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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HSF4

Z-value: 0.41

Motif logo

Transcription factors associated with HSF4

Gene Symbol Gene ID Gene Info
ENSG00000102878.18 HSF4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF4hg38_v1_chr16_+_67164730_671647680.193.0e-01Click!

Activity profile of HSF4 motif

Sorted Z-values of HSF4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_-_76141240 1.74 ENST00000322957.7
forkhead box J1
chr9_-_135499846 1.59 ENST00000429260.7
chromosome 9 open reading frame 116
chr18_-_74147816 1.52 ENST00000419743.7
ENST00000582526.1
F-box protein 15
chr19_-_55160668 1.43 ENST00000588076.1
dynein axonemal assembly factor 3
chr1_-_60073733 1.13 ENST00000450089.6
chromosome 1 open reading frame 87
chr1_-_60073750 1.12 ENST00000371201.3
chromosome 1 open reading frame 87
chr1_-_173669835 0.79 ENST00000333279.3
ankyrin repeat domain 45
chr18_+_46917561 0.74 ENST00000683218.1
katanin catalytic subunit A1 like 2
chr5_+_141223332 0.70 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
protocadherin beta 14
novel protein
chr13_-_31161927 0.69 ENST00000380405.7
heat shock protein family H (Hsp110) member 1
chr9_+_72149351 0.64 ENST00000238018.8
guanine deaminase
chr13_-_31161890 0.64 ENST00000320027.10
heat shock protein family H (Hsp110) member 1
chr2_-_237590660 0.64 ENST00000409576.1
RAB17, member RAS oncogene family
chr11_-_123062022 0.62 ENST00000532182.5
ENST00000524590.5
ENST00000528292.5
ENST00000533540.5
ENST00000534624.6
ENST00000525463.5
heat shock protein family A (Hsp70) member 8
chr11_-_123062335 0.62 ENST00000453788.6
ENST00000527387.5
heat shock protein family A (Hsp70) member 8
chr1_-_26306576 0.62 ENST00000421827.2
ENST00000374215.5
ENST00000374223.5
ENST00000357089.8
ENST00000314675.11
ENST00000423664.5
ENST00000374221.7
UBX domain protein 11
chr20_-_36951701 0.61 ENST00000646673.2
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr20_-_36951837 0.57 ENST00000262878.5
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr19_-_6720641 0.56 ENST00000245907.11
complement C3
chr1_+_26921715 0.56 ENST00000321265.10
nuclear distribution C, dynein complex regulator
chr1_+_212608628 0.55 ENST00000613954.4
ENST00000341491.9
ENST00000366985.5
activating transcription factor 3
chr20_-_36951637 0.54 ENST00000646066.1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr13_-_31162341 0.52 ENST00000445273.6
ENST00000630972.2
heat shock protein family H (Hsp110) member 1
chr16_-_18375069 0.52 ENST00000545114.5
nuclear pore complex interacting protein family, member A9
chr20_-_36951665 0.52 ENST00000643918.1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr15_+_78264552 0.51 ENST00000394852.8
ENST00000343789.7
DnaJ heat shock protein family (Hsp40) member A4
chr9_+_33025265 0.51 ENST00000330899.5
DnaJ heat shock protein family (Hsp40) member A1
chr4_+_76011171 0.50 ENST00000513353.5
ENST00000341029.9
ADP-ribosyltransferase 3 (inactive)
chr14_-_102087034 0.48 ENST00000216281.13
ENST00000553585.5
heat shock protein 90 alpha family class A member 1
chr19_+_1354931 0.43 ENST00000591337.7
PWWP domain containing 3A, DNA repair factor
chr16_-_9943182 0.43 ENST00000535259.6
glutamate ionotropic receptor NMDA type subunit 2A
chr11_-_90223036 0.42 ENST00000320585.11
cysteine and histidine rich domain containing 1
chr11_-_90223059 0.42 ENST00000457199.6
ENST00000530765.5
cysteine and histidine rich domain containing 1
chr19_-_51390528 0.40 ENST00000570516.1
ENST00000574814.2
chromosome 19 open reading frame 84
chr7_-_56051544 0.39 ENST00000395471.7
phosphoserine phosphatase
chr10_-_60572599 0.38 ENST00000503366.5
ankyrin 3
chr3_+_101724602 0.37 ENST00000341893.8
centrosomal protein 97
chr7_-_56051288 0.37 ENST00000419984.6
ENST00000413218.5
ENST00000275605.8
ENST00000424596.1
ENST00000421312.5
ENST00000416592.1
phosphoserine phosphatase
chr4_-_25863537 0.35 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr15_+_41660397 0.30 ENST00000219905.12
ENST00000566586.6
MAX dimerization protein MGA
chr9_-_86100123 0.30 ENST00000388711.7
ENST00000466178.1
golgi membrane protein 1
chr11_+_112175501 0.29 ENST00000357685.11
ENST00000361053.8
beta-carotene oxygenase 2
chr4_+_41359599 0.27 ENST00000513024.5
LIM and calponin homology domains 1
chr5_-_10249876 0.27 ENST00000511437.6
ENST00000280330.12
ENST00000510047.5
ATP synthase c subunit lysine N-methyltransferase
chr11_+_112175526 0.27 ENST00000532612.5
ENST00000438022.5
beta-carotene oxygenase 2
chr2_+_85539158 0.26 ENST00000306434.8
methionine adenosyltransferase 2A
chr9_+_72149424 0.26 ENST00000358399.8
ENST00000376986.5
guanine deaminase
chr19_+_859654 0.24 ENST00000592860.2
ENST00000327726.11
complement factor D
chr8_+_37736667 0.23 ENST00000518586.5
ENST00000335171.10
ENST00000521644.5
ER lipid raft associated 2
chr10_+_129467178 0.22 ENST00000306010.8
ENST00000651593.1
O-6-methylguanine-DNA methyltransferase
chr9_-_86099506 0.22 ENST00000388712.7
golgi membrane protein 1
chr20_-_44960348 0.22 ENST00000372813.4
translocase of outer mitochondrial membrane 34
chr6_-_76072654 0.21 ENST00000369950.8
ENST00000611179.4
ENST00000369963.5
interphotoreceptor matrix proteoglycan 1
chr1_-_244863085 0.21 ENST00000440865.2
heterogeneous nuclear ribonucleoprotein U
chr20_+_18813777 0.20 ENST00000377428.4
SCP2 sterol binding domain containing 1
chr2_-_68952880 0.20 ENST00000481498.1
ENST00000328895.9
gastrokine 2
chr15_+_43800586 0.20 ENST00000442995.4
ENST00000458412.2
huntingtin interacting protein K
chr6_+_44247866 0.20 ENST00000371554.2
heat shock protein 90 alpha family class B member 1
chr4_-_158723355 0.19 ENST00000307720.4
peptidylprolyl isomerase D
chr11_-_86672419 0.19 ENST00000524826.7
ENST00000532471.1
malic enzyme 3
chr16_-_23557331 0.18 ENST00000563232.1
ENST00000449606.7
glutamyl-tRNA synthetase 2, mitochondrial
chr1_+_44213440 0.18 ENST00000361745.10
ENST00000446292.5
ENST00000440641.5
ENST00000372289.7
ENST00000436069.5
ENST00000437511.5
DNA methyltransferase 1 associated protein 1
chr1_+_44213487 0.18 ENST00000315913.9
DNA methyltransferase 1 associated protein 1
chr18_+_9136757 0.17 ENST00000262126.9
ENST00000577992.1
ankyrin repeat domain 12
chr8_+_142834801 0.17 ENST00000220940.2
glycosylphosphatidylinositol anchored molecule like
chr3_+_96814552 0.16 ENST00000470610.6
ENST00000389672.9
EPH receptor A6
chr15_+_96325935 0.15 ENST00000421109.6
nuclear receptor subfamily 2 group F member 2
chr1_-_156282799 0.15 ENST00000361813.5
SMG5 nonsense mediated mRNA decay factor
chr10_-_20897288 0.14 ENST00000377122.9
nebulette
chr6_+_127577168 0.14 ENST00000329722.8
chromosome 6 open reading frame 58
chr21_+_42974510 0.14 ENST00000432907.6
ENST00000291547.10
PBX/knotted 1 homeobox 1
chr18_-_46917432 0.14 ENST00000324794.11
ENST00000545673.5
ENST00000585916.6
protein inhibitor of activated STAT 2
chr22_+_29268248 0.14 ENST00000436425.5
ENST00000447973.5
ENST00000397938.7
ENST00000406548.5
ENST00000437155.6
ENST00000415761.5
ENST00000331029.11
EWS RNA binding protein 1
chr1_+_149782671 0.14 ENST00000444948.5
ENST00000369168.5
Fc fragment of IgG receptor Ia
chr18_+_13465009 0.14 ENST00000593236.1
ENST00000678400.1
low density lipoprotein receptor class A domain containing 4
chr11_+_193078 0.14 ENST00000342878.3
secretoglobin family 1C member 1
chr5_+_10250272 0.13 ENST00000280326.9
ENST00000625723.1
chaperonin containing TCP1 subunit 5
chr1_+_154993581 0.13 ENST00000392487.1
lens epithelial protein
chrX_-_153724343 0.13 ENST00000442093.5
ENST00000345046.12
ENST00000645377.1
ENST00000672675.1
ENST00000647529.1
ENST00000429550.5
B cell receptor associated protein 31
chr14_-_23071538 0.12 ENST00000555566.1
ENST00000338631.10
ENST00000557515.5
ENST00000397341.7
apoptotic chromatin condensation inducer 1
chr16_-_8861799 0.12 ENST00000610831.4
ENST00000614449.4
calcium regulated heat stable protein 1
chr18_+_59899988 0.12 ENST00000316660.7
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr5_-_140673568 0.12 ENST00000542735.2
DND microRNA-mediated repression inhibitor 1
chr21_-_39349048 0.12 ENST00000380748.5
ENST00000380749.10
high mobility group nucleosome binding domain 1
chr5_+_134371561 0.12 ENST00000265339.7
ENST00000506787.5
ENST00000507277.1
ubiquitin conjugating enzyme E2 B
chr11_-_111910830 0.12 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr11_-_111910790 0.12 ENST00000533280.6
crystallin alpha B
chr13_-_30617500 0.11 ENST00000405805.5
high mobility group box 1
chr2_-_47906437 0.11 ENST00000403359.8
F-box protein 11
chr11_+_64186163 0.11 ENST00000305218.9
ENST00000538945.5
stress induced phosphoprotein 1
chr5_+_57174016 0.11 ENST00000514387.6
ENST00000506184.7
GC-rich promoter binding protein 1
chr11_-_111910888 0.11 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr11_-_47848467 0.11 ENST00000378460.6
nucleoporin 160
chr3_+_130894050 0.11 ENST00000510168.6
ATPase secretory pathway Ca2+ transporting 1
chr17_-_63773534 0.11 ENST00000403162.7
ENST00000582252.1
ENST00000225726.10
coiled-coil domain containing 47
chr20_+_19886506 0.11 ENST00000648440.1
Ras and Rab interactor 2
chr22_+_40857076 0.10 ENST00000614001.1
ENST00000357137.9
X-prolyl aminopeptidase 3
chr13_-_41019289 0.10 ENST00000239882.7
E74 like ETS transcription factor 1
chr11_+_10751203 0.10 ENST00000361367.7
CTR9 homolog, Paf1/RNA polymerase II complex component
chr14_+_63204436 0.10 ENST00000316754.8
ras homolog family member J
chrX_-_103093109 0.10 ENST00000395065.8
nuclear RNA export factor 3
chrX_-_103688033 0.10 ENST00000434230.5
ENST00000418819.5
ENST00000360458.5
mortality factor 4 like 2
chr11_+_107928394 0.10 ENST00000320578.3
RAB39A, member RAS oncogene family
chr15_-_85794902 0.10 ENST00000337975.6
kelch like family member 25
chr20_+_37521206 0.10 ENST00000346199.3
ENST00000647955.1
ENST00000649451.1
ENST00000649697.1
ENST00000649309.1
neuronatin
chrX_-_155334580 0.10 ENST00000369449.7
ENST00000321926.4
chloride intracellular channel 2
chr14_-_22919124 0.10 ENST00000555209.5
ENST00000554256.5
ENST00000557403.5
ENST00000359890.8
ENST00000557549.5
ENST00000555676.5
ENST00000557571.5
ENST00000557464.5
ENST00000554618.5
ENST00000556862.5
ENST00000555722.5
ENST00000346528.9
ENST00000542016.6
ENST00000399922.6
ENST00000557227.5
RNA binding motif protein 23
chr3_+_45026296 0.09 ENST00000296130.5
C-type lectin domain family 3 member B
chr2_+_197500371 0.09 ENST00000409468.1
ENST00000233893.10
heat shock protein family E (Hsp10) member 1
chr5_-_134371004 0.09 ENST00000521755.1
ENST00000523054.5
ENST00000518409.1
cyclin dependent kinase like 3
novel transcript
chr18_+_13611764 0.09 ENST00000585931.5
low density lipoprotein receptor class A domain containing 4
chr7_+_56051756 0.09 ENST00000275603.9
chaperonin containing TCP1 subunit 6A
chr12_+_48727431 0.08 ENST00000548380.6
testis expressed 49
chr13_+_30617902 0.08 ENST00000255304.9
ENST00000614860.1
ubiquitin specific peptidase like 1
chr12_-_48682158 0.08 ENST00000553086.5
ENST00000548304.1
ENST00000550347.5
ENST00000420613.7
ENST00000550931.5
ENST00000550870.1
KAT8 regulatory NSL complex subunit 2
chr1_+_196888014 0.08 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
complement factor H related 4
chr1_+_156338455 0.08 ENST00000368253.6
ENST00000470342.5
ENST00000368254.6
TSSK6 activating cochaperone
chr11_-_27700472 0.08 ENST00000418212.5
ENST00000533246.5
brain derived neurotrophic factor
chr11_-_47848313 0.08 ENST00000530326.5
ENST00000528071.5
nucleoporin 160
chr2_-_208124514 0.07 ENST00000264376.5
crystallin gamma D
chr4_-_94342826 0.07 ENST00000295256.10
hematopoietic prostaglandin D synthase
chr19_+_49851205 0.07 ENST00000601675.5
PTOV1 extended AT-hook containing adaptor protein
chr6_+_44246166 0.07 ENST00000620073.4
heat shock protein 90 alpha family class B member 1
chr2_+_202265721 0.07 ENST00000264279.10
NOP58 ribonucleoprotein
chr20_-_23750929 0.07 ENST00000304749.7
cystatin SN
chr1_+_65309517 0.07 ENST00000371069.5
DnaJ heat shock protein family (Hsp40) member C6
chr1_-_53238485 0.07 ENST00000371466.4
ENST00000371470.8
mago homolog, exon junction complex subunit
chr9_-_13279407 0.06 ENST00000546205.5
multiple PDZ domain crumbs cell polarity complex component
chr20_-_23688951 0.06 ENST00000217423.4
cystatin S
chr7_+_56051685 0.06 ENST00000335503.3
chaperonin containing TCP1 subunit 6A
chr19_+_49851136 0.06 ENST00000391842.5
PTOV1 extended AT-hook containing adaptor protein
chr19_+_49851173 0.06 ENST00000599732.5
PTOV1 extended AT-hook containing adaptor protein
chr1_+_121087343 0.06 ENST00000616817.4
ENST00000623603.3
ENST00000369384.9
ENST00000369383.8
ENST00000369178.5
Fc fragment of IgG receptor Ib
chr22_+_29268316 0.06 ENST00000414183.6
ENST00000333395.10
ENST00000455726.5
ENST00000332035.10
EWS RNA binding protein 1
chr11_+_66002754 0.06 ENST00000527348.1
BAF nuclear assembly factor 1
chr11_+_76381303 0.06 ENST00000662483.1
ENST00000663165.1
ENST00000529331.2
ENST00000321844.6
ENST00000667240.1
GVQW motif containing 3
chr19_+_2269520 0.06 ENST00000602676.6
ENST00000582888.8
ornithine decarboxylase antizyme 1
chr11_+_64186219 0.05 ENST00000543847.1
stress induced phosphoprotein 1
chr4_-_83485065 0.05 ENST00000515303.2
ENST00000321945.12
ENST00000503217.2
abraxas 1, BRCA1 A complex subunit
chr21_+_43728851 0.05 ENST00000327574.4
pyridoxal kinase
chr2_+_197500398 0.05 ENST00000604458.1
HSPE1-MOB4 readthrough
chr1_+_156338619 0.05 ENST00000481479.5
ENST00000368252.5
ENST00000466306.5
ENST00000368251.1
TSSK6 activating cochaperone
chr18_-_21704763 0.05 ENST00000580981.5
ENST00000289119.7
abhydrolase domain containing 3, phospholipase
chr12_-_76423256 0.05 ENST00000546946.5
oxysterol binding protein like 8
chrX_-_103688090 0.05 ENST00000433176.6
mortality factor 4 like 2
chr17_+_137569 0.05 ENST00000595228.4
secretoglobin family 1C member 2
chr11_+_66002225 0.05 ENST00000445560.6
ENST00000530204.1
BAF nuclear assembly factor 1
chr8_+_37736612 0.05 ENST00000518526.5
ENST00000523887.5
ENST00000648919.1
ENST00000519638.3
ER lipid raft associated 2
chr8_-_27614681 0.05 ENST00000519472.5
ENST00000523589.5
ENST00000522413.5
ENST00000523396.1
ENST00000316403.15
clusterin
chr12_-_9733292 0.05 ENST00000621400.4
ENST00000327839.3
C-type lectin like 1
chr11_+_67240047 0.05 ENST00000530342.2
lysine demethylase 2A
chr12_+_65169546 0.05 ENST00000308330.3
LEM domain containing 3
chr19_+_52274443 0.04 ENST00000600821.5
ENST00000595149.5
ENST00000595000.5
ENST00000593612.1
zinc finger protein 766
chr19_+_41003946 0.04 ENST00000593831.1
cytochrome P450 family 2 subfamily B member 6
chr2_-_68252482 0.04 ENST00000234310.8
protein phosphatase 3 regulatory subunit B, alpha
chr3_+_1093002 0.04 ENST00000446702.7
contactin 6
chr12_+_110502200 0.04 ENST00000409246.5
ENST00000392672.8
ENST00000409425.5
RAD9 checkpoint clamp component B
chr20_-_23751256 0.04 ENST00000398402.1
cystatin SN
chr14_-_23071617 0.04 ENST00000357481.6
apoptotic chromatin condensation inducer 1
chr3_+_133400046 0.04 ENST00000302334.3
beaded filament structural protein 2
chr12_+_110502307 0.04 ENST00000409778.7
ENST00000409300.6
RAD9 checkpoint clamp component B
chr20_+_63658286 0.04 ENST00000360203.11
ENST00000508582.7
ENST00000318100.9
ENST00000356810.5
regulator of telomere elongation helicase 1
chr17_+_34319427 0.04 ENST00000394620.2
C-C motif chemokine ligand 8
chr1_-_228425350 0.03 ENST00000366696.2
H3.4 histone
chr7_+_5879827 0.03 ENST00000416608.5
oncomodulin
chr2_-_197499857 0.03 ENST00000428204.6
ENST00000678170.1
ENST00000676933.1
ENST00000678621.1
heat shock protein family D (Hsp60) member 1
chr3_+_186783567 0.03 ENST00000323963.10
ENST00000440191.6
eukaryotic translation initiation factor 4A2
chr17_+_35760881 0.03 ENST00000605587.2
ENST00000604830.1
chromosome 17 open reading frame 50
chr19_+_6135635 0.03 ENST00000588304.5
ENST00000588722.5
ENST00000588485.6
ENST00000591403.5
ENST00000586696.5
ENST00000681525.1
ENST00000589401.5
acyl-CoA synthetase bubblegum family member 2
chr11_+_66002475 0.03 ENST00000312175.7
ENST00000533166.5
BAF nuclear assembly factor 1
chr2_-_197499826 0.03 ENST00000439605.2
ENST00000388968.8
ENST00000418022.2
heat shock protein family D (Hsp60) member 1
chr17_-_42016680 0.03 ENST00000674497.1
DnaJ heat shock protein family (Hsp40) member C7
chrX_+_109536641 0.03 ENST00000372107.5
nuclear transport factor 2 like export factor 2
chrX_-_154292117 0.03 ENST00000610938.1
testis expressed 28
chr16_-_8861713 0.03 ENST00000567554.5
calcium regulated heat stable protein 1
chr15_+_78872881 0.02 ENST00000559930.5
ENST00000426013.7
mortality factor 4 like 1
chr3_+_138347648 0.02 ENST00000614350.4
ENST00000289104.8
muscle RAS oncogene homolog
chr3_-_42410558 0.02 ENST00000441172.1
ENST00000287748.8
lysozyme like 4
chr11_-_10568571 0.02 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr11_-_111911759 0.02 ENST00000650687.2
crystallin alpha B
chrX_+_109536832 0.02 ENST00000372106.6
nuclear transport factor 2 like export factor 2
chr8_-_88327475 0.02 ENST00000286614.11
matrix metallopeptidase 16
chr16_+_29778252 0.02 ENST00000400752.6
zymogen granule protein 16
chr7_+_157336961 0.02 ENST00000429029.6
DnaJ heat shock protein family (Hsp40) member B6
chr8_-_119592954 0.02 ENST00000522167.5
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr15_+_78872809 0.02 ENST00000331268.9
mortality factor 4 like 1
chr9_-_83978429 0.02 ENST00000351839.7
heterogeneous nuclear ribonucleoprotein K
chr11_-_10568650 0.02 ENST00000256178.8
lymphatic vessel endothelial hyaluronan receptor 1
chr1_-_182400660 0.02 ENST00000367565.2
transmembrane epididymal protein 1
chr16_-_8861744 0.01 ENST00000569398.5
ENST00000568968.1
calcium regulated heat stable protein 1
chr19_-_42217667 0.01 ENST00000336034.8
ENST00000596251.6
ENST00000598200.1
ENST00000598727.5
death effector domain containing 2
chr15_-_58065870 0.01 ENST00000537372.5
aldehyde dehydrogenase 1 family member A2
chr8_+_61287950 0.01 ENST00000519846.5
ENST00000325897.5
ENST00000523868.2
ENST00000518592.5
clavesin 1
chrX_-_140784366 0.01 ENST00000674533.1
cerebellar degeneration related protein 1
chr11_+_124622853 0.01 ENST00000441174.8
ENST00000531667.5
transforming growth factor beta regulator 1
chr12_+_2794961 0.01 ENST00000001008.6
FKBP prolyl isomerase 4
chr9_-_135699473 0.01 ENST00000425225.2
ENST00000298466.9
spermatogenesis and oogenesis specific basic helix-loop-helix 1
chr5_+_446139 0.00 ENST00000315013.9
exocyst complex component 3
chr12_+_103587266 0.00 ENST00000388887.7
stabilin 2
chrX_+_123961304 0.00 ENST00000371160.5
ENST00000435103.5
stromal antigen 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0006147 guanine catabolic process(GO:0006147)
0.3 0.8 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.3 2.2 GO:0046061 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.3 1.9 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.2 1.2 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.2 1.7 GO:0035502 metanephric part of ureteric bud development(GO:0035502) negative regulation of interleukin-6 biosynthetic process(GO:0045409) glomerular parietal epithelial cell differentiation(GO:0072139)
0.2 0.6 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 0.6 GO:0002892 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.2 0.6 GO:0016116 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.2 0.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.5 GO:0043335 protein unfolding(GO:0043335)
0.1 0.4 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:1901389 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.1 0.4 GO:0033058 directional locomotion(GO:0033058)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.5 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 1.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.3 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903)
0.0 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.2 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:1904851 positive regulation of establishment of protein localization to telomere(GO:1904851)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 1.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.3 GO:1990913 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 2.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0008832 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567)
0.3 0.9 GO:0008892 guanine deaminase activity(GO:0008892)
0.2 1.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 0.8 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 1.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.3 GO:0002135 CTP binding(GO:0002135)
0.1 0.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.5 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:0009008 S-methyltransferase activity(GO:0008172) DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection