Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for NFKB1

Z-value: 0.97

Motif logo

logo of

Transcription factors associated with NFKB1

Gene Symbol Gene ID Gene Info
NFKB1
ENSG00000109320.13 NFKB1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFKB1hg38_v1_chr4_+_102501885_102501957,
hg38_v1_chr4_+_102501298_102501474		0.523.3e-03Click!

Activity profile of NFKB1 motif

Sorted Z-values of NFKB1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_150412743 8.61 ENST00000353334.11
ENST00000009530.12
ENST00000377795.7
CD74
CD74 molecule
chr6_-_29559724 6.73 ENST00000377050.5
UBD
ubiquitin D
chr16_+_67431112 5.88 ENST00000326152.6
HSD11B2
hydroxysteroid 11-beta dehydrogenase 2
chr3_+_63652663 5.69 ENST00000343837.8
ENST00000469440.5
SNTN
sentan, cilia apical structure protein
chr10_-_13099652 4.89 ENST00000378839.1
CCDC3
coiled-coil domain containing 3
chr5_-_55173173 4.81 ENST00000296733.5
ENST00000322374.10
ENST00000381375.7
CDC20B
cell division cycle 20B
chr16_-_66925526 4.16 ENST00000299759.11
ENST00000420652.5
RRAD
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
chr17_+_42288464 4.06 ENST00000590726.7
ENST00000678903.1
ENST00000590949.6
ENST00000676585.1
ENST00000588868.5
STAT5A
signal transducer and activator of transcription 5A
chr17_+_42288429 4.06 ENST00000676631.1
ENST00000677893.1
STAT5A
signal transducer and activator of transcription 5A
chr6_+_32637419 3.36 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr19_+_45001430 3.19 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB
RELB proto-oncogene, NF-kB subunit
chr9_+_124853417 3.18 ENST00000613760.4
ENST00000618744.4
ENST00000373574.2
WDR38
WD repeat domain 38
chr9_-_127874964 2.63 ENST00000373156.5
AK1
adenylate kinase 1
chr6_+_135181323 2.60 ENST00000367814.8
MYB
MYB proto-oncogene, transcription factor
chr6_+_135181268 2.38 ENST00000341911.10
ENST00000442647.7
ENST00000618728.4
ENST00000316528.12
ENST00000616088.4
MYB
MYB proto-oncogene, transcription factor
chr7_+_17299234 2.28 ENST00000637807.1
ENSG00000283321.1
novel protein
chr6_+_32854179 2.18 ENST00000374859.3
PSMB9
proteasome 20S subunit beta 9
chr2_-_96505345 2.04 ENST00000310865.7
ENST00000451794.6
NEURL3
neuralized E3 ubiquitin protein ligase 3
chr6_+_32637396 1.93 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr10_+_12349685 1.89 ENST00000378845.5
CAMK1D
calcium/calmodulin dependent protein kinase ID
chr17_-_1628808 1.77 ENST00000301335.10
SLC43A2
solute carrier family 43 member 2
chr9_-_114505437 1.70 ENST00000374057.3
ENST00000362057.4
ENST00000673697.1
WHRN
whirlin
chr14_+_75522427 1.68 ENST00000286639.8
BATF
basic leucine zipper ATF-like transcription factor
chr14_+_75069577 1.64 ENST00000238686.8
ZC2HC1C
zinc finger C2HC-type containing 1C
chrX_-_112840815 1.62 ENST00000304758.5
ENST00000371959.9
AMOT
angiomotin
chr5_+_31639104 1.58 ENST00000438447.2
PDZD2
PDZ domain containing 2
chr10_+_12349533 1.56 ENST00000619168.5
CAMK1D
calcium/calmodulin dependent protein kinase ID
chr16_+_50742059 1.56 ENST00000311559.13
ENST00000564326.5
ENST00000566206.5
ENST00000427738.8
CYLD
CYLD lysine 63 deubiquitinase
chr11_+_102317542 1.56 ENST00000532808.5
BIRC3
baculoviral IAP repeat containing 3
chr19_+_14433284 1.53 ENST00000242783.11
PKN1
protein kinase N1
chr14_+_75069632 1.50 ENST00000439583.2
ENST00000554763.2
ENST00000524913.3
ENST00000525046.2
ENST00000674086.1
ENST00000526130.2
ENST00000674094.1
ENST00000532198.2
ZC2HC1C
zinc finger C2HC-type containing 1C
chr11_-_73142308 1.47 ENST00000409418.9
FCHSD2
FCH and double SH3 domains 2
chr11_+_102317450 1.43 ENST00000615299.4
ENST00000527309.2
ENST00000526421.6
ENST00000263464.9
BIRC3
baculoviral IAP repeat containing 3
chr6_+_137867414 1.35 ENST00000237289.8
ENST00000433680.1
TNFAIP3
TNF alpha induced protein 3
chr6_+_29723340 1.34 ENST00000334668.8
HLA-F
major histocompatibility complex, class I, F
chr15_-_26773737 1.34 ENST00000299267.8
GABRB3
gamma-aminobutyric acid type A receptor subunit beta3
chr11_+_114059702 1.29 ENST00000335953.9
ENST00000684612.1
ENST00000682810.1
ENST00000544220.1
ZBTB16
zinc finger and BTB domain containing 16
chr11_+_114059755 1.29 ENST00000684295.1
ZBTB16
zinc finger and BTB domain containing 16
chr6_+_29723421 1.29 ENST00000259951.12
ENST00000434407.6
HLA-F
major histocompatibility complex, class I, F
chr1_+_53894181 1.27 ENST00000361921.8
ENST00000322679.10
ENST00000613679.4
ENST00000617230.2
ENST00000610607.4
ENST00000532493.5
ENST00000525202.5
ENST00000524406.5
ENST00000388876.3
DIO1
iodothyronine deiodinase 1
chr19_-_48321857 1.27 ENST00000474199.6
ODAD1
outer dynein arm docking complex subunit 1
chr6_+_137867241 1.24 ENST00000612899.5
ENST00000420009.5
TNFAIP3
TNF alpha induced protein 3
chr8_+_85245451 1.21 ENST00000321764.4
CA13
carbonic anhydrase 13
chr17_+_9021501 1.20 ENST00000173229.7
NTN1
netrin 1
chr1_+_202010575 1.20 ENST00000367283.7
ENST00000367284.10
ELF3
E74 like ETS transcription factor 3
chr5_-_55994945 1.17 ENST00000381298.7
ENST00000502326.7
IL6ST
interleukin 6 signal transducer
chr7_-_120858066 1.16 ENST00000222747.8
TSPAN12
tetraspanin 12
chr6_-_111483700 1.11 ENST00000435970.5
ENST00000358835.7
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit
chr4_+_73869385 1.11 ENST00000395761.4
CXCL1
C-X-C motif chemokine ligand 1
chr19_-_48321948 1.09 ENST00000674294.1
ODAD1
outer dynein arm docking complex subunit 1
chr11_+_114060204 1.09 ENST00000683318.1
ZBTB16
zinc finger and BTB domain containing 16
chr7_-_127392310 1.09 ENST00000393312.5
ZNF800
zinc finger protein 800
chr14_+_75522531 1.08 ENST00000555504.1
BATF
basic leucine zipper ATF-like transcription factor
chr18_+_13218195 1.07 ENST00000679167.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr17_+_42289213 1.05 ENST00000677301.1
STAT5A
signal transducer and activator of transcription 5A
chr2_+_96537254 1.04 ENST00000454558.2
ARID5A
AT-rich interaction domain 5A
chr12_+_52051402 1.03 ENST00000243050.5
ENST00000550763.1
ENST00000394825.6
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4 group A member 1
chr11_+_102317492 1.02 ENST00000673846.1
BIRC3
baculoviral IAP repeat containing 3
chr3_+_119703001 0.99 ENST00000273390.9
ENST00000463700.1
ENST00000648112.1
CFAP91
ENSG00000285585.1
cilia and flagella associated protein 91
novel protein
chr16_+_50742037 0.98 ENST00000569418.5
CYLD
CYLD lysine 63 deubiquitinase
chr2_+_96536743 0.96 ENST00000673792.1
ENST00000357485.8
ARID5A
AT-rich interaction domain 5A
chr3_-_66038537 0.96 ENST00000483466.5
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr16_-_53703883 0.95 ENST00000262135.9
ENST00000564374.5
ENST00000566096.5
RPGRIP1L
RPGRIP1 like
chr16_-_53703810 0.95 ENST00000569716.1
ENST00000562588.5
ENST00000621565.5
ENST00000562230.5
ENST00000563746.5
ENST00000568653.7
ENST00000647211.2
RPGRIP1L
RPGRIP1 like
chr16_+_50742110 0.92 ENST00000566679.6
ENST00000564634.5
ENST00000398568.6
CYLD
CYLD lysine 63 deubiquitinase
chr14_-_35404650 0.91 ENST00000553342.1
ENST00000557140.5
ENST00000216797.10
NFKBIA
NFKB inhibitor alpha
chr19_+_2476118 0.90 ENST00000215631.9
ENST00000587345.1
GADD45B
growth arrest and DNA damage inducible beta
chr1_+_100352451 0.89 ENST00000361544.11
ENST00000370124.8
ENST00000336454.5
CDC14A
cell division cycle 14A
chr3_-_18425295 0.88 ENST00000338745.11
ENST00000450898.1
SATB1
SATB homeobox 1
chr10_-_71773513 0.88 ENST00000394957.8
VSIR
V-set immunoregulatory receptor
chr19_-_48646155 0.88 ENST00000084798.9
CA11
carbonic anhydrase 11
chr19_-_4338786 0.87 ENST00000601482.1
ENST00000600324.5
ENST00000594605.6
STAP2
signal transducing adaptor family member 2
chr2_-_210171402 0.87 ENST00000281772.14
KANSL1L
KAT8 regulatory NSL complex subunit 1 like
chrX_+_73447042 0.86 ENST00000373514.3
CDX4
caudal type homeobox 4
chr1_+_6785437 0.86 ENST00000303635.12
ENST00000473578.5
ENST00000557126.5
CAMTA1
calmodulin binding transcription activator 1
chr17_-_57988179 0.84 ENST00000581208.2
ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr21_-_41953997 0.84 ENST00000380486.4
C2CD2
C2 calcium dependent domain containing 2
chr17_+_7687416 0.83 ENST00000457584.6
WRAP53
WD repeat containing antisense to TP53
chr1_+_211259279 0.82 ENST00000367006.8
ENST00000419091.7
ENST00000452621.6
RCOR3
REST corepressor 3
chr11_+_64230278 0.82 ENST00000628077.2
ENST00000321685.7
DNAJC4
DnaJ heat shock protein family (Hsp40) member C4
chr14_+_103123452 0.82 ENST00000558056.1
ENST00000560869.6
TNFAIP2
TNF alpha induced protein 2
chr9_+_17579059 0.82 ENST00000380607.5
SH3GL2
SH3 domain containing GRB2 like 2, endophilin A1
chr2_-_210171327 0.80 ENST00000418791.5
ENST00000452086.5
KANSL1L
KAT8 regulatory NSL complex subunit 1 like
chr2_-_216695540 0.79 ENST00000233813.5
IGFBP5
insulin like growth factor binding protein 5
chr8_-_102655707 0.78 ENST00000285407.11
KLF10
Kruppel like factor 10
chr6_+_36196710 0.77 ENST00000357641.10
BRPF3
bromodomain and PHD finger containing 3
chr5_+_140401860 0.77 ENST00000532219.5
ENST00000394722.7
ANKHD1-EIF4EBP3
ANKHD1
ANKHD1-EIF4EBP3 readthrough
ankyrin repeat and KH domain containing 1
chr5_+_57174016 0.76 ENST00000514387.6
ENST00000506184.7
GPBP1
GC-rich promoter binding protein 1
chr2_-_162318475 0.76 ENST00000648433.1
IFIH1
interferon induced with helicase C domain 1
chr15_+_76059973 0.76 ENST00000388942.8
TMEM266
transmembrane protein 266
chr19_+_10416773 0.74 ENST00000592685.5
PDE4A
phosphodiesterase 4A
chr17_-_7219813 0.74 ENST00000399510.8
ENST00000648172.8
DLG4
discs large MAGUK scaffold protein 4
chr12_-_54981838 0.73 ENST00000316577.12
TESPA1
thymocyte expressed, positive selection associated 1
chr7_+_17298642 0.72 ENST00000242057.9
AHR
aryl hydrocarbon receptor
chr20_+_46118300 0.71 ENST00000372285.8
ENST00000372276.7
CD40
CD40 molecule
chr4_-_74038681 0.71 ENST00000296026.4
CXCL3
C-X-C motif chemokine ligand 3
chr4_+_102501298 0.68 ENST00000394820.8
ENST00000226574.9
ENST00000511926.5
ENST00000507079.5
NFKB1
nuclear factor kappa B subunit 1
chr5_+_57173948 0.68 ENST00000424459.7
GPBP1
GC-rich promoter binding protein 1
chr11_-_96343170 0.68 ENST00000524717.6
MAML2
mastermind like transcriptional coactivator 2
chr15_+_85380672 0.64 ENST00000361243.6
ENST00000560256.1
AKAP13
A-kinase anchoring protein 13
chr5_-_178627001 0.64 ENST00000611575.4
ENST00000520957.1
ENST00000316308.9
ENST00000611733.4
CLK4
CDC like kinase 4
chr1_-_155188351 0.64 ENST00000462317.5
MUC1
mucin 1, cell surface associated
chr10_-_13348270 0.64 ENST00000378614.8
ENST00000327347.10
ENST00000545675.5
SEPHS1
selenophosphate synthetase 1
chr6_+_148747016 0.63 ENST00000367463.5
UST
uronyl 2-sulfotransferase
chr17_-_7687427 0.62 ENST00000514944.5
ENST00000503591.1
ENST00000610292.4
ENST00000420246.6
ENST00000455263.6
ENST00000610538.4
ENST00000622645.4
ENST00000445888.6
ENST00000619485.4
ENST00000509690.5
ENST00000604348.5
ENST00000269305.9
ENST00000620739.4
TP53
tumor protein p53
chr4_-_121164314 0.61 ENST00000057513.8
TNIP3
TNFAIP3 interacting protein 3
chr1_-_10796636 0.60 ENST00000377022.8
ENST00000344008.5
CASZ1
castor zinc finger 1
chr11_+_72814380 0.59 ENST00000534905.5
ENST00000321297.10
ENST00000540567.1
ATG16L2
autophagy related 16 like 2
chr17_-_7294592 0.59 ENST00000007699.10
YBX2
Y-box binding protein 2
chr14_+_102777433 0.59 ENST00000392745.8
TRAF3
TNF receptor associated factor 3
chr3_-_187737943 0.58 ENST00000438077.1
BCL6
BCL6 transcription repressor
chr15_-_75451543 0.58 ENST00000394949.8
SIN3A
SIN3 transcription regulator family member A
chr11_-_73142032 0.57 ENST00000311172.11
ENST00000409314.5
FCHSD2
FCH and double SH3 domains 2
chr1_+_89524871 0.57 ENST00000639264.1
LRRC8B
leucine rich repeat containing 8 VRAC subunit B
chr20_-_51542658 0.57 ENST00000396009.7
ENST00000371564.8
ENST00000610033.5
NFATC2
nuclear factor of activated T cells 2
chr12_+_48105466 0.57 ENST00000549003.5
ENST00000550924.6
PFKM
phosphofructokinase, muscle
chr11_+_65525067 0.57 ENST00000525364.5
ENST00000270176.10
ENST00000420247.6
ENST00000533862.5
ENST00000524944.5
SCYL1
SCY1 like pseudokinase 1
chr11_+_34621109 0.57 ENST00000450654.6
EHF
ETS homologous factor
chr7_+_101817601 0.57 ENST00000292535.12
ENST00000546411.7
ENST00000549414.6
ENST00000550008.6
ENST00000556210.1
CUX1
cut like homeobox 1
chr15_-_88895511 0.57 ENST00000562281.1
ENST00000359595.8
ENST00000562889.5
HAPLN3
hyaluronan and proteoglycan link protein 3
chr13_+_76992412 0.56 ENST00000636705.1
CLN5
CLN5 intracellular trafficking protein
chr5_-_135895834 0.54 ENST00000274520.2
IL9
interleukin 9
chr13_-_77918788 0.54 ENST00000626030.1
EDNRB
endothelin receptor type B
chr2_+_38666059 0.54 ENST00000272252.10
ENST00000410063.5
GALM
galactose mutarotase
chr19_-_45322867 0.53 ENST00000221476.4
CKM
creatine kinase, M-type
chr4_-_74099187 0.53 ENST00000508487.3
CXCL2
C-X-C motif chemokine ligand 2
chr18_+_13217676 0.53 ENST00000679177.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr15_+_73052449 0.52 ENST00000261908.11
NEO1
neogenin 1
chr14_+_102777461 0.50 ENST00000560371.5
ENST00000347662.8
TRAF3
TNF receptor associated factor 3
chr1_+_26787926 0.50 ENST00000674202.1
ENST00000674222.1
PIGV
phosphatidylinositol glycan anchor biosynthesis class V
chr19_+_35449584 0.50 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr11_+_65525413 0.49 ENST00000527009.5
SCYL1
SCY1 like pseudokinase 1
chr1_+_63367619 0.49 ENST00000263440.6
ALG6
ALG6 alpha-1,3-glucosyltransferase
chr1_+_89524819 0.49 ENST00000439853.6
ENST00000330947.7
ENST00000449440.5
ENST00000640258.1
LRRC8B
leucine rich repeat containing 8 VRAC subunit B
chr2_-_152099155 0.48 ENST00000637309.1
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr1_+_27234612 0.48 ENST00000319394.8
ENST00000361771.7
WDTC1
WD and tetratricopeptide repeats 1
chr6_-_142946312 0.48 ENST00000367604.6
HIVEP2
HIVEP zinc finger 2
chr19_-_4540028 0.48 ENST00000306390.7
LRG1
leucine rich alpha-2-glycoprotein 1
chr3_-_45226268 0.48 ENST00000503771.2
TMEM158
transmembrane protein 158
chr13_+_97222296 0.48 ENST00000343600.8
ENST00000376673.7
ENST00000679496.1
ENST00000345429.10
MBNL2
muscleblind like splicing regulator 2
chr6_-_27312258 0.47 ENST00000444565.2
POM121L2
POM121 transmembrane nucleoporin like 2
chr22_-_37953541 0.47 ENST00000422191.1
ENST00000249079.6
ENST00000403305.6
ENST00000418863.5
ENST00000619227.4
ENST00000403026.5
C22orf23
chromosome 22 open reading frame 23
chr1_-_235649734 0.47 ENST00000391854.7
GNG4
G protein subunit gamma 4
chr5_+_140401808 0.47 ENST00000616482.4
ENST00000297183.10
ENST00000360839.7
ENST00000421134.5
ENST00000394723.7
ENST00000511151.5
ANKHD1
ankyrin repeat and KH domain containing 1
chr2_+_32628026 0.47 ENST00000448773.5
ENST00000317907.9
TTC27
tetratricopeptide repeat domain 27
chr9_-_83817632 0.46 ENST00000376365.7
ENST00000376371.7
GKAP1
G kinase anchoring protein 1
chr16_-_73048104 0.46 ENST00000268489.10
ZFHX3
zinc finger homeobox 3
chr15_+_44427591 0.46 ENST00000558791.5
ENST00000260327.9
CTDSPL2
CTD small phosphatase like 2
chr1_+_107141022 0.46 ENST00000370067.5
ENST00000370068.6
NTNG1
netrin G1
chrX_+_40580894 0.46 ENST00000636409.1
ENST00000637327.1
ENST00000637526.1
ENST00000638153.1
ENST00000378438.9
ENST00000636970.1
ENST00000636196.1
ENST00000636251.1
ENST00000637482.1
ENST00000636580.2
ENST00000423649.2
ENST00000636287.1
ATP6AP2
ATPase H+ transporting accessory protein 2
chr12_+_6943811 0.45 ENST00000544681.1
ENST00000537087.5
C12orf57
chromosome 12 open reading frame 57
chr11_-_77474087 0.45 ENST00000356341.8
PAK1
p21 (RAC1) activated kinase 1
chr3_-_50567711 0.44 ENST00000357203.8
C3orf18
chromosome 3 open reading frame 18
chr12_+_11171166 0.44 ENST00000622602.2
SMIM10L1
small integral membrane protein 10 like 1
chr11_+_34621065 0.44 ENST00000257831.8
EHF
ETS homologous factor
chr1_+_26787667 0.43 ENST00000674335.1
PIGV
phosphatidylinositol glycan anchor biosynthesis class V
chr15_+_88803426 0.43 ENST00000560601.4
ENST00000561243.7
ENST00000439576.7
ACAN
aggrecan
chr5_+_68215738 0.43 ENST00000521381.6
ENST00000521657.5
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
chr12_+_6944009 0.43 ENST00000229281.6
C12orf57
chromosome 12 open reading frame 57
chr19_-_33064872 0.42 ENST00000254260.8
RHPN2
rhophilin Rho GTPase binding protein 2
chr1_+_156153568 0.42 ENST00000368284.5
ENST00000368286.6
ENST00000368285.8
ENST00000438830.5
SEMA4A
semaphorin 4A
chr15_+_44427793 0.42 ENST00000558966.5
ENST00000559793.5
ENST00000558968.1
CTDSPL2
CTD small phosphatase like 2
chr15_-_75451650 0.41 ENST00000567289.5
ENST00000394947.8
ENST00000565264.1
SIN3A
SIN3 transcription regulator family member A
chr12_+_6944065 0.41 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr5_-_96807899 0.41 ENST00000503921.5
ENST00000508227.5
ENST00000507154.1
ENST00000443439.7
ERAP1
endoplasmic reticulum aminopeptidase 1
chrX_-_84188148 0.41 ENST00000262752.5
RPS6KA6
ribosomal protein S6 kinase A6
chr3_+_53161120 0.40 ENST00000394729.6
ENST00000330452.8
ENST00000652449.1
PRKCD
protein kinase C delta
chr3_+_53161241 0.40 ENST00000477794.2
ENST00000650739.1
PRKCD
protein kinase C delta
chr6_+_33200860 0.40 ENST00000374677.8
SLC39A7
solute carrier family 39 member 7
chr2_+_60881515 0.40 ENST00000295025.12
REL
REL proto-oncogene, NF-kB subunit
chr2_+_60881553 0.39 ENST00000394479.4
REL
REL proto-oncogene, NF-kB subunit
chr8_+_41578176 0.39 ENST00000396987.7
ENST00000519853.5
GPAT4
glycerol-3-phosphate acyltransferase 4
chr9_+_79573162 0.39 ENST00000425506.5
TLE4
TLE family member 4, transcriptional corepressor
chr11_+_560956 0.38 ENST00000397582.7
ENST00000397583.8
RASSF7
Ras association domain family member 7
chr2_-_152099023 0.38 ENST00000201943.10
ENST00000427385.6
ENST00000539935.7
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr1_-_151327365 0.38 ENST00000438243.2
ENST00000489223.2
ENST00000368873.6
ENST00000430800.5
ENST00000368872.5
PI4KB
phosphatidylinositol 4-kinase beta
chr2_+_42494547 0.37 ENST00000405592.5
MTA3
metastasis associated 1 family member 3
chr6_+_87590067 0.37 ENST00000546266.5
ENST00000257789.4
ENST00000392844.8
ORC3
origin recognition complex subunit 3
chr8_-_12755457 0.37 ENST00000398246.8
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr17_+_7834200 0.37 ENST00000448097.7
KDM6B
lysine demethylase 6B
chr6_+_33200820 0.37 ENST00000374675.7
SLC39A7
solute carrier family 39 member 7
chr15_+_47184076 0.36 ENST00000558014.5
SEMA6D
semaphorin 6D
chr17_+_21288029 0.36 ENST00000526076.6
ENST00000361818.9
ENST00000316920.10
MAP2K3
mitogen-activated protein kinase kinase 3
chr6_+_41546340 0.35 ENST00000307972.10
ENST00000373063.7
FOXP4
forkhead box P4
chr1_+_6785518 0.35 ENST00000467404.6
CAMTA1
calmodulin binding transcription activator 1
chr1_+_32886456 0.35 ENST00000373467.4
HPCA
hippocalcin
chr5_+_10564064 0.35 ENST00000296657.7
ANKRD33B
ankyrin repeat domain 33B
chrX_+_69504320 0.35 ENST00000252338.5
FAM155B
family with sequence similarity 155 member B
chr13_+_38687068 0.35 ENST00000280481.9
FREM2
FRAS1 related extracellular matrix 2
chr3_+_157436842 0.35 ENST00000295927.4
PTX3
pentraxin 3
chr3_-_50567646 0.35 ENST00000426034.5
ENST00000441239.5
C3orf18
chromosome 3 open reading frame 18
chr13_+_108269880 0.34 ENST00000542136.1
TNFSF13B
TNF superfamily member 13b
chr11_-_77474041 0.33 ENST00000278568.8
PAK1
p21 (RAC1) activated kinase 1
chr15_+_85380565 0.33 ENST00000559362.5
ENST00000394518.7
AKAP13
A-kinase anchoring protein 13
chr2_-_152098810 0.33 ENST00000636442.1
ENST00000638005.1
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr14_-_50831046 0.33 ENST00000476352.5
ENST00000324330.13
ENST00000382041.7
ENST00000453401.6
ENST00000530997.7
NIN
ninein
chr17_+_4731410 0.33 ENST00000575284.5
ENST00000293777.6
ENST00000674339.1
ENST00000573708.1
MED11
mediator complex subunit 11
chr7_-_127392687 0.32 ENST00000393313.5
ENST00000619291.4
ENST00000265827.8
ENST00000434602.5
ZNF800
zinc finger protein 800
chr2_+_207529731 0.31 ENST00000430624.5
CREB1
cAMP responsive element binding protein 1
chr19_+_55283982 0.31 ENST00000309383.6
BRSK1
BR serine/threonine kinase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
1.7 5.0 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
1.3 9.2 GO:0000255 allantoin metabolic process(GO:0000255)
1.0 4.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.9 3.5 GO:1990108 protein linear deubiquitination(GO:1990108)
0.9 2.6 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.8 6.7 GO:0070842 aggresome assembly(GO:0070842)
0.6 3.7 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.5 0.9 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.4 1.5 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.4 3.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 1.0 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.3 5.9 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.3 4.0 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.3 2.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.3 0.8 GO:2000755 regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
0.3 0.8 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.2 0.7 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.2 4.0 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.2 0.6 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.2 0.6 GO:0009386 translational attenuation(GO:0009386)
0.2 1.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 0.7 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 4.9 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.2 0.5 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.2 0.2 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.2 0.9 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 0.7 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.2 0.5 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.2 1.3 GO:0021678 third ventricle development(GO:0021678)
0.2 0.6 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.2 0.8 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.2 1.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.6 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.7 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1 1.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.7 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.4 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.1 0.9 GO:0033590 response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018)
0.1 1.9 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.5 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.1 0.4 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.8 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.6 GO:0048294 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.3 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.1 1.0 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.8 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1 0.4 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 2.8 GO:0042832 defense response to protozoan(GO:0042832)
0.1 0.3 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.6 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.3 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.1 0.3 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 1.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.6 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 1.2 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.4 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.1 0.2 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.6 GO:0006477 protein sulfation(GO:0006477)
0.1 0.8 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 1.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.5 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 2.0 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.1 0.6 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.2 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.1 1.3 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.8 GO:0051601 exocyst localization(GO:0051601)
0.1 1.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.5 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.0 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 6.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.1 GO:1900222 regulation of cell growth by extracellular stimulus(GO:0001560) phenotypic switching(GO:0036166) negative regulation of beta-amyloid clearance(GO:1900222) regulation of phenotypic switching(GO:1900239) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.1 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 1.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.2 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.0 0.6 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.0 GO:1901740 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) negative regulation of myoblast fusion(GO:1901740)
0.0 2.6 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:1904908 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.0 0.4 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 4.8 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 2.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.0 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 1.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 1.8 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.6 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 1.1 GO:0010842 retina layer formation(GO:0010842)
0.0 1.6 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.5 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.0 0.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 1.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.4 GO:0021591 ventricular system development(GO:0021591)
0.0 1.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.5 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 1.0 GO:0060711 labyrinthine layer development(GO:0060711)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 1.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.5 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.4 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.6 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.6 GO:0014904 myotube cell development(GO:0014904)
0.0 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.9 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 8.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.4 5.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.4 1.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.3 5.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 2.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 2.8 GO:0042611 MHC protein complex(GO:0042611)
0.2 0.7 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.2 1.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 1.9 GO:0005879 axonemal microtubule(GO:0005879)
0.2 0.9 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 2.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.7 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.4 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 1.4 GO:0060091 kinocilium(GO:0060091)
0.1 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 6.7 GO:0016235 aggresome(GO:0016235)
0.1 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.9 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 3.5 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.0 1.0 GO:0016580 Sin3 complex(GO:0016580)
0.0 2.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 7.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.9 GO:0071437 invadopodium(GO:0071437)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0044615 nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 3.2 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 1.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 1.6 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.0 GO:0005592 collagen type XI trimer(GO:0005592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.2 8.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.6 1.9 GO:0031862 prostanoid receptor binding(GO:0031862)
0.5 4.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.4 5.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 5.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4 1.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 2.7 GO:0046979 TAP2 binding(GO:0046979)
0.3 6.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 0.9 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.3 1.2 GO:0004923 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.3 1.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 0.7 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 3.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 5.9 GO:0070628 proteasome binding(GO:0070628)
0.1 2.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 1.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.5 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.7 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 2.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.3 GO:0035375 zymogen binding(GO:0035375)
0.1 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.7 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 3.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 2.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.2 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.1 0.7 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 2.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.6 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 3.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.7 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.6 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 10.3 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 1.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 1.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.4 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 5.1 GO:0001047 core promoter binding(GO:0001047)
0.0 7.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.6 PID IL5 PATHWAY IL5-mediated signaling events
0.1 9.5 PID CD40 PATHWAY CD40/CD40L signaling
0.1 5.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 4.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.6 PID IL27 PATHWAY IL27-mediated signaling events
0.0 4.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 2.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.4 PID AURORA A PATHWAY Aurora A signaling
0.0 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 ST ADRENERGIC Adrenergic Pathway
0.0 0.6 PID FOXO PATHWAY FoxO family signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 2.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 5.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 9.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.8 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 2.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 1.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.9 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 2.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 7.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 6.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.8 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.7 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 3.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling