Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for NFKB2

Z-value: 0.75

Motif logo

logo of

Transcription factors associated with NFKB2

Gene Symbol Gene ID Gene Info
NFKB2
ENSG00000077150.20 NFKB2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFKB2hg38_v1_chr10_+_102394488_1023945400.203.0e-01Click!

Activity profile of NFKB2 motif

Sorted Z-values of NFKB2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr22_-_37244417 1.83 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
RAC2
Rac family small GTPase 2
chr8_+_85463997 1.77 ENST00000285379.10
CA2
carbonic anhydrase 2
chr22_-_37244237 1.72 ENST00000401529.3
ENST00000249071.11
RAC2
Rac family small GTPase 2
chr4_-_73998669 1.45 ENST00000296027.5
CXCL5
C-X-C motif chemokine ligand 5
chr3_+_111999326 1.40 ENST00000494932.1
TAGLN3
transgelin 3
chr19_+_2096960 1.36 ENST00000588003.5
IZUMO4
IZUMO family member 4
chr4_+_17810945 1.33 ENST00000251496.7
NCAPG
non-SMC condensin I complex subunit G
chr1_-_186680411 1.31 ENST00000367468.10
PTGS2
prostaglandin-endoperoxide synthase 2
chr15_-_74725370 1.28 ENST00000567032.5
ENST00000564596.5
ENST00000566503.1
ENST00000395049.8
ENST00000379727.8
ENST00000617691.4
ENST00000395048.6
CYP1A1
cytochrome P450 family 1 subfamily A member 1
chr19_+_2097010 1.24 ENST00000610800.1
IZUMO4
IZUMO family member 4
chr18_+_23949847 1.23 ENST00000588004.1
LAMA3
laminin subunit alpha 3
chr19_+_2096937 1.22 ENST00000395296.5
IZUMO4
IZUMO family member 4
chrX_+_65667645 1.20 ENST00000360270.7
MSN
moesin
chr8_+_53880894 1.20 ENST00000276500.4
RGS20
regulator of G protein signaling 20
chrX_+_103918872 1.19 ENST00000419165.5
TMSB15B
thymosin beta 15B
chr8_+_53880867 1.17 ENST00000522225.5
RGS20
regulator of G protein signaling 20
chr21_-_43659460 1.15 ENST00000443485.1
ENST00000291560.7
HSF2BP
heat shock transcription factor 2 binding protein
chr19_+_48321454 1.15 ENST00000599704.5
EMP3
epithelial membrane protein 3
chrX_-_154366334 1.14 ENST00000673639.2
FLNA
filamin A
chr12_-_57767057 1.12 ENST00000228606.9
CYP27B1
cytochrome P450 family 27 subfamily B member 1
chr12_+_53097656 1.08 ENST00000301464.4
IGFBP6
insulin like growth factor binding protein 6
chr15_+_85380625 1.05 ENST00000560302.5
AKAP13
A-kinase anchoring protein 13
chr3_+_111998739 0.98 ENST00000393917.6
ENST00000273368.8
TAGLN3
transgelin 3
chr3_+_111999189 0.96 ENST00000455401.6
TAGLN3
transgelin 3
chr11_-_66907891 0.96 ENST00000393955.6
PC
pyruvate carboxylase
chr1_-_26360050 0.94 ENST00000475866.3
CRYBG2
crystallin beta-gamma domain containing 2
chr3_+_111998915 0.92 ENST00000478951.6
TAGLN3
transgelin 3
chr1_-_37634864 0.89 ENST00000356545.7
RSPO1
R-spondin 1
chr10_+_110497898 0.88 ENST00000369583.4
DUSP5
dual specificity phosphatase 5
chr19_+_53867874 0.86 ENST00000448420.5
ENST00000439000.5
ENST00000391771.1
ENST00000391770.9
MYADM
myeloid associated differentiation marker
chr22_-_38317380 0.83 ENST00000413574.6
CSNK1E
casein kinase 1 epsilon
chr16_-_74700786 0.82 ENST00000306247.11
ENST00000575686.1
MLKL
mixed lineage kinase domain like pseudokinase
chr2_+_64454506 0.82 ENST00000409537.2
LGALSL
galectin like
chrX_-_15854743 0.78 ENST00000450644.2
AP1S2
adaptor related protein complex 1 subunit sigma 2
chr1_-_6485433 0.76 ENST00000535355.6
PLEKHG5
pleckstrin homology and RhoGEF domain containing G5
chr20_+_45174894 0.75 ENST00000243924.4
PI3
peptidase inhibitor 3
chr5_-_138331770 0.75 ENST00000415130.6
ENST00000323760.11
ENST00000503022.5
CDC25C
cell division cycle 25C
chr3_-_50303565 0.74 ENST00000266031.8
ENST00000395143.6
ENST00000457214.6
ENST00000447605.2
ENST00000395144.7
ENST00000418723.1
HYAL1
hyaluronidase 1
chr1_-_112956063 0.73 ENST00000538576.5
ENST00000369626.8
ENST00000458229.6
SLC16A1
solute carrier family 16 member 1
chr16_-_74700845 0.72 ENST00000308807.12
ENST00000573267.1
MLKL
mixed lineage kinase domain like pseudokinase
chr2_-_89010515 0.70 ENST00000493819.1
IGKV1-9
immunoglobulin kappa variable 1-9
chr10_+_92591733 0.70 ENST00000676647.1
KIF11
kinesin family member 11
chr12_+_109573757 0.67 ENST00000228510.8
ENST00000539696.5
ENST00000392727.7
MVK
mevalonate kinase
chr22_+_43923755 0.66 ENST00000423180.2
ENST00000216180.8
PNPLA3
patatin like phospholipase domain containing 3
chr7_+_151114597 0.64 ENST00000335367.7
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr1_-_208244375 0.63 ENST00000367033.4
PLXNA2
plexin A2
chr2_-_88947820 0.62 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr12_-_54419259 0.62 ENST00000293379.9
ITGA5
integrin subunit alpha 5
chr4_-_20984011 0.61 ENST00000382149.9
KCNIP4
potassium voltage-gated channel interacting protein 4
chr19_-_1513189 0.60 ENST00000395467.6
ADAMTSL5
ADAMTS like 5
chr3_-_108589375 0.60 ENST00000625495.1
ENST00000619684.4
ENST00000295746.13
CIP2A
cellular inhibitor of PP2A
chr11_+_61792878 0.59 ENST00000305885.3
ENST00000535723.1
FEN1
flap structure-specific endonuclease 1
chr19_+_44643798 0.59 ENST00000344956.8
PVR
PVR cell adhesion molecule
chr22_+_35400115 0.57 ENST00000382011.9
ENST00000216122.9
ENST00000416905.1
MCM5
minichromosome maintenance complex component 5
chr1_+_111227610 0.56 ENST00000369744.6
CHI3L2
chitinase 3 like 2
chr19_-_4831689 0.56 ENST00000248244.6
TICAM1
toll like receptor adaptor molecule 1
chr11_+_67056805 0.55 ENST00000308831.7
RHOD
ras homolog family member D
chr12_+_6914571 0.55 ENST00000229277.6
ENST00000538763.5
ENST00000545045.6
ENO2
enolase 2
chr1_-_209651291 0.54 ENST00000391911.5
ENST00000415782.1
LAMB3
laminin subunit beta 3
chr1_+_165895583 0.54 ENST00000470820.1
UCK2
uridine-cytidine kinase 2
chr1_+_165895564 0.54 ENST00000469256.6
UCK2
uridine-cytidine kinase 2
chr16_+_88638569 0.54 ENST00000244241.5
IL17C
interleukin 17C
chr16_-_87869497 0.54 ENST00000261622.5
SLC7A5
solute carrier family 7 member 5
chr14_-_50830479 0.53 ENST00000382043.8
NIN
ninein
chr1_+_111227699 0.53 ENST00000369748.9
CHI3L2
chitinase 3 like 2
chr20_+_61599755 0.52 ENST00000543233.2
CDH4
cadherin 4
chr17_-_5583957 0.51 ENST00000354411.7
ENST00000577119.5
NLRP1
NLR family pyrin domain containing 1
chr3_-_197298558 0.51 ENST00000656944.1
ENST00000346964.6
ENST00000448528.6
ENST00000655488.1
ENST00000357674.9
ENST00000667157.1
ENST00000661336.1
ENST00000654737.1
ENST00000659716.1
ENST00000657381.1
DLG1
discs large MAGUK scaffold protein 1
chrX_-_15854791 0.50 ENST00000545766.7
ENST00000380291.5
ENST00000672987.1
ENST00000329235.6
AP1S2
adaptor related protein complex 1 subunit sigma 2
chr1_-_154970735 0.50 ENST00000368445.9
ENST00000448116.7
ENST00000368449.8
SHC1
SHC adaptor protein 1
chr10_-_84241538 0.48 ENST00000372105.4
LRIT1
leucine rich repeat, Ig-like and transmembrane domains 1
chrX_+_68829009 0.48 ENST00000204961.5
EFNB1
ephrin B1
chr11_+_706595 0.48 ENST00000531348.5
ENST00000530636.5
EPS8L2
EPS8 like 2
chr5_+_136058849 0.48 ENST00000508076.5
TGFBI
transforming growth factor beta induced
chr1_-_205775182 0.48 ENST00000446390.6
RAB29
RAB29, member RAS oncogene family
chr12_+_112938523 0.48 ENST00000679483.1
ENST00000679493.1
OAS3
2'-5'-oligoadenylate synthetase 3
chr12_+_112938284 0.47 ENST00000681346.1
OAS3
2'-5'-oligoadenylate synthetase 3
chr20_-_45124463 0.47 ENST00000372785.3
WFDC12
WAP four-disulfide core domain 12
chr7_-_1556194 0.46 ENST00000297477.10
TMEM184A
transmembrane protein 184A
chr17_+_4951080 0.46 ENST00000521811.5
ENST00000323997.10
ENST00000522249.5
ENST00000519584.5
ENST00000519602.6
ENO3
enolase 3
chr11_+_706196 0.46 ENST00000534755.5
ENST00000650127.1
EPS8L2
EPS8 like 2
chr1_-_205775449 0.46 ENST00000235932.8
ENST00000437324.6
ENST00000414729.1
ENST00000367139.8
RAB29
RAB29, member RAS oncogene family
chr8_-_9150648 0.45 ENST00000310455.4
PPP1R3B
protein phosphatase 1 regulatory subunit 3B
chr16_+_28824116 0.44 ENST00000568266.5
ATXN2L
ataxin 2 like
chr19_+_54451290 0.44 ENST00000610347.1
LENG8
leukocyte receptor cluster member 8
chr11_-_64803152 0.43 ENST00000439069.5
ENST00000294066.7
ENST00000377350.7
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr1_-_6485941 0.43 ENST00000676287.1
ENST00000400913.6
PLEKHG5
pleckstrin homology and RhoGEF domain containing G5
chr5_-_78648718 0.43 ENST00000380345.7
LHFPL2
LHFPL tetraspan subfamily member 2
chr14_+_51847145 0.43 ENST00000615906.4
GNG2
G protein subunit gamma 2
chr19_-_51723968 0.42 ENST00000222115.5
ENST00000540069.7
HAS1
hyaluronan synthase 1
chr8_-_144416481 0.42 ENST00000276833.9
SLC39A4
solute carrier family 39 member 4
chr4_+_141636923 0.42 ENST00000529613.5
IL15
interleukin 15
chr3_+_12287962 0.42 ENST00000643197.2
ENST00000644622.2
PPARG
peroxisome proliferator activated receptor gamma
chr11_+_706222 0.41 ENST00000318562.13
ENST00000533500.5
EPS8L2
EPS8 like 2
chr11_+_706117 0.41 ENST00000533256.5
ENST00000614442.4
EPS8L2
EPS8 like 2
chr12_-_76878985 0.41 ENST00000547435.1
ENST00000552330.5
ENST00000311083.10
ENST00000546966.5
CSRP2
cysteine and glycine rich protein 2
chr3_+_12287899 0.41 ENST00000643888.2
PPARG
peroxisome proliferator activated receptor gamma
chr19_+_44643902 0.41 ENST00000403059.8
ENST00000425690.8
PVR
PVR cell adhesion molecule
chr1_-_231241090 0.40 ENST00000451322.1
C1orf131
chromosome 1 open reading frame 131
chr11_+_119185469 0.40 ENST00000525131.5
ENST00000355547.10
ENST00000531114.5
ENST00000322712.4
PDZD3
PDZ domain containing 3
chr1_-_151993822 0.40 ENST00000368811.8
S100A10
S100 calcium binding protein A10
chr3_+_12287859 0.40 ENST00000309576.11
ENST00000397015.7
PPARG
peroxisome proliferator activated receptor gamma
chr2_-_223838022 0.40 ENST00000444408.1
AP1S3
adaptor related protein complex 1 subunit sigma 3
chr7_+_142332182 0.40 ENST00000547918.2
TRBV7-1
T cell receptor beta variable 7-1 (non-functional)
chr2_-_218292496 0.40 ENST00000258412.8
ENST00000445635.5
ENST00000413976.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr11_-_18248632 0.40 ENST00000524555.3
ENST00000528349.5
ENST00000526900.1
ENST00000529528.5
ENST00000414546.6
SAA2-SAA4
SAA2
SAA2-SAA4 readthrough
serum amyloid A2
chr19_+_44644025 0.39 ENST00000406449.8
PVR
PVR cell adhesion molecule
chr17_-_7205116 0.39 ENST00000649520.1
ENST00000649186.1
DLG4
discs large MAGUK scaffold protein 4
chr2_-_223837484 0.39 ENST00000446015.6
ENST00000409375.1
AP1S3
adaptor related protein complex 1 subunit sigma 3
chr6_+_32637419 0.38 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr7_+_143316105 0.38 ENST00000343257.7
ENST00000650516.1
CLCN1
chloride voltage-gated channel 1
chr1_-_147172456 0.38 ENST00000254101.4
PRKAB2
protein kinase AMP-activated non-catalytic subunit beta 2
chr19_-_49896868 0.38 ENST00000593956.5
ENST00000391826.7
IL4I1
interleukin 4 induced 1
chr1_-_41662298 0.38 ENST00000643665.1
HIVEP3
HIVEP zinc finger 3
chr19_+_1407731 0.38 ENST00000592453.2
DAZAP1
DAZ associated protein 1
chr3_+_183253795 0.37 ENST00000460419.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr19_-_45423481 0.37 ENST00000589381.5
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit
chr1_-_159945596 0.37 ENST00000361509.7
ENST00000611023.1
ENST00000368094.6
IGSF9
immunoglobulin superfamily member 9
chr11_+_65919480 0.37 ENST00000527119.5
DRAP1
DR1 associated protein 1
chr19_-_3786254 0.37 ENST00000585778.5
MATK
megakaryocyte-associated tyrosine kinase
chr2_+_173075714 0.36 ENST00000409176.6
ENST00000338983.7
ENST00000375213.8
MAP3K20
mitogen-activated protein kinase kinase kinase 20
chr11_+_65919383 0.36 ENST00000312515.7
DRAP1
DR1 associated protein 1
chr1_-_27356471 0.36 ENST00000486046.5
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr10_-_131981948 0.36 ENST00000633835.1
BNIP3
BCL2 interacting protein 3
chr11_+_35618450 0.36 ENST00000317811.6
FJX1
four-jointed box kinase 1
chr22_+_25564818 0.35 ENST00000619906.4
GRK3
G protein-coupled receptor kinase 3
chr17_-_1486124 0.35 ENST00000575158.5
MYO1C
myosin IC
chrX_-_49184789 0.35 ENST00000453382.5
ENST00000432913.5
PRICKLE3
prickle planar cell polarity protein 3
chr1_-_40862354 0.35 ENST00000372638.4
CITED4
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4
chr11_-_18248662 0.35 ENST00000256733.9
SAA2
serum amyloid A2
chr11_+_65919261 0.35 ENST00000525501.5
DRAP1
DR1 associated protein 1
chr19_-_14518383 0.35 ENST00000254322.3
ENST00000595139.2
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1
chr11_+_65919687 0.34 ENST00000532933.1
DRAP1
DR1 associated protein 1
chr8_+_22999535 0.34 ENST00000251822.7
RHOBTB2
Rho related BTB domain containing 2
chr19_-_45423839 0.34 ENST00000340192.11
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit
chr10_-_131981912 0.34 ENST00000540159.3
BNIP3
BCL2 interacting protein 3
chr16_+_15643267 0.34 ENST00000396355.5
NDE1
nudE neurodevelopment protein 1
chr5_+_60945193 0.33 ENST00000296597.10
ENST00000511107.1
ENST00000677932.1
ENST00000502658.1
NDUFAF2
NADH:ubiquinone oxidoreductase complex assembly factor 2
chr2_+_173075435 0.33 ENST00000539448.5
MAP3K20
mitogen-activated protein kinase kinase kinase 20
chr11_+_65919331 0.33 ENST00000376991.6
DRAP1
DR1 associated protein 1
chrX_-_142205260 0.33 ENST00000247452.4
MAGEC2
MAGE family member C2
chr9_-_137070548 0.33 ENST00000409687.5
SAPCD2
suppressor APC domain containing 2
chr7_-_44189428 0.32 ENST00000673284.1
ENST00000403799.8
ENST00000671824.1
GCK
glucokinase
chr10_+_122271292 0.32 ENST00000260723.6
BTBD16
BTB domain containing 16
chrX_-_23743201 0.32 ENST00000492081.1
ENST00000379303.10
ENST00000336430.11
ACOT9
acyl-CoA thioesterase 9
chr19_-_41353904 0.32 ENST00000221930.6
TGFB1
transforming growth factor beta 1
chr1_-_183635776 0.31 ENST00000359856.11
ARPC5
actin related protein 2/3 complex subunit 5
chr16_+_28823212 0.31 ENST00000570200.5
ATXN2L
ataxin 2 like
chr1_-_71047803 0.31 ENST00000370932.6
ENST00000628037.2
ENST00000351052.9
ENST00000354608.9
ENST00000370924.4
PTGER3
prostaglandin E receptor 3
chr2_-_88992903 0.31 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr9_+_38392694 0.31 ENST00000377698.4
ENST00000635162.1
ALDH1B1
aldehyde dehydrogenase 1 family member B1
chr3_-_48595267 0.31 ENST00000328333.12
ENST00000681320.1
COL7A1
collagen type VII alpha 1 chain
chr1_-_150234668 0.31 ENST00000616917.4
ANP32E
acidic nuclear phosphoprotein 32 family member E
chr11_-_2903490 0.31 ENST00000455942.3
ENST00000625099.4
SLC22A18AS
solute carrier family 22 member 18 antisense
chr16_-_68236069 0.31 ENST00000473183.7
ENST00000565858.5
ESRP2
epithelial splicing regulatory protein 2
chr8_-_143840940 0.31 ENST00000442628.7
NRBP2
nuclear receptor binding protein 2
chr5_+_177303768 0.30 ENST00000303204.9
ENST00000503216.5
PRELID1
PRELI domain containing 1
chr16_-_28211908 0.30 ENST00000566073.1
ENST00000304658.10
XPO6
exportin 6
chr1_+_28259473 0.30 ENST00000253063.4
SESN2
sestrin 2
chr19_-_14529193 0.30 ENST00000596853.6
ENST00000676515.1
ENST00000678338.1
ENST00000595992.6
ENST00000677848.1
ENST00000677762.1
ENST00000678009.1
ENST00000596075.2
ENST00000601533.6
ENST00000396969.8
ENST00000598692.2
ENST00000678098.1
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1
chr12_+_112938422 0.30 ENST00000680044.1
ENST00000680966.1
ENST00000548514.2
ENST00000681497.1
ENST00000551007.1
ENST00000228928.12
ENST00000680438.1
ENST00000681147.1
ENST00000679354.1
ENST00000681085.1
ENST00000680161.1
OAS3
2'-5'-oligoadenylate synthetase 3
chr6_+_32637396 0.30 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr19_-_48898737 0.30 ENST00000221399.8
TULP2
TUB like protein 2
chr20_+_36461747 0.30 ENST00000340491.8
DLGAP4
DLG associated protein 4
chr17_-_1485733 0.30 ENST00000648446.1
MYO1C
myosin IC
chr17_-_44830774 0.30 ENST00000590758.3
ENST00000591424.5
GJC1
gap junction protein gamma 1
chr12_+_100267220 0.29 ENST00000635101.1
SCYL2
SCY1 like pseudokinase 2
chr19_-_45423501 0.28 ENST00000591636.5
ENST00000013807.9
ENST00000592023.5
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit
chr19_-_14517425 0.28 ENST00000676577.1
ENST00000677204.1
ENST00000598235.2
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1
chr8_-_61646807 0.28 ENST00000522919.5
ASPH
aspartate beta-hydroxylase
chr16_+_81444799 0.28 ENST00000537098.8
CMIP
c-Maf inducing protein
chr1_+_184051865 0.27 ENST00000644815.1
TSEN15
tRNA splicing endonuclease subunit 15
chr1_+_109910892 0.27 ENST00000369802.7
ENST00000420111.6
CSF1
colony stimulating factor 1
chr11_+_60924452 0.27 ENST00000453848.7
ENST00000544065.5
ENST00000005286.8
TMEM132A
transmembrane protein 132A
chr14_+_20999255 0.27 ENST00000554422.5
ENST00000298681.5
SLC39A2
solute carrier family 39 member 2
chr14_-_106875069 0.27 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr17_+_4951758 0.26 ENST00000518175.1
ENO3
enolase 3
chr1_+_32817442 0.26 ENST00000373476.5
ENST00000529027.5
S100PBP
S100P binding protein
chr7_-_21945866 0.26 ENST00000356195.9
ENST00000447180.5
ENST00000373934.4
ENST00000406877.8
ENST00000457951.5
CDCA7L
cell division cycle associated 7 like
chr11_-_76670737 0.26 ENST00000260061.9
ENST00000404995.5
LRRC32
leucine rich repeat containing 32
chrX_+_9786420 0.26 ENST00000380913.8
SHROOM2
shroom family member 2
chr9_-_68540879 0.26 ENST00000377311.4
TMEM252
transmembrane protein 252
chr17_+_7439504 0.25 ENST00000575331.1
ENST00000293829.9
ENSG00000272884.1
FGF11
novel transcript
fibroblast growth factor 11
chr19_+_535824 0.25 ENST00000606065.3
CDC34
cell division cycle 34, ubiqiutin conjugating enzyme
chr3_+_141487008 0.25 ENST00000286364.9
ENST00000452898.2
RASA2
RAS p21 protein activator 2
chr16_-_46831043 0.25 ENST00000565112.1
C16orf87
chromosome 16 open reading frame 87
chr19_-_38256339 0.25 ENST00000591291.5
ENST00000301242.9
PPP1R14A
protein phosphatase 1 regulatory inhibitor subunit 14A
chr20_-_44187093 0.25 ENST00000342272.3
JPH2
junctophilin 2
chrX_+_49171889 0.25 ENST00000376327.6
PLP2
proteolipid protein 2
chr16_+_70579867 0.25 ENST00000429149.6
IL34
interleukin 34
chr17_-_64263221 0.24 ENST00000258991.7
ENST00000583738.1
ENST00000584379.6
TEX2
testis expressed 2
chr2_-_74441882 0.24 ENST00000272430.10
RTKN
rhotekin
chr5_+_177304571 0.24 ENST00000503853.1
PRELID1
PRELI domain containing 1
chr1_-_47190013 0.24 ENST00000294338.7
PDZK1IP1
PDZK1 interacting protein 1
chr19_-_38256513 0.24 ENST00000347262.8
ENST00000591585.1
PPP1R14A
protein phosphatase 1 regulatory inhibitor subunit 14A
chr10_+_102394488 0.24 ENST00000369966.8
NFKB2
nuclear factor kappa B subunit 2
chrX_-_15335407 0.24 ENST00000635543.1
ENST00000542278.6
ENST00000482148.6
ENST00000333590.6
ENST00000637296.1
ENST00000634582.1
ENST00000634640.1
PIGA
phosphatidylinositol glycan anchor biosynthesis class A
chr7_+_101154981 0.24 ENST00000646560.1
AP1S1
adaptor related protein complex 1 subunit sigma 1
chr15_+_48331403 0.24 ENST00000558813.5
ENST00000331200.8
ENST00000558472.5
DUT
deoxyuridine triphosphatase
chr8_+_38820332 0.24 ENST00000518809.5
ENST00000520611.1
TACC1
transforming acidic coiled-coil containing protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0042938 dipeptide transport(GO:0042938)
0.4 1.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.4 1.3 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.4 1.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.4 1.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.3 3.7 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.3 0.9 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.3 1.1 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.3 0.8 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.2 1.0 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 1.4 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.2 0.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 0.9 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.2 0.4 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 1.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 1.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.4 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.1 1.0 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.4 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 0.4 GO:1900195 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.7 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 1.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.8 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 1.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.7 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.6 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 0.7 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 1.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.3 GO:1902567 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) negative regulation of eosinophil activation(GO:1902567) negative regulation of membrane invagination(GO:1905154) negative regulation of eosinophil migration(GO:2000417)
0.1 0.6 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.3 GO:0052255 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1 1.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.3 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 1.2 GO:1903441 protein localization to ciliary membrane(GO:1903441)
0.1 0.2 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.2 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.3 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.6 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.1 0.8 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.7 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.9 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.2 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.1 0.5 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.3 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.2 GO:0001300 chronological cell aging(GO:0001300)
0.1 1.3 GO:0032060 bleb assembly(GO:0032060)
0.1 0.5 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.2 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.6 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 2.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.0 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.7 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.9 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.1 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.7 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.4 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.2 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.0 1.1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.6 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.4 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.2 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
0.0 0.7 GO:0007620 copulation(GO:0007620)
0.0 1.2 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.4 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.9 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 1.3 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.3 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.5 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.2 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.3 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.2 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.2 GO:0060158 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.7 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 1.1 GO:0002090 regulation of receptor internalization(GO:0002090)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.0 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.4 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.5 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.8 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.0 GO:1900222 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0 1.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.3 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.2 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.2 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.0 GO:1990523 bone regeneration(GO:1990523)
0.0 0.5 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.2 GO:0048535 lymph node development(GO:0048535)
0.0 0.3 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.5 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0005610 laminin-5 complex(GO:0005610)
0.2 0.7 GO:0036117 hyaluranon cable(GO:0036117)
0.2 0.9 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.2 1.1 GO:0031523 Myb complex(GO:0031523)
0.2 0.6 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 0.8 GO:0045160 myosin I complex(GO:0045160)
0.2 1.3 GO:0000796 condensin complex(GO:0000796)
0.1 1.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.5 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 1.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.5 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 1.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.8 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 1.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.2 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.5 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 3.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.8 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.7 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 4.3 GO:0005884 actin filament(GO:0005884)
0.0 6.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.3 1.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.2 1.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 1.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 0.6 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 1.8 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.4 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.1 1.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 1.0 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 1.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.3 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.1 1.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.1 GO:0004568 chitinase activity(GO:0004568)
0.1 1.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.3 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 0.6 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 1.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 1.0 GO:0004075 biotin carboxylase activity(GO:0004075)
0.1 0.9 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.2 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.7 GO:0036042 lysophosphatidic acid binding(GO:0035727) long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.6 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.8 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.3 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.4 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.3 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 1.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.1 GO:0008940 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0035663 Toll-like receptor 4 binding(GO:0035662) Toll-like receptor 2 binding(GO:0035663)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.8 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 5.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 2.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0035473 lipase binding(GO:0035473) lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.4 GO:0019956 chemokine binding(GO:0019956)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 3.8 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.6 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 ST GAQ PATHWAY G alpha q Pathway
0.0 1.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.2 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 2.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.0 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 2.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 2.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 1.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 2.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.6 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.9 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock