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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NHLH1

Z-value: 0.91

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Transcription factors associated with NHLH1

Gene Symbol Gene ID Gene Info
NHLH1
ENSG00000171786.6 NHLH1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NHLH1hg38_v1_chr1_+_160367061_1603670780.202.8e-01Click!

Activity profile of NHLH1 motif

Sorted Z-values of NHLH1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NHLH1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_+_61508742 3.63 ENST00000378075.4
LRRC10B
leucine rich repeat containing 10B
chr16_+_67431112 3.40 ENST00000326152.6
HSD11B2
hydroxysteroid 11-beta dehydrogenase 2
chr9_-_110208156 3.09 ENST00000400613.5
C9orf152
chromosome 9 open reading frame 152
chr16_-_55833085 3.06 ENST00000360526.8
CES1
carboxylesterase 1
chr4_+_74933108 3.03 ENST00000307428.7
PARM1
prostate androgen-regulated mucin-like protein 1
chr4_+_74933095 3.02 ENST00000513238.5
PARM1
prostate androgen-regulated mucin-like protein 1
chr5_+_157266079 2.93 ENST00000616178.4
ENST00000522463.5
ENST00000435847.6
ENST00000620254.5
ENST00000521420.5
ENST00000617629.4
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr7_-_131556602 2.70 ENST00000322985.9
ENST00000378555.8
PODXL
podocalyxin like
chr12_+_101697621 2.50 ENST00000229266.8
ENST00000549872.5
CHPT1
choline phosphotransferase 1
chr13_-_36131286 2.44 ENST00000255448.8
ENST00000379892.4
DCLK1
doublecortin like kinase 1
chr2_+_85753984 2.35 ENST00000306279.4
ATOH8
atonal bHLH transcription factor 8
chr12_+_49961864 2.35 ENST00000293599.7
AQP5
aquaporin 5
chr14_-_64972143 2.21 ENST00000267512.9
RAB15
RAB15, member RAS oncogene family
chr12_-_27780236 2.14 ENST00000381273.4
MANSC4
MANSC domain containing 4
chr4_-_148442342 2.11 ENST00000358102.8
NR3C2
nuclear receptor subfamily 3 group C member 2
chr13_+_34942263 2.11 ENST00000379939.7
ENST00000400445.7
NBEA
neurobeachin
chr4_-_148442508 2.09 ENST00000625323.2
NR3C2
nuclear receptor subfamily 3 group C member 2
chr6_-_154510114 2.03 ENST00000673182.1
ENSG00000288520.1
novel protein
chr14_-_53956811 1.97 ENST00000559087.5
ENST00000245451.9
BMP4
bone morphogenetic protein 4
chr1_+_151721508 1.95 ENST00000479191.2
RIIAD1
regulatory subunit of type II PKA R-subunit domain containing 1
chr14_-_64972233 1.91 ENST00000533601.7
RAB15
RAB15, member RAS oncogene family
chr20_+_38805686 1.88 ENST00000299824.6
ENST00000373331.2
PPP1R16B
protein phosphatase 1 regulatory subunit 16B
chr2_-_229714478 1.88 ENST00000341772.5
DNER
delta/notch like EGF repeat containing
chr8_-_97277890 1.87 ENST00000322128.5
TSPYL5
TSPY like 5
chr6_-_89412219 1.81 ENST00000369415.9
RRAGD
Ras related GTP binding D
chr17_-_41124178 1.76 ENST00000394014.2
KRTAP4-12
keratin associated protein 4-12
chr20_+_59604527 1.75 ENST00000371015.6
PHACTR3
phosphatase and actin regulator 3
chrX_-_100410264 1.74 ENST00000373034.8
PCDH19
protocadherin 19
chr2_+_8682046 1.67 ENST00000331129.3
ENST00000396290.2
ID2
inhibitor of DNA binding 2
chr20_-_40689228 1.56 ENST00000373313.3
MAFB
MAF bZIP transcription factor B
chr6_-_89412069 1.48 ENST00000359203.3
RRAGD
Ras related GTP binding D
chr5_+_76819022 1.47 ENST00000296677.5
F2RL1
F2R like trypsin receptor 1
chr2_-_177618705 1.46 ENST00000355689.6
TTC30A
tetratricopeptide repeat domain 30A
chr11_-_66568524 1.44 ENST00000679160.1
ENST00000678305.1
ENST00000310325.10
ENST00000677896.1
ENST00000677587.1
ENST00000679347.1
ENST00000677005.1
ENST00000678872.1
ENST00000679024.1
ENST00000678471.1
ENST00000524994.6
CTSF
cathepsin F
chr6_-_31714062 1.41 ENST00000409239.5
LY6G6E
lymphocyte antigen 6 family member G6E
chr7_-_140062841 1.39 ENST00000263549.8
PARP12
poly(ADP-ribose) polymerase family member 12
chr2_+_197705353 1.33 ENST00000282276.8
MARS2
methionyl-tRNA synthetase 2, mitochondrial
chr6_-_154510675 1.31 ENST00000607772.6
CNKSR3
CNKSR family member 3
chr16_+_280572 1.27 ENST00000219409.8
ARHGDIG
Rho GDP dissociation inhibitor gamma
chr2_+_190408324 1.21 ENST00000417958.5
ENST00000432036.5
ENST00000392328.6
MFSD6
major facilitator superfamily domain containing 6
chr8_+_17497108 1.19 ENST00000470360.5
SLC7A2
solute carrier family 7 member 2
chr3_-_128153782 1.17 ENST00000464873.5
RUVBL1
RuvB like AAA ATPase 1
chr19_-_14206168 1.15 ENST00000361434.7
ENST00000340736.10
ADGRL1
adhesion G protein-coupled receptor L1
chr7_+_17299234 1.07 ENST00000637807.1
ENSG00000283321.1
novel protein
chr2_+_6865557 1.06 ENST00000680607.1
ENST00000680320.1
ENST00000442639.6
RSAD2
radical S-adenosyl methionine domain containing 2
chr12_+_27780224 1.05 ENST00000381271.7
KLHL42
kelch like family member 42
chr4_+_41360759 1.04 ENST00000508501.5
ENST00000512946.5
ENST00000313860.11
ENST00000512632.5
ENST00000512820.5
LIMCH1
LIM and calponin homology domains 1
chr8_+_17497078 0.99 ENST00000494857.6
ENST00000522656.5
SLC7A2
solute carrier family 7 member 2
chr15_+_50182215 0.99 ENST00000380902.8
SLC27A2
solute carrier family 27 member 2
chr4_+_88378733 0.99 ENST00000273960.7
ENST00000380265.9
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr2_+_232697299 0.98 ENST00000476995.5
ENST00000427233.5
ENST00000629305.2
ENST00000428883.5
ENST00000456491.5
ENST00000409480.5
ENST00000492910.5
ENST00000464402.5
ENST00000490612.5
ENST00000475359.6
ENST00000421433.5
ENST00000425040.5
ENST00000430720.5
ENST00000409547.5
ENST00000373563.9
ENST00000423659.5
ENST00000409196.7
ENST00000488734.5
ENST00000409451.7
ENST00000429187.5
ENST00000440945.5
GIGYF2
GRB10 interacting GYF protein 2
chr15_+_50182188 0.98 ENST00000267842.10
SLC27A2
solute carrier family 27 member 2
chr5_-_74641419 0.96 ENST00000618628.4
ENST00000510316.5
ENST00000508331.1
ENC1
ectodermal-neural cortex 1
chr22_-_31345770 0.96 ENST00000215919.3
PATZ1
POZ/BTB and AT hook containing zinc finger 1
chr8_+_74339566 0.95 ENST00000675376.1
GDAP1
ganglioside induced differentiation associated protein 1
chr6_+_125790922 0.95 ENST00000453302.5
ENST00000417494.5
ENST00000392477.7
ENST00000229634.13
NCOA7
nuclear receptor coactivator 7
chr16_+_83899079 0.94 ENST00000262430.6
MLYCD
malonyl-CoA decarboxylase
chr5_-_102296260 0.93 ENST00000310954.7
SLCO4C1
solute carrier organic anion transporter family member 4C1
chr4_+_88378842 0.93 ENST00000264346.12
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr17_-_41184895 0.92 ENST00000620667.1
ENST00000398472.2
KRTAP4-1
keratin associated protein 4-1
chr11_+_46277648 0.92 ENST00000621158.5
CREB3L1
cAMP responsive element binding protein 3 like 1
chr7_+_73433761 0.88 ENST00000344575.5
FZD9
frizzled class receptor 9
chr2_-_201451446 0.88 ENST00000332624.8
ENST00000430254.1
TRAK2
trafficking kinesin protein 2
chr13_-_36131352 0.85 ENST00000360631.8
DCLK1
doublecortin like kinase 1
chr15_-_52295792 0.84 ENST00000261839.12
MYO5C
myosin VC
chr16_+_721097 0.83 ENST00000564000.5
ENST00000219535.7
ENST00000569529.6
ANTKMT
adenine nucleotide translocase lysine methyltransferase
chr19_+_17305801 0.82 ENST00000602206.1
ENST00000252602.2
MRPL34
mitochondrial ribosomal protein L34
chr1_-_46668317 0.82 ENST00000574428.5
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr6_+_31927683 0.80 ENST00000456570.5
ENSG00000244255.5
novel complement component 2 (C2) and complement factor B (CFB) protein
chr14_-_23302823 0.79 ENST00000452015.9
PPP1R3E
protein phosphatase 1 regulatory subunit 3E
chr8_+_135457442 0.79 ENST00000355849.10
KHDRBS3
KH RNA binding domain containing, signal transduction associated 3
chr1_+_87331668 0.78 ENST00000370542.1
LMO4
LIM domain only 4
chr5_+_56815534 0.78 ENST00000399503.4
MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr15_-_26773737 0.76 ENST00000299267.8
GABRB3
gamma-aminobutyric acid type A receptor subunit beta3
chr14_-_67515429 0.76 ENST00000357461.7
ENST00000557006.6
TMEM229B
transmembrane protein 229B
chr12_+_66189208 0.75 ENST00000261233.9
IRAK3
interleukin 1 receptor associated kinase 3
chr1_-_85465147 0.75 ENST00000284031.13
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr16_+_280448 0.75 ENST00000447871.5
ARHGDIG
Rho GDP dissociation inhibitor gamma
chr5_+_51383394 0.75 ENST00000230658.12
ISL1
ISL LIM homeobox 1
chr16_+_53099100 0.73 ENST00000565832.5
CHD9
chromodomain helicase DNA binding protein 9
chr2_-_206765274 0.72 ENST00000454776.6
ENST00000449792.5
ENST00000374412.8
MDH1B
malate dehydrogenase 1B
chr1_-_177164673 0.72 ENST00000424564.2
ENST00000361833.7
ASTN1
astrotactin 1
chr3_-_12158901 0.72 ENST00000287814.5
TIMP4
TIMP metallopeptidase inhibitor 4
chr17_-_41140487 0.71 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr19_-_461007 0.71 ENST00000264554.11
SHC2
SHC adaptor protein 2
chr17_-_28951285 0.70 ENST00000577226.5
PHF12
PHD finger protein 12
chr1_-_46668394 0.69 ENST00000371937.8
ENST00000329231.8
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr12_+_108131740 0.68 ENST00000332082.8
WSCD2
WSC domain containing 2
chr2_-_177552781 0.68 ENST00000408939.4
TTC30B
tetratricopeptide repeat domain 30B
chr14_-_39432414 0.68 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr2_-_219571241 0.68 ENST00000373876.5
ENST00000603926.5
ENST00000373873.8
ENST00000289656.3
OBSL1
obscurin like cytoskeletal adaptor 1
chr16_+_19211157 0.67 ENST00000568433.1
SYT17
synaptotagmin 17
chr17_+_5078450 0.67 ENST00000318833.4
ZFP3
ZFP3 zinc finger protein
chr9_-_101594918 0.67 ENST00000374806.2
PPP3R2
protein phosphatase 3 regulatory subunit B, beta
chr14_-_88554898 0.67 ENST00000556564.6
PTPN21
protein tyrosine phosphatase non-receptor type 21
chr9_-_101594995 0.66 ENST00000636434.1
PPP3R2
protein phosphatase 3 regulatory subunit B, beta
chr13_+_98143410 0.64 ENST00000596580.2
ENST00000376581.9
FARP1
FERM, ARH/RhoGEF and pleckstrin domain protein 1
chr12_-_29783798 0.64 ENST00000552618.5
ENST00000551659.5
ENST00000539277.6
TMTC1
transmembrane O-mannosyltransferase targeting cadherins 1
chr14_-_67515153 0.64 ENST00000555994.6
TMEM229B
transmembrane protein 229B
chr7_+_17298642 0.63 ENST00000242057.9
AHR
aryl hydrocarbon receptor
chr11_+_71527267 0.63 ENST00000398536.6
KRTAP5-7
keratin associated protein 5-7
chr1_+_202348687 0.63 ENST00000608999.6
ENST00000391959.5
ENST00000480184.5
PPP1R12B
protein phosphatase 1 regulatory subunit 12B
chr12_-_89708816 0.62 ENST00000428670.8
ATP2B1
ATPase plasma membrane Ca2+ transporting 1
chr20_-_3239181 0.61 ENST00000644692.1
ENST00000642402.1
ENST00000644011.1
ENST00000647296.1
SLC4A11
solute carrier family 4 member 11
chr17_-_28951443 0.60 ENST00000268756.7
ENST00000332830.9
ENST00000584685.1
PHF12
PHD finger protein 12
chr12_+_64824602 0.59 ENST00000539867.6
ENST00000544457.1
ENST00000539120.1
TBC1D30
TBC1 domain family member 30
chr2_-_19358612 0.59 ENST00000272223.3
OSR1
odd-skipped related transcription factor 1
chr1_-_56579555 0.58 ENST00000371250.4
PLPP3
phospholipid phosphatase 3
chr12_+_41188301 0.58 ENST00000402685.7
PDZRN4
PDZ domain containing ring finger 4
chr15_-_68229658 0.57 ENST00000565471.6
ENST00000637494.1
ENST00000636314.1
ENST00000637667.1
ENST00000564752.1
ENST00000566347.5
ENST00000249806.11
ENST00000562767.2
CLN6
ENSG00000260007.3
CLN6 transmembrane ER protein
novel protein
chr14_+_73058591 0.57 ENST00000525161.5
RBM25
RNA binding motif protein 25
chr10_-_125823221 0.57 ENST00000420761.5
ENST00000368797.10
UROS
uroporphyrinogen III synthase
chr1_+_14945775 0.56 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr9_+_93184916 0.55 ENST00000448039.5
ENST00000427277.6
ENST00000297954.8
ENST00000395477.6
ENST00000432730.5
WNK2
WNK lysine deficient protein kinase 2
chr17_+_32927910 0.55 ENST00000394642.7
TMEM98
transmembrane protein 98
chr10_+_122163426 0.55 ENST00000360561.7
TACC2
transforming acidic coiled-coil containing protein 2
chr7_+_150368790 0.55 ENST00000397281.6
ENST00000444957.3
ENST00000466559.1
ENST00000475514.5
ENST00000482680.1
ENST00000488943.1
ENST00000489432.7
ENST00000518514.1
ENST00000478789.5
REPIN1
ZNF775
replication initiator 1
zinc finger protein 775
chr17_+_42536510 0.55 ENST00000585572.1
ENST00000586516.5
ENST00000591587.1
ENSG00000266929.1
NAGLU
novel transcript
N-acetyl-alpha-glucosaminidase
chr7_+_30852273 0.54 ENST00000509504.2
ENSG00000250424.4
novel protein, MINDY4 and AQP1 readthrough
chr19_+_3094348 0.54 ENST00000078429.9
GNA11
G protein subunit alpha 11
chr12_-_79690814 0.54 ENST00000548426.1
PAWR
pro-apoptotic WT1 regulator
chr14_-_23352741 0.54 ENST00000354772.9
SLC22A17
solute carrier family 22 member 17
chr12_+_109713817 0.54 ENST00000538780.2
FAM222A
family with sequence similarity 222 member A
chr10_+_122163672 0.54 ENST00000369004.7
ENST00000260733.7
TACC2
transforming acidic coiled-coil containing protein 2
chr1_-_37808168 0.54 ENST00000373044.3
YRDC
yrdC N6-threonylcarbamoyltransferase domain containing
chr1_-_91886144 0.53 ENST00000212355.9
TGFBR3
transforming growth factor beta receptor 3
chr17_-_41168219 0.53 ENST00000391356.4
KRTAP4-3
keratin associated protein 4-3
chr1_-_182391363 0.52 ENST00000417584.6
GLUL
glutamate-ammonia ligase
chr15_-_60592507 0.52 ENST00000449337.6
RORA
RAR related orphan receptor A
chr1_-_182391783 0.52 ENST00000331872.11
ENST00000339526.8
GLUL
glutamate-ammonia ligase
chr5_-_95284535 0.52 ENST00000515393.5
MCTP1
multiple C2 and transmembrane domain containing 1
chr8_+_97775775 0.51 ENST00000521545.7
LAPTM4B
lysosomal protein transmembrane 4 beta
chr1_-_48472166 0.51 ENST00000371847.8
ENST00000396199.7
SPATA6
spermatogenesis associated 6
chr10_+_122163590 0.51 ENST00000368999.5
TACC2
transforming acidic coiled-coil containing protein 2
chr2_-_86337654 0.51 ENST00000165698.9
REEP1
receptor accessory protein 1
chr2_-_86337617 0.51 ENST00000538924.7
ENST00000535845.6
REEP1
receptor accessory protein 1
chr22_+_44677044 0.50 ENST00000006251.11
PRR5
proline rich 5
chr14_+_73058521 0.50 ENST00000527432.5
ENST00000531500.5
ENST00000261973.12
ENST00000525321.5
ENST00000526754.5
RBM25
RNA binding motif protein 25
chr6_-_166627244 0.50 ENST00000265678.9
RPS6KA2
ribosomal protein S6 kinase A2
chr19_-_47231191 0.49 ENST00000439096.3
BBC3
BCL2 binding component 3
chr17_-_17206264 0.49 ENST00000321560.4
PLD6
phospholipase D family member 6
chr17_+_75516514 0.49 ENST00000333213.11
ENST00000545228.3
ENST00000680999.1
TSEN54
tRNA splicing endonuclease subunit 54
chr7_+_129144691 0.49 ENST00000486685.3
TSPAN33
tetraspanin 33
chr11_-_695215 0.49 ENST00000382409.4
DEAF1
DEAF1 transcription factor
chr13_+_77697679 0.49 ENST00000418532.6
SLAIN1
SLAIN motif family member 1
chr1_-_11047225 0.48 ENST00000400898.3
ENST00000400897.8
MASP2
mannan binding lectin serine peptidase 2
chr5_-_2751648 0.48 ENST00000382611.10
IRX2
iroquois homeobox 2
chr9_+_2017383 0.48 ENST00000382194.6
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_+_104801082 0.48 ENST00000342537.8
ZBTB42
zinc finger and BTB domain containing 42
chr21_+_33324954 0.48 ENST00000270139.8
ENST00000442071.2
ENST00000652513.1
ENST00000652601.1
IFNAR1
interferon alpha and beta receptor subunit 1
chr17_+_42536226 0.48 ENST00000225927.7
NAGLU
N-acetyl-alpha-glucosaminidase
chr12_+_6946468 0.48 ENST00000543115.5
ENST00000399448.5
PTPN6
protein tyrosine phosphatase non-receptor type 6
chr1_+_89524871 0.48 ENST00000639264.1
LRRC8B
leucine rich repeat containing 8 VRAC subunit B
chr6_+_71886900 0.47 ENST00000517960.5
ENST00000518273.5
ENST00000522291.5
ENST00000521978.5
ENST00000520567.5
ENST00000264839.11
RIMS1
regulating synaptic membrane exocytosis 1
chr9_+_97853217 0.47 ENST00000375123.5
FOXE1
forkhead box E1
chr7_+_91940970 0.47 ENST00000359028.7
AKAP9
A-kinase anchoring protein 9
chr12_-_42483958 0.47 ENST00000548696.6
ENST00000552240.6
PRICKLE1
prickle planar cell polarity protein 1
chr17_+_57085092 0.47 ENST00000575322.1
ENST00000337714.8
AKAP1
A-kinase anchoring protein 1
chr15_-_101724416 0.47 ENST00000615656.1
ENST00000335968.8
TARS3
threonyl-tRNA synthetase 3
chr19_-_46634685 0.46 ENST00000300873.4
GNG8
G protein subunit gamma 8
chr7_+_102433519 0.46 ENST00000356387.6
ENST00000478730.7
ENST00000495936.7
ENST00000611770.5
ENST00000403646.8
ORAI2
ORAI calcium release-activated calcium modulator 2
chr18_+_58255433 0.46 ENST00000635997.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr1_-_40317266 0.46 ENST00000372736.3
ENST00000372748.8
COL9A2
collagen type IX alpha 2 chain
chr16_-_29899245 0.46 ENST00000537485.5
SEZ6L2
seizure related 6 homolog like 2
chr12_-_111369088 0.46 ENST00000683047.1
ENST00000547710.1
ENST00000549321.1
ENST00000361483.4
PHETA1
PH domain containing endocytic trafficking adaptor 1
chr17_-_42194459 0.46 ENST00000593209.5
ENST00000588352.5
ENST00000587427.6
ENST00000414034.7
ENST00000590249.5
ENST00000428494.6
GHDC
GH3 domain containing
chr16_-_29899043 0.45 ENST00000346932.9
ENST00000350527.7
ENST00000568380.1
SEZ6L2
seizure related 6 homolog like 2
chr19_-_49072699 0.45 ENST00000221444.2
KCNA7
potassium voltage-gated channel subfamily A member 7
chr9_-_123268538 0.45 ENST00000360998.3
ENST00000348403.10
STRBP
spermatid perinuclear RNA binding protein
chr17_+_32928126 0.45 ENST00000579849.6
ENST00000578289.5
ENST00000439138.5
TMEM98
transmembrane protein 98
chr15_+_43510945 0.45 ENST00000382031.5
MAP1A
microtubule associated protein 1A
chr11_+_72227881 0.45 ENST00000538751.5
ENST00000541756.5
INPPL1
inositol polyphosphate phosphatase like 1
chr2_-_219571529 0.44 ENST00000404537.6
OBSL1
obscurin like cytoskeletal adaptor 1
chr12_+_66189254 0.44 ENST00000457197.2
IRAK3
interleukin 1 receptor associated kinase 3
chr18_-_55586092 0.44 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
TCF4
transcription factor 4
chr12_+_122021850 0.44 ENST00000261822.5
BCL7A
BAF chromatin remodeling complex subunit BCL7A
chr17_-_58529344 0.44 ENST00000317268.7
SEPTIN4
septin 4
chr12_-_42484298 0.43 ENST00000640055.1
ENST00000639566.1
ENST00000455697.6
ENST00000639589.1
PRICKLE1
prickle planar cell polarity protein 1
chr17_-_58529277 0.43 ENST00000579371.5
SEPTIN4
septin 4
chr14_+_104865256 0.43 ENST00000414716.8
ENST00000556508.5
ENST00000453495.2
CEP170B
centrosomal protein 170B
chr17_-_41160746 0.43 ENST00000390661.5
KRTAP4-4
keratin associated protein 4-4
chr10_-_122845850 0.43 ENST00000392790.6
CUZD1
CUB and zona pellucida like domains 1
chr17_-_58529303 0.43 ENST00000580844.5
SEPTIN4
septin 4
chr12_-_114683590 0.42 ENST00000257566.7
TBX3
T-box transcription factor 3
chr10_-_125823089 0.42 ENST00000368774.1
ENST00000368778.7
ENST00000649536.1
UROS
uroporphyrinogen III synthase
chr1_+_89524819 0.42 ENST00000439853.6
ENST00000330947.7
ENST00000449440.5
ENST00000640258.1
LRRC8B
leucine rich repeat containing 8 VRAC subunit B
chr1_+_51236252 0.42 ENST00000242719.4
RNF11
ring finger protein 11
chr7_-_27130733 0.42 ENST00000428284.2
ENST00000360046.10
ENST00000610970.1
HOXA4
homeobox A4
chr14_-_92040027 0.42 ENST00000267622.8
TRIP11
thyroid hormone receptor interactor 11
chr20_-_17682060 0.42 ENST00000455029.3
RRBP1
ribosome binding protein 1
chr16_+_22814154 0.42 ENST00000261374.4
HS3ST2
heparan sulfate-glucosamine 3-sulfotransferase 2
chr19_-_3061403 0.42 ENST00000586839.1
TLE5
TLE family member 5, transcriptional modulator
chr19_+_14433284 0.41 ENST00000242783.11
PKN1
protein kinase N1
chr12_+_53423849 0.41 ENST00000257863.9
ENST00000550311.5
ENST00000379791.7
AMHR2
anti-Mullerian hormone receptor type 2
chr16_+_25216943 0.41 ENST00000219660.6
AQP8
aquaporin 8
chr14_-_24442765 0.41 ENST00000555365.5
ENST00000399395.8
ENST00000553930.5
SDR39U1
short chain dehydrogenase/reductase family 39U member 1
chr1_-_27366917 0.41 ENST00000357582.3
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr17_-_8799365 0.41 ENST00000329805.6
MFSD6L
major facilitator superfamily domain containing 6 like
chr10_-_132307935 0.40 ENST00000298630.8
STK32C
serine/threonine kinase 32C
chr9_-_34376878 0.40 ENST00000297625.8
MYORG
myogenesis regulating glycosidase (putative)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.7 2.2 GO:1903400 L-arginine transmembrane transport(GO:1903400)
0.7 2.7 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.7 2.0 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.6 1.9 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.6 2.5 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.6 0.6 GO:0061227 intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.6 1.7 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.5 2.0 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.4 1.2 GO:0010933 macrophage tolerance induction(GO:0010931) regulation of macrophage tolerance induction(GO:0010932) positive regulation of macrophage tolerance induction(GO:0010933)
0.4 1.6 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.4 1.5 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.4 3.3 GO:0071233 cellular response to leucine(GO:0071233) cellular response to leucine starvation(GO:1990253)
0.3 2.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 0.9 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.3 0.9 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.3 1.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 0.7 GO:0060913 visceral motor neuron differentiation(GO:0021524) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.2 1.0 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.2 0.9 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2 0.6 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.2 0.9 GO:2000691 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 1.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 0.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 1.1 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.2 3.4 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.2 2.6 GO:0046541 saliva secretion(GO:0046541)
0.2 0.5 GO:0008358 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.2 0.8 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.4 GO:0060931 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931) His-Purkinje system cell differentiation(GO:0060932)
0.1 0.5 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.9 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.5 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.4 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.3 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 0.5 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 5.4 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 1.9 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.4 GO:0072302 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.3 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.1 0.3 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 0.4 GO:1990637 response to prolactin(GO:1990637)
0.1 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 2.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 1.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.4 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1 0.5 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.2 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 0.2 GO:0045632 negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.1 0.2 GO:0018307 enzyme active site formation(GO:0018307)
0.1 0.3 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.6 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 0.4 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.3 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.9 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.6 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.2 GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.2 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.1 0.2 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.6 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.5 GO:0019236 response to pheromone(GO:0019236)
0.1 0.4 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.3 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.2 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.9 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.2 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.4 GO:1902075 cellular response to salt(GO:1902075)
0.1 1.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 1.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.3 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.1 3.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.7 GO:0006108 malate metabolic process(GO:0006108)
0.1 1.1 GO:0000052 citrulline metabolic process(GO:0000052)
0.1 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.4 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 4.4 GO:1903307 positive regulation of regulated secretory pathway(GO:1903307)
0.1 0.5 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.2 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.1 0.9 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.9 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.2 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1 0.1 GO:1903998 regulation of eating behavior(GO:1903998)
0.1 0.2 GO:1901859 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) negative regulation of ATP biosynthetic process(GO:2001170)
0.0 0.4 GO:0072564 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 1.4 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.2 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.3 GO:0072553 terminal button organization(GO:0072553)
0.0 0.2 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.2 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.6 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.3 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.5 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.1 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.1 GO:0010957 negative regulation of vitamin D biosynthetic process(GO:0010957)
0.0 1.9 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0034699 response to luteinizing hormone(GO:0034699)
0.0 0.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.9 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 1.0 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 1.0 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 1.1 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0 1.2 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.6 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.5 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.3 GO:0003360 brainstem development(GO:0003360)
0.0 0.3 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.0 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:0001967 suckling behavior(GO:0001967)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 1.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.4 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.3 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.8 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 1.7 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.3 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 1.0 GO:0042044 fluid transport(GO:0042044)
0.0 0.1 GO:0021678 third ventricle development(GO:0021678)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.4 GO:0051315 protein localization to kinetochore(GO:0034501) attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.7 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0048050 sequestering of BMP in extracellular matrix(GO:0035582) post-embryonic eye morphogenesis(GO:0048050)
0.0 1.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.4 GO:0003016 respiratory system process(GO:0003016)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.5 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.3 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.5 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.1 GO:1901297 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 1.0 GO:0050879 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.0 0.3 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.4 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.3 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.5 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.0 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 3.4 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.0 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.5 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.0 GO:2000845 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 0.8 GO:0097224 sperm connecting piece(GO:0097224)
0.2 1.3 GO:1990393 3M complex(GO:1990393)
0.2 0.6 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.2 2.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.9 GO:0032044 DSIF complex(GO:0032044)
0.1 1.0 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.5 GO:0044307 dendritic branch(GO:0044307)
0.1 1.2 GO:0097255 R2TP complex(GO:0097255)
0.1 0.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.5 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.4 GO:0002081 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.1 0.2 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 2.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.2 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 1.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.3 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.3 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 2.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.4 GO:0032010 phagolysosome(GO:0032010)
0.0 1.2 GO:0097386 glial cell projection(GO:0097386)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.5 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 1.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 7.5 GO:0005770 late endosome(GO:0005770)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.8 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.4 GO:0000786 nucleosome(GO:0000786)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.7 2.2 GO:0005292 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.6 2.5 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.6 3.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.3 1.0 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 1.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 0.6 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 1.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 2.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 1.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 1.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 3.0 GO:0015250 water channel activity(GO:0015250)
0.2 2.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.4 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.5 GO:0001855 complement component C4b binding(GO:0001855)
0.1 0.7 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 2.0 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.3 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1 0.4 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.1 0.6 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.5 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 0.3 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.1 0.8 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.3 GO:0009032 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
0.1 1.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.3 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 1.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.4 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.4 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.8 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.2 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 1.8 GO:0005112 Notch binding(GO:0005112)
0.1 0.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.8 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647) nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.6 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.4 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.2 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 1.0 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 1.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 1.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 1.0 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.2 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.3 GO:0004645 phosphorylase activity(GO:0004645)
0.0 4.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 3.0 GO:0019003 GDP binding(GO:0019003)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 2.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0034618 arginine binding(GO:0034618)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 1.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.4 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 5.0 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE binding(GO:0019863)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.0 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.4 GO:0051393 alpha-actinin binding(GO:0051393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 5.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 1.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 2.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 5.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 2.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 2.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 4.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 1.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 1.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 1.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.7 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.1 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks