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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for IRF3

Z-value: 1.19

Motif logo

Transcription factors associated with IRF3

Gene Symbol Gene ID Gene Info
ENSG00000126456.16 IRF3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF3hg38_v1_chr19_-_49665603_496656170.222.3e-01Click!

Activity profile of IRF3 motif

Sorted Z-values of IRF3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_143132069 6.39 ENST00000291009.4
prolactin induced protein
chr8_+_39913881 4.53 ENST00000518237.6
indoleamine 2,3-dioxygenase 1
chr1_+_78649818 4.43 ENST00000370747.9
ENST00000438486.1
interferon induced protein 44
chr7_-_122886706 3.93 ENST00000313070.11
ENST00000334010.11
ENST00000615869.4
calcium dependent secretion activator 2
chr12_+_6452024 3.79 ENST00000266556.8
ENST00000544021.5
TAP binding protein like
chr20_-_25058115 3.72 ENST00000323482.9
acyl-CoA synthetase short chain family member 1
chr20_-_25058168 3.71 ENST00000432802.6
acyl-CoA synthetase short chain family member 1
chr19_-_17405554 3.36 ENST00000252593.7
bone marrow stromal cell antigen 2
chr6_+_32854179 3.29 ENST00000374859.3
proteasome 20S subunit beta 9
chr10_+_89327989 3.18 ENST00000679923.1
ENST00000680085.1
ENST00000371818.9
ENST00000680779.1
interferon induced protein with tetratricopeptide repeats 3
chr10_+_89327977 3.09 ENST00000681277.1
interferon induced protein with tetratricopeptide repeats 3
chr4_-_168318770 2.99 ENST00000680771.1
ENST00000514995.2
DExD/H-box helicase 60
chr4_-_168318743 2.93 ENST00000393743.8
DExD/H-box helicase 60
chr10_+_89332484 2.81 ENST00000371811.4
ENST00000680037.1
ENST00000679583.1
ENST00000679897.1
interferon induced protein with tetratricopeptide repeats 3
chr1_+_1013485 2.79 ENST00000649529.1
ISG15 ubiquitin like modifier
chr7_-_122886439 2.77 ENST00000412584.6
ENST00000449022.7
calcium dependent secretion activator 2
chr21_+_41420515 2.76 ENST00000398600.6
ENST00000679626.1
MX dynamin like GTPase 1
chrX_+_57286680 2.48 ENST00000374900.5
fatty acid amide hydrolase 2
chr9_-_32526185 2.30 ENST00000379883.3
ENST00000379868.6
ENST00000679859.1
DExD/H-box helicase 58
chr2_+_69013170 2.23 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr17_+_6756035 2.19 ENST00000361842.8
ENST00000574907.5
XIAP associated factor 1
chr2_-_162318475 2.17 ENST00000648433.1
interferon induced with helicase C domain 1
chr2_-_6865901 2.10 ENST00000256722.10
cytidine/uridine monophosphate kinase 2
chr4_-_155953851 1.93 ENST00000679136.1
ENST00000433477.4
ENST00000679996.1
ENST00000680741.1
ENST00000680553.1
ENST00000679942.1
cathepsin O
chr7_+_101085464 1.78 ENST00000306085.11
ENST00000412507.1
tripartite motif containing 56
chr17_-_42112674 1.78 ENST00000251642.8
ENST00000591220.5
DExH-box helicase 58
chr12_+_12071396 1.71 ENST00000396367.5
ENST00000266434.8
BCL2 like 14
chr12_+_12070932 1.71 ENST00000308721.9
BCL2 like 14
chr11_-_57567617 1.71 ENST00000287156.9
ubiquitin conjugating enzyme E2 L6
chr16_+_58249910 1.68 ENST00000219299.8
ENST00000443128.6
ENST00000616795.1
coiled-coil domain containing 113
chr2_-_219387881 1.62 ENST00000322176.11
ENST00000273075.9
aspartyl aminopeptidase
chr10_+_89301932 1.60 ENST00000371826.4
ENST00000679755.1
interferon induced protein with tetratricopeptide repeats 2
chr11_+_63536801 1.59 ENST00000255688.8
ENST00000439013.6
phospholipase A and acyltransferase 4
chr17_+_6755834 1.53 ENST00000346752.8
XIAP associated factor 1
chr2_-_162318129 1.52 ENST00000679938.1
interferon induced with helicase C domain 1
chr6_+_26440472 1.47 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
butyrophilin subfamily 3 member A3
chr6_+_26365215 1.44 ENST00000527422.5
ENST00000356386.6
ENST00000396948.5
butyrophilin subfamily 3 member A2
chr3_-_195811916 1.43 ENST00000463781.8
mucin 4, cell surface associated
chr20_-_49278034 1.39 ENST00000371744.5
ENST00000396105.6
ENST00000371752.5
zinc finger NFX1-type containing 1
chr19_+_49928702 1.38 ENST00000595125.5
activating transcription factor 5
chr6_-_36387566 1.37 ENST00000339796.9
ENST00000627426.2
ETS variant transcription factor 7
chr2_+_162318884 1.36 ENST00000446271.5
ENST00000429691.6
grancalcin
chr19_+_18173804 1.36 ENST00000407280.4
IFI30 lysosomal thiol reductase
chr2_-_156342348 1.34 ENST00000409572.5
nuclear receptor subfamily 4 group A member 2
chr12_+_112978424 1.30 ENST00000680685.1
ENST00000620097.2
2'-5'-oligoadenylate synthetase 2
chr6_+_26365176 1.29 ENST00000377708.7
butyrophilin subfamily 3 member A2
chr19_-_47232649 1.29 ENST00000449228.5
ENST00000300880.11
ENST00000341983.8
BCL2 binding component 3
chr12_+_112978460 1.26 ENST00000449768.2
2'-5'-oligoadenylate synthetase 2
chr1_+_110034607 1.24 ENST00000369795.8
striatin interacting protein 1
chr6_+_26402237 1.23 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
butyrophilin subfamily 3 member A1
chr17_+_42289213 1.22 ENST00000677301.1
signal transducer and activator of transcription 5A
chr21_-_41926680 1.22 ENST00000329623.11
C2 calcium dependent domain containing 2
chrX_+_77899440 1.21 ENST00000373335.4
ENST00000475465.1
ENST00000650309.2
ENST00000647835.1
cytochrome c oxidase subunit 7B
chr7_-_93148345 1.15 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chr6_+_26365159 1.11 ENST00000532865.5
ENST00000396934.7
ENST00000508906.6
ENST00000530653.5
ENST00000527417.5
butyrophilin subfamily 3 member A2
chr2_+_126656128 1.07 ENST00000259254.9
ENST00000409836.3
ENST00000356887.12
glycophorin C (Gerbich blood group)
chr10_-_47384261 1.06 ENST00000591025.1
ENST00000585316.3
zinc finger protein 488
chr9_-_87974487 1.05 ENST00000375871.8
ENST00000605159.5
ENST00000325303.9
ENST00000336654.9
cyclin dependent kinase 20
chr2_+_69013282 1.05 ENST00000409829.7
ANTXR cell adhesion molecule 1
chr14_+_73058521 1.03 ENST00000527432.5
ENST00000531500.5
ENST00000261973.12
ENST00000525321.5
ENST00000526754.5
RNA binding motif protein 25
chr9_-_87974667 1.02 ENST00000375883.7
cyclin dependent kinase 20
chr6_-_121334450 1.01 ENST00000398212.7
TBC1 domain family member 32
chr1_+_210329294 0.98 ENST00000367010.5
hedgehog acyltransferase
chr2_-_230219902 0.98 ENST00000409815.6
SP110 nuclear body protein
chr14_+_73058591 0.97 ENST00000525161.5
RNA binding motif protein 25
chr1_+_210328894 0.95 ENST00000261458.8
ENST00000537898.5
ENST00000545154.5
hedgehog acyltransferase
chr4_+_155666718 0.93 ENST00000621234.4
ENST00000511108.5
guanylate cyclase 1 soluble subunit alpha 1
chr6_+_26402289 0.91 ENST00000414912.2
butyrophilin subfamily 3 member A1
chr19_+_49929196 0.89 ENST00000423777.7
ENST00000600336.1
ENST00000597227.5
activating transcription factor 5
chr3_+_122680802 0.88 ENST00000474629.7
poly(ADP-ribose) polymerase family member 14
chr12_+_133037276 0.87 ENST00000392319.6
ENST00000543758.5
zinc finger protein 84
chr2_+_204545446 0.87 ENST00000406610.7
par-3 family cell polarity regulator beta
chr7_-_140062841 0.86 ENST00000263549.8
poly(ADP-ribose) polymerase family member 12
chr9_-_137188540 0.85 ENST00000323927.3
anaphase promoting complex subunit 2
chr12_+_133037476 0.84 ENST00000540031.5
ENST00000539354.6
ENST00000536123.5
zinc finger protein 84
chr4_+_155667198 0.83 ENST00000296518.11
guanylate cyclase 1 soluble subunit alpha 1
chr14_-_70416994 0.82 ENST00000621525.4
ENST00000256366.6
SYNJ2BP-COX16 readthrough
synaptojanin 2 binding protein
chr11_-_124320197 0.78 ENST00000624618.2
olfactory receptor family 8 subfamily D member 2
chr4_+_155667096 0.78 ENST00000393832.7
guanylate cyclase 1 soluble subunit alpha 1
chr9_-_92325577 0.78 ENST00000358855.8
ENST00000421075.6
ENST00000536624.5
nucleolar protein 8
chr1_-_89198868 0.77 ENST00000355754.7
guanylate binding protein 4
chr4_+_155666963 0.77 ENST00000455639.6
guanylate cyclase 1 soluble subunit alpha 1
chr20_-_20052389 0.77 ENST00000536226.2
crooked neck pre-mRNA splicing factor 1
chr2_-_230219944 0.77 ENST00000455674.2
ENST00000392048.7
ENST00000258381.11
ENST00000358662.9
ENST00000258382.10
SP110 nuclear body protein
chr17_-_35880350 0.76 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
C-C motif chemokine ligand 5
chr5_-_96807899 0.74 ENST00000503921.5
ENST00000508227.5
ENST00000507154.1
ENST00000443439.7
endoplasmic reticulum aminopeptidase 1
chr12_+_133037533 0.73 ENST00000327668.11
zinc finger protein 84
chr20_-_21514046 0.71 ENST00000377142.5
NK2 homeobox 2
chr1_+_151156627 0.71 ENST00000368910.4
TNF alpha induced protein 8 like 2
chr3_+_187368367 0.70 ENST00000259030.3
receptor transporter protein 4
chr9_-_92325322 0.70 ENST00000542613.5
ENST00000542053.5
ENST00000442668.7
ENST00000545558.5
ENST00000432670.6
ENST00000433029.6
ENST00000411621.6
nucleolar protein 8
chr12_-_214146 0.70 ENST00000684302.1
solute carrier family 6 member 12
chr3_-_126084263 0.68 ENST00000346785.9
ENST00000315891.10
solute carrier family 41 member 3
chr6_+_31927486 0.67 ENST00000442278.6
complement C2
chr2_-_219387784 0.64 ENST00000520694.6
aspartyl aminopeptidase
chr11_-_4393650 0.64 ENST00000254436.8
tripartite motif containing 21
chr10_-_118595637 0.62 ENST00000239032.4
prolactin releasing hormone receptor
chr2_+_69013337 0.62 ENST00000463335.2
ANTXR cell adhesion molecule 1
chr1_+_111755892 0.60 ENST00000369702.5
ENST00000680627.1
ENST00000680518.1
DEAD-box helicase 20
chr4_+_155666827 0.60 ENST00000511507.5
ENST00000506455.6
guanylate cyclase 1 soluble subunit alpha 1
chr9_-_94640130 0.58 ENST00000414122.1
fructose-bisphosphatase 1
chr19_+_17405685 0.57 ENST00000646744.1
ENST00000635536.2
ENST00000635060.2
ENST00000634291.2
ENST00000645298.1
ENST00000528911.5
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr20_-_63216102 0.57 ENST00000370339.8
ENST00000370334.4
YTH N6-methyladenosine RNA binding protein 1
chr14_+_24136152 0.56 ENST00000559123.5
ENST00000206451.11
ENST00000382708.7
ENST00000561435.5
proteasome activator subunit 1
chr1_-_154608140 0.55 ENST00000529168.2
ENST00000368474.9
ENST00000680305.1
ENST00000648231.2
adenosine deaminase RNA specific
chr22_-_36703723 0.54 ENST00000300105.7
calcium voltage-gated channel auxiliary subunit gamma 2
chr1_-_159076742 0.54 ENST00000368130.9
absent in melanoma 2
chr16_+_75647757 0.52 ENST00000300086.5
ENST00000653858.1
TERF2 interacting protein
chr14_-_24146596 0.49 ENST00000560410.5
ENST00000216802.10
ENST00000615264.4
ENST00000630027.1
proteasome activator subunit 2
chr12_-_213656 0.49 ENST00000359674.8
solute carrier family 6 member 12
chr6_-_30213379 0.49 ENST00000418026.1
ENST00000454678.7
ENST00000416596.5
ENST00000453195.5
tripartite motif containing 26
chr10_-_48493641 0.48 ENST00000417247.6
Rho GTPase activating protein 22
chr3_+_51943244 0.48 ENST00000498510.2
poly(ADP-ribose) polymerase family member 3
chr12_-_8066331 0.47 ENST00000546241.1
ENST00000307637.5
complement C3a receptor 1
chr7_-_106285898 0.47 ENST00000424768.2
ENST00000681255.1
nicotinamide phosphoribosyltransferase
chr7_-_139109702 0.47 ENST00000471652.1
ENST00000242351.10
zinc finger CCCH-type containing, antiviral 1
chr19_+_10086305 0.47 ENST00000253110.16
ENST00000591813.5
shiftless antiviral inhibitor of ribosomal frameshifting
chr3_-_126083922 0.46 ENST00000514891.5
ENST00000512470.5
ENST00000504035.5
ENST00000513723.5
ENST00000510651.5
ENST00000514333.5
ENST00000360370.9
ENST00000514677.5
solute carrier family 41 member 3
chr11_+_32091065 0.45 ENST00000054950.4
reticulocalbin 1
chr6_-_36387736 0.43 ENST00000373737.8
ENST00000373738.4
ENST00000538992.3
ENST00000615781.4
ENST00000620358.4
ETS variant transcription factor 7
chr22_+_18150162 0.43 ENST00000215794.8
ubiquitin specific peptidase 18
chr6_-_36387654 0.42 ENST00000340181.9
ETS variant transcription factor 7
chr6_-_32853618 0.42 ENST00000354258.5
transporter 1, ATP binding cassette subfamily B member
chr6_+_28225257 0.42 ENST00000531981.5
ENST00000425468.6
ENST00000252207.10
ENST00000531979.5
ENST00000527436.5
zinc finger and SCAN domain containing 9
chr16_-_29863117 0.41 ENST00000566113.5
ENST00000569956.5
ENST00000570016.5
ENST00000219789.11
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr7_+_135148041 0.40 ENST00000275767.3
transmembrane protein 140
chr3_+_155870623 0.39 ENST00000295920.7
ENST00000496455.7
guanine monophosphate synthase
chr10_+_91220603 0.39 ENST00000336126.6
polycomb group ring finger 5
chr6_-_32853813 0.36 ENST00000643049.2
transporter 1, ATP binding cassette subfamily B member
chr10_-_27243019 0.36 ENST00000679293.1
acyl-CoA binding domain containing 5
chr14_-_91510450 0.35 ENST00000555462.5
protein phosphatase 4 regulatory subunit 3A
chr2_-_231125032 0.35 ENST00000258400.4
5-hydroxytryptamine receptor 2B
chr15_-_44711306 0.34 ENST00000682850.1
PAT1 homolog 2
chr14_+_65412949 0.34 ENST00000674118.1
ENST00000553924.5
ENST00000358307.6
ENST00000557338.5
ENST00000554610.1
fucosyltransferase 8
chr2_-_162318613 0.32 ENST00000649979.2
ENST00000421365.2
interferon induced with helicase C domain 1
chr6_+_42050513 0.32 ENST00000372978.7
ENST00000494547.5
ENST00000456846.6
ENST00000372982.8
ENST00000472818.5
ENST00000372977.8
TATA-box binding protein associated factor 8
chr19_+_17405734 0.32 ENST00000635572.1
ENST00000634675.1
ENST00000634813.1
ENST00000647283.1
ENST00000635435.2
ENST00000634731.2
ENST00000635339.1
ENST00000528604.5
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr9_-_14322320 0.30 ENST00000606230.2
nuclear factor I B
chr11_+_118359572 0.29 ENST00000252108.8
ENST00000431736.6
ubiquitination factor E4A
chr6_+_42050876 0.29 ENST00000465926.5
ENST00000482432.1
TATA-box binding protein associated factor 8
chr14_-_24146314 0.29 ENST00000559056.5
proteasome activator subunit 2
chr16_-_29862890 0.28 ENST00000563415.1
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr3_-_27722316 0.28 ENST00000449599.4
eomesodermin
chr20_+_45881218 0.26 ENST00000372523.1
zinc finger SWIM-type containing 1
chr15_+_75201873 0.26 ENST00000394987.5
chromosome 15 open reading frame 39
chr4_+_143513661 0.25 ENST00000283131.4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr8_+_22589240 0.24 ENST00000450780.6
ENST00000430850.6
ENST00000447849.2
ENST00000614502.4
ENST00000443561.3
novel protein
PDZ and LIM domain 2
chr10_+_35127295 0.24 ENST00000489321.5
ENST00000427847.6
ENST00000374728.7
ENST00000345491.7
ENST00000487132.5
cAMP responsive element modulator
chr10_-_22003678 0.23 ENST00000376980.8
DnaJ heat shock protein family (Hsp40) member C1
chrX_+_120250752 0.23 ENST00000326624.2
ENST00000557385.2
zinc finger and BTB domain containing 33
chr14_+_65412717 0.23 ENST00000673929.1
fucosyltransferase 8
chr22_-_36239517 0.23 ENST00000358502.10
ENST00000451256.6
apolipoprotein L2
chr4_-_86934700 0.22 ENST00000473559.5
novel protein
chr22_+_36253071 0.21 ENST00000422706.5
ENST00000426053.5
ENST00000319136.8
apolipoprotein L1
chr12_+_4649097 0.21 ENST00000648836.1
ENST00000266544.10
novel protein
NADH:ubiquinone oxidoreductase subunit A9
chr20_+_408147 0.21 ENST00000441733.5
ENST00000353660.7
RANBP2-type and C3HC4-type zinc finger containing 1
chr4_-_73982019 0.20 ENST00000296029.4
platelet factor 4
chr19_+_49474208 0.20 ENST00000597551.6
ENST00000596435.5
ENST00000204637.6
ENST00000600429.5
fms related receptor tyrosine kinase 3 ligand
chr1_+_75724431 0.19 ENST00000541113.6
ENST00000680805.1
acyl-CoA dehydrogenase medium chain
chr1_+_236394268 0.19 ENST00000334232.9
EDAR associated death domain
chr2_+_6865557 0.19 ENST00000680607.1
ENST00000680320.1
ENST00000442639.6
radical S-adenosyl methionine domain containing 2
chr7_-_106284524 0.18 ENST00000681936.1
ENST00000680786.1
ENST00000681550.1
nicotinamide phosphoribosyltransferase
chr10_+_113679839 0.18 ENST00000369318.8
ENST00000369315.5
caspase 7
chr22_+_36253124 0.17 ENST00000438034.5
ENST00000427990.5
ENST00000397278.8
ENST00000397279.8
ENST00000433768.5
apolipoprotein L1
chr15_+_44711487 0.17 ENST00000544417.5
ENST00000559916.1
ENST00000648006.3
beta-2-microglobulin
chr18_-_6414885 0.16 ENST00000317931.12
ENST00000400104.7
L3MBTL histone methyl-lysine binding protein 4
chr2_+_189857393 0.16 ENST00000452382.1
PMS1 homolog 1, mismatch repair system component
chr3_-_127591036 0.14 ENST00000489960.5
ENST00000490290.5
transmembrane protein adipocyte associated 1
chr22_+_35648438 0.13 ENST00000409652.5
apolipoprotein L6
chr4_+_99574812 0.12 ENST00000422897.6
ENST00000265517.10
microsomal triglyceride transfer protein
chr10_+_113679523 0.11 ENST00000345633.8
ENST00000614447.4
ENST00000369321.6
caspase 7
chr9_-_98192614 0.10 ENST00000375077.5
coronin 2A
chr3_-_27722699 0.10 ENST00000461503.2
eomesodermin
chr1_-_7940825 0.10 ENST00000377507.8
TNF receptor superfamily member 9
chr9_+_137188646 0.09 ENST00000322310.10
SS nuclear autoantigen 1
chr22_+_39077264 0.09 ENST00000407997.4
apolipoprotein B mRNA editing enzyme catalytic subunit 3G
chr8_+_108443601 0.08 ENST00000524143.5
ENST00000220853.8
ER membrane protein complex subunit 2
chr1_-_182589239 0.08 ENST00000367559.7
ENST00000539397.1
ribonuclease L
chr9_+_137188697 0.07 ENST00000464553.2
SS nuclear autoantigen 1
chr2_+_99154955 0.07 ENST00000393471.2
ENST00000393473.6
ENST00000651691.1
ENST00000449211.1
ENST00000434566.5
ENST00000410042.1
lipoyltransferase 1
novel LIPT1-MRPL30 readthrough
chr4_+_129096144 0.07 ENST00000425929.6
ENST00000508622.1
chromosome 4 open reading frame 33
chr2_+_112095189 0.07 ENST00000649734.1
transmembrane protein 87B
chr1_+_75724597 0.06 ENST00000681790.1
acyl-CoA dehydrogenase medium chain
chr19_+_49474561 0.04 ENST00000594009.5
ENST00000595510.1
ENST00000595815.1
fms related receptor tyrosine kinase 3 ligand
novel transcript
chr6_+_31572279 0.04 ENST00000418386.3
lymphotoxin alpha
chr5_-_95822711 0.04 ENST00000512469.2
ENST00000379979.8
ENST00000505427.1
ENST00000508780.5
ENST00000237858.11
glutaredoxin
chr1_+_75724672 0.03 ENST00000370834.9
ENST00000370841.9
ENST00000679687.1
ENST00000420607.6
acyl-CoA dehydrogenase medium chain
chr2_+_218260991 0.02 ENST00000522678.5
ENST00000519574.2
ENST00000521462.1
G protein-coupled bile acid receptor 1
chr11_-_67650682 0.02 ENST00000255082.8
aminoacylase 3
chr15_+_64136330 0.02 ENST00000560861.1
sorting nexin 1
chr6_+_31571957 0.01 ENST00000454783.5
lymphotoxin alpha
chr3_+_63912588 0.01 ENST00000522345.2
ataxin 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.4 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
1.5 7.7 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.3 6.3 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
1.1 4.5 GO:0036269 swimming behavior(GO:0036269)
1.1 3.4 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.8 3.9 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.8 2.3 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.7 10.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.7 2.1 GO:0006233 dUDP biosynthetic process(GO:0006227) dTDP biosynthetic process(GO:0006233) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dTDP metabolic process(GO:0046072) dUDP metabolic process(GO:0046077)
0.6 6.7 GO:1990504 dense core granule exocytosis(GO:1990504)
0.4 4.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.4 1.3 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 7.2 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.2 0.7 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 6.0 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 0.6 GO:0036071 N-glycan fucosylation(GO:0036071)
0.2 1.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 0.2 GO:0034761 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.2 2.0 GO:0018377 protein myristoylation(GO:0018377)
0.2 0.6 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.6 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 2.8 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.1 0.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.5 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.4 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 2.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.5 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.1 0.3 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.1 1.5 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 0.5 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.3 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 4.3 GO:0035456 response to interferon-beta(GO:0035456)
0.1 0.3 GO:0051793 medium-chain fatty acid catabolic process(GO:0051793)
0.1 1.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.4 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.3 GO:0019075 virus maturation(GO:0019075)
0.1 1.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 1.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 6.0 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.2 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 1.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.4 GO:0030242 pexophagy(GO:0030242)
0.0 2.1 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 1.1 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.8 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 1.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.7 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 2.5 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 1.2 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.7 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.0 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 1.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.4 3.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 1.3 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.8 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.1 0.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 3.9 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.2 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 1.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.5 GO:0070187 telosome(GO:0070187)
0.0 3.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 3.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 2.7 GO:0005811 lipid particle(GO:0005811)
0.0 5.9 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 2.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 6.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 2.6 GO:0072562 blood microparticle(GO:0072562)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 24.4 GO:0005739 mitochondrion(GO:0005739)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
1.5 4.5 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.7 2.1 GO:0004798 thymidylate kinase activity(GO:0004798)
0.4 2.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.4 6.4 GO:0019864 IgG binding(GO:0019864)
0.2 1.7 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 1.4 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.2 2.8 GO:0031386 protein tag(GO:0031386)
0.2 0.6 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.2 1.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 0.8 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298) CCR1 chemokine receptor binding(GO:0031726)
0.1 1.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.6 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 3.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.7 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.7 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 3.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.8 GO:0046979 TAP2 binding(GO:0046979)
0.1 12.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.3 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.1 0.7 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 1.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 1.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.5 GO:0004875 complement receptor activity(GO:0004875)
0.0 1.9 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 1.2 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 3.9 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.8 GO:0005549 odorant binding(GO:0005549)
0.0 0.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 1.4 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 1.9 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0008035 high-density lipoprotein particle binding(GO:0008035)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.2 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 5.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.4 4.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 6.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 18.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 4.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 3.5 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.8 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.1 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis