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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for KLF3
Z-value: 1.16
Motif logo
Transcription factors associated with KLF3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
KLF3
|
ENSG00000109787.13 | KLF3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| KLF3 | hg38_v1_chr4_+_38664189_38664206 | 0.14 | 4.5e-01 | Click! |
Activity profile of KLF3 motif
Sorted Z-values of KLF3 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of KLF3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 8.2 | GO:2000768 | positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
| 1.1 | 5.4 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.7 | 4.5 | GO:0010732 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 0.7 | 3.5 | GO:0072674 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.6 | 4.6 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.6 | 9.1 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
| 0.5 | 1.4 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 0.4 | 1.7 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) |
| 0.4 | 2.6 | GO:0071105 | response to interleukin-11(GO:0071105) |
| 0.4 | 1.7 | GO:0003095 | pressure natriuresis(GO:0003095) |
| 0.4 | 1.2 | GO:1902232 | regulation of positive thymic T cell selection(GO:1902232) |
| 0.3 | 4.7 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.3 | 1.1 | GO:1990166 | protein localization to site of double-strand break(GO:1990166) |
| 0.3 | 0.8 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569) |
| 0.3 | 0.8 | GO:1902960 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 0.2 | 3.2 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.2 | 0.8 | GO:1904924 | negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924) |
| 0.2 | 1.2 | GO:2000563 | positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563) |
| 0.2 | 3.4 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.2 | 1.1 | GO:0039689 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) negative regulation of histone H4-K16 acetylation(GO:2000619) |
| 0.2 | 0.6 | GO:0006117 | acetaldehyde metabolic process(GO:0006117) |
| 0.2 | 1.3 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 0.2 | 1.1 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 0.2 | 0.5 | GO:0034395 | regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) |
| 0.2 | 0.5 | GO:0061445 | endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445) |
| 0.2 | 1.8 | GO:0060235 | lens induction in camera-type eye(GO:0060235) |
| 0.1 | 0.4 | GO:0070845 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
| 0.1 | 0.3 | GO:1901523 | leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569) |
| 0.1 | 2.1 | GO:0045023 | G0 to G1 transition(GO:0045023) |
| 0.1 | 0.4 | GO:0038193 | thromboxane A2 signaling pathway(GO:0038193) |
| 0.1 | 0.9 | GO:0006050 | mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051) |
| 0.1 | 0.6 | GO:0043324 | eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) |
| 0.1 | 1.0 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.1 | 2.5 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.1 | 0.8 | GO:0043366 | beta selection(GO:0043366) |
| 0.1 | 0.5 | GO:0060296 | regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019) |
| 0.1 | 0.6 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.1 | 0.5 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 0.1 | 0.3 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
| 0.1 | 0.3 | GO:0006267 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 0.1 | 0.3 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.1 | 1.9 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
| 0.1 | 1.6 | GO:0070445 | oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) |
| 0.1 | 0.3 | GO:0036245 | cellular response to menadione(GO:0036245) |
| 0.1 | 0.1 | GO:0002125 | maternal aggressive behavior(GO:0002125) |
| 0.1 | 1.1 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.1 | 0.3 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
| 0.1 | 0.4 | GO:0042335 | cuticle development(GO:0042335) |
| 0.1 | 1.2 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.1 | 0.5 | GO:0045819 | positive regulation of glycogen catabolic process(GO:0045819) |
| 0.1 | 0.8 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.1 | 0.2 | GO:0072334 | UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334) |
| 0.1 | 1.4 | GO:0060452 | positive regulation of cardiac muscle contraction(GO:0060452) |
| 0.1 | 1.7 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.1 | 4.6 | GO:0010039 | response to iron ion(GO:0010039) |
| 0.1 | 0.3 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.1 | 0.4 | GO:1902896 | terminal web assembly(GO:1902896) |
| 0.1 | 2.4 | GO:0032098 | regulation of appetite(GO:0032098) |
| 0.1 | 0.3 | GO:1901377 | mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788) |
| 0.1 | 0.2 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 0.1 | 1.4 | GO:0035810 | positive regulation of urine volume(GO:0035810) |
| 0.1 | 0.4 | GO:0035948 | N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) |
| 0.1 | 0.8 | GO:0030473 | nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.1 | 0.6 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.1 | 0.2 | GO:0090133 | mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134) |
| 0.1 | 1.1 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.1 | 0.8 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.1 | 0.6 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
| 0.1 | 0.4 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.1 | 0.5 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 0.1 | 0.3 | GO:0009181 | purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) |
| 0.1 | 0.5 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.1 | 0.2 | GO:0033590 | response to cobalamin(GO:0033590) |
| 0.1 | 0.9 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.1 | 1.2 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.3 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
| 0.0 | 1.8 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.0 | 0.2 | GO:0072695 | negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695) |
| 0.0 | 2.7 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.2 | GO:2000360 | negative regulation of binding of sperm to zona pellucida(GO:2000360) |
| 0.0 | 0.4 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.0 | 0.2 | GO:1904862 | inhibitory synapse assembly(GO:1904862) |
| 0.0 | 0.1 | GO:0045212 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.0 | 1.6 | GO:0045730 | respiratory burst(GO:0045730) |
| 0.0 | 0.2 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) |
| 0.0 | 0.6 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.0 | 0.4 | GO:0046618 | drug export(GO:0046618) |
| 0.0 | 0.3 | GO:1901315 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 0.0 | 0.2 | GO:1904021 | negative regulation of G-protein coupled receptor internalization(GO:1904021) |
| 0.0 | 0.2 | GO:0071409 | cellular response to cycloheximide(GO:0071409) |
| 0.0 | 0.3 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.0 | 0.7 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.0 | 1.2 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.0 | 0.2 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 0.0 | 1.2 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.6 | GO:0030046 | parallel actin filament bundle assembly(GO:0030046) |
| 0.0 | 0.3 | GO:0043435 | response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
| 0.0 | 0.6 | GO:0010623 | programmed cell death involved in cell development(GO:0010623) |
| 0.0 | 0.1 | GO:0014876 | negative regulation of muscle atrophy(GO:0014736) response to injury involved in regulation of muscle adaptation(GO:0014876) |
| 0.0 | 2.8 | GO:0070206 | protein trimerization(GO:0070206) |
| 0.0 | 0.2 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 0.0 | 0.3 | GO:0072733 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 0.0 | 1.9 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
| 0.0 | 0.6 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.0 | 0.3 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.0 | 0.1 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
| 0.0 | 0.6 | GO:0016322 | neuron remodeling(GO:0016322) |
| 0.0 | 0.1 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) |
| 0.0 | 1.0 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.5 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.0 | 0.3 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.0 | 0.4 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.0 | 0.5 | GO:0045986 | negative regulation of smooth muscle contraction(GO:0045986) |
| 0.0 | 0.1 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 0.0 | 0.1 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.0 | 0.7 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.0 | 0.4 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 0.0 | 1.0 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 1.1 | GO:0043949 | regulation of cAMP-mediated signaling(GO:0043949) |
| 0.0 | 2.2 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
| 0.0 | 0.1 | GO:0038178 | complement component C5a signaling pathway(GO:0038178) |
| 0.0 | 0.2 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 0.0 | 1.8 | GO:0043303 | mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303) |
| 0.0 | 0.1 | GO:0070874 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
| 0.0 | 2.3 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 0.5 | GO:0050812 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.0 | 2.9 | GO:0009142 | nucleoside triphosphate biosynthetic process(GO:0009142) |
| 0.0 | 0.1 | GO:2000813 | negative regulation of barbed-end actin filament capping(GO:2000813) |
| 0.0 | 0.3 | GO:0042355 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.0 | 0.2 | GO:0072711 | cellular response to hydroxyurea(GO:0072711) |
| 0.0 | 0.4 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.0 | 0.5 | GO:1901673 | regulation of mitotic spindle assembly(GO:1901673) |
| 0.0 | 1.1 | GO:0061512 | protein localization to cilium(GO:0061512) |
| 0.0 | 0.6 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 0.0 | 0.1 | GO:0051612 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.0 | 0.7 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.0 | 1.7 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.1 | GO:1901731 | positive regulation of platelet aggregation(GO:1901731) regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
| 0.0 | 0.3 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.0 | 1.5 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.0 | 0.3 | GO:0006853 | carnitine shuttle(GO:0006853) |
| 0.0 | 0.5 | GO:0010745 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) |
| 0.0 | 0.3 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.0 | 0.1 | GO:0044111 | development involved in symbiotic interaction(GO:0044111) |
| 0.0 | 0.2 | GO:0003084 | positive regulation of systemic arterial blood pressure(GO:0003084) |
| 0.0 | 0.4 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.0 | 0.1 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.0 | 0.4 | GO:0006833 | water transport(GO:0006833) |
| 0.0 | 1.3 | GO:0009060 | aerobic respiration(GO:0009060) |
| 0.0 | 0.2 | GO:0032714 | negative regulation of interleukin-5 production(GO:0032714) |
| 0.0 | 0.9 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.0 | 0.2 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 0.0 | 1.2 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.6 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.0 | 0.3 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.0 | 0.1 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.0 | 0.8 | GO:0046710 | GDP metabolic process(GO:0046710) |
| 0.0 | 0.5 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
| 0.0 | 0.1 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.0 | 0.2 | GO:0010888 | negative regulation of lipid storage(GO:0010888) negative regulation of sequestering of triglyceride(GO:0010891) |
| 0.0 | 0.3 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.0 | 0.5 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.0 | 0.9 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.3 | GO:0042832 | defense response to protozoan(GO:0042832) |
| 0.0 | 0.1 | GO:0010387 | COP9 signalosome assembly(GO:0010387) |
| 0.0 | 0.2 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.0 | 0.5 | GO:0030220 | platelet formation(GO:0030220) platelet morphogenesis(GO:0036344) |
| 0.0 | 0.2 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.0 | 0.1 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.0 | 0.5 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.0 | 0.6 | GO:0045103 | intermediate filament-based process(GO:0045103) |
| 0.0 | 0.2 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.0 | 0.0 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 0.0 | 0.2 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 4.2 | GO:0002177 | manchette(GO:0002177) |
| 0.6 | 1.7 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
| 0.5 | 1.9 | GO:0097123 | cyclin A1-CDK2 complex(GO:0097123) |
| 0.4 | 7.9 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.3 | 1.6 | GO:0072534 | perineuronal net(GO:0072534) |
| 0.2 | 5.4 | GO:0036038 | MKS complex(GO:0036038) |
| 0.2 | 1.1 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 0.2 | 4.4 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.2 | 0.6 | GO:0035525 | NF-kappaB p50/p65 complex(GO:0035525) |
| 0.2 | 1.6 | GO:0032010 | phagolysosome(GO:0032010) |
| 0.1 | 1.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.1 | 0.5 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.1 | 0.3 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 0.1 | 1.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 0.3 | GO:0030312 | external encapsulating structure(GO:0030312) |
| 0.1 | 1.2 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 0.4 | GO:1990357 | terminal web(GO:1990357) |
| 0.1 | 7.3 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.1 | 2.0 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.1 | 0.9 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 1.0 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.0 | 5.4 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 4.1 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.9 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.0 | 0.5 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.0 | 0.8 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.4 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.0 | 0.8 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 0.4 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.0 | 0.3 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.0 | 0.3 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.0 | 0.8 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.7 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 1.1 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 2.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 0.1 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
| 0.0 | 8.0 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.5 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.0 | 1.3 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 0.7 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 1.0 | GO:0035267 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.0 | 0.2 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 1.0 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 0.2 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.0 | 0.1 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.0 | 0.2 | GO:0043196 | varicosity(GO:0043196) |
| 0.0 | 0.4 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.0 | 0.1 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.0 | 5.0 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 0.1 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 0.0 | 0.1 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
| 0.0 | 0.2 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 1.3 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 2.2 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 1.0 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 0.4 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.0 | 2.1 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 0.1 | GO:0036502 | Derlin-1-VIMP complex(GO:0036502) |
| 0.0 | 0.1 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 0.1 | GO:0070695 | FHF complex(GO:0070695) |
| 0.0 | 0.5 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 0.2 | GO:0071203 | WASH complex(GO:0071203) |
| 0.0 | 0.1 | GO:0032021 | NELF complex(GO:0032021) |
| 0.0 | 0.5 | GO:0030286 | dynein complex(GO:0030286) |
| 0.0 | 0.1 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.0 | 0.2 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.0 | 0.4 | GO:0005605 | basal lamina(GO:0005605) |
| 0.0 | 0.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 0.4 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 1.7 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 1.2 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.6 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.6 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.8 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 1.6 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.8 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 0.4 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.0 | 0.5 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.6 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 5.8 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
| 0.6 | 9.7 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
| 0.5 | 2.3 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
| 0.3 | 2.0 | GO:0050051 | leukotriene-B4 20-monooxygenase activity(GO:0050051) |
| 0.3 | 0.8 | GO:0005462 | UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462) |
| 0.2 | 3.2 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.2 | 1.1 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.2 | 2.3 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.2 | 0.6 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 0.2 | 0.6 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
| 0.2 | 1.7 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.2 | 1.4 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.2 | 2.6 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.1 | 0.4 | GO:0004960 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
| 0.1 | 1.9 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.1 | 0.4 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.1 | 1.1 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.1 | 1.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 1.3 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 2.2 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.1 | 0.5 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.1 | 1.2 | GO:0034485 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) |
| 0.1 | 0.5 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.1 | 0.5 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.1 | 8.6 | GO:0042805 | actinin binding(GO:0042805) |
| 0.1 | 2.7 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 0.3 | GO:0036361 | L-serine ammonia-lyase activity(GO:0003941) racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
| 0.1 | 4.6 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 1.8 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
| 0.1 | 1.6 | GO:0031701 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 0.1 | 0.2 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 0.1 | 0.3 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.1 | 0.5 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.1 | 4.0 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.1 | 3.3 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 0.5 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.1 | 2.5 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.1 | 0.4 | GO:0015307 | drug:proton antiporter activity(GO:0015307) |
| 0.1 | 0.3 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.1 | 0.3 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
| 0.1 | 0.2 | GO:0031687 | A2A adenosine receptor binding(GO:0031687) |
| 0.1 | 4.4 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 2.2 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 0.7 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 0.6 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.1 | 0.3 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.1 | 0.4 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.0 | 0.3 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
| 0.0 | 0.3 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
| 0.0 | 0.6 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.0 | 1.6 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.2 | GO:0052591 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.0 | 0.3 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 0.4 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 2.7 | GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) |
| 0.0 | 0.2 | GO:0005502 | 11-cis retinal binding(GO:0005502) |
| 0.0 | 2.2 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.3 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.0 | 1.1 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.1 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.0 | 0.4 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.0 | 0.4 | GO:0008430 | selenium binding(GO:0008430) |
| 0.0 | 2.3 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 1.2 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.3 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.0 | 0.3 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.0 | 0.1 | GO:0004878 | complement component C5a receptor activity(GO:0004878) |
| 0.0 | 0.2 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.0 | 0.5 | GO:0015250 | water channel activity(GO:0015250) |
| 0.0 | 0.1 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.0 | 1.3 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 0.8 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.3 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.0 | 0.2 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 0.0 | 0.2 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
| 0.0 | 0.1 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.0 | 0.3 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.0 | 0.1 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 0.0 | 0.3 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.0 | 0.8 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.0 | 0.2 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.0 | 1.0 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 0.3 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.0 | 2.6 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 0.5 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.0 | 0.2 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
| 0.0 | 0.6 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.2 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.0 | 0.3 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.0 | 1.1 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.2 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.0 | 0.4 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 0.8 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 1.1 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 0.6 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.3 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.0 | 0.1 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.0 | 0.6 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.0 | 0.2 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.0 | 0.8 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.3 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.0 | 0.4 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.0 | 0.2 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.0 | 0.2 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.0 | 0.5 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.0 | GO:0005415 | nucleoside:sodium symporter activity(GO:0005415) |
| 0.0 | 0.3 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.0 | 0.1 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.0 | 0.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.1 | GO:0035877 | death effector domain binding(GO:0035877) caspase binding(GO:0089720) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.7 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 1.9 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 2.7 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 3.2 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 1.3 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 1.0 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.0 | 0.5 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 2.6 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 2.4 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 3.3 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 0.5 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 2.1 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 1.0 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 2.1 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.6 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 0.4 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.1 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 1.6 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.2 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.4 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.1 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 5.6 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.1 | 1.6 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.1 | 1.6 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 2.3 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 0.4 | REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.1 | 1.1 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.1 | 1.7 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 1.9 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.1 | 0.6 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.1 | 2.0 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.7 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.0 | 1.1 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 0.6 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.0 | 0.6 | REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | Genes involved in Cyclin E associated events during G1/S transition |
| 0.0 | 1.4 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.0 | 0.4 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.0 | 2.3 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.0 | 0.3 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.0 | 0.8 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 0.9 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.4 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 0.5 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 0.1 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 1.0 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.3 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 0.0 | 0.2 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.0 | 0.3 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.3 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.0 | 0.7 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 0.8 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.4 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 0.6 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 0.2 | REACTOME OPSINS | Genes involved in Opsins |
| 0.0 | 0.9 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 1.2 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.0 | 0.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 1.1 | REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE | Genes involved in MyD88:Mal cascade initiated on plasma membrane |
| 0.0 | 0.3 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |