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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NFATC4

Z-value: 1.03

Motif logo

Transcription factors associated with NFATC4

Gene Symbol Gene ID Gene Info
ENSG00000100968.14 NFATC4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC4hg38_v1_chr14_+_24368020_24368341-0.514.4e-03Click!

Activity profile of NFATC4 motif

Sorted Z-values of NFATC4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_+_96482982 7.07 ENST00000554706.1
adenylate kinase 7
chr2_+_98087160 6.59 ENST00000477737.6
von Willebrand factor A domain containing 3B
chr1_-_161367872 5.82 ENST00000367974.2
cilia and flagella associated protein 126
chr1_+_111346590 5.60 ENST00000369737.4
ENST00000369738.9
primary cilia formation
chr6_+_32439866 5.10 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr11_+_102047422 4.23 ENST00000434758.7
ENST00000526781.5
ENST00000534360.1
cilia and flagella associated protein 300
chr1_+_37556913 3.87 ENST00000296218.8
ENST00000652629.1
dynein axonemal light intermediate chain 1
chr7_+_30852273 3.71 ENST00000509504.2
novel protein, MINDY4 and AQP1 readthrough
chr1_-_74673786 3.63 ENST00000326665.10
glutamate rich 3
chr10_-_25062279 3.43 ENST00000615958.4
enkurin, TRPC channel interacting protein
chr1_-_150765735 3.34 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr10_-_114684612 3.28 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr14_+_75069577 3.17 ENST00000238686.8
zinc finger C2HC-type containing 1C
chr14_+_75069632 3.16 ENST00000439583.2
ENST00000554763.2
ENST00000524913.3
ENST00000525046.2
ENST00000674086.1
ENST00000526130.2
ENST00000674094.1
ENST00000532198.2
zinc finger C2HC-type containing 1C
chr12_-_71157992 3.07 ENST00000247829.8
tetraspanin 8
chr2_-_206765274 2.96 ENST00000454776.6
ENST00000449792.5
ENST00000374412.8
malate dehydrogenase 1B
chr12_-_71157872 2.95 ENST00000546561.2
tetraspanin 8
chr9_-_77648303 2.89 ENST00000341700.7
G protein subunit alpha 14
chr7_+_6754109 2.80 ENST00000403107.5
ENST00000404077.5
ENST00000435395.5
ENST00000418406.1
radial spoke head 10 homolog B2
chr11_-_62707581 2.75 ENST00000684475.1
ENST00000683296.1
ENST00000684067.1
ENST00000682223.1
BSCL2 lipid droplet biogenesis associated, seipin
chr16_+_57735723 2.71 ENST00000562592.5
ENST00000379661.8
ENST00000566726.5
katanin regulatory subunit B1
chr14_-_91946989 2.66 ENST00000556154.5
fibulin 5
chr4_-_99435134 2.66 ENST00000476959.5
ENST00000482593.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_-_62707413 2.65 ENST00000360796.10
ENST00000449636.6
BSCL2 lipid droplet biogenesis associated, seipin
chr14_-_91947383 2.57 ENST00000267620.14
fibulin 5
chr2_+_27014746 2.50 ENST00000648289.1
ENST00000458529.5
ENST00000402218.1
microtubule associated protein RP/EB family member 3
chr4_-_99435336 2.42 ENST00000437033.7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr7_-_120858066 2.42 ENST00000222747.8
tetraspanin 12
chr1_+_103571077 2.31 ENST00000610648.1
amylase alpha 2B
chr8_-_109648825 2.19 ENST00000533895.5
ENST00000446070.6
ENST00000528331.5
ENST00000526302.5
ENST00000408908.6
ENST00000433638.1
ENST00000524720.5
syntabulin
chr5_-_43412323 2.14 ENST00000361115.4
C-C motif chemokine ligand 28
chr3_-_112975018 2.12 ENST00000471858.5
ENST00000308611.8
ENST00000295863.4
CD200 receptor 1
chr8_-_109691590 1.99 ENST00000532779.5
ENST00000534578.5
syntabulin
chr2_-_158380960 1.96 ENST00000409187.5
coiled-coil domain containing 148
chr7_+_92057602 1.80 ENST00000491695.2
A-kinase anchoring protein 9
chr15_-_52295792 1.78 ENST00000261839.12
myosin VC
chr3_-_112974912 1.76 ENST00000440122.6
ENST00000490004.1
CD200 receptor 1
chr14_-_106470788 1.72 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr8_+_93754879 1.70 ENST00000453906.6
ENST00000683362.1
ENST00000682036.1
ENST00000453321.8
ENST00000409623.8
ENST00000520680.2
ENST00000521517.6
ENST00000452276.6
transmembrane protein 67
chr5_+_76403266 1.68 ENST00000274364.11
IQ motif containing GTPase activating protein 2
chr17_+_55266216 1.65 ENST00000573945.5
HLF transcription factor, PAR bZIP family member
chr5_+_140875299 1.62 ENST00000613593.1
ENST00000398631.3
protocadherin alpha 12
chr2_+_97713568 1.61 ENST00000264972.10
zeta chain of T cell receptor associated protein kinase 70
chr4_-_99435396 1.56 ENST00000209665.8
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_+_212608628 1.56 ENST00000613954.4
ENST00000341491.9
ENST00000366985.5
activating transcription factor 3
chr1_-_223364059 1.51 ENST00000343846.7
ENST00000484758.6
ENST00000344029.6
ENST00000366878.9
ENST00000494793.6
ENST00000681285.1
ENST00000680429.1
ENST00000681669.1
ENST00000681305.1
sushi domain containing 4
chr6_+_39793008 1.41 ENST00000398904.6
dishevelled associated activator of morphogenesis 2
chr1_+_61404076 1.40 ENST00000357977.5
nuclear factor I A
chr10_+_80078646 1.36 ENST00000372277.7
ENST00000613758.4
ENST00000372281.8
ENST00000372275.5
ENST00000372274.5
transmembrane protein 254
chr5_-_124745315 1.35 ENST00000306315.9
zinc finger protein 608
chr11_+_111918900 1.32 ENST00000278601.6
chromosome 11 open reading frame 52
chr12_-_49187369 1.31 ENST00000547939.6
tubulin alpha 1a
chr8_-_71362054 1.31 ENST00000340726.8
EYA transcriptional coactivator and phosphatase 1
chr5_-_124746630 1.30 ENST00000513986.2
zinc finger protein 608
chr17_-_41124178 1.30 ENST00000394014.2
keratin associated protein 4-12
chr14_+_20688756 1.30 ENST00000397990.5
ENST00000555597.1
angiogenin
ribonuclease A family member 4
chr7_-_120858303 1.27 ENST00000415871.5
ENST00000430985.1
tetraspanin 12
chr18_-_55351977 1.24 ENST00000643689.1
transcription factor 4
chr21_-_32813679 1.23 ENST00000487113.1
ENST00000382373.4
chromosome 21 open reading frame 62
chr12_-_49189053 1.22 ENST00000550767.6
ENST00000546918.1
ENST00000679733.1
ENST00000552924.2
ENST00000301071.12
tubulin alpha 1a
chr1_+_61082553 1.22 ENST00000403491.8
ENST00000371187.7
nuclear factor I A
chr8_-_71361860 1.21 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chr14_-_75069478 1.21 ENST00000555463.1
acylphosphatase 1
chr3_+_108602776 1.14 ENST00000497905.5
ENST00000463306.1
DAZ interacting zinc finger protein 3
chr12_-_39340963 1.13 ENST00000552961.5
kinesin family member 21A
chr22_-_39152622 1.12 ENST00000216133.10
chromobox 7
chr3_+_184337591 1.11 ENST00000383847.7
family with sequence similarity 131 member A
chr19_-_41363930 1.10 ENST00000675972.1
B9 domain containing 2
chr10_-_114684457 1.10 ENST00000392955.7
actin binding LIM protein 1
chr3_+_69763726 1.09 ENST00000448226.9
melanocyte inducing transcription factor
chr1_+_78649818 1.09 ENST00000370747.9
ENST00000438486.1
interferon induced protein 44
chr7_-_51316754 1.08 ENST00000632460.1
ENST00000441453.5
ENST00000648294.1
ENST00000265136.12
ENST00000395542.6
ENST00000395540.6
cordon-bleu WH2 repeat protein
chr17_+_81995434 1.07 ENST00000582355.6
ASPSCR1 tether for SLC2A4, UBX domain containing
chr1_-_56579555 1.07 ENST00000371250.4
phospholipid phosphatase 3
chr10_+_80079036 1.06 ENST00000372273.7
transmembrane protein 254
chr5_-_42811884 1.00 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr6_-_154356735 1.00 ENST00000367220.8
ENST00000265198.8
ENST00000520261.1
interaction protein for cytohesin exchange factors 1
chr8_+_85245451 0.99 ENST00000321764.4
carbonic anhydrase 13
chr1_+_148748774 0.97 ENST00000322209.5
nudix hydrolase 4B
chr6_+_39792298 0.94 ENST00000633794.1
ENST00000274867.9
dishevelled associated activator of morphogenesis 2
chr7_-_78771265 0.93 ENST00000630991.2
ENST00000629359.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_+_41538143 0.93 ENST00000503057.6
ENST00000511496.5
LIM and calponin homology domains 1
chr3_-_120647018 0.92 ENST00000475447.2
homogentisate 1,2-dioxygenase
chr14_+_88385714 0.91 ENST00000045347.11
spermatogenesis associated 7
chr6_-_15586006 0.90 ENST00000462989.6
dystrobrevin binding protein 1
chr9_-_20382461 0.90 ENST00000380321.5
ENST00000629733.3
MLLT3 super elongation complex subunit
chr3_-_149333407 0.90 ENST00000470080.5
transmembrane 4 L six family member 18
chr5_-_59430600 0.89 ENST00000636120.1
phosphodiesterase 4D
chr6_+_89562308 0.88 ENST00000522441.5
ankyrin repeat domain 6
chr5_+_43602648 0.87 ENST00000505678.6
ENST00000512422.5
ENST00000264663.9
ENST00000670904.1
ENST00000653251.1
nicotinamide nucleotide transhydrogenase
chr15_+_33968484 0.87 ENST00000383263.7
cholinergic receptor muscarinic 5
chr9_-_13165442 0.86 ENST00000542239.1
ENST00000538841.5
ENST00000433359.6
multiple PDZ domain crumbs cell polarity complex component
chr17_+_28506320 0.86 ENST00000579795.6
forkhead box N1
chr8_+_28890365 0.85 ENST00000519662.5
ENST00000558662.5
ENST00000287701.15
ENST00000523613.5
ENST00000560599.5
ENST00000397358.7
homeobox containing 1
chr4_-_1668905 0.85 ENST00000461064.5
family with sequence similarity 53 member A
chr7_-_64563063 0.83 ENST00000309683.11
zinc finger protein 680
chr14_-_21511290 0.83 ENST00000298717.9
methyltransferase like 3
chr12_-_89524734 0.83 ENST00000529983.3
polypeptide N-acetylgalactosaminyltransferase 4
chr3_-_122022122 0.82 ENST00000393631.5
ENST00000273691.7
ENST00000344209.10
immunoglobulin like domain containing receptor 1
chr1_-_173917281 0.81 ENST00000367698.4
serpin family C member 1
chr15_-_77420135 0.81 ENST00000560626.6
pseudopodium enriched atypical kinase 1
chr12_-_89656051 0.80 ENST00000261173.6
ATPase plasma membrane Ca2+ transporting 1
chr18_+_50967991 0.79 ENST00000588577.5
elaC ribonuclease Z 1
chr12_-_89656093 0.79 ENST00000359142.7
ATPase plasma membrane Ca2+ transporting 1
chr1_+_56645299 0.78 ENST00000371244.9
ENST00000610361.1
protein kinase AMP-activated catalytic subunit alpha 2
chr16_+_67347358 0.78 ENST00000563189.5
leucine rich repeat containing 36
chr8_-_56211257 0.75 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1 zinc finger
chr1_+_145964675 0.75 ENST00000369314.2
ENST00000369313.7
RNA polymerase III subunit GL
chr18_-_55423757 0.74 ENST00000675707.1
transcription factor 4
chr11_-_47578768 0.74 ENST00000525720.1
ENST00000531067.1
ENST00000533290.5
ENST00000529499.1
ENST00000529946.1
ENST00000526005.5
ENST00000395288.6
ENST00000430070.7
ENST00000534239.1
kelch repeat and BTB domain containing 4
chr2_-_174847015 0.73 ENST00000650938.1
chimerin 1
chr6_+_148342759 0.72 ENST00000367467.8
SAM and SH3 domain containing 1
chr16_+_67347391 0.72 ENST00000435835.3
leucine rich repeat containing 36
chr22_-_17258235 0.70 ENST00000649310.1
ENST00000649746.1
adenosine deaminase 2
chrX_+_130339941 0.70 ENST00000218197.9
solute carrier family 25 member 14
chr14_+_80955366 0.70 ENST00000342443.10
thyroid stimulating hormone receptor
chr17_+_50532713 0.69 ENST00000503690.5
ENST00000514874.5
ENST00000268933.8
epsin 3
chr1_-_151459471 0.68 ENST00000271715.7
pogo transposable element derived with ZNF domain
chr15_-_77420087 0.67 ENST00000564328.5
ENST00000682557.1
ENST00000558305.5
pseudopodium enriched atypical kinase 1
chr2_+_232697299 0.67 ENST00000476995.5
ENST00000427233.5
ENST00000629305.2
ENST00000428883.5
ENST00000456491.5
ENST00000409480.5
ENST00000492910.5
ENST00000464402.5
ENST00000490612.5
ENST00000475359.6
ENST00000421433.5
ENST00000425040.5
ENST00000430720.5
ENST00000409547.5
ENST00000373563.9
ENST00000423659.5
ENST00000409196.7
ENST00000488734.5
ENST00000409451.7
ENST00000429187.5
ENST00000440945.5
GRB10 interacting GYF protein 2
chr6_-_134174853 0.66 ENST00000475719.6
ENST00000367857.9
ENST00000237305.11
serum/glucocorticoid regulated kinase 1
chr14_+_80955650 0.66 ENST00000554263.5
ENST00000554435.1
thyroid stimulating hormone receptor
chr9_+_26956384 0.65 ENST00000518614.5
ENST00000380062.10
intraflagellar transport 74
chr14_+_75522427 0.64 ENST00000286639.8
basic leucine zipper ATF-like transcription factor
chr15_-_88546585 0.63 ENST00000649547.1
ENST00000558413.1
ENST00000564406.5
ENST00000268148.13
novel transcript
DET1 partner of COP1 E3 ubiquitin ligase
chrX_+_130339886 0.63 ENST00000543953.5
ENST00000612248.4
ENST00000424447.5
ENST00000545805.6
solute carrier family 25 member 14
chr18_+_50968027 0.63 ENST00000269466.8
ENST00000591429.1
elaC ribonuclease Z 1
chr11_-_96343170 0.62 ENST00000524717.6
mastermind like transcriptional coactivator 2
chr5_+_168291599 0.62 ENST00000265293.9
WW and C2 domain containing 1
chr7_-_105679089 0.62 ENST00000477775.5
ataxin 7 like 1
chr5_-_40755885 0.62 ENST00000636863.1
ENST00000637375.1
ENST00000337702.5
ENST00000636106.1
tetratricopeptide repeat domain 33
chr6_-_26056460 0.61 ENST00000343677.4
H1.2 linker histone, cluster member
chr12_+_109139397 0.61 ENST00000377854.9
ENST00000377848.7
acetyl-CoA carboxylase beta
chr4_-_145180496 0.61 ENST00000447906.8
OTU deubiquitinase 4
chr11_+_66466745 0.61 ENST00000349459.10
ENST00000320740.12
ENST00000524466.5
ENST00000526296.5
pellino E3 ubiquitin protein ligase family member 3
chr20_-_35529618 0.60 ENST00000246199.5
ENST00000424444.1
ENST00000374345.8
ENST00000444723.3
chromosome 20 open reading frame 173
chr1_+_164559173 0.60 ENST00000420696.7
PBX homeobox 1
chr3_+_98353854 0.58 ENST00000354924.2
olfactory receptor family 5 subfamily K member 4
chr12_-_49188811 0.58 ENST00000295766.9
tubulin alpha 1a
chr19_-_39245006 0.57 ENST00000413851.3
ENST00000613087.4
interferon lambda 3
chr2_-_174847525 0.57 ENST00000295497.12
ENST00000652036.1
ENST00000444394.6
ENST00000650731.1
chimerin 1
chr19_+_39268394 0.57 ENST00000331982.6
interferon lambda 2
chr5_-_135895834 0.56 ENST00000274520.2
interleukin 9
chr3_+_186842687 0.56 ENST00000444204.2
ENST00000320741.7
adiponectin, C1Q and collagen domain containing
chr9_+_89318492 0.55 ENST00000375807.8
ENST00000339901.8
SECIS binding protein 2
chr11_+_93330712 0.54 ENST00000298050.9
deuterosome assembly protein 1
chr3_-_94028582 0.54 ENST00000315099.3
syntaxin 19
chr11_+_31816266 0.54 ENST00000644607.1
ENST00000646221.1
ENST00000643671.1
ENST00000643931.1
ENST00000642614.1
ENST00000642818.1
ENST00000645848.1
ENST00000506388.2
ENST00000645824.1
ENST00000532942.5
PAX6 upstream antisense RNA
novel protein
chr19_-_55370455 0.53 ENST00000264563.7
ENST00000585513.1
ENST00000590625.5
interleukin 11
chrX_-_135344101 0.53 ENST00000370766.8
zinc finger protein 75D
chrX_+_10156960 0.53 ENST00000380833.9
chloride voltage-gated channel 4
chr17_-_62806632 0.53 ENST00000583803.1
ENST00000456609.6
membrane associated ring-CH-type finger 10
chr20_+_15196834 0.53 ENST00000402914.5
mono-ADP ribosylhydrolase 2
chr12_-_58920465 0.53 ENST00000320743.8
leucine rich repeats and immunoglobulin like domains 3
chr9_-_136439796 0.53 ENST00000676019.1
ENST00000371712.4
inositol polyphosphate-5-phosphatase E
chr12_-_100262356 0.52 ENST00000548313.5
DEP domain containing 4
chr4_-_107036302 0.52 ENST00000285311.8
dickkopf WNT signaling pathway inhibitor 2
chr2_+_86441341 0.52 ENST00000312912.10
ENST00000409064.5
lysine demethylase 3A
chr9_+_4679555 0.52 ENST00000381858.5
ENST00000381854.4
cell division cycle 37 like 1
chr1_+_160127672 0.51 ENST00000447527.1
ATPase Na+/K+ transporting subunit alpha 2
chr1_+_174877430 0.51 ENST00000392064.6
RAB GTPase activating protein 1 like
chr4_-_83334782 0.51 ENST00000681769.1
ENST00000513463.1
ENST00000311412.10
heparanase
chr1_-_85404494 0.51 ENST00000633113.1
dimethylarginine dimethylaminohydrolase 1
chr3_-_27722316 0.50 ENST00000449599.4
eomesodermin
chr12_-_9115907 0.50 ENST00000318602.12
alpha-2-macroglobulin
chrX_-_85379703 0.49 ENST00000373145.3
POF1B actin binding protein
chr2_-_190250503 0.49 ENST00000409820.2
ENST00000410045.5
3-hydroxyisobutyryl-CoA hydrolase
chr9_+_68780029 0.49 ENST00000394264.7
PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1
chr2_-_241637045 0.48 ENST00000407315.6
THAP domain containing 4
chr10_+_116590956 0.48 ENST00000358834.9
ENST00000528052.5
pancreatic lipase related protein 1
chr17_+_7888783 0.47 ENST00000330494.12
ENST00000358181.8
chromodomain helicase DNA binding protein 3
chr2_-_151973780 0.47 ENST00000637514.1
ENST00000636350.1
ENST00000434468.2
ENST00000637762.1
ENST00000637779.1
ENST00000637547.1
ENST00000636901.1
ENST00000397327.7
ENST00000636721.1
ENST00000636380.1
ENST00000637284.1
ENST00000636617.1
ENST00000636947.1
ENST00000638091.1
ENST00000636108.1
ENST00000638040.1
ENST00000636773.1
ENST00000637418.1
ENST00000637216.1
calcium voltage-gated channel auxiliary subunit beta 4
chr11_-_62689523 0.47 ENST00000317449.5
LRRN4 C-terminal like
chr6_-_158644709 0.47 ENST00000367089.8
dynein light chain Tctex-type 1
chr2_+_205683109 0.47 ENST00000357118.8
ENST00000272849.7
ENST00000412873.2
neuropilin 2
chr18_+_13218195 0.47 ENST00000679167.1
low density lipoprotein receptor class A domain containing 4
chr2_-_151973991 0.47 ENST00000534999.6
ENST00000637217.1
ENST00000360283.11
calcium voltage-gated channel auxiliary subunit beta 4
chr6_+_30327259 0.46 ENST00000376659.9
ENST00000428555.1
tripartite motif containing 39
chr12_-_7091873 0.46 ENST00000538050.5
ENST00000536053.6
complement C1r
chr5_+_173889337 0.46 ENST00000520867.5
ENST00000334035.9
cytoplasmic polyadenylation element binding protein 4
chr15_+_65621923 0.46 ENST00000339868.10
ENST00000261892.11
solute carrier family 24 member 1
chr3_-_52835011 0.45 ENST00000446157.3
musculoskeletal, embryonic nuclear protein 1
chr1_-_230868474 0.45 ENST00000366663.10
chromosome 1 open reading frame 198
chr2_-_178478499 0.45 ENST00000434643.6
FKBP prolyl isomerase 7
chr14_+_55611977 0.45 ENST00000395309.7
ENST00000413890.6
kinectin 1
chr4_+_81030700 0.44 ENST00000282701.4
bone morphogenetic protein 3
chr20_+_13008919 0.44 ENST00000399002.7
ENST00000434210.5
serine palmitoyltransferase long chain base subunit 3
chr6_+_127577168 0.44 ENST00000329722.8
chromosome 6 open reading frame 58
chr11_-_116792386 0.44 ENST00000433069.2
ENST00000542499.5
apolipoprotein A5
chr3_+_119597874 0.44 ENST00000488919.5
ENST00000273371.9
ENST00000495992.5
phospholipase A1 member A
chr11_+_6845683 0.43 ENST00000299454.5
olfactory receptor family 10 subfamily A member 5
chr21_+_41168142 0.43 ENST00000330333.11
beta-secretase 2
chr5_+_102755269 0.42 ENST00000304400.12
ENST00000455264.7
ENST00000684529.1
ENST00000438793.8
ENST00000682882.1
ENST00000682972.1
ENST00000348126.7
ENST00000512073.1
peptidylglycine alpha-amidating monooxygenase
chr15_-_37101205 0.42 ENST00000338564.9
ENST00000558313.5
ENST00000340545.9
Meis homeobox 2
chr18_+_58196736 0.41 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr14_+_75522531 0.41 ENST00000555504.1
basic leucine zipper ATF-like transcription factor
chr3_-_27722699 0.41 ENST00000461503.2
eomesodermin
chr9_-_13279407 0.40 ENST00000546205.5
multiple PDZ domain crumbs cell polarity complex component
chr12_+_67648737 0.40 ENST00000344096.4
ENST00000393555.3
dual specificity tyrosine phosphorylation regulated kinase 2
chr14_+_63852951 0.40 ENST00000357395.7
ENST00000358025.7
ENST00000344113.8
ENST00000341472.9
ENST00000555002.6
spectrin repeat containing nuclear envelope protein 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
1.7 6.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.1 3.3 GO:0034769 basement membrane disassembly(GO:0034769)
0.8 2.5 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.7 2.7 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.5 1.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.5 1.4 GO:0042779 tRNA 3'-trailer cleavage, endonucleolytic(GO:0034414) tRNA 3'-trailer cleavage(GO:0042779)
0.4 5.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 1.3 GO:1904588 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.3 0.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.3 0.9 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.3 2.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 1.6 GO:0043366 beta selection(GO:0043366)
0.3 2.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 2.9 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 3.0 GO:0006108 malate metabolic process(GO:0006108)
0.2 1.1 GO:0001757 somite specification(GO:0001757)
0.2 5.4 GO:0034389 lipid particle organization(GO:0034389)
0.2 1.6 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.2 0.8 GO:0018032 protein amidation(GO:0018032)
0.2 0.8 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.2 0.6 GO:0072249 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.2 1.3 GO:0032431 diacylglycerol biosynthetic process(GO:0006651) activation of phospholipase A2 activity(GO:0032431)
0.2 0.9 GO:0006740 NADPH regeneration(GO:0006740)
0.2 0.5 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.2 0.5 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.2 0.5 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 0.5 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.8 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1 0.5 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 1.8 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 1.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 1.0 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.6 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.3 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
0.1 6.5 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 1.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 0.7 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.6 GO:0002005 angiotensin catabolic process in blood(GO:0002005) angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.7 GO:1905066 arterial endothelial cell fate commitment(GO:0060844) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 1.7 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.1 0.3 GO:0036245 cellular response to menadione(GO:0036245)
0.1 0.6 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.3 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.1 GO:0045399 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401)
0.1 1.6 GO:0051382 kinetochore assembly(GO:0051382)
0.1 3.6 GO:0010842 retina layer formation(GO:0010842)
0.1 1.1 GO:0008354 germ cell migration(GO:0008354)
0.1 0.9 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.7 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.5 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.2 GO:0098904 pulmonary valve formation(GO:0003193) foramen ovale closure(GO:0035922) regulation of AV node cell action potential(GO:0098904) regulation of bundle of His cell action potential(GO:0098905)
0.1 0.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 2.3 GO:0072189 ureter development(GO:0072189)
0.1 5.8 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.7 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.6 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 1.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.3 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1 0.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.2 GO:0050822 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 0.8 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.2 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1 1.0 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.4 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.3 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.8 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.2 GO:1904045 cellular response to aldosterone(GO:1904045)
0.0 0.7 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.4 GO:0070054 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.0 0.8 GO:0006853 carnitine shuttle(GO:0006853) histone-serine phosphorylation(GO:0035404)
0.0 0.5 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.5 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 1.0 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.9 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.0 0.3 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 3.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.8 GO:0016180 snRNA processing(GO:0016180)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.5 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.1 GO:0002357 defense response to tumor cell(GO:0002357)
0.0 0.6 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:0061157 mRNA destabilization(GO:0061157)
0.0 2.7 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 1.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.4 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.6 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 4.9 GO:0044782 cilium organization(GO:0044782)
0.0 0.4 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 2.0 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.4 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 1.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.2 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 2.7 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 1.3 GO:0009060 aerobic respiration(GO:0009060)
0.0 1.0 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.4 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.0 GO:1904908 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.0 0.6 GO:0097503 sialylation(GO:0097503)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0089712 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.8 GO:0090277 positive regulation of peptide hormone secretion(GO:0090277)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)
0.0 0.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 1.6 GO:0007018 microtubule-based movement(GO:0007018)
0.0 1.4 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.1 GO:0070942 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.5 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.4 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.1 GO:0071953 elastic fiber(GO:0071953)
0.5 1.6 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.5 1.8 GO:0044307 dendritic branch(GO:0044307)
0.3 2.1 GO:0036021 endolysosome lumen(GO:0036021)
0.3 4.2 GO:0097433 dense body(GO:0097433)
0.3 5.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.9 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.2 1.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.2 0.8 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2 1.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 0.5 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 2.8 GO:0036038 MKS complex(GO:0036038)
0.1 1.1 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.8 GO:1990635 proximal dendrite(GO:1990635)
0.1 12.7 GO:0036064 ciliary basal body(GO:0036064)
0.1 1.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 2.9 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.8 GO:0061689 tricellular tight junction(GO:0061689)
0.1 3.4 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.5 GO:0098536 deuterosome(GO:0098536)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 1.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 4.3 GO:0030286 dynein complex(GO:0030286)
0.1 1.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.8 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0043159 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.0 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.8 GO:0042627 chylomicron(GO:0042627)
0.0 1.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 2.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 4.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.5 GO:0045095 keratin filament(GO:0045095)
0.0 3.0 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.6 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.9 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.6 GO:0004031 aldehyde oxidase activity(GO:0004031)
1.2 7.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.8 2.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.5 3.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.5 1.4 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.4 5.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 0.9 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.3 3.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 0.8 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.3 0.8 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.3 2.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 0.8 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.2 1.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 1.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 0.8 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 1.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 0.5 GO:0004566 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.2 0.5 GO:0019959 interleukin-8 binding(GO:0019959)
0.2 1.3 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.2 0.5 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 6.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 3.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.8 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.6 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 4.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 2.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.0 GO:0008430 selenium binding(GO:0008430)
0.1 1.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.9 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.7 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 3.3 GO:0043236 laminin binding(GO:0043236)
0.1 0.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 1.7 GO:0031005 filamin binding(GO:0031005)
0.1 0.3 GO:0031403 lithium ion binding(GO:0031403)
0.1 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 1.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.5 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 2.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 8.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 2.2 GO:0008009 chemokine activity(GO:0008009)
0.0 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.6 GO:0000150 recombinase activity(GO:0000150)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 3.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.6 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 3.3 GO:0003774 motor activity(GO:0003774)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 3.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.0 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 12.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.3 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 3.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 2.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 2.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 4.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 3.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.8 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME DEVELOPMENTAL BIOLOGY Genes involved in Developmental Biology
0.0 3.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase