Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for IKZF2

Z-value: 0.60

Motif logo

Transcription factors associated with IKZF2

Gene Symbol Gene ID Gene Info
ENSG00000030419.17 IKZF2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IKZF2hg38_v1_chr2_-_213150236_2131503340.144.7e-01Click!

Activity profile of IKZF2 motif

Sorted Z-values of IKZF2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IKZF2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr1_-_205422050 1.58 ENST00000367153.9
LEM domain containing 1
chr19_+_18386150 1.42 ENST00000252809.3
growth differentiation factor 15
chr20_+_59604527 1.35 ENST00000371015.6
phosphatase and actin regulator 3
chr2_+_209580024 1.25 ENST00000392194.5
microtubule associated protein 2
chr12_-_121802886 1.21 ENST00000545885.5
ENST00000542933.5
ENST00000428029.6
ENST00000541694.5
ENST00000536662.5
ENST00000535643.5
ENST00000541657.5
long intergenic non-protein coding RNA 1089
ras homolog family member F, filopodia associated
chr7_-_41700583 1.20 ENST00000442711.1
inhibin subunit beta A
chrX_+_136169833 1.14 ENST00000628032.2
four and a half LIM domains 1
chrX_+_136169624 1.13 ENST00000394153.6
four and a half LIM domains 1
chr6_+_106086316 1.08 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr8_-_124565699 1.05 ENST00000519168.5
MTSS I-BAR domain containing 1
chr2_+_209579399 1.01 ENST00000360351.8
microtubule associated protein 2
chr15_+_45430579 1.01 ENST00000558435.5
ENST00000344300.3
ENST00000396650.7
chromosome 15 open reading frame 48
chr2_+_209579598 1.01 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr7_-_23470469 1.01 ENST00000258729.8
insulin like growth factor 2 mRNA binding protein 3
chrX_+_136169664 1.00 ENST00000456445.5
four and a half LIM domains 1
chr9_+_34989641 0.99 ENST00000453597.8
ENST00000312316.9
ENST00000458263.6
ENST00000537321.5
ENST00000682809.1
ENST00000684748.1
DnaJ heat shock protein family (Hsp40) member B5
chrX_+_136148440 0.96 ENST00000627383.2
ENST00000630084.2
four and a half LIM domains 1
chr16_+_82626955 0.95 ENST00000268613.14
ENST00000567109.6
ENST00000565636.5
ENST00000431540.7
ENST00000428848.7
cadherin 13
chr15_+_73683938 0.93 ENST00000567189.5
CD276 molecule
chr6_-_131063233 0.91 ENST00000392427.7
ENST00000337057.8
ENST00000525271.5
ENST00000527411.5
erythrocyte membrane protein band 4.1 like 2
chr19_-_42765657 0.89 ENST00000406636.7
ENST00000404209.8
ENST00000306511.5
pregnancy specific beta-1-glycoprotein 8
chr6_-_131063272 0.88 ENST00000445890.6
ENST00000368128.6
ENST00000628542.2
erythrocyte membrane protein band 4.1 like 2
chr2_+_157257687 0.88 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr2_+_102337148 0.85 ENST00000311734.6
ENST00000409584.5
interleukin 1 receptor like 1
chr2_+_9961165 0.83 ENST00000405379.6
grainyhead like transcription factor 1
chrX_+_101550537 0.82 ENST00000372829.8
armadillo repeat containing X-linked 1
chrX_-_15664798 0.81 ENST00000380342.4
collectrin, amino acid transport regulator
chr6_+_106098933 0.81 ENST00000369089.3
PR/SET domain 1
chr10_-_99235783 0.78 ENST00000370546.5
ENST00000614306.1
heparanase 2 (inactive)
chr5_-_140633167 0.78 ENST00000302014.11
CD14 molecule
chr6_-_131063207 0.77 ENST00000530481.5
erythrocyte membrane protein band 4.1 like 2
chr12_+_26195647 0.77 ENST00000535504.1
sarcospan
chr2_+_17539964 0.77 ENST00000457525.5
visinin like 1
chr2_-_189179754 0.77 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chrX_+_136169891 0.77 ENST00000449474.5
four and a half LIM domains 1
chr17_-_17836997 0.74 ENST00000395757.6
sterol regulatory element binding transcription factor 1
chr7_-_122304738 0.73 ENST00000442488.7
FEZ family zinc finger 1
chr22_-_35824373 0.73 ENST00000473487.6
RNA binding fox-1 homolog 2
chr5_+_96875978 0.70 ENST00000510373.5
endoplasmic reticulum aminopeptidase 2
chr3_+_12351493 0.70 ENST00000683699.1
peroxisome proliferator activated receptor gamma
chr9_+_72628020 0.70 ENST00000646619.1
transmembrane channel like 1
chr3_+_130931893 0.69 ENST00000504612.5
ATPase secretory pathway Ca2+ transporting 1
chr2_-_24328113 0.68 ENST00000622089.4
intersectin 2
chr17_-_41118369 0.64 ENST00000391413.4
keratin associated protein 4-11
chr5_-_151686908 0.64 ENST00000231061.9
secreted protein acidic and cysteine rich
chr5_-_147831663 0.64 ENST00000296695.10
serine peptidase inhibitor Kazal type 1
chr4_-_48012934 0.63 ENST00000420489.7
ENST00000504722.6
cyclic nucleotide gated channel subunit alpha 1
chr17_-_676348 0.62 ENST00000681510.1
ENST00000679680.1
VPS53 subunit of GARP complex
chrX_-_41665766 0.60 ENST00000643043.2
ENST00000486402.1
ENST00000646087.2
calcium/calmodulin dependent serine protein kinase
chr7_+_93921720 0.56 ENST00000248564.6
G protein subunit gamma 11
chr12_-_27972725 0.55 ENST00000545234.6
parathyroid hormone like hormone
chr5_-_147831627 0.55 ENST00000510027.2
serine peptidase inhibitor Kazal type 1
chr3_+_12351470 0.54 ENST00000287820.10
peroxisome proliferator activated receptor gamma
chr1_-_121183911 0.54 ENST00000355228.8
family with sequence similarity 72 member B
chr6_+_47698574 0.53 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr1_-_169630115 0.53 ENST00000263686.11
ENST00000367788.6
selectin P
chr19_-_43205551 0.52 ENST00000599391.1
ENST00000244295.13
ENST00000596907.5
ENST00000405312.8
ENST00000451895.1
ENST00000433626.6
pregnancy specific beta-1-glycoprotein 4
chr2_+_209579429 0.52 ENST00000361559.8
microtubule associated protein 2
chrX_+_50067576 0.51 ENST00000376108.7
chloride voltage-gated channel 5
chr1_-_47190013 0.50 ENST00000294338.7
PDZK1 interacting protein 1
chrX_-_43882411 0.50 ENST00000378069.5
monoamine oxidase B
chr15_+_69414246 0.50 ENST00000260363.9
ENST00000395392.6
kinesin family member 23
chr15_+_69414304 0.49 ENST00000352331.8
ENST00000679126.1
ENST00000647715.1
ENST00000559279.6
kinesin family member 23
chr10_-_99235846 0.48 ENST00000370552.8
ENST00000370549.5
ENST00000628193.2
heparanase 2 (inactive)
chr1_+_24319511 0.47 ENST00000356046.6
grainyhead like transcription factor 3
chr17_-_41055211 0.47 ENST00000542910.1
ENST00000398477.1
keratin associated protein 2-2
chr2_-_85410336 0.47 ENST00000263867.9
ENST00000409921.5
capping actin protein, gelsolin like
chr1_+_24319342 0.47 ENST00000361548.9
grainyhead like transcription factor 3
chr7_-_122304499 0.47 ENST00000427185.2
FEZ family zinc finger 1
chr18_-_49813869 0.46 ENST00000586485.5
ENST00000587994.5
ENST00000586100.1
acetyl-CoA acyltransferase 2
chr19_-_42917837 0.45 ENST00000292125.6
ENST00000402603.8
ENST00000594375.1
ENST00000187910.7
pregnancy specific beta-1-glycoprotein 6
chr4_-_122456725 0.45 ENST00000226730.5
interleukin 2
chr11_-_86068743 0.44 ENST00000356360.9
phosphatidylinositol binding clathrin assembly protein
chr14_+_35122660 0.44 ENST00000603544.5
protein only RNase P catalytic subunit
chr15_-_59372863 0.44 ENST00000288235.9
myosin IE
chr6_-_42217845 0.44 ENST00000053468.4
mitochondrial ribosomal protein S10
chr17_-_17836973 0.43 ENST00000261646.11
ENST00000355815.8
sterol regulatory element binding transcription factor 1
chr6_+_27138588 0.43 ENST00000615353.1
H4 clustered histone 9
chr9_+_706841 0.42 ENST00000382293.7
KN motif and ankyrin repeat domains 1
chr7_+_129375643 0.42 ENST00000490911.5
adenosylhomocysteinase like 2
chr19_-_41353904 0.42 ENST00000221930.6
transforming growth factor beta 1
chr16_-_18876305 0.42 ENST00000563235.5
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr19_+_11089446 0.42 ENST00000557933.5
ENST00000455727.6
ENST00000535915.5
ENST00000545707.5
ENST00000558518.6
ENST00000558013.5
low density lipoprotein receptor
chrX_-_64205680 0.41 ENST00000374869.8
APC membrane recruitment protein 1
chr1_+_40161355 0.41 ENST00000372771.5
RLF zinc finger
chr19_-_49361475 0.41 ENST00000598810.5
TEA domain transcription factor 2
chr2_+_191678122 0.40 ENST00000425611.9
ENST00000410026.7
nucleic acid binding protein 1
chr19_-_43527189 0.40 ENST00000292147.7
ENST00000600651.5
ETHE1 persulfide dioxygenase
chr1_-_28058087 0.40 ENST00000373864.5
EYA transcriptional coactivator and phosphatase 3
chr20_+_45881218 0.40 ENST00000372523.1
zinc finger SWIM-type containing 1
chr2_-_133568393 0.40 ENST00000317721.10
ENST00000405974.7
ENST00000409261.6
ENST00000409213.5
NCK associated protein 5
chr9_-_91423819 0.39 ENST00000297689.4
nuclear factor, interleukin 3 regulated
chr2_-_55334529 0.39 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
coiled-coil domain containing 88A
chrX_-_101407893 0.38 ENST00000676156.1
ENST00000675592.1
ENST00000674634.2
ENST00000649178.1
ENST00000218516.4
galactosidase alpha
chr19_-_42937098 0.37 ENST00000623675.3
ENST00000446844.3
pregnancy specific beta-1-glycoprotein 7
chr19_-_42740384 0.37 ENST00000614582.1
ENST00000595140.5
ENST00000327495.10
pregnancy specific beta-1-glycoprotein 3
chr4_-_39032922 0.37 ENST00000344606.6
transmembrane protein 156
chr12_-_79935069 0.37 ENST00000450142.7
protein phosphatase 1 regulatory subunit 12A
chr4_+_157220691 0.37 ENST00000509417.5
ENST00000645636.1
ENST00000296526.12
ENST00000264426.14
glutamate ionotropic receptor AMPA type subunit 2
chr2_-_24360299 0.36 ENST00000361999.7
intersectin 2
chr4_-_152382522 0.36 ENST00000296555.11
F-box and WD repeat domain containing 7
chr15_-_55249029 0.36 ENST00000566877.5
RAB27A, member RAS oncogene family
chr13_-_37598750 0.35 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr2_-_213150236 0.35 ENST00000442445.1
ENST00000342002.6
IKAROS family zinc finger 2
chr1_-_155978427 0.35 ENST00000313667.8
Rho/Rac guanine nucleotide exchange factor 2
chr7_+_1086800 0.35 ENST00000413368.5
ENST00000397092.5
ENST00000297469.3
G protein-coupled estrogen receptor 1
chr11_-_55936400 0.34 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr4_-_70666492 0.34 ENST00000254801.9
ENST00000391614.7
joining chain of multimeric IgA and IgM
chr5_-_102499008 0.34 ENST00000389019.7
solute carrier organic anion transporter family member 6A1
chr5_-_102498913 0.34 ENST00000513675.1
ENST00000379807.7
ENST00000506729.6
solute carrier organic anion transporter family member 6A1
chr1_+_156893678 0.34 ENST00000292357.8
ENST00000338302.7
ENST00000455314.5
platelet endothelial aggregation receptor 1
chr12_+_26195543 0.34 ENST00000242729.7
sarcospan
chr12_-_11134644 0.33 ENST00000539585.1
taste 2 receptor member 30
chr22_+_39901075 0.33 ENST00000344138.9
GRB2 related adaptor protein 2
chr10_+_30434021 0.33 ENST00000542547.5
mitogen-activated protein kinase kinase kinase 8
chr6_+_15246054 0.33 ENST00000341776.7
jumonji and AT-rich interaction domain containing 2
chr2_-_118847638 0.33 ENST00000295206.7
engrailed homeobox 1
chr8_+_30387064 0.32 ENST00000523115.5
ENST00000519647.5
RNA binding protein, mRNA processing factor
chr12_+_26195313 0.32 ENST00000422622.3
sarcospan
chr8_+_39913881 0.32 ENST00000518237.6
indoleamine 2,3-dioxygenase 1
chr6_-_10412367 0.32 ENST00000379608.9
transcription factor AP-2 alpha
chr1_-_155978524 0.32 ENST00000361247.9
Rho/Rac guanine nucleotide exchange factor 2
chr11_-_1757452 0.32 ENST00000427721.3
novel protein
chr20_-_52191697 0.32 ENST00000361387.6
ZFP64 zinc finger protein
chr1_+_100719734 0.32 ENST00000370119.8
ENST00000294728.7
ENST00000347652.6
ENST00000370115.1
vascular cell adhesion molecule 1
chr4_+_157220654 0.31 ENST00000393815.6
glutamate ionotropic receptor AMPA type subunit 2
chr2_+_233032672 0.31 ENST00000233840.3
neuraminidase 2
chr6_+_116399395 0.31 ENST00000644499.1
novel protein
chr1_+_117420597 0.31 ENST00000449370.6
mannosidase alpha class 1A member 2
chr10_+_30434176 0.31 ENST00000263056.6
ENST00000375322.2
mitogen-activated protein kinase kinase kinase 8
chr3_+_179148341 0.30 ENST00000263967.4
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr14_-_56816693 0.30 ENST00000673035.1
orthodenticle homeobox 2
chr19_+_30372364 0.29 ENST00000355537.4
zinc finger protein 536
chr11_+_18396266 0.29 ENST00000540430.5
ENST00000379412.9
lactate dehydrogenase A
chr10_-_75109085 0.29 ENST00000607131.5
dual specificity phosphatase 13
chr10_-_11532275 0.29 ENST00000277575.5
USP6 N-terminal like
chr4_-_113979635 0.28 ENST00000315366.8
arylsulfatase family member J
chr16_-_58295019 0.28 ENST00000567164.6
ENST00000219301.8
ENST00000569727.1
serine protease 54
chr16_-_58294976 0.28 ENST00000543437.5
ENST00000569079.1
serine protease 54
chr15_+_66386902 0.28 ENST00000307102.10
mitogen-activated protein kinase kinase 1
chr2_+_26970628 0.28 ENST00000233121.7
ENST00000405074.7
microtubule associated protein RP/EB family member 3
chr10_-_101839818 0.28 ENST00000348850.9
potassium voltage-gated channel interacting protein 2
chr10_+_119818699 0.27 ENST00000650409.1
inositol polyphosphate-5-phosphatase F
chr22_-_28711931 0.27 ENST00000434810.5
ENST00000456369.5
checkpoint kinase 2
chr1_+_161749762 0.27 ENST00000367943.5
dual specificity phosphatase 12
chr8_+_96584920 0.27 ENST00000521590.5
syndecan 2
chr22_-_35840218 0.27 ENST00000414461.6
ENST00000416721.6
ENST00000449924.6
ENST00000262829.11
ENST00000397305.3
RNA binding fox-1 homolog 2
chr13_+_27620945 0.27 ENST00000621089.2
RNA polymerase I and III subunit D
chr1_+_158831323 0.26 ENST00000368141.5
myeloid cell nuclear differentiation antigen
chr4_+_133149307 0.26 ENST00000618019.1
protocadherin 10
chr15_+_81000913 0.26 ENST00000267984.4
talin rod domain containing 1
chr4_+_147732070 0.26 ENST00000336498.8
Rho GTPase activating protein 10
chr7_+_107583919 0.26 ENST00000491150.5
B cell receptor associated protein 29
chr17_+_7484357 0.25 ENST00000674977.2
RNA polymerase II subunit A
chr2_+_135531460 0.25 ENST00000683871.1
ENST00000409478.5
ENST00000264160.8
ENST00000438014.5
R3H domain containing 1
chr7_+_120988683 0.25 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr3_+_10026409 0.25 ENST00000287647.7
ENST00000676013.1
ENST00000675286.1
ENST00000419585.5
FA complementation group D2
chr12_+_59664677 0.25 ENST00000548610.5
solute carrier family 16 member 7
chr12_-_10986912 0.25 ENST00000506868.1
taste 2 receptor member 50
chr5_+_58491451 0.25 ENST00000513924.2
ENST00000515443.2
GRB2 binding adaptor protein, transmembrane
chr22_-_35840577 0.25 ENST00000405409.6
RNA binding fox-1 homolog 2
chr12_+_6494087 0.25 ENST00000382457.8
ENST00000315579.10
non-SMC condensin I complex subunit D2
chr5_-_152405277 0.24 ENST00000255262.4
neuromedin U receptor 2
chr2_+_188974364 0.24 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr16_-_20900319 0.24 ENST00000564349.5
ENST00000324344.9
ERI1 exoribonuclease family member 2
defective in cullin neddylation 1 domain containing 3
chr18_+_24460630 0.24 ENST00000256906.5
histamine receptor H4
chr11_+_22338333 0.24 ENST00000263160.4
solute carrier family 17 member 6
chr1_-_152325232 0.24 ENST00000368799.2
filaggrin
chr14_+_35122722 0.24 ENST00000605870.5
ENST00000557404.3
protein only RNase P catalytic subunit
chr10_-_75109172 0.24 ENST00000372700.7
ENST00000473072.2
ENST00000491677.6
ENST00000372702.7
dual specificity phosphatase 13
chr11_+_126283059 0.24 ENST00000392679.6
ENST00000392678.7
ENST00000392680.6
TIR domain containing adaptor protein
chr11_-_72674394 0.23 ENST00000418754.6
ENST00000334456.10
ENST00000542969.2
phosphodiesterase 2A
chr10_-_96271508 0.23 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr7_-_106284524 0.23 ENST00000681936.1
ENST00000680786.1
ENST00000681550.1
nicotinamide phosphoribosyltransferase
chr7_-_14841267 0.23 ENST00000406247.7
ENST00000399322.7
diacylglycerol kinase beta
chr12_-_55688891 0.23 ENST00000557555.2
integrin subunit alpha 7
chr13_-_46182136 0.23 ENST00000323076.7
lymphocyte cytosolic protein 1
chr11_-_19241598 0.23 ENST00000532666.1
ENST00000527884.5
ENST00000620009.4
E2F transcription factor 8
chr10_-_96271553 0.22 ENST00000224337.10
B cell linker
chr21_+_38256984 0.22 ENST00000398938.7
potassium inwardly rectifying channel subfamily J member 15
chr18_+_24460655 0.22 ENST00000426880.2
histamine receptor H4
chrX_+_28587411 0.22 ENST00000378993.6
interleukin 1 receptor accessory protein like 1
chr14_-_106211453 0.21 ENST00000390606.3
immunoglobulin heavy variable 3-20
chr17_+_7012417 0.21 ENST00000548577.5
ribonuclease K
chr12_+_106582996 0.21 ENST00000392842.6
regulatory factor X4
chr20_-_14337602 0.21 ENST00000378053.3
ENST00000341420.5
fibronectin leucine rich transmembrane protein 3
chr12_-_104050112 0.21 ENST00000547583.1
ENST00000546851.1
ENST00000360814.9
glycosyltransferase 8 domain containing 2
chr3_-_169769542 0.21 ENST00000330368.3
actin related protein T3
chr12_-_91179517 0.21 ENST00000551354.1
decorin
chr9_+_136807911 0.20 ENST00000371671.9
ENST00000311502.12
ENST00000371663.10
RAB, member RAS oncogene family like 6
chr19_+_18340581 0.20 ENST00000604499.6
ENST00000269919.11
ENST00000595066.5
ENST00000252813.5
pyroglutamyl-peptidase I
chr6_+_142147162 0.20 ENST00000452973.6
ENST00000620996.4
ENST00000367621.1
ENST00000367630.9
vesicle trafficking 1
chr2_+_196639686 0.20 ENST00000389175.9
coiled-coil domain containing 150
chr17_-_40782544 0.20 ENST00000301656.4
keratin 27
chr19_+_49930219 0.20 ENST00000596658.1
activating transcription factor 5
chr2_+_48568981 0.19 ENST00000394754.5
STON1-GTF2A1L readthrough
chr17_-_38748184 0.19 ENST00000618941.4
ENST00000620225.5
ENST00000618506.1
ENST00000616129.4
polycomb group ring finger 2
chr1_-_150269051 0.19 ENST00000414276.6
ENST00000360244.8
aph-1 homolog A, gamma-secretase subunit
chr4_+_176065980 0.19 ENST00000280190.8
WD repeat domain 17
chr6_-_11778781 0.19 ENST00000414691.8
ENST00000229583.9
androgen dependent TFPI regulating protein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.4 1.2 GO:0060279 positive regulation of ovulation(GO:0060279)
0.3 0.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 1.0 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 0.2 GO:0071221 response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.2 1.0 GO:0030035 microspike assembly(GO:0030035)
0.2 1.2 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.2 1.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2 0.8 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 1.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.7 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 2.6 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 1.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.3 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 0.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.4 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.4 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.4 GO:0052251 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1 0.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.4 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.3 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.9 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 0.3 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.3 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.1 0.6 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.1 0.3 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 1.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:1990523 bone regeneration(GO:1990523)
0.1 0.2 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023) activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.3 GO:0036269 swimming behavior(GO:0036269)
0.1 0.3 GO:0003409 optic vesicle morphogenesis(GO:0003404) optic cup structural organization(GO:0003409)
0.1 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.4 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
0.1 0.5 GO:0014063 response to aluminum ion(GO:0010044) negative regulation of serotonin secretion(GO:0014063)
0.1 1.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.7 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.8 GO:0002934 desmosome organization(GO:0002934)
0.1 0.3 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.3 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.5 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.6 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.9 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.4 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.3 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.0 0.7 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.5 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.2 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 4.5 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.4 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 1.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:1904170 positive regulation of interleukin-1 alpha secretion(GO:0050717) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.4 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.3 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.0 0.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.0 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.2 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.4 GO:0015074 DNA integration(GO:0015074)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 3.8 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.3 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086) positive regulation of transcription by glucose(GO:0046016)
0.0 0.4 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.1 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.0 GO:0060100 positive regulation of phagocytosis, engulfment(GO:0060100) positive regulation of membrane invagination(GO:1905155)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.6 GO:0002076 osteoblast development(GO:0002076)
0.0 0.2 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.8 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.3 GO:0097369 sodium ion import(GO:0097369)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.1 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.1 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.0 0.1 GO:0042262 DNA protection(GO:0042262)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.2 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.3 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.3 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 1.0 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 1.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.7 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 1.0 GO:0097149 centralspindlin complex(GO:0097149)
0.1 2.6 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 0.3 GO:0071754 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.1 0.3 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 0.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.8 GO:1990745 EARP complex(GO:1990745)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.2 GO:0043293 apoptosome(GO:0043293)
0.1 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.7 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.0 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0030305 heparanase activity(GO:0030305)
0.3 0.9 GO:0055100 adiponectin binding(GO:0055100)
0.3 0.8 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 1.2 GO:0032810 sterol response element binding(GO:0032810)
0.2 2.6 GO:0042731 PH domain binding(GO:0042731)
0.2 1.0 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 1.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 4.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.8 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 1.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.3 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.3 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0019862 IgA binding(GO:0019862)
0.1 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.6 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.7 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.5 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.2 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250) ER retention sequence binding(GO:0046923)
0.0 0.3 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.0 0.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 1.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 3.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.0 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 4.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 1.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.0 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 3.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism