Sec7 domain containing 3
chr17_+_7407838 0.15 ENST00000302926.7
neuroligin 2
chr2_-_55923775 0.15 ENST00000438672.5
ENST00000355426.8
ENST00000440439.5
ENST00000429909.5
ENST00000424207.5
ENST00000452337.5
ENST00000439193.5
ENST00000421664.1
EGF containing fibulin extracellular matrix protein 1
chr1_-_157598080 0.15 ENST00000271532.2
Fc receptor like 4
chr8_-_109974688 0.15 ENST00000297404.1
potassium voltage-gated channel modifier subfamily V member 1
chr8_-_18684093 0.15 ENST00000428502.6
pleckstrin and Sec7 domain containing 3
chr5_-_156935656 0.15 ENST00000406964.5
T cell immunoglobulin and mucin domain containing 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.4 1.1 GO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.3 2.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.3 0.9 GO:0006147 guanine catabolic process(GO:0006147)
0.2 0.7 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.2 0.7 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2 1.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.7 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.1 1.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 0.3 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.4 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 1.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.6 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.1 0.3 GO:0097274 ammonia homeostasis(GO:0097272) urea homeostasis(GO:0097274)
0.1 1.9 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 1.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.2 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.1 0.5 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.2 GO:0036233 glycine import(GO:0036233)
0.1 0.5 GO:0071279 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
0.1 0.3 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.1 0.3 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.3 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.2 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 1.9 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 0.5 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.6 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 1.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.2 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 1.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0071231 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) cellular response to folic acid(GO:0071231)
0.0 0.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0 0.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 1.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0070105 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.3 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.2 GO:1904021 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.0 0.9 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.5 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.4 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:1903538 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.3 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.9 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 2.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.4 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.4 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.0 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.3 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0009720 detection of hormone stimulus(GO:0009720)
0.0 0.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.2 GO:0051873 killing by host of symbiont cells(GO:0051873)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0033150 cytoskeletal calyx(GO:0033150)
0.2 2.0 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.4 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.3 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 0.5 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.5 GO:0043203 axon hillock(GO:0043203)
0.0 0.7 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 2.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.6 1.8 GO:0035375 zymogen binding(GO:0035375)
0.5 2.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.4 1.4 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.3 0.7 GO:0016160 amylase activity(GO:0016160)
0.3 0.9 GO:0008892 guanine deaminase activity(GO:0008892)
0.2 1.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.2 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0036505 prosaposin receptor activity(GO:0036505)
0.1 0.6 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.3 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 1.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.5 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 1.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 1.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.4 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 2.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.3 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 2.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.6 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway