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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for LEF1

Z-value: 1.06

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Transcription factors associated with LEF1

Gene Symbol Gene ID Gene Info
ENSG00000138795.10 LEF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LEF1hg38_v1_chr4_-_108167784_108167890,
hg38_v1_chr4_-_108166715_108166726
-0.291.1e-01Click!

Activity profile of LEF1 motif

Sorted Z-values of LEF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LEF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_138179093 1.72 ENST00000394894.8
kinesin family member 20A
chr5_+_138179145 1.72 ENST00000508792.5
ENST00000504621.1
kinesin family member 20A
chr3_+_19148500 1.67 ENST00000328405.7
potassium voltage-gated channel subfamily H member 8
chr2_-_1744442 1.66 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
peroxidasin
chr3_-_142029108 1.60 ENST00000497579.5
transcription factor Dp-2
chr3_-_71130557 1.42 ENST00000497355.7
forkhead box P1
chr14_+_54397021 1.35 ENST00000541304.5
cyclin dependent kinase inhibitor 3
chr7_-_41703062 1.32 ENST00000242208.5
inhibin subunit beta A
chr14_+_54396949 1.31 ENST00000611205.4
cyclin dependent kinase inhibitor 3
chrX_+_38561530 1.31 ENST00000378482.7
ENST00000286824.6
tetraspanin 7
chr3_-_112641292 1.30 ENST00000439685.6
coiled-coil domain containing 80
chr14_+_54396964 1.30 ENST00000543789.6
ENST00000442975.6
ENST00000458126.6
ENST00000556102.6
ENST00000335183.11
cyclin dependent kinase inhibitor 3
chr3_-_71130963 1.25 ENST00000649695.2
forkhead box P1
chr1_-_205449924 1.23 ENST00000367154.5
LEM domain containing 1
chr9_+_98943898 1.19 ENST00000375001.8
collagen type XV alpha 1 chain
chr7_+_120988683 1.09 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr3_-_33645253 1.09 ENST00000333778.10
cytoplasmic linker associated protein 2
chr3_-_112641128 1.08 ENST00000206423.8
coiled-coil domain containing 80
chr1_-_205455954 1.07 ENST00000495594.2
ENST00000629624.2
LEM domain containing 1
bladder cancer associated transcript 1
chr9_+_98943705 1.01 ENST00000610452.1
collagen type XV alpha 1 chain
chr5_-_147453888 1.00 ENST00000398514.7
dihydropyrimidinase like 3
chr20_+_38926312 1.00 ENST00000619304.4
ENST00000619850.2
family with sequence similarity 83 member D
chr1_+_81800368 1.00 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr11_-_75306688 0.97 ENST00000532525.1
arrestin beta 1
chr7_-_148884266 0.96 ENST00000483967.5
ENST00000320356.7
enhancer of zeste 2 polycomb repressive complex 2 subunit
chrX_-_48470243 0.92 ENST00000429543.2
ENST00000620913.5
solute carrier family 38 member 5
chr15_-_74202742 0.91 ENST00000395105.9
signaling receptor and transporter of retinol STRA6
chrX_-_48470163 0.91 ENST00000595796.5
solute carrier family 38 member 5
chr7_-_148884159 0.90 ENST00000478654.5
ENST00000460911.5
ENST00000350995.6
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr9_-_23826299 0.89 ENST00000380117.5
ELAV like RNA binding protein 2
chr8_-_123541197 0.89 ENST00000517956.5
ENST00000443022.2
F-box protein 32
chr5_+_162068031 0.81 ENST00000356592.8
gamma-aminobutyric acid type A receptor subunit gamma2
chrY_-_13479938 0.80 ENST00000382893.2
ENST00000382896.9
ENST00000545955.6
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr1_-_226309071 0.80 ENST00000359525.2
ENST00000681046.1
ENST00000460719.5
lin-9 DREAM MuvB core complex component
chr5_+_162067858 0.80 ENST00000361925.9
gamma-aminobutyric acid type A receptor subunit gamma2
chr5_+_162067990 0.78 ENST00000641017.1
gamma-aminobutyric acid type A receptor subunit gamma2
chr3_+_39467672 0.77 ENST00000436143.6
ENST00000441980.6
ENST00000682069.1
ENST00000311042.10
myelin associated oligodendrocyte basic protein
chr10_+_52314272 0.77 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr2_+_232870284 0.75 ENST00000331342.4
secondary ossification center associated regulator of chondrocyte maturation
chr6_+_99606833 0.75 ENST00000369215.5
PR/SET domain 13
chr7_+_28412511 0.75 ENST00000357727.7
cAMP responsive element binding protein 5
chr3_-_71304741 0.74 ENST00000484350.5
forkhead box P1
chr3_-_71130892 0.72 ENST00000491238.7
ENST00000674446.1
forkhead box P1
chr9_+_113876282 0.71 ENST00000374126.9
ENST00000615615.4
ENST00000288466.11
zinc finger protein 618
chr5_+_162067500 0.71 ENST00000639384.1
ENST00000640985.1
ENST00000638772.1
gamma-aminobutyric acid type A receptor subunit gamma2
chr5_+_55160161 0.69 ENST00000296734.6
ENST00000515370.1
ENST00000503787.6
glutathione peroxidase 8 (putative)
chr21_+_29299368 0.67 ENST00000399921.5
BTB domain and CNC homolog 1
chr2_-_25982471 0.67 ENST00000264712.8
kinesin family member 3C
chr6_-_63319943 0.66 ENST00000622415.1
ENST00000370658.9
ENST00000485906.6
ENST00000370657.9
lengsin, lens protein with glutamine synthetase domain
chr9_-_91423819 0.64 ENST00000297689.4
nuclear factor, interleukin 3 regulated
chr4_+_1871373 0.63 ENST00000508803.6
ENST00000507820.5
ENST00000514045.5
nuclear receptor binding SET domain protein 2
chr14_+_85530127 0.62 ENST00000330753.6
fibronectin leucine rich transmembrane protein 2
chr6_+_55174508 0.62 ENST00000370862.4
hypocretin receptor 2
chr19_-_49361475 0.60 ENST00000598810.5
TEA domain transcription factor 2
chr15_-_101252040 0.60 ENST00000254190.4
chondroitin sulfate synthase 1
chr9_+_74615582 0.60 ENST00000396204.2
RAR related orphan receptor B
chr5_-_157575767 0.60 ENST00000257527.9
ADAM metallopeptidase domain 19
chr7_+_30852273 0.59 ENST00000509504.2
novel protein, MINDY4 and AQP1 readthrough
chr15_-_55917080 0.59 ENST00000506154.1
NEDD4 E3 ubiquitin protein ligase
chr10_+_112950757 0.59 ENST00000629706.2
ENST00000346198.5
transcription factor 7 like 2
chr7_+_130207847 0.59 ENST00000297819.4
serine rich single-pass membrane protein 1
chr5_-_65722094 0.59 ENST00000381007.9
small glutamine rich tetratricopeptide repeat containing beta
chr3_+_141386393 0.58 ENST00000503809.5
zinc finger and BTB domain containing 38
chr7_+_5592805 0.58 ENST00000382361.8
fascin actin-bundling protein 1
chr1_+_84181630 0.58 ENST00000610457.1
protein kinase cAMP-activated catalytic subunit beta
chr7_-_25228485 0.58 ENST00000222674.2
neuropeptide VF precursor
chr12_-_16606795 0.56 ENST00000447609.5
LIM domain only 3
chr3_+_39467598 0.56 ENST00000428261.5
ENST00000420739.5
ENST00000415443.5
ENST00000447324.5
ENST00000383754.7
myelin associated oligodendrocyte basic protein
chr5_+_172641241 0.56 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
neuralized E3 ubiquitin protein ligase 1B
chr5_+_31193678 0.56 ENST00000265071.3
cadherin 6
chrX_+_96684712 0.56 ENST00000373049.8
diaphanous related formin 2
chr12_+_32107296 0.55 ENST00000551086.1
BICD cargo adaptor 1
chr19_-_49362376 0.55 ENST00000601519.5
ENST00000593945.6
ENST00000539846.5
ENST00000596757.1
ENST00000311227.6
TEA domain transcription factor 2
chr2_+_11539833 0.55 ENST00000263834.9
growth regulating estrogen receptor binding 1
chr2_-_160200289 0.54 ENST00000409872.1
integrin subunit beta 6
chr2_-_72147819 0.54 ENST00000001146.7
ENST00000546307.5
ENST00000474509.1
cytochrome P450 family 26 subfamily B member 1
chr3_+_183265302 0.53 ENST00000465010.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr4_-_138242325 0.53 ENST00000280612.9
solute carrier family 7 member 11
chr9_+_125748175 0.53 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr16_-_1884231 0.53 ENST00000563416.3
ENST00000633813.1
ENST00000470044.5
long intergenic non-protein coding RNA 254
meiosis specific with OB-fold
chr16_-_46831043 0.52 ENST00000565112.1
chromosome 16 open reading frame 87
chr3_-_71581540 0.51 ENST00000650068.1
forkhead box P1
chrX_+_47078380 0.51 ENST00000352078.8
regucalcin
chr7_-_27180230 0.51 ENST00000396344.4
homeobox A10
chr14_+_75280078 0.50 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr17_-_41481140 0.50 ENST00000246639.6
ENST00000393989.1
keratin 35
chrX_+_47078330 0.50 ENST00000457380.5
regucalcin
chr5_+_31193739 0.50 ENST00000514738.5
cadherin 6
chr17_-_44947637 0.50 ENST00000587309.5
ENST00000593135.6
kinesin family member 18B
chr7_-_100100716 0.50 ENST00000354230.7
ENST00000425308.5
minichromosome maintenance complex component 7
chr12_+_53097656 0.50 ENST00000301464.4
insulin like growth factor binding protein 6
chr21_+_38256698 0.49 ENST00000613499.4
ENST00000612702.4
ENST00000398925.5
ENST00000398928.5
ENST00000328656.8
ENST00000443341.5
potassium inwardly rectifying channel subfamily J member 15
chr10_+_84452208 0.49 ENST00000480006.1
coiled-coil serine rich protein 2
chr2_-_160200251 0.49 ENST00000428609.6
ENST00000409967.6
ENST00000283249.7
integrin subunit beta 6
chrX_+_47078434 0.49 ENST00000397180.6
regucalcin
chr5_-_161546671 0.48 ENST00000517547.5
gamma-aminobutyric acid type A receptor subunit beta2
chr5_-_138338325 0.48 ENST00000510119.1
ENST00000513970.5
cell division cycle 25C
chr10_-_99620401 0.48 ENST00000370495.6
solute carrier family 25 member 28
chr5_+_162067764 0.48 ENST00000639213.2
ENST00000414552.6
gamma-aminobutyric acid type A receptor subunit gamma2
chr5_-_161546970 0.48 ENST00000675303.1
gamma-aminobutyric acid type A receptor subunit beta2
chr3_-_33645433 0.48 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr11_-_88175432 0.48 ENST00000531138.1
ENST00000526372.1
ENST00000243662.11
RAB38, member RAS oncogene family
chrX_-_100928903 0.47 ENST00000372956.3
XK related X-linked
chr10_+_112950586 0.47 ENST00000355717.9
ENST00000352065.10
ENST00000369395.6
ENST00000545257.6
transcription factor 7 like 2
chr2_-_160200310 0.47 ENST00000620391.4
integrin subunit beta 6
chr6_-_152983031 0.47 ENST00000229758.8
F-box protein 5
chr18_+_44697118 0.47 ENST00000677077.1
SET binding protein 1
chr5_+_162067458 0.47 ENST00000639975.1
ENST00000639111.2
ENST00000639683.1
gamma-aminobutyric acid type A receptor subunit gamma2
chr3_-_142028597 0.46 ENST00000467667.5
transcription factor Dp-2
chr6_-_25874212 0.46 ENST00000361703.10
ENST00000397060.8
solute carrier family 17 member 3
chr13_+_29428603 0.46 ENST00000380808.6
microtubule associated scaffold protein 2
chr2_-_215393126 0.46 ENST00000456923.5
fibronectin 1
chr10_-_67838173 0.45 ENST00000225171.7
DnaJ heat shock protein family (Hsp40) member C12
chr7_+_74289397 0.45 ENST00000223398.11
ENST00000361545.9
CAP-Gly domain containing linker protein 2
chr14_+_60734727 0.45 ENST00000261245.9
ENST00000539616.6
MNAT1 component of CDK activating kinase
chr21_-_30813270 0.44 ENST00000329621.6
keratin associated protein 8-1
chr7_-_19773569 0.44 ENST00000422233.5
ENST00000433641.5
ENST00000405844.6
transmembrane protein 196
chr11_-_41459592 0.44 ENST00000528697.6
ENST00000530763.5
leucine rich repeat containing 4C
chr10_-_114404480 0.43 ENST00000419268.1
ENST00000304129.9
actin filament associated protein 1 like 2
chr3_-_71064915 0.43 ENST00000614176.5
ENST00000485326.7
forkhead box P1
chr10_-_114404756 0.43 ENST00000369271.7
actin filament associated protein 1 like 2
chr2_+_96325294 0.43 ENST00000439118.3
ENST00000420176.5
ENST00000536814.1
ITPRIP like 1
chr11_-_57530714 0.43 ENST00000525158.1
ENST00000257245.9
ENST00000525587.1
translocase of inner mitochondrial membrane 10
chr17_+_82458174 0.43 ENST00000579198.5
ENST00000390006.8
ENST00000580296.5
nuclear prelamin A recognition factor
chr13_-_23433676 0.43 ENST00000682547.1
ENST00000455470.6
ENST00000382292.9
sacsin molecular chaperone
chr1_-_53838276 0.43 ENST00000371429.4
NDC1 transmembrane nucleoporin
chr3_-_71064964 0.43 ENST00000650387.1
forkhead box P1
chr8_+_62248933 0.42 ENST00000523211.5
ENST00000524201.1
sodium/potassium transporting ATPase interacting 3
chr18_-_48950960 0.42 ENST00000262158.8
SMAD family member 7
chrX_+_96684801 0.42 ENST00000324765.13
diaphanous related formin 2
chr5_+_3595820 0.42 ENST00000302006.4
iroquois homeobox 1
chr12_+_1629197 0.42 ENST00000397196.7
Wnt family member 5B
chr21_+_38256984 0.41 ENST00000398938.7
potassium inwardly rectifying channel subfamily J member 15
chr4_+_94207596 0.41 ENST00000359052.8
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr17_+_82458649 0.41 ENST00000345415.11
ENST00000412079.6
ENST00000457415.7
ENST00000584411.5
ENST00000577432.5
nuclear prelamin A recognition factor
chr14_-_34713759 0.41 ENST00000673315.1
cofilin 2
chr16_-_9943182 0.40 ENST00000535259.6
glutamate ionotropic receptor NMDA type subunit 2A
chr6_-_152983561 0.40 ENST00000367241.3
F-box protein 5
chr15_-_70096604 0.40 ENST00000559048.5
ENST00000560939.5
ENST00000440567.7
ENST00000557907.5
ENST00000558379.5
ENST00000559929.5
TLE family member 3, transcriptional corepressor
chr7_-_29195186 0.40 ENST00000449801.5
ENST00000409850.5
carboxypeptidase vitellogenic like
chr2_+_27442365 0.40 ENST00000543753.5
ENST00000288873.7
keratinocyte associated protein 3
chr15_-_55917129 0.39 ENST00000338963.6
ENST00000508342.5
NEDD4 E3 ubiquitin protein ligase
chr11_+_112961480 0.39 ENST00000621850.4
neural cell adhesion molecule 1
chr15_-_70096260 0.39 ENST00000558201.5
TLE family member 3, transcriptional corepressor
chr1_+_84164684 0.39 ENST00000370680.5
protein kinase cAMP-activated catalytic subunit beta
chr12_-_16608183 0.39 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr11_-_66677748 0.39 ENST00000525754.5
ENST00000531969.5
ENST00000524637.1
ENST00000531036.2
ENST00000310046.9
RNA binding motif protein 4B
chr11_+_112961402 0.39 ENST00000613217.4
ENST00000316851.12
ENST00000620046.4
ENST00000531044.5
ENST00000529356.5
neural cell adhesion molecule 1
chr10_-_17129786 0.39 ENST00000377833.10
cubilin
chr14_-_23578756 0.38 ENST00000397118.7
ENST00000356300.9
junctophilin 4
chr1_+_93079234 0.38 ENST00000540243.5
ENST00000545708.5
metal response element binding transcription factor 2
chr12_-_16608073 0.38 ENST00000441439.6
LIM domain only 3
chr7_+_73830988 0.38 ENST00000340958.4
claudin 4
chr1_-_153113507 0.38 ENST00000468739.2
small proline rich protein 2F
chr14_+_85530163 0.38 ENST00000554746.1
fibronectin leucine rich transmembrane protein 2
chrX_+_54809060 0.37 ENST00000396224.1
MAGE family member D2
chr12_+_54561442 0.37 ENST00000550620.1
phosphodiesterase 1B
chr2_+_170715317 0.37 ENST00000375281.4
Sp5 transcription factor
chr5_+_171419635 0.37 ENST00000274625.6
fibroblast growth factor 18
chr2_+_27442421 0.37 ENST00000407293.5
keratinocyte associated protein 3
chr13_-_23433735 0.37 ENST00000423156.2
ENST00000683210.1
ENST00000682775.1
ENST00000684497.1
ENST00000682944.1
ENST00000683489.1
ENST00000684385.1
ENST00000683680.1
sacsin molecular chaperone
chr6_+_113857333 0.36 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr16_-_22374580 0.36 ENST00000268383.7
cerebellar degeneration related protein 2
chr1_-_156572535 0.36 ENST00000361170.7
IQ motif containing GTPase activating protein 3
chr14_-_80959484 0.36 ENST00000555529.5
ENST00000556042.5
ENST00000556981.5
centrosomal protein 128
chrX_-_43973382 0.35 ENST00000642620.1
ENST00000647044.1
norrin cystine knot growth factor NDP
chr19_+_751104 0.35 ENST00000215582.8
mitotic spindle positioning
chr9_+_100427254 0.35 ENST00000374885.5
Myb/SANT DNA binding domain containing 3
chr4_+_153466324 0.34 ENST00000409663.7
ENST00000409959.8
transmembrane 131 like
chr5_+_161848536 0.34 ENST00000519621.2
ENST00000636573.1
gamma-aminobutyric acid type A receptor subunit alpha1
chr18_-_26865732 0.34 ENST00000672188.1
aquaporin 4
chr11_+_5389377 0.34 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chrX_+_96684638 0.34 ENST00000355827.8
ENST00000373061.7
diaphanous related formin 2
chr4_+_94207845 0.34 ENST00000457823.6
ENST00000354268.9
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr17_-_41055211 0.34 ENST00000542910.1
ENST00000398477.1
keratin associated protein 2-2
chr2_+_203867943 0.33 ENST00000295854.10
ENST00000487393.1
ENST00000472206.1
cytotoxic T-lymphocyte associated protein 4
chrX_+_96684929 0.33 ENST00000373054.5
diaphanous related formin 2
chr12_-_31324129 0.33 ENST00000454658.6
SIN3-HDAC complex associated factor
chr1_+_47333863 0.33 ENST00000471289.2
ENST00000450808.2
cytidine/uridine monophosphate kinase 1
chr6_+_20403679 0.33 ENST00000535432.2
E2F transcription factor 3
chr8_-_17002327 0.33 ENST00000180166.6
fibroblast growth factor 20
chr12_+_103965835 0.33 ENST00000266775.13
ENST00000544861.5
thymine DNA glycosylase
chr12_-_117968972 0.32 ENST00000339824.7
kinase suppressor of ras 2
chrX_-_81201886 0.32 ENST00000451455.1
ENST00000358130.7
ENST00000436386.5
high mobility group nucleosome binding domain 5
chr8_-_132760548 0.32 ENST00000519187.5
ENST00000523829.5
ENST00000677595.1
ENST00000356838.7
ENST00000377901.8
ENST00000519304.1
transmembrane protein 71
chr2_-_165203870 0.32 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
sodium voltage-gated channel alpha subunit 3
chr3_-_147406520 0.32 ENST00000463250.1
ENST00000383075.8
Zic family member 4
chr3_+_107525378 0.32 ENST00000456419.5
ENST00000402163.6
BBX high mobility group box domain containing
chr2_-_169362527 0.32 ENST00000649046.1
ENST00000443831.1
LDL receptor related protein 2
chr17_+_77451244 0.32 ENST00000591088.5
septin 9
chr12_+_103965798 0.32 ENST00000436021.6
thymine DNA glycosylase
chr13_-_27969295 0.32 ENST00000381020.8
caudal type homeobox 2
chr11_-_57427474 0.32 ENST00000533235.5
ENST00000526621.5
ENST00000352187.5
solute carrier family 43 member 3
chr18_-_26865689 0.32 ENST00000675739.1
ENST00000383168.9
ENST00000672981.2
ENST00000578776.1
aquaporin 4
chr7_+_69599588 0.31 ENST00000403018.3
activator of transcription and developmental regulator AUTS2
chr3_-_149086488 0.31 ENST00000392912.6
ENST00000465259.5
ENST00000310053.10
ENST00000494055.5
helicase like transcription factor
chr6_+_37170133 0.31 ENST00000373509.6
Pim-1 proto-oncogene, serine/threonine kinase
chr7_+_80646305 0.31 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr11_+_112961247 0.31 ENST00000621518.4
ENST00000618266.4
ENST00000615112.4
ENST00000615285.4
ENST00000619839.4
ENST00000401611.6
ENST00000621128.4
neural cell adhesion molecule 1
chr13_+_75636311 0.31 ENST00000377499.9
ENST00000377534.8
LIM domain 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.4 1.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.4 1.5 GO:1903611 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.3 1.0 GO:0019089 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.3 5.5 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.3 0.9 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.3 0.8 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.3 0.8 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.2 0.9 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.2 0.7 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 5.5 GO:0071420 cellular response to histamine(GO:0071420)
0.2 0.6 GO:1990009 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.2 1.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 2.0 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 0.5 GO:0097086 amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
0.2 2.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.2 0.7 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 1.2 GO:0097338 response to clozapine(GO:0097338)
0.2 0.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 0.5 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.2 0.6 GO:0003290 atrial septum secundum morphogenesis(GO:0003290)
0.2 2.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.2 1.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 0.9 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 0.5 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 3.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 0.4 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.5 GO:0030576 Cajal body organization(GO:0030576)
0.1 1.8 GO:0015816 glycine transport(GO:0015816)
0.1 1.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.7 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 0.5 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.1 1.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 0.3 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.9 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.3 GO:0048867 stem cell fate determination(GO:0048867)
0.1 0.6 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.8 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.3 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 0.6 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.1 0.2 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.1 0.4 GO:0033058 directional locomotion(GO:0033058)
0.1 0.7 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.2 GO:0003358 noradrenergic neuron development(GO:0003358)
0.1 0.5 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.4 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 0.3 GO:0032600 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.1 0.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.3 GO:0019418 succinate transport(GO:0015744) sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221) succinate transmembrane transport(GO:0071422)
0.1 0.1 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 0.9 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.1 GO:0042662 negative regulation of mesodermal cell fate specification(GO:0042662)
0.1 0.5 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.6 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.7 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) renal water absorption(GO:0070295)
0.1 0.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.2 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.4 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 2.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.3 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 0.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.5 GO:0097491 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1 0.3 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.5 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0007144 female meiosis I(GO:0007144)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.7 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.3 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 1.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.8 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.3 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.7 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.2 GO:1904782 negative regulation of glutamate receptor signaling pathway(GO:1900450) negative regulation of NMDA glutamate receptor activity(GO:1904782) positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.0 0.2 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:0050904 diapedesis(GO:0050904)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.3 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.2 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.0 0.3 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415) negative regulation of histone H3-K4 methylation(GO:0051572)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.2 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.5 GO:0007512 adult heart development(GO:0007512)
0.0 0.7 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.3 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.2 GO:0007412 axon target recognition(GO:0007412)
0.0 0.4 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.7 GO:0060065 uterus development(GO:0060065)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 4.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.0 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.7 GO:0006833 water transport(GO:0006833)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.2 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:2000174 pro-T cell differentiation(GO:0002572) regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.6 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0060309 elastin catabolic process(GO:0060309)
0.0 0.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.3 GO:0060346 bone trabecula formation(GO:0060346)
0.0 0.0 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.1 GO:0048619 hindgut morphogenesis(GO:0007442) embryonic hindgut morphogenesis(GO:0048619)
0.0 0.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 2.0 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.0 0.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.3 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 1.1 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.4 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.9 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.5 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 1.0 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.0 0.7 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.0 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.2 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.0 GO:0021658 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:1905049 negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0 0.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 1.4 GO:0048477 oogenesis(GO:0048477)
0.0 2.0 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.0 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.1 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 1.5 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 1.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 2.5 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.2 2.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.6 GO:0044393 microspike(GO:0044393)
0.1 1.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.5 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 5.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 1.9 GO:0045120 pronucleus(GO:0045120)
0.1 0.4 GO:0039713 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 0.5 GO:0031905 early endosome lumen(GO:0031905)
0.1 2.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.9 GO:0005638 lamin filament(GO:0005638)
0.1 0.8 GO:0070852 cell body fiber(GO:0070852)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.6 GO:0045180 basal cortex(GO:0045180)
0.1 0.4 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 4.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.4 GO:0005816 spindle pole body(GO:0005816)
0.0 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 1.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 1.2 GO:0031143 pseudopodium(GO:0031143)
0.0 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.5 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.9 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0070761 PCAF complex(GO:0000125) pre-snoRNP complex(GO:0070761)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.5 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.4 1.5 GO:0004341 gluconolactonase activity(GO:0004341)
0.3 1.7 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.3 1.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.3 0.9 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2 1.0 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 4.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.2 0.5 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 0.5 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 0.5 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 0.7 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 1.8 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.6 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 1.9 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.0 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.9 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.4 GO:0002046 opsin binding(GO:0002046)
0.1 1.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 0.5 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.9 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 2.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.8 GO:1904315 GABA-gated chloride ion channel activity(GO:0022851) neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.4 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 1.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.8 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 4.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 5.8 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 1.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.5 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.0 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0015250 water channel activity(GO:0015250)
0.0 4.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.6 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.5 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.8 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 1.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.0 GO:0031691 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130) neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 1.0 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 2.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 2.5 PID E2F PATHWAY E2F transcription factor network
0.0 2.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 4.1 REACTOME KINESINS Genes involved in Kinesins
0.0 0.9 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 2.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 2.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.1 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.7 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.0 0.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates