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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for MIXL1_GSX1_BSX_MEOX2_LHX4
Z-value: 0.62
Motif logo
Transcription factors associated with MIXL1_GSX1_BSX_MEOX2_LHX4
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
MIXL1
|
ENSG00000185155.12 | MIXL1 |
|
GSX1
|
ENSG00000169840.5 | GSX1 |
|
BSX
|
ENSG00000188909.5 | BSX |
|
MEOX2
|
ENSG00000106511.6 | MEOX2 |
|
LHX4
|
ENSG00000121454.6 | LHX4 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MEOX2 | hg38_v1_chr7_-_15686671_15686689 | -0.41 | 2.5e-02 | Click! |
| LHX4 | hg38_v1_chr1_+_180230257_180230291 | -0.37 | 4.3e-02 | Click! |
| GSX1 | hg38_v1_chr13_+_27792479_27792485 | 0.28 | 1.3e-01 | Click! |
| MIXL1 | hg38_v1_chr1_+_226223618_226223670 | -0.16 | 3.9e-01 | Click! |
Activity profile of MIXL1_GSX1_BSX_MEOX2_LHX4 motif
Sorted Z-values of MIXL1_GSX1_BSX_MEOX2_LHX4 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 4.2 | GO:0034769 | basement membrane disassembly(GO:0034769) |
| 0.5 | 1.6 | GO:1904397 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397) |
| 0.5 | 1.5 | GO:1990922 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 0.4 | 1.7 | GO:0002399 | MHC class II protein complex assembly(GO:0002399) |
| 0.4 | 1.1 | GO:0030505 | inorganic diphosphate transport(GO:0030505) |
| 0.3 | 1.0 | GO:0072099 | apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) |
| 0.3 | 0.9 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 0.3 | 2.1 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.2 | 0.6 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 0.2 | 0.6 | GO:0061341 | non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) |
| 0.2 | 1.3 | GO:0048165 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731) |
| 0.2 | 0.7 | GO:1904383 | response to sodium phosphate(GO:1904383) |
| 0.2 | 1.3 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.2 | 0.5 | GO:1904862 | inhibitory synapse assembly(GO:1904862) |
| 0.2 | 0.7 | GO:1903173 | phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173) |
| 0.2 | 2.8 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
| 0.2 | 0.5 | GO:0061565 | dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571) |
| 0.1 | 3.5 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.1 | 1.0 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.1 | 1.6 | GO:0032277 | negative regulation of gonadotropin secretion(GO:0032277) |
| 0.1 | 0.4 | GO:0072023 | thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233) |
| 0.1 | 0.8 | GO:0061743 | motor learning(GO:0061743) |
| 0.1 | 0.7 | GO:0072573 | propionate metabolic process(GO:0019541) cellular response to progesterone stimulus(GO:0071393) tolerance induction to lipopolysaccharide(GO:0072573) |
| 0.1 | 0.8 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.1 | 1.0 | GO:0060287 | epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) |
| 0.1 | 0.7 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 0.1 | 0.4 | GO:0006711 | estrogen catabolic process(GO:0006711) |
| 0.1 | 0.5 | GO:0061055 | myotome development(GO:0061055) |
| 0.1 | 1.0 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.1 | 1.4 | GO:0006824 | cobalt ion transport(GO:0006824) |
| 0.1 | 0.3 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 0.1 | 0.4 | GO:0051758 | homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758) |
| 0.1 | 0.8 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.1 | 0.4 | GO:0035513 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
| 0.1 | 0.4 | GO:0099543 | positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) |
| 0.1 | 0.3 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.1 | 0.3 | GO:0071140 | resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140) |
| 0.1 | 1.2 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.1 | 1.3 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.1 | 0.3 | GO:0021530 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 0.1 | 0.9 | GO:0034144 | negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) |
| 0.1 | 1.0 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.1 | 0.2 | GO:0072501 | cellular divalent inorganic anion homeostasis(GO:0072501) |
| 0.1 | 0.3 | GO:1904204 | regulation of skeletal muscle hypertrophy(GO:1904204) |
| 0.1 | 0.3 | GO:0075732 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 0.1 | 0.8 | GO:0003402 | planar cell polarity pathway involved in axis elongation(GO:0003402) |
| 0.1 | 0.1 | GO:0015747 | urate transport(GO:0015747) |
| 0.1 | 2.5 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) |
| 0.1 | 0.6 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.1 | 1.6 | GO:0021670 | lateral ventricle development(GO:0021670) |
| 0.1 | 0.2 | GO:1902769 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 0.1 | 0.5 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
| 0.1 | 0.2 | GO:1990451 | cellular stress response to acidic pH(GO:1990451) |
| 0.1 | 0.6 | GO:0097026 | dendritic cell dendrite assembly(GO:0097026) |
| 0.1 | 0.2 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
| 0.1 | 0.2 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 0.1 | 2.0 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
| 0.1 | 0.4 | GO:0035022 | positive regulation of Rac protein signal transduction(GO:0035022) |
| 0.1 | 1.1 | GO:0008595 | tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) |
| 0.1 | 0.5 | GO:0060160 | negative regulation of dopamine receptor signaling pathway(GO:0060160) |
| 0.1 | 0.7 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
| 0.1 | 0.2 | GO:0061026 | cardiac muscle tissue regeneration(GO:0061026) |
| 0.1 | 0.8 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 1.4 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.1 | 0.2 | GO:0021524 | visceral motor neuron differentiation(GO:0021524) |
| 0.1 | 0.1 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.1 | 2.0 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.1 | 1.1 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
| 0.1 | 0.3 | GO:2000691 | negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691) |
| 0.1 | 0.2 | GO:0052250 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 0.1 | 0.4 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 0.1 | 0.6 | GO:0046618 | drug export(GO:0046618) |
| 0.1 | 1.3 | GO:0072189 | ureter development(GO:0072189) |
| 0.1 | 0.2 | GO:1904908 | negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908) |
| 0.1 | 0.7 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
| 0.1 | 0.1 | GO:1901859 | negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) |
| 0.1 | 0.4 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.1 | 0.8 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.1 | 0.4 | GO:0031860 | regulation of DNA-dependent DNA replication initiation(GO:0030174) telomeric 3' overhang formation(GO:0031860) |
| 0.1 | 0.2 | GO:0003331 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
| 0.1 | 1.0 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.1 | 0.5 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.1 | 1.2 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.1 | 0.2 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) |
| 0.1 | 0.8 | GO:0010578 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
| 0.1 | 0.7 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.1 | 0.4 | GO:0009441 | glycolate metabolic process(GO:0009441) |
| 0.1 | 0.2 | GO:1902688 | regulation of NAD metabolic process(GO:1902688) |
| 0.0 | 0.1 | GO:1902256 | apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) |
| 0.0 | 0.1 | GO:0061727 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.0 | 0.1 | GO:0070662 | mast cell proliferation(GO:0070662) |
| 0.0 | 0.0 | GO:0019184 | nonribosomal peptide biosynthetic process(GO:0019184) |
| 0.0 | 0.5 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.0 | 0.0 | GO:0010840 | regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746) |
| 0.0 | 0.7 | GO:1902224 | ketone body metabolic process(GO:1902224) |
| 0.0 | 0.1 | GO:0031247 | actin rod assembly(GO:0031247) |
| 0.0 | 0.3 | GO:0050916 | sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917) |
| 0.0 | 0.3 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.0 | 0.1 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 0.0 | 0.1 | GO:0001983 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994) positive regulation of the force of heart contraction by chemical signal(GO:0003099) |
| 0.0 | 0.2 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.0 | 1.1 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.0 | 0.2 | GO:0015911 | regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) plasma membrane long-chain fatty acid transport(GO:0015911) |
| 0.0 | 0.4 | GO:0021847 | ventricular zone neuroblast division(GO:0021847) |
| 0.0 | 0.3 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) |
| 0.0 | 0.9 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
| 0.0 | 0.3 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 0.0 | 0.2 | GO:0010958 | regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467) |
| 0.0 | 0.0 | GO:1901979 | regulation of inward rectifier potassium channel activity(GO:1901979) |
| 0.0 | 0.1 | GO:0036304 | umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027) |
| 0.0 | 0.2 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.0 | 0.3 | GO:0032431 | diacylglycerol biosynthetic process(GO:0006651) activation of phospholipase A2 activity(GO:0032431) |
| 0.0 | 1.5 | GO:0030220 | platelet formation(GO:0030220) |
| 0.0 | 0.9 | GO:0070233 | negative regulation of T cell apoptotic process(GO:0070233) |
| 0.0 | 0.2 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.0 | 0.4 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.0 | 0.3 | GO:0061669 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.0 | 1.4 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 1.4 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.0 | 0.1 | GO:0034241 | macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) |
| 0.0 | 0.5 | GO:0070257 | positive regulation of mucus secretion(GO:0070257) |
| 0.0 | 0.4 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.0 | 1.3 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.0 | 0.9 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.0 | 0.1 | GO:0046878 | positive regulation of saliva secretion(GO:0046878) |
| 0.0 | 0.2 | GO:1903904 | negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107) |
| 0.0 | 0.5 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 0.1 | GO:0021764 | amygdala development(GO:0021764) |
| 0.0 | 0.2 | GO:0001692 | histamine metabolic process(GO:0001692) |
| 0.0 | 0.1 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 0.0 | 0.2 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.0 | 0.1 | GO:0043060 | meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311) |
| 0.0 | 0.1 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.0 | 0.9 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.0 | 0.1 | GO:1903015 | regulation of exo-alpha-sialidase activity(GO:1903015) |
| 0.0 | 0.3 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
| 0.0 | 0.4 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.0 | 0.1 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.0 | 0.1 | GO:0036233 | glycine import(GO:0036233) |
| 0.0 | 0.3 | GO:0030007 | cellular potassium ion homeostasis(GO:0030007) |
| 0.0 | 0.2 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
| 0.0 | 0.1 | GO:0021898 | commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) regulation of amacrine cell differentiation(GO:1902869) |
| 0.0 | 0.1 | GO:0002331 | pre-B cell allelic exclusion(GO:0002331) |
| 0.0 | 0.9 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083) |
| 0.0 | 0.2 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.0 | 0.1 | GO:0042427 | serotonin biosynthetic process(GO:0042427) |
| 0.0 | 0.5 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.0 | 0.6 | GO:0009756 | carbohydrate mediated signaling(GO:0009756) |
| 0.0 | 0.2 | GO:0035973 | aggrephagy(GO:0035973) |
| 0.0 | 1.9 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.2 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 0.0 | 0.1 | GO:0072709 | response to sorbitol(GO:0072708) cellular response to sorbitol(GO:0072709) |
| 0.0 | 0.2 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.0 | 0.5 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.0 | 0.3 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.0 | 0.1 | GO:0051958 | methotrexate transport(GO:0051958) |
| 0.0 | 0.2 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.0 | 0.2 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.0 | 0.1 | GO:0033499 | galactose catabolic process via UDP-galactose(GO:0033499) |
| 0.0 | 0.1 | GO:1903259 | exon-exon junction complex disassembly(GO:1903259) |
| 0.0 | 0.2 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 0.0 | 0.1 | GO:1900133 | regulation of renin secretion into blood stream(GO:1900133) |
| 0.0 | 0.3 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.0 | 0.2 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.0 | 0.0 | GO:0060809 | mesodermal to mesenchymal transition involved in gastrulation(GO:0060809) |
| 0.0 | 0.1 | GO:0061011 | hepatic duct development(GO:0061011) |
| 0.0 | 0.3 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
| 0.0 | 0.4 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.0 | 0.5 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.2 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 0.1 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.0 | 0.2 | GO:0097186 | amelogenesis(GO:0097186) |
| 0.0 | 0.2 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.0 | 0.3 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 0.0 | 0.2 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.0 | 0.3 | GO:0001832 | blastocyst growth(GO:0001832) |
| 0.0 | 0.5 | GO:0035640 | exploration behavior(GO:0035640) |
| 0.0 | 1.8 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.2 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.0 | 0.1 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.0 | 0.1 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
| 0.0 | 0.5 | GO:0010719 | negative regulation of epithelial to mesenchymal transition(GO:0010719) |
| 0.0 | 0.2 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.0 | 0.1 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.0 | 0.1 | GO:1902748 | melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748) |
| 0.0 | 0.2 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.0 | 0.1 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 0.0 | 0.2 | GO:0098719 | sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 0.1 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.0 | 0.1 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.0 | 1.0 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.0 | 0.1 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) |
| 0.0 | 0.1 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.0 | 0.6 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.6 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.0 | 0.5 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 0.2 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.0 | 0.2 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.0 | 0.2 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.0 | 0.1 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.0 | 0.1 | GO:0045348 | positive regulation of MHC class II biosynthetic process(GO:0045348) |
| 0.0 | 0.2 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 0.0 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 0.0 | 0.0 | GO:0032430 | positive regulation of phospholipase A2 activity(GO:0032430) |
| 0.0 | 0.4 | GO:0034505 | tooth mineralization(GO:0034505) |
| 0.0 | 0.2 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.0 | 1.5 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.0 | GO:0048022 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670) |
| 0.0 | 0.4 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 0.1 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
| 0.0 | 0.0 | GO:0002304 | gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305) |
| 0.0 | 0.2 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 0.0 | GO:0071418 | cellular response to amine stimulus(GO:0071418) |
| 0.0 | 0.1 | GO:0035308 | negative regulation of protein dephosphorylation(GO:0035308) |
| 0.0 | 0.1 | GO:1904798 | positive regulation of core promoter binding(GO:1904798) |
| 0.0 | 0.1 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.0 | 0.1 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 0.0 | 0.1 | GO:0060023 | soft palate development(GO:0060023) |
| 0.0 | 1.0 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.0 | 0.0 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
| 0.0 | 0.1 | GO:0034285 | response to sucrose(GO:0009744) response to disaccharide(GO:0034285) |
| 0.0 | 0.1 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.0 | 0.1 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.0 | 0.2 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.0 | 0.0 | GO:1904386 | response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.0 | GO:0097224 | sperm connecting piece(GO:0097224) |
| 0.6 | 4.2 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.3 | 1.3 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.3 | 1.8 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.2 | 0.6 | GO:0060187 | cell pole(GO:0060187) |
| 0.2 | 1.5 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.1 | 1.6 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.1 | 0.6 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.1 | 0.3 | GO:1990716 | axonemal central apparatus(GO:1990716) |
| 0.1 | 1.7 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 0.3 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.1 | 0.5 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.1 | 0.4 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.1 | 0.8 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.1 | 1.5 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.1 | 0.9 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 1.1 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.1 | 0.8 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 1.0 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 0.2 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 0.0 | 0.2 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.0 | 0.1 | GO:0043159 | cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159) |
| 0.0 | 0.3 | GO:0002177 | manchette(GO:0002177) |
| 0.0 | 1.5 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.8 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.0 | 0.3 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.0 | 0.3 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.0 | 0.9 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.8 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 0.4 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.0 | 0.1 | GO:0034657 | GID complex(GO:0034657) |
| 0.0 | 0.4 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 0.4 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 0.8 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.8 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 3.1 | GO:0005930 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 0.3 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.0 | 3.6 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.4 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 1.2 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 0.3 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 0.9 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.0 | 0.3 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.1 | GO:0032798 | Swi5-Sfr1 complex(GO:0032798) |
| 0.0 | 0.1 | GO:0005592 | collagen type XI trimer(GO:0005592) |
| 0.0 | 0.6 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.0 | 0.2 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 0.1 | GO:0033063 | DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.0 | 0.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 0.0 | GO:0060342 | photoreceptor inner segment membrane(GO:0060342) |
| 0.0 | 0.1 | GO:0032302 | MutSbeta complex(GO:0032302) |
| 0.0 | 0.3 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.0 | 0.1 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.0 | 0.2 | GO:0060091 | kinocilium(GO:0060091) |
| 0.0 | 0.6 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 0.2 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 0.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.6 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 0.3 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.0 | 0.1 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 0.4 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.1 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.0 | 0.3 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 0.1 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.0 | 2.5 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 0.3 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.0 | 0.5 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 2.1 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.6 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.4 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.2 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 0.0 | 0.0 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.0 | 0.2 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.6 | GO:0031862 | prostanoid receptor binding(GO:0031862) |
| 0.4 | 1.6 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 0.3 | 1.0 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.3 | 0.8 | GO:0035248 | alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248) |
| 0.2 | 1.0 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.2 | 0.9 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.2 | 0.7 | GO:0019166 | 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.2 | 1.1 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
| 0.2 | 2.0 | GO:0032027 | myosin light chain binding(GO:0032027) |
| 0.2 | 0.9 | GO:0031750 | D3 dopamine receptor binding(GO:0031750) |
| 0.2 | 3.5 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.2 | 0.5 | GO:0090555 | phosphatidylethanolamine-translocating ATPase activity(GO:0090555) |
| 0.2 | 0.5 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.1 | 0.4 | GO:0003973 | (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854) |
| 0.1 | 0.7 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.1 | 0.9 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.1 | 0.8 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
| 0.1 | 1.5 | GO:0019864 | IgG binding(GO:0019864) |
| 0.1 | 0.7 | GO:0015307 | drug:proton antiporter activity(GO:0015307) |
| 0.1 | 1.3 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.1 | 4.3 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 0.3 | GO:0005148 | prolactin receptor binding(GO:0005148) |
| 0.1 | 0.4 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
| 0.1 | 0.6 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.1 | 0.8 | GO:0030345 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.1 | 1.7 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.1 | 0.5 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 0.1 | 0.3 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.1 | 1.5 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.1 | 1.7 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.1 | 0.4 | GO:0015087 | cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.1 | 0.4 | GO:0004167 | dopachrome isomerase activity(GO:0004167) |
| 0.1 | 1.1 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.1 | 1.1 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.1 | 1.0 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.1 | 0.3 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.1 | 0.8 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.1 | 1.7 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 0.2 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.1 | 1.7 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.1 | 1.2 | GO:0043495 | protein anchor(GO:0043495) |
| 0.1 | 0.2 | GO:0004419 | hydroxymethylglutaryl-CoA lyase activity(GO:0004419) |
| 0.1 | 0.9 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
| 0.1 | 1.9 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.0 | 0.1 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.0 | 0.4 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.0 | 0.1 | GO:0019150 | D-ribulokinase activity(GO:0019150) |
| 0.0 | 0.4 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 0.0 | 0.1 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.0 | 0.2 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.0 | 0.3 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.0 | 0.1 | GO:0008431 | vitamin E binding(GO:0008431) |
| 0.0 | 0.1 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
| 0.0 | 1.5 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 0.4 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.0 | 0.2 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.0 | 0.1 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
| 0.0 | 2.9 | GO:0008374 | O-acyltransferase activity(GO:0008374) |
| 0.0 | 0.2 | GO:0033265 | acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265) |
| 0.0 | 0.5 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.0 | 1.7 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.2 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.0 | 0.2 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.0 | 0.1 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.0 | 0.1 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.0 | 0.2 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.0 | 0.1 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.0 | 0.3 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.0 | 0.2 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.0 | 0.1 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.0 | 0.3 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.0 | 0.3 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.0 | 0.2 | GO:0000285 | 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) |
| 0.0 | 1.2 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.0 | 0.1 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 0.0 | 0.2 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.0 | 0.1 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682) |
| 0.0 | 0.1 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 0.0 | 0.1 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.0 | 0.1 | GO:0097363 | protein O-GlcNAc transferase activity(GO:0097363) |
| 0.0 | 0.1 | GO:0005415 | nucleoside:sodium symporter activity(GO:0005415) |
| 0.0 | 0.1 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) |
| 0.0 | 0.1 | GO:0031783 | corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) |
| 0.0 | 0.1 | GO:0015350 | methotrexate transporter activity(GO:0015350) |
| 0.0 | 0.2 | GO:0004935 | adrenergic receptor activity(GO:0004935) |
| 0.0 | 0.1 | GO:0004583 | dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583) |
| 0.0 | 0.5 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 0.1 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 0.0 | 0.6 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.1 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.0 | 0.1 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.0 | 0.1 | GO:0004558 | alpha-1,4-glucosidase activity(GO:0004558) |
| 0.0 | 0.1 | GO:0052795 | exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
| 0.0 | 0.1 | GO:0003860 | 3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860) |
| 0.0 | 0.5 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.0 | 0.3 | GO:0032393 | MHC class I receptor activity(GO:0032393) |
| 0.0 | 0.2 | GO:0022821 | potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821) |
| 0.0 | 0.2 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.0 | 0.0 | GO:0004339 | glucan 1,4-alpha-glucosidase activity(GO:0004339) |
| 0.0 | 0.1 | GO:0000406 | double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181) |
| 0.0 | 0.1 | GO:0071553 | uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553) |
| 0.0 | 1.2 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.1 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) |
| 0.0 | 0.3 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 0.1 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.0 | 0.5 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.7 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.0 | 0.1 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
| 0.0 | 0.1 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.0 | 0.1 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.0 | 0.8 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.2 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 0.1 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.0 | 0.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.1 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.0 | 0.1 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
| 0.0 | 0.1 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.0 | 0.1 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.0 | 0.1 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.0 | 0.0 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
| 0.0 | 0.1 | GO:0005534 | galactose binding(GO:0005534) |
| 0.0 | 0.0 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 0.0 | 0.2 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.0 | 0.8 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 0.1 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.0 | 0.0 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 0.0 | 0.3 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 1.0 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.1 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 0.1 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.0 | 0.0 | GO:0015222 | serotonin transmembrane transporter activity(GO:0015222) |
| 0.0 | 0.0 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 0.0 | 0.8 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.0 | 0.3 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.0 | 0.1 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.0 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.0 | 0.2 | GO:0005522 | profilin binding(GO:0005522) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 2.1 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 2.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.8 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.2 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 1.7 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 0.5 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 0.7 | ST ADRENERGIC | Adrenergic Pathway |
| 0.0 | 1.0 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.8 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 4.0 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.2 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 4.2 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.2 | 0.6 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 3.6 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 1.4 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.1 | 0.6 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 0.2 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 0.7 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.0 | 0.7 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.0 | 1.0 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.0 | 1.9 | REACTOME DOWNSTREAM TCR SIGNALING | Genes involved in Downstream TCR signaling |
| 0.0 | 1.3 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.0 | 1.2 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 0.4 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.7 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.5 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.6 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 1.0 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.5 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.0 | 0.6 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.1 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 0.5 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.5 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 1.3 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.5 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.7 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.7 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.5 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.7 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 0.2 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 0.4 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.2 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.0 | 0.2 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 0.4 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 1.0 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.5 | REACTOME CELL CELL JUNCTION ORGANIZATION | Genes involved in Cell-cell junction organization |