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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for MSX2

Z-value: 0.49

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Transcription factors associated with MSX2

Gene Symbol Gene ID Gene Info
MSX2
ENSG00000120149.9 MSX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSX2hg38_v1_chr5_+_174724549_1747246070.212.6e-01Click!

Activity profile of MSX2 motif

Sorted Z-values of MSX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_-_56392131 1.66 ENST00000422322.5
ENST00000371356.6
ENST00000451915.1
ENST00000347343.6
ENST00000395911.5
ENST00000395915.8
ENST00000395907.5
ENST00000441357.5
ENST00000456249.5
ENST00000420474.5
ENST00000395914.5
ENST00000312783.10
ENST00000395913.7
AURKA
aurora kinase A
chr16_-_46621345 1.65 ENST00000303383.8
SHCBP1
SHC binding and spindle associated 1
chr12_-_119877300 1.48 ENST00000392521.7
CIT
citron rho-interacting serine/threonine kinase
chr12_-_119877270 1.48 ENST00000261833.11
ENST00000612548.4
CIT
citron rho-interacting serine/threonine kinase
chr1_-_197146688 0.99 ENST00000294732.11
ASPM
assembly factor for spindle microtubules
chr13_+_108629605 0.91 ENST00000457511.7
MYO16
myosin XVI
chr12_+_53268289 0.91 ENST00000257934.9
ESPL1
extra spindle pole bodies like 1, separase
chr11_+_33039996 0.90 ENST00000432887.5
ENST00000528898.1
ENST00000531632.6
TCP11L1
t-complex 11 like 1
chr12_+_107318395 0.80 ENST00000420571.6
ENST00000280758.10
BTBD11
BTB domain containing 11
chr17_-_40417873 0.76 ENST00000423485.6
TOP2A
DNA topoisomerase II alpha
chr9_+_78297143 0.75 ENST00000347159.6
PSAT1
phosphoserine aminotransferase 1
chr1_-_197146620 0.67 ENST00000367409.9
ENST00000680265.1
ASPM
assembly factor for spindle microtubules
chr2_-_55296361 0.65 ENST00000647547.1
CCDC88A
coiled-coil domain containing 88A
chr6_+_130018565 0.64 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL3
L3MBTL histone methyl-lysine binding protein 3
chr2_-_55419565 0.63 ENST00000647341.1
ENST00000647401.1
ENST00000336838.10
ENST00000621814.4
ENST00000644033.1
ENST00000645477.1
ENST00000647517.1
CCDC88A
coiled-coil domain containing 88A
chr2_-_55419821 0.63 ENST00000644630.1
ENST00000471947.2
ENST00000436346.7
ENST00000642200.1
ENST00000413716.7
ENST00000263630.13
ENST00000645072.1
CCDC88A
coiled-coil domain containing 88A
chr9_+_78297117 0.61 ENST00000376588.4
PSAT1
phosphoserine aminotransferase 1
chr10_-_97687191 0.54 ENST00000370626.4
AVPI1
arginine vasopressin induced 1
chr1_-_93585071 0.50 ENST00000539242.5
BCAR3
BCAR3 adaptor protein, NSP family member
chr12_+_8950036 0.48 ENST00000539240.5
KLRG1
killer cell lectin like receptor G1
chr6_-_111606260 0.45 ENST00000340026.10
TRAF3IP2
TRAF3 interacting protein 2
chr19_+_42313298 0.43 ENST00000301204.8
ENST00000673205.1
TMEM145
transmembrane protein 145
chr6_+_31739948 0.42 ENST00000375755.8
ENST00000425703.5
ENST00000375750.9
ENST00000375703.7
ENST00000375740.7
MSH5
mutS homolog 5
chr12_+_119668109 0.41 ENST00000229328.10
ENST00000630317.1
PRKAB1
protein kinase AMP-activated non-catalytic subunit beta 1
chr19_+_41363989 0.39 ENST00000413014.6
TMEM91
transmembrane protein 91
chr6_+_106360668 0.38 ENST00000633556.3
CRYBG1
crystallin beta-gamma domain containing 1
chr14_+_32329341 0.38 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
AKAP6
A-kinase anchoring protein 6
chr10_-_103351133 0.37 ENST00000369847.4
PCGF6
polycomb group ring finger 6
chr12_-_9869345 0.36 ENST00000228438.3
CLEC2B
C-type lectin domain family 2 member B
chr6_+_159761991 0.36 ENST00000367048.5
ACAT2
acetyl-CoA acetyltransferase 2
chr10_-_103351074 0.36 ENST00000337211.8
PCGF6
polycomb group ring finger 6
chr19_+_42313374 0.35 ENST00000598766.1
ENST00000673187.1
TMEM145
transmembrane protein 145
chr11_-_69819410 0.34 ENST00000334134.4
FGF3
fibroblast growth factor 3
chr9_+_121567057 0.34 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2IP
DAB2 interacting protein
chrX_+_54920796 0.30 ENST00000442098.5
ENST00000430420.5
ENST00000453081.5
ENST00000319167.12
ENST00000622017.4
ENST00000375022.8
ENST00000399736.5
ENST00000440072.5
ENST00000173898.12
ENST00000431115.5
ENST00000440759.5
ENST00000375041.6
TRO
trophinin
chr5_+_96662046 0.30 ENST00000338252.7
ENST00000508830.5
CAST
calpastatin
chr11_-_7941708 0.30 ENST00000642047.1
OR10A3
olfactory receptor family 10 subfamily A member 3
chr3_-_48635426 0.29 ENST00000455886.6
ENST00000431739.5
ENST00000426599.1
ENST00000383733.7
ENST00000395550.7
ENST00000420764.6
ENST00000337000.12
SLC26A6
solute carrier family 26 member 6
chr11_-_122116215 0.29 ENST00000560104.2
BLID
BH3-like motif containing, cell death inducer
chr20_-_52105644 0.29 ENST00000371523.8
ZFP64
ZFP64 zinc finger protein
chr11_-_13496018 0.27 ENST00000529816.1
PTH
parathyroid hormone
chr16_+_69424634 0.25 ENST00000515314.6
ENST00000561792.6
ENST00000568237.1
CYB5B
cytochrome b5 type B
chr1_-_68232539 0.24 ENST00000370976.7
ENST00000354777.6
WLS
Wnt ligand secretion mediator
chr5_+_66958870 0.23 ENST00000405643.5
ENST00000407621.1
ENST00000432426.5
MAST4
microtubule associated serine/threonine kinase family member 4
chr6_+_25652272 0.23 ENST00000334979.6
SCGN
secretagogin, EF-hand calcium binding protein
chr4_-_108762964 0.23 ENST00000512646.5
ENST00000411864.6
ENST00000296486.8
ENST00000510706.5
ETNPPL
ethanolamine-phosphate phospho-lyase
chr10_-_97445850 0.21 ENST00000477692.6
ENST00000485122.6
ENST00000370886.9
ENST00000370885.8
ENST00000370902.8
ENST00000370884.5
EXOSC1
exosome component 1
chr10_+_123154364 0.20 ENST00000368859.6
ENST00000368865.9
BUB3
BUB3 mitotic checkpoint protein
chr5_-_149379286 0.20 ENST00000261796.4
IL17B
interleukin 17B
chr3_-_151316795 0.20 ENST00000260843.5
GPR87
G protein-coupled receptor 87
chr4_+_70721953 0.19 ENST00000381006.8
ENST00000226328.8
RUFY3
RUN and FYVE domain containing 3
chr11_-_13495984 0.19 ENST00000282091.6
PTH
parathyroid hormone
chr6_+_27810041 0.19 ENST00000369163.3
H3C10
H3 clustered histone 10
chrX_+_89921903 0.19 ENST00000283891.6
ENST00000561129.2
TGIF2LX
TGFB induced factor homeobox 2 like X-linked
chr5_+_96662314 0.18 ENST00000674702.1
CAST
calpastatin
chr9_+_34646654 0.18 ENST00000378842.8
GALT
galactose-1-phosphate uridylyltransferase
chr9_+_34646589 0.17 ENST00000450095.6
GALT
galactose-1-phosphate uridylyltransferase
chr1_+_151762899 0.17 ENST00000635322.1
ENST00000321531.10
OAZ3
ornithine decarboxylase antizyme 3
chr10_+_84194527 0.17 ENST00000623527.4
CDHR1
cadherin related family member 1
chr5_+_96662214 0.17 ENST00000395812.6
CAST
calpastatin
chr3_-_142029108 0.17 ENST00000497579.5
TFDP2
transcription factor Dp-2
chr5_+_96662366 0.17 ENST00000675179.1
ENST00000421689.6
ENST00000674984.1
ENST00000512620.5
CAST
calpastatin
chr14_-_23035223 0.16 ENST00000425762.2
PSMB5
proteasome 20S subunit beta 5
chr20_+_56392607 0.16 ENST00000217109.9
ENST00000452950.1
CSTF1
cleavage stimulation factor subunit 1
chr12_-_10802627 0.15 ENST00000240687.2
TAS2R7
taste 2 receptor member 7
chrX_+_115593570 0.14 ENST00000539310.5
PLS3
plastin 3
chr8_-_42768602 0.13 ENST00000534622.5
CHRNA6
cholinergic receptor nicotinic alpha 6 subunit
chr8_-_33567118 0.13 ENST00000256257.2
RNF122
ring finger protein 122
chr1_-_151992571 0.13 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr2_+_89913982 0.13 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr14_+_22202561 0.12 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr13_+_48037692 0.12 ENST00000258662.3
NUDT15
nudix hydrolase 15
chr19_+_4007714 0.12 ENST00000262971.3
PIAS4
protein inhibitor of activated STAT 4
chr15_+_40953463 0.12 ENST00000617768.5
CHAC1
ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr6_+_30720335 0.12 ENST00000327892.13
TUBB
tubulin beta class I
chr12_+_28257195 0.11 ENST00000381259.5
CCDC91
coiled-coil domain containing 91
chr7_+_99828010 0.11 ENST00000631161.2
ENST00000354829.7
ENST00000342499.8
ENST00000417625.5
ENST00000415413.5
ENST00000444905.5
ENST00000222382.5
ENST00000312017.9
CYP3A43
cytochrome P450 family 3 subfamily A member 43
chr8_+_2045037 0.11 ENST00000262113.9
MYOM2
myomesin 2
chr1_-_47314089 0.11 ENST00000360380.7
ENST00000371877.8
ENST00000447475.7
STIL
STIL centriolar assembly protein
chr1_-_68232514 0.10 ENST00000262348.9
ENST00000370973.2
ENST00000370971.1
WLS
Wnt ligand secretion mediator
chr19_+_15082211 0.10 ENST00000641398.1
OR1I1
olfactory receptor family 1 subfamily I member 1
chr9_-_4666495 0.10 ENST00000475086.5
SPATA6L
spermatogenesis associated 6 like
chr16_+_69311339 0.10 ENST00000254950.13
VPS4A
vacuolar protein sorting 4 homolog A
chr8_+_2045058 0.10 ENST00000523438.1
MYOM2
myomesin 2
chr6_-_111605859 0.10 ENST00000651359.1
ENST00000650859.1
ENST00000359831.8
ENST00000368761.11
TRAF3IP2
TRAF3 interacting protein 2
chr3_-_120285215 0.10 ENST00000464295.6
GPR156
G protein-coupled receptor 156
chr19_-_45782479 0.10 ENST00000447742.6
ENST00000354227.9
ENST00000291270.9
ENST00000683086.1
ENST00000343373.10
DMPK
DM1 protein kinase
chr7_-_88795732 0.10 ENST00000297203.3
TEX47
testis expressed 47
chr10_+_123154768 0.09 ENST00000407911.2
BUB3
BUB3 mitotic checkpoint protein
chrX_+_91434829 0.09 ENST00000312600.4
PABPC5
poly(A) binding protein cytoplasmic 5
chrX_-_21658324 0.08 ENST00000379499.3
KLHL34
kelch like family member 34
chr12_-_95003666 0.08 ENST00000327772.7
ENST00000547157.1
ENST00000684171.1
ENST00000547986.5
NDUFA12
NADH:ubiquinone oxidoreductase subunit A12
chr5_+_141417641 0.08 ENST00000612073.1
PCDHGB7
protocadherin gamma subfamily B, 7
chr1_-_151790475 0.08 ENST00000368825.7
ENST00000368823.5
ENST00000368824.8
ENST00000458431.6
ENST00000368827.10
ENST00000440583.6
TDRKH
tudor and KH domain containing
chr2_-_89268506 0.08 ENST00000473726.1
IGKV1-33
immunoglobulin kappa variable 1-33
chr1_+_175067831 0.08 ENST00000239462.9
TNN
tenascin N
chr10_+_97446194 0.07 ENST00000370846.8
ENST00000352634.8
ENST00000353979.7
ENST00000370842.6
ENST00000345745.9
ZDHHC16
zinc finger DHHC-type palmitoyltransferase 16
chr11_+_108665045 0.07 ENST00000322536.8
DDX10
DEAD-box helicase 10
chr14_-_52069039 0.07 ENST00000216286.10
NID2
nidogen 2
chr9_-_4666347 0.07 ENST00000381890.9
ENST00000682582.1
SPATA6L
spermatogenesis associated 6 like
chr6_-_116545658 0.07 ENST00000368602.4
TRAPPC3L
trafficking protein particle complex 3 like
chr14_+_32329256 0.07 ENST00000280979.9
AKAP6
A-kinase anchoring protein 6
chr11_-_72112669 0.06 ENST00000545944.5
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr10_+_97446137 0.06 ENST00000370854.7
ENST00000393760.6
ENST00000414567.5
ZDHHC16
zinc finger DHHC-type palmitoyltransferase 16
chr11_-_72112750 0.06 ENST00000545680.5
ENST00000543587.5
ENST00000538393.5
ENST00000535234.5
ENST00000227618.8
ENST00000535503.5
ANAPC15
anaphase promoting complex subunit 15
chr4_-_46124046 0.06 ENST00000295452.5
GABRG1
gamma-aminobutyric acid type A receptor subunit gamma1
chr5_+_141417659 0.06 ENST00000398594.4
PCDHGB7
protocadherin gamma subfamily B, 7
chr11_-_72112068 0.06 ENST00000537644.5
ENST00000538919.5
ENST00000539395.1
ENST00000542531.5
ANAPC15
anaphase promoting complex subunit 15
chr14_-_52069228 0.06 ENST00000617139.4
NID2
nidogen 2
chr1_-_21050952 0.06 ENST00000264211.12
EIF4G3
eukaryotic translation initiation factor 4 gamma 3
chr1_-_153922901 0.06 ENST00000634401.1
ENST00000368655.5
GATAD2B
GATA zinc finger domain containing 2B
chr10_-_54801221 0.06 ENST00000644397.2
ENST00000395445.6
ENST00000613657.5
ENST00000320301.11
PCDH15
protocadherin related 15
chr8_-_12755457 0.06 ENST00000398246.8
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr10_+_123154414 0.06 ENST00000368858.9
BUB3
BUB3 mitotic checkpoint protein
chr1_+_244352627 0.05 ENST00000366537.5
ENST00000308105.5
C1orf100
chromosome 1 open reading frame 100
chr17_-_31901658 0.05 ENST00000261708.9
UTP6
UTP6 small subunit processome component
chr7_-_100586119 0.05 ENST00000310300.11
LRCH4
leucine rich repeats and calponin homology domain containing 4
chr7_-_56106444 0.04 ENST00000395422.4
CHCHD2
coiled-coil-helix-coiled-coil-helix domain containing 2
chr17_+_76265332 0.04 ENST00000327490.8
ENST00000587913.1
UBALD2
UBA like domain containing 2
chr17_-_50707855 0.04 ENST00000285243.7
ANKRD40
ankyrin repeat domain 40
chr10_-_54801262 0.04 ENST00000373965.6
ENST00000616114.4
ENST00000621708.4
ENST00000495484.5
ENST00000395440.5
ENST00000395442.5
ENST00000617271.4
ENST00000395446.5
ENST00000409834.5
ENST00000361849.7
ENST00000373957.7
ENST00000395430.5
ENST00000395433.5
ENST00000437009.5
PCDH15
protocadherin related 15
chrX_+_114584037 0.04 ENST00000371951.5
ENST00000371950.3
ENST00000276198.6
HTR2C
5-hydroxytryptamine receptor 2C
chr8_+_9555900 0.04 ENST00000310430.11
ENST00000520408.5
ENST00000522110.1
TNKS
tankyrase
chr4_+_70195719 0.04 ENST00000683306.1
ODAM
odontogenic, ameloblast associated
chr19_-_19138442 0.04 ENST00000587583.6
ENST00000450333.6
ENST00000587096.5
ENST00000162044.14
ENST00000592369.1
ENST00000587915.1
TMEM161A
transmembrane protein 161A
chr1_+_174700413 0.03 ENST00000529145.6
ENST00000325589.9
RABGAP1L
RAB GTPase activating protein 1 like
chr10_-_54801179 0.03 ENST00000373955.5
PCDH15
protocadherin related 15
chr17_-_10469558 0.03 ENST00000255381.2
MYH4
myosin heavy chain 4
chr7_-_100119323 0.03 ENST00000523306.5
ENST00000344095.8
ENST00000417349.5
ENST00000493322.5
ENST00000520135.5
ENST00000460673.2
ENST00000453269.7
ENST00000452041.5
ENST00000452438.6
ENST00000451699.5
TAF6
TATA-box binding protein associated factor 6
chr19_+_17267376 0.03 ENST00000447614.6
ENST00000359435.8
ENST00000599474.5
ENST00000599057.5
ENST00000598188.6
ENST00000601043.5
BABAM1
BRISC and BRCA1 A complex member 1
chr12_-_53336342 0.02 ENST00000537210.2
ENST00000536324.4
SP7
Sp7 transcription factor
chr3_-_165078480 0.02 ENST00000264382.8
SI
sucrase-isomaltase
chr21_-_18403754 0.01 ENST00000284885.8
TMPRSS15
transmembrane serine protease 15
chr15_-_51243011 0.01 ENST00000405913.7
ENST00000559878.5
CYP19A1
cytochrome P450 family 19 subfamily A member 1
chr6_+_132538290 0.01 ENST00000434551.2
TAAR9
trace amine associated receptor 9
chr7_+_100612372 0.01 ENST00000493970.5
MOSPD3
motile sperm domain containing 3
chr19_+_17267469 0.00 ENST00000596335.5
ENST00000601436.5
ENST00000595632.5
BABAM1
BRISC and BRCA1 A complex member 1
chr1_+_202348727 0.00 ENST00000356764.6
PPP1R12B
protein phosphatase 1 regulatory subunit 12B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.5 1.4 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
0.4 1.7 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.3 1.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 0.9 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.3 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.5 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.7 GO:0019236 response to pheromone(GO:0019236)
0.1 0.3 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.8 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.2 GO:0015847 putrescine transport(GO:0015847)
0.1 0.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 3.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.8 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.4 GO:0035878 nail development(GO:0035878)
0.0 0.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 1.7 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.0 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.5 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 1.7 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.3 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 3.0 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.4 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 2.8 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 1.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.4 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 1.9 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.2 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.3 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.1 0.2 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 1.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 2.9 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.0 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.7 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 1.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination