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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for LHX2

Z-value: 0.56

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Transcription factors associated with LHX2

Gene Symbol Gene ID Gene Info
LHX2
ENSG00000106689.11 LHX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX2hg38_v1_chr9_+_124015397_124015421,
hg38_v1_chr9_+_124011738_124011777		0.402.8e-02Click!

Activity profile of LHX2 motif

Sorted Z-values of LHX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_35938572 7.05 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
CAPSL
calcyphosine like
chr12_-_25195074 3.70 ENST00000354189.9
ENST00000676236.1
ENST00000545133.5
ENST00000554347.1
ENST00000674567.1
ENST00000395987.8
ENST00000320267.13
ENST00000395990.6
CFAP94
cilia and flagella associated protein 94
chr20_+_33283205 3.66 ENST00000253354.2
BPIFB1
BPI fold containing family B member 1
chr6_+_112087576 2.73 ENST00000368656.7
ENST00000604268.1
FAM229B
family with sequence similarity 229 member B
chr9_-_135499846 2.05 ENST00000429260.7
C9orf116
chromosome 9 open reading frame 116
chr11_+_27055215 1.79 ENST00000525090.1
BBOX1
gamma-butyrobetaine hydroxylase 1
chr13_+_24270681 1.70 ENST00000343003.10
ENST00000399949.6
SPATA13
spermatogenesis associated 13
chr10_-_104232301 1.62 ENST00000369720.6
ENST00000369719.2
ENST00000278064.7
ENST00000357060.8
CFAP43
cilia and flagella associated protein 43
chr5_+_141223332 1.62 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
PCDHB14
ENSG00000279983.1
protocadherin beta 14
novel protein
chr4_+_15469865 1.49 ENST00000515124.6
ENST00000512702.6
ENST00000503292.6
ENST00000424120.6
ENST00000507954.5
ENST00000514450.3
ENST00000503658.2
CC2D2A
coiled-coil and C2 domain containing 2A
chr7_-_137343752 1.45 ENST00000393083.2
PTN
pleiotrophin
chr18_+_63702958 1.23 ENST00000544088.6
SERPINB11
serpin family B member 11
chr7_-_137343688 1.19 ENST00000348225.7
PTN
pleiotrophin
chr8_+_75539893 1.08 ENST00000674002.1
HNF4G
hepatocyte nuclear factor 4 gamma
chr7_+_37920602 1.06 ENST00000199448.9
ENST00000423717.1
EPDR1
ependymin related 1
chr11_+_124183219 1.04 ENST00000641351.2
OR10D3
olfactory receptor family 10 subfamily D member 3
chr8_+_75539862 1.02 ENST00000396423.4
HNF4G
hepatocyte nuclear factor 4 gamma
chr1_-_150765785 1.01 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
CTSS
cathepsin S
chr2_-_177618705 0.96 ENST00000355689.6
TTC30A
tetratricopeptide repeat domain 30A
chr10_+_70404129 0.71 ENST00000373218.5
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr3_+_93980203 0.68 ENST00000679607.1
ENST00000679587.1
ARL13B
ADP ribosylation factor like GTPase 13B
chr18_+_58341038 0.67 ENST00000679791.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr11_+_36594369 0.67 ENST00000678060.1
ENST00000446510.6
ENST00000676979.1
ENST00000677808.1
ENST00000617650.5
ENST00000334307.10
ENST00000531554.6
ENST00000679022.1
ENST00000347206.8
ENST00000534635.5
ENST00000676921.1
ENST00000678950.1
ENST00000530697.6
ENST00000527108.6
ENST00000532470.3
IFTAP
intraflagellar transport associated protein
chr5_+_36606355 0.62 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
SLC1A3
solute carrier family 1 member 3
chr1_-_183590876 0.62 ENST00000367536.5
NCF2
neutrophil cytosolic factor 2
chr14_-_89412025 0.61 ENST00000553840.5
ENST00000556916.5
FOXN3
forkhead box N3
chr6_+_32844789 0.59 ENST00000414474.5
PSMB9
proteasome 20S subunit beta 9
chr10_-_114526897 0.59 ENST00000428430.1
ENST00000392952.7
ABLIM1
actin binding LIM protein 1
chr6_-_75363003 0.56 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr2_-_10447771 0.55 ENST00000405333.5
ENST00000443218.1
ODC1
ornithine decarboxylase 1
chr1_+_210328244 0.54 ENST00000541565.5
ENST00000413764.6
HHAT
hedgehog acyltransferase
chr11_+_124184244 0.52 ENST00000641546.1
OR10D3
olfactory receptor family 10 subfamily D member 3
chr3_+_108822778 0.51 ENST00000295756.11
TRAT1
T cell receptor associated transmembrane adaptor 1
chr14_+_22226711 0.49 ENST00000390463.3
TRAV36DV7
T cell receptor alpha variable 36/delta variable 7
chr7_-_5959083 0.46 ENST00000539903.5
RSPH10B
radial spoke head 10 homolog B
chr1_-_115089414 0.44 ENST00000433172.3
ENST00000369515.6
ENST00000369516.7
TSPAN2
tetraspanin 2
chr3_+_108822759 0.43 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr5_+_69565122 0.43 ENST00000507595.1
GTF2H2C
GTF2H2 family member C
chr17_+_59331633 0.41 ENST00000312655.9
YPEL2
yippee like 2
chr2_-_174847765 0.41 ENST00000443238.6
CHN1
chimerin 1
chr2_+_119679184 0.41 ENST00000445518.1
ENST00000272521.7
ENST00000409951.1
TMEM177
transmembrane protein 177
chr2_+_119679154 0.40 ENST00000401466.5
ENST00000424086.5
TMEM177
transmembrane protein 177
chr10_-_60141004 0.40 ENST00000355288.6
ANK3
ankyrin 3
chr14_+_55611977 0.37 ENST00000395309.7
ENST00000413890.6
KTN1
kinectin 1
chr11_+_92969651 0.37 ENST00000257068.3
ENST00000528076.1
MTNR1B
melatonin receptor 1B
chr6_-_26027274 0.35 ENST00000377745.4
H4C2
H4 clustered histone 2
chrX_+_11111291 0.35 ENST00000321143.8
ENST00000380762.5
ENST00000380763.7
HCCS
holocytochrome c synthase
chr2_-_174847525 0.35 ENST00000295497.12
ENST00000652036.1
ENST00000444394.6
ENST00000650731.1
CHN1
chimerin 1
chrM_+_12329 0.34 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
chr7_+_100119607 0.32 ENST00000262932.5
CNPY4
canopy FGF signaling regulator 4
chr5_-_75712419 0.31 ENST00000510798.5
ENST00000446329.6
POC5
POC5 centriolar protein
chr17_+_46923075 0.31 ENST00000640608.1
ENST00000638634.1
ENST00000623037.2
ENST00000225567.9
ENST00000415811.7
ENST00000576910.7
ENST00000573224.2
ENST00000640621.1
ENST00000638892.1
ENST00000638838.1
ENST00000638216.1
ENST00000575949.6
ENST00000640806.1
ENST00000640269.1
ENST00000640443.1
ENST00000638697.1
ENST00000640051.2
ENST00000640007.1
ENST00000640711.1
ENST00000640495.1
ENST00000638374.1
ENST00000571048.1
ENST00000639287.1
ENST00000640138.1
ENST00000570879.2
ENST00000640068.1
ENST00000393456.7
ENST00000639031.1
GOSR2
golgi SNAP receptor complex member 2
chr19_+_55857437 0.28 ENST00000587891.5
NLRP4
NLR family pyrin domain containing 4
chr3_+_138621207 0.28 ENST00000464668.5
FAIM
Fas apoptotic inhibitory molecule
chr10_+_68106109 0.27 ENST00000540630.5
ENST00000354393.6
MYPN
myopalladin
chr8_-_81483226 0.27 ENST00000256104.5
FABP4
fatty acid binding protein 4
chr3_+_119468952 0.26 ENST00000476573.5
ENST00000295588.9
POGLUT1
protein O-glucosyltransferase 1
chr3_-_191282383 0.26 ENST00000427544.6
UTS2B
urotensin 2B
chr13_+_76948500 0.25 ENST00000377462.6
ACOD1
aconitate decarboxylase 1
chr3_+_4680617 0.25 ENST00000648212.1
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chr12_-_100262356 0.24 ENST00000548313.5
DEPDC4
DEP domain containing 4
chr13_-_109786567 0.24 ENST00000375856.5
IRS2
insulin receptor substrate 2
chr6_+_29306626 0.23 ENST00000377160.4
OR14J1
olfactory receptor family 14 subfamily J member 1
chr1_+_160400543 0.23 ENST00000368061.3
VANGL2
VANGL planar cell polarity protein 2
chr5_-_151093566 0.22 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr16_+_86566821 0.21 ENST00000649859.1
FOXC2
forkhead box C2
chr1_+_182450132 0.21 ENST00000294854.13
RGSL1
regulator of G protein signaling like 1
chr1_-_89126066 0.21 ENST00000370466.4
GBP2
guanylate binding protein 2
chr7_+_101817601 0.21 ENST00000292535.12
ENST00000546411.7
ENST00000549414.6
ENST00000550008.6
ENST00000556210.1
CUX1
cut like homeobox 1
chr13_+_73058993 0.20 ENST00000377687.6
KLF5
Kruppel like factor 5
chr7_-_38265678 0.20 ENST00000443402.6
TRGC1
T cell receptor gamma constant 1
chr3_+_138621225 0.20 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr5_+_141412979 0.20 ENST00000612503.1
ENST00000398610.3
PCDHGA10
protocadherin gamma subfamily A, 10
chr11_-_4608226 0.19 ENST00000300747.10
ENST00000526337.5
TRIM68
tripartite motif containing 68
chr17_-_41140487 0.18 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr17_+_50746614 0.18 ENST00000513969.5
ENST00000503728.1
LUC7L3
LUC7 like 3 pre-mRNA splicing factor
chr20_+_5750437 0.18 ENST00000445603.1
ENST00000442185.1
SHLD1
shieldin complex subunit 1
chr20_+_44401222 0.17 ENST00000316099.9
HNF4A
hepatocyte nuclear factor 4 alpha
chr12_-_21775581 0.17 ENST00000537950.1
ENST00000665145.1
KCNJ8
potassium inwardly rectifying channel subfamily J member 8
chr14_+_69398683 0.16 ENST00000556605.5
ENST00000031146.8
ENST00000336643.10
SLC39A9
solute carrier family 39 member 9
chrX_-_77634229 0.16 ENST00000675732.1
ATRX
ATRX chromatin remodeler
chr13_-_99258366 0.15 ENST00000397470.5
ENST00000397473.7
GPR18
G protein-coupled receptor 18
chr1_+_248508073 0.15 ENST00000641804.1
OR2G6
olfactory receptor family 2 subfamily G member 6
chr9_-_21202205 0.15 ENST00000239347.3
IFNA7
interferon alpha 7
chr3_-_161105070 0.15 ENST00000651430.1
ENST00000650695.1
ENST00000651689.1
ENST00000651916.1
ENST00000488170.5
ENST00000652377.1
ENST00000652669.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_+_160739239 0.14 ENST00000368043.8
SLAMF7
SLAM family member 7
chr9_+_111896804 0.14 ENST00000374279.4
UGCG
UDP-glucose ceramide glucosyltransferase
chr16_+_283157 0.14 ENST00000219406.11
ENST00000404312.5
ENST00000456379.1
PDIA2
protein disulfide isomerase family A member 2
chr4_+_48483324 0.14 ENST00000273861.5
SLC10A4
solute carrier family 10 member 4
chr5_-_24644968 0.14 ENST00000264463.8
CDH10
cadherin 10
chr11_-_40294089 0.13 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr1_-_205121964 0.13 ENST00000264515.11
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit
chr11_-_108222594 0.13 ENST00000278612.9
NPAT
nuclear protein, coactivator of histone transcription
chr3_-_161105224 0.12 ENST00000651254.1
ENST00000651178.1
ENST00000476999.6
ENST00000652596.1
ENST00000651305.1
ENST00000652111.1
ENST00000651292.1
ENST00000651282.1
ENST00000651380.1
ENST00000494173.7
ENST00000484127.5
ENST00000650733.1
ENST00000494818.6
ENST00000492353.5
ENST00000652143.1
ENST00000473142.5
ENST00000651147.1
ENST00000468268.5
ENST00000460353.2
ENST00000651953.1
ENST00000651972.1
ENST00000652730.1
ENST00000651460.1
ENST00000652059.1
ENST00000651509.1
ENST00000651801.1
ENST00000651686.1
ENST00000320474.10
ENST00000392781.7
ENST00000392779.6
ENST00000651791.1
ENST00000651117.1
ENST00000652032.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr3_+_98147479 0.12 ENST00000641380.1
OR5H14
olfactory receptor family 5 subfamily H member 14
chr11_+_55635113 0.12 ENST00000641760.1
OR4P4
olfactory receptor family 4 subfamily P member 4
chr3_-_12545499 0.12 ENST00000564146.4
MKRN2OS
MKRN2 opposite strand
chr11_-_125111708 0.12 ENST00000531909.5
ENST00000529530.1
TMEM218
transmembrane protein 218
chr1_+_160739265 0.12 ENST00000368042.7
SLAMF7
SLAM family member 7
chr12_-_91179472 0.12 ENST00000550099.5
ENST00000546391.5
DCN
decorin
chr2_+_68974573 0.12 ENST00000673932.3
ENST00000377938.4
GKN1
gastrokine 1
chr18_+_62539511 0.11 ENST00000586834.1
ZCCHC2
zinc finger CCHC-type containing 2
chr2_-_230219902 0.11 ENST00000409815.6
SP110
SP110 nuclear body protein
chr5_-_59216826 0.11 ENST00000638939.1
PDE4D
phosphodiesterase 4D
chr12_-_91111460 0.11 ENST00000266718.5
LUM
lumican
chr1_+_160739286 0.10 ENST00000359331.8
ENST00000495334.1
SLAMF7
SLAM family member 7
chr14_-_69398276 0.10 ENST00000557016.6
ENST00000555373.1
ERH
ERH mRNA splicing and mitosis factor
chr3_-_161105399 0.09 ENST00000652593.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr7_-_100119840 0.09 ENST00000437822.6
TAF6
TATA-box binding protein associated factor 6
chr7_-_83649097 0.09 ENST00000643230.2
SEMA3E
semaphorin 3E
chr20_+_35954564 0.08 ENST00000622112.4
ENST00000614708.1
CNBD2
cyclic nucleotide binding domain containing 2
chr2_-_127526444 0.08 ENST00000295321.9
IWS1
interacts with SUPT6H, CTD assembly factor 1
chr15_-_72271244 0.08 ENST00000287196.13
PARP6
poly(ADP-ribose) polymerase family member 6
chrX_+_76173010 0.08 ENST00000373357.3
ENST00000373358.8
PBDC1
polysaccharide biosynthesis domain containing 1
chr12_+_93677352 0.07 ENST00000552983.5
ENST00000332896.8
ENST00000552033.5
ENST00000548483.5
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr2_+_108588453 0.07 ENST00000393310.5
LIMS1
LIM zinc finger domain containing 1
chr14_+_22105305 0.07 ENST00000390453.1
TRAV24
T cell receptor alpha variable 24
chr17_+_59940908 0.07 ENST00000591035.1
ENSG00000267318.1
novel protein
chr12_-_118359105 0.07 ENST00000541186.5
ENST00000539872.5
TAOK3
TAO kinase 3
chr8_+_28891304 0.07 ENST00000355231.9
HMBOX1
homeobox containing 1
chr1_-_246193727 0.06 ENST00000391836.3
SMYD3
SET and MYND domain containing 3
chr11_-_47642519 0.06 ENST00000302503.8
ENST00000530428.1
MTCH2
mitochondrial carrier 2
chr1_-_153922901 0.05 ENST00000634401.1
ENST00000368655.5
GATAD2B
GATA zinc finger domain containing 2B
chr1_-_7940825 0.05 ENST00000377507.8
TNFRSF9
TNF receptor superfamily member 9
chr3_-_131502946 0.05 ENST00000512877.1
ENST00000264995.8
ENST00000511168.5
ENST00000425847.6
MRPL3
mitochondrial ribosomal protein L3
chr12_-_10998304 0.05 ENST00000538986.2
TAS2R20
taste 2 receptor member 20
chrX_-_15314543 0.04 ENST00000344384.8
ASB11
ankyrin repeat and SOCS box containing 11
chr14_-_50561119 0.04 ENST00000555216.5
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr18_-_47176297 0.03 ENST00000639845.1
ENST00000256433.6
IER3IP1
immediate early response 3 interacting protein 1
chr1_+_99646025 0.03 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
PALMD
palmdelphin
chr20_+_58888779 0.03 ENST00000488546.6
ENST00000667293.2
ENST00000481039.6
ENST00000467321.6
GNAS
GNAS complex locus
chr10_+_122560639 0.03 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
DMBT1
deleted in malignant brain tumors 1
chr21_-_14210884 0.02 ENST00000679868.1
ENST00000400211.3
ENST00000680801.1
ENST00000536861.6
ENST00000614229.5
LIPI
lipase I
chrY_+_18546691 0.02 ENST00000309834.8
ENST00000307393.3
ENST00000382856.2
HSFY1
heat shock transcription factor Y-linked 1
chr8_+_91070196 0.02 ENST00000617869.4
ENST00000615618.1
ENST00000285420.8
ENST00000404789.8
OTUD6B
OTU deubiquitinase 6B
chr11_+_94973640 0.02 ENST00000335080.6
ENST00000536741.1
KDM4D
lysine demethylase 4D
chr16_-_56451316 0.02 ENST00000300291.10
NUDT21
nudix hydrolase 21
chr5_+_168486462 0.02 ENST00000231572.8
ENST00000626454.1
RARS1
arginyl-tRNA synthetase 1
chr1_+_192716132 0.02 ENST00000647225.1
ENST00000443181.2
RPS27AP5
ribosomal protein S27a pseudogene 5
chr16_+_56451513 0.01 ENST00000562150.5
ENST00000561646.5
ENST00000566157.6
ENST00000568397.1
OGFOD1
2-oxoglutarate and iron dependent oxygenase domain containing 1
chr9_-_113299196 0.01 ENST00000441031.3
RNF183
ring finger protein 183
chr3_+_37975773 0.01 ENST00000436654.1
CTDSPL
CTD small phosphatase like
chr7_+_156640879 0.01 ENST00000311822.12
RNF32
ring finger protein 32
chr7_-_81770122 0.01 ENST00000423064.7
HGF
hepatocyte growth factor
chr1_-_207032749 0.01 ENST00000359470.6
ENST00000461135.2
C1orf116
chromosome 1 open reading frame 116

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.3 1.0 GO:0034769 basement membrane disassembly(GO:0034769)
0.3 1.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 3.7 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.2 1.8 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.5 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.4 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.4 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 0.2 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.2 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.1 0.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.6 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.7 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.1 0.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.2 GO:1904907 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.1 0.2 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.2 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 1.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.6 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 2.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.6 GO:0045730 respiratory burst(GO:0045730)
0.0 0.6 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 1.0 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 0.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.6 GO:0032010 phagolysosome(GO:0032010)
0.1 1.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.0 1.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.9 GO:0042101 T cell receptor complex(GO:0042101)
0.0 3.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.6 1.8 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.4 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 2.0 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.5 GO:0016409 palmitoyltransferase activity(GO:0016409)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 2.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.9 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation