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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for LHX6

Z-value: 0.59

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Transcription factors associated with LHX6

Gene Symbol Gene ID Gene Info
ENSG00000106852.15 LHX6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX6hg38_v1_chr9_-_122228845_122228967,
hg38_v1_chr9_-_122227525_122227586
0.125.4e-01Click!

Activity profile of LHX6 motif

Sorted Z-values of LHX6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_35938572 3.95 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
calcyphosine like
chr12_+_6904733 3.61 ENST00000007969.12
ENST00000622489.4
ENST00000443597.7
ENST00000323702.9
leucine rich repeat containing 23
chr12_+_6904962 2.79 ENST00000415834.5
ENST00000436789.5
leucine rich repeat containing 23
chr21_-_42496186 2.61 ENST00000398352.3
ENST00000291536.8
radial spoke head component 1
chr4_-_7042931 2.45 ENST00000310085.6
coiled-coil domain containing 96
chr3_-_180679468 2.38 ENST00000651046.1
ENST00000476379.6
coiled-coil domain containing 39
chr17_-_1628808 2.31 ENST00000301335.10
solute carrier family 43 member 2
chr1_-_36440873 2.01 ENST00000433045.6
organic solute carrier partner 1
chr4_+_164754045 1.99 ENST00000515485.5
small integral membrane protein 31
chr10_-_121515179 1.96 ENST00000429361.5
fibroblast growth factor receptor 2
chr4_+_164754116 1.48 ENST00000507311.1
small integral membrane protein 31
chr4_+_94974984 1.40 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr6_-_46170939 1.33 ENST00000230565.3
ENST00000371383.7
ectonucleotide pyrophosphatase/phosphodiesterase family member 5
chr18_+_46946821 1.32 ENST00000245121.9
ENST00000356157.12
katanin catalytic subunit A1 like 2
chr6_-_166627244 1.25 ENST00000265678.9
ribosomal protein S6 kinase A2
chr13_+_36431898 1.18 ENST00000440264.5
cyclin A1
chrX_-_152830721 1.18 ENST00000370277.5
centrin 2
chr3_-_129428590 1.16 ENST00000503957.1
ENST00000505956.6
ENST00000326085.7
EF-hand calcium binding domain 12
chr13_+_36432487 1.09 ENST00000255465.7
ENST00000625767.1
cyclin A1
chr9_+_1050330 1.03 ENST00000382255.7
ENST00000382251.7
ENST00000412350.6
ENST00000358146.7
doublesex and mab-3 related transcription factor 2
chr17_-_75941035 0.95 ENST00000586717.5
Fas binding factor 1
chr15_+_40405787 0.95 ENST00000610693.5
ENST00000479013.7
ENST00000487418.8
isovaleryl-CoA dehydrogenase
chr17_-_1628341 0.94 ENST00000571650.5
solute carrier family 43 member 2
chr3_-_112975018 0.91 ENST00000471858.5
ENST00000308611.8
ENST00000295863.4
CD200 receptor 1
chr10_-_45672708 0.91 ENST00000374366.7
ENST00000374371.6
ENST00000344646.10
zinc finger AN1-type containing 4
chr12_-_101739426 0.87 ENST00000266743.6
ENST00000392924.2
ENST00000392927.7
synaptonemal complex protein 3
chr22_-_38794111 0.83 ENST00000406622.5
ENST00000216068.9
ENST00000406199.3
Sad1 and UNC84 domain containing 2
dynein axonemal light chain 4
chr7_+_71132123 0.81 ENST00000333538.10
polypeptide N-acetylgalactosaminyltransferase 17
chr2_+_73385730 0.81 ENST00000484298.5
ALMS1 centrosome and basal body associated protein
chr3_-_112974912 0.78 ENST00000440122.6
ENST00000490004.1
CD200 receptor 1
chr6_+_39792298 0.77 ENST00000633794.1
ENST00000274867.9
dishevelled associated activator of morphogenesis 2
chr1_-_48400826 0.74 ENST00000371841.1
spermatogenesis associated 6
chr4_+_185396834 0.71 ENST00000335174.6
ankyrin repeat domain 37
chr3_-_105869035 0.69 ENST00000447441.6
ENST00000403724.5
ENST00000405772.5
Cbl proto-oncogene B
chr19_+_49513353 0.69 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr8_+_100158576 0.68 ENST00000388798.7
sperm associated antigen 1
chr13_-_85799400 0.66 ENST00000647374.2
SLIT and NTRK like family member 6
chr5_-_20575850 0.64 ENST00000507958.5
cadherin 18
chr19_+_55947832 0.63 ENST00000291971.7
ENST00000590542.1
NLR family pyrin domain containing 8
chr7_+_70596078 0.63 ENST00000644506.1
activator of transcription and developmental regulator AUTS2
chr16_+_31873772 0.62 ENST00000394846.7
ENST00000300870.15
zinc finger protein 267
chr3_+_42979281 0.61 ENST00000488863.5
ENST00000430121.3
golgi associated kinase 1A
chr1_-_145996567 0.61 ENST00000582401.6
thioredoxin interacting protein
chr5_+_142770367 0.61 ENST00000645722.2
ENST00000274498.9
Rho GTPase activating protein 26
chrX_+_77899440 0.60 ENST00000373335.4
ENST00000475465.1
ENST00000650309.2
ENST00000647835.1
cytochrome c oxidase subunit 7B
chr3_+_108822778 0.58 ENST00000295756.11
T cell receptor associated transmembrane adaptor 1
chr11_+_17276708 0.56 ENST00000531172.5
ENST00000529010.6
ENST00000533738.6
ENST00000323688.10
nucleobindin 2
chr6_-_119149124 0.55 ENST00000368475.8
family with sequence similarity 184 member A
chr9_-_134068012 0.53 ENST00000303407.12
bromodomain containing 3
chr3_+_108822759 0.53 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chr1_-_115089414 0.52 ENST00000433172.3
ENST00000369515.6
ENST00000369516.7
tetraspanin 2
chr1_+_43650118 0.51 ENST00000372396.4
lysine demethylase 4A
chr4_-_145180496 0.51 ENST00000447906.8
OTU deubiquitinase 4
chr7_+_149873956 0.50 ENST00000425642.3
ENST00000479613.5
ENST00000606024.5
ENST00000464662.5
ATPase H+ transporting V0 subunit e2
chr6_+_52186373 0.50 ENST00000648244.1
interleukin 17A
chr17_+_59331633 0.49 ENST00000312655.9
yippee like 2
chr6_+_26402237 0.49 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
butyrophilin subfamily 3 member A1
chr7_+_120950763 0.49 ENST00000339121.9
ENST00000315870.10
ENST00000445699.5
inhibitor of growth family member 3
chr7_-_141014939 0.49 ENST00000324787.10
ENST00000467334.1
mitochondrial ribosomal protein S33
chr10_-_28282086 0.48 ENST00000375719.7
ENST00000375732.5
membrane palmitoylated protein 7
chr20_+_19886506 0.47 ENST00000648440.1
Ras and Rab interactor 2
chr18_+_62523385 0.47 ENST00000588676.1
zinc finger CCHC-type containing 2
chr6_-_26271815 0.46 ENST00000614378.1
H3 clustered histone 8
chr6_+_36196710 0.46 ENST00000357641.10
bromodomain and PHD finger containing 3
chr15_-_77420135 0.46 ENST00000560626.6
pseudopodium enriched atypical kinase 1
chr14_+_100376398 0.46 ENST00000554998.5
ENST00000402312.8
ENST00000335290.10
ENST00000554175.5
WD repeat domain 25
chr15_-_77420087 0.45 ENST00000564328.5
ENST00000682557.1
ENST00000558305.5
pseudopodium enriched atypical kinase 1
chr14_+_75661186 0.45 ENST00000556977.5
ENST00000298832.14
ENST00000557636.5
ENST00000286650.9
tubulin tyrosine ligase like 5
chr15_+_73926443 0.44 ENST00000261921.8
lysyl oxidase like 1
chr3_-_41961989 0.44 ENST00000420927.5
ENST00000301831.9
ENST00000414606.1
unc-51 like kinase 4
chr6_-_24358036 0.44 ENST00000378454.8
doublecortin domain containing 2
chr9_+_101398841 0.43 ENST00000339664.7
ENST00000374861.7
ENST00000259395.4
ENST00000615466.1
zinc finger protein 189
chr4_-_1721313 0.43 ENST00000382936.8
ENST00000536901.1
ENST00000303277.6
transmembrane protein 129, E3 ubiquitin ligase
chr16_-_55833085 0.41 ENST00000360526.8
carboxylesterase 1
chr11_-_236326 0.41 ENST00000525237.1
ENST00000382743.9
ENST00000532956.5
ENST00000525319.5
ENST00000524564.5
sirtuin 3
chr19_-_41364119 0.40 ENST00000243578.8
B9 domain containing 2
chr11_-_125111708 0.40 ENST00000531909.5
ENST00000529530.1
transmembrane protein 218
chr12_+_14973020 0.39 ENST00000266395.3
phosphodiesterase 6H
chr19_-_41363930 0.38 ENST00000675972.1
B9 domain containing 2
chr5_-_55534955 0.38 ENST00000307259.9
ENST00000264775.9
phospholipid phosphatase 1
chr10_-_70382589 0.38 ENST00000373224.5
ENST00000446961.4
ENST00000357631.6
ENST00000358141.6
ENST00000395010.5
leucine rich repeat containing 20
chr22_-_21735744 0.37 ENST00000403503.1
yippee like 1
chr1_+_160400543 0.37 ENST00000368061.3
VANGL planar cell polarity protein 2
chr17_-_49764123 0.36 ENST00000240364.7
ENST00000506156.1
family with sequence similarity 117 member A
chr14_-_103715433 0.35 ENST00000554913.5
ENST00000555055.6
ENST00000554974.5
ENST00000553361.5
ENST00000555964.5
ENST00000556682.5
ENST00000553332.5
ENST00000352127.11
X-ray repair cross complementing 3
chr8_+_42152946 0.34 ENST00000518421.5
ENST00000174653.3
ENST00000396926.8
ENST00000521280.5
ENST00000522288.5
adaptor related protein complex 3 subunit mu 2
chr2_-_151261839 0.34 ENST00000331426.6
RNA binding motif protein 43
chr22_+_41381923 0.33 ENST00000266304.9
TEF transcription factor, PAR bZIP family member
chr4_+_112637120 0.32 ENST00000509061.5
ENST00000344442.10
ENST00000508577.5
ENST00000513553.5
La ribonucleoprotein 7, transcriptional regulator
chr20_-_51802509 0.32 ENST00000371539.7
ENST00000217086.9
spalt like transcription factor 4
chr17_+_75456618 0.31 ENST00000314256.12
ENST00000582186.5
ENST00000582455.5
ENST00000581252.5
ENST00000579208.5
transmembrane protein 94
chr18_-_23437927 0.31 ENST00000578520.5
ENST00000383233.8
transmembrane protein 241
chr4_-_112636858 0.31 ENST00000503172.5
ENST00000505019.6
ENST00000309071.9
zinc finger GRF-type containing 1
chr12_-_44876294 0.29 ENST00000429094.7
ENST00000551601.5
ENST00000549027.5
ENST00000452445.6
neural EGFL like 2
chr12_+_118136086 0.29 ENST00000261313.3
phosphatidylethanolamine binding protein 1
chr7_-_141973773 0.29 ENST00000547270.1
taste 2 receptor member 38
chr1_-_92486916 0.29 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr3_+_179562886 0.28 ENST00000450518.6
ENST00000392662.5
ENST00000429709.7
ENST00000490364.1
actin like 6A
chr1_+_241532121 0.28 ENST00000366558.7
kynurenine 3-monooxygenase
chr17_+_7407838 0.28 ENST00000302926.7
neuroligin 2
chr11_+_77821125 0.28 ENST00000526415.5
ENST00000393427.6
ENST00000527134.5
ENST00000304716.12
ENST00000630098.2
adipogenesis associated Mth938 domain containing
chr16_-_66550142 0.28 ENST00000417693.8
ENST00000299697.12
ENST00000451102.7
thymidine kinase 2
chr6_+_26402289 0.28 ENST00000414912.2
butyrophilin subfamily 3 member A1
chr12_+_7711418 0.27 ENST00000345088.3
developmental pluripotency associated 3
chr1_+_27934980 0.27 ENST00000373894.8
sphingomyelin phosphodiesterase acid like 3B
chr14_-_99480831 0.26 ENST00000331768.10
ENST00000630307.2
SET domain containing 3, actin histidine methyltransferase
chr4_+_154781344 0.26 ENST00000510397.5
RNA binding motif protein 46
chr7_+_55365317 0.25 ENST00000254770.3
LanC like 2
chr1_-_236065079 0.25 ENST00000264187.7
ENST00000366595.7
nidogen 1
chr14_+_21825453 0.25 ENST00000390432.2
T cell receptor alpha variable 10
chr11_-_129024157 0.24 ENST00000392657.7
Rho GTPase activating protein 32
chr19_-_10380454 0.24 ENST00000530829.1
ENST00000529370.5
tyrosine kinase 2
chr7_-_77798359 0.24 ENST00000257663.4
transmembrane protein 60
chr12_-_9607903 0.24 ENST00000229402.4
killer cell lectin like receptor B1
chr7_-_87220567 0.24 ENST00000433078.5
transmembrane protein 243
chr11_+_77821187 0.24 ENST00000525409.5
adipogenesis associated Mth938 domain containing
chr17_-_79797030 0.23 ENST00000269385.9
chromobox 8
chr17_+_44070729 0.23 ENST00000269097.9
glucose-6-phosphatase catalytic subunit 3
chr13_-_41019289 0.23 ENST00000239882.7
E74 like ETS transcription factor 1
chr17_+_18183803 0.23 ENST00000399138.5
alkB homolog 5, RNA demethylase
chr6_-_31158073 0.23 ENST00000507751.5
ENST00000448162.6
ENST00000502557.5
ENST00000503420.5
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.5
ENST00000396263.6
ENST00000508683.5
ENST00000428174.1
ENST00000448141.6
ENST00000507829.5
ENST00000455279.6
ENST00000376266.9
coiled-coil alpha-helical rod protein 1
chr18_+_62523002 0.23 ENST00000269499.10
zinc finger CCHC-type containing 2
chr13_+_33016415 0.23 ENST00000380099.4
klotho
chr22_-_17159220 0.22 ENST00000399852.3
ENST00000336737.8
haloacid dehalogenase like hydrolase domain containing 5
chrX_-_47650488 0.22 ENST00000247161.7
ENST00000376983.8
ENST00000343894.8
ETS transcription factor ELK1
chr1_+_27935110 0.22 ENST00000549094.1
sphingomyelin phosphodiesterase acid like 3B
chr4_-_65670478 0.22 ENST00000613740.5
ENST00000622150.4
ENST00000511294.1
EPH receptor A5
chr3_-_165837412 0.22 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
butyrylcholinesterase
chr12_-_44875647 0.22 ENST00000395487.6
neural EGFL like 2
chr6_-_31862809 0.22 ENST00000375631.5
neuraminidase 1
chr20_-_51802433 0.22 ENST00000395997.3
spalt like transcription factor 4
chr17_+_18183052 0.22 ENST00000541285.1
alkB homolog 5, RNA demethylase
chr7_+_138460238 0.22 ENST00000343526.9
tripartite motif containing 24
chr12_+_51951663 0.21 ENST00000257963.9
ENST00000541224.5
ENST00000426655.6
ENST00000536420.5
ENST00000415850.6
activin A receptor type 1B
chr20_+_18507520 0.21 ENST00000336714.8
ENST00000646240.1
ENST00000450074.6
ENST00000262544.6
SEC23 homolog B, COPII coat complex component
chr11_+_76445001 0.21 ENST00000533988.5
ENST00000524490.5
ENST00000334736.7
ENST00000533972.5
EMSY transcriptional repressor, BRCA2 interacting
chr1_-_248277976 0.21 ENST00000641220.1
olfactory receptor family 2 subfamily T member 33
chr3_-_157503574 0.21 ENST00000494677.5
ENST00000468233.5
ventricular zone expressed PH domain containing 1
chr22_-_21735776 0.20 ENST00000339468.8
yippee like 1
chr13_+_48256214 0.20 ENST00000650237.1
integral membrane protein 2B
chr1_+_236795254 0.20 ENST00000366577.10
ENST00000674797.2
5-methyltetrahydrofolate-homocysteine methyltransferase
chr12_-_56360084 0.19 ENST00000314128.9
ENST00000557235.5
ENST00000651915.1
signal transducer and activator of transcription 2
chr4_-_137532452 0.18 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr1_-_1778399 0.18 ENST00000341426.9
NAD kinase
chr2_+_201071984 0.18 ENST00000237889.9
ENST00000433898.5
ENST00000684175.1
ENST00000682325.1
ENST00000454214.1
ENST00000684420.1
NADH:ubiquinone oxidoreductase subunit B3
chr19_+_7629771 0.18 ENST00000594797.6
ENST00000456958.7
ENST00000601406.5
PET100 cytochrome c oxidase chaperone
chr2_-_27380715 0.17 ENST00000323703.11
ENST00000436006.1
zinc finger protein 513
chr1_-_173917281 0.17 ENST00000367698.4
serpin family C member 1
chrX_+_19343893 0.17 ENST00000540249.5
ENST00000545074.5
ENST00000379806.9
ENST00000423505.5
ENST00000422285.7
ENST00000417819.5
ENST00000355808.9
ENST00000379805.3
pyruvate dehydrogenase E1 subunit alpha 1
chr6_+_132538290 0.17 ENST00000434551.2
trace amine associated receptor 9
chr12_-_81758641 0.17 ENST00000552948.5
ENST00000548586.5
PTPRF interacting protein alpha 2
chr2_+_108588286 0.17 ENST00000332345.10
LIM zinc finger domain containing 1
chr17_+_43171187 0.17 ENST00000542611.5
ENST00000590996.6
ENST00000589872.1
NBR1 autophagy cargo receptor
chr1_+_27935022 0.17 ENST00000411604.5
ENST00000373888.8
sphingomyelin phosphodiesterase acid like 3B
chr6_-_84764581 0.17 ENST00000369663.10
T-box transcription factor 18
chr6_+_110180418 0.16 ENST00000368930.5
ENST00000307731.2
cell division cycle 40
chr4_-_65670339 0.16 ENST00000273854.7
EPH receptor A5
chr9_+_101533840 0.16 ENST00000389120.8
ENST00000374819.6
ENST00000479306.5
ring finger protein 20
chr9_-_125143457 0.16 ENST00000373549.8
ENST00000336505.11
suppressor of cancer cell invasion
chr3_-_105868964 0.16 ENST00000394030.8
Cbl proto-oncogene B
chrX_-_154097668 0.16 ENST00000407218.5
ENST00000303391.11
ENST00000453960.7
methyl-CpG binding protein 2
chr17_-_64130813 0.15 ENST00000606895.2
endoplasmic reticulum to nucleus signaling 1
chr19_-_10380558 0.15 ENST00000524462.5
ENST00000525621.6
ENST00000531836.5
tyrosine kinase 2
chr8_+_91249307 0.15 ENST00000309536.6
ENST00000276609.8
solute carrier family 26 member 7
chr2_-_74178802 0.15 ENST00000396049.5
MOB kinase activator 1A
chr17_-_46579651 0.14 ENST00000573185.5
ENST00000570550.5
ENST00000445552.6
ENST00000329240.10
ENST00000622488.6
ENST00000336125.6
ADP ribosylation factor like GTPase 17A
chr6_-_33418093 0.14 ENST00000488034.6
cutA divalent cation tolerance homolog
chr19_-_54159696 0.14 ENST00000222224.4
leukocyte receptor cluster member 1
chr16_+_31713231 0.13 ENST00000539915.5
ENST00000316491.13
ENST00000398696.3
ENST00000534369.1
ENST00000530881.5
ENST00000529515.1
zinc finger protein 720
chr4_+_112637514 0.13 ENST00000651579.1
La ribonucleoprotein 7, transcriptional regulator
chr6_+_127577168 0.13 ENST00000329722.8
chromosome 6 open reading frame 58
chr19_-_12722547 0.13 ENST00000592287.5
transportin 2
chr6_-_33418077 0.13 ENST00000488478.5
cutA divalent cation tolerance homolog
chr5_+_174724549 0.13 ENST00000239243.7
ENST00000507785.2
msh homeobox 2
chr17_-_76737321 0.12 ENST00000359995.10
ENST00000508921.7
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
serine and arginine rich splicing factor 2
chr19_-_46634685 0.12 ENST00000300873.4
G protein subunit gamma 8
chr6_-_33417878 0.12 ENST00000440279.7
ENST00000607266.5
cutA divalent cation tolerance homolog
chr20_+_257716 0.12 ENST00000382376.4
defensin beta 132
chr11_-_125111579 0.12 ENST00000532156.5
ENST00000532407.5
ENST00000279968.8
ENST00000527766.5
ENST00000529583.5
ENST00000524373.5
ENST00000527271.5
ENST00000526175.5
ENST00000529609.5
ENST00000682305.1
ENST00000533273.1
transmembrane protein 218
chrX_-_24672654 0.12 ENST00000379145.5
phosphate cytidylyltransferase 1, choline, beta
chr20_+_34194569 0.12 ENST00000568305.5
agouti signaling protein
chr1_+_100351698 0.12 ENST00000644676.1
cell division cycle 14A
chr3_+_63819293 0.12 ENST00000295896.13
chromosome 3 open reading frame 49
chr1_+_40247926 0.11 ENST00000372766.4
transmembrane and coiled-coil domains 2
chr1_+_207325629 0.11 ENST00000618707.2
CD55 molecule (Cromer blood group)
chr6_-_33418125 0.11 ENST00000492510.1
ENST00000374500.10
cutA divalent cation tolerance homolog
chr1_-_13285154 0.11 ENST00000357367.6
ENST00000614831.1
PRAME family member 8
chr7_+_100612430 0.11 ENST00000379527.6
motile sperm domain containing 3
chr14_+_103715724 0.11 ENST00000216602.10
zinc finger FYVE-type containing 21
chr14_-_52069228 0.11 ENST00000617139.4
nidogen 2
chr2_-_201071579 0.11 ENST00000453765.5
ENST00000452799.5
ENST00000446678.5
ENST00000418596.7
ENST00000681958.1
family with sequence similarity 126 member B
chr8_+_9555900 0.11 ENST00000310430.11
ENST00000520408.5
ENST00000522110.1
tankyrase
chr11_-_101129806 0.10 ENST00000325455.10
ENST00000617858.4
ENST00000619228.2
progesterone receptor
chr11_-_18526885 0.10 ENST00000251968.4
ENST00000536719.5
tumor susceptibility 101
chr6_-_33418046 0.10 ENST00000494751.5
ENST00000374496.3
cutA divalent cation tolerance homolog
chr7_+_100612522 0.10 ENST00000393950.7
ENST00000424091.2
motile sperm domain containing 3
chr4_+_112637456 0.10 ENST00000505034.5
ENST00000324052.10
La ribonucleoprotein 7, transcriptional regulator
chr7_+_21543020 0.09 ENST00000409508.8
ENST00000620169.4
ENST00000328843.10
dynein axonemal heavy chain 11
chr17_-_46361718 0.09 ENST00000575960.5
ENST00000575698.5
ENST00000571246.5
ENST00000434041.6
ENST00000656849.1
ENST00000570618.5
ENST00000450673.4
ENST00000622877.4
ADP ribosylation factor like GTPase 17B
chr11_-_124310837 0.09 ENST00000357821.2
olfactory receptor family 8 subfamily D member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.3 2.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.3 1.0 GO:0061055 myotome development(GO:0061055)
0.2 0.7 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2 1.4 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.2 1.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.4 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.4 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.4 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.9 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.8 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.4 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.5 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.3 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.3 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.3 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.1 1.0 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.5 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 0.3 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.3 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.6 GO:2000620 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.5 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 2.3 GO:0007141 male meiosis I(GO:0007141)
0.1 3.7 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.2 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.1 3.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.7 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.2 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.7 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.1 GO:0034183 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 1.2 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.4 GO:0008354 germ cell migration(GO:0008354)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475) double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.8 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.6 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.2 GO:0070054 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.5 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.5 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.2 0.7 GO:0097224 sperm connecting piece(GO:0097224)
0.2 1.2 GO:0071942 XPC complex(GO:0071942)
0.2 2.6 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 1.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.0 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.6 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.9 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 2.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.8 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.3 GO:0001940 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.5 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.6 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 2.5 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.1 1.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 2.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.4 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.3 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.7 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.4 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 1.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 3.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.4 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.0 0.1 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.4 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.8 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 2.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 3.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 1.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants