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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HSF1

Z-value: 0.63

Motif logo

Transcription factors associated with HSF1

Gene Symbol Gene ID Gene Info
ENSG00000185122.11 HSF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF1hg38_v1_chr8_+_144291581_144291617-0.604.1e-04Click!

Activity profile of HSF1 motif

Sorted Z-values of HSF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr20_+_33283205 3.88 ENST00000253354.2
BPI fold containing family B member 1
chr19_-_55160668 3.37 ENST00000588076.1
dynein axonemal assembly factor 3
chr16_+_80540980 3.12 ENST00000568035.5
ENST00000305904.11
dynein light chain roadblock-type 2
chr6_-_32530268 2.62 ENST00000374975.4
major histocompatibility complex, class II, DR beta 5
chr5_+_132294377 2.58 ENST00000200652.4
solute carrier family 22 member 4
chr9_+_124853417 2.17 ENST00000613760.4
ENST00000618744.4
ENST00000373574.2
WD repeat domain 38
chr7_-_99976017 2.09 ENST00000411734.1
ENST00000292401.9
alpha-2-glycoprotein 1, zinc-binding
chr5_+_157269317 1.85 ENST00000618329.4
cytoplasmic FMR1 interacting protein 2
chr12_+_110614027 1.82 ENST00000550703.6
ENST00000551590.5
tectonic family member 1
chr2_+_26401909 1.78 ENST00000288710.7
dynein regulatory complex subunit 1
chr12_+_110614097 1.72 ENST00000471804.7
ENST00000377654.5
ENST00000614115.5
ENST00000397655.7
ENST00000549123.6
ENST00000679401.1
ENST00000397659.9
ENST00000680445.1
tectonic family member 1
chr7_-_123534559 1.69 ENST00000324698.11
IQ motif and ubiquitin domain containing
chr5_-_102296260 1.67 ENST00000310954.7
solute carrier organic anion transporter family member 4C1
chr3_+_42906107 1.65 ENST00000440367.7
ENST00000328199.6
zinc finger protein 662
chr18_-_74147816 1.63 ENST00000419743.7
ENST00000582526.1
F-box protein 15
chr20_+_18813777 1.63 ENST00000377428.4
SCP2 sterol binding domain containing 1
chr21_-_42315336 1.57 ENST00000398431.2
ENST00000518498.3
trefoil factor 3
chr2_-_27628975 1.45 ENST00000324364.4
coiled-coil domain containing 121
chr2_-_237590660 1.37 ENST00000409576.1
RAB17, member RAS oncogene family
chr7_-_138663152 1.36 ENST00000288513.9
SVOP like
chrX_-_72782660 1.36 ENST00000596535.3
family with sequence similarity 236 member B
chr1_-_151372683 1.35 ENST00000458566.5
ENST00000447402.7
ENST00000426705.6
ENST00000368868.10
selenium binding protein 1
chr1_-_60073733 1.27 ENST00000450089.6
chromosome 1 open reading frame 87
chr6_+_32637419 1.25 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr1_-_60073750 1.23 ENST00000371201.3
chromosome 1 open reading frame 87
chr4_-_83109843 1.21 ENST00000411416.6
placenta associated 8
chr19_-_6720641 1.17 ENST00000245907.11
complement C3
chr9_+_72149351 1.15 ENST00000238018.8
guanine deaminase
chr22_+_35381086 1.14 ENST00000216117.9
ENST00000677931.1
ENST00000679074.1
heme oxygenase 1
chr3_-_108222383 1.12 ENST00000264538.4
intraflagellar transport 57
chr6_-_154510114 1.03 ENST00000673182.1
novel protein
chrX_+_72938163 1.00 ENST00000593662.1
ENST00000611003.2
family with sequence similarity 235 member A
chr19_-_4559663 0.98 ENST00000586582.6
semaphorin 6B
chr7_+_107660819 0.97 ENST00000644269.2
solute carrier family 26 member 4
chr5_-_110726649 0.94 ENST00000511883.6
ENST00000455884.7
transmembrane protein 232
chr21_-_7825797 0.94 ENST00000617668.2
potassium voltage-gated channel subfamily E regulatory subunit 1B
chr1_-_113759464 0.94 ENST00000357783.6
ENST00000369604.6
putative homeodomain transcription factor 1
chr3_-_120682215 0.91 ENST00000283871.10
homogentisate 1,2-dioxygenase
chr10_-_114684457 0.91 ENST00000392955.7
actin binding LIM protein 1
chr4_+_54657918 0.89 ENST00000412167.6
ENST00000288135.6
KIT proto-oncogene, receptor tyrosine kinase
chr10_-_114684612 0.89 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr6_+_32637396 0.89 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
major histocompatibility complex, class II, DQ alpha 1
chr22_-_36160773 0.88 ENST00000531095.1
ENST00000349314.6
ENST00000397293.6
apolipoprotein L3
chr18_+_46917561 0.87 ENST00000683218.1
katanin catalytic subunit A1 like 2
chr1_-_173669835 0.87 ENST00000333279.3
ankyrin repeat domain 45
chr3_+_160756225 0.86 ENST00000498165.6
protein phosphatase, Mg2+/Mn2+ dependent 1L
chr7_-_103074725 0.85 ENST00000456695.5
ENST00000455112.6
ENST00000440067.2
F-box and leucine rich repeat protein 13
chr2_+_108786738 0.84 ENST00000412964.6
ENST00000295124.9
coiled-coil domain containing 138
chr10_+_80356754 0.81 ENST00000616870.4
ENST00000411538.5
ENST00000256039.3
DPY30 domain containing 2
chr1_+_47023659 0.81 ENST00000371901.4
cytochrome P450 family 4 subfamily X member 1
chr6_-_46652786 0.80 ENST00000275016.3
ENST00000619708.4
cytochrome P450 family 39 subfamily A member 1
chr9_-_86100123 0.77 ENST00000388711.7
ENST00000466178.1
golgi membrane protein 1
chr10_+_112374110 0.74 ENST00000354655.9
acyl-CoA synthetase long chain family member 5
chr1_+_162381703 0.73 ENST00000458626.4
chromosome 1 open reading frame 226
chr3_-_187736493 0.73 ENST00000232014.8
BCL6 transcription repressor
chr15_-_72197772 0.73 ENST00000309731.12
GRAM domain containing 2A
chr7_+_101085464 0.73 ENST00000306085.11
ENST00000412507.1
tripartite motif containing 56
chr3_-_46464868 0.71 ENST00000417439.5
ENST00000231751.9
ENST00000431944.1
lactotransferrin
chr1_+_212608628 0.70 ENST00000613954.4
ENST00000341491.9
ENST00000366985.5
activating transcription factor 3
chrX_-_72808210 0.69 ENST00000419795.6
ENST00000458170.1
family with sequence similarity 236 member D
chr7_-_5970632 0.69 ENST00000455618.2
ENST00000405415.5
ENST00000404406.5
ENST00000542644.1
radial spoke head 10 homolog B
chr19_+_859654 0.69 ENST00000592860.2
ENST00000327726.11
complement factor D
chr4_+_76011171 0.69 ENST00000513353.5
ENST00000341029.9
ADP-ribosyltransferase 3 (inactive)
chr12_+_93378550 0.68 ENST00000550056.5
ENST00000549992.5
ENST00000548662.5
ENST00000547014.5
nudix hydrolase 4
chr4_+_71187269 0.68 ENST00000425175.5
ENST00000351898.10
solute carrier family 4 member 4
chr7_-_103074816 0.67 ENST00000379305.7
ENST00000379308.7
F-box and leucine rich repeat protein 13
chr6_-_170291053 0.66 ENST00000366756.4
delta like canonical Notch ligand 1
chr14_-_106470788 0.65 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr11_-_26572254 0.65 ENST00000529533.6
mucin 15, cell surface associated
chr11_-_86672419 0.64 ENST00000524826.7
ENST00000532471.1
malic enzyme 3
chr21_+_41361999 0.64 ENST00000436410.5
ENST00000435611.6
ENST00000330714.8
MX dynamin like GTPase 2
chr19_+_47309853 0.64 ENST00000355085.4
complement C5a receptor 1
chr1_+_14929734 0.63 ENST00000376028.8
ENST00000400798.6
kazrin, periplakin interacting protein
chr22_-_28800558 0.62 ENST00000403532.7
ENST00000611155.4
ENST00000216037.10
X-box binding protein 1
chr11_-_26572130 0.62 ENST00000527569.1
mucin 15, cell surface associated
chr3_+_119703001 0.61 ENST00000273390.9
ENST00000463700.1
ENST00000648112.1
cilia and flagella associated protein 91
novel protein
chr19_+_1354931 0.61 ENST00000591337.7
PWWP domain containing 3A, DNA repair factor
chr4_-_25863537 0.61 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr19_+_42302098 0.60 ENST00000598490.1
ENST00000341747.8
proline rich 19
chr16_-_18375069 0.60 ENST00000545114.5
nuclear pore complex interacting protein family, member A9
chr11_-_26572102 0.60 ENST00000455601.6
mucin 15, cell surface associated
chr6_+_31815532 0.59 ENST00000375651.7
ENST00000608703.1
heat shock protein family A (Hsp70) member 1A
chr2_+_27051637 0.57 ENST00000451003.5
ENST00000360131.5
ENST00000323064.12
ATP/GTP binding protein like 5
chr2_+_216659600 0.56 ENST00000456764.1
insulin like growth factor binding protein 2
chr10_+_14959361 0.56 ENST00000407572.6
meiosis/spermiogenesis associated 1
chr19_-_50025936 0.56 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr6_-_53061740 0.56 ENST00000350082.10
ENST00000356971.3
ENST00000676107.1
ciliogenesis associated kinase 1
chr1_+_152663378 0.55 ENST00000368784.2
late cornified envelope 2D
chr4_+_41359599 0.55 ENST00000513024.5
LIM and calponin homology domains 1
chr14_+_75522427 0.53 ENST00000286639.8
basic leucine zipper ATF-like transcription factor
chr1_+_212565334 0.53 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chrX_-_112840815 0.53 ENST00000304758.5
ENST00000371959.9
angiomotin
chr4_+_105895487 0.53 ENST00000506666.5
ENST00000503451.5
nephronectin
chr16_-_75495396 0.52 ENST00000332272.9
carbohydrate sulfotransferase 6
chr11_-_8594181 0.52 ENST00000358872.7
ENST00000454443.2
serine/threonine kinase 33
chr12_+_119334722 0.52 ENST00000327554.3
coiled-coil domain containing 60
chr6_-_28252246 0.51 ENST00000377294.3
zinc finger with KRAB and SCAN domains 4
chr11_-_73142308 0.51 ENST00000409418.9
FCH and double SH3 domains 2
chr22_+_31754862 0.51 ENST00000382111.6
ENST00000645407.1
ENST00000646701.1
DEP domain containing 5, GATOR1 subcomplex subunit
novel protein, DEPDC5-YWHAH readthrough
chr12_-_76348404 0.50 ENST00000650064.2
Bardet-Biedl syndrome 10
chr7_+_150368189 0.50 ENST00000519397.1
ENST00000479668.5
replication initiator 1
chr16_-_46748337 0.50 ENST00000394809.9
myosin light chain kinase 3
chr10_-_80356710 0.49 ENST00000454362.5
ENST00000372204.7
ENST00000372202.6
ENST00000453477.1
DPY30 domain containing 1
chr9_+_33025265 0.49 ENST00000330899.5
DnaJ heat shock protein family (Hsp40) member A1
chr10_-_130110806 0.49 ENST00000637128.2
chromosome 10 open reading frame 143
chr11_+_124115404 0.49 ENST00000361352.9
ENST00000449321.5
ENST00000392748.5
ENST00000392744.4
ENST00000456829.7
von Willebrand factor A domain containing 5A
chr11_-_90223036 0.49 ENST00000320585.11
cysteine and histidine rich domain containing 1
chr4_-_103099811 0.49 ENST00000504285.5
ENST00000296424.9
3-hydroxybutyrate dehydrogenase 2
chr11_-_90223059 0.48 ENST00000457199.6
ENST00000530765.5
cysteine and histidine rich domain containing 1
chr11_+_61752603 0.47 ENST00000278836.10
myelin regulatory factor
chr10_-_60572599 0.47 ENST00000503366.5
ankyrin 3
chr19_-_49808639 0.47 ENST00000529634.2
fuzzy planar cell polarity protein
chr9_-_137028271 0.47 ENST00000265662.9
ENST00000371605.7
ATP binding cassette subfamily A member 2
chr11_-_106022209 0.46 ENST00000301919.9
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT DNA binding domain containing 4 with coiled-coils
chr11_+_10450289 0.46 ENST00000444303.6
adenosine monophosphate deaminase 3
chr15_-_41894049 0.46 ENST00000320955.8
spectrin beta, non-erythrocytic 5
chr6_-_131628060 0.45 ENST00000539158.1
ENST00000368058.5
mediator complex subunit 23
chr19_-_7702124 0.45 ENST00000597921.6
Fc fragment of IgE receptor II
chr1_+_32465046 0.44 ENST00000609129.2
zinc finger and BTB domain containing 8B
chr2_+_85539158 0.44 ENST00000306434.8
methionine adenosyltransferase 2A
chr9_-_34372832 0.44 ENST00000379142.3
myogenesis regulating glycosidase (putative)
chr8_+_8701891 0.44 ENST00000519106.2
claudin 23
chr19_+_11814256 0.43 ENST00000304060.10
ENST00000457526.1
ENST00000427505.5
zinc finger protein 440
chr1_+_27934980 0.42 ENST00000373894.8
sphingomyelin phosphodiesterase acid like 3B
chr14_-_21025000 0.42 ENST00000554489.5
ENST00000555657.5
ENST00000557274.5
ENST00000555158.5
ENST00000554833.5
ENST00000555384.5
ENST00000556420.5
ENST00000554893.5
ENST00000553503.5
ENST00000555733.5
ENST00000397856.7
ENST00000553867.5
ENST00000556147.6
ENST00000556008.5
ENST00000557182.5
ENST00000554483.5
ENST00000556688.5
ENST00000397853.7
ENST00000556329.6
ENST00000397851.6
ENST00000554143.5
ENST00000555142.5
ENST00000557676.5
ENST00000556924.5
NDRG family member 2
chr9_-_94593810 0.42 ENST00000375337.4
fructose-bisphosphatase 2
chr11_-_86672630 0.42 ENST00000543262.5
malic enzyme 3
chr6_+_31827730 0.42 ENST00000375650.5
heat shock protein family A (Hsp70) member 1B
chr21_-_41926680 0.41 ENST00000329623.11
C2 calcium dependent domain containing 2
chr1_+_46340780 0.40 ENST00000474844.6
NOP2/Sun RNA methyltransferase 4
chr7_-_152435786 0.40 ENST00000682283.1
ENST00000679882.1
ENST00000452749.2
ENST00000683616.1
ENST00000262189.11
ENST00000683490.1
ENST00000681082.1
ENST00000684550.1
lysine methyltransferase 2C
chr1_+_27935110 0.40 ENST00000549094.1
sphingomyelin phosphodiesterase acid like 3B
chr19_-_54364807 0.39 ENST00000474878.5
leukocyte associated immunoglobulin like receptor 1
chr19_-_7702139 0.39 ENST00000346664.9
Fc fragment of IgE receptor II
chr20_-_45827297 0.39 ENST00000372555.8
troponin C2, fast skeletal type
chr9_+_72149424 0.39 ENST00000358399.8
ENST00000376986.5
guanine deaminase
chr17_+_7705193 0.39 ENST00000226091.3
ephrin B3
chr1_+_152675295 0.39 ENST00000368783.1
late cornified envelope 2C
chr2_-_200864561 0.39 ENST00000434813.3
CDC like kinase 1
chr2_+_232662733 0.39 ENST00000410095.5
ENST00000611312.1
EF-hand domain family member D1
chr21_+_43728851 0.39 ENST00000327574.4
pyridoxal kinase
chr2_+_102473219 0.39 ENST00000295269.5
solute carrier family 9 member A4
chrX_-_48919015 0.38 ENST00000376509.4
Pim-2 proto-oncogene, serine/threonine kinase
chr12_-_54648356 0.38 ENST00000293371.11
ENST00000456047.2
dermcidin
chr14_-_102087034 0.38 ENST00000216281.13
ENST00000553585.5
heat shock protein 90 alpha family class A member 1
chr8_-_55773295 0.38 ENST00000523423.5
ENST00000523073.5
ENST00000519784.5
ENST00000519780.5
ENST00000521229.5
ENST00000434581.7
ENST00000522576.5
ENST00000523180.5
ENST00000522090.5
transmembrane protein 68
chr6_-_131628165 0.38 ENST00000368053.8
ENST00000354577.8
ENST00000368060.7
ENST00000368068.8
mediator complex subunit 23
chr17_+_7687416 0.37 ENST00000457584.6
WD repeat containing antisense to TP53
chr9_-_113340248 0.37 ENST00000341761.8
ENST00000374195.7
ENST00000374193.9
WD repeat domain 31
chr1_+_166989254 0.37 ENST00000367872.9
ENST00000447624.1
maelstrom spermatogenic transposon silencer
chr17_+_50834581 0.36 ENST00000426127.1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr5_+_179023794 0.36 ENST00000519896.5
ENST00000522442.1
ENST00000444149.7
zinc finger protein 879
chr10_-_51699559 0.36 ENST00000331173.6
cleavage stimulation factor subunit 2 tau variant
chr12_+_6789508 0.36 ENST00000011653.9
ENST00000541982.5
ENST00000539492.1
CD4 molecule
chr3_+_93980130 0.36 ENST00000535334.5
ENST00000681380.1
ENST00000303097.11
ENST00000486562.2
ENST00000471138.5
ENST00000394222.8
ENST00000679872.1
ENST00000679404.1
ENST00000681655.1
ENST00000679657.1
ENST00000679666.1
ADP ribosylation factor like GTPase 13B
chr1_+_166989089 0.35 ENST00000367870.6
maelstrom spermatogenic transposon silencer
chr9_-_86099506 0.35 ENST00000388712.7
golgi membrane protein 1
chr3_+_93980203 0.35 ENST00000679607.1
ENST00000679587.1
ADP ribosylation factor like GTPase 13B
chr19_-_54364983 0.34 ENST00000434277.6
leukocyte associated immunoglobulin like receptor 1
chr1_+_151036578 0.34 ENST00000368931.8
ENST00000295294.11
BCL2 interacting protein like
chr19_+_3708378 0.34 ENST00000541714.7
ENST00000539908.6
tight junction protein 3
chr18_+_13465009 0.33 ENST00000593236.1
ENST00000678400.1
low density lipoprotein receptor class A domain containing 4
chr11_-_107457801 0.33 ENST00000282251.9
CWF19 like cell cycle control factor 2
chr2_+_189857393 0.33 ENST00000452382.1
PMS1 homolog 1, mismatch repair system component
chr1_-_10796636 0.32 ENST00000377022.8
ENST00000344008.5
castor zinc finger 1
chr2_-_55923775 0.32 ENST00000438672.5
ENST00000355426.8
ENST00000440439.5
ENST00000429909.5
ENST00000424207.5
ENST00000452337.5
ENST00000439193.5
ENST00000421664.1
EGF containing fibulin extracellular matrix protein 1
chr19_-_54364908 0.31 ENST00000391742.7
leukocyte associated immunoglobulin like receptor 1
chr2_-_218002988 0.31 ENST00000682258.1
ENST00000446903.5
tensin 1
chr5_-_140673568 0.31 ENST00000542735.2
DND microRNA-mediated repression inhibitor 1
chr22_-_44498179 0.31 ENST00000341255.4
retrotransposon Gag like 6
chr19_-_50025327 0.31 ENST00000594092.5
ENST00000594948.5
ENST00000316763.8
ENST00000377011.6
ENST00000593919.5
ENST00000601324.1
ENST00000601341.5
ENST00000600259.5
VRK serine/threonine kinase 3
chr6_-_159000174 0.31 ENST00000367069.7
radial spoke head 3
chr19_-_54364863 0.31 ENST00000348231.8
leukocyte associated immunoglobulin like receptor 1
chr11_+_61755372 0.31 ENST00000265460.9
myelin regulatory factor
chr11_-_132943092 0.31 ENST00000612177.4
ENST00000541867.5
opioid binding protein/cell adhesion molecule like
chr9_-_137028878 0.30 ENST00000625103.1
ENST00000614293.4
ATP binding cassette subfamily A member 2
chr2_+_102008515 0.29 ENST00000441002.1
interleukin 1 receptor type 2
chr17_-_35986649 0.29 ENST00000622526.1
ENST00000620991.1
ENST00000618404.5
C-C motif chemokine ligand 14
chr17_+_4731410 0.29 ENST00000575284.5
ENST00000293777.6
ENST00000674339.1
ENST00000573708.1
mediator complex subunit 11
chr2_+_240625237 0.29 ENST00000407714.1
G protein-coupled receptor 35
chr17_+_31391645 0.29 ENST00000621161.5
RAB11 family interacting protein 4
chr3_-_39192584 0.29 ENST00000340369.4
ENST00000421646.1
ENST00000396251.1
xin actin binding repeat containing 1
chr4_+_75556048 0.29 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
odontogenesis associated phosphoprotein
chr9_-_127905313 0.28 ENST00000622357.5
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr7_+_5879827 0.28 ENST00000416608.5
oncomodulin
chr2_+_47369301 0.28 ENST00000263735.9
epithelial cell adhesion molecule
chr18_+_13611764 0.28 ENST00000585931.5
low density lipoprotein receptor class A domain containing 4
chr3_+_130894050 0.28 ENST00000510168.6
ATPase secretory pathway Ca2+ transporting 1
chr8_+_19313685 0.28 ENST00000265807.8
ENST00000518040.5
SH2 domain containing 4A
chr3_-_51499950 0.28 ENST00000423656.5
ENST00000504652.5
ENST00000684031.1
DDB1 and CUL4 associated factor 1
chr1_+_21551260 0.27 ENST00000374832.5
alkaline phosphatase, biomineralization associated
chr20_-_32483438 0.27 ENST00000359676.9
nucleolar protein 4 like
chr17_+_76000906 0.27 ENST00000448471.2
cyclin dependent kinase 3
chr12_+_93378625 0.27 ENST00000546925.1
nudix hydrolase 4
chrX_-_72305892 0.27 ENST00000450875.5
ENST00000417400.1
ENST00000431381.5
ENST00000445983.5
ENST00000651998.1
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr1_-_27356471 0.27 ENST00000486046.5
mitogen-activated protein kinase kinase kinase 6
chr19_+_35448251 0.27 ENST00000599180.3
free fatty acid receptor 2
chrX_+_109536641 0.27 ENST00000372107.5
nuclear transport factor 2 like export factor 2
chr10_+_129467178 0.27 ENST00000306010.8
ENST00000651593.1
O-6-methylguanine-DNA methyltransferase
chr6_-_31815244 0.26 ENST00000375654.5
heat shock protein family A (Hsp70) member 1 like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.5 1.5 GO:0006147 guanine catabolic process(GO:0006147)
0.5 1.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.4 1.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.4 1.2 GO:0002892 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.4 1.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.3 1.0 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.3 1.2 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.3 0.9 GO:0070662 erythropoietin-mediated signaling pathway(GO:0038162) mast cell proliferation(GO:0070662)
0.3 3.9 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.3 0.8 GO:0030573 bile acid catabolic process(GO:0030573)
0.2 0.7 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.2 0.7 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.2 0.6 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.2 1.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 0.6 GO:0035470 positive regulation of vascular wound healing(GO:0035470) regulation of lactation(GO:1903487)
0.2 0.7 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.2 0.7 GO:0044407 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) positive regulation of chondrocyte proliferation(GO:1902732)
0.2 0.5 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.2 1.0 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 5.2 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 1.1 GO:0015705 iodide transport(GO:0015705)
0.1 2.6 GO:0009437 carnitine metabolic process(GO:0009437)
0.1 1.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.8 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 0.5 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.5 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 1.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.8 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.5 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.4 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.5 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.4 GO:0043335 protein unfolding(GO:0043335)
0.1 0.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.3 GO:0071529 cementum mineralization(GO:0071529)
0.1 0.3 GO:0016116 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.1 0.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.6 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.8 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 4.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.5 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.3 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.1 GO:0016068 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
0.1 0.4 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1 0.6 GO:0035973 aggrephagy(GO:0035973)
0.1 0.7 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.1 0.3 GO:0070672 response to interleukin-15(GO:0070672)
0.1 0.2 GO:0018032 protein amidation(GO:0018032)
0.1 0.2 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.1 0.2 GO:0019605 butyrate metabolic process(GO:0019605)
0.1 0.2 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 2.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.6 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.2 GO:0071110 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
0.1 0.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) negative regulation of cholesterol efflux(GO:0090370) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.4 GO:0032202 telomere assembly(GO:0032202)
0.0 1.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.2 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 1.0 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.3 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 5.2 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.5 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.5 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:0035922 pulmonary valve formation(GO:0003193) foramen ovale closure(GO:0035922)
0.0 0.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.4 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.6 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.5 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.1 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.5 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.8 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.4 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.4 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.6 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.1 GO:1901142 insulin metabolic process(GO:1901142)
0.0 0.2 GO:0009838 abscission(GO:0009838)
0.0 1.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.3 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.0 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.0 0.1 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.2 GO:0045076 regulation of interleukin-2 biosynthetic process(GO:0045076)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.2 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.3 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.0 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 1.1 GO:0015914 phospholipid transport(GO:0015914)
0.0 3.3 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 3.2 GO:0036157 outer dynein arm(GO:0036157)
0.2 0.7 GO:0030849 autosome(GO:0030849)
0.2 4.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 3.5 GO:0036038 MKS complex(GO:0036038)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.7 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.1 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 1.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.0 1.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 2.3 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 1.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0001940 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 1.7 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.0 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0008513 secondary active organic cation transmembrane transporter activity(GO:0008513)
0.5 1.5 GO:0008892 guanine deaminase activity(GO:0008892)
0.2 1.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 1.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.6 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.2 0.7 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 0.8 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 0.5 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 1.0 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.4 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 1.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 3.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 1.0 GO:0019863 IgE binding(GO:0019863)
0.1 0.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.3 GO:0008430 selenium binding(GO:0008430)
0.1 2.1 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 0.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.4 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.1 0.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 2.6 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.2 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.2 GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0047315 kynurenine-glyoxylate transaminase activity(GO:0047315)
0.0 0.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.3 GO:0009008 S-methyltransferase activity(GO:0008172) DNA-methyltransferase activity(GO:0009008)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 0.8 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 3.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.9 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.7 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 1.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions