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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NKX2-6

Z-value: 0.78

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Transcription factors associated with NKX2-6

Gene Symbol Gene ID Gene Info
ENSG00000180053.8 NKX2-6

Activity profile of NKX2-6 motif

Sorted Z-values of NKX2-6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_-_56465130 4.73 ENST00000260453.4
meiosis specific nuclear structural 1
chr6_+_32439866 4.58 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr6_-_131951364 4.49 ENST00000367976.4
cellular communication network factor 2
chr11_-_119196769 3.01 ENST00000415318.2
coiled-coil domain containing 153
chr3_-_121660892 2.32 ENST00000428394.6
ENST00000314583.8
hematopoietic cell-specific Lyn substrate 1
chr5_-_43412323 2.29 ENST00000361115.4
C-C motif chemokine ligand 28
chr8_-_132625378 2.24 ENST00000522789.5
leucine rich repeat containing 6
chr8_+_98064522 2.22 ENST00000545282.1
glutamate rich 5
chr11_+_27041313 2.13 ENST00000528583.5
gamma-butyrobetaine hydroxylase 1
chr11_+_27040725 2.12 ENST00000529202.5
ENST00000263182.8
gamma-butyrobetaine hydroxylase 1
chr3_-_120647018 1.84 ENST00000475447.2
homogentisate 1,2-dioxygenase
chr11_+_63369779 1.81 ENST00000279178.4
solute carrier family 22 member 9
chr9_+_72114595 1.80 ENST00000545168.5
guanine deaminase
chr16_+_78022538 1.78 ENST00000651443.1
ENST00000299642.10
C-type lectin domain family 3 member A
chr7_+_121873089 1.73 ENST00000651065.1
protein tyrosine phosphatase receptor type Z1
chr7_+_23680130 1.67 ENST00000409192.7
ENST00000409653.5
ENST00000409994.3
ENST00000344962.9
family with sequence similarity 221 member A
chr1_+_20186076 1.64 ENST00000375099.4
UBX domain protein 10
chr12_-_89526253 1.64 ENST00000547474.1
POC1B-GALNT4 readthrough
chr3_+_186996444 1.58 ENST00000676633.1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr5_+_140848360 1.58 ENST00000532602.2
protocadherin alpha 9
chr7_-_138627444 1.53 ENST00000463557.1
SVOP like
chr7_+_121873152 1.45 ENST00000650826.1
ENST00000650728.1
ENST00000393386.7
ENST00000651390.1
ENST00000651842.1
ENST00000650681.1
protein tyrosine phosphatase receptor type Z1
chr12_-_89526164 1.43 ENST00000548729.5
POC1B-GALNT4 readthrough
chr6_+_108848387 1.26 ENST00000368972.7
ENST00000392644.9
armadillo repeat containing 2
chr16_-_23713197 1.24 ENST00000256797.9
ENST00000457008.6
endoplasmic reticulum to nucleus signaling 2
chr7_+_134127299 1.24 ENST00000645682.1
ENST00000285928.2
leucine rich repeats and guanylate kinase domain containing
chr11_-_111379268 1.18 ENST00000393067.8
POU class 2 homeobox associating factor 1
chr12_+_55681711 1.16 ENST00000394252.4
methyltransferase like 7B
chr10_-_5977492 1.15 ENST00000530685.5
ENST00000397255.7
ENST00000379971.5
ENST00000528354.5
ENST00000397250.6
ENST00000429135.2
interleukin 15 receptor subunit alpha
chr12_+_55681647 1.14 ENST00000614691.1
methyltransferase like 7B
chr4_-_185395882 1.13 ENST00000505916.6
LRP2 binding protein
chr4_-_155953851 1.03 ENST00000679136.1
ENST00000433477.4
ENST00000679996.1
ENST00000680741.1
ENST00000680553.1
ENST00000679942.1
cathepsin O
chr11_+_1870252 0.96 ENST00000612798.4
lymphocyte specific protein 1
chr3_+_171843337 0.96 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr3_-_115071333 0.96 ENST00000462705.5
zinc finger and BTB domain containing 20
chr6_-_79537423 0.95 ENST00000369846.9
ENST00000392959.5
ENST00000467898.3
lebercilin LCA5
chr12_-_49900250 0.93 ENST00000552669.5
Fas apoptotic inhibitory molecule 2
chr7_+_117020191 0.91 ENST00000434836.5
ENST00000393443.5
ENST00000465133.5
ENST00000477742.5
ENST00000393444.7
ENST00000393447.8
suppression of tumorigenicity 7
chr4_+_17577487 0.91 ENST00000606142.5
leucine aminopeptidase 3
chr22_+_30764252 0.91 ENST00000445781.5
ENST00000401475.5
oxysterol binding protein 2
chrX_-_53281524 0.90 ENST00000498281.2
IQ motif and Sec7 domain ArfGEF 2
chr1_+_156369202 0.83 ENST00000537040.6
Rh family B glycoprotein
chr15_-_45378519 0.81 ENST00000558163.1
ENST00000396659.8
ENST00000675323.1
ENST00000558336.5
glycine amidinotransferase
chr12_-_85836372 0.77 ENST00000361228.5
Ras association domain family member 9
chr17_+_60677822 0.77 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3 microtubule associated cell migration factor
chr1_-_169367746 0.75 ENST00000367811.8
ENST00000472647.5
NME/NM23 family member 7
chrX_-_53281566 0.74 ENST00000638583.1
ENST00000639161.2
ENST00000485377.5
IQ motif and Sec7 domain ArfGEF 2
chr12_-_14950606 0.72 ENST00000536592.5
Rho GDP dissociation inhibitor beta
chr1_-_160282458 0.71 ENST00000485079.1
novel protein
chr11_-_106022209 0.69 ENST00000301919.9
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT DNA binding domain containing 4 with coiled-coils
chrX_+_24693879 0.68 ENST00000379068.8
ENST00000677890.1
ENST00000379059.7
DNA polymerase alpha 1, catalytic subunit
chr20_-_290364 0.68 ENST00000382369.9
chromosome 20 open reading frame 96
chr11_+_99020940 0.66 ENST00000524871.6
contactin 5
chr3_-_41961989 0.66 ENST00000420927.5
ENST00000301831.9
ENST00000414606.1
unc-51 like kinase 4
chr1_+_171248471 0.64 ENST00000402921.6
ENST00000617670.6
ENST00000367750.7
flavin containing dimethylaniline monoxygenase 1
chr3_+_132597260 0.63 ENST00000249887.3
atypical chemokine receptor 4
chr20_-_290717 0.63 ENST00000360321.7
ENST00000400269.4
chromosome 20 open reading frame 96
chr11_-_62754141 0.62 ENST00000527994.1
ENST00000394807.5
ENST00000673933.1
zinc finger and BTB domain containing 3
chr17_-_58529277 0.62 ENST00000579371.5
septin 4
chr19_+_10452891 0.61 ENST00000344979.7
phosphodiesterase 4A
chr1_-_160031946 0.60 ENST00000368090.5
phosphatidylinositol glycan anchor biosynthesis class M
chr17_-_58529303 0.60 ENST00000580844.5
septin 4
chr17_-_49646581 0.59 ENST00000510476.5
ENST00000503676.5
speckle type BTB/POZ protein
chr1_-_107688492 0.59 ENST00000415432.6
vav guanine nucleotide exchange factor 3
chr15_+_65550819 0.59 ENST00000569894.5
3-hydroxyacyl-CoA dehydratase 3
chr1_+_158289916 0.58 ENST00000368170.8
CD1c molecule
chrX_+_10156960 0.58 ENST00000380833.9
chloride voltage-gated channel 4
chr17_-_58529344 0.57 ENST00000317268.7
septin 4
chr22_-_38084093 0.54 ENST00000681075.1
solute carrier family 16 member 8
chr19_+_51573171 0.54 ENST00000436511.2
zinc finger protein 175
chrX_+_51406947 0.54 ENST00000342995.4
EZH inhibitory protein
chr7_+_75915148 0.53 ENST00000461988.6
ENST00000421059.1
ENST00000394893.5
ENST00000412521.5
ENST00000414186.5
cytochrome p450 oxidoreductase
chr10_-_27240505 0.53 ENST00000375888.5
ENST00000676732.1
acyl-CoA binding domain containing 5
chr9_-_83063159 0.53 ENST00000340717.4
RAS and EF-hand domain containing
chr19_-_6459735 0.51 ENST00000334510.9
ENST00000301454.9
solute carrier family 25 member 23
chr12_-_89526011 0.50 ENST00000313546.8
POC1 centriolar protein B
chr20_-_33674359 0.49 ENST00000606690.5
ENST00000439478.5
ENST00000246190.11
ENST00000375238.8
N-terminal EF-hand calcium binding protein 3
chr3_-_15065240 0.49 ENST00000449354.6
ENST00000253686.7
ENST00000444840.6
mitochondrial ribosomal protein S25
chr12_-_109093458 0.48 ENST00000536242.1
ENST00000343075.7
ENST00000429722.3
ENST00000536358.1
ENST00000619381.4
alkB homolog 2, alpha-ketoglutarate dependent dioxygenase
chr3_+_32685128 0.47 ENST00000331889.10
ENST00000328834.9
CCR4-NOT transcription complex subunit 10
chr1_-_200669708 0.45 ENST00000436897.1
ENST00000447706.6
ENST00000331314.11
DEAD-box helicase 59
chr15_-_28099293 0.43 ENST00000431101.1
ENST00000445578.5
ENST00000353809.9
ENST00000354638.8
OCA2 melanosomal transmembrane protein
chr11_+_93330712 0.42 ENST00000298050.9
deuterosome assembly protein 1
chr8_-_94208548 0.42 ENST00000027335.8
ENST00000441892.6
ENST00000521491.1
cadherin 17
chr12_+_119593758 0.40 ENST00000426426.3
transmembrane protein 233
chr20_+_19886506 0.39 ENST00000648440.1
Ras and Rab interactor 2
chr13_+_111114550 0.39 ENST00000317133.9
Rho guanine nucleotide exchange factor 7
chr17_-_64497025 0.38 ENST00000539111.7
DNA polymerase gamma 2, accessory subunit
chr2_+_112911159 0.38 ENST00000263326.8
interleukin 37
chrX_-_133097095 0.37 ENST00000511190.5
ubiquitin specific peptidase 26
chr4_-_170003738 0.37 ENST00000502832.1
ENST00000393704.3
microfibril associated protein 3 like
chr7_-_151080787 0.37 ENST00000540185.5
ENST00000297532.11
Fas activated serine/threonine kinase
chr11_-_111512339 0.37 ENST00000525791.5
ENST00000456861.2
ENST00000356018.6
BTG anti-proliferation factor 4
chr2_+_108719473 0.36 ENST00000283195.11
RAN binding protein 2
chr8_+_42541569 0.35 ENST00000417410.7
ENST00000518574.1
ENST00000414154.6
small integral membrane protein 19
chr1_+_205256189 0.34 ENST00000329800.7
transmembrane and coiled-coil domain family 2
chr7_-_91880672 0.34 ENST00000456229.1
ENST00000442961.1
ENST00000406735.6
ENST00000419292.1
ENST00000351870.8
mitochondrial transcription termination factor 1
chr9_-_33402449 0.34 ENST00000377425.8
aquaporin 7
chr3_-_39192584 0.33 ENST00000340369.4
ENST00000421646.1
ENST00000396251.1
xin actin binding repeat containing 1
chr5_-_111756245 0.33 ENST00000447165.6
neuronal regeneration related protein
chr3_+_36993798 0.31 ENST00000455445.6
ENST00000539477.6
ENST00000435176.5
ENST00000429117.5
ENST00000441265.6
mutL homolog 1
chr1_+_203127678 0.31 ENST00000640524.1
ENST00000337894.9
adenosine A1 receptor
chr11_-_119030848 0.30 ENST00000330775.9
ENST00000357590.9
ENST00000538950.5
ENST00000545985.5
solute carrier family 37 member 4
chr18_+_41955186 0.30 ENST00000639914.1
ENST00000262039.9
ENST00000398870.7
ENST00000586545.5
ENST00000585528.5
phosphatidylinositol 3-kinase catalytic subunit type 3
chr17_+_62423891 0.30 ENST00000616852.1
ENST00000311506.10
methyltransferase like 2A
chr12_-_55842927 0.29 ENST00000322569.9
ENST00000409200.7
matrix metallopeptidase 19
chr12_-_49897056 0.29 ENST00000552863.5
Fas apoptotic inhibitory molecule 2
chr7_+_128476748 0.29 ENST00000262432.13
ENST00000480046.5
methyltransferase like 2B
chr8_+_42541775 0.29 ENST00000416469.6
small integral membrane protein 19
chr11_-_6619353 0.28 ENST00000642892.1
ENST00000645620.1
ENST00000533371.6
ENST00000647152.1
ENST00000644810.1
ENST00000299427.12
ENST00000682424.1
ENST00000644218.1
ENST00000528657.2
ENST00000531754.2
tripeptidyl peptidase 1
chr6_+_29396555 0.28 ENST00000623183.1
olfactory receptor family 12 subfamily D member 2
chr13_-_48095096 0.28 ENST00000258648.7
ENST00000378586.5
mediator complex subunit 4
chr10_-_5977535 0.28 ENST00000379977.8
interleukin 15 receptor subunit alpha
chr10_+_119892692 0.27 ENST00000369075.8
SEC23 interacting protein
chr3_+_36993350 0.27 ENST00000536378.5
ENST00000673899.1
ENST00000231790.8
ENST00000673715.1
ENST00000456676.6
ENST00000673673.1
mutL homolog 1
chr13_+_114235066 0.27 ENST00000252458.6
cell division cycle 16
chr9_+_131190119 0.27 ENST00000483497.6
nucleoporin 214
chr18_+_58362467 0.27 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chr8_-_100559702 0.26 ENST00000520311.5
ENST00000520552.5
ENST00000521345.1
ENST00000523000.5
ENST00000335659.7
ENST00000358990.3
ENST00000519597.5
ankyrin repeat domain 46
chr14_+_64214136 0.26 ENST00000557084.1
ENST00000458046.6
spectrin repeat containing nuclear envelope protein 2
chr12_-_70788914 0.25 ENST00000342084.8
protein tyrosine phosphatase receptor type R
chr10_-_5977589 0.25 ENST00000620345.4
ENST00000397251.7
ENST00000397248.6
ENST00000622442.4
ENST00000620865.4
interleukin 15 receptor subunit alpha
chr3_+_36993764 0.25 ENST00000674019.1
ENST00000458205.6
mutL homolog 1
chr12_-_262828 0.24 ENST00000343164.9
ENST00000436453.1
ENST00000445055.6
ENST00000546319.5
solute carrier family 6 member 13
chr4_-_78939352 0.24 ENST00000512733.5
progestin and adipoQ receptor family member 3
chr17_+_36534980 0.24 ENST00000614443.2
ENST00000619326.1
phosphatidylinositol glycan anchor biosynthesis class W
chr17_-_36534927 0.24 ENST00000610930.4
myosin XIX
chr4_-_137532452 0.23 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr9_-_83063135 0.22 ENST00000376447.4
RAS and EF-hand domain containing
chr5_+_141208697 0.21 ENST00000624949.1
ENST00000622978.1
ENST00000239450.4
protocadherin beta 12
chr7_-_30682473 0.20 ENST00000506074.6
corticotropin releasing hormone receptor 2
chr13_+_114235044 0.20 ENST00000252457.9
ENST00000375308.5
cell division cycle 16
chr9_-_33402551 0.20 ENST00000297988.6
ENST00000624075.3
ENST00000625032.1
ENST00000625109.3
aquaporin 7
chr11_-_61920267 0.19 ENST00000531922.2
ENST00000301773.9
RAB3A interacting protein like 1
chr2_-_100104530 0.19 ENST00000432037.5
ENST00000673232.1
ENST00000423966.6
ENST00000409236.6
AF4/FMR2 family member 3
chr15_+_81182579 0.19 ENST00000302987.9
interleukin 16
chr8_-_42541898 0.19 ENST00000342228.7
solute carrier family 20 member 2
chr6_-_159045010 0.18 ENST00000338313.5
T cell activation RhoGTPase activating protein
chr19_-_49036885 0.18 ENST00000604577.1
ENST00000591656.1
ENST00000301407.8
ENST00000601167.1
novel protein
chorionic gonadotropin subunit beta 1
chr5_+_156850292 0.18 ENST00000522232.3
PPP1R2 family member B
chr15_+_75347030 0.18 ENST00000566313.5
ENST00000355059.9
ENST00000568059.1
ENST00000568881.1
nei like DNA glycosylase 1
chr19_+_7629771 0.17 ENST00000594797.6
ENST00000456958.7
ENST00000601406.5
PET100 cytochrome c oxidase chaperone
chr16_-_69339493 0.17 ENST00000562595.5
ENST00000615447.1
ENST00000306875.10
ENST00000562081.2
component of oligomeric golgi complex 8
chr19_+_496454 0.17 ENST00000346144.8
ENST00000215637.8
ENST00000382683.8
mucosal vascular addressin cell adhesion molecule 1
chr18_+_7754959 0.17 ENST00000400053.8
protein tyrosine phosphatase receptor type M
chr17_-_51260032 0.17 ENST00000586178.6
mbt domain containing 1
chr6_+_125781108 0.17 ENST00000368357.7
nuclear receptor coactivator 7
chr19_-_10565990 0.17 ENST00000539027.5
ENST00000312962.12
ENST00000543682.3
ENST00000652042.1
ENST00000432197.5
KRI1 homolog
chr7_+_123601836 0.16 ENST00000434204.5
ankyrin repeat and SOCS box containing 15
chr19_-_7629531 0.16 ENST00000358368.5
XPA binding protein 2
chr17_-_74531467 0.16 ENST00000314401.3
ENST00000392621.6
CD300 molecule like family member b
chr16_-_1230089 0.15 ENST00000612142.1
ENST00000606293.5
tryptase beta 2
chr19_-_55599493 0.15 ENST00000221665.5
ENST00000592585.1
FLT3 interacting zinc finger 1
chr1_-_203175783 0.15 ENST00000621380.1
ENST00000255416.9
myosin binding protein H
chr7_+_123601815 0.15 ENST00000451215.6
ankyrin repeat and SOCS box containing 15
chr17_-_36534841 0.14 ENST00000614623.5
ENST00000621344.4
myosin XIX
chr11_-_76669985 0.14 ENST00000407242.6
ENST00000421973.1
leucine rich repeat containing 32
chr17_+_42998264 0.14 ENST00000589037.5
ribosomal protein L27
chr7_+_142791635 0.14 ENST00000633705.1
T cell receptor beta constant 1
chr5_-_177783398 0.14 ENST00000510276.5
family with sequence similarity 153 member A
chr17_+_42998379 0.14 ENST00000253788.12
ENST00000589913.6
ribosomal protein L27
chr1_-_36397880 0.13 ENST00000315732.3
LSM10, U7 small nuclear RNA associated
chr12_-_56645955 0.12 ENST00000552959.5
ENST00000551020.5
ENST00000553007.2
ENST00000262030.8
ATP synthase F1 subunit beta
chr7_+_75882044 0.12 ENST00000428119.1
rhomboid domain containing 2
chr2_+_1413456 0.12 ENST00000539820.5
ENST00000382269.7
ENST00000345913.8
ENST00000329066.9
ENST00000382201.7
thyroid peroxidase
chr17_+_51260520 0.12 ENST00000225298.12
UTP18 small subunit processome component
chr2_-_68952880 0.11 ENST00000481498.1
ENST00000328895.9
gastrokine 2
chr17_-_36534883 0.11 ENST00000620640.4
myosin XIX
chr4_+_112818032 0.11 ENST00000672356.1
ENST00000672955.1
ankyrin 2
chr5_-_134174765 0.11 ENST00000520417.1
S-phase kinase associated protein 1
chr22_-_43143339 0.11 ENST00000327555.5
ENST00000290429.11
malonyl-CoA-acyl carrier protein transacylase
chr4_+_112818088 0.11 ENST00000673044.1
ENST00000672696.1
ENST00000672315.1
ENST00000672088.1
ENST00000671793.1
ENST00000672402.1
ENST00000671825.1
ENST00000672312.1
ENST00000672830.1
ENST00000672731.1
ENST00000671854.1
ENST00000672350.1
ENST00000672684.1
ENST00000672934.1
ENST00000673546.1
ENST00000673573.1
ENST00000503423.6
ENST00000673255.1
ENST00000671893.1
ENST00000672246.1
ENST00000672930.1
ENST00000673334.1
ENST00000673453.1
ENST00000673555.1
ENST00000672880.1
ENST00000672990.1
ENST00000673430.1
ENST00000673298.1
ENST00000672068.1
ENST00000672362.1
ENST00000672793.1
ENST00000672209.1
ENST00000671756.1
ENST00000671809.1
ENST00000671906.1
ENST00000672090.1
ENST00000672177.1
ENST00000672759.1
ENST00000672965.1
ENST00000673109.1
ENST00000503271.5
ENST00000506722.5
ENST00000673536.1
ENST00000672986.1
ankyrin 2
chr8_-_119638780 0.11 ENST00000522826.5
ENST00000520066.5
ENST00000259486.10
ENST00000075322.11
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr1_+_19251786 0.10 ENST00000330263.5
MRT4 homolog, ribosome maturation factor
chr1_+_158999963 0.10 ENST00000566111.5
interferon gamma inducible protein 16
chr9_+_65700287 0.10 ENST00000489273.1
COBW domain containing 5
chr9_-_109119915 0.10 ENST00000374586.8
transmembrane protein 245
chr2_-_174598206 0.09 ENST00000392546.6
ENST00000436221.1
WAS/WASL interacting protein family member 1
chr1_-_70354673 0.09 ENST00000370944.9
ENST00000262346.6
ankyrin repeat domain 13C
chr15_-_40828699 0.09 ENST00000299174.10
ENST00000427255.2
protein phosphatase 1 regulatory inhibitor subunit 14D
chr4_+_165378998 0.09 ENST00000402744.9
carboxypeptidase E
chr14_+_31025634 0.09 ENST00000673317.1
ENST00000556232.6
ENST00000542754.7
ENST00000554345.6
ENST00000334725.8
ENST00000554609.6
ENST00000313566.11
adaptor related protein complex 4 subunit sigma 1
chr6_-_159044980 0.09 ENST00000367066.8
T cell activation RhoGTPase activating protein
chr10_-_5978022 0.08 ENST00000525219.6
interleukin 15 receptor subunit alpha
chr3_+_186717348 0.08 ENST00000447445.1
ENST00000287611.8
ENST00000644859.2
kininogen 1
chr19_-_50476725 0.07 ENST00000595790.5
family with sequence similarity 71 member E1
chr4_+_119027335 0.07 ENST00000627783.2
synaptopodin 2
chr11_+_119087979 0.07 ENST00000535253.5
ENST00000392841.1
ENST00000648374.1
hydroxymethylbilane synthase
chr2_+_202912214 0.06 ENST00000402905.7
ENST00000320443.12
ENST00000414490.5
ENST00000431787.5
ENST00000444724.5
ENST00000414857.5
ENST00000438828.4
ENST00000430899.5
ENST00000445120.5
ENST00000441569.5
ENST00000432024.5
ENST00000443740.5
ENST00000414439.5
ENST00000428585.5
ENST00000447539.5
ENST00000434998.5
calcium responsive transcription factor
chr8_-_70071226 0.06 ENST00000276594.3
PR/SET domain 14
chr1_+_21468442 0.06 ENST00000619554.1
NBPF member 3
chr22_+_41621977 0.06 ENST00000405506.2
X-ray repair cross complementing 6
chr12_+_123762188 0.06 ENST00000409039.8
ENST00000673944.1
dynein axonemal heavy chain 10
chr1_-_21050952 0.05 ENST00000264211.12
eukaryotic translation initiation factor 4 gamma 3
chr12_-_43758748 0.05 ENST00000416848.6
ENST00000550784.5
ENST00000547156.1
ENST00000549868.1
ENST00000551923.5
ENST00000344862.10
ENST00000431332.7
pseudouridine synthase 7 like
chr7_+_100602344 0.05 ENST00000223061.6
procollagen C-endopeptidase enhancer
chr9_-_131531224 0.05 ENST00000372208.7
ENST00000372215.5
uridine-cytidine kinase 1
chr6_-_159045104 0.04 ENST00000326965.7
T cell activation RhoGTPase activating protein
chr17_+_42998779 0.04 ENST00000586277.5
ribosomal protein L27
chr11_+_99021066 0.04 ENST00000527185.5
ENST00000528682.5
contactin 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.6 1.8 GO:0006147 guanine catabolic process(GO:0006147)
0.4 4.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 2.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 0.8 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 4.7 GO:0070986 left/right axis specification(GO:0070986)
0.2 0.8 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.2 1.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 3.2 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.2 0.5 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.2 0.7 GO:0006272 leading strand elongation(GO:0006272)
0.2 0.5 GO:0097274 urea homeostasis(GO:0097274)
0.2 1.8 GO:0015747 urate transport(GO:0015747)
0.1 2.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 2.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.3 GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.1 0.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 1.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.7 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.3 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.1 0.4 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 0.4 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.6 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.8 GO:0030242 pexophagy(GO:0030242)
0.1 1.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.6 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.6 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.5 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 1.0 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.5 GO:0015793 glycerol transport(GO:0015793)
0.1 0.5 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.8 GO:0006600 creatine metabolic process(GO:0006600)
0.0 1.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.3 GO:0001554 luteolysis(GO:0001554)
0.0 0.5 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.7 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827) germ-line stem cell population maintenance(GO:0030718)
0.0 1.2 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.6 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.6 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.1 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 1.0 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0072534 perineuronal net(GO:0072534)
0.2 1.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 4.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.8 GO:0005715 late recombination nodule(GO:0005715)
0.2 1.2 GO:0002177 manchette(GO:0002177)
0.1 0.4 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 0.4 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 1.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.9 GO:0097440 apical dendrite(GO:0097440)
0.0 4.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 0.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 1.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 1.8 GO:0008892 guanine deaminase activity(GO:0008892)
0.3 4.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 1.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 0.8 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 0.5 GO:0035514 DNA demethylase activity(GO:0035514)
0.2 1.8 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.4 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 3.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.5 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.6 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.6 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.8 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 0.5 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 0.3 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.3 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.2 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 1.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 2.3 GO:0008009 chemokine activity(GO:0008009)
0.0 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0016419 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
0.0 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 2.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 4.0 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 2.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 2.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 7.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.5 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors