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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXC12_HOXD12

Z-value: 0.96

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Transcription factors associated with HOXC12_HOXD12

Gene Symbol Gene ID Gene Info
ENSG00000123407.4 HOXC12
ENSG00000170178.7 HOXD12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD12hg38_v1_chr2_+_176099787_176099812-0.579.3e-04Click!
HOXC12hg38_v1_chr12_+_53954870_53954912-0.222.5e-01Click!

Activity profile of HOXC12_HOXD12 motif

Sorted Z-values of HOXC12_HOXD12 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC12_HOXD12

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_55166632 6.22 ENST00000532817.5
ENST00000527223.6
ENST00000391720.8
dynein axonemal assembly factor 3
chr19_-_55166671 3.88 ENST00000455045.5
dynein axonemal assembly factor 3
chr4_-_16083695 3.83 ENST00000510224.5
prominin 1
chr4_-_16083714 3.80 ENST00000508167.5
prominin 1
chr3_-_19934189 3.76 ENST00000295824.14
EF-hand domain family member B
chr3_+_63652663 3.50 ENST00000343837.8
ENST00000469440.5
sentan, cilia apical structure protein
chr13_-_28718921 3.08 ENST00000266943.11
ENST00000380814.4
solute carrier family 46 member 3
chr9_-_4300049 2.57 ENST00000381971.8
GLIS family zinc finger 3
chr12_-_71157872 2.52 ENST00000546561.2
tetraspanin 8
chr6_+_33080445 2.44 ENST00000428835.5
major histocompatibility complex, class II, DP beta 1
chr6_-_31714062 2.42 ENST00000409239.5
lymphocyte antigen 6 family member G6E
chrY_+_2841864 2.39 ENST00000430575.1
ribosomal protein S4 Y-linked 1
chr1_+_47023659 2.34 ENST00000371901.4
cytochrome P450 family 4 subfamily X member 1
chr12_-_71157992 2.27 ENST00000247829.8
tetraspanin 8
chr6_+_87407965 2.09 ENST00000369562.9
cilia and flagella associated protein 206
chr15_+_70892809 1.97 ENST00000260382.10
ENST00000560755.5
leucine rich repeat containing 49
chr17_+_11598456 1.92 ENST00000579828.5
ENST00000262442.9
ENST00000454412.6
dynein axonemal heavy chain 9
chr8_-_109680812 1.83 ENST00000528716.5
ENST00000527600.5
ENST00000531230.5
ENST00000532189.5
ENST00000534184.5
ENST00000408889.7
ENST00000533171.5
syntabulin
chr7_+_90709816 1.69 ENST00000436577.3
cyclin dependent kinase 14
chr11_-_107457801 1.69 ENST00000282251.9
CWF19 like cell cycle control factor 2
chr9_-_86947496 1.68 ENST00000298743.9
growth arrest specific 1
chr15_+_81134257 1.66 ENST00000286732.5
cilia and flagella associated protein 161
chr5_+_140875299 1.56 ENST00000613593.1
ENST00000398631.3
protocadherin alpha 12
chr17_-_7329266 1.55 ENST00000571887.5
ENST00000315614.11
ENST00000399464.7
ENST00000570460.5
neuralized E3 ubiquitin protein ligase 4
chr6_-_49713521 1.54 ENST00000339139.5
cysteine rich secretory protein 2
chr5_-_55173173 1.53 ENST00000296733.5
ENST00000322374.10
ENST00000381375.7
cell division cycle 20B
chr3_-_172523460 1.51 ENST00000420541.6
TNF superfamily member 10
chr1_-_246507237 1.50 ENST00000490107.6
SET and MYND domain containing 3
chr3_+_32695535 1.47 ENST00000454516.7
CCR4-NOT transcription complex subunit 10
chr8_-_33513077 1.43 ENST00000360742.9
ENST00000523305.1
ENST00000431156.7
ENST00000613904.1
TELO2 interacting protein 2
chr7_+_139133744 1.42 ENST00000430935.5
ENST00000495038.5
ENST00000474035.6
ENST00000478836.6
ENST00000464848.5
ENST00000343187.8
tetratricopeptide repeat domain 26
chr11_+_72189528 1.40 ENST00000312293.9
folate receptor alpha
chr7_+_152759744 1.40 ENST00000377776.7
ENST00000256001.13
ENST00000397282.2
actin related protein 3B
chr10_-_46046264 1.38 ENST00000581478.5
ENST00000582163.3
microseminoprotein beta
chr22_+_28772664 1.31 ENST00000448492.6
ENST00000421503.6
ENST00000249064.9
ENST00000444523.1
coiled-coil domain containing 117
chr2_+_38875962 1.30 ENST00000340556.11
ENST00000410014.5
ENST00000644631.3
ENST00000409665.5
ENST00000409077.2
ENST00000409131.2
MORN repeat containing 2
chr1_+_63523490 1.30 ENST00000371088.5
EF-hand calcium binding domain 7
chr2_-_73233206 1.27 ENST00000258083.3
protease associated domain containing 1
chr8_-_143617457 1.26 ENST00000529048.5
ENST00000529064.5
GDP-L-fucose synthase
chr4_-_1208825 1.25 ENST00000511679.5
ENST00000617421.4
spondin 2
chr5_+_160229499 1.24 ENST00000402432.4
fatty acid binding protein 6
chr8_-_143617498 1.24 ENST00000425753.7
GDP-L-fucose synthase
chr10_-_25016105 1.22 ENST00000376363.5
ENST00000331161.9
enkurin, TRPC channel interacting protein
chr17_-_29930062 1.17 ENST00000579954.1
ENST00000269033.7
ENST00000540801.6
ENST00000590153.1
ENST00000582084.1
slingshot protein phosphatase 2
chr19_-_21836164 1.16 ENST00000354959.9
ENST00000599906.5
zinc finger protein 43
chr2_-_159798043 1.16 ENST00000664982.1
ENST00000259053.6
novel transcript, sense intronic to CD302and LY75-CD302
CD302 molecule
chr5_-_77087245 1.12 ENST00000255198.3
zinc finger BED-type containing 3
chr6_-_49713564 1.12 ENST00000616725.4
ENST00000618917.4
cysteine rich secretory protein 2
chr2_+_137964446 1.11 ENST00000280096.5
ENST00000280097.5
histamine N-methyltransferase
chr5_+_140834230 1.09 ENST00000356878.5
ENST00000525929.2
protocadherin alpha 7
chr14_-_39432414 1.09 ENST00000554932.1
ENST00000298097.7
F-box protein 33
chr2_+_55519610 1.06 ENST00000406691.7
ENST00000407816.7
ENST00000349456.9
ENST00000403007.4
cilia and flagella associated protein 36
chr10_-_50623897 1.06 ENST00000361781.7
ENST00000429490.5
ENST00000619438.4
sphingomyelin synthase 1
chr2_+_169479445 1.06 ENST00000513963.1
ENST00000392663.6
ENST00000295240.8
novel protein
Bardet-Biedl syndrome 5
chr18_-_55588184 1.05 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
transcription factor 4
chr7_+_150368189 1.04 ENST00000519397.1
ENST00000479668.5
replication initiator 1
chr18_-_55587335 1.04 ENST00000638154.3
transcription factor 4
chrX_-_78327626 1.03 ENST00000614798.1
cysteinyl leukotriene receptor 1
chrX_-_78327604 1.02 ENST00000373304.4
cysteinyl leukotriene receptor 1
chr19_+_21082224 1.02 ENST00000620627.1
zinc finger protein 714
chr9_+_135087652 1.01 ENST00000371793.8
ENST00000539529.5
ENST00000392991.8
olfactomedin 1
chr11_+_101914997 1.01 ENST00000263468.13
centrosomal protein 126
chr4_+_153222402 1.00 ENST00000676335.1
ENST00000675146.1
tripartite motif containing 2
chr6_-_79537423 0.99 ENST00000369846.9
ENST00000392959.5
ENST00000467898.3
lebercilin LCA5
chr8_+_75539862 0.98 ENST00000396423.4
hepatocyte nuclear factor 4 gamma
chr1_+_171090892 0.97 ENST00000367755.9
ENST00000479749.1
flavin containing dimethylaniline monoxygenase 3
chr3_-_172523423 0.96 ENST00000241261.7
TNF superfamily member 10
chr18_-_55585773 0.95 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
transcription factor 4
chr6_+_32844789 0.92 ENST00000414474.5
proteasome 20S subunit beta 9
chr3_+_41200080 0.91 ENST00000644524.1
catenin beta 1
chr1_+_100352451 0.88 ENST00000361544.11
ENST00000370124.8
ENST00000336454.5
cell division cycle 14A
chr19_+_20923222 0.88 ENST00000597314.5
ENST00000328178.13
ENST00000601924.5
zinc finger protein 85
chr18_-_55586092 0.88 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
transcription factor 4
chr8_+_75539893 0.87 ENST00000674002.1
hepatocyte nuclear factor 4 gamma
chr18_-_21703688 0.85 ENST00000584464.1
ENST00000578270.5
abhydrolase domain containing 3, phospholipase
chr4_+_112297341 0.85 ENST00000504176.6
ENST00000650871.1
ENST00000177648.13
ENST00000458497.6
alpha kinase 1
chr3_+_41200104 0.85 ENST00000643297.1
ENST00000450969.6
catenin beta 1
chr9_+_2110354 0.85 ENST00000634772.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_68815991 0.82 ENST00000265403.12
ENST00000458688.2
UDP glucuronosyltransferase family 2 member B10
chr4_-_109801978 0.82 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
complement factor I
novel protein
chr1_-_216805367 0.80 ENST00000360012.7
estrogen related receptor gamma
chr22_+_38656627 0.79 ENST00000411557.5
ENST00000396811.6
ENST00000216029.7
ENST00000416285.5
chibby family member 1, beta catenin antagonist
chr17_-_36534927 0.75 ENST00000610930.4
myosin XIX
chr9_-_122213903 0.74 ENST00000464484.3
LIM homeobox 6
chr11_-_5249836 0.73 ENST00000632727.1
ENST00000330597.5
hemoglobin subunit gamma 1
chr8_+_106726012 0.72 ENST00000449762.6
ENST00000297447.10
oxidation resistance 1
chr8_+_2045058 0.72 ENST00000523438.1
myomesin 2
chr3_-_52770856 0.71 ENST00000461689.5
ENST00000535191.5
ENST00000383721.8
ENST00000233027.10
NIMA related kinase 4
chr4_-_155376935 0.71 ENST00000311277.9
microtubule associated protein 9
chr16_+_8642375 0.71 ENST00000562973.1
methyltransferase like 22
chr8_-_79767462 0.69 ENST00000674295.1
ENST00000518733.1
ENST00000674418.1
ENST00000674358.1
ENST00000354724.8
hes related family bHLH transcription factor with YRPW motif 1
chr14_-_35121950 0.68 ENST00000554361.5
ENST00000261475.10
protein phosphatase 2 regulatory subunit B''gamma
chr14_-_67533720 0.68 ENST00000554278.6
transmembrane protein 229B
chr5_-_147453888 0.67 ENST00000398514.7
dihydropyrimidinase like 3
chr1_-_85708382 0.67 ENST00000370574.4
ENST00000431532.6
zinc finger HIT-type containing 6
chr11_-_8810635 0.66 ENST00000527510.5
ENST00000528527.5
ENST00000313726.11
ENST00000528523.5
DENN domain containing 2B
chr19_-_21767560 0.66 ENST00000358296.11
zinc finger protein 100
chr11_+_7597182 0.65 ENST00000528883.5
PPFIA binding protein 2
chr8_+_2045037 0.62 ENST00000262113.9
myomesin 2
chr12_+_108131740 0.62 ENST00000332082.8
WSC domain containing 2
chr3_-_179604628 0.61 ENST00000476781.6
ENST00000259038.6
mitochondrial ribosomal protein L47
chr11_-_67508091 0.60 ENST00000531506.1
cyclin dependent kinase 2 associated protein 2
chr11_-_26572102 0.60 ENST00000455601.6
mucin 15, cell surface associated
chr7_+_138460238 0.58 ENST00000343526.9
tripartite motif containing 24
chr4_-_94342826 0.58 ENST00000295256.10
hematopoietic prostaglandin D synthase
chr11_-_26572130 0.57 ENST00000527569.1
mucin 15, cell surface associated
chr16_+_16390834 0.57 ENST00000344087.4
nuclear pore complex interacting protein family member A7
chr19_+_48993525 0.57 ENST00000601968.5
ENST00000596837.5
RuvB like AAA ATPase 2
chr19_+_48993864 0.55 ENST00000595090.6
RuvB like AAA ATPase 2
chr10_-_112183698 0.54 ENST00000369425.5
ENST00000348367.9
glycerol-3-phosphate acyltransferase, mitochondrial
chr3_-_179604648 0.54 ENST00000392659.2
mitochondrial ribosomal protein L47
chr19_+_21082190 0.53 ENST00000618422.1
ENST00000618008.4
ENST00000425625.5
ENST00000456283.7
zinc finger protein 714
chr2_-_70248598 0.52 ENST00000445587.5
ENST00000433529.7
ENST00000415783.6
TIA1 cytotoxic granule associated RNA binding protein
chr19_-_19733091 0.52 ENST00000344099.4
zinc finger protein 14
chr10_+_24466487 0.51 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr5_+_141135199 0.50 ENST00000231134.8
ENST00000623915.1
protocadherin beta 5
chr19_-_11346486 0.50 ENST00000590482.5
transmembrane protein 205
chr7_+_65373799 0.50 ENST00000357512.3
zinc finger protein 92
chr7_+_74650224 0.49 ENST00000652150.1
ENST00000650807.1
general transcription factor IIi
chr1_+_171781635 0.49 ENST00000361735.4
ENST00000362019.7
ENST00000367737.9
eEF1A lysine and N-terminal methyltransferase
chr19_-_12551426 0.48 ENST00000416136.1
ENST00000339282.12
ENST00000596193.1
ENST00000428311.1
zinc finger protein 564
novel zinc finger protein
chr12_+_14803649 0.48 ENST00000330828.3
chromosome 12 open reading frame 60
chr16_+_20806698 0.47 ENST00000564274.5
ENST00000563068.1
RNA exonuclease 5
chr11_-_5154757 0.47 ENST00000380367.3
olfactory receptor family 52 subfamily A member 1
chr16_-_12803785 0.46 ENST00000433677.6
ENST00000261660.4
ENST00000381774.9
calcineurin like phosphoesterase domain containing 1
chr7_-_78771265 0.46 ENST00000630991.2
ENST00000629359.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr12_-_101830926 0.46 ENST00000299314.12
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
chr12_+_4649097 0.46 ENST00000648836.1
ENST00000266544.10
novel protein
NADH:ubiquinone oxidoreductase subunit A9
chr19_-_11346406 0.45 ENST00000587948.5
transmembrane protein 205
chr12_-_14961256 0.45 ENST00000541380.5
Rho GDP dissociation inhibitor beta
chr12_-_14961559 0.45 ENST00000228945.9
ENST00000541546.5
Rho GDP dissociation inhibitor beta
chr1_+_159005953 0.44 ENST00000426592.6
interferon gamma inducible protein 16
chr17_-_36534841 0.44 ENST00000614623.5
ENST00000621344.4
myosin XIX
chr11_-_796185 0.44 ENST00000533385.5
ENST00000528936.5
ENST00000629634.2
ENST00000625752.2
ENST00000528606.5
ENST00000320230.9
solute carrier family 25 member 22
chr20_-_21397513 0.44 ENST00000351817.5
NK2 homeobox 4
chr17_+_36534980 0.43 ENST00000614443.2
ENST00000619326.1
phosphatidylinositol glycan anchor biosynthesis class W
chr5_+_94618653 0.43 ENST00000265140.10
ENST00000504099.5
SMC5-SMC6 complex localization factor 1
chr10_+_73110375 0.43 ENST00000617744.4
ENST00000544879.5
ENST00000537969.5
ENST00000357321.9
ENST00000349051.9
nudix hydrolase 13
chr19_-_11346228 0.42 ENST00000588560.5
ENST00000592952.5
transmembrane protein 205
chr14_+_55027576 0.41 ENST00000339298.2
suppressor of cytokine signaling 4
chr17_+_36535488 0.41 ENST00000620233.1
phosphatidylinositol glycan anchor biosynthesis class W
chr19_-_37594746 0.41 ENST00000593133.5
ENST00000590751.5
ENST00000358744.3
ENST00000328550.6
ENST00000451802.7
zinc finger protein 571
chr8_+_17027230 0.41 ENST00000318063.10
mitochondrial calcium uptake family member 3
chr19_-_44401575 0.40 ENST00000591679.5
ENST00000544719.6
ENST00000614994.5
ENST00000585868.1
ENST00000588212.1
zinc finger protein 285
novel protein
chr12_-_14961610 0.40 ENST00000542276.1
Rho GDP dissociation inhibitor beta
chr7_+_65373839 0.40 ENST00000431504.1
ENST00000328747.12
zinc finger protein 92
chr14_-_70359630 0.40 ENST00000389912.7
cytochrome c oxidase assembly factor COX16
chr17_-_41440983 0.40 ENST00000246646.4
keratin 38
chr12_+_104215772 0.39 ENST00000429002.6
ENST00000525566.6
thioredoxin reductase 1
chr8_-_42207557 0.39 ENST00000220809.9
ENST00000429089.6
ENST00000519510.5
ENST00000429710.6
ENST00000524009.5
plasminogen activator, tissue type
chr1_-_154608705 0.39 ENST00000649749.1
ENST00000648871.1
adenosine deaminase RNA specific
chr4_+_70028452 0.39 ENST00000530128.5
ENST00000381057.3
ENST00000673563.1
histatin 3
chr10_-_68527498 0.38 ENST00000609923.6
solute carrier family 25 member 16
chr22_-_20320009 0.38 ENST00000405465.3
ENST00000248879.8
DiGeorge syndrome critical region gene 6 like
chr19_-_11346196 0.37 ENST00000586218.5
transmembrane protein 205
chr8_-_42207667 0.37 ENST00000352041.7
ENST00000679151.1
ENST00000679300.1
plasminogen activator, tissue type
chr14_+_73167829 0.36 ENST00000406768.1
presenilin 1
chr7_+_138460400 0.36 ENST00000415680.6
tripartite motif containing 24
chr11_+_112025367 0.35 ENST00000679614.1
ENST00000679878.1
ENST00000280346.11
ENST00000681339.1
ENST00000681328.1
ENST00000681316.1
ENST00000531306.2
ENST00000680331.1
ENST00000393051.5
dihydrolipoamide S-acetyltransferase
chr9_+_131190119 0.35 ENST00000483497.6
nucleoporin 214
chr19_-_45424364 0.35 ENST00000589165.5
ERCC excision repair 1, endonuclease non-catalytic subunit
chr1_+_147242654 0.34 ENST00000652587.1
ENST00000361293.10
ENST00000369258.8
ENST00000369259.4
ENST00000650714.1
ENST00000639534.1
chromodomain helicase DNA binding protein 1 like
chr1_+_239386556 0.34 ENST00000676153.1
cholinergic receptor muscarinic 3
chr15_+_75347030 0.34 ENST00000566313.5
ENST00000355059.9
ENST00000568059.1
ENST00000568881.1
nei like DNA glycosylase 1
chr12_+_69239560 0.33 ENST00000435070.7
cleavage and polyadenylation specific factor 6
chr6_-_166382972 0.33 ENST00000341756.10
ENST00000621630.1
ENST00000621685.4
mitochondrial pyruvate carrier 1
chrX_+_49162564 0.33 ENST00000616266.4
MAGI family member, X-linked
chr1_+_153658687 0.32 ENST00000368685.6
SNAP associated protein
chr7_+_65373873 0.32 ENST00000450302.2
zinc finger protein 92
chr14_+_23306958 0.32 ENST00000554635.1
ENST00000557008.2
BCL2 like 2
BCL2L2-PABPN1 readthrough
chr12_-_91179355 0.32 ENST00000550563.5
ENST00000546370.5
decorin
chr19_-_23758877 0.32 ENST00000402377.3
zinc finger protein 681
chr3_-_25664877 0.31 ENST00000264331.9
ENST00000424225.1
DNA topoisomerase II beta
chr3_-_71360753 0.31 ENST00000648783.1
forkhead box P1
chr1_-_23559490 0.30 ENST00000374561.6
inhibitor of DNA binding 3, HLH protein
chr6_+_30328889 0.30 ENST00000396547.5
ENST00000623385.3
tripartite motif containing 39
TRIM39-RPP21 readthrough
chr15_+_66505289 0.30 ENST00000565627.5
ENST00000564179.5
ENST00000307897.10
zwilch kinetochore protein
chr15_+_76931704 0.30 ENST00000320963.9
ENST00000394885.8
ENST00000394883.3
reticulocalbin 2
chr10_-_127892930 0.30 ENST00000368671.4
clarin 3
chr15_+_66504959 0.29 ENST00000535141.6
ENST00000613446.4
ENST00000446801.6
zwilch kinetochore protein
chr19_-_48249841 0.29 ENST00000447740.6
caspase recruitment domain family member 8
chr8_-_77000070 0.29 ENST00000357039.9
peroxisomal biogenesis factor 2
chr14_-_25010604 0.29 ENST00000550887.5
syntaxin binding protein 6
chr10_-_27242068 0.29 ENST00000375901.5
ENST00000412279.1
ENST00000676731.1
ENST00000679220.1
ENST00000678392.1
ENST00000678446.1
ENST00000677441.1
ENST00000375905.8
acyl-CoA binding domain containing 5
chr7_+_144048948 0.29 ENST00000641693.1
olfactory receptor family 2 subfamily A member 5
chr6_-_106325616 0.28 ENST00000360666.6
autophagy related 5
chr2_+_200889411 0.28 ENST00000409357.5
ENST00000409129.2
NGG1 interacting factor 3 like 1
chr11_+_123902167 0.28 ENST00000641687.1
olfactory receptor family 8 subfamily D member 4
chr3_-_17742498 0.28 ENST00000429383.8
ENST00000446863.5
ENST00000414349.5
ENST00000428355.5
ENST00000425944.5
ENST00000445294.5
ENST00000444471.5
ENST00000415814.6
TBC1 domain family member 5
chr4_-_83284752 0.28 ENST00000311461.7
ENST00000647002.2
ENST00000311469.9
coenzyme Q2, polyprenyltransferase
chr1_+_248509536 0.27 ENST00000641501.1
olfactory receptor family 2 subfamily G member 6
chr6_-_166382927 0.27 ENST00000360961.11
mitochondrial pyruvate carrier 1
chr2_+_200889327 0.27 ENST00000426253.5
ENST00000454952.1
ENST00000651500.1
ENST00000409020.6
ENST00000359683.8
NGG1 interacting factor 3 like 1
chr17_-_36534883 0.27 ENST00000620640.4
myosin XIX
chr1_+_15617415 0.27 ENST00000480945.6
DNA damage inducible 1 homolog 2
chr7_-_38249572 0.26 ENST00000436911.6
T cell receptor gamma constant 2
chr19_-_48255863 0.25 ENST00000522889.5
ENST00000519940.6
ENST00000520753.5
ENST00000519332.5
ENST00000521437.1
ENST00000520007.5
ENST00000651546.1
ENST00000521613.5
caspase recruitment domain family member 8
chr8_+_106726115 0.25 ENST00000521592.5
oxidation resistance 1
chr6_-_8102481 0.25 ENST00000502429.5
ENST00000429723.6
ENST00000379715.10
ENST00000507463.1
eukaryotic translation elongation factor 1 epsilon 1
chr13_-_78659124 0.24 ENST00000282003.7
ORC ubiquitin ligase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.6 GO:2000768 positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.5 1.4 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.3 11.2 GO:0044458 motile cilium assembly(GO:0044458)
0.3 1.8 GO:0007403 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.2 1.9 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 0.7 GO:0061027 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
0.2 1.1 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 1.3 GO:0071461 cellular response to redox state(GO:0071461)
0.2 1.1 GO:0001692 histamine metabolic process(GO:0001692)
0.2 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 1.0 GO:0003190 atrioventricular valve formation(GO:0003190)
0.2 1.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.9 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 1.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.6 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 1.7 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 1.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.4 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.3 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 0.4 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.1 2.5 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 0.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.7 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.6 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.7 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.4 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.3 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.1 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.7 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.1 0.4 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.2 GO:2000395 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 4.7 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 3.9 GO:0003341 cilium movement(GO:0003341)
0.1 1.1 GO:0001302 replicative cell aging(GO:0001302)
0.1 1.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.7 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.3 GO:0002005 angiotensin catabolic process in blood(GO:0002005) angiotensin-mediated drinking behavior(GO:0003051)
0.0 1.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.5 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.3 GO:0035973 aggrephagy(GO:0035973)
0.0 0.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.4 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.2 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 1.5 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 1.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.7 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.6 GO:0015671 oxygen transport(GO:0015671)
0.0 1.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 1.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 2.0 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 1.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 6.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.3 GO:0030903 notochord development(GO:0030903)
0.0 1.8 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.3 GO:0032625 interleukin-21 production(GO:0032625) macrophage colony-stimulating factor production(GO:0036301) interleukin-21 secretion(GO:0072619) regulation of macrophage colony-stimulating factor production(GO:1901256)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.9 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.3 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 0.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.2 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 2.0 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.4 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 1.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.9 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 2.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0019376 galactolipid catabolic process(GO:0019376)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 1.0 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.3 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.4 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0001534 radial spoke(GO:0001534) axonemal outer doublet(GO:0097545)
0.4 7.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 1.8 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.2 1.7 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 0.9 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.6 GO:1990423 RZZ complex(GO:1990423)
0.1 2.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.8 GO:0097433 dense body(GO:0097433)
0.1 0.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.1 GO:0097255 R2TP complex(GO:0097255)
0.1 0.7 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 1.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 1.0 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.0 GO:0060091 kinocilium(GO:0060091)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 1.1 GO:0034464 BBSome(GO:0034464)
0.1 1.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.7 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 2.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 1.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.5 GO:0042382 paraspeckles(GO:0042382)
0.0 1.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.6 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 2.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.9 GO:0030286 dynein complex(GO:0030286)
0.0 1.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 1.0 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 4.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.8 GO:0097546 ciliary base(GO:0097546)
0.0 1.5 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 1.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 6.1 GO:0005929 cilium(GO:0005929)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0061714 folic acid receptor activity(GO:0061714)
0.3 2.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.3 0.9 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.3 1.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 3.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 0.7 GO:0035939 microsatellite binding(GO:0035939)
0.2 1.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 1.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 1.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 1.5 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 1.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.4 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.3 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.9 GO:0034056 estrogen response element binding(GO:0034056)
0.1 8.3 GO:0042805 actinin binding(GO:0042805)
0.1 0.3 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.8 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.4 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 1.0 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 1.8 GO:0070411 I-SMAD binding(GO:0070411)
0.1 2.1 GO:0070330 aromatase activity(GO:0070330)
0.1 1.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.4 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 2.4 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.8 GO:0032052 bile acid binding(GO:0032052)
0.0 1.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 2.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 1.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.5 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 1.0 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 5.0 GO:0005178 integrin binding(GO:0005178)
0.0 1.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.5 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.8 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.4 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 2.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 3.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 1.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.1 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.0 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 2.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 5.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.9 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER