ISMARA results: NKX2-8

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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NKX2-8

Z-value: 0.55

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Transcription factors associated with NKX2-8

Gene Symbol	Gene ID	Gene Info
NKX2-8 Ensembl NCBI GeneCards UniProt	ENSG00000136327.7	NKX2-8

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NKX2-8	hg38_v1_chr14_-_36582593_36582626	0.15	4.4e-01	Click!

Activity profile of NKX2-8 motif

Sorted Z-values of NKX2-8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-8

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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr19_-_50833187 Show fit	0.94	ENST00000598673.1	KLK15 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 15
chr17_+_78214286 Show fit	0.92	ENST00000592734.5 ENST00000587746.5	BIRC5 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 5
chr15_-_56465130 Show fit	0.71	ENST00000260453.4	MNS1 Ensembl NCBI GeneCards UniProt Show fit	meiosis specific nuclear structural 1
chr19_-_50909328 Show fit	0.68	ENST00000431178.2	KLK4 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 4
chr17_+_78214186 Show fit	0.68	ENST00000301633.8 ENST00000350051.8 ENST00000374948.6 ENST00000590449.1	BIRC5 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 5
chr15_+_40161003 Show fit	0.65	ENST00000412359.7 ENST00000287598.11	BUB1B Ensembl NCBI GeneCards UniProt Show fit	BUB1 mitotic checkpoint serine/threonine kinase B
chr19_+_43533384 Show fit	0.51	ENST00000601282.1	ZNF575 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 575
chr6_+_69232406 Show fit	0.49	ENST00000238918.12	ADGRB3 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor B3
chr11_+_72080595 Show fit	0.46	ENST00000647530.1 ENST00000539271.6 ENST00000642510.1	LRTOMT Ensembl NCBI GeneCards UniProt Show fit	leucine rich transmembrane and O-methyltransferase domain containing
chr11_+_72080803 Show fit	0.45	ENST00000423494.6 ENST00000539587.6 ENST00000536917.2 ENST00000538478.5 ENST00000324866.11 ENST00000643715.1 ENST00000439209.5	LRTOMT Ensembl NCBI GeneCards UniProt Show fit ENSG00000284922.2 Ensembl NCBI GeneCards UniProt Show fit	leucine rich transmembrane and O-methyltransferase domain containing leucine rich transmembrane and O-methyltransferase domain containing
chrX_+_41688967 Show fit	0.44	ENST00000378142.9	GPR34 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 34
chr3_-_180679468 Show fit	0.43	ENST00000651046.1 ENST00000476379.6	CCDC39 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 39
chr6_-_131951364 Show fit	0.42	ENST00000367976.4	CCN2 Ensembl NCBI GeneCards UniProt Show fit	cellular communication network factor 2
chr6_+_29439939 Show fit	0.42	ENST00000622521.1	OR10C1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 10 subfamily C member 1
chrX_+_41689006 Show fit	0.42	ENST00000378138.5 ENST00000620846.1 ENST00000649219.1	GPR34 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 34
chr10_-_73641450 Show fit	0.41	ENST00000359322.5	MYOZ1 Ensembl NCBI GeneCards UniProt Show fit	myozenin 1
chr2_-_158456702 Show fit	0.40	ENST00000409889.1 ENST00000283233.10	CCDC148 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 148
chr12_-_24562438 Show fit	0.39	ENST00000646273.1 ENST00000659413.1 ENST00000446891.7	SOX5 Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 5
chr11_-_107719657 Show fit	0.37	ENST00000525934.1 ENST00000531293.1	SLN Ensembl NCBI GeneCards UniProt Show fit	sarcolipin
chr14_-_106875069 Show fit	0.37	ENST00000390639.2	IGHV7-81 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 7-81 (non-functional)
chr12_-_12684490 Show fit	0.36	ENST00000540510.1	GPR19 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 19
chr6_+_41042557 Show fit	0.35	ENST00000373158.6 ENST00000470917.1	TSPO2 Ensembl NCBI GeneCards UniProt Show fit	translocator protein 2
chr16_+_176659 Show fit	0.35	ENST00000320868.9 ENST00000397797.1	HBA1 Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit alpha 1
chr1_+_152985231 Show fit	0.35	ENST00000368762.1	SPRR1A Ensembl NCBI GeneCards UniProt Show fit	small proline rich protein 1A
chr11_+_5389377 Show fit	0.35	ENST00000328611.5	OR51M1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 51 subfamily M member 1
chr4_+_75556048 Show fit	0.35	ENST00000616557.1 ENST00000435974.2 ENST00000311623.9	ODAPH Ensembl NCBI GeneCards UniProt Show fit	odontogenesis associated phosphoprotein
chr22_+_19131271 Show fit	0.34	ENST00000399635.4	TSSK2 Ensembl NCBI GeneCards UniProt Show fit	testis specific serine kinase 2
chr10_-_77637789 Show fit	0.34	ENST00000481070.1 ENST00000640969.1 ENST00000286628.14 ENST00000638991.1 ENST00000639913.1 ENST00000480683.2	KCNMA1 Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily M alpha 1
chr14_-_106470788 Show fit	0.33	ENST00000434710.1	IGHV3-43 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-43
chr7_-_93226449 Show fit	0.33	ENST00000394468.7 ENST00000453812.2	HEPACAM2 Ensembl NCBI GeneCards UniProt Show fit	HEPACAM family member 2
chr4_-_99563984 Show fit	0.32	ENST00000394877.7	TRMT10A Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase 10A
chr4_-_99564026 Show fit	0.32	ENST00000394876.7	TRMT10A Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase 10A
chr16_-_20669855 Show fit	0.30	ENST00000524149.5	ACSM1 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase medium chain family member 1
chr17_+_7688427 Show fit	0.29	ENST00000396463.7 ENST00000534050.5	WRAP53 Ensembl NCBI GeneCards UniProt Show fit	WD repeat containing antisense to TP53
chr7_-_93219545 Show fit	0.28	ENST00000440868.5	HEPACAM2 Ensembl NCBI GeneCards UniProt Show fit	HEPACAM family member 2
chr7_-_93219564 Show fit	0.28	ENST00000341723.8	HEPACAM2 Ensembl NCBI GeneCards UniProt Show fit	HEPACAM family member 2
chr2_+_232633551 Show fit	0.28	ENST00000264059.8	EFHD1 Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain family member D1
chr20_+_33031648 Show fit	0.28	ENST00000349552.1	BPIFB6 Ensembl NCBI GeneCards UniProt Show fit	BPI fold containing family B member 6
chr14_-_91946989 Show fit	0.28	ENST00000556154.5	FBLN5 Ensembl NCBI GeneCards UniProt Show fit	fibulin 5
chr14_-_23155302 Show fit	0.27	ENST00000529705.6	SLC7A8 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 8
chr4_-_152679984 Show fit	0.27	ENST00000304385.8 ENST00000504064.1	TMEM154 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 154
chr4_-_99563668 Show fit	0.26	ENST00000273962.7	TRMT10A Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase 10A
chr1_+_172420681 Show fit	0.26	ENST00000367727.9	C1orf105 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 105
chr3_-_52454032 Show fit	0.26	ENST00000232975.8	TNNC1 Ensembl NCBI GeneCards UniProt Show fit	troponin C1, slow skeletal and cardiac type
chr17_-_9905248 Show fit	0.25	ENST00000226193.6	RCVRN Ensembl NCBI GeneCards UniProt Show fit	recoverin
chr16_+_58392462 Show fit	0.25	ENST00000318129.6	GINS3 Ensembl NCBI GeneCards UniProt Show fit	GINS complex subunit 3
chr5_-_176629943 Show fit	0.25	ENST00000510387.5 ENST00000506696.1	SNCB Ensembl NCBI GeneCards UniProt Show fit	synuclein beta
chr4_+_177309866 Show fit	0.24	ENST00000264596.4	NEIL3 Ensembl NCBI GeneCards UniProt Show fit	nei like DNA glycosylase 3
chr14_-_55027045 Show fit	0.24	ENST00000455555.1 ENST00000360586.8 ENST00000420358.2	WDHD1 Ensembl NCBI GeneCards UniProt Show fit	WD repeat and HMG-box DNA binding protein 1
chr14_-_106235582 Show fit	0.23	ENST00000390607.2	IGHV3-21 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-21
chr18_+_31591869 Show fit	0.23	ENST00000237014.8	TTR Ensembl NCBI GeneCards UniProt Show fit	transthyretin
chr12_+_13196718 Show fit	0.23	ENST00000431267.2 ENST00000542474.5 ENST00000544053.5 ENST00000256951.10	EMP1 Ensembl NCBI GeneCards UniProt Show fit	epithelial membrane protein 1
chr3_-_149086488 Show fit	0.23	ENST00000392912.6 ENST00000465259.5 ENST00000310053.10 ENST00000494055.5	HLTF Ensembl NCBI GeneCards UniProt Show fit	helicase like transcription factor
chr12_+_25052512 Show fit	0.23	ENST00000557489.5 ENST00000354454.7 ENST00000536173.5	IRAG2 Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr2_-_135531172 Show fit	0.23	ENST00000264159.11	ZRANB3 Ensembl NCBI GeneCards UniProt Show fit	zinc finger RANBP2-type containing 3
chr1_+_16022030 Show fit	0.22	ENST00000331433.5	CLCNKA Ensembl NCBI GeneCards UniProt Show fit	chloride voltage-gated channel Ka
chr2_-_151261839 Show fit	0.21	ENST00000331426.6	RBM43 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 43
chr17_-_8295342 Show fit	0.21	ENST00000579192.5 ENST00000577745.2	SLC25A35 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 35
chrX_-_149549924 Show fit	0.21	ENST00000431993.4	HSFX3 Ensembl NCBI GeneCards UniProt Show fit	heat shock transcription factor family, X-linked member 3
chr19_+_34365173 Show fit	0.20	ENST00000589640.5 ENST00000591204.5 ENST00000589399.6 ENST00000356487.11	GPI Ensembl NCBI GeneCards UniProt Show fit	glucose-6-phosphate isomerase
chr14_-_106130061 Show fit	0.20	ENST00000390602.3	IGHV3-13 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-13
chr16_+_58392391 Show fit	0.20	ENST00000426538.6 ENST00000328514.11	GINS3 Ensembl NCBI GeneCards UniProt Show fit	GINS complex subunit 3
chr16_+_172869 Show fit	0.20	ENST00000251595.11 ENST00000397806.1 ENST00000484216.1	HBA2 Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit alpha 2
chr6_+_99606833 Show fit	0.20	ENST00000369215.5	PRDM13 Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 13
chr1_-_155033778 Show fit	0.19	ENST00000368424.4	DCST2 Ensembl NCBI GeneCards UniProt Show fit	DC-STAMP domain containing 2
chr12_+_49265071 Show fit	0.19	ENST00000549183.1 ENST00000639419.1 ENST00000301072.11	TUBA1C Ensembl NCBI GeneCards UniProt Show fit	tubulin alpha 1c
chr12_+_25052634 Show fit	0.19	ENST00000548766.5	IRAG2 Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr17_-_15260752 Show fit	0.19	ENST00000676329.1 ENST00000675551.1 ENST00000644020.1 ENST00000674947.1	PMP22 Ensembl NCBI GeneCards UniProt Show fit	peripheral myelin protein 22
chr10_-_77637721 Show fit	0.18	ENST00000638848.1 ENST00000639406.1 ENST00000618048.2 ENST00000639120.1 ENST00000640834.1 ENST00000639601.1 ENST00000638514.1 ENST00000457953.6 ENST00000639090.1 ENST00000639489.1 ENST00000372440.6 ENST00000404771.8 ENST00000638203.1 ENST00000638306.1 ENST00000638351.1 ENST00000638606.1 ENST00000639591.1 ENST00000640182.1 ENST00000640605.1 ENST00000640141.1	KCNMA1 Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily M alpha 1
chr2_+_109614328 Show fit	0.18	ENST00000356454.5	SOWAHC Ensembl NCBI GeneCards UniProt Show fit	sosondowah ankyrin repeat domain family member C
chr8_+_66493514 Show fit	0.18	ENST00000521495.5	VXN Ensembl NCBI GeneCards UniProt Show fit	vexin
chr2_+_135531460 Show fit	0.18	ENST00000683871.1 ENST00000409478.5 ENST00000264160.8 ENST00000438014.5	R3HDM1 Ensembl NCBI GeneCards UniProt Show fit	R3H domain containing 1
chr2_-_89010515 Show fit	0.17	ENST00000493819.1	IGKV1-9 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chr22_+_31122923 Show fit	0.17	ENST00000620191.4 ENST00000412277.6 ENST00000412985.5 ENST00000331075.10 ENST00000420017.5 ENST00000400294.6 ENST00000405300.5 ENST00000404390.7	INPP5J Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-5-phosphatase J
chr3_+_151086889 Show fit	0.17	ENST00000474524.5 ENST00000273432.8	MED12L Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 12L
chr14_-_24263162 Show fit	0.16	ENST00000206765.11 ENST00000544573.5	TGM1 Ensembl NCBI GeneCards UniProt Show fit	transglutaminase 1
chrX_-_64976435 Show fit	0.16	ENST00000374839.8	ZC4H2 Ensembl NCBI GeneCards UniProt Show fit	zinc finger C4H2-type containing
chr11_+_18132565 Show fit	0.15	ENST00000621697.2	MRGPRX3 Ensembl NCBI GeneCards UniProt Show fit	MAS related GPR family member X3
chrX_-_64976500 Show fit	0.15	ENST00000447788.6	ZC4H2 Ensembl NCBI GeneCards UniProt Show fit	zinc finger C4H2-type containing
chr6_-_32666648 Show fit	0.15	ENST00000399082.7 ENST00000399079.7 ENST00000374943.8 ENST00000434651.6	HLA-DQB1 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ beta 1
chr16_-_68015911 Show fit	0.15	ENST00000574912.1	DPEP2NB Ensembl NCBI GeneCards UniProt Show fit	DPEP2 neighbor
chr22_+_38468036 Show fit	0.15	ENST00000409006.3 ENST00000216014.9	KDELR3 Ensembl NCBI GeneCards UniProt Show fit	KDEL endoplasmic reticulum protein retention receptor 3
chr19_+_45340736 Show fit	0.15	ENST00000391946.7	KLC3 Ensembl NCBI GeneCards UniProt Show fit	kinesin light chain 3
chr2_-_206159410 Show fit	0.14	ENST00000457011.5 ENST00000440274.5 ENST00000432169.5 ENST00000233190.11	NDUFS1 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase core subunit S1
chr14_-_106088573 Show fit	0.14	ENST00000632099.1	IGHV3-64D Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-64D
chr1_+_173824626 Show fit	0.14	ENST00000648960.1 ENST00000648807.1 ENST00000649067.1 ENST00000649689.2	DARS2 Ensembl NCBI GeneCards UniProt Show fit	aspartyl-tRNA synthetase 2, mitochondrial
chr12_+_25052732 Show fit	0.14	ENST00000547044.5	IRAG2 Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr7_+_30771388 Show fit	0.13	ENST00000265299.6	MINDY4 Ensembl NCBI GeneCards UniProt Show fit	MINDY lysine 48 deubiquitinase 4
chr12_-_102197827 Show fit	0.13	ENST00000329406.5	PMCH Ensembl NCBI GeneCards UniProt Show fit	pro-melanin concentrating hormone
chr9_-_21217311 Show fit	0.13	ENST00000380216.1	IFNA16 Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 16
chr18_+_46917561 Show fit	0.13	ENST00000683218.1	KATNAL2 Ensembl NCBI GeneCards UniProt Show fit	katanin catalytic subunit A1 like 2
chr10_+_99732211 Show fit	0.13	ENST00000370476.10 ENST00000370472.4	CUTC Ensembl NCBI GeneCards UniProt Show fit	cutC copper transporter
chr17_-_3691887 Show fit	0.13	ENST00000552050.5	P2RX5 Ensembl NCBI GeneCards UniProt Show fit	purinergic receptor P2X 5
chr5_-_181261078 Show fit	0.13	ENST00000611618.1	TRIM52 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 52
chr12_-_75209814 Show fit	0.12	ENST00000549446.6	KCNC2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily C member 2
chr14_+_63761836 Show fit	0.12	ENST00000674003.1	SYNE2 Ensembl NCBI GeneCards UniProt Show fit	spectrin repeat containing nuclear envelope protein 2
chr1_-_23424618 Show fit	0.12	ENST00000476978.2	TCEA3 Ensembl NCBI GeneCards UniProt Show fit	transcription elongation factor A3
chr1_+_173824694 Show fit	0.12	ENST00000647645.1	DARS2 Ensembl NCBI GeneCards UniProt Show fit	aspartyl-tRNA synthetase 2, mitochondrial
chr22_-_19178402 Show fit	0.12	ENST00000451283.5	SLC25A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 1
chr19_+_39342396 Show fit	0.12	ENST00000602243.5 ENST00000598913.5 ENST00000314471.10	SAMD4B Ensembl NCBI GeneCards UniProt Show fit	sterile alpha motif domain containing 4B
chr11_-_72642450 Show fit	0.12	ENST00000444035.6 ENST00000544570.5	PDE2A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 2A
chr8_-_123396412 Show fit	0.12	ENST00000287394.10	ATAD2 Ensembl NCBI GeneCards UniProt Show fit	ATPase family AAA domain containing 2
chr1_+_16022004 Show fit	0.12	ENST00000439316.6	CLCNKA Ensembl NCBI GeneCards UniProt Show fit	chloride voltage-gated channel Ka
chr1_+_54998927 Show fit	0.12	ENST00000651561.1	BSND Ensembl NCBI GeneCards UniProt Show fit	barttin CLCNK type accessory subunit beta
chr11_-_19202004 Show fit	0.12	ENST00000648719.1	CSRP3 Ensembl NCBI GeneCards UniProt Show fit	cysteine and glycine rich protein 3
chr16_+_29663219 Show fit	0.11	ENST00000436527.5 ENST00000360121.4 ENST00000652691.1 ENST00000449759.2	SPN Ensembl NCBI GeneCards UniProt Show fit QPRT Ensembl NCBI GeneCards UniProt Show fit	sialophorin quinolinate phosphoribosyltransferase
chrX_+_153687918 Show fit	0.11	ENST00000253122.10	SLC6A8 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 8
chr17_+_64507029 Show fit	0.11	ENST00000553412.5	CEP95 Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 95
chr16_-_66918839 Show fit	0.11	ENST00000565235.2 ENST00000568632.5 ENST00000565796.5	CDH16 Ensembl NCBI GeneCards UniProt Show fit	cadherin 16
chr9_-_21187671 Show fit	0.11	ENST00000421715.2	IFNA4 Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 4
chr9_-_94640248 Show fit	0.11	ENST00000415431.5	FBP1 Ensembl NCBI GeneCards UniProt Show fit	fructose-bisphosphatase 1
chr16_+_32995048 Show fit	0.11	ENST00000425181.3	IGHV3OR16-10 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr11_-_19201976 Show fit	0.11	ENST00000647990.1 ENST00000649235.1 ENST00000265968.9 ENST00000649842.1	CSRP3 Ensembl NCBI GeneCards UniProt Show fit	cysteine and glycine rich protein 3
chr16_-_66918876 Show fit	0.11	ENST00000570262.5 ENST00000299752.9 ENST00000394055.7	CDH16 Ensembl NCBI GeneCards UniProt Show fit	cadherin 16
chr11_-_72642407 Show fit	0.11	ENST00000376450.7	PDE2A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 2A
chr5_+_81233314 Show fit	0.11	ENST00000511719.5 ENST00000437669.5 ENST00000254035.9 ENST00000424301.6 ENST00000505060.1	CKMT2 Ensembl NCBI GeneCards UniProt Show fit	creatine kinase, mitochondrial 2
chr9_-_21240002 Show fit	0.11	ENST00000380222.4	IFNA14 Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 14
chr16_+_28863812 Show fit	0.11	ENST00000684370.1	SH2B1 Ensembl NCBI GeneCards UniProt Show fit	SH2B adaptor protein 1
chr17_+_64506953 Show fit	0.11	ENST00000580188.1 ENST00000556440.7 ENST00000581056.5	CEP95 Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 95
chr7_+_74093079 Show fit	0.11	ENST00000538333.3	LIMK1 Ensembl NCBI GeneCards UniProt Show fit	LIM domain kinase 1
chr7_+_53035627 Show fit	0.11	ENST00000408890.6	POM121L12 Ensembl NCBI GeneCards UniProt Show fit	POM121 transmembrane nucleoporin like 12
chr9_-_21202205 Show fit	0.10	ENST00000239347.3	IFNA7 Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 7
chr16_+_33827140 Show fit	0.10	ENST00000562905.2	IGHV3OR16-13 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr15_+_45129933 Show fit	0.10	ENST00000321429.8 ENST00000389037.7 ENST00000558322.5	DUOX1 Ensembl NCBI GeneCards UniProt Show fit	dual oxidase 1
chr10_+_24466487 Show fit	0.10	ENST00000396446.5 ENST00000396445.5 ENST00000376451.4	KIAA1217 Ensembl NCBI GeneCards UniProt Show fit	KIAA1217
chrX_+_119399286 Show fit	0.10	ENST00000217909.8	SLC25A43 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 43
chr22_+_32357867 Show fit	0.10	ENST00000249007.4	RFPL3 Ensembl NCBI GeneCards UniProt Show fit	ret finger protein like 3
chr2_+_218672027 Show fit	0.10	ENST00000392105.7 ENST00000455724.5 ENST00000295709.8	STK36 Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 36
chr2_+_203936755 Show fit	0.10	ENST00000316386.11 ENST00000435193.1	ICOS Ensembl NCBI GeneCards UniProt Show fit	inducible T cell costimulator
chr17_-_8152380 Show fit	0.10	ENST00000317276.9	PER1 Ensembl NCBI GeneCards UniProt Show fit	period circadian regulator 1
chr12_-_14938508 Show fit	0.10	ENST00000266397.7	ERP27 Ensembl NCBI GeneCards UniProt Show fit	endoplasmic reticulum protein 27
chr3_+_111998915 Show fit	0.09	ENST00000478951.6	TAGLN3 Ensembl NCBI GeneCards UniProt Show fit	transgelin 3
chr11_-_17476801 Show fit	0.09	ENST00000644772.1 ENST00000642271.1 ENST00000684571.1 ENST00000646902.1 ENST00000647015.1 ENST00000302539.9 ENST00000389817.8 ENST00000643260.1 ENST00000683136.1	ABCC8 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily C member 8
chr12_+_8992029 Show fit	0.09	ENST00000543895.1	KLRG1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor G1
chr19_-_51390528 Show fit	0.09	ENST00000570516.1 ENST00000574814.2	C19orf84 Ensembl NCBI GeneCards UniProt Show fit	chromosome 19 open reading frame 84
chr3_+_158644510 Show fit	0.09	ENST00000486715.6 ENST00000478576.5 ENST00000264263.9 ENST00000464732.1	GFM1 Ensembl NCBI GeneCards UniProt Show fit	G elongation factor mitochondrial 1
chrX_-_32155462 Show fit	0.09	ENST00000359836.5 ENST00000378707.7 ENST00000541735.5 ENST00000684130.1 ENST00000682238.1 ENST00000620040.5 ENST00000474231.5	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr11_-_132943092 Show fit	0.09	ENST00000612177.4 ENST00000541867.5	OPCML Ensembl NCBI GeneCards UniProt Show fit	opioid binding protein/cell adhesion molecule like
chr14_-_63318933 Show fit	0.09	ENST00000621500.2	GPHB5 Ensembl NCBI GeneCards UniProt Show fit	glycoprotein hormone subunit beta 5
chr1_-_23424692 Show fit	0.09	ENST00000374601.7 ENST00000450454.7	TCEA3 Ensembl NCBI GeneCards UniProt Show fit	transcription elongation factor A3
chr1_+_40738834 Show fit	0.09	ENST00000525290.5 ENST00000530965.5 ENST00000416859.6 ENST00000308733.9	NFYC Ensembl NCBI GeneCards UniProt Show fit	nuclear transcription factor Y subunit gamma
chr3_-_139476508 Show fit	0.09	ENST00000232217.6	RBP2 Ensembl NCBI GeneCards UniProt Show fit	retinol binding protein 2
chr1_-_66801276 Show fit	0.08	ENST00000304526.3	INSL5 Ensembl NCBI GeneCards UniProt Show fit	insulin like 5
chr5_-_79512794 Show fit	0.08	ENST00000282260.10 ENST00000508576.5 ENST00000535690.1	HOMER1 Ensembl NCBI GeneCards UniProt Show fit	homer scaffold protein 1
chr3_+_111998739 Show fit	0.08	ENST00000393917.6 ENST00000273368.8	TAGLN3 Ensembl NCBI GeneCards UniProt Show fit	transgelin 3
chrX_-_31178220 Show fit	0.08	ENST00000681026.1	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr5_+_96936071 Show fit	0.08	ENST00000231368.10	LNPEP Ensembl NCBI GeneCards UniProt Show fit	leucyl and cystinyl aminopeptidase
chrX_-_31178149 Show fit	0.08	ENST00000679437.1	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr22_+_20858999 Show fit	0.08	ENST00000215730.12	SNAP29 Ensembl NCBI GeneCards UniProt Show fit	synaptosome associated protein 29
chr17_+_75476493 Show fit	0.07	ENST00000375248.9	TMEM94 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 94
chr12_-_85836372 Show fit	0.07	ENST00000361228.5	RASSF9 Ensembl NCBI GeneCards UniProt Show fit	Ras association domain family member 9
chr5_+_34929572 Show fit	0.07	ENST00000382021.2	DNAJC21 Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C21
chr6_-_87095059 Show fit	0.07	ENST00000369582.6 ENST00000610310.3 ENST00000630630.2 ENST00000627148.3 ENST00000625577.1	CGA Ensembl NCBI GeneCards UniProt Show fit	glycoprotein hormones, alpha polypeptide
chr14_-_106538331 Show fit	0.07	ENST00000390624.3	IGHV3-48 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-48
chr5_+_34929524 Show fit	0.07	ENST00000648817.1	DNAJC21 Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C21
chr5_+_141094595 Show fit	0.07	ENST00000622947.1 ENST00000194155.7 ENST00000624874.1 ENST00000625033.1	PCDHB2 Ensembl NCBI GeneCards UniProt Show fit	protocadherin beta 2
chr11_-_10693504 Show fit	0.07	ENST00000529547.1 ENST00000558540.5	IRAG1 Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-triphosphate receptor associated 1
chr14_+_35046238 Show fit	0.07	ENST00000280987.9	FAM177A1 Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 177 member A1
chr3_-_52154382 Show fit	0.06	ENST00000474012.1 ENST00000296484.7	POC1A Ensembl NCBI GeneCards UniProt Show fit	POC1 centriolar protein A
chr16_+_22490337 Show fit	0.06	ENST00000415833.6	NPIPB5 Ensembl NCBI GeneCards UniProt Show fit	nuclear pore complex interacting protein family member B5
chr4_+_140343443 Show fit	0.06	ENST00000338517.8 ENST00000394203.7 ENST00000506322.5	SCOC Ensembl NCBI GeneCards UniProt Show fit	short coiled-coil protein
chr12_+_120978686 Show fit	0.06	ENST00000541395.5 ENST00000544413.2	HNF1A Ensembl NCBI GeneCards UniProt Show fit	HNF1 homeobox A
chr20_-_45308297 Show fit	0.06	ENST00000353917.10 ENST00000360607.10	MATN4 Ensembl NCBI GeneCards UniProt Show fit	matrilin 4
chr17_+_48107743 Show fit	0.06	ENST00000359238.7 ENST00000582104.5 ENST00000584335.5	SNX11 Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 11
chr3_+_52779916 Show fit	0.06	ENST00000537050.5	ITIH1 Ensembl NCBI GeneCards UniProt Show fit	inter-alpha-trypsin inhibitor heavy chain 1
chr9_-_21166660 Show fit	0.06	ENST00000380225.1	IFNA21 Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 21
chr3_-_114624193 Show fit	0.06	ENST00000481632.5	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr10_-_15719885 Show fit	0.05	ENST00000378076.4	ITGA8 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha 8
chr8_+_103298836 Show fit	0.05	ENST00000523739.5 ENST00000358755.5	FZD6 Ensembl NCBI GeneCards UniProt Show fit	frizzled class receptor 6
chr3_+_63967738 Show fit	0.05	ENST00000484332.1	ATXN7 Ensembl NCBI GeneCards UniProt Show fit	ataxin 7
chr2_-_68319887 Show fit	0.05	ENST00000409862.1 ENST00000263655.4	CNRIP1 Ensembl NCBI GeneCards UniProt Show fit	cannabinoid receptor interacting protein 1
chr3_-_8769602 Show fit	0.05	ENST00000316793.8 ENST00000431493.1	OXTR Ensembl NCBI GeneCards UniProt Show fit	oxytocin receptor
chr4_-_68245683 Show fit	0.05	ENST00000332644.6	TMPRSS11B Ensembl NCBI GeneCards UniProt Show fit	transmembrane serine protease 11B
chr5_+_157180816 Show fit	0.05	ENST00000422843.8	ITK Ensembl NCBI GeneCards UniProt Show fit	IL2 inducible T cell kinase
chr11_-_132943671 Show fit	0.05	ENST00000331898.11	OPCML Ensembl NCBI GeneCards UniProt Show fit	opioid binding protein/cell adhesion molecule like
chr6_-_39322968 Show fit	0.05	ENST00000507712.5	KCNK16 Ensembl NCBI GeneCards UniProt Show fit	potassium two pore domain channel subfamily K member 16
chr14_-_106335613 Show fit	0.05	ENST00000603660.1	IGHV3-30 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-30
chr14_+_63204436 Show fit	0.05	ENST00000316754.8	RHOJ Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member J
chr6_+_52186373 Show fit	0.05	ENST00000648244.1	IL17A Ensembl NCBI GeneCards UniProt Show fit	interleukin 17A
chr2_-_63588390 Show fit	0.05	ENST00000272321.12 ENST00000409562.7	WDPCP Ensembl NCBI GeneCards UniProt Show fit	WD repeat containing planar cell polarity effector
chr17_+_48107549 Show fit	0.05	ENST00000580219.5 ENST00000452859.6 ENST00000393405.6	SNX11 Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 11
chr8_+_97887903 Show fit	0.05	ENST00000520016.5	MATN2 Ensembl NCBI GeneCards UniProt Show fit	matrilin 2
chr6_+_34466059 Show fit	0.05	ENST00000620693.4 ENST00000244458.7 ENST00000374043.6	PACSIN1 Ensembl NCBI GeneCards UniProt Show fit	protein kinase C and casein kinase substrate in neurons 1
chr7_-_157010615 Show fit	0.05	ENST00000252971.11	MNX1 Ensembl NCBI GeneCards UniProt Show fit	motor neuron and pancreas homeobox 1
chr3_-_115071333 Show fit	0.05	ENST00000462705.5	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chrX_-_130385656 Show fit	0.04	ENST00000276218.4 ENST00000682440.1	GPR119 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 119
chr18_-_46917432 Show fit	0.04	ENST00000324794.11 ENST00000545673.5 ENST00000585916.6	PIAS2 Ensembl NCBI GeneCards UniProt Show fit	protein inhibitor of activated STAT 2
chr4_+_15339818 Show fit	0.04	ENST00000397700.6 ENST00000295297.4	C1QTNF7 Ensembl NCBI GeneCards UniProt Show fit	C1q and TNF related 7
chr16_+_28863757 Show fit	0.04	ENST00000618521.4 ENST00000359285.9 ENST00000538342.5	SH2B1 Ensembl NCBI GeneCards UniProt Show fit	SH2B adaptor protein 1
chr21_+_32298945 Show fit	0.04	ENST00000339944.4	MRAP Ensembl NCBI GeneCards UniProt Show fit	melanocortin 2 receptor accessory protein
chr8_+_66429003 Show fit	0.04	ENST00000320270.4	RRS1 Ensembl NCBI GeneCards UniProt Show fit	ribosome biogenesis regulator 1 homolog
chr18_-_27143024 Show fit	0.04	ENST00000581714.5	CHST9 Ensembl NCBI GeneCards UniProt Show fit	carbohydrate sulfotransferase 9
chr12_+_65169546 Show fit	0.04	ENST00000308330.3	LEMD3 Ensembl NCBI GeneCards UniProt Show fit	LEM domain containing 3
chr15_-_51243011 Show fit	0.03	ENST00000405913.7 ENST00000559878.5	CYP19A1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 19 subfamily A member 1
chr6_-_70303070 Show fit	0.03	ENST00000370496.3 ENST00000357250.11	COL9A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type IX alpha 1 chain
chr7_-_36724543 Show fit	0.03	ENST00000612871.4	AOAH Ensembl NCBI GeneCards UniProt Show fit	acyloxyacyl hydrolase
chrX_-_111410420 Show fit	0.03	ENST00000371993.7 ENST00000680476.1	DCX Ensembl NCBI GeneCards UniProt Show fit	doublecortin
chr3_-_39051935 Show fit	0.03	ENST00000668754.1 ENST00000302328.9	SCN11A Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 11
chr22_-_36817510 Show fit	0.03	ENST00000443735.1	PVALB Ensembl NCBI GeneCards UniProt Show fit	parvalbumin
chr1_-_56966133 Show fit	0.03	ENST00000535057.5 ENST00000543257.5	C8B Ensembl NCBI GeneCards UniProt Show fit	complement C8 beta chain

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:1901876	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1	0.5	GO:0099558	maintenance of synapse structure(GO:0099558)
0.1	0.3	GO:0018874	benzoate metabolic process(GO:0018874)
0.1	0.7	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1	0.3	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.1	0.3	GO:0002086	diaphragm contraction(GO:0002086)
0.1	1.6	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1	0.2	GO:0036292	DNA rewinding(GO:0036292)
0.1	0.4	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.0	0.4	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.0	0.9	GO:0042424	catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	0.2	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.1	GO:0035674	tricarboxylic acid transmembrane transport(GO:0035674)
0.0	0.3	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.0	0.5	GO:0034465	response to carbon monoxide(GO:0034465)
0.0	0.1	GO:0001808	negative regulation of type IV hypersensitivity(GO:0001808)
0.0	0.9	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.2	GO:0035995	detection of muscle stretch(GO:0035995)
0.0	0.7	GO:0070986	left/right axis specification(GO:0070986)
0.0	0.1	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0	0.1	GO:0005986	sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986)
0.0	0.7	GO:0097186	amelogenesis(GO:0097186)
0.0	0.9	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0042335	cuticle development(GO:0042335)
0.0	0.2	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.0	0.1	GO:0007228	positive regulation of hh target transcription factor activity(GO:0007228)
0.0	0.1	GO:1905073	positive regulation of relaxation of muscle(GO:1901079) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0	0.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0	0.2	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0	0.1	GO:0072114	regulation of pronephros size(GO:0035565) pronephros morphogenesis(GO:0072114)
0.0	0.1	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.4	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.0	0.1	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.0	GO:0016476	regulation of embryonic cell shape(GO:0016476)
0.0	0.4	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.0	0.1	GO:0016240	autophagosome docking(GO:0016240)
0.0	0.2	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.2	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621)
0.0	0.3	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.1	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.0	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.0	GO:0033139	regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139)
0.0	0.3	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0	0.1	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.1	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.8	GO:0006910	phagocytosis, recognition(GO:0006910)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.6	GO:0032133	chromosome passenger complex(GO:0032133)
0.1	0.4	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.7	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.3	GO:1990584	cardiac Troponin complex(GO:1990584)
0.0	0.2	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.0	0.3	GO:0071953	elastic fiber(GO:0071953)
0.0	0.5	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0016013	syntrophin complex(GO:0016013)
0.0	0.1	GO:0031905	early endosome lumen(GO:0031905)
0.0	0.8	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	0.4	GO:0031143	pseudopodium(GO:0031143)
0.0	0.0	GO:1905103	integral component of lysosomal membrane(GO:1905103)
0.0	0.1	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	GO:0009019	tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1	0.9	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.1	0.5	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.1	0.4	GO:0051373	FATZ binding(GO:0051373)
0.0	0.9	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.2	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.3	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.1	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0	1.6	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.4	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.2	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.2	GO:0031433	telethonin binding(GO:0031433)
0.0	0.1	GO:0008281	sulfonylurea receptor activity(GO:0008281)
0.0	0.1	GO:0031531	thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0	0.2	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.3	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.2	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) TPR domain binding(GO:0030911)
0.0	0.3	GO:0031014	troponin T binding(GO:0031014)
0.0	0.5	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.2	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0	0.3	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.2	GO:1903136	cuprous ion binding(GO:1903136)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.8	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.6	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.7	PID PLK1 PATHWAY	PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.7	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
1.6	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation

Results for NKX2-8

Z-value: 0.55

Motif logo

Transcription factors associated with NKX2-8

Activity-expression correlation:

Activity profile of NKX2-8 motif

Sorted Z-values of NKX2-8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-8

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: