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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for KLF6

Z-value: 0.90

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Transcription factors associated with KLF6

Gene Symbol Gene ID Gene Info
ENSG00000067082.15 KLF6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF6hg38_v1_chr10_-_3785197_37852160.086.6e-01Click!

Activity profile of KLF6 motif

Sorted Z-values of KLF6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_73874461 2.35 ENST00000305762.11
calcium/calmodulin dependent protein kinase II gamma
chr1_+_7784411 2.05 ENST00000613533.4
ENST00000614998.4
period circadian regulator 3
chr10_+_123135938 1.88 ENST00000357878.7
H6 family homeobox 3
chr10_-_73874568 1.79 ENST00000322635.7
ENST00000322680.7
ENST00000394762.7
ENST00000680035.1
calcium/calmodulin dependent protein kinase II gamma
chr10_-_73874502 1.40 ENST00000372765.5
ENST00000351293.7
ENST00000441192.2
ENST00000423381.6
calcium/calmodulin dependent protein kinase II gamma
chr21_+_42219123 1.08 ENST00000398449.8
ATP binding cassette subfamily G member 1
chr21_+_42219111 1.06 ENST00000450121.5
ENST00000361802.6
ATP binding cassette subfamily G member 1
chr19_+_10289939 1.00 ENST00000221980.5
intercellular adhesion molecule 5
chr11_-_65872728 0.91 ENST00000528176.5
ENST00000307998.11
EGF containing fibulin extracellular matrix protein 2
chr19_-_45496998 0.80 ENST00000245923.9
ENST00000590526.5
ENST00000344680.8
reticulon 2
chr6_-_169723931 0.75 ENST00000366780.8
ENST00000612128.1
PHD finger protein 10
chr19_+_45001430 0.72 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr11_-_2885728 0.65 ENST00000647251.1
ENST00000380725.2
ENST00000430149.3
ENST00000414822.8
ENST00000440480.8
cyclin dependent kinase inhibitor 1C
chr16_+_31459479 0.65 ENST00000268314.9
armadillo repeat containing 5
chr2_-_25252072 0.64 ENST00000683760.1
DNA methyltransferase 3 alpha
chr6_-_29628038 0.64 ENST00000355973.7
ENST00000377012.8
gamma-aminobutyric acid type B receptor subunit 1
chr7_-_100177336 0.63 ENST00000292377.4
glypican 2
chr1_-_221742074 0.62 ENST00000366899.4
dual specificity phosphatase 10
chr11_-_64166102 0.62 ENST00000255681.7
ENST00000675777.1
mono-ADP ribosylhydrolase 1
chr16_-_1782526 0.61 ENST00000566339.6
splA/ryanodine receptor domain and SOCS box containing 3
chr1_+_6613722 0.61 ENST00000377648.5
PHD finger protein 13
chr16_+_31459950 0.61 ENST00000564900.1
armadillo repeat containing 5
chr19_+_45497246 0.59 ENST00000396737.6
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr1_+_37474572 0.59 ENST00000373087.7
zinc finger CCCH-type containing 12A
chr19_+_45497221 0.59 ENST00000456399.6
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr14_+_104724221 0.58 ENST00000330877.7
adenylosuccinate synthase 1
chr17_+_4807119 0.57 ENST00000263088.11
ENST00000572940.5
phospholipase D2
chr1_+_156860886 0.57 ENST00000358660.3
ENST00000675461.1
neurotrophic receptor tyrosine kinase 1
chr1_+_156860857 0.57 ENST00000524377.7
neurotrophic receptor tyrosine kinase 1
chr16_+_74999312 0.57 ENST00000566250.5
ENST00000567962.5
zinc and ring finger 1
chr1_+_156860815 0.56 ENST00000368196.7
neurotrophic receptor tyrosine kinase 1
chr7_-_143362687 0.56 ENST00000409578.5
ENST00000443739.7
ENST00000409346.5
family with sequence similarity 131 member B
chr6_-_31729785 0.54 ENST00000416410.6
dimethylarginine dimethylaminohydrolase 2
chr2_-_25252251 0.54 ENST00000380746.8
ENST00000402667.1
DNA methyltransferase 3 alpha
chr17_+_45221993 0.53 ENST00000328118.7
formin like 1
chr11_-_46918522 0.53 ENST00000378623.6
ENST00000534404.1
LDL receptor related protein 4
chr3_-_125055987 0.52 ENST00000311127.9
heart development protein with EGF like domains 1
chr11_+_118607579 0.51 ENST00000530708.4
pleckstrin homology like domain family B member 1
chr14_+_94174284 0.51 ENST00000304338.8
protein phosphatase 4 regulatory subunit 4
chr11_-_560702 0.50 ENST00000441853.5
ENST00000329451.8
lamin tail domain containing 2
chr1_+_7784251 0.49 ENST00000377532.8
ENST00000377541.5
period circadian regulator 3
chr2_-_85888958 0.49 ENST00000377332.8
ENST00000639119.1
ENST00000638572.2
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr3_+_49171590 0.48 ENST00000332780.4
kelch domain containing 8B
chr22_-_38088915 0.48 ENST00000428572.1
BAR/IMD domain containing adaptor protein 2 like 2
chr1_+_156728442 0.48 ENST00000368218.8
ENST00000368216.9
ribosomal RNA adenine dimethylase domain containing 1
chr5_+_93584916 0.48 ENST00000647447.1
ENST00000615873.1
nuclear receptor subfamily 2 group F member 1
chr13_+_31846713 0.47 ENST00000645780.1
FRY microtubule binding protein
chr14_+_94174334 0.46 ENST00000328839.3
protein phosphatase 4 regulatory subunit 4
chr10_+_97713694 0.46 ENST00000285605.8
MARVEL domain containing 1
chr19_+_48170654 0.46 ENST00000614654.2
ENST00000328759.11
zinc finger SWIM-type containing 9
chr2_-_85888685 0.46 ENST00000638178.1
ENST00000640982.1
ENST00000640992.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr2_-_25673511 0.45 ENST00000407186.5
ENST00000404103.7
ENST00000405222.5
ENST00000406818.7
ENST00000407038.7
ENST00000407661.7
ENST00000288642.12
dystrobrevin beta
chr9_+_35605234 0.45 ENST00000336395.6
testis associated actin remodelling kinase 1
chr4_-_2262082 0.45 ENST00000337190.7
MAX dimerization protein 4
chr19_-_1568301 0.45 ENST00000402693.5
mex-3 RNA binding family member D
chr2_+_69915041 0.45 ENST00000540449.5
MAX dimerization protein 1
chr7_-_27130733 0.45 ENST00000428284.2
ENST00000360046.10
ENST00000610970.1
homeobox A4
chr17_+_4833331 0.44 ENST00000355280.11
ENST00000347992.11
misshapen like kinase 1
chr9_+_35605277 0.44 ENST00000620767.4
testis associated actin remodelling kinase 1
chr11_+_63813384 0.44 ENST00000294244.9
spindlin interactor and repressor of chromatin binding
chr16_-_56425424 0.43 ENST00000290649.10
autocrine motility factor receptor
chr6_-_93419545 0.43 ENST00000369297.1
ENST00000369303.9
ENST00000680224.1
ENST00000681532.1
ENST00000679565.1
EPH receptor A7
chr19_-_48511793 0.43 ENST00000600059.6
lemur tyrosine kinase 3
chr1_-_23424692 0.43 ENST00000374601.7
ENST00000450454.7
transcription elongation factor A3
chr11_+_64234569 0.41 ENST00000309422.7
ENST00000426086.3
vascular endothelial growth factor B
chr2_+_219442023 0.41 ENST00000431523.5
ENST00000396698.5
striated muscle enriched protein kinase
chr2_+_148021001 0.41 ENST00000407073.5
methyl-CpG binding domain protein 5
chr1_+_151282262 0.41 ENST00000336715.11
ENST00000324048.9
zinc finger protein 687
chr1_-_21937300 0.40 ENST00000374695.8
heparan sulfate proteoglycan 2
chr2_-_85888897 0.40 ENST00000639305.1
ENST00000638986.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr11_+_57597563 0.40 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr5_+_136028979 0.40 ENST00000442011.7
transforming growth factor beta induced
chr1_-_44031446 0.39 ENST00000372310.8
ENST00000466926.1
solute carrier family 6 member 9
chr2_+_148021083 0.39 ENST00000642680.2
methyl-CpG binding domain protein 5
chr19_+_55339867 0.39 ENST00000255613.8
lysine methyltransferase 5C
chr3_+_50155305 0.39 ENST00000002829.8
ENST00000426511.5
semaphorin 3F
chr16_-_67968553 0.38 ENST00000576616.5
ENST00000572037.5
ENST00000316341.8
ENST00000422611.6
solute carrier family 12 member 4
chr18_-_5295679 0.38 ENST00000615385.4
ENST00000582388.5
ENST00000651870.1
zinc finger and BTB domain containing 14
chr9_+_125747345 0.38 ENST00000342287.9
ENST00000373489.10
ENST00000373487.8
PBX homeobox 3
chr9_-_107489754 0.38 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr3_+_50155024 0.38 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
semaphorin 3F
chr16_-_30123203 0.38 ENST00000395202.5
ENST00000395199.7
ENST00000263025.9
ENST00000322266.9
mitogen-activated protein kinase 3
chr11_-_64744317 0.38 ENST00000419843.1
ENST00000394430.5
RAS guanyl releasing protein 2
chr20_+_36573589 0.37 ENST00000373872.9
ENST00000650844.1
TGFB induced factor homeobox 2
chr9_-_91423819 0.37 ENST00000297689.4
nuclear factor, interleukin 3 regulated
chr11_+_57598184 0.37 ENST00000677625.1
ENST00000676670.1
serpin family G member 1
chr15_+_97960692 0.36 ENST00000268042.7
arrestin domain containing 4
chr17_-_7217206 0.36 ENST00000447163.6
ENST00000647975.1
discs large MAGUK scaffold protein 4
chr6_+_37170133 0.36 ENST00000373509.6
Pim-1 proto-oncogene, serine/threonine kinase
chr20_+_36573458 0.36 ENST00000373874.6
TGFB induced factor homeobox 2
chr5_+_79236092 0.36 ENST00000396137.5
junction mediating and regulatory protein, p53 cofactor
chr15_-_75451543 0.36 ENST00000394949.8
SIN3 transcription regulator family member A
chrX_-_129654946 0.35 ENST00000429967.3
apelin
chr6_-_110179995 0.35 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASP family member 1
chr2_+_69915100 0.35 ENST00000264444.7
MAX dimerization protein 1
chr9_-_37465402 0.35 ENST00000307750.5
zinc finger and BTB domain containing 5
chr10_-_43267059 0.35 ENST00000395810.6
RasGEF domain family member 1A
chr19_+_49581304 0.35 ENST00000246794.10
proline rich and Gla domain 2
chr5_+_38846002 0.34 ENST00000274276.8
oncostatin M receptor
chr6_-_31958935 0.34 ENST00000441998.5
ENST00000444811.6
ENST00000375429.8
negative elongation factor complex member E
chr19_+_41354145 0.34 ENST00000604123.5
transmembrane protein 91
chr10_+_97498881 0.34 ENST00000370664.4
ubiquitin domain containing 1
chr2_-_96116565 0.34 ENST00000620793.2
adrenoceptor alpha 2B
chr22_+_41381923 0.34 ENST00000266304.9
TEF transcription factor, PAR bZIP family member
chr5_+_38845824 0.33 ENST00000502536.5
oncostatin M receptor
chr1_-_113812254 0.33 ENST00000616024.4
ENST00000615321.1
round spermatid basic protein 1
chr8_-_100309904 0.33 ENST00000523481.5
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr5_-_135535955 0.33 ENST00000314744.6
neurogenin 1
chr6_-_31958852 0.33 ENST00000375425.9
ENST00000426722.5
negative elongation factor complex member E
chr6_+_21593742 0.33 ENST00000244745.4
SRY-box transcription factor 4
chr6_-_170291053 0.33 ENST00000366756.4
delta like canonical Notch ligand 1
chr11_+_119168705 0.33 ENST00000409109.6
ENST00000409991.5
ENST00000292199.6
NLR family member X1
chr6_-_159727324 0.33 ENST00000401980.3
ENST00000545162.5
superoxide dismutase 2
chr7_-_143408848 0.33 ENST00000275815.4
EPH receptor A1
chr17_-_7217178 0.32 ENST00000485100.5
discs large MAGUK scaffold protein 4
chr6_+_82364234 0.32 ENST00000543496.3
trophoblast glycoprotein
chr11_-_12009082 0.32 ENST00000396505.7
dickkopf WNT signaling pathway inhibitor 3
chr1_+_210329294 0.32 ENST00000367010.5
hedgehog acyltransferase
chr4_-_36244438 0.32 ENST00000303965.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_+_119168188 0.32 ENST00000454811.5
ENST00000409265.8
ENST00000449394.5
NLR family member X1
chr20_-_31870216 0.32 ENST00000486996.5
ENST00000398084.6
dual specificity phosphatase 15
chr16_-_57536543 0.32 ENST00000258214.3
coiled-coil domain containing 102A
chr16_-_30122944 0.32 ENST00000484663.5
ENST00000478356.5
mitogen-activated protein kinase 3
chr11_-_1622093 0.32 ENST00000616115.1
ENST00000399682.1
keratin associated protein 5-4
chr5_-_148654522 0.31 ENST00000377888.8
5-hydroxytryptamine receptor 4
chr16_+_68645290 0.31 ENST00000264012.9
cadherin 3
chr11_+_68460712 0.31 ENST00000528635.5
ENST00000533127.5
ENST00000529907.5
ENST00000529344.5
ENST00000534534.5
ENST00000524845.5
ENST00000393800.7
ENST00000265637.8
ENST00000524904.5
ENST00000393801.7
ENST00000265636.9
ENST00000529710.5
protein phosphatase 6 regulatory subunit 3
chr17_+_72121012 0.31 ENST00000245479.3
SRY-box transcription factor 9
chr1_-_44031352 0.31 ENST00000372306.7
ENST00000475075.6
solute carrier family 6 member 9
chr17_-_44363839 0.31 ENST00000293443.12
family with sequence similarity 171 member A2
chr20_-_57710001 0.31 ENST00000341744.8
prostate transmembrane protein, androgen induced 1
chr6_-_110179702 0.30 ENST00000392587.6
WASP family member 1
chr1_-_35557378 0.30 ENST00000325722.8
ENST00000469892.5
KIAA0319 like
chr7_-_99144053 0.30 ENST00000361125.1
ENST00000361368.7
SMAD specific E3 ubiquitin protein ligase 1
chr11_+_111602380 0.30 ENST00000304987.4
salt inducible kinase 2
chr8_+_26383043 0.30 ENST00000380629.7
BCL2 interacting protein 3 like
chr17_-_181640 0.30 ENST00000613549.3
double C2 domain beta
chr15_-_60592507 0.29 ENST00000449337.6
RAR related orphan receptor A
chr1_-_32362081 0.29 ENST00000432622.1
family with sequence similarity 229 member A
chr17_+_76736530 0.29 ENST00000621483.4
major facilitator superfamily domain containing 11
chr6_-_44265541 0.28 ENST00000619360.6
NFKB inhibitor epsilon
chr11_+_62613236 0.28 ENST00000278833.4
retinal outer segment membrane protein 1
chr19_-_1401487 0.28 ENST00000640762.1
ENST00000252288.8
ENST00000447102.8
guanidinoacetate N-methyltransferase
chr19_+_42284020 0.28 ENST00000160740.7
capicua transcriptional repressor
chr19_+_35000426 0.28 ENST00000411896.6
ENST00000424536.2
GRAM domain containing 1A
chr11_+_94973640 0.28 ENST00000335080.6
ENST00000536741.1
lysine demethylase 4D
chr2_+_48440757 0.28 ENST00000294952.13
ENST00000281394.8
ENST00000449090.6
protein phosphatase 1 regulatory subunit 21
chr2_+_30146941 0.28 ENST00000379520.7
ENST00000379519.7
yippee like 5
chr12_-_94650506 0.27 ENST00000261226.9
transmembrane and coiled-coil domain family 3
chr9_+_34958254 0.27 ENST00000242315.3
PHD finger protein 24
chr6_+_31959130 0.27 ENST00000375394.7
ENST00000628157.1
Ski2 like RNA helicase
chr8_-_22232020 0.27 ENST00000454243.7
ENST00000321613.7
phytanoyl-CoA 2-hydroxylase interacting protein
chr1_+_226223618 0.27 ENST00000542034.5
ENST00000366810.6
Mix paired-like homeobox
chr13_+_97434154 0.27 ENST00000245304.5
RAP2A, member of RAS oncogene family
chrX_+_151694967 0.26 ENST00000448726.5
ENST00000538575.5
proline rich and Gla domain 3
chr3_+_124584625 0.26 ENST00000291478.9
ENST00000682363.1
ENST00000454902.1
kalirin RhoGEF kinase
chr19_+_531750 0.26 ENST00000215574.9
cell division cycle 34, ubiqiutin conjugating enzyme
chr7_-_140478926 0.26 ENST00000480552.5
makorin ring finger protein 1
chr11_-_45665578 0.26 ENST00000308064.7
carbohydrate sulfotransferase 1
chr22_+_37608826 0.26 ENST00000405147.7
ENST00000343632.9
ENST00000429218.5
ENST00000325180.12
golgi associated, gamma adaptin ear containing, ARF binding protein 1
chr20_+_58891704 0.26 ENST00000371081.5
ENST00000338783.7
GNAS complex locus
chr5_-_126595237 0.26 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr11_+_118607598 0.26 ENST00000600882.6
ENST00000356063.9
pleckstrin homology like domain family B member 1
chr16_+_68644988 0.26 ENST00000429102.6
cadherin 3
chr9_+_125748175 0.26 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr2_+_46941199 0.26 ENST00000319190.11
ENST00000394850.6
tetratricopeptide repeat domain 7A
chr5_+_109689915 0.26 ENST00000261483.5
mannosidase alpha class 2A member 1
chr5_-_126595185 0.26 ENST00000510111.6
ENST00000635851.1
ENST00000637964.1
ENST00000413020.6
ENST00000637782.1
ENST00000409134.8
ENST00000637272.1
ENST00000636879.1
ENST00000636743.1
ENST00000636886.1
ENST00000509270.2
aldehyde dehydrogenase 7 family member A1
chr11_-_63768762 0.25 ENST00000433688.2
chromosome 11 open reading frame 95
chr12_+_53380141 0.25 ENST00000551969.5
ENST00000327443.9
Sp1 transcription factor
chr5_-_159209503 0.25 ENST00000424310.7
ENST00000611185.4
ring finger protein 145
chr11_-_417304 0.25 ENST00000397632.7
single Ig and TIR domain containing
chr1_-_114153863 0.25 ENST00000610222.3
ENST00000369547.6
ENST00000641643.2
synaptotagmin 6
chr19_+_47256518 0.25 ENST00000643617.1
ENST00000221922.11
coiled-coil domain containing 9
chr15_-_70096604 0.25 ENST00000559048.5
ENST00000560939.5
ENST00000440567.7
ENST00000557907.5
ENST00000558379.5
ENST00000559929.5
TLE family member 3, transcriptional corepressor
chr2_-_218568291 0.25 ENST00000418019.5
ENST00000454775.5
ENST00000338465.5
ENST00000415516.5
ENST00000258399.8
ubiquitin specific peptidase 37
chr17_-_2025289 0.25 ENST00000331238.7
reticulon 4 receptor like 1
chr6_+_72622086 0.25 ENST00000370392.5
ENST00000629977.2
potassium voltage-gated channel subfamily Q member 5
chr17_+_63477052 0.24 ENST00000290866.10
ENST00000428043.5
angiotensin I converting enzyme
chr1_-_20486197 0.24 ENST00000375078.4
calcium/calmodulin dependent protein kinase II inhibitor 1
chr19_+_4153616 0.24 ENST00000078445.7
ENST00000595923.5
ENST00000602257.5
ENST00000602147.1
cAMP responsive element binding protein 3 like 3
chr20_-_31870510 0.24 ENST00000339738.10
dual specificity phosphatase 15
chr17_-_21253398 0.24 ENST00000611551.1
N-acetyltransferase domain containing 1
chr19_-_4124082 0.24 ENST00000394867.8
ENST00000262948.10
mitogen-activated protein kinase kinase 2
chr15_-_55743086 0.24 ENST00000561292.1
ENST00000389286.9
protogenin
chr2_+_219418369 0.24 ENST00000373960.4
desmin
chr3_-_123449083 0.24 ENST00000462833.6
adenylate cyclase 5
chrX_+_54808359 0.24 ENST00000375058.5
ENST00000375060.5
MAGE family member D2
chr7_-_27130182 0.24 ENST00000511914.1
homeobox A4
chr18_+_62523002 0.24 ENST00000269499.10
zinc finger CCHC-type containing 2
chr9_+_126914844 0.24 ENST00000373436.5
Ral GEF with PH domain and SH3 binding motif 1
chr1_-_113812448 0.24 ENST00000612242.4
ENST00000261441.9
round spermatid basic protein 1
chr14_-_99480784 0.24 ENST00000329331.7
ENST00000436070.6
SET domain containing 3, actin histidine methyltransferase
chr10_+_100997040 0.24 ENST00000370223.7
leucine zipper tumor suppressor 2
chr11_-_72642450 0.23 ENST00000444035.6
ENST00000544570.5
phosphodiesterase 2A
chr1_+_32886456 0.23 ENST00000373467.4
hippocalcin
chr10_+_87863595 0.23 ENST00000371953.8
phosphatase and tensin homolog
chrX_+_48508949 0.23 ENST00000359882.8
ENST00000326194.11
ENST00000355961.8
ENST00000683923.1
ENST00000489940.5
ENST00000361988.7
porcupine O-acyltransferase
chr17_-_63700100 0.23 ENST00000578993.5
ENST00000259006.8
ENST00000583211.5
LIM domain containing 2
chr7_+_92245960 0.23 ENST00000265742.8
ankyrin repeat and IBR domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0009720 detection of hormone stimulus(GO:0009720)
0.3 1.7 GO:0021553 olfactory nerve development(GO:0021553)
0.3 0.8 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 5.7 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.2 0.7 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 0.6 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.2 1.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.2 0.6 GO:1902908 negative regulation of transforming growth factor beta2 production(GO:0032912) negative regulation of hair follicle maturation(GO:0048817) regulation of melanosome transport(GO:1902908)
0.2 1.1 GO:0007386 compartment pattern specification(GO:0007386)
0.2 0.5 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.2 0.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 0.6 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.2 0.3 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.4 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.3 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.5 GO:0061360 optic nerve formation(GO:0021634) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.1 0.9 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.8 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.5 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.4 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.5 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.4 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.1 0.6 GO:0010587 miRNA catabolic process(GO:0010587) negative regulation by host of viral genome replication(GO:0044828) response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.8 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.3 GO:0071626 mastication(GO:0071626) learned vocalization behavior(GO:0098583) negative regulation of relaxation of muscle(GO:1901078)
0.1 0.4 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.8 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 0.4 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.2 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.1 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.2 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 1.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 1.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.2 GO:0097107 postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.2 GO:0034970 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R2 methylation(GO:0034970)
0.1 2.7 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 0.4 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.1 0.2 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.2 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 0.6 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.3 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.3 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1 0.2 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.2 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.1 0.2 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.2 GO:0036482 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.1 0.7 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.2 GO:1903984 rhythmic synaptic transmission(GO:0060024) negative regulation of ribosome biogenesis(GO:0090071) regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.4 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 0.2 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.3 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.2 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.2 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.8 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.2 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 0.5 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:0046668 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) regulation of retinal cell programmed cell death(GO:0046668) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.2 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.4 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.3 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.2 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.4 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.8 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.2 GO:1904782 negative regulation of glutamate receptor signaling pathway(GO:1900450) negative regulation of NMDA glutamate receptor activity(GO:1904782)
0.0 0.2 GO:1902075 cellular response to salt(GO:1902075)
0.0 1.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.4 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.2 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.5 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.7 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.3 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.3 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.2 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:1901254 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:1900163 regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
0.0 1.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.3 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.5 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.3 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.2 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.7 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 2.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.1 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.0 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.0 0.1 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.3 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.2 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.4 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0060434 bronchus morphogenesis(GO:0060434)
0.0 0.5 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619) negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0032525 negative regulation of neuron maturation(GO:0014043) somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:1903294 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.2 GO:0048672 regulation of collateral sprouting(GO:0048670) positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.2 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.2 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.0 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.4 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 1.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.1 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.2 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.2 0.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.8 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.8 GO:0032021 NELF complex(GO:0032021)
0.1 0.4 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 5.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 1.5 GO:0001741 XY body(GO:0001741)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.2 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.1 0.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.8 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.9 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.8 GO:0045180 basal cortex(GO:0045180)
0.0 0.9 GO:0010369 chromocenter(GO:0010369)
0.0 0.7 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.5 GO:0032059 bleb(GO:0032059)
0.0 0.5 GO:0071439 clathrin complex(GO:0071439)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0097413 Lewy body(GO:0097413)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 3.2 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.4 5.0 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.3 1.3 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.3 1.7 GO:0005166 neurotrophin p75 receptor binding(GO:0005166) nerve growth factor receptor activity(GO:0010465)
0.2 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 0.7 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.4 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.8 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.8 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0051800 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.4 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.4 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.2 GO:0070364 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.2 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0031711 peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.6 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.5 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.2 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 2.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0097001 glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001)
0.0 0.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 1.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.2 GO:0022821 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0 0.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.9 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 ST GAQ PATHWAY G alpha q Pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 2.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism