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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for IRF9

Z-value: 1.04

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Transcription factors associated with IRF9

Gene Symbol Gene ID Gene Info
IRF9
ENSG00000213928.9 IRF9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF9hg38_v1_chr14_+_24161257_24161322-0.038.6e-01Click!

Activity profile of IRF9 motif

Sorted Z-values of IRF9 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF9

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_6865901 6.38 ENST00000256722.10
CMPK2
cytidine/uridine monophosphate kinase 2
chr21_+_41361999 5.56 ENST00000436410.5
ENST00000435611.6
ENST00000330714.8
MX2
MX dynamin like GTPase 2
chr21_+_41426590 4.23 ENST00000679543.1
ENST00000680364.1
MX1
MX dynamin like GTPase 1
chr17_+_6756035 3.92 ENST00000361842.8
ENST00000574907.5
XAF1
XIAP associated factor 1
chr1_-_206946448 3.57 ENST00000356495.5
PIGR
polymeric immunoglobulin receptor
chr1_+_78649818 3.53 ENST00000370747.9
ENST00000438486.1
IFI44
interferon induced protein 44
chr8_+_39913881 3.11 ENST00000518237.6
IDO1
indoleamine 2,3-dioxygenase 1
chr17_+_6755834 2.95 ENST00000346752.8
XAF1
XIAP associated factor 1
chr9_+_72149351 2.85 ENST00000238018.8
GDA
guanine deaminase
chr4_-_168318770 2.74 ENST00000680771.1
ENST00000514995.2
DDX60
DExD/H-box helicase 60
chr4_-_168318743 2.70 ENST00000393743.8
DDX60
DExD/H-box helicase 60
chr9_-_32526185 2.56 ENST00000379883.3
ENST00000379868.6
ENST00000679859.1
DDX58
DExD/H-box helicase 58
chr1_-_150765785 2.55 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
CTSS
cathepsin S
chr21_+_41426197 2.55 ENST00000680942.1
ENST00000288383.11
ENST00000679386.1
MX1
MX dynamin like GTPase 1
chr2_+_6865557 2.52 ENST00000680607.1
ENST00000680320.1
ENST00000442639.6
RSAD2
radical S-adenosyl methionine domain containing 2
chr21_+_41426031 2.45 ENST00000455164.6
ENST00000681849.1
ENST00000679705.1
ENST00000424365.6
MX1
MX dynamin like GTPase 1
chr19_-_17405554 2.38 ENST00000252593.7
BST2
bone marrow stromal cell antigen 2
chr1_+_1013485 2.34 ENST00000649529.1
ISG15
ISG15 ubiquitin like modifier
chr21_+_41426168 2.33 ENST00000681266.1
ENST00000417963.6
MX1
MX dynamin like GTPase 1
chr1_-_150765735 2.24 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
CTSS
cathepsin S
chr21_+_41426289 2.17 ENST00000679408.1
ENST00000681039.1
ENST00000681671.1
MX1
MX dynamin like GTPase 1
chr21_+_41426232 2.16 ENST00000398598.8
ENST00000681896.1
ENST00000680629.1
ENST00000680760.1
ENST00000680176.1
ENST00000680776.1
ENST00000681607.1
ENST00000680536.1
MX1
MX dynamin like GTPase 1
chr12_-_121039204 2.10 ENST00000620239.5
OASL
2'-5'-oligoadenylate synthetase like
chr12_-_121039156 2.00 ENST00000339275.10
OASL
2'-5'-oligoadenylate synthetase like
chr6_-_46921926 1.99 ENST00000283296.12
ADGRF5
adhesion G protein-coupled receptor F5
chr12_-_121039236 1.98 ENST00000257570.9
OASL
2'-5'-oligoadenylate synthetase like
chr6_-_24935942 1.94 ENST00000645100.1
ENST00000643898.2
ENST00000613507.4
RIPOR2
RHO family interacting cell polarization regulator 2
chr11_-_86672114 1.61 ENST00000393324.7
ME3
malic enzyme 3
chr11_-_86672630 1.50 ENST00000543262.5
ME3
malic enzyme 3
chr11_-_86672419 1.44 ENST00000524826.7
ENST00000532471.1
ME3
malic enzyme 3
chr2_+_6877768 1.44 ENST00000382040.4
RSAD2
radical S-adenosyl methionine domain containing 2
chr2_-_55693817 1.37 ENST00000625249.1
ENST00000447944.7
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr7_+_101085464 1.23 ENST00000306085.11
ENST00000412507.1
TRIM56
tripartite motif containing 56
chr2_-_219387881 1.22 ENST00000322176.11
ENST00000273075.9
DNPEP
aspartyl aminopeptidase
chr1_+_241532121 1.15 ENST00000366558.7
KMO
kynurenine 3-monooxygenase
chr9_+_72149424 1.13 ENST00000358399.8
ENST00000376986.5
GDA
guanine deaminase
chr10_+_89332484 1.08 ENST00000371811.4
ENST00000680037.1
ENST00000679583.1
ENST00000679897.1
IFIT3
interferon induced protein with tetratricopeptide repeats 3
chr11_-_57567617 0.98 ENST00000287156.9
UBE2L6
ubiquitin conjugating enzyme E2 L6
chr12_-_121038967 0.97 ENST00000680620.1
ENST00000679655.1
ENST00000543677.2
OASL
2'-5'-oligoadenylate synthetase like
chr10_+_89301932 0.96 ENST00000371826.4
ENST00000679755.1
IFIT2
interferon induced protein with tetratricopeptide repeats 2
chr9_+_68356899 0.94 ENST00000396392.5
PGM5
phosphoglucomutase 5
chr20_-_49278034 0.93 ENST00000371744.5
ENST00000396105.6
ENST00000371752.5
ZNFX1
zinc finger NFX1-type containing 1
chr5_+_90640718 0.92 ENST00000640403.1
ADGRV1
adhesion G protein-coupled receptor V1
chr11_+_114060204 0.91 ENST00000683318.1
ZBTB16
zinc finger and BTB domain containing 16
chr14_-_67515153 0.87 ENST00000555994.6
TMEM229B
transmembrane protein 229B
chr3_-_45995807 0.85 ENST00000535325.5
ENST00000296137.7
FYCO1
FYVE and coiled-coil domain autophagy adaptor 1
chr2_-_162318475 0.85 ENST00000648433.1
IFIH1
interferon induced with helicase C domain 1
chr9_-_21995262 0.83 ENST00000494262.5
CDKN2A
cyclin dependent kinase inhibitor 2A
chr1_-_161631152 0.83 ENST00000421702.3
ENST00000650385.1
FCGR3B
Fc fragment of IgG receptor IIIb
chr1_-_161631032 0.82 ENST00000534776.1
ENST00000613418.4
ENST00000614870.4
FCGR3B
Fc fragment of IgG receptor IIIb
chr6_+_125919210 0.82 ENST00000438495.6
NCOA7
nuclear receptor coactivator 7
chr6_+_125919296 0.82 ENST00000444128.2
NCOA7
nuclear receptor coactivator 7
chr4_-_76023489 0.79 ENST00000306602.3
CXCL10
C-X-C motif chemokine ligand 10
chr9_-_21995301 0.79 ENST00000498628.6
CDKN2A
cyclin dependent kinase inhibitor 2A
chr7_-_140062841 0.77 ENST00000263549.8
PARP12
poly(ADP-ribose) polymerase family member 12
chr2_-_151289613 0.77 ENST00000243346.10
NMI
N-myc and STAT interactor
chr4_+_159241016 0.75 ENST00000644902.1
RAPGEF2
Rap guanine nucleotide exchange factor 2
chr17_-_42112674 0.75 ENST00000251642.8
ENST00000591220.5
DHX58
DExH-box helicase 58
chr10_+_89414555 0.74 ENST00000371795.5
ENST00000681422.1
IFIT5
interferon induced protein with tetratricopeptide repeats 5
chr9_-_33264678 0.72 ENST00000635077.1
ENST00000634734.3
BAG1
BAG cochaperone 1
chr9_-_33264559 0.68 ENST00000473781.1
ENST00000379704.7
ENST00000488499.1
BAG1
BAG cochaperone 1
chr3_+_187368367 0.65 ENST00000259030.3
RTP4
receptor transporter protein 4
chr12_-_56360084 0.63 ENST00000314128.9
ENST00000557235.5
ENST00000651915.1
STAT2
signal transducer and activator of transcription 2
chr1_-_154608140 0.59 ENST00000529168.2
ENST00000368474.9
ENST00000680305.1
ENST00000648231.2
ADAR
adenosine deaminase RNA specific
chr15_-_44711306 0.58 ENST00000682850.1
PATL2
PAT1 homolog 2
chr19_-_12696581 0.58 ENST00000587955.1
ENST00000393261.8
FBXW9
F-box and WD repeat domain containing 9
chr6_+_37433197 0.57 ENST00000455891.5
ENST00000373451.9
CMTR1
cap methyltransferase 1
chr8_-_28083920 0.55 ENST00000413272.7
NUGGC
nuclear GTPase, germinal center associated
chr3_+_122680802 0.54 ENST00000474629.7
PARP14
poly(ADP-ribose) polymerase family member 14
chr2_-_219387784 0.49 ENST00000520694.6
DNPEP
aspartyl aminopeptidase
chr1_+_236524581 0.48 ENST00000526634.5
LGALS8
galectin 8
chr6_-_33314055 0.46 ENST00000434618.7
TAPBP
TAP binding protein
chr17_+_27631148 0.46 ENST00000313648.10
ENST00000395473.7
ENST00000577392.5
ENST00000584661.5
LGALS9
galectin 9
chr13_-_42992165 0.43 ENST00000398762.7
ENST00000313640.11
ENST00000313624.12
EPSTI1
epithelial stromal interaction 1
chr3_-_121660892 0.42 ENST00000428394.6
ENST00000314583.8
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr6_-_33314386 0.41 ENST00000456592.3
TAPBP
TAP binding protein
chr1_+_220879434 0.35 ENST00000366903.8
HLX
H2.0 like homeobox
chr3_-_142448004 0.34 ENST00000463916.5
XRN1
5'-3' exoribonuclease 1
chr7_+_135148041 0.33 ENST00000275767.3
TMEM140
transmembrane protein 140
chr17_+_40140500 0.33 ENST00000264645.12
CASC3
CASC3 exon junction complex subunit
chr11_-_4393650 0.32 ENST00000254436.8
TRIM21
tripartite motif containing 21
chr7_-_105691637 0.31 ENST00000472195.1
ATXN7L1
ataxin 7 like 1
chr22_+_18150162 0.30 ENST00000215794.8
USP18
ubiquitin specific peptidase 18
chr2_+_162318884 0.29 ENST00000446271.5
ENST00000429691.6
GCA
grancalcin
chr6_-_33314247 0.28 ENST00000475304.5
ENST00000489157.5
TAPBP
TAP binding protein
chr19_+_17405685 0.28 ENST00000646744.1
ENST00000635536.2
ENST00000635060.2
ENST00000634291.2
ENST00000645298.1
ENST00000528911.5
BISPR
MVB12A
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr1_+_241532370 0.28 ENST00000366559.9
ENST00000366557.8
KMO
kynurenine 3-monooxygenase
chr4_+_145481845 0.26 ENST00000302085.9
ENST00000512019.1
SMAD1
SMAD family member 1
chr12_+_112906777 0.25 ENST00000452357.7
ENST00000445409.7
OAS1
2'-5'-oligoadenylate synthetase 1
chr3_-_142028597 0.25 ENST00000467667.5
TFDP2
transcription factor Dp-2
chr18_-_69956924 0.25 ENST00000581982.5
ENST00000280200.8
CD226
CD226 molecule
chr9_+_68356603 0.24 ENST00000396396.6
PGM5
phosphoglucomutase 5
chr12_+_112906949 0.23 ENST00000679971.1
ENST00000675868.2
ENST00000550883.2
ENST00000553152.2
ENST00000202917.10
ENST00000679467.1
ENST00000680659.1
ENST00000540589.3
ENST00000552526.2
ENST00000681228.1
ENST00000680934.1
ENST00000681700.1
ENST00000679987.1
OAS1
2'-5'-oligoadenylate synthetase 1
chr11_+_32091065 0.23 ENST00000054950.4
RCN1
reticulocalbin 1
chr22_+_41092869 0.22 ENST00000674155.1
EP300
E1A binding protein p300
chr3_-_146544850 0.21 ENST00000472349.1
PLSCR1
phospholipid scramblase 1
chr18_-_28036585 0.20 ENST00000399380.7
CDH2
cadherin 2
chr16_+_28863812 0.19 ENST00000684370.1
SH2B1
SH2B adaptor protein 1
chr17_-_4263847 0.19 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr4_-_74794514 0.17 ENST00000395743.8
BTC
betacellulin
chr3_-_146544636 0.17 ENST00000486631.5
PLSCR1
phospholipid scramblase 1
chr9_+_99906646 0.16 ENST00000259400.11
ENST00000531035.5
ENST00000525640.5
ENST00000534052.1
ENST00000526607.1
STX17
syntaxin 17
chr3_-_146544578 0.16 ENST00000342435.9
ENST00000448787.6
PLSCR1
phospholipid scramblase 1
chr3_-_146544538 0.15 ENST00000462666.5
PLSCR1
phospholipid scramblase 1
chr15_-_25863304 0.15 ENST00000555815.6
ENST00000673716.1
ATP10A
ATPase phospholipid transporting 10A (putative)
chr1_+_162632454 0.15 ENST00000367921.8
ENST00000367922.7
DDR2
discoidin domain receptor tyrosine kinase 2
chr13_-_40982880 0.14 ENST00000635415.1
ELF1
E74 like ETS transcription factor 1
chr15_+_44711487 0.12 ENST00000544417.5
ENST00000559916.1
ENST00000648006.3
B2M
beta-2-microglobulin
chr16_-_15643024 0.12 ENST00000540441.6
MARF1
meiosis regulator and mRNA stability factor 1
chr15_+_73994694 0.11 ENST00000268058.8
ENST00000395132.6
ENST00000268059.10
ENST00000354026.10
ENST00000565898.5
ENST00000569477.5
ENST00000569965.5
ENST00000567543.5
ENST00000436891.7
ENST00000435786.6
ENST00000564428.5
ENST00000359928.8
PML
PML nuclear body scaffold
chr6_-_81752671 0.11 ENST00000320172.11
ENST00000369754.7
ENST00000369756.3
TENT5A
terminal nucleotidyltransferase 5A
chr5_+_134526100 0.10 ENST00000395003.5
JADE2
jade family PHD finger 2
chr4_+_88457110 0.10 ENST00000264350.8
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr6_-_110415539 0.09 ENST00000368923.8
ENST00000368924.9
DDO
D-aspartate oxidase
chr3_-_142028617 0.09 ENST00000477292.5
ENST00000478006.5
ENST00000495310.5
ENST00000486111.5
TFDP2
transcription factor Dp-2
chr6_-_33314202 0.09 ENST00000426633.6
ENST00000467025.1
TAPBP
TAP binding protein
chr12_+_112907006 0.09 ENST00000680455.1
ENST00000551241.6
ENST00000550689.2
ENST00000679841.1
ENST00000679494.1
ENST00000553185.2
OAS1
2'-5'-oligoadenylate synthetase 1
chr19_+_17405734 0.08 ENST00000635572.1
ENST00000634675.1
ENST00000634813.1
ENST00000647283.1
ENST00000635435.2
ENST00000634731.2
ENST00000635339.1
ENST00000528604.5
BISPR
MVB12A
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr3_-_123980727 0.07 ENST00000620893.4
ROPN1
rhophilin associated tail protein 1
chr1_+_159010002 0.06 ENST00000359709.7
IFI16
interferon gamma inducible protein 16
chr20_+_62804794 0.06 ENST00000290291.10
OGFR
opioid growth factor receptor
chr1_+_159009886 0.05 ENST00000340979.10
ENST00000368131.8
ENST00000295809.12
ENST00000368132.7
IFI16
interferon gamma inducible protein 16
chr3_-_27722699 0.03 ENST00000461503.2
EOMES
eomesodermin
chr17_+_80260826 0.02 ENST00000508628.6
ENST00000582970.5
ENST00000319921.4
RNF213
ring finger protein 213
chr10_+_113679839 0.02 ENST00000369318.8
ENST00000369315.5
CASP7
caspase 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0046072 dUDP biosynthetic process(GO:0006227) dTDP biosynthetic process(GO:0006233) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dTDP metabolic process(GO:0046072) dUDP metabolic process(GO:0046077)
1.6 4.8 GO:0034769 basement membrane disassembly(GO:0034769)
1.3 4.0 GO:0006147 guanine catabolic process(GO:0006147)
1.2 6.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.2 3.6 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
1.1 21.5 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.8 2.4 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.8 3.1 GO:0036269 swimming behavior(GO:0036269)
0.7 3.3 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.7 4.0 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.5 1.4 GO:0000964 mitochondrial RNA 5'-end processing(GO:0000964) rRNA import into mitochondrion(GO:0035928)
0.5 4.5 GO:0072592 oxygen metabolic process(GO:0072592)
0.4 1.9 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.3 3.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 1.2 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.3 1.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.3 0.8 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.2 1.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.2 0.6 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.2 0.6 GO:0036451 cap mRNA methylation(GO:0036451)
0.2 1.6 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.2 7.5 GO:0035456 response to interferon-beta(GO:0035456)
0.2 2.0 GO:0043129 surfactant homeostasis(GO:0043129) positive regulation of phospholipid biosynthetic process(GO:0071073)
0.2 0.9 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 2.0 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.2 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.5 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 0.6 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.8 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.9 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 1.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.3 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 1.2 GO:0019388 galactose catabolic process(GO:0019388)
0.1 1.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 5.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0071283 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) cellular response to iron(III) ion(GO:0071283) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.0 0.2 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 1.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.3 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.6 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.8 GO:0036021 endolysosome lumen(GO:0036021)
0.5 3.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 1.9 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.8 GO:0042825 TAP complex(GO:0042825)
0.1 1.4 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 5.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 5.6 GO:0005643 nuclear pore(GO:0005643)
0.0 0.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 4.0 GO:0005811 lipid particle(GO:0005811)
0.0 14.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 5.4 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 3.2 GO:0005923 bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0004798 thymidylate kinase activity(GO:0004798)
1.3 4.0 GO:0008892 guanine deaminase activity(GO:0008892)
1.0 3.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.9 4.5 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.4 3.6 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.4 6.0 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 1.4 GO:0034046 poly(G) binding(GO:0034046)
0.2 0.6 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2 1.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 2.3 GO:0031386 protein tag(GO:0031386)
0.2 0.8 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.2 0.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 1.7 GO:0019864 IgG binding(GO:0019864)
0.1 1.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 4.8 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.7 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 2.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.5 GO:0048030 disaccharide binding(GO:0048030)
0.1 10.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 4.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 1.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 21.5 GO:0008017 microtubule binding(GO:0008017)
0.0 1.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 3.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.5 PID AP1 PATHWAY AP-1 transcription factor network
0.0 4.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID IL12 2PATHWAY IL12-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.4 4.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.4 38.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 4.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 3.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines