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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXC11

Z-value: 0.55

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Transcription factors associated with HOXC11

Gene Symbol Gene ID Gene Info
HOXC11
ENSG00000123388.4 HOXC11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC11hg38_v1_chr12_+_53973108_53973140-0.193.2e-01Click!

Activity profile of HOXC11 motif

Sorted Z-values of HOXC11 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC11

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_189179754 2.84 ENST00000374866.9
ENST00000618828.1
COL5A2
collagen type V alpha 2 chain
chr5_+_149141817 1.71 ENST00000504238.5
ABLIM3
actin binding LIM protein family member 3
chr7_+_134779663 1.62 ENST00000361901.6
CALD1
caldesmon 1
chr7_+_134779625 1.59 ENST00000454108.5
ENST00000361675.7
CALD1
caldesmon 1
chr11_+_111245725 1.46 ENST00000280325.7
C11orf53
chromosome 11 open reading frame 53
chrX_-_108439472 1.32 ENST00000372216.8
COL4A6
collagen type IV alpha 6 chain
chr14_-_56805648 1.18 ENST00000554788.5
ENST00000554845.1
ENST00000408990.8
OTX2
orthodenticle homeobox 2
chr2_+_227813834 1.17 ENST00000358813.5
ENST00000409189.7
CCL20
C-C motif chemokine ligand 20
chr7_-_41703062 1.12 ENST00000242208.5
INHBA
inhibin subunit beta A
chr6_+_12290353 1.12 ENST00000379375.6
EDN1
endothelin 1
chr12_-_52385649 1.00 ENST00000257951.3
KRT84
keratin 84
chr15_-_83283449 0.98 ENST00000569704.2
BNC1
basonuclin 1
chr4_+_143433491 0.90 ENST00000512843.1
GAB1
GRB2 associated binding protein 1
chr7_-_93890160 0.90 ENST00000451238.1
TFPI2
tissue factor pathway inhibitor 2
chr12_-_95116967 0.87 ENST00000551521.5
FGD6
FYVE, RhoGEF and PH domain containing 6
chr3_-_37174578 0.83 ENST00000336686.9
LRRFIP2
LRR binding FLII interacting protein 2
chr20_+_59604527 0.82 ENST00000371015.6
PHACTR3
phosphatase and actin regulator 3
chr1_+_209704836 0.81 ENST00000367027.5
HSD11B1
hydroxysteroid 11-beta dehydrogenase 1
chr2_+_209579399 0.79 ENST00000360351.8
MAP2
microtubule associated protein 2
chr2_+_209579598 0.78 ENST00000445941.5
ENST00000673860.1
MAP2
microtubule associated protein 2
chr18_-_12656716 0.77 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
SPIRE1
spire type actin nucleation factor 1
chr2_-_55334529 0.77 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
CCDC88A
coiled-coil domain containing 88A
chr15_+_67125707 0.75 ENST00000540846.6
SMAD3
SMAD family member 3
chr13_+_108596152 0.74 ENST00000356711.7
ENST00000251041.10
MYO16
myosin XVI
chr15_-_55249029 0.72 ENST00000566877.5
RAB27A
RAB27A, member RAS oncogene family
chr1_-_204166334 0.68 ENST00000272190.9
REN
renin
chr1_+_209686173 0.64 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
HSD11B1
hydroxysteroid 11-beta dehydrogenase 1
chr21_-_30497160 0.64 ENST00000334058.3
KRTAP19-4
keratin associated protein 19-4
chr2_+_157257687 0.64 ENST00000259056.5
GALNT5
polypeptide N-acetylgalactosaminyltransferase 5
chr10_+_17229267 0.63 ENST00000224237.9
VIM
vimentin
chr20_-_57710539 0.61 ENST00000395816.7
ENST00000347215.8
PMEPA1
prostate transmembrane protein, androgen induced 1
chr12_+_130162456 0.60 ENST00000539839.1
ENST00000229030.5
FZD10
frizzled class receptor 10
chr1_-_93681829 0.59 ENST00000260502.11
BCAR3
BCAR3 adaptor protein, NSP family member
chr8_+_26577843 0.59 ENST00000311151.9
DPYSL2
dihydropyrimidinase like 2
chr12_+_1691011 0.57 ENST00000357103.5
ADIPOR2
adiponectin receptor 2
chr12_-_27971970 0.54 ENST00000395872.5
ENST00000201015.8
PTHLH
parathyroid hormone like hormone
chr3_+_101827982 0.53 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKBIZ
NFKB inhibitor zeta
chr20_+_44355692 0.51 ENST00000316673.8
ENST00000609795.5
ENST00000457232.5
ENST00000609262.5
HNF4A
hepatocyte nuclear factor 4 alpha
chr14_-_56810448 0.51 ENST00000339475.10
ENST00000555006.5
ENST00000672264.2
ENST00000554559.5
ENST00000555804.1
OTX2
orthodenticle homeobox 2
chr10_-_29736956 0.51 ENST00000674475.1
SVIL
supervillin
chr19_+_926001 0.50 ENST00000263620.8
ARID3A
AT-rich interaction domain 3A
chr9_+_102995308 0.49 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
CYLC2
cylicin 2
chr17_-_43661915 0.49 ENST00000318579.9
ENST00000393661.2
MEOX1
mesenchyme homeobox 1
chr1_-_120054225 0.47 ENST00000602566.6
NOTCH2
notch receptor 2
chr11_-_5516690 0.43 ENST00000380184.2
UBQLNL
ubiquilin like
chr2_+_209579429 0.41 ENST00000361559.8
MAP2
microtubule associated protein 2
chr6_+_31715339 0.40 ENST00000375824.1
ENST00000375825.7
LY6G6D
lymphocyte antigen 6 family member G6D
chr6_+_15246054 0.38 ENST00000341776.7
JARID2
jumonji and AT-rich interaction domain containing 2
chrX_-_132219473 0.37 ENST00000620646.4
RAP2C
RAP2C, member of RAS oncogene family
chr19_-_14090695 0.37 ENST00000533683.7
SAMD1
sterile alpha motif domain containing 1
chrX_-_132219439 0.36 ENST00000370874.2
RAP2C
RAP2C, member of RAS oncogene family
chr19_-_14090963 0.33 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr19_-_19515542 0.29 ENST00000585580.4
TSSK6
testis specific serine kinase 6
chr7_-_81770122 0.29 ENST00000423064.7
HGF
hepatocyte growth factor
chr11_-_11353241 0.28 ENST00000528848.3
CSNK2A3
casein kinase 2 alpha 3
chr11_+_64234569 0.28 ENST00000309422.7
ENST00000426086.3
VEGFB
vascular endothelial growth factor B
chr19_+_35143237 0.28 ENST00000586063.5
ENST00000270310.7
ENST00000588265.1
FXYD7
FXYD domain containing ion transport regulator 7
chr21_+_37367097 0.28 ENST00000644942.1
DYRK1A
dual specificity tyrosine phosphorylation regulated kinase 1A
chr11_+_63838902 0.27 ENST00000377810.8
MARK2
microtubule affinity regulating kinase 2
chr17_+_81395469 0.26 ENST00000584436.7
BAHCC1
BAH domain and coiled-coil containing 1
chr7_-_27165517 0.26 ENST00000396345.1
ENST00000343483.7
HOXA9
homeobox A9
chr19_-_35742431 0.26 ENST00000592537.5
ENST00000246532.6
ENST00000588992.5
IGFLR1
IGF like family receptor 1
chr14_-_56810380 0.26 ENST00000672125.1
ENST00000673481.1
OTX2
orthodenticle homeobox 2
chr17_+_81395449 0.26 ENST00000675386.2
BAHCC1
BAH domain and coiled-coil containing 1
chr5_-_83720813 0.25 ENST00000515590.1
ENST00000274341.9
HAPLN1
hyaluronan and proteoglycan link protein 1
chr18_-_50825373 0.24 ENST00000588444.5
ENST00000256425.6
ENST00000428869.6
MRO
maestro
chr3_-_20012250 0.24 ENST00000389050.5
PP2D1
protein phosphatase 2C like domain containing 1
chr19_+_4402615 0.23 ENST00000301280.10
CHAF1A
chromatin assembly factor 1 subunit A
chr19_-_10309783 0.23 ENST00000403352.1
ENST00000403903.7
ZGLP1
zinc finger GATA like protein 1
chr8_+_69466617 0.23 ENST00000525061.5
ENST00000260128.8
ENST00000458141.6
SULF1
sulfatase 1
chr11_-_31807617 0.23 ENST00000639920.1
ENST00000640460.1
PAX6
paired box 6
chr6_-_137494387 0.23 ENST00000367734.4
OLIG3
oligodendrocyte transcription factor 3
chr5_-_88785493 0.21 ENST00000503554.4
MEF2C
myocyte enhancer factor 2C
chr8_-_21812320 0.21 ENST00000517328.5
GFRA2
GDNF family receptor alpha 2
chr1_-_9069608 0.21 ENST00000377424.9
SLC2A5
solute carrier family 2 member 5
chr1_-_241999091 0.21 ENST00000357246.4
MAP1LC3C
microtubule associated protein 1 light chain 3 gamma
chr8_+_26293112 0.20 ENST00000523925.5
ENST00000315985.7
PPP2R2A
protein phosphatase 2 regulatory subunit Balpha
chr6_+_87344812 0.20 ENST00000388923.5
C6orf163
chromosome 6 open reading frame 163
chr16_-_67944113 0.19 ENST00000264005.10
LCAT
lecithin-cholesterol acyltransferase
chr6_-_104859828 0.19 ENST00000519645.5
ENST00000262903.9
ENST00000369125.6
HACE1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr8_+_76683779 0.19 ENST00000523885.2
ZFHX4
zinc finger homeobox 4
chr1_-_159714581 0.18 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
CRP
C-reactive protein
chr17_-_41489907 0.18 ENST00000328119.11
KRT36
keratin 36
chr7_-_151520080 0.18 ENST00000496004.5
RHEB
Ras homolog, mTORC1 binding
chr17_-_48613468 0.17 ENST00000498634.2
HOXB8
homeobox B8
chr12_-_95790755 0.17 ENST00000343702.9
ENST00000344911.8
NTN4
netrin 4
chr11_+_34642366 0.16 ENST00000532302.1
EHF
ETS homologous factor
chr2_-_50347710 0.16 ENST00000342183.9
ENST00000401710.5
NRXN1
neurexin 1
chr10_+_27532521 0.15 ENST00000683924.1
RAB18
RAB18, member RAS oncogene family
chr21_+_37366744 0.15 ENST00000647188.2
DYRK1A
dual specificity tyrosine phosphorylation regulated kinase 1A
chr16_+_7303245 0.15 ENST00000674626.1
RBFOX1
RNA binding fox-1 homolog 1
chr21_+_37366894 0.15 ENST00000647504.1
DYRK1A
dual specificity tyrosine phosphorylation regulated kinase 1A
chr9_-_122227525 0.14 ENST00000373755.6
ENST00000373754.6
LHX6
LIM homeobox 6
chr7_-_20786879 0.14 ENST00000418710.3
ENST00000617581.4
ENST00000361443.4
SP8
Sp8 transcription factor
chr9_-_122213903 0.14 ENST00000464484.3
LHX6
LIM homeobox 6
chr6_-_43053832 0.14 ENST00000265348.9
ENST00000674134.1
ENST00000674100.1
CUL7
cullin 7
chr5_+_177304571 0.13 ENST00000503853.1
PRELID1
PRELI domain containing 1
chr7_-_81770039 0.13 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
HGF
hepatocyte growth factor
chrX_+_108439779 0.13 ENST00000328300.11
COL4A5
collagen type IV alpha 5 chain
chr7_-_123199960 0.12 ENST00000194130.7
SLC13A1
solute carrier family 13 member 1
chr4_-_99144238 0.12 ENST00000512499.5
ENST00000504125.1
ENST00000505590.5
ENST00000629236.2
ENST00000508393.5
ENST00000265512.12
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr1_+_12464912 0.12 ENST00000543766.2
VPS13D
vacuolar protein sorting 13 homolog D
chr1_-_152159227 0.12 ENST00000316073.3
RPTN
repetin
chr17_+_59940908 0.12 ENST00000591035.1
ENSG00000267318.1
novel protein
chr16_-_2264221 0.12 ENST00000566397.5
RNPS1
RNA binding protein with serine rich domain 1
chr17_-_81918134 0.12 ENST00000328666.11
SIRT7
sirtuin 7
chr21_-_30829755 0.12 ENST00000621162.1
KRTAP7-1
keratin associated protein 7-1
chr1_+_92168915 0.11 ENST00000637221.2
BTBD8
BTB domain containing 8
chr9_-_122213874 0.11 ENST00000482062.1
LHX6
LIM homeobox 6
chr1_+_151766655 0.11 ENST00000400999.7
OAZ3
ornithine decarboxylase antizyme 3
chr3_+_16265330 0.11 ENST00000606098.1
OXNAD1
oxidoreductase NAD binding domain containing 1
chr18_+_32190033 0.11 ENST00000269202.11
MEP1B
meprin A subunit beta
chr12_+_69825221 0.11 ENST00000552032.7
MYRFL
myelin regulatory factor like
chr2_+_210556590 0.11 ENST00000233072.10
ENST00000619804.1
CPS1
carbamoyl-phosphate synthase 1
chr2_-_206159509 0.11 ENST00000423725.5
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1
chrX_+_108439866 0.11 ENST00000361603.7
COL4A5
collagen type IV alpha 5 chain
chr13_-_46052712 0.11 ENST00000242848.8
ENST00000679008.1
ENST00000282007.7
ZC3H13
zinc finger CCCH-type containing 13
chr18_+_32190015 0.11 ENST00000581447.1
MEP1B
meprin A subunit beta
chr6_-_90586883 0.10 ENST00000369325.7
ENST00000369327.7
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr14_-_50561119 0.10 ENST00000555216.5
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr16_-_18896874 0.10 ENST00000565324.5
ENST00000561947.5
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr16_-_21652598 0.10 ENST00000569602.1
ENST00000268389.6
IGSF6
immunoglobulin superfamily member 6
chr12_-_18090141 0.10 ENST00000536890.1
RERGL
RERG like
chrX_+_66164210 0.10 ENST00000343002.7
ENST00000336279.9
HEPH
hephaestin
chr8_+_103819244 0.09 ENST00000262231.14
ENST00000507740.5
ENST00000408894.6
RIMS2
regulating synaptic membrane exocytosis 2
chr6_-_90587018 0.09 ENST00000369332.7
ENST00000369329.8
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr5_-_88823763 0.09 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
MEF2C
myocyte enhancer factor 2C
chr20_+_34977625 0.09 ENST00000618182.6
MYH7B
myosin heavy chain 7B
chr1_-_9069572 0.09 ENST00000377414.7
SLC2A5
solute carrier family 2 member 5
chrX_+_66164340 0.09 ENST00000441993.7
ENST00000419594.6
ENST00000425114.2
HEPH
hephaestin
chr12_-_46825949 0.08 ENST00000547477.5
ENST00000447411.5
ENST00000266579.9
SLC38A4
solute carrier family 38 member 4
chr6_-_136526472 0.08 ENST00000454590.5
ENST00000432797.6
MAP7
microtubule associated protein 7
chr6_-_166168612 0.08 ENST00000296946.6
TBXT
T-box transcription factor T
chr15_+_84981981 0.08 ENST00000339708.9
PDE8A
phosphodiesterase 8A
chr15_+_49423233 0.08 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
FGF7
fibroblast growth factor 7
chr9_+_92974476 0.08 ENST00000337352.10
FGD3
FYVE, RhoGEF and PH domain containing 3
chr1_+_66533575 0.08 ENST00000684751.1
ENST00000683291.1
ENST00000682054.1
ENST00000435165.3
ENST00000684539.1
ENST00000681971.1
ENST00000682476.1
ENST00000684168.1
ENST00000371039.5
SGIP1
SH3GL interacting endocytic adaptor 1
chr12_-_18090185 0.07 ENST00000229002.6
ENST00000538724.6
RERGL
RERG like
chr2_+_27217361 0.07 ENST00000264705.9
ENST00000403525.5
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr8_-_94436926 0.07 ENST00000481490.3
FSBP
fibrinogen silencer binding protein
chr7_-_151519891 0.06 ENST00000262187.10
RHEB
Ras homolog, mTORC1 binding
chr7_-_27152561 0.06 ENST00000467897.2
ENST00000612286.5
ENST00000498652.1
ENSG00000273433.1
HOXA3
ENSG00000272801.1
novel transcript
homeobox A3
novel transcript
chr12_+_69825273 0.06 ENST00000547771.6
MYRFL
myelin regulatory factor like
chr6_+_151690492 0.06 ENST00000404742.5
ENST00000440973.5
ESR1
estrogen receptor 1
chr2_-_50347789 0.06 ENST00000628364.2
NRXN1
neurexin 1
chr4_+_113292925 0.06 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ANK2
ankyrin 2
chr2_-_51032151 0.05 ENST00000628515.2
NRXN1
neurexin 1
chr15_+_84981834 0.05 ENST00000394553.6
PDE8A
phosphodiesterase 8A
chrX_-_134658450 0.05 ENST00000359237.9
PLAC1
placenta enriched 1
chr4_+_113292838 0.05 ENST00000672411.1
ENST00000673231.1
ANK2
ankyrin 2
chr15_-_43879835 0.05 ENST00000636859.1
FRMD5
FERM domain containing 5
chr8_+_133191029 0.04 ENST00000250160.11
CCN4
cellular communication network factor 4
chr2_-_51032091 0.04 ENST00000637511.1
ENST00000405472.7
ENST00000405581.3
ENST00000401669.7
NRXN1
neurexin 1
chr8_-_18808837 0.04 ENST00000286485.12
PSD3
pleckstrin and Sec7 domain containing 3
chr7_-_75772172 0.04 ENST00000005180.9
CCL26
C-C motif chemokine ligand 26
chr5_-_83673544 0.03 ENST00000503117.1
ENST00000510978.5
HAPLN1
hyaluronan and proteoglycan link protein 1
chr6_-_166168700 0.03 ENST00000366871.7
TBXT
T-box transcription factor T
chr7_-_126533850 0.03 ENST00000444921.3
GRM8
glutamate metabotropic receptor 8
chr7_+_22727147 0.03 ENST00000426291.5
ENST00000401651.5
ENST00000258743.10
ENST00000407492.5
ENST00000401630.7
ENST00000406575.1
IL6
interleukin 6
chr4_-_84499281 0.03 ENST00000295886.5
NKX6-1
NK6 homeobox 1
chr1_+_75134382 0.02 ENST00000356261.4
LHX8
LIM homeobox 8
chr19_-_51082883 0.02 ENST00000650543.2
KLK14
kallikrein related peptidase 14
chr1_-_31919093 0.02 ENST00000602683.5
ENST00000470404.5
PTP4A2
protein tyrosine phosphatase 4A2
chr9_+_79573162 0.02 ENST00000425506.5
TLE4
TLE family member 4, transcriptional corepressor
chr13_-_103066411 0.02 ENST00000245312.5
SLC10A2
solute carrier family 10 member 2
chr1_+_23019415 0.01 ENST00000465864.2
ENST00000356634.7
ENST00000400181.9
KDM1A
lysine demethylase 1A
chr19_-_39433703 0.01 ENST00000602153.5
RPS16
ribosomal protein S16
chr10_+_61901678 0.01 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
ARID5B
AT-rich interaction domain 5B
chrX_+_105948429 0.01 ENST00000540278.1
NRK
Nik related kinase
chr12_-_70754631 0.01 ENST00000440835.6
ENST00000549308.5
ENST00000550661.1
ENST00000378778.5
PTPRR
protein tyrosine phosphatase receptor type R
chr19_+_35545681 0.00 ENST00000392205.2
TMEM147
transmembrane protein 147
chr2_-_165203870 0.00 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
SCN3A
sodium voltage-gated channel alpha subunit 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 1.2 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.4 1.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.4 1.1 GO:0030185 nitric oxide transport(GO:0030185)
0.1 1.9 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.7 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.7 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.5 GO:0061056 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.1 0.8 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 0.7 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.6 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.0 GO:0035878 nail development(GO:0035878)
0.1 1.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.2 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.1 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.6 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.2 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.2 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.3 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0015847 putrescine transport(GO:0015847)
0.0 0.1 GO:1903717 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.9 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.2 GO:0015755 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.9 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.3 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.5 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.6 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.5 GO:0002076 osteoblast development(GO:0002076)
0.0 2.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.6 GO:0030574 collagen catabolic process(GO:0030574)
0.0 1.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.4 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 1.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 2.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 3.2 GO:0030478 actin cap(GO:0030478)
0.2 1.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 0.5 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 2.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.4 1.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 0.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 0.6 GO:0055100 adiponectin binding(GO:0055100)
0.2 1.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 3.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.6 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 2.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.5 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 5.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0033265 choline binding(GO:0033265)
0.0 0.2 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.0 0.8 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.8 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.8 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.8 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0035276 ethanol binding(GO:0035276)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 3.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 4.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)