Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for JUND
Z-value: 0.86
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Transcription factors associated with JUND
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| JUND | hg38_v1_chr19_-_18281612_18281629 | 0.20 | 2.8e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of JUND
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_-_102955705 Show fit | 2.45 |
ENST00000615555.4
ENST00000340273.4 ENST00000260302.8 |
matrix metallopeptidase 13 |
|
| chr20_+_46008900 Show fit | 1.84 |
ENST00000372330.3
|
matrix metallopeptidase 9 |
|
| chr5_-_140633167 Show fit | 1.79 |
ENST00000302014.11
|
CD14 molecule |
|
| chr5_-_140633690 Show fit | 1.79 |
ENST00000512545.1
ENST00000401743.6 |
CD14 molecule |
|
| chr15_-_74212256 Show fit | 1.51 |
ENST00000416286.7
|
signaling receptor and transporter of retinol STRA6 |
|
| chr15_-_74212219 Show fit | 1.51 |
ENST00000449139.6
|
signaling receptor and transporter of retinol STRA6 |
|
| chr12_-_119804298 Show fit | 1.47 |
ENST00000678652.1
ENST00000678494.1 |
citron rho-interacting serine/threonine kinase |
|
| chr11_-_82997477 Show fit | 1.34 |
ENST00000534301.5
|
RAB30, member RAS oncogene family |
|
| chr12_-_119803383 Show fit | 1.33 |
ENST00000392520.2
ENST00000678677.1 ENST00000679249.1 ENST00000676849.1 |
citron rho-interacting serine/threonine kinase |
|
| chr7_+_80369547 Show fit | 1.20 |
ENST00000435819.5
|
CD36 molecule |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 3.6 | GO:0071725 | toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727) |
| 0.5 | 3.0 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.0 | 2.8 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.1 | 2.2 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.5 | 1.8 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 0.2 | 1.8 | GO:2001268 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268) |
| 0.1 | 1.7 | GO:0003374 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) |
| 0.2 | 1.2 | GO:0071726 | toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) |
| 0.1 | 1.2 | GO:0034625 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 1.2 | GO:0098719 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.1 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.4 | 3.6 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.0 | 1.7 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 1.7 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 1.6 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 1.4 | GO:0015030 | Cajal body(GO:0015030) |
| 0.2 | 0.9 | GO:0030934 | anchoring collagen complex(GO:0030934) |
| 0.0 | 0.8 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.7 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.1 | 0.6 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.6 | 3.6 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
| 0.1 | 3.0 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.0 | 2.8 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.6 | 1.8 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 0.0 | 1.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.2 | 1.2 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.1 | 1.2 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 1.2 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.2 | 0.9 | GO:1990254 | keratin filament binding(GO:1990254) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.2 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 3.6 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 2.8 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 1.0 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 0.9 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 0.9 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.0 | 0.8 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.0 | 0.5 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.3 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.3 | 3.6 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.0 | 3.5 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 1.9 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 1.2 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.9 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.9 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.7 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 0.7 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |