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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXD4

Z-value: 0.47

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Transcription factors associated with HOXD4

Gene Symbol Gene ID Gene Info
HOXD4
ENSG00000170166.6 HOXD4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD4hg38_v1_chr2_+_176151543_176151559-0.154.3e-01Click!

Activity profile of HOXD4 motif

Sorted Z-values of HOXD4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_-_7940444 0.61 ENST00000378789.4
HAO1
hydroxyacid oxidase 1
chr17_+_9576627 0.58 ENST00000396219.7
ENST00000352665.10
CFAP52
cilia and flagella associated protein 52
chr7_+_92057602 0.57 ENST00000491695.2
AKAP9
A-kinase anchoring protein 9
chr13_+_42781578 0.53 ENST00000313851.3
FAM216B
family with sequence similarity 216 member B
chr18_+_63702958 0.53 ENST00000544088.6
SERPINB11
serpin family B member 11
chr12_+_9827517 0.52 ENST00000537723.5
KLRF1
killer cell lectin like receptor F1
chr17_-_10549694 0.47 ENST00000622564.4
MYH2
myosin heavy chain 2
chr3_+_63652663 0.45 ENST00000343837.8
ENST00000469440.5
SNTN
sentan, cilia apical structure protein
chr12_-_39340963 0.44 ENST00000552961.5
KIF21A
kinesin family member 21A
chr2_-_158380960 0.43 ENST00000409187.5
CCDC148
coiled-coil domain containing 148
chr7_-_122699108 0.40 ENST00000340112.3
RNF133
ring finger protein 133
chr7_-_25228485 0.39 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr4_+_68447453 0.38 ENST00000305363.9
TMPRSS11E
transmembrane serine protease 11E
chr13_+_23570370 0.38 ENST00000403372.6
ENST00000248484.9
TNFRSF19
TNF receptor superfamily member 19
chr3_+_159069252 0.37 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr17_-_10549612 0.36 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
MYH2
myosin heavy chain 2
chr2_-_55296361 0.36 ENST00000647547.1
CCDC88A
coiled-coil domain containing 88A
chr8_-_71361860 0.34 ENST00000303824.11
ENST00000645451.1
EYA1
EYA transcriptional coactivator and phosphatase 1
chr6_-_75363003 0.33 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr8_-_101790934 0.32 ENST00000523645.5
ENST00000520346.1
ENST00000220931.11
ENST00000522448.5
ENST00000522951.5
ENST00000522252.5
ENST00000519098.5
NCALD
neurocalcin delta
chr16_-_2329687 0.29 ENST00000567910.1
ABCA3
ATP binding cassette subfamily A member 3
chr17_-_10549652 0.29 ENST00000245503.10
MYH2
myosin heavy chain 2
chr6_-_49744378 0.29 ENST00000371159.8
ENST00000263045.9
CRISP3
cysteine rich secretory protein 3
chr6_-_87095059 0.28 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
CGA
glycoprotein hormones, alpha polypeptide
chr6_-_49744434 0.28 ENST00000433368.6
ENST00000354620.4
CRISP3
cysteine rich secretory protein 3
chr4_-_68245683 0.27 ENST00000332644.6
TMPRSS11B
transmembrane serine protease 11B
chr10_-_96359273 0.25 ENST00000393871.5
ENST00000419479.5
ENST00000393870.3
OPALIN
oligodendrocytic myelin paranodal and inner loop protein
chr4_+_73481737 0.24 ENST00000226355.5
AFM
afamin
chr3_+_97764728 0.24 ENST00000463745.6
ARL6
ADP ribosylation factor like GTPase 6
chr2_+_190180835 0.24 ENST00000340623.4
C2orf88
chromosome 2 open reading frame 88
chr13_-_23433676 0.23 ENST00000682547.1
ENST00000455470.6
ENST00000382292.9
SACS
sacsin molecular chaperone
chr1_+_182450132 0.23 ENST00000294854.13
RGSL1
regulator of G protein signaling like 1
chr5_+_70025247 0.22 ENST00000380751.9
ENST00000380750.8
ENST00000503931.5
ENST00000506542.1
SERF1B
small EDRK-rich factor 1B
chr4_-_129093454 0.22 ENST00000281142.10
ENST00000511426.5
SCLT1
sodium channel and clathrin linker 1
chr4_-_152679984 0.22 ENST00000304385.8
ENST00000504064.1
TMEM154
transmembrane protein 154
chr12_-_56741535 0.22 ENST00000647707.1
ENSG00000285625.1
novel protein
chr5_+_69565122 0.21 ENST00000507595.1
GTF2H2C
GTF2H2 family member C
chr12_-_86256267 0.21 ENST00000620241.4
MGAT4C
MGAT4 family member C
chr4_-_129093377 0.21 ENST00000506368.5
ENST00000439369.6
ENST00000503215.5
SCLT1
sodium channel and clathrin linker 1
chr8_-_71362054 0.21 ENST00000340726.8
EYA1
EYA transcriptional coactivator and phosphatase 1
chr22_+_41092869 0.20 ENST00000674155.1
EP300
E1A binding protein p300
chr2_+_108377947 0.20 ENST00000272452.7
SULT1C4
sulfotransferase family 1C member 4
chr4_-_174263080 0.19 ENST00000615392.4
FBXO8
F-box protein 8
chr3_+_97821984 0.19 ENST00000389622.7
CRYBG3
crystallin beta-gamma domain containing 3
chr2_+_190180930 0.19 ENST00000443551.2
C2orf88
chromosome 2 open reading frame 88
chr10_-_17129786 0.19 ENST00000377833.10
CUBN
cubilin
chr5_-_111512473 0.18 ENST00000296632.8
ENST00000512160.5
ENST00000509887.5
STARD4
StAR related lipid transfer domain containing 4
chrX_+_77910656 0.18 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATP7A
PGK1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr10_+_94089067 0.17 ENST00000371375.1
ENST00000675218.1
PLCE1
phospholipase C epsilon 1
chr18_-_21703688 0.17 ENST00000584464.1
ENST00000578270.5
ABHD3
abhydrolase domain containing 3, phospholipase
chr5_+_31193739 0.16 ENST00000514738.5
CDH6
cadherin 6
chr13_-_61415508 0.16 ENST00000409204.4
PCDH20
protocadherin 20
chr4_-_69639642 0.15 ENST00000604629.6
ENST00000604021.1
UGT2A2
UDP glucuronosyltransferase family 2 member A2
chr19_-_44401575 0.15 ENST00000591679.5
ENST00000544719.6
ENST00000614994.5
ENST00000585868.1
ENST00000588212.1
ZNF285
ENSG00000267173.1
zinc finger protein 285
novel protein
chr13_+_108629605 0.14 ENST00000457511.7
MYO16
myosin XVI
chr1_-_150765785 0.14 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
CTSS
cathepsin S
chr6_-_44313306 0.14 ENST00000244571.5
AARS2
alanyl-tRNA synthetase 2, mitochondrial
chr11_-_40294089 0.14 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chrX_+_37990773 0.14 ENST00000341016.5
H2AP
H2A.P histone
chr13_-_23433735 0.14 ENST00000423156.2
ENST00000683210.1
ENST00000682775.1
ENST00000684497.1
ENST00000682944.1
ENST00000683489.1
ENST00000684385.1
ENST00000683680.1
SACS
sacsin molecular chaperone
chr1_-_150765735 0.14 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
CTSS
cathepsin S
chr5_-_22853320 0.13 ENST00000504376.6
ENST00000382254.6
CDH12
cadherin 12
chr8_+_75539893 0.13 ENST00000674002.1
HNF4G
hepatocyte nuclear factor 4 gamma
chr20_+_8789517 0.13 ENST00000437439.2
PLCB1
phospholipase C beta 1
chr5_+_31193678 0.13 ENST00000265071.3
CDH6
cadherin 6
chr18_+_24460655 0.13 ENST00000426880.2
HRH4
histamine receptor H4
chr1_-_100894818 0.12 ENST00000370114.8
EXTL2
exostosin like glycosyltransferase 2
chr4_+_127632926 0.12 ENST00000335251.11
INTU
inturned planar cell polarity protein
chr11_+_66011994 0.12 ENST00000312134.3
CST6
cystatin E/M
chr17_-_37542361 0.12 ENST00000614196.1
SYNRG
synergin gamma
chr4_-_142305935 0.12 ENST00000511838.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr1_-_100894775 0.12 ENST00000416479.1
ENST00000370113.7
EXTL2
exostosin like glycosyltransferase 2
chr3_+_142623386 0.11 ENST00000337777.7
ENST00000497199.5
PLS1
plastin 1
chr7_-_22193728 0.11 ENST00000620335.4
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr2_+_71453538 0.11 ENST00000258104.8
DYSF
dysferlin
chrX_+_56563569 0.11 ENST00000338222.7
UBQLN2
ubiquilin 2
chr4_+_158210479 0.11 ENST00000504569.5
ENST00000509278.5
ENST00000514558.5
ENST00000503200.5
ENST00000296529.11
TMEM144
transmembrane protein 144
chr10_+_84424919 0.11 ENST00000543283.2
ENST00000494586.5
CCSER2
coiled-coil serine rich protein 2
chr19_-_13953302 0.11 ENST00000585607.1
ENST00000538517.6
ENST00000587458.1
ENST00000538371.6
PODNL1
podocan like 1
chrX_-_23884017 0.11 ENST00000633372.1
APOO
apolipoprotein O
chr9_+_117704382 0.10 ENST00000646089.1
ENST00000355622.8
ENSG00000285082.2
TLR4
novel protein
toll like receptor 4
chr15_+_76336755 0.10 ENST00000290759.9
ISL2
ISL LIM homeobox 2
chr2_+_27663441 0.10 ENST00000326019.10
ENST00000613058.4
SLC4A1AP
solute carrier family 4 member 1 adaptor protein
chr9_+_273026 0.10 ENST00000682249.1
ENST00000453981.5
ENST00000487230.5
ENST00000469391.5
DOCK8
dedicator of cytokinesis 8
chr4_-_84966637 0.10 ENST00000295888.9
WDFY3
WD repeat and FYVE domain containing 3
chr12_+_112906777 0.10 ENST00000452357.7
ENST00000445409.7
OAS1
2'-5'-oligoadenylate synthetase 1
chr12_+_12785652 0.10 ENST00000356591.5
APOLD1
apolipoprotein L domain containing 1
chr6_-_53148822 0.10 ENST00000259803.8
GCM1
glial cells missing transcription factor 1
chr6_+_46793379 0.10 ENST00000230588.9
ENST00000611727.2
MEP1A
meprin A subunit alpha
chr10_-_72217126 0.10 ENST00000317126.8
ASCC1
activating signal cointegrator 1 complex subunit 1
chr9_-_21368057 0.10 ENST00000449498.2
IFNA13
interferon alpha 13
chr19_-_15815664 0.10 ENST00000641419.1
OR10H1
olfactory receptor family 10 subfamily H member 1
chr19_+_48325323 0.09 ENST00000596315.5
EMP3
epithelial membrane protein 3
chr4_+_168497066 0.09 ENST00000261509.10
PALLD
palladin, cytoskeletal associated protein
chr11_-_129192198 0.09 ENST00000310343.13
ARHGAP32
Rho GTPase activating protein 32
chr19_+_48325522 0.09 ENST00000594198.1
ENST00000270221.11
ENST00000597279.5
ENST00000593437.1
EMP3
epithelial membrane protein 3
chr6_-_26250625 0.09 ENST00000618052.2
H3C7
H3 clustered histone 7
chr5_-_35047935 0.09 ENST00000510428.1
ENST00000231420.11
AGXT2
alanine--glyoxylate aminotransferase 2
chr17_-_28406160 0.09 ENST00000618626.1
ENST00000612814.5
SLC46A1
solute carrier family 46 member 1
chr15_+_36594868 0.08 ENST00000566807.5
ENST00000643612.1
ENST00000567389.5
ENST00000562877.5
CDIN1
CDAN1 interacting nuclease 1
chr7_-_22193824 0.08 ENST00000401957.6
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr1_+_149782671 0.08 ENST00000444948.5
ENST00000369168.5
FCGR1A
Fc fragment of IgG receptor Ia
chr9_-_21368962 0.08 ENST00000610660.1
IFNA13
interferon alpha 13
chr3_+_4680617 0.08 ENST00000648212.1
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chr6_+_42746958 0.08 ENST00000614467.4
BICRAL
BRD4 interacting chromatin remodeling complex associated protein like
chr2_+_167187364 0.08 ENST00000672671.1
XIRP2
xin actin binding repeat containing 2
chr15_+_92900189 0.08 ENST00000626874.2
ENST00000627622.1
ENST00000629346.2
ENST00000628375.2
ENST00000420239.7
ENST00000394196.9
CHD2
chromodomain helicase DNA binding protein 2
chr10_+_52128343 0.08 ENST00000672084.1
PRKG1
protein kinase cGMP-dependent 1
chr2_-_165204042 0.07 ENST00000283254.12
ENST00000453007.1
SCN3A
sodium voltage-gated channel alpha subunit 3
chr18_+_24460630 0.07 ENST00000256906.5
HRH4
histamine receptor H4
chr8_+_42697339 0.07 ENST00000289957.3
ENST00000534391.1
CHRNB3
cholinergic receptor nicotinic beta 3 subunit
chr5_-_179617581 0.07 ENST00000523449.5
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1
chr7_+_77798832 0.07 ENST00000415251.6
ENST00000275575.11
PHTF2
putative homeodomain transcription factor 2
chr4_-_137532452 0.07 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
PCDH18
protocadherin 18
chr3_+_15003912 0.07 ENST00000406272.6
ENST00000617312.4
NR2C2
nuclear receptor subfamily 2 group C member 2
chr22_-_28712136 0.07 ENST00000464581.6
CHEK2
checkpoint kinase 2
chr11_-_129192291 0.06 ENST00000682385.1
ARHGAP32
Rho GTPase activating protein 32
chr5_+_69415065 0.06 ENST00000647531.1
ENST00000645446.1
ENST00000325631.10
ENST00000454295.6
MARVELD2
MARVEL domain containing 2
chr8_-_42843201 0.06 ENST00000529779.1
ENST00000345117.2
ENST00000254250.7
THAP1
THAP domain containing 1
chr6_+_28349907 0.06 ENST00000252211.7
ENST00000341464.9
ENST00000377255.3
ZKSCAN3
zinc finger with KRAB and SCAN domains 3
chr15_+_92900338 0.06 ENST00000625990.3
CHD2
chromodomain helicase DNA binding protein 2
chr7_+_77798750 0.06 ENST00000416283.6
ENST00000422959.6
ENST00000307305.12
ENST00000424760.5
PHTF2
putative homeodomain transcription factor 2
chr1_+_115029823 0.06 ENST00000256592.3
TSHB
thyroid stimulating hormone subunit beta
chr4_+_40197023 0.06 ENST00000381799.10
RHOH
ras homolog family member H
chr7_+_138460238 0.06 ENST00000343526.9
TRIM24
tripartite motif containing 24
chr2_+_223957431 0.06 ENST00000258383.4
MRPL44
mitochondrial ribosomal protein L44
chr1_+_28438104 0.06 ENST00000633167.1
ENST00000373836.4
PHACTR4
phosphatase and actin regulator 4
chr5_+_141966820 0.06 ENST00000513019.5
ENST00000394519.5
ENST00000356143.5
RNF14
ring finger protein 14
chr4_+_168497044 0.06 ENST00000505667.6
PALLD
palladin, cytoskeletal associated protein
chr1_-_113871665 0.06 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
PTPN22
protein tyrosine phosphatase non-receptor type 22
chr20_-_31390483 0.06 ENST00000376315.2
DEFB119
defensin beta 119
chr15_+_21651844 0.06 ENST00000623441.1
OR4N4C
olfactory receptor family 4 subfamily N member 4C
chr18_-_24311495 0.05 ENST00000357041.8
OSBPL1A
oxysterol binding protein like 1A
chr3_+_111998915 0.05 ENST00000478951.6
TAGLN3
transgelin 3
chr6_-_136526177 0.05 ENST00000617204.4
MAP7
microtubule associated protein 7
chr10_-_14330879 0.05 ENST00000357447.7
FRMD4A
FERM domain containing 4A
chr1_-_246193727 0.05 ENST00000391836.3
SMYD3
SET and MYND domain containing 3
chrX_-_13817027 0.05 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
GPM6B
glycoprotein M6B
chr22_-_28711931 0.05 ENST00000434810.5
ENST00000456369.5
CHEK2
checkpoint kinase 2
chr7_-_29146436 0.05 ENST00000396276.7
CPVL
carboxypeptidase vitellogenic like
chr3_-_18438767 0.05 ENST00000454909.6
SATB1
SATB homeobox 1
chr4_-_129093548 0.05 ENST00000503401.1
SCLT1
sodium channel and clathrin linker 1
chr2_-_162838728 0.05 ENST00000328032.8
ENST00000332142.10
KCNH7
potassium voltage-gated channel subfamily H member 7
chr8_-_19013649 0.05 ENST00000440756.4
PSD3
pleckstrin and Sec7 domain containing 3
chr1_-_92486916 0.05 ENST00000294702.6
GFI1
growth factor independent 1 transcriptional repressor
chr9_-_94640130 0.05 ENST00000414122.1
FBP1
fructose-bisphosphatase 1
chr1_+_210328244 0.04 ENST00000541565.5
ENST00000413764.6
HHAT
hedgehog acyltransferase
chr1_+_86914616 0.04 ENST00000370550.10
ENST00000370551.8
HS2ST1
heparan sulfate 2-O-sulfotransferase 1
chr7_-_137343752 0.04 ENST00000393083.2
PTN
pleiotrophin
chr7_-_29146527 0.04 ENST00000265394.10
CPVL
carboxypeptidase vitellogenic like
chr12_-_118190510 0.04 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr20_-_31390580 0.04 ENST00000339144.3
ENST00000376321.4
DEFB119
defensin beta 119
chr17_-_41047267 0.04 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr2_+_186590022 0.04 ENST00000261023.8
ENST00000374907.7
ITGAV
integrin subunit alpha V
chr4_-_39977836 0.04 ENST00000303538.13
ENST00000503396.5
PDS5A
PDS5 cohesin associated factor A
chr4_-_151227881 0.03 ENST00000652233.1
ENST00000514152.5
SH3D19
SH3 domain containing 19
chr2_-_174597728 0.03 ENST00000409891.5
ENST00000410117.5
WIPF1
WAS/WASL interacting protein family member 1
chr5_-_59430600 0.03 ENST00000636120.1
PDE4D
phosphodiesterase 4D
chr2_-_190062721 0.03 ENST00000260950.5
MSTN
myostatin
chr16_+_24537693 0.03 ENST00000564314.5
ENST00000567686.5
RBBP6
RB binding protein 6, ubiquitin ligase
chr5_-_180072086 0.03 ENST00000261947.4
RNF130
ring finger protein 130
chr8_-_69834970 0.03 ENST00000260126.9
SLCO5A1
solute carrier organic anion transporter family member 5A1
chr1_+_67166448 0.03 ENST00000347310.10
IL23R
interleukin 23 receptor
chr21_-_29061351 0.03 ENST00000432178.5
CCT8
chaperonin containing TCP1 subunit 8
chr14_+_50533026 0.03 ENST00000441560.6
ATL1
atlastin GTPase 1
chr4_-_142305826 0.03 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr13_+_77741160 0.03 ENST00000314070.9
ENST00000351546.7
SLAIN1
SLAIN motif family member 1
chr7_-_105269007 0.02 ENST00000357311.7
SRPK2
SRSF protein kinase 2
chr2_+_170178136 0.02 ENST00000409044.7
ENST00000408978.9
MYO3B
myosin IIIB
chr12_+_15956585 0.02 ENST00000526530.1
DERA
deoxyribose-phosphate aldolase
chr5_-_62403506 0.02 ENST00000680062.1
DIMT1
DIMT1 rRNA methyltransferase and ribosome maturation factor
chr20_-_45101112 0.02 ENST00000306117.5
ENST00000537075.3
KCNS1
potassium voltage-gated channel modifier subfamily S member 1
chr6_-_136526472 0.02 ENST00000454590.5
ENST00000432797.6
MAP7
microtubule associated protein 7
chr2_-_174597795 0.02 ENST00000679041.1
WIPF1
WAS/WASL interacting protein family member 1
chr3_-_57292676 0.02 ENST00000389601.3
ENST00000487349.6
ASB14
ankyrin repeat and SOCS box containing 14
chr17_-_75848641 0.02 ENST00000586257.5
WBP2
WW domain binding protein 2
chr14_+_22598224 0.02 ENST00000428304.6
ENST00000542041.1
ENST00000216327.10
ABHD4
abhydrolase domain containing 4, N-acyl phospholipase B
chrX_-_93673558 0.02 ENST00000475430.2
ENST00000373079.4
NAP1L3
nucleosome assembly protein 1 like 3
chr1_+_150067820 0.02 ENST00000419023.3
ENST00000644526.1
VPS45
vacuolar protein sorting 45 homolog
chrX_-_120575783 0.02 ENST00000680673.1
CUL4B
cullin 4B
chr7_-_77798359 0.02 ENST00000257663.4
TMEM60
transmembrane protein 60
chr1_+_197268222 0.02 ENST00000367400.8
ENST00000638467.1
ENST00000367399.6
CRB1
crumbs cell polarity complex component 1
chr1_+_84164962 0.01 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr8_+_49909783 0.01 ENST00000518864.5
SNTG1
syntrophin gamma 1
chr3_-_197260369 0.01 ENST00000658155.1
ENST00000453607.5
DLG1
discs large MAGUK scaffold protein 1
chr3_+_160225409 0.01 ENST00000326474.5
C3orf80
chromosome 3 open reading frame 80
chr13_+_19633642 0.01 ENST00000361479.10
MPHOSPH8
M-phase phosphoprotein 8
chr7_-_137343688 0.01 ENST00000348225.7
PTN
pleiotrophin
chr1_+_150067668 0.01 ENST00000611412.4
ENST00000644510.2
ENST00000643611.1
VPS45
vacuolar protein sorting 45 homolog
chr4_+_70592253 0.01 ENST00000322937.10
ENST00000613447.4
AMBN
ameloblastin
chr6_-_26108125 0.00 ENST00000338379.6
H1-6
H1.6 linker histone, cluster member
chr20_-_10420737 0.00 ENST00000649912.1
ENSG00000285723.1
novel protein
chr10_-_29736956 0.00 ENST00000674475.1
SVIL
supervillin
chr2_-_70248454 0.00 ENST00000416149.6
ENST00000282574.8
TIA1
TIA1 cytotoxic granule associated RNA binding protein
chr2_-_74392025 0.00 ENST00000440727.1
ENST00000409240.5
DCTN1
dynactin subunit 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.2 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.6 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 1.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.2 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.2 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.6 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.4 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.0 GO:0005986 sucrose biosynthetic process(GO:0005986)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.6 GO:0044307 dendritic branch(GO:0044307)
0.1 0.3 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.5 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.2 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.2 GO:0004618 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.1 0.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.5 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 1.1 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones