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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for MAFA

Z-value: 0.70

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Transcription factors associated with MAFA

Gene Symbol Gene ID Gene Info
MAFA
ENSG00000182759.4 MAFA

Activity profile of MAFA motif

Sorted Z-values of MAFA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFA

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_+_32934383 2.60 ENST00000551634.6
NPAS3
neuronal PAS domain protein 3
chr9_+_122371036 1.90 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
PTGS1
prostaglandin-endoperoxide synthase 1
chr10_-_77637902 1.77 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr2_-_25982471 1.41 ENST00000264712.8
KIF3C
kinesin family member 3C
chr10_-_77637558 1.37 ENST00000372421.10
ENST00000639370.1
ENST00000640773.1
ENST00000638895.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr11_+_118956289 1.35 ENST00000264031.3
UPK2
uroplakin 2
chr5_-_39270623 1.33 ENST00000512138.1
ENST00000646045.2
FYB1
FYN binding protein 1
chr10_-_77637444 1.27 ENST00000639205.1
ENST00000639498.1
ENST00000372408.7
ENST00000372403.9
ENST00000640626.1
ENST00000404857.6
ENST00000638252.1
ENST00000640029.1
ENST00000640934.1
ENST00000639823.1
ENST00000372437.6
ENST00000639344.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr9_+_122371014 1.25 ENST00000362012.7
PTGS1
prostaglandin-endoperoxide synthase 1
chr17_-_43545636 1.20 ENST00000393664.6
ETV4
ETS variant transcription factor 4
chr3_-_86991135 1.02 ENST00000398399.7
VGLL3
vestigial like family member 3
chr19_+_42313298 1.00 ENST00000301204.8
ENST00000673205.1
TMEM145
transmembrane protein 145
chrX_-_43882411 0.90 ENST00000378069.5
MAOB
monoamine oxidase B
chr16_+_56565070 0.90 ENST00000219162.4
MT4
metallothionein 4
chr10_-_77637721 0.88 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr19_+_42313374 0.88 ENST00000598766.1
ENST00000673187.1
TMEM145
transmembrane protein 145
chr15_+_80404320 0.82 ENST00000303329.9
ENST00000622346.4
ARNT2
aryl hydrocarbon receptor nuclear translocator 2
chr2_+_118088432 0.80 ENST00000245787.9
INSIG2
insulin induced gene 2
chr19_-_50637939 0.79 ENST00000338916.8
SYT3
synaptotagmin 3
chr10_-_77637789 0.76 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr19_-_42594918 0.63 ENST00000244336.10
CEACAM8
CEA cell adhesion molecule 8
chr20_+_325536 0.62 ENST00000342665.5
SOX12
SRY-box transcription factor 12
chr2_+_85584402 0.60 ENST00000306384.5
VAMP5
vesicle associated membrane protein 5
chr22_+_22818994 0.58 ENST00000390316.2
IGLV3-9
immunoglobulin lambda variable 3-9
chr2_+_190880834 0.58 ENST00000338435.8
GLS
glutaminase
chr10_+_119207560 0.54 ENST00000392870.3
GRK5
G protein-coupled receptor kinase 5
chr20_-_23086316 0.53 ENST00000246006.5
CD93
CD93 molecule
chr2_+_114442616 0.51 ENST00000410059.6
DPP10
dipeptidyl peptidase like 10
chr10_-_77637633 0.50 ENST00000638223.1
ENST00000639544.1
ENST00000640807.1
ENST00000434208.6
ENST00000626620.3
ENST00000638575.1
ENST00000638759.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr2_+_190880809 0.50 ENST00000320717.8
GLS
glutaminase
chr13_-_113864062 0.49 ENST00000327773.7
GAS6
growth arrest specific 6
chr17_-_10421944 0.48 ENST00000403437.2
MYH8
myosin heavy chain 8
chr5_+_140360187 0.48 ENST00000506757.7
ENST00000506545.5
ENST00000432095.6
ENST00000507527.1
SLC4A9
solute carrier family 4 member 9
chr7_-_101217569 0.47 ENST00000223127.8
PLOD3
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
chr5_-_22853320 0.46 ENST00000504376.6
ENST00000382254.6
CDH12
cadherin 12
chr17_-_49848017 0.46 ENST00000326219.5
ENST00000334568.8
ENST00000352793.6
ENST00000398154.5
ENST00000436235.5
TAC4
tachykinin precursor 4
chr19_-_4124082 0.46 ENST00000394867.8
ENST00000262948.10
MAP2K2
mitogen-activated protein kinase kinase 2
chr16_-_46831134 0.42 ENST00000394806.6
ENST00000285697.9
C16orf87
chromosome 16 open reading frame 87
chrX_-_64205680 0.42 ENST00000374869.8
AMER1
APC membrane recruitment protein 1
chr12_-_105084439 0.41 ENST00000258494.14
ALDH1L2
aldehyde dehydrogenase 1 family member L2
chr12_-_21501551 0.41 ENST00000421138.6
ENST00000539672.1
ENST00000542432.5
ENST00000444129.7
ENST00000536964.5
ENST00000536240.5
ENST00000396093.7
ENST00000314748.10
RECQL
RecQ like helicase
chr7_-_99919479 0.41 ENST00000354241.5
TRIM4
tripartite motif containing 4
chr9_+_2621556 0.40 ENST00000680746.1
VLDLR
very low density lipoprotein receptor
chr17_+_41105332 0.39 ENST00000391415.1
ENST00000617453.1
KRTAP4-9
keratin associated protein 4-9
chr17_-_41168219 0.39 ENST00000391356.4
KRTAP4-3
keratin associated protein 4-3
chr6_+_96924720 0.39 ENST00000369261.9
KLHL32
kelch like family member 32
chr22_-_30546682 0.39 ENST00000402034.6
SEC14L6
SEC14 like lipid binding 6
chr7_+_129126518 0.39 ENST00000467614.2
ENSG00000230626.4
novel protein similar to mitogen-activated protein kinase kinase 2 MAP2K2
chr9_+_2621766 0.38 ENST00000382100.8
VLDLR
very low density lipoprotein receptor
chr22_+_22720615 0.37 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr14_-_50312154 0.35 ENST00000555610.1
ENST00000261699.8
L2HGDH
L-2-hydroxyglutarate dehydrogenase
chr7_-_22500152 0.34 ENST00000406890.6
ENST00000678116.1
ENST00000424363.5
STEAP1B
STEAP family member 1B
chr8_+_84183534 0.34 ENST00000518566.5
RALYL
RALY RNA binding protein like
chr17_+_40309161 0.33 ENST00000254066.10
RARA
retinoic acid receptor alpha
chr7_+_135557904 0.33 ENST00000285968.11
NUP205
nucleoporin 205
chr14_+_80955043 0.32 ENST00000541158.6
TSHR
thyroid stimulating hormone receptor
chr17_+_43211835 0.31 ENST00000588693.5
ENST00000588659.5
ENST00000541594.5
ENST00000536052.5
ENST00000612339.4
TMEM106A
transmembrane protein 106A
chr4_-_10116724 0.29 ENST00000502702.5
WDR1
WD repeat domain 1
chr7_+_152025632 0.28 ENST00000430044.7
ENST00000431668.1
ENST00000446096.5
ENST00000423337.5
GALNT11
polypeptide N-acetylgalactosaminyltransferase 11
chr17_-_41572052 0.28 ENST00000588431.1
ENST00000246662.9
KRT9
keratin 9
chr1_-_153312919 0.28 ENST00000683862.1
PGLYRP3
peptidoglycan recognition protein 3
chr9_+_2622053 0.27 ENST00000681306.1
ENST00000681618.1
VLDLR
very low density lipoprotein receptor
chr3_-_126558926 0.26 ENST00000318225.3
C3orf22
chromosome 3 open reading frame 22
chr14_-_50312212 0.25 ENST00000555423.5
ENST00000267436.9
ENST00000421284.7
L2HGDH
L-2-hydroxyglutarate dehydrogenase
chr17_+_27609836 0.24 ENST00000582410.5
KSR1
kinase suppressor of ras 1
chr5_+_177087412 0.24 ENST00000513166.1
FGFR4
fibroblast growth factor receptor 4
chr6_+_42929127 0.23 ENST00000394142.7
CNPY3
canopy FGF signaling regulator 3
chr7_+_150379316 0.23 ENST00000483664.5
ENST00000329630.10
ENSG00000284048.2
ZNF775
novel transcript
zinc finger protein 775
chr15_-_89912882 0.23 ENST00000398333.7
ENST00000357484.10
ARPIN-AP3S2
ARPIN
ARPIN-AP3S2 readthrough
actin related protein 2/3 complex inhibitor
chr21_+_39867387 0.23 ENST00000328619.10
PCP4
Purkinje cell protein 4
chr10_-_79949098 0.22 ENST00000372292.8
SFTPD
surfactant protein D
chr7_+_142598016 0.22 ENST00000620773.1
TRBV16
T cell receptor beta variable 16
chr17_-_78132407 0.21 ENST00000322914.7
TMC6
transmembrane channel like 6
chr1_-_37859583 0.21 ENST00000373036.5
MTF1
metal regulatory transcription factor 1
chr20_-_59007807 0.20 ENST00000680386.1
CTSZ
cathepsin Z
chr11_-_777467 0.20 ENST00000397472.6
ENST00000524550.5
ENST00000319863.13
ENST00000526325.5
GATD1
glutamine amidotransferase like class 1 domain containing 1
chr9_-_128127711 0.19 ENST00000449878.1
ENST00000338961.11
ENST00000678174.1
PTGES2
prostaglandin E synthase 2
chr1_+_65992389 0.19 ENST00000423207.6
PDE4B
phosphodiesterase 4B
chr7_-_149126306 0.17 ENST00000483014.1
ENST00000378061.7
ZNF425
zinc finger protein 425
chrX_-_93673558 0.17 ENST00000475430.2
ENST00000373079.4
NAP1L3
nucleosome assembly protein 1 like 3
chr14_+_80955577 0.17 ENST00000642209.1
ENST00000298171.7
TSHR
thyroid stimulating hormone receptor
chr11_+_24497155 0.17 ENST00000529015.5
ENST00000533227.5
LUZP2
leucine zipper protein 2
chr9_-_28670285 0.16 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
LINGO2
leucine rich repeat and Ig domain containing 2
chr12_+_56152579 0.16 ENST00000551834.5
ENST00000552568.5
MYL6B
myosin light chain 6B
chr11_-_63015831 0.16 ENST00000430500.6
ENST00000336232.7
SLC22A8
solute carrier family 22 member 8
chr1_+_224616302 0.16 ENST00000272133.4
CNIH3
cornichon family AMPA receptor auxiliary protein 3
chr8_-_88327475 0.16 ENST00000286614.11
MMP16
matrix metallopeptidase 16
chr3_+_196712298 0.15 ENST00000392391.9
ENST00000296333.10
PIGX
phosphatidylinositol glycan anchor biosynthesis class X
chr9_-_129620743 0.15 ENST00000619117.1
ENST00000372478.4
C9orf50
chromosome 9 open reading frame 50
chr22_+_22375984 0.14 ENST00000390296.2
IGLV5-45
immunoglobulin lambda variable 5-45
chr5_+_177086867 0.14 ENST00000503708.5
ENST00000393648.6
ENST00000514472.1
ENST00000502906.5
ENST00000292408.9
ENST00000510911.5
FGFR4
fibroblast growth factor receptor 4
chr19_+_35612729 0.14 ENST00000203166.10
HAUS5
HAUS augmin like complex subunit 5
chr9_+_137139139 0.14 ENST00000371561.8
GRIN1
glutamate ionotropic receptor NMDA type subunit 1
chr20_-_33004307 0.14 ENST00000420875.5
ENST00000375519.2
ENST00000375523.7
ENST00000356173.8
SUN5
Sad1 and UNC84 domain containing 5
chrX_+_72776873 0.13 ENST00000334036.10
DMRTC1B
DMRT like family C1B
chr10_-_48493641 0.13 ENST00000417247.6
ARHGAP22
Rho GTPase activating protein 22
chr3_+_75906666 0.13 ENST00000487694.7
ENST00000602589.5
ROBO2
roundabout guidance receptor 2
chr5_+_177426701 0.13 ENST00000507633.5
ENST00000393576.7
ENST00000355958.9
ENST00000528793.5
ENST00000512684.1
GRK6
G protein-coupled receptor kinase 6
chr22_-_26618026 0.13 ENST00000647684.1
CRYBB1
crystallin beta B1
chr1_+_77888612 0.12 ENST00000334785.12
NEXN
nexilin F-actin binding protein
chr12_+_54549586 0.12 ENST00000243052.8
PDE1B
phosphodiesterase 1B
chr17_-_3433841 0.12 ENST00000248384.1
OR1E2
olfactory receptor family 1 subfamily E member 2
chr11_+_24496988 0.11 ENST00000336930.11
LUZP2
leucine zipper protein 2
chr19_-_48044037 0.11 ENST00000293255.3
CABP5
calcium binding protein 5
chr2_-_48755718 0.11 ENST00000294954.12
ENST00000403273.5
ENST00000401907.5
LHCGR
luteinizing hormone/choriogonadotropin receptor
chr4_-_47837949 0.10 ENST00000505909.5
ENST00000273857.9
ENST00000502252.5
CORIN
corin, serine peptidase
chr7_-_135211313 0.10 ENST00000682802.1
ENST00000683848.1
ENST00000354475.5
WDR91
WD repeat domain 91
chrX_-_72943837 0.10 ENST00000615063.2
DMRTC1
DMRT like family C1
chr4_-_151015713 0.10 ENST00000357115.9
LRBA
LPS responsive beige-like anchor protein
chr17_+_32991844 0.09 ENST00000269053.8
SPACA3
sperm acrosome associated 3
chr12_+_21501780 0.09 ENST00000229314.10
ENST00000542038.5
ENST00000540141.5
ENST00000631252.2
GOLT1B
golgi transport 1B
chr1_+_77888490 0.09 ENST00000401035.7
ENST00000330010.12
NEXN
nexilin F-actin binding protein
chr1_+_163069353 0.09 ENST00000531057.5
ENST00000527809.5
ENST00000367908.8
ENST00000367909.11
RGS4
regulator of G protein signaling 4
chr16_+_56191476 0.08 ENST00000262493.12
GNAO1
G protein subunit alpha o1
chr17_+_63477052 0.08 ENST00000290866.10
ENST00000428043.5
ACE
angiotensin I converting enzyme
chr7_-_108528155 0.08 ENST00000453085.1
PNPLA8
patatin like phospholipase domain containing 8
chr19_+_35268921 0.08 ENST00000222305.8
ENST00000343550.9
USF2
upstream transcription factor 2, c-fos interacting
chr11_-_63015804 0.08 ENST00000535878.5
ENST00000545207.5
SLC22A8
solute carrier family 22 member 8
chr17_-_41149823 0.08 ENST00000343246.6
KRTAP4-5
keratin associated protein 4-5
chr19_+_12838437 0.07 ENST00000251472.9
MAST1
microtubule associated serine/threonine kinase 1
chr19_+_35666515 0.06 ENST00000617999.4
ENST00000616789.4
UPK1A
uroplakin 1A
chr6_-_99349647 0.06 ENST00000389677.6
FAXC
failed axon connections homolog, metaxin like GST domain containing
chr3_+_141402322 0.05 ENST00000510338.5
ENST00000504673.5
ZBTB38
zinc finger and BTB domain containing 38
chr1_-_203175783 0.05 ENST00000621380.1
ENST00000255416.9
MYBPH
myosin binding protein H
chr6_-_73521783 0.05 ENST00000331523.7
ENST00000356303.7
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr4_+_73740541 0.04 ENST00000401931.1
ENST00000307407.8
CXCL8
C-X-C motif chemokine ligand 8
chr3_+_185586270 0.04 ENST00000296257.10
SENP2
SUMO specific peptidase 2
chr16_+_1309136 0.04 ENST00000325437.9
UBE2I
ubiquitin conjugating enzyme E2 I
chr19_+_35269065 0.04 ENST00000595068.5
ENST00000379134.7
ENST00000594064.5
ENST00000598058.1
USF2
upstream transcription factor 2, c-fos interacting
chr3_+_184299198 0.03 ENST00000417952.5
ENST00000310118.9
PSMD2
proteasome 26S subunit, non-ATPase 2
chr8_-_131040890 0.03 ENST00000286355.10
ADCY8
adenylate cyclase 8
chrX_-_153875847 0.03 ENST00000361699.8
ENST00000361981.7
L1CAM
L1 cell adhesion molecule
chr15_-_40755223 0.03 ENST00000560460.5
ENST00000338376.8
ENST00000560905.1
RMDN3
regulator of microtubule dynamics 3
chr12_-_1918473 0.03 ENST00000586184.5
ENST00000587995.5
ENST00000585732.1
CACNA2D4
calcium voltage-gated channel auxiliary subunit alpha2delta 4
chr3_-_48717166 0.02 ENST00000413654.5
ENST00000454335.5
ENST00000440424.5
ENST00000449610.5
ENST00000443964.1
ENST00000417896.1
ENST00000413298.5
ENST00000449563.5
ENST00000443853.5
ENST00000437427.5
ENST00000446860.5
ENST00000412850.5
ENST00000424035.1
ENST00000340879.8
ENST00000431721.6
ENST00000434860.1
ENST00000328631.10
ENST00000432678.6
IP6K2
inositol hexakisphosphate kinase 2
chr21_+_44600597 0.02 ENST00000609664.2
KRTAP10-7
keratin associated protein 10-7
chr1_-_31937769 0.02 ENST00000649841.1
ENST00000534796.5
PTP4A2
protein tyrosine phosphatase 4A2
chr22_+_22244776 0.01 ENST00000302273.2
ENST00000403807.4
VPREB1
V-set pre-B cell surrogate light chain 1
chr12_-_122730828 0.01 ENST00000432564.3
HCAR1
hydroxycarboxylic acid receptor 1
chr1_-_42766978 0.00 ENST00000372526.2
ENST00000236040.8
ENST00000296388.10
ENST00000397054.7
P3H1
prolyl 3-hydroxylase 1
chr22_+_22409755 0.00 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr1_+_42767241 0.00 ENST00000372525.7
C1orf50
chromosome 1 open reading frame 50

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.5 GO:0034465 response to carbon monoxide(GO:0034465)
0.3 1.9 GO:0019236 response to pheromone(GO:0019236)
0.2 1.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 0.5 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.2 3.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.4 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1 1.1 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.9 GO:0010044 response to aluminum ion(GO:0010044) negative regulation of serotonin secretion(GO:0014063)
0.1 0.5 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.5 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.3 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.3 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 0.5 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.4 GO:1903412 response to bile acid(GO:1903412)
0.0 0.8 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.3 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0043449 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.0 0.4 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0071373 primary ovarian follicle growth(GO:0001545) cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.4 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 1.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.6 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.1 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.0 0.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.3 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 6.1 GO:0005901 caveola(GO:0005901)
0.0 1.1 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 1.4 GO:0097542 ciliary tip(GO:0097542)
0.0 3.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 0.6 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.0 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 1.4 GO:0070821 tertiary granule membrane(GO:0070821)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.6 3.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 1.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.2 1.1 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.4 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.4 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 0.5 GO:0050211 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1 0.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.5 GO:0017018 myosin phosphatase activity(GO:0017018)
0.1 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.5 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.2 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.4 REACTOME KINESINS Genes involved in Kinesins
0.0 1.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions