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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXD10

Z-value: 0.64

Motif logo

Transcription factors associated with HOXD10

Gene Symbol Gene ID Gene Info
ENSG00000128710.6 HOXD10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD10hg38_v1_chr2_+_176116768_176116794-0.096.4e-01Click!

Activity profile of HOXD10 motif

Sorted Z-values of HOXD10 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD10

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_47981535 1.03 ENST00000402813.9
cyclic nucleotide gated channel subunit alpha 1
chr4_-_67883987 0.88 ENST00000283916.11
transmembrane serine protease 11D
chr5_+_96875978 0.75 ENST00000510373.5
endoplasmic reticulum aminopeptidase 2
chr18_+_63777773 0.74 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr15_-_28174423 0.65 ENST00000569772.1
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr12_-_13095664 0.64 ENST00000337630.10
ENST00000545699.1
germ cell associated 1
chr18_+_31447732 0.60 ENST00000257189.5
desmoglein 3
chr1_-_94925759 0.59 ENST00000415017.1
ENST00000545882.5
calponin 3
chr13_+_77535742 0.57 ENST00000377246.7
sciellin
chr13_+_77535681 0.57 ENST00000349847.4
sciellin
chr13_+_77535669 0.57 ENST00000535157.5
sciellin
chr4_+_186227501 0.52 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
kallikrein B1
chr2_-_29074515 0.49 ENST00000331664.6
photoreceptor cilium actin regulator
chr5_-_135954962 0.49 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
leukocyte cell derived chemotaxin 2
chr10_-_77140757 0.48 ENST00000637862.2
potassium calcium-activated channel subfamily M alpha 1
chr10_-_89207306 0.47 ENST00000371852.4
cholesterol 25-hydroxylase
chr2_-_29223808 0.47 ENST00000642122.1
ALK receptor tyrosine kinase
chr4_-_76007501 0.46 ENST00000264888.6
C-X-C motif chemokine ligand 9
chrX_-_154371210 0.45 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr6_+_37929959 0.44 ENST00000373389.5
zinc finger AN1-type containing 3
chr12_+_8157034 0.44 ENST00000396570.7
zinc finger protein 705A
chr12_+_20810698 0.44 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr3_-_197226351 0.43 ENST00000656428.1
discs large MAGUK scaffold protein 1
chr7_-_111392915 0.43 ENST00000450877.5
inner mitochondrial membrane peptidase subunit 2
chr10_-_28334439 0.42 ENST00000441595.2
membrane palmitoylated protein 7
chr1_+_192158448 0.42 ENST00000367460.4
regulator of G protein signaling 18
chr7_+_144000320 0.42 ENST00000641698.1
olfactory receptor family 6 subfamily B member 1
chr4_-_89029881 0.41 ENST00000506913.1
family with sequence similarity 13 member A
chr10_+_4786624 0.41 ENST00000533295.5
aldo-keto reductase family 1 member E2
chr7_+_90469634 0.40 ENST00000509356.2
PTTG1IP family member 2
chr10_+_94683722 0.39 ENST00000285979.11
cytochrome P450 family 2 subfamily C member 18
chr9_-_101383558 0.39 ENST00000674556.1
bile acid-CoA:amino acid N-acyltransferase
chr12_-_7503841 0.39 ENST00000359156.8
CD163 molecule
chr8_+_61287950 0.37 ENST00000519846.5
ENST00000325897.5
ENST00000523868.2
ENST00000518592.5
clavesin 1
chr6_-_130970428 0.37 ENST00000529208.5
erythrocyte membrane protein band 4.1 like 2
chr12_-_91178520 0.35 ENST00000425043.5
ENST00000420120.6
ENST00000441303.6
ENST00000456569.2
decorin
chr4_-_76023489 0.35 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr12_-_91153149 0.35 ENST00000550758.1
decorin
chrX_+_15790446 0.35 ENST00000380308.7
ENST00000307771.8
zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
chr12_-_47771029 0.35 ENST00000549151.5
ENST00000548919.5
Rap guanine nucleotide exchange factor 3
chr2_+_24049705 0.35 ENST00000380986.9
ENST00000452109.1
FKBP prolyl isomerase 1B
chr7_+_133253064 0.34 ENST00000393161.6
ENST00000253861.5
exocyst complex component 4
chr2_+_209580024 0.34 ENST00000392194.5
microtubule associated protein 2
chr2_+_24049673 0.33 ENST00000380991.8
FKBP prolyl isomerase 1B
chr12_-_7503744 0.33 ENST00000396620.7
ENST00000432237.3
CD163 molecule
chr6_+_20534441 0.33 ENST00000274695.8
ENST00000613575.4
CDK5 regulatory subunit associated protein 1 like 1
chr2_-_213151590 0.33 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr6_-_130222813 0.32 ENST00000437477.6
ENST00000439090.7
sterile alpha motif domain containing 3
chr4_+_40196907 0.32 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr9_-_92424427 0.31 ENST00000375550.5
osteomodulin
chr3_-_116444983 0.31 ENST00000333617.8
limbic system associated membrane protein
chr3_-_128487916 0.31 ENST00000430265.6
GATA binding protein 2
chr5_+_31193678 0.31 ENST00000265071.3
cadherin 6
chr3_-_127736329 0.30 ENST00000398101.7
monoglyceride lipase
chr13_+_31739520 0.30 ENST00000298386.7
relaxin family peptide receptor 2
chr9_-_4666495 0.30 ENST00000475086.5
spermatogenesis associated 6 like
chr1_-_75932392 0.30 ENST00000284142.7
ankyrin repeat and SOCS box containing 17
chr6_+_121435595 0.30 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr12_-_91180365 0.29 ENST00000547937.5
decorin
chr7_-_23347704 0.29 ENST00000619562.4
insulin like growth factor 2 mRNA binding protein 3
chr15_+_41256907 0.29 ENST00000560965.1
calcineurin like EF-hand protein 1
chr17_-_40782544 0.28 ENST00000301656.4
keratin 27
chr1_+_74235377 0.28 ENST00000326637.8
TNNI3 interacting kinase
chr2_-_208146150 0.28 ENST00000260988.5
crystallin gamma B
chr12_+_18738102 0.28 ENST00000317658.5
capping actin protein of muscle Z-line subunit alpha 3
chr10_+_94683771 0.27 ENST00000339022.6
cytochrome P450 family 2 subfamily C member 18
chr7_+_95485898 0.27 ENST00000428113.5
ankyrin repeat and SOCS box containing 4
chr13_+_31739542 0.27 ENST00000380314.2
relaxin family peptide receptor 2
chr11_+_6863057 0.27 ENST00000641461.1
olfactory receptor family 10 subfamily A member 2
chr12_-_76423256 0.27 ENST00000546946.5
oxysterol binding protein like 8
chr3_+_186717348 0.27 ENST00000447445.1
ENST00000287611.8
ENST00000644859.2
kininogen 1
chr15_+_40807055 0.27 ENST00000570108.5
ENST00000564258.5
ENST00000355341.8
ENST00000336455.9
zinc finger FYVE-type containing 19
chr12_-_91182784 0.27 ENST00000547568.6
ENST00000052754.10
ENST00000552962.5
decorin
chr8_-_100706931 0.26 ENST00000520868.5
poly(A) binding protein cytoplasmic 1
chr6_+_42050876 0.26 ENST00000465926.5
ENST00000482432.1
TATA-box binding protein associated factor 8
chr11_-_26572102 0.26 ENST00000455601.6
mucin 15, cell surface associated
chr9_+_34329545 0.26 ENST00000379158.7
nudix hydrolase 2
chr4_+_99574812 0.26 ENST00000422897.6
ENST00000265517.10
microsomal triglyceride transfer protein
chr2_+_87338511 0.25 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr14_+_66824439 0.25 ENST00000555456.1
gephyrin
chr11_-_13496018 0.25 ENST00000529816.1
parathyroid hormone
chr8_-_130386864 0.25 ENST00000521426.5
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr1_+_61952283 0.25 ENST00000307297.8
PATJ crumbs cell polarity complex component
chrX_+_12906612 0.25 ENST00000218032.7
toll like receptor 8
chr4_+_40197023 0.25 ENST00000381799.10
ras homolog family member H
chr2_+_90234809 0.25 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr13_-_36297838 0.25 ENST00000511166.1
CCDC169-SOHLH2 readthrough
chr17_+_47522931 0.24 ENST00000525007.5
ENST00000530173.6
aminopeptidase puromycin sensitive
chr14_-_74875998 0.24 ENST00000556489.4
ENST00000673765.1
prospero homeobox 2
chr9_+_34329495 0.24 ENST00000346365.8
ENST00000379155.9
ENST00000618590.1
nudix hydrolase 2
chr2_+_90172802 0.24 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr11_+_118077067 0.24 ENST00000522307.5
ENST00000523251.5
ENST00000437212.8
ENST00000522824.5
ENST00000522151.5
transmembrane serine protease 4
chr15_+_71096941 0.24 ENST00000355327.7
thrombospondin type 1 domain containing 4
chr17_+_75721327 0.24 ENST00000579662.5
integrin subunit beta 4
chr5_+_181040260 0.23 ENST00000515271.1
ENST00000327705.14
butyrophilin like 9
chr2_-_189179754 0.23 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr11_+_118077009 0.23 ENST00000616579.4
ENST00000534111.5
transmembrane serine protease 4
chr13_+_75804169 0.23 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr7_-_6009072 0.23 ENST00000642456.1
ENST00000642292.1
ENST00000441476.6
PMS1 homolog 2, mismatch repair system component
chr2_-_88979016 0.22 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr17_-_40755328 0.22 ENST00000312150.5
keratin 25
chr12_+_53097656 0.22 ENST00000301464.4
insulin like growth factor binding protein 6
chr2_+_1414382 0.22 ENST00000423320.5
ENST00000346956.7
ENST00000382198.5
thyroid peroxidase
chr3_-_37174578 0.22 ENST00000336686.9
LRR binding FLII interacting protein 2
chr1_-_235650748 0.22 ENST00000450593.5
ENST00000366598.8
G protein subunit gamma 4
chr19_-_57974527 0.21 ENST00000314391.3
chromosome 19 open reading frame 18
chr3_-_139539577 0.21 ENST00000619087.4
retinol binding protein 1
chr11_+_57763820 0.21 ENST00000674106.1
catenin delta 1
chr19_-_4558417 0.21 ENST00000586965.1
semaphorin 6B
chr4_-_83114715 0.21 ENST00000426923.2
ENST00000311507.9
ENST00000509973.5
placenta associated 8
chr7_+_138076453 0.21 ENST00000242375.8
ENST00000411726.6
aldo-keto reductase family 1 member D1
chrX_+_12906639 0.20 ENST00000311912.5
toll like receptor 8
chr9_-_4666347 0.20 ENST00000381890.9
ENST00000682582.1
spermatogenesis associated 6 like
chr2_+_167248638 0.20 ENST00000295237.10
xin actin binding repeat containing 2
chr2_+_233681877 0.20 ENST00000373426.4
UDP glucuronosyltransferase family 1 member A7
chr7_+_106865474 0.20 ENST00000359195.3
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr14_+_51489112 0.20 ENST00000356218.8
FERM domain containing 6
chrX_-_149505274 0.20 ENST00000428056.6
ENST00000340855.11
ENST00000370441.8
iduronate 2-sulfatase
chr12_+_55362975 0.19 ENST00000641576.1
olfactory receptor family 6 subfamily C member 75
chr12_+_21372899 0.19 ENST00000240652.8
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr11_-_13495984 0.19 ENST00000282091.6
parathyroid hormone
chr7_-_122702912 0.19 ENST00000447240.1
ENST00000434824.2
ring finger protein 148
chr3_+_130560334 0.19 ENST00000358511.10
collagen type VI alpha 6 chain
chr1_+_84181630 0.19 ENST00000610457.1
protein kinase cAMP-activated catalytic subunit beta
chr2_-_202870761 0.18 ENST00000420558.5
ENST00000418208.5
islet cell autoantigen 1 like
chrX_-_41665766 0.18 ENST00000643043.2
ENST00000486402.1
ENST00000646087.2
calcium/calmodulin dependent serine protein kinase
chr4_-_122456725 0.18 ENST00000226730.5
interleukin 2
chr9_-_70414657 0.18 ENST00000377126.4
Kruppel like factor 9
chr2_+_137964279 0.18 ENST00000329366.8
histamine N-methyltransferase
chrX_+_37780049 0.18 ENST00000378588.5
cytochrome b-245 beta chain
chr3_+_109136707 0.18 ENST00000622536.6
chromosome 3 open reading frame 85
chr1_-_241999091 0.18 ENST00000357246.4
microtubule associated protein 1 light chain 3 gamma
chr11_-_18236795 0.18 ENST00000278222.7
serum amyloid A4, constitutive
chr5_+_31193739 0.18 ENST00000514738.5
cadherin 6
chr3_+_141262614 0.18 ENST00000504264.5
2-phosphoxylose phosphatase 1
chr5_-_147906530 0.18 ENST00000318315.5
ENST00000515291.1
chromosome 5 open reading frame 46
chr6_-_26250625 0.18 ENST00000618052.2
H3 clustered histone 7
chr15_-_55270280 0.18 ENST00000564609.5
RAB27A, member RAS oncogene family
chrX_-_155264471 0.17 ENST00000369454.4
RAB39B, member RAS oncogene family
chr2_+_114442616 0.17 ENST00000410059.6
dipeptidyl peptidase like 10
chr17_-_82698637 0.17 ENST00000538809.6
ENST00000269347.10
ENST00000571995.6
RAB40B, member RAS oncogene family
chr7_-_6009019 0.17 ENST00000382321.5
ENST00000265849.12
PMS1 homolog 2, mismatch repair system component
chr11_-_104898670 0.17 ENST00000422698.6
caspase 12 (gene/pseudogene)
chr6_+_116461364 0.17 ENST00000368606.7
ENST00000368605.3
calcium homeostasis modulator family member 6
chr17_-_68955332 0.17 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr6_-_2750912 0.17 ENST00000274643.9
myosin light chain kinase family member 4
chr1_+_161721563 0.17 ENST00000367948.6
Fc receptor like B
chr10_-_103153609 0.17 ENST00000675985.1
5'-nucleotidase, cytosolic II
chr7_+_152074292 0.16 ENST00000434507.5
polypeptide N-acetylgalactosaminyltransferase 11
chr19_+_15793951 0.16 ENST00000308940.8
olfactory receptor family 10 subfamily H member 5
chr5_-_64768619 0.16 ENST00000513458.9
SREK1 interacting protein 1
chr12_-_10172117 0.16 ENST00000545927.5
ENST00000309539.8
ENST00000432556.6
ENST00000544577.5
oxidized low density lipoprotein receptor 1
chr17_-_3063607 0.16 ENST00000575751.1
olfactory receptor family 1 subfamily D member 5
chr17_-_4967790 0.16 ENST00000575142.5
ENST00000206020.8
sperm associated antigen 7
chr2_-_164842140 0.16 ENST00000496396.1
ENST00000629362.2
ENST00000445474.2
ENST00000483743.6
cordon-bleu WH2 repeat protein like 1
chr4_+_154563003 0.16 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chrX_-_50200988 0.16 ENST00000358526.7
A-kinase anchoring protein 4
chr6_+_160702238 0.16 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
plasminogen
chr11_-_64879709 0.16 ENST00000621096.4
EH domain containing 1
chr3_+_44625027 0.15 ENST00000344387.9
ENST00000383745.6
zinc finger protein 197
chr7_-_93226449 0.15 ENST00000394468.7
ENST00000453812.2
HEPACAM family member 2
chr14_+_23630109 0.15 ENST00000432832.6
dehydrogenase/reductase 2
chr1_+_198638968 0.15 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
protein tyrosine phosphatase receptor type C
chr16_-_84617547 0.15 ENST00000567786.2
coactosin like F-actin binding protein 1
chr7_+_95485934 0.15 ENST00000325885.6
ankyrin repeat and SOCS box containing 4
chr7_-_28180735 0.15 ENST00000283928.10
JAZF zinc finger 1
chr6_+_150866333 0.15 ENST00000618312.4
ENST00000423867.2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr6_+_7726089 0.14 ENST00000283147.7
bone morphogenetic protein 6
chr6_-_110815408 0.14 ENST00000368911.8
cyclin dependent kinase 19
chr12_-_18738006 0.14 ENST00000266505.12
ENST00000543242.5
ENST00000539072.5
ENST00000541966.5
ENST00000648272.1
phospholipase C zeta 1
chr1_+_248095184 0.14 ENST00000358120.3
ENST00000641893.1
olfactory receptor family 2 subfamily L member 13
chr18_+_44680093 0.14 ENST00000426838.8
ENST00000677068.1
SET binding protein 1
chr20_-_17558811 0.14 ENST00000536626.7
ENST00000377868.6
beaded filament structural protein 1
chr11_-_64879675 0.14 ENST00000359393.6
ENST00000433803.1
ENST00000411683.1
EH domain containing 1
chr7_-_155510158 0.14 ENST00000682997.1
canopy FGF signaling regulator 1
chr1_+_153416517 0.14 ENST00000368729.9
S100 calcium binding protein A7A
chr19_+_15728024 0.14 ENST00000305899.5
olfactory receptor family 10 subfamily H member 2
chr5_+_157180816 0.14 ENST00000422843.8
IL2 inducible T cell kinase
chr12_-_9869345 0.14 ENST00000228438.3
C-type lectin domain family 2 member B
chr7_-_107803215 0.13 ENST00000340010.10
ENST00000453332.1
solute carrier family 26 member 3
chr18_+_616711 0.13 ENST00000579494.1
clusterin like 1
chr2_-_210476687 0.13 ENST00000233714.8
ENST00000443314.5
ENST00000441020.7
ENST00000450366.7
ENST00000431941.6
LanC like 1
chr7_+_134866831 0.13 ENST00000435928.1
caldesmon 1
chr12_-_118359639 0.13 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAO kinase 3
chr3_-_108529322 0.13 ENST00000273353.4
myosin heavy chain 15
chr12_-_9999176 0.13 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr6_+_138773747 0.13 ENST00000617445.5
coiled-coil domain containing 28A
chr10_-_93482194 0.13 ENST00000358334.9
ENST00000371488.3
myoferlin
chr8_+_35235467 0.13 ENST00000404895.7
unc-5 netrin receptor D
chr5_-_78294656 0.13 ENST00000519295.5
ENST00000255194.11
adaptor related protein complex 3 subunit beta 1
chrX_-_139642889 0.13 ENST00000370576.9
MCF.2 cell line derived transforming sequence
chr12_-_50222694 0.12 ENST00000552783.5
LIM domain and actin binding 1
chr3_+_98130721 0.12 ENST00000641874.1
olfactory receptor family 5 subfamily H member 1
chr14_+_22304051 0.12 ENST00000390466.1
T cell receptor alpha variable 39
chr3_-_20186127 0.12 ENST00000425061.5
ENST00000443724.5
ENST00000421451.5
ENST00000452020.5
ENST00000417364.1
ENST00000306698.6
ENST00000419233.6
ENST00000263753.8
ENST00000437051.5
ENST00000442720.5
ENST00000412997.6
shugoshin 1
chr2_-_99254281 0.12 ENST00000409238.5
ENST00000423800.5
lysozyme g2
chr10_-_75109085 0.12 ENST00000607131.5
dual specificity phosphatase 13
chr8_-_100722731 0.12 ENST00000521865.6
ENST00000520804.2
ENST00000522720.2
ENST00000521067.1
poly(A) binding protein cytoplasmic 1
chr13_-_40982880 0.12 ENST00000635415.1
E74 like ETS transcription factor 1
chr7_-_87713287 0.12 ENST00000416177.1
ENST00000265724.8
ENST00000543898.5
ATP binding cassette subfamily B member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 0.5 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.7 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.4 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.5 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.3 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.9 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.3 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.5 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 1.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.3 GO:0036269 swimming behavior(GO:0036269)
0.1 0.7 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.8 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.5 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.3 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.5 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.3 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822)
0.0 0.2 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:1903762 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.5 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0032252 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.4 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.1 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.2 GO:0009804 coumarin metabolic process(GO:0009804) flavone metabolic process(GO:0051552)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.1 GO:0022018 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.0 1.1 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.3 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.3 GO:0006776 retinoic acid biosynthetic process(GO:0002138) vitamin A metabolic process(GO:0006776)
0.0 0.6 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.4 GO:0006544 glycine metabolic process(GO:0006544)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.0 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.5 GO:0031523 Myb complex(GO:0031523)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.4 GO:0089701 U2AF(GO:0089701)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.4 GO:0032389 MutLalpha complex(GO:0032389)
0.0 2.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0097169 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.4 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 0.7 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.4 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.1 1.1 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.3 GO:0008940 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.2 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.1 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.4 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.3 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.6 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.6 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.5 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.0 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.8 GO:0070063 RNA polymerase binding(GO:0070063)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones