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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for KLF12

Z-value: 1.01

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Transcription factors associated with KLF12

Gene Symbol Gene ID Gene Info
KLF12
ENSG00000118922.18 KLF12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF12hg38_v1_chr13_-_74133892_74133941-0.115.7e-01Click!

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_233195433 2.51 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase D
chr15_-_89496574 2.14 ENST00000268122.9
RHCG
Rh family C glycoprotein
chr1_-_47190013 2.01 ENST00000294338.7
PDZK1IP1
PDZK1 interacting protein 1
chr2_+_24049673 1.75 ENST00000380991.8
FKBP1B
FKBP prolyl isomerase 1B
chr2_+_24049705 1.71 ENST00000380986.9
ENST00000452109.1
FKBP1B
FKBP prolyl isomerase 1B
chrX_-_48467470 1.71 ENST00000619100.4
ENST00000622196.4
SLC38A5
solute carrier family 38 member 5
chr17_-_78903193 1.60 ENST00000322630.3
ENST00000586713.5
CEP295NL
CEP295 N-terminal like
chr16_+_69105636 1.53 ENST00000569188.6
HAS3
hyaluronan synthase 3
chr17_+_1762052 1.34 ENST00000254722.9
ENST00000576406.5
ENST00000571149.5
SERPINF1
serpin family F member 1
chr17_+_7307531 1.32 ENST00000576930.5
EIF5A
eukaryotic translation initiation factor 5A
chr20_+_46008900 1.30 ENST00000372330.3
MMP9
matrix metallopeptidase 9
chr17_+_7307602 1.29 ENST00000573542.5
ENST00000336458.13
EIF5A
eukaryotic translation initiation factor 5A
chr17_-_43022350 1.27 ENST00000587173.5
ENST00000355653.8
VAT1
vesicle amine transport 1
chr17_-_38674940 1.20 ENST00000621654.2
EPOP
elongin BC and polycomb repressive complex 2 associated protein
chr11_-_125496122 1.19 ENST00000527534.1
ENST00000278919.8
ENST00000366139.3
FEZ1
fasciculation and elongation protein zeta 1
chr18_-_34224871 1.14 ENST00000261592.10
NOL4
nucleolar protein 4
chr17_+_7307579 1.14 ENST00000572815.5
EIF5A
eukaryotic translation initiation factor 5A
chr22_+_31093358 1.13 ENST00000404574.5
SMTN
smoothelin
chr8_+_22165358 1.13 ENST00000306349.13
ENST00000306385.10
BMP1
bone morphogenetic protein 1
chr8_+_123182635 1.08 ENST00000276699.10
ENST00000522648.5
FAM83A
family with sequence similarity 83 member A
chr6_-_30684744 1.07 ENST00000615892.4
PPP1R18
protein phosphatase 1 regulatory subunit 18
chr4_-_74099187 1.05 ENST00000508487.3
CXCL2
C-X-C motif chemokine ligand 2
chr14_+_73950489 1.00 ENST00000554320.1
COQ6
coenzyme Q6, monooxygenase
chr12_-_95790755 0.98 ENST00000343702.9
ENST00000344911.8
NTN4
netrin 4
chr4_-_74038681 0.96 ENST00000296026.4
CXCL3
C-X-C motif chemokine ligand 3
chr1_+_155208690 0.93 ENST00000368376.8
MTX1
metaxin 1
chr1_+_155208727 0.92 ENST00000316721.8
MTX1
metaxin 1
chr16_+_46884675 0.89 ENST00000562132.5
ENST00000440783.2
GPT2
glutamic--pyruvic transaminase 2
chr17_+_7307961 0.87 ENST00000419711.6
ENST00000571955.5
ENST00000573714.5
EIF5A
eukaryotic translation initiation factor 5A
chr12_+_4809176 0.86 ENST00000280684.3
KCNA6
potassium voltage-gated channel subfamily A member 6
chr20_+_59577463 0.85 ENST00000359926.7
PHACTR3
phosphatase and actin regulator 3
chr18_+_58864866 0.85 ENST00000588456.5
ENST00000591808.6
ENST00000589481.1
ENST00000591049.1
ZNF532
zinc finger protein 532
chr14_+_75002903 0.84 ENST00000266126.10
EIF2B2
eukaryotic translation initiation factor 2B subunit beta
chr8_+_22165140 0.83 ENST00000397814.7
ENST00000354870.5
BMP1
bone morphogenetic protein 1
chr15_+_73926443 0.83 ENST00000261921.8
LOXL1
lysyl oxidase like 1
chr6_-_27146841 0.79 ENST00000356950.2
H2BC12
H2B clustered histone 12
chr11_-_57322197 0.78 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1
chr12_-_54384687 0.77 ENST00000550120.1
ENST00000547210.5
ENST00000394313.7
ZNF385A
zinc finger protein 385A
chr9_+_128322540 0.77 ENST00000609948.1
ENST00000608951.5
COQ4
coenzyme Q4
chr17_-_41481140 0.76 ENST00000246639.6
ENST00000393989.1
KRT35
keratin 35
chr2_-_191847068 0.75 ENST00000304141.5
CAVIN2
caveolae associated protein 2
chr17_+_59707636 0.71 ENST00000262291.9
ENST00000587945.1
ENST00000589823.6
ENST00000592106.5
ENST00000591315.5
VMP1
vacuole membrane protein 1
chr3_+_52316319 0.69 ENST00000420323.7
DNAH1
dynein axonemal heavy chain 1
chr6_+_20401864 0.68 ENST00000346618.8
ENST00000613242.4
E2F3
E2F transcription factor 3
chr2_+_9961165 0.68 ENST00000405379.6
GRHL1
grainyhead like transcription factor 1
chr1_+_50108856 0.67 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAVL4
ELAV like RNA binding protein 4
chr6_+_31927683 0.66 ENST00000456570.5
ENSG00000244255.5
novel complement component 2 (C2) and complement factor B (CFB) protein
chr22_-_37244237 0.66 ENST00000401529.3
ENST00000249071.11
RAC2
Rac family small GTPase 2
chr22_-_38302990 0.66 ENST00000612795.2
ENST00000451964.5
CSNK1E
casein kinase 1 epsilon
chr10_+_97713694 0.66 ENST00000285605.8
MARVELD1
MARVEL domain containing 1
chr3_-_48016400 0.65 ENST00000434267.5
ENST00000683076.1
ENST00000633710.1
MAP4
microtubule associated protein 4
chr1_-_155207886 0.63 ENST00000368378.7
ENST00000541990.5
ENST00000457183.6
ENST00000541576.5
THBS3
thrombospondin 3
chr1_-_18902520 0.62 ENST00000538839.5
ENST00000290597.9
ENST00000375341.8
ALDH4A1
aldehyde dehydrogenase 4 family member A1
chr12_-_66678934 0.62 ENST00000545666.5
ENST00000398016.7
ENST00000359742.9
ENST00000538211.5
GRIP1
glutamate receptor interacting protein 1
chr15_+_41493860 0.61 ENST00000260386.7
ITPKA
inositol-trisphosphate 3-kinase A
chr11_+_66593194 0.60 ENST00000310190.8
CCS
copper chaperone for superoxide dismutase
chr14_+_64704380 0.60 ENST00000247226.13
ENST00000394691.7
PLEKHG3
pleckstrin homology and RhoGEF domain containing G3
chr9_-_96302142 0.59 ENST00000648799.1
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr19_+_676385 0.58 ENST00000166139.9
FSTL3
follistatin like 3
chr14_+_85530127 0.58 ENST00000330753.6
FLRT2
fibronectin leucine rich transmembrane protein 2
chr11_+_66593171 0.58 ENST00000533244.6
CCS
copper chaperone for superoxide dismutase
chr13_-_67230313 0.57 ENST00000377865.7
PCDH9
protocadherin 9
chr20_+_50510321 0.57 ENST00000541713.5
ENST00000371621.5
PTPN1
protein tyrosine phosphatase non-receptor type 1
chr16_-_67944113 0.56 ENST00000264005.10
LCAT
lecithin-cholesterol acyltransferase
chr14_+_73950285 0.56 ENST00000334571.7
ENST00000554920.5
COQ6
coenzyme Q6, monooxygenase
chr14_+_73950252 0.55 ENST00000629426.2
COQ6
coenzyme Q6, monooxygenase
chr5_+_34656446 0.55 ENST00000428746.6
RAI14
retinoic acid induced 14
chr20_-_31845593 0.55 ENST00000375978.5
FOXS1
forkhead box S1
chr5_+_34656288 0.55 ENST00000265109.8
RAI14
retinoic acid induced 14
chrX_+_49171889 0.55 ENST00000376327.6
PLP2
proteolipid protein 2
chr9_-_96302170 0.54 ENST00000375263.8
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr19_+_44777860 0.54 ENST00000341505.4
ENST00000647358.2
CBLC
Cbl proto-oncogene C
chr14_+_51847145 0.54 ENST00000615906.4
GNG2
G protein subunit gamma 2
chr9_-_96302104 0.54 ENST00000375262.4
ENST00000650386.1
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr15_+_40470950 0.53 ENST00000306243.7
CHST14
carbohydrate sulfotransferase 14
chr7_+_143316105 0.53 ENST00000343257.7
ENST00000650516.1
CLCN1
chloride voltage-gated channel 1
chr22_-_37244417 0.52 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
RAC2
Rac family small GTPase 2
chr1_+_32222393 0.52 ENST00000676679.1
ENST00000678689.1
ENST00000373586.2
ENST00000679290.1
ENST00000677378.1
ENST00000678534.1
ENST00000678968.1
ENST00000678063.1
ENST00000678150.1
ENST00000677198.1
ENST00000677540.1
EIF3I
eukaryotic translation initiation factor 3 subunit I
chr19_-_39833615 0.52 ENST00000593685.5
ENST00000600611.5
DYRK1B
dual specificity tyrosine phosphorylation regulated kinase 1B
chr15_+_40471081 0.52 ENST00000559991.1
CHST14
carbohydrate sulfotransferase 14
chr4_+_127781815 0.51 ENST00000508776.5
HSPA4L
heat shock protein family A (Hsp70) member 4 like
chr3_+_50279080 0.51 ENST00000316436.4
LSMEM2
leucine rich single-pass membrane protein 2
chr6_+_33200820 0.51 ENST00000374675.7
SLC39A7
solute carrier family 39 member 7
chr6_+_35805347 0.50 ENST00000360215.3
LHFPL5
LHFPL tetraspan subfamily member 5
chr1_+_32222415 0.50 ENST00000678420.1
ENST00000678162.1
ENST00000678711.1
ENST00000678883.1
ENST00000677353.1
ENST00000355082.10
EIF3I
eukaryotic translation initiation factor 3 subunit I
chr11_-_66336396 0.50 ENST00000627248.1
ENST00000311320.9
RIN1
Ras and Rab interactor 1
chr8_-_142775984 0.49 ENST00000523332.5
LYNX1-SLURP2
LYNX1-SLURP2 readthrough
chr1_+_15756659 0.49 ENST00000375771.5
FBLIM1
filamin binding LIM protein 1
chr1_-_32222322 0.49 ENST00000344461.7
ENST00000373593.5
ENST00000309777.11
TMEM234
transmembrane protein 234
chr19_+_40627033 0.49 ENST00000599225.1
ENST00000598166.2
LTBP4
latent transforming growth factor beta binding protein 4
chr9_+_113444725 0.48 ENST00000374140.6
RGS3
regulator of G protein signaling 3
chr16_+_69106219 0.48 ENST00000219322.7
HAS3
hyaluronan synthase 3
chrX_-_135022473 0.48 ENST00000391440.3
RTL8B
retrotransposon Gag like 8B
chr1_-_216423396 0.46 ENST00000366942.3
ENST00000674083.1
ENST00000307340.8
USH2A
usherin
chr6_+_33200860 0.46 ENST00000374677.8
SLC39A7
solute carrier family 39 member 7
chr5_+_167754918 0.46 ENST00000519204.5
TENM2
teneurin transmembrane protein 2
chr8_-_37940103 0.46 ENST00000524298.1
ENST00000307599.5
GOT1L1
glutamic-oxaloacetic transaminase 1 like 1
chr2_-_36966471 0.45 ENST00000379213.3
STRN
striatin
chr11_-_65606959 0.45 ENST00000532507.5
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr2_-_219543793 0.45 ENST00000243776.11
CHPF
chondroitin polymerizing factor
chr14_-_106737547 0.45 ENST00000632209.1
IGHV1-69-2
immunoglobulin heavy variable 1-69-2
chr8_-_30812867 0.45 ENST00000518243.5
PPP2CB
protein phosphatase 2 catalytic subunit beta
chr4_+_70195719 0.44 ENST00000683306.1
ODAM
odontogenic, ameloblast associated
chr9_+_34652167 0.43 ENST00000441545.7
ENST00000553620.5
IL11RA
interleukin 11 receptor subunit alpha
chrX_-_132219473 0.43 ENST00000620646.4
RAP2C
RAP2C, member of RAS oncogene family
chr19_-_4558417 0.43 ENST00000586965.1
SEMA6B
semaphorin 6B
chrX_-_132219439 0.42 ENST00000370874.2
RAP2C
RAP2C, member of RAS oncogene family
chr19_-_40714938 0.42 ENST00000594490.6
ENST00000678419.1
ENST00000596357.1
ENST00000243583.10
ENST00000600080.5
ENST00000595254.5
ENST00000601967.6
ENST00000677517.1
COQ8B
coenzyme Q8B
chr4_+_127782270 0.42 ENST00000508549.5
ENST00000296464.9
HSPA4L
heat shock protein family A (Hsp70) member 4 like
chr19_+_44671722 0.42 ENST00000403660.3
CEACAM19
CEA cell adhesion molecule 19
chr19_+_44671452 0.42 ENST00000358777.9
CEACAM19
CEA cell adhesion molecule 19
chr17_+_82032182 0.42 ENST00000584341.1
RAC3
Rac family small GTPase 3
chr14_+_22281097 0.42 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr8_-_6563044 0.41 ENST00000338312.10
ANGPT2
angiopoietin 2
chr22_-_50085414 0.41 ENST00000311597.10
MLC1
modulator of VRAC current 1
chrX_-_71068311 0.41 ENST00000374274.8
SNX12
sorting nexin 12
chr17_+_82031643 0.41 ENST00000306897.9
RAC3
Rac family small GTPase 3
chr17_-_38749806 0.40 ENST00000616199.4
PCGF2
polycomb group ring finger 2
chr2_+_230878139 0.40 ENST00000620962.1
ITM2C
integral membrane protein 2C
chr19_-_45406327 0.40 ENST00000593226.5
ENST00000418234.6
PPP1R13L
protein phosphatase 1 regulatory subunit 13 like
chr1_+_92029971 0.40 ENST00000370383.5
EPHX4
epoxide hydrolase 4
chr17_+_82032061 0.40 ENST00000580965.5
RAC3
Rac family small GTPase 3
chr10_+_102395693 0.40 ENST00000652277.1
ENST00000189444.11
ENST00000661543.1
NFKB2
nuclear factor kappa B subunit 2
chr19_+_40601342 0.40 ENST00000396819.8
LTBP4
latent transforming growth factor beta binding protein 4
chr14_+_104724221 0.40 ENST00000330877.7
ADSS1
adenylosuccinate synthase 1
chr16_+_28878480 0.40 ENST00000395503.9
ATP2A1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr11_-_66593031 0.39 ENST00000333861.5
CCDC87
coiled-coil domain containing 87
chr9_-_128322407 0.38 ENST00000372890.6
TRUB2
TruB pseudouridine synthase family member 2
chr2_-_55296361 0.38 ENST00000647547.1
CCDC88A
coiled-coil domain containing 88A
chr21_-_43060546 0.38 ENST00000430013.1
CBS
cystathionine beta-synthase
chr9_-_34637719 0.38 ENST00000378892.5
ENST00000680277.1
ENST00000277010.9
ENST00000679597.1
ENST00000680244.1
SIGMAR1
sigma non-opioid intracellular receptor 1
chr16_+_28878382 0.38 ENST00000357084.7
ATP2A1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chrX_-_135052114 0.38 ENST00000370775.3
RTL8A
retrotransposon Gag like 8A
chr19_+_38390055 0.37 ENST00000587947.5
ENST00000338502.8
SPRED3
sprouty related EVH1 domain containing 3
chr19_-_39834127 0.37 ENST00000601972.1
ENST00000430012.6
ENST00000323039.10
ENST00000348817.7
DYRK1B
dual specificity tyrosine phosphorylation regulated kinase 1B
chr3_-_182985926 0.35 ENST00000487822.5
ENST00000460412.6
ENST00000469954.5
DCUN1D1
defective in cullin neddylation 1 domain containing 1
chr14_+_85530163 0.35 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr10_+_119818699 0.35 ENST00000650409.1
INPP5F
inositol polyphosphate-5-phosphatase F
chr19_-_49423441 0.35 ENST00000270631.2
PTH2
parathyroid hormone 2
chr16_-_67326729 0.35 ENST00000304372.6
KCTD19
potassium channel tetramerization domain containing 19
chrX_+_47223009 0.35 ENST00000518022.5
ENST00000276052.10
CDK16
cyclin dependent kinase 16
chrX_+_68829009 0.34 ENST00000204961.5
EFNB1
ephrin B1
chr15_-_34101807 0.33 ENST00000527822.5
ENST00000528949.1
ENST00000256545.9
EMC7
ER membrane protein complex subunit 7
chr7_+_142750657 0.33 ENST00000492062.1
PRSS1
serine protease 1
chr8_+_144012403 0.33 ENST00000447830.2
SPATC1
spermatogenesis and centriole associated 1
chr1_+_54548217 0.33 ENST00000343744.7
ENST00000371316.3
ACOT11
acyl-CoA thioesterase 11
chr17_+_18039370 0.32 ENST00000268719.9
ENST00000376345.3
GID4
GID complex subunit 4 homolog
chr11_+_65386611 0.32 ENST00000531296.1
ENST00000533782.5
ENST00000355991.9
ENST00000317568.10
ENST00000416776.6
ENST00000526201.1
FRMD8
FERM domain containing 8
chr12_-_56934403 0.32 ENST00000293502.2
SDR9C7
short chain dehydrogenase/reductase family 9C member 7
chr7_-_126533850 0.32 ENST00000444921.3
GRM8
glutamate metabotropic receptor 8
chr12_+_106774630 0.31 ENST00000392839.6
ENST00000548914.5
ENST00000355478.6
ENST00000552619.1
ENST00000549643.5
ENST00000392837.9
RIC8B
RIC8 guanine nucleotide exchange factor B
chr19_-_45768627 0.31 ENST00000560160.1
SIX5
SIX homeobox 5
chr20_-_17659917 0.31 ENST00000610403.4
RRBP1
ribosome binding protein 1
chr19_-_45496998 0.31 ENST00000245923.9
ENST00000590526.5
ENST00000344680.8
RTN2
reticulon 2
chr1_+_32817442 0.31 ENST00000373476.5
ENST00000529027.5
S100PBP
S100P binding protein
chr17_+_997101 0.31 ENST00000327158.5
TIMM22
translocase of inner mitochondrial membrane 22
chrX_+_152831054 0.31 ENST00000370274.8
NSDHL
NAD(P) dependent steroid dehydrogenase-like
chr19_+_35268921 0.31 ENST00000222305.8
ENST00000343550.9
USF2
upstream transcription factor 2, c-fos interacting
chr2_+_172860038 0.31 ENST00000538974.5
ENST00000540783.5
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr17_-_75844334 0.31 ENST00000592386.5
ENST00000412096.6
ENST00000586147.1
ENST00000207549.9
UNC13D
unc-13 homolog D
chr1_+_50109817 0.30 ENST00000652353.1
ENST00000371821.6
ENST00000652274.1
ELAVL4
ELAV like RNA binding protein 4
chr7_+_123655857 0.30 ENST00000458573.3
ENST00000456238.2
LMOD2
leiomodin 2
chr8_+_144012273 0.30 ENST00000377470.8
SPATC1
spermatogenesis and centriole associated 1
chrX_+_152917830 0.30 ENST00000318529.12
ZNF185
zinc finger protein 185 with LIM domain
chr10_+_119819244 0.30 ENST00000637174.1
INPP5F
inositol polyphosphate-5-phosphatase F
chr11_-_61581104 0.30 ENST00000263846.8
SYT7
synaptotagmin 7
chr13_+_36674013 0.29 ENST00000315190.4
SERTM1
serine rich and transmembrane domain containing 1
chr13_-_51453015 0.29 ENST00000442263.4
ENST00000311234.9
INTS6
integrator complex subunit 6
chr6_-_43053832 0.29 ENST00000265348.9
ENST00000674134.1
ENST00000674100.1
CUL7
cullin 7
chr9_-_34637800 0.28 ENST00000680730.1
ENST00000477726.1
SIGMAR1
sigma non-opioid intracellular receptor 1
chr9_-_115091018 0.28 ENST00000542877.5
ENST00000537320.5
ENST00000341037.8
TNC
tenascin C
chr14_-_21526391 0.28 ENST00000611430.4
SALL2
spalt like transcription factor 2
chr1_-_6180265 0.28 ENST00000262450.8
CHD5
chromodomain helicase DNA binding protein 5
chr2_+_184598520 0.28 ENST00000302277.7
ZNF804A
zinc finger protein 804A
chr3_+_194136138 0.28 ENST00000232424.4
HES1
hes family bHLH transcription factor 1
chr17_-_18039158 0.28 ENST00000585101.5
ENST00000474627.8
ENST00000444058.1
ATPAF2
ATP synthase mitochondrial F1 complex assembly factor 2
chr13_-_67230377 0.28 ENST00000544246.5
ENST00000377861.4
PCDH9
protocadherin 9
chr2_+_148021404 0.27 ENST00000638043.2
MBD5
methyl-CpG binding domain protein 5
chr17_-_42676980 0.27 ENST00000587627.1
ENST00000591022.6
ENST00000293349.10
PLEKHH3
pleckstrin homology, MyTH4 and FERM domain containing H3
chr1_-_148679734 0.27 ENST00000606877.2
ENST00000593495.3
NBPF14
NOTCH2NLB
NBPF member 14
notch 2 N-terminal like B
chr20_-_17660439 0.27 ENST00000246043.8
RRBP1
ribosome binding protein 1
chr3_-_100114488 0.27 ENST00000477258.2
ENST00000354552.7
ENST00000331335.9
ENST00000398326.2
FILIP1L
filamin A interacting protein 1 like
chr7_+_100676112 0.27 ENST00000412215.5
ENST00000393924.1
GNB2
G protein subunit beta 2
chr19_+_35269065 0.27 ENST00000595068.5
ENST00000379134.7
ENST00000594064.5
ENST00000598058.1
USF2
upstream transcription factor 2, c-fos interacting
chr4_-_145938775 0.27 ENST00000508784.6
ZNF827
zinc finger protein 827
chr17_-_40994159 0.27 ENST00000391586.3
KRTAP3-3
keratin associated protein 3-3
chr1_-_42740140 0.27 ENST00000372539.3
ENST00000296387.6
ENST00000539749.5
CLDN19
claudin 19
chr2_+_218880844 0.27 ENST00000258411.8
WNT10A
Wnt family member 10A
chr11_-_31810991 0.27 ENST00000640684.1
PAX6
paired box 6
chr12_+_27524151 0.26 ENST00000545334.5
ENST00000540114.5
ENST00000537927.5
ENST00000228425.11
ENST00000318304.12
ENST00000535047.5
ENST00000542629.5
PPFIBP1
PPFIA binding protein 1
chr8_-_139702998 0.26 ENST00000303015.2
KCNK9
potassium two pore domain channel subfamily K member 9
chr11_-_124320197 0.26 ENST00000624618.2
OR8D2
olfactory receptor family 8 subfamily D member 2
chr2_+_233636445 0.26 ENST00000344644.9
UGT1A10
UDP glucuronosyltransferase family 1 member A10
chr1_-_153613095 0.26 ENST00000368706.9
S100A16
S100 calcium binding protein A16
chr12_-_116881062 0.26 ENST00000550505.5
HRK
harakiri, BCL2 interacting protein
chr5_-_122078249 0.26 ENST00000231004.5
LOX
lysyl oxidase
chr17_-_59707404 0.26 ENST00000393038.3
PTRH2
peptidyl-tRNA hydrolase 2
chr6_-_30672984 0.26 ENST00000415603.1
ENST00000376442.8
DHX16
DEAH-box helicase 16
chr17_-_82840010 0.26 ENST00000269394.4
ENST00000572562.1
ZNF750
zinc finger protein 750
chr19_-_10420121 0.26 ENST00000593124.1
CDC37
cell division cycle 37, HSP90 cochaperone

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.6 2.5 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.6 4.6 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.5 2.0 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.3 3.5 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.3 0.8 GO:0031443 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.2 0.7 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.2 0.7 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.2 0.2 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.2 1.3 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.2 0.6 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 1.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.2 0.8 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 1.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
0.2 0.6 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.2 0.9 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.2 0.5 GO:0035565 regulation of pronephros size(GO:0035565)
0.2 1.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 0.7 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.2 1.3 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.2 1.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2 0.5 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 1.5 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.1 0.6 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.5 GO:1904045 cellular response to aldosterone(GO:1904045)
0.1 0.4 GO:1990927 short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.9 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 1.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 0.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 2.7 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.4 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.4 GO:0006743 ubiquinone metabolic process(GO:0006743)
0.1 0.6 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.1 0.3 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.1 0.3 GO:0045608 trochlear nerve development(GO:0021558) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.5 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 2.0 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.1 1.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.2 GO:1905064 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) negative regulation of vascular smooth muscle cell differentiation(GO:1905064) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.4 GO:0046439 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.1 0.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 1.1 GO:0015816 glycine transport(GO:0015816)
0.1 0.5 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 1.0 GO:0060346 bone trabecula formation(GO:0060346)
0.1 2.2 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.2 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.2 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 0.7 GO:0002934 desmosome organization(GO:0002934)
0.1 0.8 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.0 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.2 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.2 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.1 0.3 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.1 0.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.2 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 1.2 GO:0014041 regulation of neuron maturation(GO:0014041)
0.1 1.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.7 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.3 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:1904640 response to methionine(GO:1904640)
0.0 0.5 GO:0019532 oxalate transport(GO:0019532)
0.0 0.8 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.3 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 1.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.4 GO:0003360 brainstem development(GO:0003360)
0.0 0.7 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:2000297 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) negative regulation of synapse maturation(GO:2000297)
0.0 0.2 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.1 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912) cardiac vascular smooth muscle cell differentiation(GO:0060947)
0.0 0.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.7 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 1.2 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.7 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.3 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.4 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.3 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.6 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0 0.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.1 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.8 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 1.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.1 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.3 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.5 GO:0097264 self proteolysis(GO:0097264)
0.0 0.7 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.3 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 1.0 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.3 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.4 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.3 GO:0051715 cytolysis in other organism(GO:0051715)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 1.1 GO:0007566 embryo implantation(GO:0007566)
0.0 0.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.1 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 1.0 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.2 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.9 GO:0035904 aorta development(GO:0035904)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.6 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.0 GO:0021763 pulmonary myocardium development(GO:0003350) subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.2 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.0 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0036117 hyaluranon cable(GO:0036117)
0.3 4.6 GO:0005642 annulate lamellae(GO:0005642)
0.2 0.7 GO:0036156 inner dynein arm(GO:0036156)
0.2 0.3 GO:0014802 terminal cisterna(GO:0014802)
0.1 1.0 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.5 GO:0002139 stereocilia coupling link(GO:0002139) periciliary membrane compartment(GO:1990075)
0.1 1.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.3 GO:0043203 axon hillock(GO:0043203)
0.1 1.2 GO:0070449 elongin complex(GO:0070449)
0.1 0.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 4.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.3 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.0 0.6 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 2.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 1.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 5.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 6.0 GO:0045121 membrane raft(GO:0045121)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.4 2.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.4 2.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 0.9 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.2 1.7 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2 1.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.2 4.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 2.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.5 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.5 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 1.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.0 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 0.3 GO:0047012 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.1 0.8 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.4 GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.1 0.4 GO:0050421 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.1 0.6 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 2.6 GO:0071949 FAD binding(GO:0071949)
0.1 0.7 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.7 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.4 GO:0045499 chemorepellent activity(GO:0045499)
0.1 2.3 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.8 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.6 GO:0015266 protein channel activity(GO:0015266)
0.0 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.6 GO:0048185 activin binding(GO:0048185)
0.0 2.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 2.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 3.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.8 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 1.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.0 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 2.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 5.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.4 ST GA13 PATHWAY G alpha 13 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 2.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 4.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 2.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 2.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.6 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions