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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXD11_HOXA11

Z-value: 0.83

Motif logo

Transcription factors associated with HOXD11_HOXA11

Gene Symbol Gene ID Gene Info
ENSG00000128713.14 HOXD11
ENSG00000005073.6 HOXA11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD11hg38_v1_chr2_+_176107272_1761072970.551.7e-03Click!
HOXA11hg38_v1_chr7_-_27185223_27185249-0.009.9e-01Click!

Activity profile of HOXD11_HOXA11 motif

Sorted Z-values of HOXD11_HOXA11 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD11_HOXA11

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_189179754 4.91 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr7_-_41703062 3.54 ENST00000242208.5
inhibin subunit beta A
chr2_-_215436061 3.47 ENST00000421182.5
ENST00000432072.6
ENST00000323926.10
ENST00000336916.8
ENST00000357867.8
ENST00000359671.5
ENST00000446046.5
ENST00000354785.11
ENST00000356005.8
ENST00000443816.5
ENST00000426059.1
fibronectin 1
chr11_+_111245725 3.33 ENST00000280325.7
chromosome 11 open reading frame 53
chr2_+_157257687 2.95 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr12_-_24902243 2.93 ENST00000538118.5
branched chain amino acid transaminase 1
chr5_-_39270623 2.84 ENST00000512138.1
ENST00000646045.2
FYN binding protein 1
chr1_+_84164962 2.43 ENST00000614872.4
ENST00000394839.6
protein kinase cAMP-activated catalytic subunit beta
chr5_+_149141817 2.40 ENST00000504238.5
actin binding LIM protein family member 3
chr21_-_30497160 2.33 ENST00000334058.3
keratin associated protein 19-4
chr4_-_67883987 2.25 ENST00000283916.11
transmembrane serine protease 11D
chr7_+_134779663 2.23 ENST00000361901.6
caldesmon 1
chr7_+_134779625 2.19 ENST00000454108.5
ENST00000361675.7
caldesmon 1
chr6_+_12290353 2.13 ENST00000379375.6
endothelin 1
chr2_-_216013582 2.10 ENST00000620139.4
melanoregulin
chr18_-_12656716 2.02 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
spire type actin nucleation factor 1
chr12_-_95116967 1.97 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr1_-_152414256 1.88 ENST00000271835.3
cornulin
chr2_-_31217511 1.88 ENST00000403897.4
calpain 14
chr9_+_122371036 1.86 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chr1_+_86547070 1.73 ENST00000370563.3
chloride channel accessory 4
chr12_-_91111460 1.69 ENST00000266718.5
lumican
chr1_+_31576485 1.67 ENST00000457433.6
ENST00000271064.12
tubulointerstitial nephritis antigen like 1
chr15_-_83283449 1.63 ENST00000569704.2
basonuclin 1
chr20_+_3786772 1.58 ENST00000344256.10
ENST00000379598.9
cell division cycle 25B
chr19_+_926001 1.50 ENST00000263620.8
AT-rich interaction domain 3A
chr20_+_38926312 1.49 ENST00000619304.4
ENST00000619850.2
family with sequence similarity 83 member D
chr1_+_192158448 1.40 ENST00000367460.4
regulator of G protein signaling 18
chr2_-_70553440 1.32 ENST00000450929.5
transforming growth factor alpha
chr4_+_168092530 1.28 ENST00000359299.8
annexin A10
chr9_+_122371014 1.28 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chr1_-_120054225 1.28 ENST00000602566.6
notch receptor 2
chr9_+_122370523 1.27 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chr2_+_28395511 1.26 ENST00000436647.1
FOS like 2, AP-1 transcription factor subunit
chr19_-_4558417 1.25 ENST00000586965.1
semaphorin 6B
chr9_+_102995308 1.25 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
cylicin 2
chr18_-_5396265 1.24 ENST00000579951.2
erythrocyte membrane protein band 4.1 like 3
chr12_-_52385649 1.24 ENST00000257951.3
keratin 84
chr15_-_79971164 1.23 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2 related protein A1
chr5_-_39219555 1.18 ENST00000512982.4
ENST00000351578.12
ENST00000509072.5
ENST00000504542.1
ENST00000506557.5
FYN binding protein 1
chr12_+_130162456 1.17 ENST00000539839.1
ENST00000229030.5
frizzled class receptor 10
chrX_+_136169833 1.17 ENST00000628032.2
four and a half LIM domains 1
chr8_-_90082871 1.17 ENST00000265431.7
calbindin 1
chr14_-_34713759 1.15 ENST00000673315.1
cofilin 2
chrX_+_136169624 1.12 ENST00000394153.6
four and a half LIM domains 1
chr15_+_67125707 1.09 ENST00000540846.6
SMAD family member 3
chr17_+_59155726 1.08 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
proline rich 11
chr2_+_31234144 1.06 ENST00000322054.10
EH domain containing 3
chr20_+_31514410 1.06 ENST00000335574.10
ENST00000340852.9
ENST00000398174.9
ENST00000466766.2
ENST00000498035.5
ENST00000344042.5
histocompatibility minor 13
chr14_-_56805648 1.05 ENST00000554788.5
ENST00000554845.1
ENST00000408990.8
orthodenticle homeobox 2
chr3_+_111911604 1.05 ENST00000495180.1
pleckstrin homology like domain family B member 2
chr12_+_92702843 1.03 ENST00000397833.3
pleckstrin homology and RhoGEF domain containing G7
chrX_+_136169664 1.02 ENST00000456445.5
four and a half LIM domains 1
chr12_-_30735014 0.99 ENST00000433722.6
caprin family member 2
chr10_-_88952763 0.97 ENST00000224784.10
actin alpha 2, smooth muscle
chr22_+_50170720 0.97 ENST00000159647.9
ENST00000395842.3
pannexin 2
chr3_-_37174578 0.96 ENST00000336686.9
LRR binding FLII interacting protein 2
chr1_+_116111395 0.96 ENST00000684484.1
ENST00000369500.4
mab-21 like 3
chr6_-_131000722 0.96 ENST00000528282.5
erythrocyte membrane protein band 4.1 like 2
chrX_+_136169891 0.94 ENST00000449474.5
four and a half LIM domains 1
chr7_+_134891566 0.90 ENST00000424922.5
ENST00000495522.1
caldesmon 1
chr11_+_35180279 0.88 ENST00000531873.5
CD44 molecule (Indian blood group)
chr4_+_143433491 0.88 ENST00000512843.1
GRB2 associated binding protein 1
chr11_+_63838902 0.87 ENST00000377810.8
microtubule affinity regulating kinase 2
chr1_-_237004440 0.87 ENST00000464121.3
metallothionein 1H like 1
chr7_+_80646436 0.87 ENST00000419819.2
CD36 molecule
chr3_+_101827982 0.86 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKB inhibitor zeta
chr1_-_28058087 0.85 ENST00000373864.5
EYA transcriptional coactivator and phosphatase 3
chr17_-_41397600 0.85 ENST00000251645.3
keratin 31
chr12_-_84892120 0.84 ENST00000680379.1
solute carrier family 6 member 15
chr13_+_108596152 0.82 ENST00000356711.7
ENST00000251041.10
myosin XVI
chr12_+_1691011 0.82 ENST00000357103.5
adiponectin receptor 2
chr11_-_107858777 0.82 ENST00000525815.6
solute carrier family 35 member F2
chr4_-_103077282 0.81 ENST00000503230.5
ENST00000503818.1
solute carrier family 9 member B2
chr8_+_12108172 0.79 ENST00000400078.3
zinc finger protein 705D
chr2_-_216013517 0.79 ENST00000263268.11
melanoregulin
chr1_-_93681829 0.78 ENST00000260502.11
BCAR3 adaptor protein, NSP family member
chr4_-_47981535 0.78 ENST00000402813.9
cyclic nucleotide gated channel subunit alpha 1
chr9_-_92878018 0.75 ENST00000332591.6
ENST00000375495.8
ENST00000395505.6
ENST00000395506.7
zinc finger protein 484
chr14_-_50561119 0.75 ENST00000555216.5
mitogen-activated protein kinase kinase kinase kinase 5
chr2_+_29113989 0.74 ENST00000404424.5
CAP-Gly domain containing linker protein family member 4
chr12_-_68225806 0.74 ENST00000229134.5
interleukin 26
chr19_-_10309783 0.74 ENST00000403352.1
ENST00000403903.7
zinc finger GATA like protein 1
chr2_+_100974849 0.74 ENST00000450763.1
neuronal PAS domain protein 2
chr1_+_157993601 0.74 ENST00000359209.11
kirre like nephrin family adhesion molecule 1
chr7_+_80369547 0.73 ENST00000435819.5
CD36 molecule
chr17_-_40984297 0.73 ENST00000377755.9
keratin 40
chr4_-_39977836 0.73 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr3_-_27456743 0.73 ENST00000295736.9
ENST00000428386.5
ENST00000428179.1
solute carrier family 4 member 7
chr1_-_110391041 0.72 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
solute carrier family 16 member 4
chr3_+_141262614 0.72 ENST00000504264.5
2-phosphoxylose phosphatase 1
chr1_+_157993273 0.72 ENST00000360089.8
ENST00000368173.7
kirre like nephrin family adhesion molecule 1
chr2_+_37344594 0.72 ENST00000404976.5
ENST00000338415.8
glutaminyl-peptide cyclotransferase
chr13_+_31945826 0.71 ENST00000647500.1
FRY microtubule binding protein
chr4_-_39032343 0.71 ENST00000381938.4
transmembrane protein 156
chr11_+_35180342 0.71 ENST00000639002.1
CD44 molecule (Indian blood group)
chr8_-_27837765 0.70 ENST00000521226.2
ENST00000301905.9
PDZ binding kinase
chr14_-_34713788 0.70 ENST00000341223.8
cofilin 2
chr2_+_24049673 0.69 ENST00000380991.8
FKBP prolyl isomerase 1B
chr1_-_6360677 0.69 ENST00000377845.7
acyl-CoA thioesterase 7
chr10_+_92593112 0.69 ENST00000260731.5
kinesin family member 11
chr16_-_56425424 0.68 ENST00000290649.10
autocrine motility factor receptor
chr12_+_92702983 0.67 ENST00000344636.6
ENST00000544406.2
pleckstrin homology and RhoGEF domain containing G7
chr1_-_158554405 0.67 ENST00000641282.1
ENST00000641622.1
olfactory receptor family 6 subfamily Y member 1
chr3_-_197226351 0.66 ENST00000656428.1
discs large MAGUK scaffold protein 1
chr21_+_38272410 0.66 ENST00000398934.5
ENST00000398930.5
potassium inwardly rectifying channel subfamily J member 15
chr22_+_18527802 0.66 ENST00000612978.5
transmembrane protein 191B
chr1_+_70411241 0.65 ENST00000370938.8
ENST00000346806.2
cystathionine gamma-lyase
chr2_+_24049705 0.65 ENST00000380986.9
ENST00000452109.1
FKBP prolyl isomerase 1B
chr18_+_23992773 0.64 ENST00000304621.10
tetratricopeptide repeat domain 39C
chr8_+_11809135 0.64 ENST00000528643.5
ENST00000525777.5
farnesyl-diphosphate farnesyltransferase 1
chr13_+_52455972 0.63 ENST00000490903.5
ENST00000480747.1
cytoskeleton associated protein 2
chr7_-_80922354 0.63 ENST00000419255.6
semaphorin 3C
chr6_-_27146841 0.63 ENST00000356950.2
H2B clustered histone 12
chr2_+_33134620 0.62 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr11_-_31806886 0.62 ENST00000640963.1
paired box 6
chr15_+_41256907 0.62 ENST00000560965.1
calcineurin like EF-hand protein 1
chr17_-_41489907 0.62 ENST00000328119.11
keratin 36
chr2_-_70553638 0.61 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
transforming growth factor alpha
chr4_-_99144238 0.61 ENST00000512499.5
ENST00000504125.1
ENST00000505590.5
ENST00000629236.2
ENST00000508393.5
ENST00000265512.12
alcohol dehydrogenase 4 (class II), pi polypeptide
chr14_+_56117702 0.61 ENST00000559044.5
pellino E3 ubiquitin protein ligase family member 2
chr16_+_11345429 0.61 ENST00000576027.1
ENST00000312499.6
ENST00000648619.1
RecQ mediated genome instability 2
chr15_-_99249523 0.60 ENST00000560235.1
ENST00000394132.7
ENST00000560860.5
ENST00000558078.5
ENST00000560772.5
tetratricopeptide repeat domain 23
chr1_-_155910881 0.60 ENST00000609492.1
ENST00000368322.7
Ras like without CAAX 1
chr1_-_155255441 0.60 ENST00000361361.7
ENST00000621094.4
family with sequence similarity 189 member B
chr7_+_80646305 0.60 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr17_+_56153458 0.60 ENST00000318698.6
ENST00000682825.1
ENST00000566473.6
ankyrin repeat and fibronectin type III domain containing 1
chr3_-_185821092 0.60 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chr2_+_33134579 0.59 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr22_+_35717872 0.59 ENST00000249044.2
apolipoprotein L5
chr2_+_218607861 0.58 ENST00000450993.7
phospholipase C delta 4
chr22_+_22906342 0.58 ENST00000390325.2
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr14_+_73239599 0.58 ENST00000554301.5
ENST00000555445.5
papilin, proteoglycan like sulfated glycoprotein
chr11_+_73272201 0.57 ENST00000393590.3
pyrimidinergic receptor P2Y6
chr7_-_111392915 0.56 ENST00000450877.5
inner mitochondrial membrane peptidase subunit 2
chr8_-_130386864 0.56 ENST00000521426.5
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr17_-_41369807 0.56 ENST00000251646.8
keratin 33B
chr17_+_17179527 0.55 ENST00000579361.1
myosin phosphatase Rho interacting protein
chr1_+_81306096 0.55 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
adhesion G protein-coupled receptor L2
chr9_-_21305313 0.55 ENST00000610521.2
interferon alpha 5
chr2_+_200585987 0.55 ENST00000374700.7
aldehyde oxidase 1
chr10_-_96271508 0.55 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr4_-_108762964 0.54 ENST00000512646.5
ENST00000411864.6
ENST00000296486.8
ENST00000510706.5
ethanolamine-phosphate phospho-lyase
chr21_+_38272291 0.54 ENST00000438657.5
potassium inwardly rectifying channel subfamily J member 15
chr8_+_124474843 0.54 ENST00000303545.4
ring finger protein 139
chr6_-_27807916 0.53 ENST00000377401.3
H2B clustered histone 13
chr11_-_31811034 0.53 ENST00000638250.1
paired box 6
chr4_+_85604146 0.52 ENST00000512201.5
Rho GTPase activating protein 24
chr6_-_29368865 0.52 ENST00000641768.1
olfactory receptor family 5 subfamily V member 1
chr19_-_53132873 0.52 ENST00000601493.5
ENST00000599261.5
ENST00000597503.5
ENST00000500065.8
ENST00000594011.5
ENST00000595193.5
ENST00000595813.5
ENST00000600574.5
ENST00000596051.1
ENST00000601110.5
ENST00000243643.9
ENST00000421033.5
zinc finger protein 415
chr12_-_18090185 0.52 ENST00000229002.6
ENST00000538724.6
RERG like
chr17_-_76570544 0.51 ENST00000640006.1
novel protein
chr3_-_98523013 0.51 ENST00000394181.6
ENST00000508902.5
ENST00000394180.6
claudin domain containing 1
chr9_+_128322540 0.51 ENST00000609948.1
ENST00000608951.5
coenzyme Q4
chr6_+_63521738 0.51 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr1_+_209686173 0.51 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr9_-_101442403 0.51 ENST00000648758.1
aldolase, fructose-bisphosphate B
chr1_+_154429315 0.51 ENST00000476006.5
interleukin 6 receptor
chr7_+_1688119 0.51 ENST00000424383.4
extracellular leucine rich repeat and fibronectin type III domain containing 1
chr1_-_89175997 0.50 ENST00000294671.3
ENST00000650452.1
guanylate binding protein 7
chr6_-_104859828 0.50 ENST00000519645.5
ENST00000262903.9
ENST00000369125.6
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr17_+_59940908 0.49 ENST00000591035.1
novel protein
chr4_+_70383123 0.49 ENST00000304915.8
submaxillary gland androgen regulated protein 3B
chr15_-_55249029 0.49 ENST00000566877.5
RAB27A, member RAS oncogene family
chr10_-_114144599 0.49 ENST00000428953.1
coiled-coil domain containing 186
chr11_+_73272332 0.49 ENST00000540124.6
ENST00000536225.2
pyrimidinergic receptor P2Y6
chr10_+_100462969 0.48 ENST00000343737.6
Wnt family member 8B
chr9_-_92482350 0.48 ENST00000375543.2
asporin
chr3_-_151316795 0.48 ENST00000260843.5
G protein-coupled receptor 87
chr4_+_186227501 0.48 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
kallikrein B1
chr9_+_121651594 0.48 ENST00000408936.7
DAB2 interacting protein
chr11_-_13496018 0.48 ENST00000529816.1
parathyroid hormone
chr1_-_43453792 0.47 ENST00000372434.5
ENST00000486909.1
hydroxypyruvate isomerase (putative)
chr6_+_26199509 0.47 ENST00000356530.5
H2B clustered histone 7
chr13_+_45464901 0.47 ENST00000349995.10
component of oligomeric golgi complex 3
chr14_+_35122660 0.47 ENST00000603544.5
protein only RNase P catalytic subunit
chr9_-_131270493 0.47 ENST00000372269.7
ENST00000464831.1
family with sequence similarity 78 member A
chr15_+_67128103 0.47 ENST00000558894.5
SMAD family member 3
chr3_+_57890011 0.46 ENST00000494088.6
ENST00000438794.5
sarcolemma associated protein
chr4_-_76007501 0.46 ENST00000264888.6
C-X-C motif chemokine ligand 9
chr3_-_193554799 0.46 ENST00000295548.3
ATPase 13A4
chr10_-_13972355 0.46 ENST00000264546.10
FERM domain containing 4A
chr7_-_48029102 0.46 ENST00000297325.9
ENST00000412142.5
ENST00000395572.6
Sad1 and UNC84 domain containing 3
chr3_-_142029108 0.46 ENST00000497579.5
transcription factor Dp-2
chr19_-_19515542 0.45 ENST00000585580.4
testis specific serine kinase 6
chr4_-_103076688 0.45 ENST00000394785.9
solute carrier family 9 member B2
chrX_-_153321759 0.45 ENST00000436629.3
PNMA family member 6F
chr4_+_153152163 0.45 ENST00000676423.1
ENST00000675745.1
ENST00000676348.1
ENST00000676408.1
ENST00000674874.1
ENST00000675315.1
ENST00000675518.1
tripartite motif containing 2
novel protein
chr7_-_86965872 0.45 ENST00000398276.6
ENST00000416314.5
ENST00000425689.1
endosome-lysosome associated apoptosis and autophagy regulator family member 2
chr19_-_7040179 0.44 ENST00000381394.9
methyl-CpG binding domain protein 3 like 4
chr3_+_44338119 0.44 ENST00000383746.7
ENST00000417237.5
T cell activation inhibitor, mitochondrial
chr2_+_89947508 0.44 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr4_-_22443110 0.44 ENST00000508133.5
adhesion G protein-coupled receptor A3
chr21_+_38272250 0.44 ENST00000398932.5
potassium inwardly rectifying channel subfamily J member 15
chr10_-_101839818 0.44 ENST00000348850.9
potassium voltage-gated channel interacting protein 2
chr7_+_134843884 0.44 ENST00000445569.6
caldesmon 1
chr6_+_27815010 0.44 ENST00000621112.2
H2B clustered histone 14
chr8_-_28386417 0.43 ENST00000521185.5
ENST00000520290.5
ENST00000344423.10
zinc finger protein 395
chr15_+_90868580 0.43 ENST00000268171.8
furin, paired basic amino acid cleaving enzyme
chrX_-_37847562 0.43 ENST00000378578.9
dynein light chain Tctex-type 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.2 3.5 GO:0060279 positive regulation of ovulation(GO:0060279)
1.2 3.5 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.7 2.1 GO:0030185 nitric oxide transport(GO:0030185)
0.6 2.9 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.3 2.4 GO:0097338 response to clozapine(GO:0097338)
0.3 0.9 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.3 0.3 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.3 1.6 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 2.2 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 4.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 2.0 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.2 1.0 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.2 0.6 GO:0070409 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.2 0.8 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.2 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.5 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 0.7 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.2 0.7 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.2 0.7 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.2 0.7 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.2 2.9 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.7 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2 1.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 1.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 1.2 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.4 GO:1900390 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 1.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 1.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.8 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 1.3 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 0.4 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.7 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.5 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.4 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.4 GO:0006566 threonine metabolic process(GO:0006566)
0.1 1.6 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 1.7 GO:0007144 female meiosis I(GO:0007144)
0.1 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.3 GO:0022012 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.1 0.7 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.6 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 1.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.4 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 1.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.6 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.6 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.2 GO:0072141 renal interstitial fibroblast development(GO:0072141)
0.1 0.3 GO:0015847 putrescine transport(GO:0015847)
0.1 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.4 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.5 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.6 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.3 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 1.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.3 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.1 0.3 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.6 GO:0051552 flavone metabolic process(GO:0051552)
0.1 1.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.5 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.2 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.1 0.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 1.2 GO:0035878 nail development(GO:0035878)
0.1 0.8 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.2 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1 2.9 GO:0032402 melanosome transport(GO:0032402)
0.1 1.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 1.6 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.3 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 1.0 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.5 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.2 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.4 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.1 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.4 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 0.3 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.4 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.3 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 1.3 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.1 0.4 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.4 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.4 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.1 0.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.2 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.3 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.1 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.3 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) farnesyl diphosphate metabolic process(GO:0045338)
0.1 0.1 GO:2000405 negative regulation of T cell migration(GO:2000405)
0.1 0.3 GO:0032445 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 1.1 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.2 GO:0032599 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.1 0.2 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 4.9 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 0.3 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.1 0.3 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.7 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.4 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 1.2 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 1.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.2 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.2 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.7 GO:0051775 response to redox state(GO:0051775)
0.0 0.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.3 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.9 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0035054 septum secundum development(GO:0003285) atrial septum secundum morphogenesis(GO:0003290) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.1 GO:1902161 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.3 GO:0051414 response to cortisol(GO:0051414)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.7 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.4 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.3 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 1.5 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 1.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 1.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 0.1 GO:0032752 response to molecule of fungal origin(GO:0002238) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.0 5.2 GO:0031424 keratinization(GO:0031424)
0.0 4.3 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.0 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0 0.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:0036245 cellular response to menadione(GO:0036245)
0.0 0.3 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.4 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.4 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.3 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.6 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.3 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.1 GO:1903978 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) regulation of microglial cell activation(GO:1903978)
0.0 0.5 GO:1901032 negative regulation of response to reactive oxygen species(GO:1901032) negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.1 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.3 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 1.0 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.0 GO:2000078 positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.1 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.3 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 2.0 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0035696 monocyte extravasation(GO:0035696)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.9 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 2.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.0 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 2.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.4 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.4 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.3 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.8 GO:0051646 mitochondrion localization(GO:0051646)
0.0 0.2 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.2 GO:0097107 postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.3 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 1.4 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.5 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.3 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.1 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0 0.5 GO:0033198 response to ATP(GO:0033198)
0.0 0.3 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.3 GO:0015865 purine nucleotide transport(GO:0015865)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.7 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.0 GO:0060399 regulation of growth hormone receptor signaling pathway(GO:0060398) positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.7 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.0 GO:1904970 brush border assembly(GO:1904970)
0.0 0.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0005588 collagen type V trimer(GO:0005588)
1.2 3.5 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.7 2.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 1.2 GO:0033150 cytoskeletal calyx(GO:0033150)
0.4 5.7 GO:0030478 actin cap(GO:0030478)
0.3 3.6 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 1.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.2 1.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 1.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 2.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.5 GO:1990032 parallel fiber(GO:1990032)
0.1 0.1 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.2 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.1 0.4 GO:0072557 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.1 0.9 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 1.0 GO:0008091 spectrin(GO:0008091)
0.1 1.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.0 GO:0045180 basal cortex(GO:0045180)
0.1 1.2 GO:0033270 paranode region of axon(GO:0033270)
0.1 1.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 1.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0032044 DSIF complex(GO:0032044)
0.0 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.7 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 4.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0002079 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.0 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 6.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.9 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 1.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 2.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.6 2.9 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4 1.3 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.4 3.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 2.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 0.6 GO:0035276 ethanol binding(GO:0035276)
0.3 2.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 0.8 GO:0055100 adiponectin binding(GO:0055100)
0.3 1.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.3 1.6 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.3 0.8 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 1.2 GO:0050436 microfibril binding(GO:0050436)
0.2 1.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 5.6 GO:0005523 tropomyosin binding(GO:0005523)
0.2 0.2 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.2 0.5 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 1.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.2 0.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.5 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.2 0.5 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.2 1.0 GO:0005499 vitamin D binding(GO:0005499)
0.2 0.8 GO:0004882 androgen receptor activity(GO:0004882)
0.2 0.5 GO:0008903 hydroxypyruvate isomerase activity(GO:0008903)
0.1 0.6 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 2.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.3 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 1.0 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.8 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 2.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.6 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.4 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.4 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.1 0.5 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.6 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.3 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.3 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.1 0.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.7 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.4 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 1.0 GO:0042731 PH domain binding(GO:0042731)
0.1 1.0 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.6 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 8.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.3 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 1.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.4 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 1.2 GO:0051400 BH domain binding(GO:0051400)
0.1 0.4 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.3 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 3.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 3.5 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.6 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.8 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.7 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.9 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.5 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.5 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0030942 signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0001626 nociceptin receptor activity(GO:0001626)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 3.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 2.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.0 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 4.5 GO:0017171 serine hydrolase activity(GO:0017171)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 4.0 PID ALK1 PATHWAY ALK1 signaling events
0.1 4.4 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 4.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.9 PID EPO PATHWAY EPO signaling pathway
0.0 0.9 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 2.0 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 4.3 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 6.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 2.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 3.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 4.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 2.0 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 1.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.9 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 3.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 2.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.8 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels