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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NKX2-3

Z-value: 1.14

Motif logo

Transcription factors associated with NKX2-3

Gene Symbol Gene ID Gene Info
ENSG00000119919.11 NKX2-3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-3hg38_v1_chr10_+_99532927_995329530.019.6e-01Click!

Activity profile of NKX2-3 motif

Sorted Z-values of NKX2-3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_151025343 10.92 ENST00000521632.1
glutathione peroxidase 3
chr12_+_8822610 6.55 ENST00000299698.12
alpha-2-macroglobulin like 1
chr19_-_51002527 5.74 ENST00000595238.1
ENST00000600767.5
kallikrein related peptidase 8
chr1_-_205422050 5.43 ENST00000367153.9
LEM domain containing 1
chr19_-_51001668 4.15 ENST00000347619.8
ENST00000291726.11
ENST00000320838.9
kallikrein related peptidase 8
chr5_-_111512473 4.09 ENST00000296632.8
ENST00000512160.5
ENST00000509887.5
StAR related lipid transfer domain containing 4
chr11_+_35189869 4.00 ENST00000525688.5
ENST00000278385.10
ENST00000533222.5
CD44 molecule (Indian blood group)
chr3_-_111595339 3.81 ENST00000317012.5
zinc finger BED-type containing 2
chr2_-_31217511 3.65 ENST00000403897.4
calpain 14
chr19_-_18941184 3.51 ENST00000594794.5
ENST00000392351.8
ENST00000596482.5
homer scaffold protein 3
chr19_-_14778552 3.22 ENST00000315576.8
adhesion G protein-coupled receptor E2
chr3_+_102099244 3.15 ENST00000491959.5
zona pellucida like domain containing 1
chr12_-_119877270 3.12 ENST00000261833.11
ENST00000612548.4
citron rho-interacting serine/threonine kinase
chr17_+_72121012 3.02 ENST00000245479.3
SRY-box transcription factor 9
chr3_+_98763331 2.97 ENST00000485391.5
ENST00000492254.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr5_+_151020438 2.89 ENST00000622181.4
ENST00000614343.4
ENST00000388825.9
ENST00000521650.5
ENST00000517973.1
glutathione peroxidase 3
chr17_-_78874038 2.68 ENST00000586057.5
TIMP metallopeptidase inhibitor 2
chr17_-_78874140 2.67 ENST00000585421.5
TIMP metallopeptidase inhibitor 2
chr19_+_44905785 2.49 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
apolipoprotein E
chr11_-_102798148 2.39 ENST00000315274.7
matrix metallopeptidase 1
chr12_-_122703346 2.17 ENST00000328880.6
hydroxycarboxylic acid receptor 2
chr4_-_67883987 2.16 ENST00000283916.11
transmembrane serine protease 11D
chr1_-_162412117 2.13 ENST00000367929.3
SH2 domain containing 1B
chr11_+_35189964 2.12 ENST00000524922.1
CD44 molecule (Indian blood group)
chr13_+_48653921 2.09 ENST00000682523.1
cysteinyl leukotriene receptor 2
chr17_-_8152380 2.00 ENST00000317276.9
period circadian regulator 1
chr6_-_144008364 1.98 ENST00000625622.2
PLAG1 like zinc finger 1
chr6_+_32154010 1.98 ENST00000375137.6
palmitoyl-protein thioesterase 2
chr15_+_40382715 1.98 ENST00000416151.6
ENST00000249776.12
kinetochore localized astrin (SPAG5) binding protein
chr14_-_67412112 1.91 ENST00000216446.9
pleckstrin 2
chr13_-_30306997 1.89 ENST00000380617.7
ENST00000441394.1
katanin catalytic subunit A1 like 1
chr4_-_39032343 1.89 ENST00000381938.4
transmembrane protein 156
chr12_-_122716790 1.79 ENST00000528880.3
hydroxycarboxylic acid receptor 3
chr15_+_40382764 1.79 ENST00000448395.6
kinetochore localized astrin (SPAG5) binding protein
chr2_+_172556039 1.73 ENST00000410055.5
ENST00000282077.8
pyruvate dehydrogenase kinase 1
chr16_+_11249617 1.72 ENST00000572173.1
RecQ mediated genome instability 2
chr6_-_144008396 1.72 ENST00000354765.6
ENST00000416623.5
ENST00000649211.1
PLAG1 like zinc finger 1
chr18_+_63777773 1.66 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr14_-_91253925 1.63 ENST00000531499.2
G protein-coupled receptor 68
chr6_-_11382247 1.57 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
neural precursor cell expressed, developmentally down-regulated 9
chr16_-_90019821 1.54 ENST00000568838.2
dysbindin domain containing 1
chr13_-_44161257 1.51 ENST00000400419.2
small integral membrane protein 2
chr18_-_12656716 1.49 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
spire type actin nucleation factor 1
chr14_-_102362714 1.47 ENST00000536961.6
ENST00000541568.6
ENST00000216756.11
cyclin dependent kinase 2 interacting protein
chr22_-_37188281 1.46 ENST00000397110.6
C1q and TNF related 6
chr3_+_156674579 1.43 ENST00000295924.12
TCDD inducible poly(ADP-ribose) polymerase
chr7_+_134745460 1.43 ENST00000436461.6
caldesmon 1
chr17_+_28335571 1.40 ENST00000544907.6
TNF alpha induced protein 1
chr9_-_111036207 1.40 ENST00000541779.5
lysophosphatidic acid receptor 1
chr5_+_150671588 1.40 ENST00000523553.1
myozenin 3
chr4_-_39032922 1.36 ENST00000344606.6
transmembrane protein 156
chr11_+_61248122 1.36 ENST00000451616.6
pepsinogen A5
chr14_-_49688201 1.35 ENST00000553805.2
ENST00000554396.5
ENST00000216367.10
DNA polymerase epsilon 2, accessory subunit
chr9_+_136952256 1.35 ENST00000371633.8
lipocalin 12
chr1_-_79006773 1.32 ENST00000671209.1
adhesion G protein-coupled receptor L4
chr17_+_28335718 1.32 ENST00000226225.7
TNF alpha induced protein 1
chr22_+_38057371 1.31 ENST00000437453.5
ENST00000356976.8
protein interacting with PRKCA 1
chr8_+_12104389 1.29 ENST00000400085.7
zinc finger protein 705D
chr1_-_79006680 1.29 ENST00000370742.4
ENST00000656841.1
adhesion G protein-coupled receptor L4
chr6_+_32153441 1.26 ENST00000414204.5
ENST00000361568.6
ENST00000395523.5
palmitoyl-protein thioesterase 2
chr2_-_171434763 1.24 ENST00000442778.5
ENST00000453846.5
ENST00000612742.5
methyltransferase like 8
chr20_-_23988779 1.21 ENST00000335694.4
gamma-glutamyltransferase light chain 1
chr3_+_155083523 1.21 ENST00000680057.1
membrane metalloendopeptidase
chr2_-_131492380 1.21 ENST00000309451.7
mitotic spindle organizing protein 2A
chr1_+_155308748 1.19 ENST00000611010.4
ENST00000447866.5
ENST00000368356.9
ENST00000467076.5
ENST00000491013.5
ENST00000356657.10
farnesyl diphosphate synthase
chr11_+_124865425 1.19 ENST00000397801.6
roundabout guidance receptor 3
chr8_-_48921419 1.18 ENST00000020945.4
snail family transcriptional repressor 2
chr13_-_23433676 1.14 ENST00000682547.1
ENST00000455470.6
ENST00000382292.9
sacsin molecular chaperone
chr9_-_134917872 1.11 ENST00000616356.4
ENST00000371806.4
ficolin 1
chr17_-_8156320 1.11 ENST00000584202.1
ENST00000354903.9
ENST00000577253.5
period circadian regulator 1
chr17_-_82840010 1.08 ENST00000269394.4
ENST00000572562.1
zinc finger protein 750
chr3_+_155083889 1.07 ENST00000680282.1
membrane metalloendopeptidase
chr18_+_24460655 1.07 ENST00000426880.2
histamine receptor H4
chr13_-_23433735 1.07 ENST00000423156.2
ENST00000683210.1
ENST00000682775.1
ENST00000684497.1
ENST00000682944.1
ENST00000683489.1
ENST00000684385.1
ENST00000683680.1
sacsin molecular chaperone
chr12_+_100573642 1.06 ENST00000266754.9
ENST00000547754.6
growth arrest specific 2 like 3
chr12_-_84911178 1.06 ENST00000681688.1
solute carrier family 6 member 15
chr2_+_200305873 1.03 ENST00000439084.5
ENST00000409718.5
spermatogenesis associated serine rich 2 like
chr2_+_190137760 1.02 ENST00000396974.2
chromosome 2 open reading frame 88
chr10_-_75109085 1.02 ENST00000607131.5
dual specificity phosphatase 13
chr1_-_155910881 1.01 ENST00000609492.1
ENST00000368322.7
Ras like without CAAX 1
chr2_+_130181662 1.01 ENST00000425361.5
ENST00000457492.5
mitotic spindle organizing protein 2B
chr2_-_130181542 1.00 ENST00000441135.1
ENST00000680679.1
ENST00000680401.1
ENST00000351288.10
ENST00000680298.1
ENST00000431183.6
sphingomyelin phosphodiesterase 4
chr10_-_102502702 0.99 ENST00000369905.9
actin related protein 1A
chr17_-_15566276 0.98 ENST00000630868.1
CMT1A duplicated region transcript 1
chr15_+_90868580 0.98 ENST00000268171.8
furin, paired basic amino acid cleaving enzyme
chr17_-_3063607 0.96 ENST00000575751.1
olfactory receptor family 1 subfamily D member 5
chr10_+_99659430 0.94 ENST00000370489.5
ectonucleoside triphosphate diphosphohydrolase 7
chr3_+_114056728 0.91 ENST00000485050.5
ENST00000281273.8
ENST00000479882.5
ENST00000493014.1
queuine tRNA-ribosyltransferase accessory subunit 2
chr12_+_93569814 0.91 ENST00000340600.6
suppressor of cytokine signaling 2
chr22_-_37188233 0.90 ENST00000434784.1
ENST00000337843.7
C1q and TNF related 6
chr14_+_94081278 0.89 ENST00000555523.6
ENST00000393115.7
ENST00000554166.5
ENST00000556381.5
ENST00000553664.1
ENST00000555341.5
ENST00000557218.5
ENST00000554544.5
ENST00000557066.5
interferon alpha inducible protein 27 like 1
chrX_+_38006551 0.88 ENST00000297875.7
synaptotagmin like 5
chr4_-_89836213 0.86 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chr5_-_176416222 0.85 ENST00000508425.5
clathrin light chain B
chr18_+_24460630 0.84 ENST00000256906.5
histamine receptor H4
chr19_+_39125769 0.83 ENST00000602004.1
ENST00000599470.5
ENST00000321944.8
ENST00000593480.5
ENST00000358301.7
ENST00000593690.5
ENST00000599386.5
p21 (RAC1) activated kinase 4
chr10_+_3104676 0.83 ENST00000415005.6
ENST00000468050.1
phosphofructokinase, platelet
chr10_-_75109172 0.82 ENST00000372700.7
ENST00000473072.2
ENST00000491677.6
ENST00000372702.7
dual specificity phosphatase 13
chr10_+_103245887 0.81 ENST00000441178.2
ribulose-5-phosphate-3-epimerase like 1
chr5_-_115841548 0.80 ENST00000509910.2
ENST00000500945.2
autophagy related 12
chr3_+_57060658 0.80 ENST00000334325.2
spermatogenesis associated 12
chr17_+_77405070 0.79 ENST00000585930.5
septin 9
chr1_+_65147657 0.78 ENST00000546702.5
adenylate kinase 4
chr18_+_46104344 0.78 ENST00000592471.1
ENST00000282058.11
ENST00000585518.5
HAUS augmin like complex subunit 1
chr22_+_38057200 0.77 ENST00000404072.7
ENST00000424694.5
protein interacting with PRKCA 1
chr1_+_112674416 0.77 ENST00000413052.6
ENST00000369645.5
Mov10 RISC complex RNA helicase
chr13_+_31739520 0.76 ENST00000298386.7
relaxin family peptide receptor 2
chr6_-_151452018 0.75 ENST00000491268.2
required for meiotic nuclear division 1 homolog
chr6_-_151452096 0.75 ENST00000444024.3
ENST00000682641.1
ENST00000682299.1
ENST00000622845.5
required for meiotic nuclear division 1 homolog
chr19_-_50637939 0.75 ENST00000338916.8
synaptotagmin 3
chr2_-_187554351 0.74 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
tissue factor pathway inhibitor
chr1_-_197067234 0.72 ENST00000367412.2
coagulation factor XIII B chain
chr19_+_55676621 0.72 ENST00000411543.6
epsin 1
chr13_+_31739542 0.71 ENST00000380314.2
relaxin family peptide receptor 2
chr4_+_87832917 0.70 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr18_-_66604076 0.70 ENST00000540086.5
ENST00000580157.2
ENST00000262150.7
cadherin 19
chr4_+_94455245 0.69 ENST00000508216.5
ENST00000514743.5
PDZ and LIM domain 5
chr10_+_69278492 0.69 ENST00000643399.2
hexokinase 1
chr3_-_42875871 0.69 ENST00000316161.6
ENST00000437102.1
cytochrome P450 family 8 subfamily B member 1
chr11_+_120325283 0.68 ENST00000314475.6
ENST00000375095.3
ENST00000529187.1
TLC domain containing 5
chr19_+_15728024 0.67 ENST00000305899.5
olfactory receptor family 10 subfamily H member 2
chr20_+_59835853 0.65 ENST00000492611.5
phosphatase and actin regulator 3
chr8_+_41529242 0.64 ENST00000523277.6
ENST00000276533.4
GINS complex subunit 4
chr5_+_108747879 0.64 ENST00000281092.9
FER tyrosine kinase
chr19_+_41376499 0.64 ENST00000392002.7
transmembrane protein 91
chr10_+_97572771 0.63 ENST00000370655.6
ENST00000455090.1
ankyrin repeat domain 2
chr1_-_33431079 0.63 ENST00000683057.1
polyhomeotic homolog 2
chr7_-_87713287 0.62 ENST00000416177.1
ENST00000265724.8
ENST00000543898.5
ATP binding cassette subfamily B member 1
chrX_-_107118783 0.62 ENST00000372487.5
ENST00000372479.7
RNA binding motif protein 41
chr11_+_10305065 0.62 ENST00000534464.1
ENST00000278175.10
ENST00000530439.1
ENST00000524948.5
ENST00000528655.5
ENST00000526492.4
ENST00000525063.2
adrenomedullin
chr10_-_102502669 0.61 ENST00000487599.1
actin related protein 1A
chr10_+_97572493 0.61 ENST00000307518.9
ENST00000298808.9
ankyrin repeat domain 2
chr3_+_184174846 0.61 ENST00000427072.5
ENST00000411763.6
ENST00000292807.9
ENST00000448139.5
ENST00000455925.1
adaptor related protein complex 2 subunit mu 1
chr10_-_72217126 0.61 ENST00000317126.8
activating signal cointegrator 1 complex subunit 1
chr14_-_75176593 0.60 ENST00000303575.9
transmembrane p24 trafficking protein 10
chr8_-_123737378 0.58 ENST00000419625.6
ENST00000262219.10
annexin A13
chr4_+_143381939 0.58 ENST00000505913.5
GRB2 associated binding protein 1
chr3_-_122514876 0.58 ENST00000493510.1
ENST00000476916.5
ENST00000344337.11
ENST00000465882.5
karyopherin subunit alpha 1
chr14_-_92748570 0.58 ENST00000553918.1
ENST00000555699.5
ENST00000334869.9
ENST00000553802.5
ENST00000554397.5
ENST00000554919.5
ENST00000554080.5
ENST00000553371.1
ENST00000557434.5
ENST00000393218.6
legumain
chr7_-_111562455 0.57 ENST00000452895.5
ENST00000405709.7
ENST00000452753.1
ENST00000331762.7
inner mitochondrial membrane peptidase subunit 2
chr6_+_31586269 0.57 ENST00000438075.7
leukocyte specific transcript 1
chr19_+_33374312 0.57 ENST00000585933.2
CCAAT enhancer binding protein gamma
chr12_+_49367364 0.56 ENST00000549298.5
spermatogenesis associated serine rich 2
chr9_-_39239174 0.56 ENST00000358144.6
contactin associated protein family member 3
chr13_-_46182136 0.56 ENST00000323076.7
lymphocyte cytosolic protein 1
chr18_-_36122110 0.56 ENST00000586829.1
solute carrier family 39 member 6
chr1_+_65147514 0.56 ENST00000545314.5
adenylate kinase 4
chr19_-_1401487 0.56 ENST00000640762.1
ENST00000252288.8
ENST00000447102.8
guanidinoacetate N-methyltransferase
chr3_+_63443306 0.55 ENST00000472899.5
ENST00000479198.5
ENST00000460711.5
ENST00000465156.1
synaptoporin
chr4_-_89837076 0.55 ENST00000506691.1
synuclein alpha
chr1_-_240612147 0.55 ENST00000318160.5
gremlin 2, DAN family BMP antagonist
chr2_+_190180447 0.54 ENST00000409870.1
chromosome 2 open reading frame 88
chr19_-_45785659 0.54 ENST00000537879.1
ENST00000596586.5
ENST00000595946.1
DM1 locus, WD repeat containing
novel protein
chr1_+_184051643 0.54 ENST00000423085.7
ENST00000361641.6
tRNA splicing endonuclease subunit 15
chr1_+_109548567 0.54 ENST00000369851.7
G protein subunit alpha i3
chr6_-_26216673 0.54 ENST00000541790.3
H2B clustered histone 8
chr12_+_122980060 0.53 ENST00000543566.6
ENST00000453766.7
ENST00000392435.7
ENST00000413381.6
ENST00000426960.6
ADP ribosylation factor like GTPase 6 interacting protein 4
chr16_+_69424634 0.53 ENST00000515314.6
ENST00000561792.6
ENST00000568237.1
cytochrome b5 type B
chr2_+_113406368 0.53 ENST00000453673.3
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr6_+_143864458 0.53 ENST00000237275.9
zinc finger C2HC-type containing 1B
chrX_-_49264668 0.53 ENST00000455775.7
ENST00000652559.1
ENST00000376207.10
ENST00000557224.6
ENST00000684155.1
ENST00000376199.7
forkhead box P3
chr17_+_68525795 0.53 ENST00000592800.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr8_-_92017637 0.52 ENST00000422361.6
RUNX1 partner transcriptional co-repressor 1
chr1_-_114153863 0.52 ENST00000610222.3
ENST00000369547.6
ENST00000641643.2
synaptotagmin 6
chr16_-_18900044 0.51 ENST00000565224.5
ENST00000330588.4
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr8_+_32721823 0.50 ENST00000539990.3
ENST00000519240.5
neuregulin 1
chrX_+_41688967 0.50 ENST00000378142.9
G protein-coupled receptor 34
chr12_+_122980486 0.50 ENST00000454885.6
ADP ribosylation factor like GTPase 6 interacting protein 4
chr20_-_50153637 0.50 ENST00000341698.2
ENST00000371652.9
ENST00000371650.9
PEDS1-UBE2V1 readthrough
plasmanylethanolamine desaturase 1
chr12_+_49367440 0.50 ENST00000552918.6
ENST00000553127.5
ENST00000321898.10
spermatogenesis associated serine rich 2
chr3_-_101320558 0.48 ENST00000193391.8
interphotoreceptor matrix proteoglycan 2
chr3_+_183253230 0.48 ENST00000326505.4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr19_-_18323100 0.48 ENST00000594828.7
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr16_-_11269320 0.48 ENST00000312693.4
transition protein 2
chr5_-_152405277 0.48 ENST00000255262.4
neuromedin U receptor 2
chr19_-_38253238 0.47 ENST00000587515.5
protein phosphatase 1 regulatory inhibitor subunit 14A
chr12_-_120194702 0.47 ENST00000300648.7
GCN1 activator of EIF2AK4
chr6_+_31587002 0.47 ENST00000376090.6
leukocyte specific transcript 1
chrX_+_41689006 0.46 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
G protein-coupled receptor 34
chr17_+_60149966 0.46 ENST00000300900.9
carbonic anhydrase 4
chr2_-_36598140 0.46 ENST00000405912.8
ENST00000379245.8
fasciculation and elongation protein zeta 2
chr4_+_25160631 0.46 ENST00000510415.1
ENST00000507794.2
ENST00000512921.4
SEPSECS antisense RNA 1 (head to head)
phosphatidylinositol 4-kinase type 2 beta
chr11_+_66593171 0.46 ENST00000533244.6
copper chaperone for superoxide dismutase
chr19_+_41376692 0.46 ENST00000447302.6
ENST00000544232.5
ENST00000542945.5
ENST00000540732.3
transmembrane protein 91
novel protein
chr10_-_77637789 0.46 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
potassium calcium-activated channel subfamily M alpha 1
chr10_-_77637721 0.45 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
potassium calcium-activated channel subfamily M alpha 1
chr14_+_39233884 0.45 ENST00000553728.1
MIA SH3 domain ER export factor 2
chr4_-_89837106 0.45 ENST00000394986.5
ENST00000394991.8
ENST00000506244.5
ENST00000394989.6
ENST00000673902.1
ENST00000674129.1
synuclein alpha
chr19_+_35106510 0.45 ENST00000648240.1
novel protein
chr14_+_21918161 0.45 ENST00000390439.2
T cell receptor alpha variable 13-2
chrX_-_70289888 0.45 ENST00000239666.9
ENST00000374454.1
PDZ domain containing 11
chr22_+_24806265 0.44 ENST00000400359.4
small G protein signaling modulator 1
chrX_+_115561162 0.44 ENST00000355899.8
ENST00000626746.2
ENST00000289290.7
plastin 3
chr21_-_44711555 0.44 ENST00000323084.9
thrombospondin type laminin G domain and EAR repeats
chr12_-_52796110 0.43 ENST00000417996.2
keratin 3
chr10_-_15371225 0.43 ENST00000378116.9
family with sequence similarity 171 member A1
chr18_+_45615473 0.43 ENST00000255226.11
solute carrier family 14 member 2
chr7_-_29146527 0.42 ENST00000265394.10
carboxypeptidase vitellogenic like
chrX_-_1537165 0.42 ENST00000381297.10
P2Y receptor family member 8
chr22_+_24806169 0.42 ENST00000610372.4
ENST00000400358.9
small G protein signaling modulator 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 13.8 GO:0006982 response to lipid hydroperoxide(GO:0006982)
1.4 4.1 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
1.0 3.0 GO:0072034 primary prostatic bud elongation(GO:0060516) renal vesicle induction(GO:0072034)
0.9 5.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.8 2.5 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.7 9.9 GO:0031642 negative regulation of myelination(GO:0031642)
0.5 0.5 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.5 3.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.5 6.1 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.4 2.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.4 1.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.4 1.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.3 2.0 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.3 1.7 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 1.4 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 3.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.3 2.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.3 2.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.3 2.0 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.2 1.0 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.2 1.2 GO:0045337 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.2 2.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 1.9 GO:0051013 microtubule severing(GO:0051013)
0.2 3.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 1.6 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 1.5 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.2 0.6 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.2 0.5 GO:0043006 reduction of food intake in response to dietary excess(GO:0002023) activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2 0.6 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.6 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.5 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 1.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 3.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.4 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.3 GO:0036245 cellular response to menadione(GO:0036245)
0.1 0.3 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 1.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.8 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052) pentose catabolic process(GO:0019323)
0.1 0.3 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.1 2.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.4 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.5 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 1.0 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.2 GO:1900168 glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.1 0.6 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.8 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.3 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 1.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 2.3 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717)
0.1 3.1 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.6 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.5 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.6 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 0.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 1.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.4 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.8 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.9 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.7 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.3 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 1.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 0.3 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 1.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.3 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 2.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 3.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.4 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.2 GO:0071626 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.1 0.2 GO:1904640 response to methionine(GO:1904640)
0.1 0.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 1.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.3 GO:0016240 autophagosome docking(GO:0016240)
0.1 2.6 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.1 0.3 GO:0070836 caveola assembly(GO:0070836)
0.1 1.0 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 0.4 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 0.5 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.6 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.8 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 2.4 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 1.5 GO:0001556 oocyte maturation(GO:0001556)
0.0 1.7 GO:0000732 strand displacement(GO:0000732)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 1.7 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.5 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.0 0.3 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.3 GO:0000189 MAPK import into nucleus(GO:0000189) regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.0 0.9 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 1.4 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.5 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 1.0 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.4 GO:0008209 androgen metabolic process(GO:0008209)
0.0 0.5 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 3.7 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.8 GO:0044804 nucleophagy(GO:0044804)
0.0 0.6 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.3 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 1.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.9 GO:0061377 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0 0.3 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0007512 adult heart development(GO:0007512)
0.0 0.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.6 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.5 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.8 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.4 GO:0030239 myofibril assembly(GO:0030239)
0.0 5.4 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.3 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:2000828 parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.2 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 2.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 1.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.9 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.2 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.5 GO:0007271 synaptic transmission, cholinergic(GO:0007271)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.6 6.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 1.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 1.6 GO:0002177 manchette(GO:0002177)
0.2 1.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 2.2 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 2.2 GO:0070852 cell body fiber(GO:0070852)
0.2 0.8 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 0.6 GO:0000811 GINS complex(GO:0000811)
0.2 1.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.8 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 1.4 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 3.8 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.4 GO:0030478 actin cap(GO:0030478)
0.1 0.6 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 0.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 5.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 2.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 2.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.8 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.3 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 1.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 2.1 GO:0016235 aggresome(GO:0016235)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.6 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 2.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0000791 euchromatin(GO:0000791)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0042588 zymogen granule(GO:0042588)
0.0 3.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 3.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.7 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 1.2 GO:0031672 A band(GO:0031672)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.2 GO:0005903 brush border(GO:0005903)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 3.8 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 2.5 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.8 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 13.8 GO:0008430 selenium binding(GO:0008430)
1.0 3.0 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.5 2.5 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.4 1.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3 2.0 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 2.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.3 1.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 3.6 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.3 3.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 0.8 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.3 1.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 1.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 2.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.6 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.2 5.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.9 GO:0004969 histamine receptor activity(GO:0004969)
0.2 1.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 3.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 1.4 GO:0051373 FATZ binding(GO:0051373)
0.2 1.0 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.2 4.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.2 0.5 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 6.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 0.8 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 2.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 0.6 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 2.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.5 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.9 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.7 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 3.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 2.2 GO:0070628 proteasome binding(GO:0070628)
0.1 10.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.7 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.4 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 1.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 1.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 1.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 3.7 GO:0070888 E-box binding(GO:0070888)
0.0 1.5 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 15.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 1.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0042731 PH domain binding(GO:0042731)
0.0 0.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 2.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 1.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 2.4 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0043199 sulfate binding(GO:0043199)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 7.5 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 16.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.5 PID ARF 3PATHWAY Arf1 pathway
0.0 3.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 2.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.6 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 3.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 3.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 3.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 8.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 4.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 3.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 2.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 2.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 2.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 2.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 1.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 8.1 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation