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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for IRX3

Z-value: 1.01

Motif logo

Transcription factors associated with IRX3

Gene Symbol Gene ID Gene Info
ENSG00000177508.12 IRX3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX3hg38_v1_chr16_-_54286763_54286803-0.115.7e-01Click!

Activity profile of IRX3 motif

Sorted Z-values of IRX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_-_55833186 5.59 ENST00000361503.8
ENST00000422046.6
carboxylesterase 1
chr16_-_55833085 3.83 ENST00000360526.8
carboxylesterase 1
chr4_+_68815991 2.67 ENST00000265403.12
ENST00000458688.2
UDP glucuronosyltransferase family 2 member B10
chr4_+_69096467 2.39 ENST00000305231.12
UDP glucuronosyltransferase family 2 member B7
chr4_+_69096494 2.31 ENST00000508661.5
ENST00000622664.1
UDP glucuronosyltransferase family 2 member B7
chr10_+_116427839 2.15 ENST00000369230.4
pancreatic lipase related protein 3
chr3_+_319683 2.03 ENST00000620033.4
cell adhesion molecule L1 like
chr2_+_89936859 2.01 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr10_+_116545907 1.91 ENST00000369221.2
pancreatic lipase
chr12_-_91179355 1.80 ENST00000550563.5
ENST00000546370.5
decorin
chr12_-_70788914 1.78 ENST00000342084.8
protein tyrosine phosphatase receptor type R
chr4_-_69860138 1.65 ENST00000226444.4
sulfotransferase family 1E member 1
chr5_+_36608146 1.61 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr12_-_91180365 1.55 ENST00000547937.5
decorin
chr12_-_10130241 1.52 ENST00000353231.9
ENST00000525605.1
C-type lectin domain containing 7A
chr19_+_41088450 1.42 ENST00000330436.4
cytochrome P450 family 2 subfamily A member 13
chr4_+_69995958 1.39 ENST00000381060.2
ENST00000246895.9
statherin
chr12_-_10130143 1.37 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
C-type lectin domain containing 7A
chr5_+_140841183 1.36 ENST00000378123.4
ENST00000531613.2
protocadherin alpha 8
chr16_+_19410480 1.35 ENST00000541464.5
transmembrane channel like 5
chr9_+_87497222 1.32 ENST00000358077.9
death associated protein kinase 1
chr12_-_10130082 1.32 ENST00000533022.5
C-type lectin domain containing 7A
chr11_+_27055215 1.20 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr6_+_27138588 1.13 ENST00000615353.1
H4 clustered histone 9
chr4_+_69280472 1.08 ENST00000335568.10
ENST00000511240.1
UDP glucuronosyltransferase family 2 member B28
chr5_+_140855882 1.07 ENST00000562220.2
ENST00000307360.6
ENST00000506939.6
protocadherin alpha 10
chr12_-_91179472 1.05 ENST00000550099.5
ENST00000546391.5
decorin
chr7_-_99976017 1.04 ENST00000411734.1
ENST00000292401.9
alpha-2-glycoprotein 1, zinc-binding
chr22_-_18936142 1.01 ENST00000438924.5
ENST00000457083.1
ENST00000357068.11
ENST00000420436.5
ENST00000334029.6
ENST00000610940.4
proline dehydrogenase 1
chr2_-_89245596 0.98 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr4_-_69214743 0.90 ENST00000446444.2
UDP glucuronosyltransferase family 2 member B11
chr4_+_41359599 0.86 ENST00000513024.5
LIM and calponin homology domains 1
chr10_+_93566659 0.81 ENST00000371481.9
ENST00000371483.8
ENST00000604414.1
free fatty acid receptor 4
chr12_-_13095664 0.80 ENST00000337630.10
ENST00000545699.1
germ cell associated 1
chr7_-_93148345 0.74 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chr6_-_27831557 0.73 ENST00000611927.2
H4 clustered histone 12
chr12_+_69348372 0.71 ENST00000261267.7
ENST00000549690.1
ENST00000548839.1
lysozyme
chr6_-_52840843 0.70 ENST00000370989.6
glutathione S-transferase alpha 5
chr2_-_87825952 0.70 ENST00000398146.4
RANBP2 like and GRIP domain containing 2
chr4_-_170003738 0.70 ENST00000502832.1
ENST00000393704.3
microfibril associated protein 3 like
chr1_-_108200849 0.69 ENST00000569674.1
solute carrier family 25 member 24
chr4_-_103077282 0.68 ENST00000503230.5
ENST00000503818.1
solute carrier family 9 member B2
chr3_-_74521140 0.68 ENST00000263665.6
contactin 3
chr8_-_139654330 0.68 ENST00000647605.1
potassium two pore domain channel subfamily K member 9
chr1_-_46132616 0.67 ENST00000423209.5
ENST00000262741.10
phosphoinositide-3-kinase regulatory subunit 3
chr5_+_74715503 0.66 ENST00000513336.5
hexosaminidase subunit beta
chrX_+_7147675 0.66 ENST00000674429.1
steroid sulfatase
chrX_-_15602150 0.65 ENST00000427411.2
angiotensin I converting enzyme 2
chr6_-_47042260 0.65 ENST00000371243.2
adhesion G protein-coupled receptor F1
chr1_-_46132650 0.64 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
phosphoinositide-3-kinase regulatory subunit 3
chr1_+_158289916 0.64 ENST00000368170.8
CD1c molecule
chr19_+_50188180 0.64 ENST00000598205.5
myosin heavy chain 14
chr9_+_102995308 0.64 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
cylicin 2
chr22_+_22704265 0.63 ENST00000390307.2
immunoglobulin lambda variable 3-22
chr22_+_22818994 0.63 ENST00000390316.2
immunoglobulin lambda variable 3-9
chr4_+_41538143 0.61 ENST00000503057.6
ENST00000511496.5
LIM and calponin homology domains 1
chr14_-_106005574 0.61 ENST00000390595.3
immunoglobulin heavy variable 1-3
chr10_+_94683771 0.60 ENST00000339022.6
cytochrome P450 family 2 subfamily C member 18
chr21_-_32603237 0.60 ENST00000431599.1
cilia and flagella associated protein 298
chr4_-_88284747 0.59 ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr16_-_4788254 0.58 ENST00000591624.1
ENST00000268231.13
ENST00000396693.9
septin 12
chr14_-_105987068 0.58 ENST00000390594.3
immunoglobulin heavy variable 1-2
chr14_-_106470788 0.56 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr4_-_103076688 0.56 ENST00000394785.9
solute carrier family 9 member B2
chr4_-_87529359 0.56 ENST00000458304.2
ENST00000282470.11
SPARC like 1
chr6_+_29396555 0.55 ENST00000623183.1
olfactory receptor family 12 subfamily D member 2
chr10_+_29289061 0.55 ENST00000375500.8
ENST00000649382.2
lysozyme like 1
chrX_+_7147237 0.54 ENST00000666110.2
steroid sulfatase
chr6_+_131637296 0.54 ENST00000358229.6
ENST00000357639.8
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr2_+_106063234 0.54 ENST00000409944.5
ECRG4 augurin precursor
chr1_+_103617427 0.54 ENST00000423678.2
ENST00000414303.7
amylase alpha 2A
chr5_+_148063971 0.54 ENST00000398454.5
ENST00000359874.7
ENST00000508733.5
ENST00000256084.8
serine peptidase inhibitor Kazal type 5
chr17_-_31314066 0.53 ENST00000577894.1
ecotropic viral integration site 2B
chr16_-_20697680 0.52 ENST00000520010.6
acyl-CoA synthetase medium chain family member 1
chr7_+_143620967 0.52 ENST00000684770.1
TRPM8 channel associated factor 2
chr5_-_177780633 0.52 ENST00000513554.5
ENST00000440605.7
family with sequence similarity 153 member A
chr19_-_3500664 0.51 ENST00000427575.6
deoxyhypusine hydroxylase
chr11_+_57597563 0.50 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr8_+_22367526 0.49 ENST00000289952.9
ENST00000524285.1
solute carrier family 39 member 14
chr14_-_106185387 0.49 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr2_-_207167220 0.49 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr22_+_50738198 0.48 ENST00000216139.10
ENST00000529621.1
acrosin
chr4_+_87832917 0.47 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr11_-_111911759 0.47 ENST00000650687.2
crystallin alpha B
chr14_+_22168387 0.46 ENST00000557168.1
T cell receptor alpha variable 30
chr22_-_36160773 0.46 ENST00000531095.1
ENST00000349314.6
ENST00000397293.6
apolipoprotein L3
chr6_-_32953017 0.46 ENST00000395305.7
ENST00000374843.9
ENST00000395303.7
ENST00000429234.1
major histocompatibility complex, class II, DM alpha
novel protein
chr19_-_10380454 0.46 ENST00000530829.1
ENST00000529370.5
tyrosine kinase 2
chr19_+_37594830 0.46 ENST00000589117.5
zinc finger protein 540
chr1_+_76867469 0.45 ENST00000477717.6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr8_-_143609547 0.45 ENST00000433751.5
ENST00000495276.6
ENST00000220966.10
pyrroline-5-carboxylate reductase 3
chr10_+_89332484 0.45 ENST00000371811.4
ENST00000680037.1
ENST00000679583.1
ENST00000679897.1
interferon induced protein with tetratricopeptide repeats 3
chr13_-_46142834 0.44 ENST00000674665.1
lymphocyte cytosolic protein 1
chr11_-_65382632 0.44 ENST00000294187.10
ENST00000398802.6
ENST00000530936.1
solute carrier family 25 member 45
chr10_+_89301932 0.44 ENST00000371826.4
ENST00000679755.1
interferon induced protein with tetratricopeptide repeats 2
chr8_-_142917843 0.43 ENST00000323110.2
cytochrome P450 family 11 subfamily B member 2
chr14_-_24339951 0.43 ENST00000216274.10
receptor interacting serine/threonine kinase 3
chr2_-_182242031 0.43 ENST00000358139.6
phosphodiesterase 1A
chr12_-_10098977 0.43 ENST00000315330.8
ENST00000457018.6
C-type lectin domain family 1 member A
chr14_-_94476240 0.43 ENST00000424550.6
ENST00000337425.10
ENST00000674164.1
ENST00000546329.2
serpin family A member 9
chr14_-_51096029 0.42 ENST00000298355.7
tripartite motif containing 9
chr19_-_43883964 0.42 ENST00000587539.2
zinc finger protein 404
chr5_-_135954962 0.42 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
leukocyte cell derived chemotaxin 2
chr1_+_160739265 0.41 ENST00000368042.7
SLAM family member 7
chr2_-_232550537 0.41 ENST00000408957.7
tigger transposable element derived 1
chr11_-_4288083 0.41 ENST00000638166.1
SSU72 pseudogene 4
chr20_-_13990609 0.41 ENST00000284951.10
ENST00000378072.5
SEL1L2 adaptor subunit of ERAD E3 ligase
chr16_-_72172135 0.40 ENST00000537465.5
ENST00000237353.15
polyamine modulated factor 1 binding protein 1
chr19_-_54364908 0.40 ENST00000391742.7
leukocyte associated immunoglobulin like receptor 1
chr4_+_73740541 0.40 ENST00000401931.1
ENST00000307407.8
C-X-C motif chemokine ligand 8
chr11_+_60280577 0.39 ENST00000679988.1
membrane spanning 4-domains A4A
chr1_+_160739239 0.39 ENST00000368043.8
SLAM family member 7
chr12_+_55720405 0.39 ENST00000548082.1
retinol dehydrogenase 5
chr2_+_100974849 0.39 ENST00000450763.1
neuronal PAS domain protein 2
chr4_-_99657820 0.39 ENST00000511828.2
chromosome 4 open reading frame 54
chr20_+_56358938 0.39 ENST00000371384.4
ENST00000437418.1
family with sequence similarity 210 member B
chr21_-_32813695 0.39 ENST00000479548.2
ENST00000490358.5
chromosome 21 open reading frame 62
chr1_+_202348687 0.38 ENST00000608999.6
ENST00000391959.5
ENST00000480184.5
protein phosphatase 1 regulatory subunit 12B
chr2_-_24084292 0.38 ENST00000413037.1
ENST00000407482.5
tumor protein p53 inducible protein 3
chr12_+_55720367 0.38 ENST00000547072.5
ENST00000552930.5
ENST00000257895.10
retinol dehydrogenase 5
chr3_-_151329539 0.37 ENST00000325602.6
purinergic receptor P2Y13
chr12_-_91153149 0.37 ENST00000550758.1
decorin
chr16_-_57802401 0.37 ENST00000569112.5
ENST00000445690.7
ENST00000562311.5
ENST00000379655.8
kinesin family member C3
chr11_-_26567087 0.37 ENST00000436318.6
ENST00000281268.12
mucin 15, cell surface associated
chr3_-_65622073 0.37 ENST00000621418.4
ENST00000611645.4
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr12_+_20810698 0.37 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr20_+_2295994 0.36 ENST00000381458.6
transglutaminase 3
chr6_+_121435595 0.36 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr15_-_21742799 0.36 ENST00000622410.2
novel protein, identical to IGHV4-4
chr12_+_5432101 0.36 ENST00000423158.4
neurotrophin 3
chr1_+_202462730 0.36 ENST00000290419.9
ENST00000491336.5
protein phosphatase 1 regulatory subunit 12B
chrX_-_42778155 0.35 ENST00000378131.4
PPP1R2C family member C
chr10_-_95069489 0.35 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
cytochrome P450 family 2 subfamily C member 8
chr1_-_161367872 0.35 ENST00000367974.2
cilia and flagella associated protein 126
chr7_+_143620925 0.35 ENST00000444908.7
TRPM8 channel associated factor 2
chr14_-_106349792 0.35 ENST00000438142.3
immunoglobulin heavy variable 4-31
chr7_-_120858066 0.35 ENST00000222747.8
tetraspanin 12
chr9_-_90642855 0.35 ENST00000637905.1
DIRAS family GTPase 2
chr12_-_90955172 0.35 ENST00000358859.3
coiled-coil glutamate rich protein 1
chr1_+_220690354 0.35 ENST00000294889.6
chromosome 1 open reading frame 115
chr19_+_54497879 0.35 ENST00000412608.5
ENST00000610651.1
leukocyte associated immunoglobulin like receptor 2
chr2_+_233636502 0.34 ENST00000373445.1
UDP glucuronosyltransferase family 1 member A10
chr9_-_37465402 0.34 ENST00000307750.5
zinc finger and BTB domain containing 5
chr7_-_64982021 0.34 ENST00000610793.1
ENST00000620222.4
zinc finger protein 117
chr12_-_10453330 0.34 ENST00000347831.9
ENST00000359151.8
killer cell lectin like receptor C1
chr13_-_37598750 0.34 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr10_+_94938649 0.34 ENST00000461906.1
ENST00000260682.8
cytochrome P450 family 2 subfamily C member 9
chr16_-_67190099 0.34 ENST00000314586.11
ENST00000563889.1
ENST00000564418.1
ENST00000545725.6
exocyst complex component 3 like 1
chr14_-_106012390 0.34 ENST00000455737.2
immunoglobulin heavy variable 4-4
chr15_-_22185402 0.33 ENST00000557788.2
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr5_-_132543513 0.33 ENST00000231454.6
interleukin 5
chr3_-_191282383 0.33 ENST00000427544.6
urotensin 2B
chr19_+_3762705 0.33 ENST00000589174.1
mitochondrial ribosomal protein L54
chr2_-_157444044 0.32 ENST00000264192.8
cytohesin 1 interacting protein
chr11_-_60183011 0.32 ENST00000533023.5
ENST00000420732.6
ENST00000528851.6
membrane spanning 4-domains A6A
chr8_+_119873710 0.32 ENST00000523492.5
ENST00000286234.6
DEP domain containing MTOR interacting protein
chr12_-_101830799 0.32 ENST00000549940.5
ENST00000392919.4
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
chr6_+_30940970 0.32 ENST00000462446.6
ENST00000304311.3
mucin like 3
chr19_+_3762665 0.32 ENST00000330133.5
mitochondrial ribosomal protein L54
chr12_+_21526287 0.32 ENST00000256969.7
spexin hormone
chr1_+_160739286 0.32 ENST00000359331.8
ENST00000495334.1
SLAM family member 7
chr7_-_111562455 0.31 ENST00000452895.5
ENST00000405709.7
ENST00000452753.1
ENST00000331762.7
inner mitochondrial membrane peptidase subunit 2
chr2_+_113072318 0.31 ENST00000393197.3
interleukin 1 family member 10
chr7_+_80646305 0.31 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr5_+_141192330 0.31 ENST00000239446.6
protocadherin beta 10
chr1_+_26317950 0.31 ENST00000374213.3
CD52 molecule
chr12_-_9208388 0.31 ENST00000261336.7
PZP alpha-2-macroglobulin like
chr14_-_106025628 0.31 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr2_-_68952880 0.30 ENST00000481498.1
ENST00000328895.9
gastrokine 2
chr16_-_3443446 0.30 ENST00000301744.7
zinc finger protein 597
chr17_-_63827647 0.30 ENST00000584574.5
ENST00000585145.1
ENST00000427159.7
FtsJ RNA 2'-O-methyltransferase 3
chr22_+_50486835 0.30 ENST00000216075.11
ENST00000395732.7
myo-inositol oxygenase
chr17_+_3475959 0.30 ENST00000263080.3
aspartoacylase
chr3_-_57292676 0.30 ENST00000389601.3
ENST00000487349.6
ankyrin repeat and SOCS box containing 14
chr2_+_190927649 0.29 ENST00000409428.5
ENST00000409215.5
glutaminase
chr12_+_54854505 0.29 ENST00000308796.11
ENST00000619042.1
mucin like 1
chr6_-_55579160 0.29 ENST00000370850.6
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1
chr1_+_162497805 0.29 ENST00000538489.5
ENST00000489294.2
U2AF homology motif kinase 1
chr3_+_178419123 0.28 ENST00000614557.1
ENST00000455307.5
ENST00000436432.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript)
long intergenic non-protein coding RNA 1014
chr5_-_146922515 0.28 ENST00000508545.6
protein phosphatase 2 regulatory subunit Bbeta
chr14_-_106811131 0.28 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr13_+_21140514 0.28 ENST00000382533.8
ENST00000621421.4
Sin3A associated protein 18
chr3_-_194672175 0.28 ENST00000265245.10
large 60S subunit nuclear export GTPase 1
chr1_-_115841116 0.28 ENST00000320238.3
nescient helix-loop-helix 2
chr7_+_39566366 0.28 ENST00000448268.5
ENST00000223273.7
ENST00000432096.2
YAE1 maturation factor of ABCE1
chr10_-_35090545 0.28 ENST00000374751.7
ENST00000626172.2
cullin 2
chrX_-_34132311 0.28 ENST00000346193.5
ENST00000613251.1
family with sequence similarity 47 member A
chrX_-_6535118 0.28 ENST00000381089.7
ENST00000612369.4
ENST00000398729.1
variable charge X-linked 3A
chr4_-_144019287 0.28 ENST00000638448.1
ENST00000513128.5
ENST00000506516.6
ENST00000429670.3
ENST00000502664.6
glycophorin B (MNS blood group)
chr12_-_100267055 0.27 ENST00000551642.1
ENST00000550587.6
ENST00000416321.5
ENST00000549249.5
DEP domain containing 4
chr19_+_58305319 0.27 ENST00000413518.5
ENST00000427361.5
ENST00000610038.5
ENST00000608070.5
ENST00000609864.5
endogenous retrovirus group K3 member 1
chr19_-_23274194 0.27 ENST00000640920.1
ENST00000639997.1
ENST00000639327.1
ENST00000640517.1
ENST00000639752.1
ENST00000640354.1
ENST00000638919.1
ENST00000638822.1
ENST00000640838.1
ENST00000611392.5
ENST00000594653.1
novel transcript
zinc finger protein 724
novel transcript
chrX_+_12906639 0.27 ENST00000311912.5
toll like receptor 8
chr1_+_116754422 0.27 ENST00000369478.4
ENST00000369477.1
CD2 molecule
chr20_-_18497218 0.27 ENST00000337227.9
RB binding protein 9, serine hydrolase
chr8_-_109680812 0.27 ENST00000528716.5
ENST00000527600.5
ENST00000531230.5
ENST00000532189.5
ENST00000534184.5
ENST00000408889.7
ENST00000533171.5
syntabulin
chr12_-_21334858 0.27 ENST00000445053.1
ENST00000458504.5
ENST00000422327.5
ENST00000683939.1
solute carrier organic anion transporter family member 1A2
chr1_-_243843164 0.27 ENST00000491219.6
ENST00000680056.1
ENST00000492957.2
AKT serine/threonine kinase 3
chr12_+_10212867 0.27 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr22_+_36863091 0.27 ENST00000650698.1
neutrophil cytosolic factor 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.4 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.6 1.7 GO:0006711 estrogen catabolic process(GO:0006711)
0.3 1.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 1.8 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.3 1.4 GO:0009804 coumarin metabolic process(GO:0009804)
0.3 4.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 4.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 0.9 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.2 1.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.2 1.9 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.2 0.5 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.2 4.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.2 0.5 GO:0018874 benzoate metabolic process(GO:0018874)
0.2 0.5 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 0.5 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.4 GO:2000452 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.1 1.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.4 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 1.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.7 GO:0002005 angiotensin catabolic process in blood(GO:0002005) angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.3 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.4 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.3 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 1.4 GO:0046541 saliva secretion(GO:0046541)
0.1 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 1.9 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 0.4 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.3 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.3 GO:1990523 bone regeneration(GO:1990523)
0.1 0.2 GO:0033037 polysaccharide localization(GO:0033037)
0.1 0.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.5 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.1 0.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.4 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.7 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.1 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.5 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.7 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 0.3 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.4 GO:0019236 response to pheromone(GO:0019236)
0.1 0.9 GO:0015866 ADP transport(GO:0015866)
0.1 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.9 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.2 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.6 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.2 GO:0046021 positive regulation of transcription during mitosis(GO:0045897) regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021)
0.1 1.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.4 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 2.4 GO:0035640 exploration behavior(GO:0035640)
0.0 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.9 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.3 GO:1904304 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 1.5 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 6.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.0 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.6 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.2 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.5 GO:1903874 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 1.1 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.3 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.7 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.2 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.7 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0044241 lipid digestion(GO:0044241)
0.0 0.3 GO:0071415 cellular response to purine-containing compound(GO:0071415)
0.0 0.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.6 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.6 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.5 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.6 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.3 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.4 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.2 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.0 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.6 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 0.0 GO:0060003 copper ion export(GO:0060003)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.6 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:1903764 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0071287 cellular response to magnesium ion(GO:0071286) cellular response to manganese ion(GO:0071287)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:1905146 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) lysosomal protein catabolic process(GO:1905146)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.8 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.8 GO:0006749 glutathione metabolic process(GO:0006749)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 0.8 GO:0033150 cytoskeletal calyx(GO:0033150)
0.2 0.5 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.6 GO:0097513 myosin II filament(GO:0097513)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.4 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.2 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 2.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.2 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 1.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.3 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 11.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.5 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.4 GO:0097342 ripoptosome(GO:0097342)
0.0 2.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.8 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.9 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.4 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.5 1.4 GO:0046848 hydroxyapatite binding(GO:0046848)
0.4 1.2 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.4 1.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 1.2 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.3 1.7 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.2 8.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.4 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 4.5 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.7 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 3.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.5 GO:0004040 amidase activity(GO:0004040)
0.1 1.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 2.0 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.5 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.3 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 1.5 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.4 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.2 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.6 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.2 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.4 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.6 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.5 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 5.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.4 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 1.0 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 2.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 1.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 1.0 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.4 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 3.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 0.0 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.9 GO:0002020 protease binding(GO:0002020)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 4.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.7 ST GA13 PATHWAY G alpha 13 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 5.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 2.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants