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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for IRX2

Z-value: 0.54

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Transcription factors associated with IRX2

Gene Symbol Gene ID Gene Info
IRX2
ENSG00000170561.13 IRX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX2hg38_v1_chr5_-_2751648_27516680.496.0e-03Click!

Activity profile of IRX2 motif

Sorted Z-values of IRX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_+_82035245 1.76 ENST00000199936.9
HSD17B2
hydroxysteroid 17-beta dehydrogenase 2
chr4_-_149815826 1.36 ENST00000636793.2
ENST00000636414.1
IQCM
IQ motif containing M
chr3_-_112846856 1.03 ENST00000488794.5
CD200R1L
CD200 receptor 1 like
chr4_+_68815991 1.02 ENST00000265403.12
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase family 2 member B10
chr22_-_35617321 0.99 ENST00000397326.7
ENST00000442617.1
MB
myoglobin
chr5_+_157269317 0.96 ENST00000618329.4
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr5_+_36608146 0.90 ENST00000381918.4
ENST00000513646.1
SLC1A3
solute carrier family 1 member 3
chr13_+_34942263 0.90 ENST00000379939.7
ENST00000400445.7
NBEA
neurobeachin
chr7_+_107044689 0.88 ENST00000265717.5
PRKAR2B
protein kinase cAMP-dependent type II regulatory subunit beta
chr10_+_125973373 0.82 ENST00000417114.5
ENST00000445510.5
ENST00000368691.5
FANK1
fibronectin type III and ankyrin repeat domains 1
chr10_-_98268186 0.79 ENST00000260702.4
LOXL4
lysyl oxidase like 4
chr13_-_46105009 0.74 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
CPB2
carboxypeptidase B2
chr17_+_7857987 0.74 ENST00000332439.5
CYB5D1
cytochrome b5 domain containing 1
chr4_-_69639642 0.74 ENST00000604629.6
ENST00000604021.1
UGT2A2
UDP glucuronosyltransferase family 2 member A2
chr1_+_162381703 0.72 ENST00000458626.4
C1orf226
chromosome 1 open reading frame 226
chr2_+_158795309 0.66 ENST00000309950.8
ENST00000621326.4
ENST00000409042.5
DAPL1
death associated protein like 1
chr4_-_38804783 0.65 ENST00000308979.7
ENST00000505940.1
ENST00000515861.5
TLR1
toll like receptor 1
chr17_+_7857695 0.64 ENST00000571846.5
CYB5D1
cytochrome b5 domain containing 1
chr3_-_122383218 0.58 ENST00000479899.5
ENST00000291458.9
ENST00000497726.5
MIX23
mitochondrial matrix import factor 23
chr14_+_75069577 0.53 ENST00000238686.8
ZC2HC1C
zinc finger C2HC-type containing 1C
chr17_-_3691887 0.52 ENST00000552050.5
P2RX5
purinergic receptor P2X 5
chr10_-_73358709 0.52 ENST00000340329.7
CFAP70
cilia and flagella associated protein 70
chr4_+_82900679 0.48 ENST00000302236.10
THAP9
THAP domain containing 9
chr7_+_150368189 0.47 ENST00000519397.1
ENST00000479668.5
REPIN1
replication initiator 1
chr14_+_75069632 0.47 ENST00000439583.2
ENST00000554763.2
ENST00000524913.3
ENST00000525046.2
ENST00000674086.1
ENST00000526130.2
ENST00000674094.1
ENST00000532198.2
ZC2HC1C
zinc finger C2HC-type containing 1C
chr5_-_88731827 0.46 ENST00000627170.2
MEF2C
myocyte enhancer factor 2C
chr4_-_69214743 0.44 ENST00000446444.2
UGT2B11
UDP glucuronosyltransferase family 2 member B11
chr1_-_206921987 0.43 ENST00000530505.1
ENST00000442471.4
FCMR
Fc fragment of IgM receptor
chr11_+_104036624 0.42 ENST00000302259.5
DDI1
DNA damage inducible 1 homolog 1
chr3_-_114624979 0.39 ENST00000676079.1
ZBTB20
zinc finger and BTB domain containing 20
chr21_-_44801769 0.38 ENST00000330942.9
UBE2G2
ubiquitin conjugating enzyme E2 G2
chr8_+_24294044 0.38 ENST00000265769.9
ADAM28
ADAM metallopeptidase domain 28
chr8_+_93754844 0.37 ENST00000684064.1
ENST00000498673.5
ENST00000518319.5
TMEM67
transmembrane protein 67
chr11_+_60280577 0.35 ENST00000679988.1
MS4A4A
membrane spanning 4-domains A4A
chr3_-_114624921 0.35 ENST00000393785.6
ZBTB20
zinc finger and BTB domain containing 20
chr18_-_55403682 0.35 ENST00000564228.5
ENST00000630828.2
TCF4
transcription factor 4
chr2_+_27148997 0.34 ENST00000296096.6
TCF23
transcription factor 23
chr12_-_91178520 0.33 ENST00000425043.5
ENST00000420120.6
ENST00000441303.6
ENST00000456569.2
DCN
decorin
chr11_+_111255982 0.31 ENST00000637637.1
C11orf53
chromosome 11 open reading frame 53
chr3_-_186544377 0.31 ENST00000307944.6
CRYGS
crystallin gamma S
chr1_-_112618204 0.31 ENST00000369664.1
ST7L
suppression of tumorigenicity 7 like
chr6_+_29396555 0.31 ENST00000623183.1
OR12D2
olfactory receptor family 12 subfamily D member 2
chr1_-_206921867 0.31 ENST00000628511.2
ENST00000367091.8
FCMR
Fc fragment of IgM receptor
chr8_+_24294107 0.31 ENST00000437154.6
ADAM28
ADAM metallopeptidase domain 28
chr4_+_188139438 0.31 ENST00000332517.4
TRIML1
tripartite motif family like 1
chr7_+_66628864 0.30 ENST00000639828.2
ENST00000275532.8
ENST00000640385.1
KCTD7
potassium channel tetramerization domain containing 7
chr19_-_35228699 0.30 ENST00000324675.3
FAM187B
family with sequence similarity 187 member B
chr7_-_105691637 0.30 ENST00000472195.1
ATXN7L1
ataxin 7 like 1
chr9_+_76459152 0.28 ENST00000444201.6
ENST00000376730.5
GCNT1
glucosaminyl (N-acetyl) transferase 1
chr20_-_56497608 0.28 ENST00000617620.1
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
chr3_+_51975026 0.27 ENST00000458031.6
ENST00000273596.8
ENST00000463937.1
ENST00000635952.1
ABHD14A
ABHD14A-ACY1
abhydrolase domain containing 14A
ABHD14A-ACY1 readthrough
chr5_+_147878703 0.27 ENST00000296694.5
SCGB3A2
secretoglobin family 3A member 2
chr6_+_30940970 0.26 ENST00000462446.6
ENST00000304311.3
MUCL3
mucin like 3
chr2_+_46617180 0.24 ENST00000238892.4
CRIPT
CXXC repeat containing interactor of PDZ3 domain
chr9_-_137302264 0.24 ENST00000356628.4
NRARP
NOTCH regulated ankyrin repeat protein
chr21_-_44801813 0.24 ENST00000345496.7
UBE2G2
ubiquitin conjugating enzyme E2 G2
chr11_+_60280531 0.24 ENST00000532114.6
MS4A4A
membrane spanning 4-domains A4A
chr1_+_166989089 0.23 ENST00000367870.6
MAEL
maelstrom spermatogenic transposon silencer
chr3_-_151384741 0.23 ENST00000302632.4
P2RY12
purinergic receptor P2Y12
chr17_-_27800524 0.22 ENST00000313735.11
NOS2
nitric oxide synthase 2
chr1_+_166989254 0.21 ENST00000367872.9
ENST00000447624.1
MAEL
maelstrom spermatogenic transposon silencer
chr3_-_11604452 0.20 ENST00000413604.5
VGLL4
vestigial like family member 4
chr7_-_151080833 0.20 ENST00000353841.6
ENST00000482571.2
FASTK
Fas activated serine/threonine kinase
chr15_+_37934626 0.20 ENST00000559502.5
ENST00000558148.5
ENST00000319669.5
ENST00000558158.5
TMCO5A
transmembrane and coiled-coil domains 5A
chr15_-_58279245 0.19 ENST00000558231.5
ALDH1A2
aldehyde dehydrogenase 1 family member A2
chr4_-_82900522 0.19 ENST00000355196.6
ENST00000507676.5
ENST00000506495.5
ENST00000507051.1
ENST00000512932.5
ENST00000509007.1
ENST00000511271.5
ENST00000504869.1
ENST00000508772.5
ENST00000513581.5
ENST00000505028.5
ENST00000503704.1
ENST00000507660.5
SEC31A
THAP9-AS1
SEC31 homolog A, COPII coat complex component
THAP9 antisense RNA 1
chr15_-_19988117 0.18 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr2_-_233013228 0.18 ENST00000264051.8
NGEF
neuronal guanine nucleotide exchange factor
chr15_-_44194407 0.18 ENST00000484674.5
FRMD5
FERM domain containing 5
chr4_-_167234266 0.17 ENST00000511269.5
ENST00000506697.5
ENST00000512042.1
SPOCK3
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr2_+_108588286 0.17 ENST00000332345.10
LIMS1
LIM zinc finger domain containing 1
chr16_+_67570741 0.17 ENST00000644753.1
ENST00000642819.1
ENST00000645306.1
CTCF
CCCTC-binding factor
chr7_-_151080787 0.16 ENST00000540185.5
ENST00000297532.11
FASTK
Fas activated serine/threonine kinase
chr19_-_38229654 0.16 ENST00000412732.5
ENST00000456296.5
DPF1
double PHD fingers 1
chr10_-_59362584 0.16 ENST00000618427.4
ENST00000611933.4
FAM13C
family with sequence similarity 13 member C
chr2_-_108989206 0.15 ENST00000258443.7
ENST00000409271.5
ENST00000376651.1
EDAR
ectodysplasin A receptor
chr3_-_58433810 0.15 ENST00000474765.1
ENST00000485460.5
ENST00000302746.11
ENST00000383714.8
PDHB
pyruvate dehydrogenase E1 subunit beta
chr16_+_33459650 0.15 ENST00000617705.1
TP53TG3F
TP53 target 3 family member F
chr7_-_5959083 0.15 ENST00000539903.5
RSPH10B
radial spoke head 10 homolog B
chr16_-_4351283 0.15 ENST00000318059.8
PAM16
presequence translocase associated motor 16
chr18_-_36122110 0.15 ENST00000586829.1
SLC39A6
solute carrier family 39 member 6
chr6_-_159045010 0.14 ENST00000338313.5
TAGAP
T cell activation RhoGTPase activating protein
chr15_+_74174403 0.14 ENST00000560862.1
ENST00000395118.1
ISLR
immunoglobulin superfamily containing leucine rich repeat
chr5_-_161546708 0.13 ENST00000393959.6
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr19_-_46654657 0.13 ENST00000300875.4
DACT3
dishevelled binding antagonist of beta catenin 3
chr10_+_100912955 0.13 ENST00000370271.7
ENST00000238961.9
ENST00000370269.3
ENST00000609386.1
SLF2
SMC5-SMC6 complex localization factor 2
chr18_+_22933819 0.13 ENST00000399722.6
ENST00000399725.6
ENST00000399721.6
RBBP8
RB binding protein 8, endonuclease
chrX_-_21658324 0.13 ENST00000379499.3
KLHL34
kelch like family member 34
chr17_+_39700046 0.13 ENST00000269571.10
ERBB2
erb-b2 receptor tyrosine kinase 2
chr7_+_95485934 0.13 ENST00000325885.6
ASB4
ankyrin repeat and SOCS box containing 4
chr13_+_102656933 0.13 ENST00000650757.1
TPP2
tripeptidyl peptidase 2
chr14_+_23321446 0.13 ENST00000216727.9
ENST00000397276.6
PABPN1
poly(A) binding protein nuclear 1
chr4_+_55395915 0.13 ENST00000506198.5
ENST00000381334.10
TMEM165
transmembrane protein 165
chr17_+_58169401 0.13 ENST00000641866.1
OR4D2
olfactory receptor family 4 subfamily D member 2
chr3_-_194351290 0.13 ENST00000429275.1
ENST00000323830.4
CPN2
carboxypeptidase N subunit 2
chr1_-_107688492 0.12 ENST00000415432.6
VAV3
vav guanine nucleotide exchange factor 3
chr19_-_38229714 0.12 ENST00000416611.5
DPF1
double PHD fingers 1
chr8_+_80485641 0.11 ENST00000430430.5
ZBTB10
zinc finger and BTB domain containing 10
chr4_-_167234426 0.11 ENST00000541354.5
ENST00000509854.5
ENST00000512681.5
ENST00000357545.9
ENST00000510741.5
ENST00000510403.5
SPOCK3
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr2_+_137964279 0.11 ENST00000329366.8
HNMT
histamine N-methyltransferase
chr17_+_997101 0.11 ENST00000327158.5
TIMM22
translocase of inner mitochondrial membrane 22
chr4_-_167234579 0.11 ENST00000502330.5
ENST00000357154.7
ENST00000421836.6
SPOCK3
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr13_-_40982880 0.11 ENST00000635415.1
ELF1
E74 like ETS transcription factor 1
chr16_-_2264221 0.10 ENST00000566397.5
RNPS1
RNA binding protein with serine rich domain 1
chrX_-_24027186 0.10 ENST00000328046.8
KLHL15
kelch like family member 15
chr16_-_69339493 0.10 ENST00000562595.5
ENST00000615447.1
ENST00000306875.10
ENST00000562081.2
COG8
component of oligomeric golgi complex 8
chr3_-_123980727 0.10 ENST00000620893.4
ROPN1
rhophilin associated tail protein 1
chr3_-_186570308 0.10 ENST00000446782.5
TBCCD1
TBCC domain containing 1
chr6_-_159044980 0.10 ENST00000367066.8
TAGAP
T cell activation RhoGTPase activating protein
chr21_+_42403856 0.09 ENST00000291535.11
UBASH3A
ubiquitin associated and SH3 domain containing A
chr17_-_5419647 0.09 ENST00000573584.6
NUP88
nucleoporin 88
chr7_-_83649097 0.09 ENST00000643230.2
SEMA3E
semaphorin 3E
chr1_-_206023889 0.09 ENST00000358184.7
ENST00000360218.3
ENST00000678712.1
ENST00000678498.1
CTSE
cathepsin E
chr20_+_18507520 0.09 ENST00000336714.8
ENST00000646240.1
ENST00000450074.6
ENST00000262544.6
SEC23B
SEC23 homolog B, COPII coat complex component
chr4_-_152411734 0.08 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7
chr1_+_215573775 0.08 ENST00000448333.1
KCTD3
potassium channel tetramerization domain containing 3
chr5_-_150758497 0.08 ENST00000521533.1
ENST00000424236.5
DCTN4
dynactin subunit 4
chr11_+_6845683 0.08 ENST00000299454.5
OR10A5
olfactory receptor family 10 subfamily A member 5
chr1_+_74235377 0.08 ENST00000326637.8
TNNI3K
TNNI3 interacting kinase
chr7_-_33100886 0.08 ENST00000448915.1
RP9
RP9 pre-mRNA splicing factor
chr11_+_77821187 0.08 ENST00000525409.5
AAMDC
adipogenesis associated Mth938 domain containing
chr6_-_159045104 0.07 ENST00000326965.7
TAGAP
T cell activation RhoGTPase activating protein
chr16_-_74607088 0.07 ENST00000565260.1
ENST00000447066.6
ENST00000205061.9
ENST00000422840.7
ENST00000627032.2
GLG1
golgi glycoprotein 1
chr1_-_157841800 0.07 ENST00000368174.5
CD5L
CD5 molecule like
chr5_-_95081482 0.07 ENST00000312216.12
ENST00000512425.5
ENST00000505208.5
ENST00000429576.6
ENST00000508509.5
ENST00000510732.5
MCTP1
multiple C2 and transmembrane domain containing 1
chr6_-_53148822 0.07 ENST00000259803.8
GCM1
glial cells missing transcription factor 1
chr4_+_113292925 0.07 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ANK2
ankyrin 2
chr16_+_56865202 0.07 ENST00000566786.5
ENST00000438926.6
ENST00000563236.6
ENST00000262502.5
SLC12A3
solute carrier family 12 member 3
chr17_+_35844077 0.07 ENST00000604694.1
TAF15
TATA-box binding protein associated factor 15
chr6_-_24489565 0.07 ENST00000230036.2
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr4_+_113292838 0.06 ENST00000672411.1
ENST00000673231.1
ANK2
ankyrin 2
chr5_-_161546671 0.06 ENST00000517547.5
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr2_+_137964446 0.06 ENST00000280096.5
ENST00000280097.5
HNMT
histamine N-methyltransferase
chr9_-_110337808 0.06 ENST00000374510.8
ENST00000374507.4
ENST00000423740.7
ENST00000374511.7
TXNDC8
thioredoxin domain containing 8
chr6_-_22302797 0.06 ENST00000651757.1
PRL
prolactin
chr5_+_73813518 0.05 ENST00000296799.8
ARHGEF28
Rho guanine nucleotide exchange factor 28
chrX_-_100874209 0.05 ENST00000372964.5
ENST00000217885.5
NOX1
NADPH oxidase 1
chr21_+_42403874 0.05 ENST00000319294.11
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr4_+_118685373 0.05 ENST00000388822.10
ENST00000508801.1
METTL14
methyltransferase like 14
chr2_-_24047375 0.05 ENST00000295148.9
WDCP
WD repeat and coiled coil containing
chr14_+_51860632 0.05 ENST00000555472.5
ENST00000556766.5
GNG2
G protein subunit gamma 2
chr9_-_35812238 0.05 ENST00000396638.7
ENST00000340291.6
SPAG8
sperm associated antigen 8
chr14_+_51860391 0.05 ENST00000335281.8
GNG2
G protein subunit gamma 2
chr2_-_46617020 0.05 ENST00000474980.1
ENST00000281382.11
ENST00000306465.8
PIGF
phosphatidylinositol glycan anchor biosynthesis class F
chr1_+_204870831 0.04 ENST00000404076.5
ENST00000539706.6
NFASC
neurofascin
chr1_+_67207614 0.04 ENST00000425614.3
IL23R
interleukin 23 receptor
chr4_-_127965930 0.04 ENST00000641447.1
ENST00000296468.8
ENST00000641134.1
ENST00000641147.1
ENST00000641178.1
MFSD8
major facilitator superfamily domain containing 8
chr19_-_41959266 0.04 ENST00000600292.5
ENST00000601078.5
ENST00000601891.5
ENST00000222008.11
RABAC1
Rab acceptor 1
chr5_+_161850597 0.04 ENST00000634335.1
ENST00000635880.1
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chr5_-_39364484 0.04 ENST00000263408.5
C9
complement C9
chr5_+_168486462 0.04 ENST00000231572.8
ENST00000626454.1
RARS1
arginyl-tRNA synthetase 1
chr10_-_47763592 0.04 ENST00000615923.4
ENST00000623662.4
ENSG00000277758.6
novel protein identical to synaptotagmin XV
chr15_+_57706725 0.03 ENST00000380557.4
ENST00000649091.1
POLR2M
RNA polymerase II subunit M
chr17_-_7857854 0.03 ENST00000333775.9
NAA38
N-alpha-acetyltransferase 38, NatC auxiliary subunit
chr4_+_48805137 0.03 ENST00000504654.5
OCIAD1
OCIA domain containing 1
chr7_+_72925075 0.03 ENST00000434423.5
POM121
POM121 transmembrane nucleoporin
chr13_-_21459253 0.03 ENST00000400590.8
ENST00000382466.7
ENST00000415724.2
ENST00000542645.5
ZDHHC20
zinc finger DHHC-type palmitoyltransferase 20
chr20_-_31390483 0.03 ENST00000376315.2
DEFB119
defensin beta 119
chr9_-_71121596 0.03 ENST00000377110.9
ENST00000377111.8
ENST00000677713.2
TRPM3
transient receptor potential cation channel subfamily M member 3
chrX_+_136536099 0.03 ENST00000440515.5
ENST00000456412.1
VGLL1
vestigial like family member 1
chr1_+_158930778 0.03 ENST00000458222.5
PYHIN1
pyrin and HIN domain family member 1
chr6_+_13272709 0.03 ENST00000379335.8
PHACTR1
phosphatase and actin regulator 1
chr8_+_97887903 0.03 ENST00000520016.5
MATN2
matrilin 2
chr19_+_18559000 0.02 ENST00000602094.5
KXD1
KxDL motif containing 1
chr5_-_180815528 0.02 ENST00000333055.8
MGAT1
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr16_+_81238682 0.02 ENST00000258168.7
ENST00000564552.1
BCO1
beta-carotene oxygenase 1
chr9_-_13175824 0.02 ENST00000545857.5
MPDZ
multiple PDZ domain crumbs cell polarity complex component
chr10_-_95069489 0.02 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
CYP2C8
cytochrome P450 family 2 subfamily C member 8
chrX_+_155997706 0.01 ENST00000369423.7
IL9R
interleukin 9 receptor
chr2_-_70293438 0.01 ENST00000482975.6
ENST00000438261.5
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr1_-_149812359 0.01 ENST00000369167.2
ENST00000545683.1
H2BC18
H2B clustered histone 18
chr9_-_21217311 0.01 ENST00000380216.1
IFNA16
interferon alpha 16
chr4_-_70839343 0.01 ENST00000514161.5
ENST00000499044.6
GRSF1
G-rich RNA sequence binding factor 1
chr7_-_108130349 0.00 ENST00000205386.8
ENST00000418464.1
ENST00000388781.8
LAMB4
laminin subunit beta 4
chr17_+_76079182 0.00 ENST00000334586.10
ZACN
zinc activated ion channel
chr1_-_173603041 0.00 ENST00000367714.4
SLC9C2
solute carrier family 9 member C2 (putative)
chr5_-_143434677 0.00 ENST00000504572.5
NR3C1
nuclear receptor subfamily 3 group C member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.2 0.7 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.9 GO:0097338 response to clozapine(GO:0097338)
0.1 1.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 1.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.9 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.5 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.6 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.2 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.2 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.1 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.0 0.5 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.3 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.4 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.4 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.1 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.2 GO:0032310 prostaglandin secretion(GO:0032310)
0.0 0.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.5 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.0 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.0 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.0 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.4 GO:0030849 autosome(GO:0030849)
0.0 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.0 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 0.6 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.5 GO:0004803 transposase activity(GO:0004803)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 1.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.5 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.7 GO:0070513 death domain binding(GO:0070513)
0.0 0.8 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 1.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.5 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.0 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis