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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXB8

Z-value: 1.00

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Transcription factors associated with HOXB8

Gene Symbol Gene ID Gene Info
ENSG00000120068.7 HOXB8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB8hg38_v1_chr17_-_48613468_48613522,
hg38_v1_chr17_-_48614628_48614704
0.154.4e-01Click!

Activity profile of HOXB8 motif

Sorted Z-values of HOXB8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB8

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_111595339 4.67 ENST00000317012.5
zinc finger BED-type containing 2
chr12_+_8822610 4.21 ENST00000299698.12
alpha-2-macroglobulin like 1
chr1_+_20589044 3.67 ENST00000375071.4
cytidine deaminase
chr9_+_33795551 3.67 ENST00000379405.4
serine protease 3
chr7_+_134843884 3.40 ENST00000445569.6
caldesmon 1
chr1_+_86547070 3.11 ENST00000370563.3
chloride channel accessory 4
chr8_-_90082871 2.79 ENST00000265431.7
calbindin 1
chr19_-_14778552 2.68 ENST00000315576.8
adhesion G protein-coupled receptor E2
chr15_-_79971164 2.52 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2 related protein A1
chr19_-_48513161 2.43 ENST00000673139.1
lemur tyrosine kinase 3
chr6_-_150025520 2.39 ENST00000367341.6
ENST00000286380.2
retinoic acid early transcript 1L
chr2_-_160200289 2.34 ENST00000409872.1
integrin subunit beta 6
chr4_+_74365136 2.27 ENST00000244869.3
epiregulin
chr1_+_171185293 2.27 ENST00000209929.10
flavin containing dimethylaniline monoxygenase 2
chr1_-_200620729 2.24 ENST00000367350.5
kinesin family member 14
chr1_+_24319342 2.23 ENST00000361548.9
grainyhead like transcription factor 3
chr14_+_35122660 2.23 ENST00000603544.5
protein only RNase P catalytic subunit
chr11_+_111245725 2.20 ENST00000280325.7
chromosome 11 open reading frame 53
chr15_-_74209019 2.19 ENST00000323940.9
signaling receptor and transporter of retinol STRA6
chr12_-_91111460 2.12 ENST00000266718.5
lumican
chr2_-_160200251 2.03 ENST00000428609.6
ENST00000409967.6
ENST00000283249.7
integrin subunit beta 6
chr6_-_131000722 1.97 ENST00000528282.5
erythrocyte membrane protein band 4.1 like 2
chr1_-_109740304 1.97 ENST00000540225.2
glutathione S-transferase mu 3
chr16_+_11345429 1.96 ENST00000576027.1
ENST00000312499.6
ENST00000648619.1
RecQ mediated genome instability 2
chr6_+_130018565 1.88 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr2_-_160200310 1.85 ENST00000620391.4
integrin subunit beta 6
chr12_-_95116967 1.85 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr8_+_7539627 1.85 ENST00000533250.2
proline rich 23 domain containing 1
chr4_-_48012934 1.82 ENST00000420489.7
ENST00000504722.6
cyclic nucleotide gated channel subunit alpha 1
chr5_+_148312416 1.80 ENST00000274565.5
serine peptidase inhibitor Kazal type 7
chr20_-_1329131 1.80 ENST00000360779.4
syndecan binding protein 2
chr1_+_84164962 1.76 ENST00000614872.4
ENST00000394839.6
protein kinase cAMP-activated catalytic subunit beta
chr9_+_102995308 1.71 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
cylicin 2
chr11_+_844406 1.70 ENST00000397404.5
tetraspanin 4
chr18_-_12656716 1.69 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
spire type actin nucleation factor 1
chr19_-_42877988 1.67 ENST00000597058.1
pregnancy specific beta-1-glycoprotein 1
chrX_-_154371210 1.63 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr9_+_122371036 1.63 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chr4_+_168092530 1.61 ENST00000359299.8
annexin A10
chr17_-_59151794 1.60 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr12_-_21910853 1.59 ENST00000544039.5
ATP binding cassette subfamily C member 9
chr3_+_100635598 1.55 ENST00000475887.1
adhesion G protein-coupled receptor G7
chr11_+_62856072 1.52 ENST00000377890.6
ENST00000681467.1
ENST00000538084.2
ENST00000681569.1
ENST00000377891.6
ENST00000680725.1
ENST00000377889.6
solute carrier family 3 member 2
chr11_+_5389377 1.49 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chr2_+_101839815 1.49 ENST00000421882.5
mitogen-activated protein kinase kinase kinase kinase 4
chr1_+_84181630 1.46 ENST00000610457.1
protein kinase cAMP-activated catalytic subunit beta
chr17_-_40937641 1.46 ENST00000209718.8
keratin 23
chr10_+_17228215 1.43 ENST00000544301.7
vimentin
chr16_-_88663065 1.43 ENST00000301012.8
ENST00000569177.5
mevalonate diphosphate decarboxylase
chr1_+_24319511 1.43 ENST00000356046.6
grainyhead like transcription factor 3
chr12_+_18242955 1.41 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr11_+_62856149 1.41 ENST00000535296.5
solute carrier family 3 member 2
chr4_+_143433491 1.40 ENST00000512843.1
GRB2 associated binding protein 1
chr1_-_209784521 1.40 ENST00000294811.2
chromosome 1 open reading frame 74
chr16_+_66603874 1.40 ENST00000563672.5
ENST00000424011.6
CKLF like MARVEL transmembrane domain containing 3
chr8_-_124565699 1.39 ENST00000519168.5
MTSS I-BAR domain containing 1
chr9_+_72577369 1.38 ENST00000651183.1
transmembrane channel like 1
chr7_-_86965872 1.37 ENST00000398276.6
ENST00000416314.5
ENST00000425689.1
endosome-lysosome associated apoptosis and autophagy regulator family member 2
chr11_+_57597563 1.37 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr12_-_27971970 1.36 ENST00000395872.5
ENST00000201015.8
parathyroid hormone like hormone
chr10_-_88952763 1.35 ENST00000224784.10
actin alpha 2, smooth muscle
chr12_-_54419259 1.32 ENST00000293379.9
integrin subunit alpha 5
chr16_+_55479188 1.30 ENST00000219070.9
matrix metallopeptidase 2
chr6_-_107824294 1.26 ENST00000369020.8
ENST00000369022.6
Scm polycomb group protein like 4
chr20_-_57711536 1.26 ENST00000265626.8
prostate transmembrane protein, androgen induced 1
chr3_+_102099244 1.24 ENST00000491959.5
zona pellucida like domain containing 1
chr12_+_56521990 1.23 ENST00000550726.5
ENST00000542360.1
RNA binding motif single stranded interacting protein 2
chr5_-_134367144 1.23 ENST00000265334.9
cyclin dependent kinase like 3
chr12_+_113244261 1.23 ENST00000392569.8
ENST00000552542.5
two pore segment channel 1
chr2_+_17539964 1.22 ENST00000457525.5
visinin like 1
chr11_-_55936400 1.21 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr14_-_106374129 1.19 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr19_-_7040179 1.17 ENST00000381394.9
methyl-CpG binding domain protein 3 like 4
chr3_+_155083889 1.17 ENST00000680282.1
membrane metalloendopeptidase
chr3_+_57890011 1.16 ENST00000494088.6
ENST00000438794.5
sarcolemma associated protein
chr10_-_88851809 1.16 ENST00000371930.5
ankyrin repeat domain 22
chr9_-_120877026 1.15 ENST00000436309.5
PHD finger protein 19
chr11_-_19060706 1.14 ENST00000329773.3
MAS related GPR family member X2
chr5_-_126595237 1.13 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr12_+_21372899 1.13 ENST00000240652.8
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr9_+_122371014 1.12 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chr15_+_67125707 1.10 ENST00000540846.6
SMAD family member 3
chr6_+_47698538 1.10 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr12_-_27972725 1.09 ENST00000545234.6
parathyroid hormone like hormone
chr10_+_13099440 1.09 ENST00000263036.9
optineurin
chr7_+_118184105 1.07 ENST00000424702.1
LSM8 homolog, U6 small nuclear RNA associated
chr7_+_134745460 1.07 ENST00000436461.6
caldesmon 1
chr22_+_44752552 1.06 ENST00000389774.6
ENST00000356099.11
ENST00000396119.6
ENST00000336963.8
ENST00000412433.5
Rho GTPase activating protein 8
chr6_+_47698574 1.06 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr19_+_41797147 1.05 ENST00000596544.1
CEA cell adhesion molecule 3
chr14_-_106025628 1.05 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr2_-_70553440 1.04 ENST00000450929.5
transforming growth factor alpha
chr16_-_20691256 1.02 ENST00000307493.8
acyl-CoA synthetase medium chain family member 1
chr11_+_44095710 1.02 ENST00000358681.8
ENST00000343631.4
ENST00000682711.1
exostosin glycosyltransferase 2
chr4_-_119322128 1.02 ENST00000274024.4
fatty acid binding protein 2
chr14_+_22508602 1.01 ENST00000390504.1
T cell receptor alpha joining 33
chr7_+_80646305 1.01 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr4_+_69280472 1.01 ENST00000335568.10
ENST00000511240.1
UDP glucuronosyltransferase family 2 member B28
chr19_-_43204223 1.00 ENST00000599746.5
pregnancy specific beta-1-glycoprotein 4
chr9_-_120876356 1.00 ENST00000456291.1
PHD finger protein 19
chr3_-_197226351 0.98 ENST00000656428.1
discs large MAGUK scaffold protein 1
chr8_-_7781413 0.98 ENST00000528972.1
proline rich 23 domain containing 2
chr7_-_93890160 0.97 ENST00000451238.1
tissue factor pathway inhibitor 2
chr9_+_5450503 0.96 ENST00000381573.8
ENST00000381577.4
CD274 molecule
chr8_+_127735597 0.95 ENST00000651626.1
MYC proto-oncogene, bHLH transcription factor
chr11_+_57598184 0.95 ENST00000677625.1
ENST00000676670.1
serpin family G member 1
chr7_+_107583919 0.94 ENST00000491150.5
B cell receptor associated protein 29
chr10_+_13099585 0.93 ENST00000378764.6
optineurin
chr11_-_2140967 0.93 ENST00000381389.5
insulin like growth factor 2
chr5_-_77492199 0.93 ENST00000515253.5
ENST00000507654.5
ENST00000514559.5
ENST00000511791.1
WD repeat domain 41
chr17_+_43398984 0.91 ENST00000320033.5
ADP ribosylation factor like GTPase 4D
chr3_+_191329020 0.90 ENST00000392456.4
coiled-coil domain containing 50
chr20_-_56392131 0.90 ENST00000422322.5
ENST00000371356.6
ENST00000451915.1
ENST00000347343.6
ENST00000395911.5
ENST00000395915.8
ENST00000395907.5
ENST00000441357.5
ENST00000456249.5
ENST00000420474.5
ENST00000395914.5
ENST00000312783.10
ENST00000395913.7
aurora kinase A
chr18_+_54828406 0.90 ENST00000262094.10
RAB27B, member RAS oncogene family
chr4_-_69961007 0.90 ENST00000353151.3
casein beta
chr17_-_66229380 0.89 ENST00000205948.11
apolipoprotein H
chr21_-_30497160 0.88 ENST00000334058.3
keratin associated protein 19-4
chr18_+_657637 0.88 ENST00000323274.15
thymidylate synthetase
chr1_+_192158448 0.87 ENST00000367460.4
regulator of G protein signaling 18
chr4_-_69214743 0.87 ENST00000446444.2
UDP glucuronosyltransferase family 2 member B11
chr14_+_35122722 0.86 ENST00000605870.5
ENST00000557404.3
protein only RNase P catalytic subunit
chr11_+_45921618 0.86 ENST00000529052.5
ENST00000531526.5
LARGE xylosyl- and glucuronyltransferase 2
chr6_+_72216442 0.86 ENST00000425662.6
ENST00000453976.6
regulating synaptic membrane exocytosis 1
chr10_+_5446601 0.84 ENST00000449083.5
ENST00000380359.3
neuroepithelial cell transforming 1
chr19_+_45340760 0.84 ENST00000585434.5
kinesin light chain 3
chr6_-_75206044 0.84 ENST00000322507.13
collagen type XII alpha 1 chain
chr14_-_106593319 0.84 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr11_-_7796942 0.84 ENST00000329434.3
olfactory receptor family 5 subfamily P member 2
chr3_+_189789734 0.83 ENST00000437221.5
ENST00000392463.6
ENST00000392461.7
ENST00000449992.5
ENST00000456148.1
tumor protein p63
chr4_-_159035226 0.82 ENST00000434826.3
chromosome 4 open reading frame 45
chr3_+_189631373 0.82 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr2_+_200585987 0.81 ENST00000374700.7
aldehyde oxidase 1
chr14_-_67412112 0.81 ENST00000216446.9
pleckstrin 2
chr12_+_55931148 0.81 ENST00000549629.5
ENST00000555218.5
ENST00000331886.10
diacylglycerol kinase alpha
chr17_-_48545077 0.81 ENST00000330070.6
homeobox B2
chr9_-_74952904 0.81 ENST00000376854.6
chromosome 9 open reading frame 40
chr3_+_52536593 0.80 ENST00000307106.3
ENST00000477703.6
ENST00000476842.1
small integral membrane protein 4
chr10_+_5196831 0.80 ENST00000263126.3
aldo-keto reductase family 1 member C4
chr10_-_96357155 0.79 ENST00000536387.5
oligodendrocytic myelin paranodal and inner loop protein
chr19_-_53132873 0.79 ENST00000601493.5
ENST00000599261.5
ENST00000597503.5
ENST00000500065.8
ENST00000594011.5
ENST00000595193.5
ENST00000595813.5
ENST00000600574.5
ENST00000596051.1
ENST00000601110.5
ENST00000243643.9
ENST00000421033.5
zinc finger protein 415
chr6_+_106086316 0.79 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr4_+_176319942 0.79 ENST00000503362.2
signal peptidase complex subunit 3
chr6_+_121435595 0.79 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr12_+_80099535 0.79 ENST00000646859.1
ENST00000547103.7
otogelin like
chr9_+_122370523 0.78 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chr11_-_11353241 0.77 ENST00000528848.3
casein kinase 2 alpha 3
chr11_-_13496018 0.77 ENST00000529816.1
parathyroid hormone
chr1_+_155209213 0.77 ENST00000609421.1
metaxin 1
chr11_-_48983826 0.77 ENST00000649162.1
tripartite motif-containing 51G, pseudogene
chr14_+_51489112 0.77 ENST00000356218.8
FERM domain containing 6
chrX_+_30243715 0.77 ENST00000378981.8
ENST00000397550.6
MAGE family member B1
chr11_+_56176618 0.76 ENST00000312298.1
olfactory receptor family 5 subfamily J member 2
chr3_-_156555083 0.76 ENST00000265044.7
ENST00000476217.5
signal sequence receptor subunit 3
chr3_-_48089203 0.76 ENST00000468075.2
ENST00000360240.10
microtubule associated protein 4
chr3_+_155083523 0.76 ENST00000680057.1
membrane metalloendopeptidase
chr19_-_7058640 0.76 ENST00000333843.8
methyl-CpG binding domain protein 3 like 3
chr12_-_7444139 0.76 ENST00000416109.2
ENST00000313599.8
CD163 molecule like 1
chr13_-_30307539 0.75 ENST00000380615.8
katanin catalytic subunit A1 like 1
chr1_+_101237009 0.74 ENST00000305352.7
sphingosine-1-phosphate receptor 1
chr4_+_87832917 0.74 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr3_-_156555135 0.74 ENST00000467789.5
signal sequence receptor subunit 3
chr3_+_189789643 0.74 ENST00000354600.10
tumor protein p63
chr8_+_81280527 0.74 ENST00000297258.11
fatty acid binding protein 5
chr18_+_24460655 0.74 ENST00000426880.2
histamine receptor H4
chr1_+_158831323 0.73 ENST00000368141.5
myeloid cell nuclear differentiation antigen
chr22_-_28712136 0.73 ENST00000464581.6
checkpoint kinase 2
chr2_+_90038848 0.73 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr19_+_926001 0.72 ENST00000263620.8
AT-rich interaction domain 3A
chr18_+_63887698 0.72 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr17_-_35121487 0.72 ENST00000593039.5
RAD51L3-RFFL readthrough
chr9_-_70414657 0.72 ENST00000377126.4
Kruppel like factor 9
chr8_-_63026179 0.71 ENST00000677919.1
gamma-glutamyl hydrolase
chr7_+_16661182 0.71 ENST00000446596.5
ENST00000452975.6
ENST00000438834.5
basic leucine zipper and W2 domains 2
chr1_-_28058087 0.71 ENST00000373864.5
EYA transcriptional coactivator and phosphatase 3
chr2_-_208190001 0.71 ENST00000451346.5
ENST00000341287.9
chromosome 2 open reading frame 80
chr3_-_33645433 0.70 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr14_-_106360320 0.70 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr1_+_154405326 0.70 ENST00000368485.8
interleukin 6 receptor
chr6_+_36678699 0.70 ENST00000405375.5
ENST00000244741.10
ENST00000373711.3
cyclin dependent kinase inhibitor 1A
chr5_+_31193678 0.70 ENST00000265071.3
cadherin 6
chr4_+_85604146 0.70 ENST00000512201.5
Rho GTPase activating protein 24
chr15_-_21718245 0.70 ENST00000630556.1
novel gene identicle to IGHV1OR15-1
chr18_+_24460630 0.69 ENST00000256906.5
histamine receptor H4
chr15_+_69414246 0.69 ENST00000260363.9
ENST00000395392.6
kinesin family member 23
chr5_-_112419251 0.68 ENST00000261486.6
erythrocyte membrane protein band 4.1 like 4A
chr9_-_21351378 0.68 ENST00000380210.1
interferon alpha 6
chr2_+_233691607 0.68 ENST00000373424.5
ENST00000441351.1
UDP glucuronosyltransferase family 1 member A6
chr12_+_21526287 0.68 ENST00000256969.7
spexin hormone
chr5_+_160421847 0.68 ENST00000352433.10
ENST00000517480.1
ENST00000520452.5
ENST00000393964.1
PTTG1 regulator of sister chromatid separation, securin
chr6_-_48111132 0.67 ENST00000398738.3
ENST00000679966.1
ENST00000339488.9
patched domain containing 4
chr7_+_26293025 0.67 ENST00000396376.5
sorting nexin 10
chr1_+_119414931 0.67 ENST00000543831.5
ENST00000433745.5
ENST00000369416.4
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr3_-_185821092 0.67 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chr5_+_141338753 0.67 ENST00000528330.2
ENST00000394576.3
protocadherin gamma subfamily A, 2
chr1_-_149812359 0.67 ENST00000369167.2
ENST00000545683.1
H2B clustered histone 18
chr19_+_54451290 0.66 ENST00000610347.1
leukocyte receptor cluster member 8
chr2_-_101387453 0.66 ENST00000324768.6
cellular repressor of E1A stimulated genes 2
chr21_+_44939992 0.66 ENST00000397826.7
ENST00000458015.1
ENST00000291634.11
family with sequence similarity 207 member A
chr2_-_227164194 0.66 ENST00000396625.5
collagen type IV alpha 4 chain
chr19_-_2783308 0.66 ENST00000677562.1
ENST00000677754.1
small glutamine rich tetratricopeptide repeat containing alpha

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0019858 cytosine metabolic process(GO:0019858)
0.8 2.3 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.7 2.2 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.6 6.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.5 1.6 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.5 2.1 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.5 2.9 GO:0060356 leucine import(GO:0060356)
0.5 1.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.5 3.2 GO:0097338 response to clozapine(GO:0097338)
0.4 1.8 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.4 2.5 GO:0061143 alveolar primary septum development(GO:0061143)
0.4 1.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.4 2.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.3 2.8 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.3 2.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 1.0 GO:0018874 benzoate metabolic process(GO:0018874)
0.3 1.4 GO:0021569 rhombomere 3 development(GO:0021569)
0.3 1.3 GO:0002384 hepatic immune response(GO:0002384)
0.3 2.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3 1.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 0.9 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.3 0.9 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.3 1.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.3 1.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.3 0.3 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.3 2.3 GO:0070995 NADPH oxidation(GO:0070995)
0.3 1.4 GO:0030035 microspike assembly(GO:0030035)
0.3 0.8 GO:0046110 xanthine metabolic process(GO:0046110)
0.3 1.4 GO:0090131 mesenchyme migration(GO:0090131)
0.3 0.8 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.2 0.7 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.2 0.9 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.2 2.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 2.5 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.2 0.6 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.2 0.6 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 0.8 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 1.9 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 3.7 GO:0061029 eyelid development in camera-type eye(GO:0061029) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 2.3 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 1.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 0.8 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 1.7 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.2 0.6 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.2 3.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 1.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.2 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.2 0.4 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.2 2.5 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.2 0.7 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 0.9 GO:0019087 transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860)
0.2 0.7 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 0.5 GO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.2 1.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 0.3 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.2 1.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 1.0 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 0.9 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.2 0.9 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 0.8 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.2 1.8 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 0.9 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.6 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 1.4 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.4 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.8 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 1.4 GO:0060005 vestibular reflex(GO:0060005)
0.1 1.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.4 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.1 0.5 GO:0061056 sclerotome development(GO:0061056)
0.1 0.8 GO:0003383 apical constriction(GO:0003383)
0.1 0.8 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 1.7 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042)
0.1 0.5 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.4 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.9 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.5 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.1 0.3 GO:0009720 detection of hormone stimulus(GO:0009720)
0.1 0.9 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 1.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 1.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.4 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.1 0.3 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.5 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.4 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.1 0.5 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.5 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.1 0.7 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 0.6 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.1 2.0 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.6 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 2.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 2.9 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.3 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.7 GO:0051414 response to cortisol(GO:0051414)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 1.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.3 GO:0007538 primary sex determination(GO:0007538) negative regulation of female gonad development(GO:2000195)
0.1 0.7 GO:1904306 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.1 0.3 GO:0060426 lung vasculature development(GO:0060426)
0.1 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 1.3 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.6 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.1 GO:2000506 negative regulation of energy homeostasis(GO:2000506)
0.1 1.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.2 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.8 GO:0051013 microtubule severing(GO:0051013)
0.1 0.4 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 1.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.1 0.6 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 1.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.7 GO:0000101 sulfur amino acid transport(GO:0000101)
0.1 0.7 GO:0007008 outer mitochondrial membrane organization(GO:0007008)
0.1 0.6 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.9 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1 2.1 GO:0002076 osteoblast development(GO:0002076)
0.1 0.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.3 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 1.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 1.0 GO:0060022 hard palate development(GO:0060022)
0.1 0.1 GO:0070432 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.1 0.3 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.5 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.2 GO:2000452 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.1 0.6 GO:0051026 chiasma assembly(GO:0051026)
0.1 2.7 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.1 0.8 GO:0051451 myoblast migration(GO:0051451)
0.1 2.6 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.5 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 0.2 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.1 0.2 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 1.3 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 0.7 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 0.5 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.6 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.7 GO:0000012 single strand break repair(GO:0000012)
0.1 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.3 GO:0070269 pyroptosis(GO:0070269)
0.1 0.5 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.7 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.3 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.4 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.2 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.7 GO:1903690 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 2.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 1.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.4 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.6 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.2 GO:1902164 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 1.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.6 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 1.5 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:0034255 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.8 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.7 GO:0032196 transposition(GO:0032196)
0.0 0.7 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 1.2 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.4 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.2 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 2.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 1.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.4 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 1.6 GO:0000732 strand displacement(GO:0000732)
0.0 0.2 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 1.0 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 1.4 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.7 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:1903537 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 1.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.0 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 1.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.5 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.5 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.9 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0002881 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880) negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.3 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.5 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.5 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.9 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.5 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.5 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 4.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.4 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 1.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 2.6 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.4 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 2.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.5 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.7 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 2.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.0 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915) immunoglobulin biosynthetic process(GO:0002378) negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 3.4 GO:0045047 protein targeting to ER(GO:0045047)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.1 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.5 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.1 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.2 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 2.5 GO:0070268 cornification(GO:0070268)
0.0 0.5 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 1.6 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.1 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 2.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.8 GO:1901998 toxin transport(GO:1901998)
0.0 0.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.5 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.2 GO:1900409 positive regulation of cellular response to oxidative stress(GO:1900409) positive regulation of oxidative stress-induced cell death(GO:1903209)
0.0 0.1 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.8 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.9 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.2 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 1.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.7 GO:0006953 acute-phase response(GO:0006953)
0.0 0.2 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.5 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0033572 transferrin transport(GO:0033572)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.4 GO:0045576 mast cell activation(GO:0045576)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.2 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.0 0.6 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.5 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.3 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.5 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 0.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 1.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.3 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.6 1.7 GO:0033150 cytoskeletal calyx(GO:0033150)
0.5 1.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.4 1.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.3 1.6 GO:0031523 Myb complex(GO:0031523)
0.3 4.5 GO:0030478 actin cap(GO:0030478)
0.3 1.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 1.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 0.8 GO:0005595 collagen type XII trimer(GO:0005595)
0.2 0.6 GO:0071753 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.2 1.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 2.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 1.1 GO:0097169 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.2 0.5 GO:0000805 X chromosome(GO:0000805) autosome(GO:0030849)
0.2 1.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2 3.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 1.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 2.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.6 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 0.7 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.5 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 1.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.7 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 1.9 GO:0008091 spectrin(GO:0008091)
0.1 0.3 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 2.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.9 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 1.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 1.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.8 GO:0005787 signal peptidase complex(GO:0005787)
0.1 6.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.4 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.7 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.8 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 1.6 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.1 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.1 0.3 GO:0071547 piP-body(GO:0071547)
0.1 2.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.2 GO:0051233 spindle midzone(GO:0051233)
0.1 0.5 GO:0043196 varicosity(GO:0043196)
0.1 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.4 GO:0042627 chylomicron(GO:0042627)
0.1 1.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.3 GO:0043203 axon hillock(GO:0043203)
0.1 0.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0031417 NatC complex(GO:0031417)
0.0 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.6 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 1.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.6 GO:0034464 BBSome(GO:0034464)
0.0 0.9 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.6 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 3.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 3.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.5 GO:0071437 invadopodium(GO:0071437)
0.0 1.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 2.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.0 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 2.7 GO:0043195 terminal bouton(GO:0043195)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.7 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 2.6 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.0 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.5 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 6.1 GO:0001726 ruffle(GO:0001726)
0.0 1.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.8 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.7 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.4 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 1.4 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 2.8 GO:0031968 organelle outer membrane(GO:0031968)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0000930 gamma-tubulin complex(GO:0000930)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.5 2.8 GO:0005499 vitamin D binding(GO:0005499)
0.4 1.3 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.4 3.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.4 1.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.4 1.6 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.4 1.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.3 1.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.3 2.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 1.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.3 0.9 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.2 1.4 GO:1990254 keratin filament binding(GO:1990254)
0.2 0.2 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.2 1.4 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.2 1.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 0.7 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.2 2.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.6 GO:0035375 zymogen binding(GO:0035375)
0.2 0.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.8 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.2 2.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 3.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.5 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 1.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 1.8 GO:0004969 histamine receptor activity(GO:0004969)
0.2 2.0 GO:0042731 PH domain binding(GO:0042731)
0.2 5.0 GO:0005523 tropomyosin binding(GO:0005523)
0.2 0.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 0.5 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 0.3 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.2 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 2.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 0.6 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 0.5 GO:0004056 argininosuccinate lyase activity(GO:0004056)
0.1 0.6 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 1.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 1.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.9 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.5 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 1.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.5 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 1.5 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.5 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 2.5 GO:0051400 BH domain binding(GO:0051400)
0.1 0.6 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1 3.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.6 GO:0042806 fucose binding(GO:0042806)
0.1 1.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.8 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 1.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.9 GO:0043295 glutathione binding(GO:0043295)
0.1 0.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.9 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 1.3 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 4.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.4 GO:0019862 IgA binding(GO:0019862)
0.1 0.3 GO:0034584 piRNA binding(GO:0034584)
0.1 1.3 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 2.7 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 1.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.4 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.4 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 10.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 2.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.2 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.8 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 1.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 2.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.7 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.6 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 2.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.7 GO:0031489 myosin V binding(GO:0031489)
0.1 1.8 GO:0005549 odorant binding(GO:0005549)
0.1 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.0 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.7 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 1.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.7 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.3 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.3 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 1.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.3 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 0.3 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.6 GO:0015266 protein channel activity(GO:0015266)
0.0 0.2 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 2.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 3.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 5.6 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 1.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 9.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.1 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.5 GO:0016918 retinal binding(GO:0016918)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 1.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 3.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0019960 C-X3-C chemokine receptor activity(GO:0016495) C-X3-C chemokine binding(GO:0019960)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 1.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 4.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.7 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 3.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 3.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 1.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 3.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.6 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.6 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.1 3.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.3 ST STAT3 PATHWAY STAT3 Pathway
0.1 4.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 2.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 4.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 3.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 3.2 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 2.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 12.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 2.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 PID ATM PATHWAY ATM pathway
0.0 1.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 2.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 4.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.1 7.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 5.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 3.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 3.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.1 REACTOME KINESINS Genes involved in Kinesins
0.1 1.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 9.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 3.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 2.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.3 REACTOME DEFENSINS Genes involved in Defensins
0.1 1.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 2.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 2.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 5.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 2.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 2.1 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 2.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 1.0 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 2.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 2.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 2.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME G1 PHASE Genes involved in G1 Phase