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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NKX6-2

Z-value: 0.73

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Transcription factors associated with NKX6-2

Gene Symbol Gene ID Gene Info
ENSG00000148826.9 NKX6-2

Activity profile of NKX6-2 motif

Sorted Z-values of NKX6-2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX6-2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr20_-_7940444 2.66 ENST00000378789.4
hydroxyacid oxidase 1
chr7_+_123601836 1.61 ENST00000434204.5
ankyrin repeat and SOCS box containing 15
chr1_+_244352627 1.27 ENST00000366537.5
ENST00000308105.5
chromosome 1 open reading frame 100
chr7_+_123601815 1.19 ENST00000451215.6
ankyrin repeat and SOCS box containing 15
chr4_+_87975667 0.96 ENST00000237623.11
ENST00000682655.1
ENST00000508233.6
ENST00000360804.4
ENST00000395080.8
secreted phosphoprotein 1
chr2_+_209579598 0.90 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr2_+_209579399 0.90 ENST00000360351.8
microtubule associated protein 2
chr5_+_31193678 0.86 ENST00000265071.3
cadherin 6
chr1_-_158554405 0.79 ENST00000641282.1
ENST00000641622.1
olfactory receptor family 6 subfamily Y member 1
chr5_+_31193739 0.78 ENST00000514738.5
cadherin 6
chr14_-_75063990 0.78 ENST00000555135.1
ENST00000357971.7
ENST00000553302.1
ENST00000238618.8
ENST00000555694.5
acylphosphatase 1
chr1_+_209704836 0.67 ENST00000367027.5
hydroxysteroid 11-beta dehydrogenase 1
chr7_-_84194781 0.65 ENST00000265362.9
semaphorin 3A
chr18_+_44680093 0.65 ENST00000426838.8
ENST00000677068.1
SET binding protein 1
chr1_-_145957969 0.63 ENST00000604000.4
limb and CNS expressed 1 like
chr12_+_6914571 0.60 ENST00000229277.6
ENST00000538763.5
ENST00000545045.6
enolase 2
chrX_+_136148440 0.60 ENST00000627383.2
ENST00000630084.2
four and a half LIM domains 1
chr2_+_210477708 0.59 ENST00000673711.1
carbamoyl-phosphate synthase 1
chr11_+_122882683 0.59 ENST00000307257.10
ENST00000227349.7
junctional cadherin complex regulator
chr2_+_210477676 0.58 ENST00000673510.1
ENST00000673630.1
ENST00000430249.7
carbamoyl-phosphate synthase 1
chr4_+_41256921 0.55 ENST00000284440.9
ENST00000508768.5
ENST00000512788.1
ubiquitin C-terminal hydrolase L1
chr17_-_7404039 0.55 ENST00000576017.1
ENST00000302422.4
transmembrane protein 256
chr2_+_209579429 0.53 ENST00000361559.8
microtubule associated protein 2
chr1_-_110391041 0.53 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
solute carrier family 16 member 4
chr2_+_11724333 0.51 ENST00000425416.6
ENST00000396097.5
lipin 1
chr1_-_110390989 0.51 ENST00000369779.9
ENST00000472422.6
solute carrier family 16 member 4
chr12_+_9827517 0.51 ENST00000537723.5
killer cell lectin like receptor F1
chr3_+_159839847 0.48 ENST00000445224.6
schwannomin interacting protein 1
chr2_-_55334529 0.47 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
coiled-coil domain containing 88A
chr12_+_9827472 0.45 ENST00000617793.4
ENST00000617889.5
ENST00000354855.7
ENST00000279545.7
killer cell lectin like receptor F1
chr3_+_39467672 0.44 ENST00000436143.6
ENST00000441980.6
ENST00000682069.1
ENST00000311042.10
myelin associated oligodendrocyte basic protein
chr22_-_28741783 0.44 ENST00000439200.5
ENST00000405598.5
ENST00000398017.3
ENST00000649563.1
ENST00000650281.1
ENST00000425190.7
ENST00000404276.6
ENST00000650233.1
ENST00000348295.7
ENST00000382580.6
checkpoint kinase 2
chr1_-_48776811 0.42 ENST00000371833.4
BEN domain containing 5
chr6_+_132538290 0.42 ENST00000434551.2
trace amine associated receptor 9
chr17_-_59155235 0.42 ENST00000581068.5
spindle and kinetochore associated complex subunit 2
chr18_-_48950960 0.41 ENST00000262158.8
SMAD family member 7
chr3_-_71132099 0.40 ENST00000650188.1
ENST00000648121.1
ENST00000648794.1
ENST00000649592.1
forkhead box P1
chr13_-_33185994 0.38 ENST00000255486.8
StAR related lipid transfer domain containing 13
chr1_-_114153863 0.37 ENST00000610222.3
ENST00000369547.6
ENST00000641643.2
synaptotagmin 6
chr3_-_142029108 0.37 ENST00000497579.5
transcription factor Dp-2
chr1_+_85062304 0.36 ENST00000326813.12
ENST00000528899.5
ENST00000294664.11
dynein axonemal intermediate chain 3
chr17_+_59155726 0.36 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
proline rich 11
chr1_+_174964750 0.36 ENST00000367688.3
RAB GTPase activating protein 1 like
chr2_+_232662733 0.36 ENST00000410095.5
ENST00000611312.1
EF-hand domain family member D1
chr12_-_52652207 0.36 ENST00000309680.4
keratin 2
chr7_+_120273129 0.35 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2
chr10_-_69409275 0.35 ENST00000373307.5
tachykinin receptor 2
chr2_-_207165923 0.34 ENST00000309446.11
Kruppel like factor 7
chr4_+_168497066 0.34 ENST00000261509.10
palladin, cytoskeletal associated protein
chr17_-_59151794 0.34 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr4_+_168497044 0.29 ENST00000505667.6
palladin, cytoskeletal associated protein
chr21_-_30487436 0.29 ENST00000334055.5
keratin associated protein 19-2
chr6_-_87095059 0.29 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr2_+_178284907 0.29 ENST00000409631.5
oxysterol binding protein like 6
chr6_+_26199509 0.29 ENST00000356530.5
H2B clustered histone 7
chr17_-_42676980 0.27 ENST00000587627.1
ENST00000591022.6
ENST00000293349.10
pleckstrin homology, MyTH4 and FERM domain containing H3
chr17_-_43758780 0.27 ENST00000301691.3
sclerostin
chr18_-_12656716 0.27 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
spire type actin nucleation factor 1
chr11_-_5227063 0.27 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chrX_+_154304923 0.27 ENST00000426989.5
ENST00000426203.5
ENST00000369912.2
transketolase like 1
chr5_-_58999885 0.27 ENST00000317118.12
phosphodiesterase 4D
chr16_-_46748337 0.26 ENST00000394809.9
myosin light chain kinase 3
chr7_-_36985060 0.25 ENST00000396040.6
engulfment and cell motility 1
chr7_+_77840122 0.25 ENST00000450574.5
ENST00000248550.7
putative homeodomain transcription factor 2
chr12_-_27971970 0.25 ENST00000395872.5
ENST00000201015.8
parathyroid hormone like hormone
chr9_-_23826299 0.25 ENST00000380117.5
ELAV like RNA binding protein 2
chr18_+_34710307 0.25 ENST00000679796.1
dystrobrevin alpha
chr12_-_56741535 0.24 ENST00000647707.1
novel protein
chr8_-_71356511 0.24 ENST00000419131.6
ENST00000388743.6
EYA transcriptional coactivator and phosphatase 1
chr6_-_79537423 0.24 ENST00000369846.9
ENST00000392959.5
ENST00000467898.3
lebercilin LCA5
chr11_-_62754141 0.24 ENST00000527994.1
ENST00000394807.5
ENST00000673933.1
zinc finger and BTB domain containing 3
chr3_+_39467598 0.24 ENST00000428261.5
ENST00000420739.5
ENST00000415443.5
ENST00000447324.5
ENST00000383754.7
myelin associated oligodendrocyte basic protein
chr11_-_14358450 0.23 ENST00000526063.5
ENST00000532814.5
RAS related 2
chr6_-_130956371 0.22 ENST00000639623.1
ENST00000525193.5
ENST00000527659.5
erythrocyte membrane protein band 4.1 like 2
chr7_+_101218146 0.22 ENST00000305105.3
zinc finger HIT-type containing 1
chr7_-_78771265 0.22 ENST00000630991.2
ENST00000629359.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr15_+_92900338 0.22 ENST00000625990.3
chromodomain helicase DNA binding protein 2
chr17_-_62808299 0.21 ENST00000311269.10
membrane associated ring-CH-type finger 10
chrX_+_35919725 0.21 ENST00000297866.9
ENST00000378653.8
cilia and flagella associated protein 47
chr6_-_26199272 0.21 ENST00000650491.1
ENST00000635200.1
ENST00000341023.2
novel protein
H2A clustered histone 7
chr3_-_142028597 0.21 ENST00000467667.5
transcription factor Dp-2
chr17_-_62808339 0.20 ENST00000583600.5
membrane associated ring-CH-type finger 10
chr15_+_49423233 0.20 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
fibroblast growth factor 7
chr3_+_130931893 0.20 ENST00000504612.5
ATPase secretory pathway Ca2+ transporting 1
chr2_-_136116165 0.20 ENST00000409817.1
C-X-C motif chemokine receptor 4
chr17_-_59155164 0.19 ENST00000583380.5
ENST00000580541.1
ENST00000578105.1
ENST00000330137.12
ENST00000437036.6
spindle and kinetochore associated complex subunit 2
chr17_+_29941605 0.19 ENST00000394835.7
EF-hand calcium binding domain 5
chr5_+_156326735 0.19 ENST00000435422.7
sarcoglycan delta
chr10_-_99235783 0.19 ENST00000370546.5
ENST00000614306.1
heparanase 2 (inactive)
chr1_+_244461270 0.19 ENST00000366534.9
catsper channel auxiliary subunit epsilon
chr16_-_67483541 0.18 ENST00000290953.3
agouti related neuropeptide
chr5_+_161848314 0.18 ENST00000437025.6
gamma-aminobutyric acid type A receptor subunit alpha1
chr1_+_244461370 0.18 ENST00000366531.7
catsper channel auxiliary subunit epsilon
chr1_+_244461386 0.18 ENST00000366533.8
ENST00000428042.1
catsper channel auxiliary subunit epsilon
chr19_-_57457140 0.18 ENST00000321039.5
vomeronasal 1 receptor 1
chr3_+_68004231 0.17 ENST00000478136.6
TAFA chemokine like family member 1
chr1_+_100345018 0.17 ENST00000635056.2
ENST00000647005.1
cell division cycle 14A
chr4_-_151227881 0.16 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr17_-_58417547 0.16 ENST00000577716.5
ring finger protein 43
chr14_-_26597430 0.16 ENST00000344429.9
ENST00000574031.1
ENST00000465357.6
ENST00000547619.5
NOVA alternative splicing regulator 1
chrX_-_81201886 0.16 ENST00000451455.1
ENST00000358130.7
ENST00000436386.5
high mobility group nucleosome binding domain 5
chrX_+_106693838 0.16 ENST00000324342.7
ring finger protein 128
chr17_-_58417521 0.16 ENST00000584437.5
ENST00000407977.7
ring finger protein 43
chr7_-_102642791 0.16 ENST00000340457.8
uroplakin 3B like 1
chr21_-_30492008 0.16 ENST00000334063.6
keratin associated protein 19-3
chr1_-_150876697 0.15 ENST00000515192.5
aryl hydrocarbon receptor nuclear translocator
chr11_-_31509588 0.15 ENST00000534812.5
ENST00000529749.5
ENST00000532287.6
ENST00000278200.5
ENST00000530023.5
ENST00000533642.1
inner mitochondrial membrane peptidase subunit 1
chr8_+_26293112 0.15 ENST00000523925.5
ENST00000315985.7
protein phosphatase 2 regulatory subunit Balpha
chr7_-_22193824 0.15 ENST00000401957.6
Rap guanine nucleotide exchange factor 5
chr15_+_64387828 0.15 ENST00000261884.8
thyroid hormone receptor interactor 4
chr14_+_88385643 0.14 ENST00000393545.9
ENST00000356583.9
ENST00000555401.5
ENST00000553885.5
spermatogenesis associated 7
chr2_+_190649062 0.14 ENST00000409581.5
ENST00000337386.10
NGFI-A binding protein 1
chr14_-_59630806 0.13 ENST00000342503.8
reticulon 1
chr6_+_113857333 0.13 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr18_-_3219961 0.13 ENST00000356443.9
myomesin 1
chr1_-_243163310 0.12 ENST00000492145.1
ENST00000490813.5
ENST00000464936.5
centrosomal protein 170
chr6_-_63319943 0.12 ENST00000622415.1
ENST00000370658.9
ENST00000485906.6
ENST00000370657.9
lengsin, lens protein with glutamine synthetase domain
chr8_+_78516329 0.12 ENST00000396418.7
ENST00000352966.9
cAMP-dependent protein kinase inhibitor alpha
chr1_+_156126160 0.12 ENST00000448611.6
ENST00000368297.5
lamin A/C
chr10_+_88586762 0.12 ENST00000371939.7
lipase family member J
chr20_+_43507668 0.12 ENST00000434666.5
ENST00000649084.1
ENST00000418998.7
ENST00000427442.8
ENST00000649917.1
L3MBTL histone methyl-lysine binding protein 1
chr4_+_54229261 0.11 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chr9_+_85941121 0.11 ENST00000361671.10
N-alpha-acetyltransferase 35, NatC auxiliary subunit
chr18_+_75210755 0.11 ENST00000322038.5
teashirt zinc finger homeobox 1
chr6_+_47698574 0.11 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr18_+_75210789 0.11 ENST00000580243.3
teashirt zinc finger homeobox 1
chr12_-_76068933 0.11 ENST00000552056.5
nucleosome assembly protein 1 like 1
chr2_+_172928165 0.11 ENST00000535187.5
Rap guanine nucleotide exchange factor 4
chr11_-_55936400 0.11 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr11_-_13496018 0.10 ENST00000529816.1
parathyroid hormone
chr1_-_226739271 0.10 ENST00000429204.6
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr4_-_89838289 0.10 ENST00000336904.7
synuclein alpha
chr15_+_92900189 0.10 ENST00000626874.2
ENST00000627622.1
ENST00000629346.2
ENST00000628375.2
ENST00000420239.7
ENST00000394196.9
chromodomain helicase DNA binding protein 2
chr4_+_187995764 0.10 ENST00000509524.5
ENST00000326866.5
ZFP42 zinc finger protein
chr14_+_88385714 0.10 ENST00000045347.11
spermatogenesis associated 7
chr3_-_98522514 0.10 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr5_+_161848112 0.10 ENST00000393943.10
gamma-aminobutyric acid type A receptor subunit alpha1
chr6_+_47698538 0.10 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr14_-_59630582 0.10 ENST00000395090.5
reticulon 1
chr10_+_49679637 0.10 ENST00000374113.3
ENST00000374111.8
ENST00000374112.7
ENST00000535836.1
chromosome 10 open reading frame 53
chr9_-_23826231 0.10 ENST00000397312.7
ELAV like RNA binding protein 2
chr11_-_13495984 0.10 ENST00000282091.6
parathyroid hormone
chr8_-_90082871 0.09 ENST00000265431.7
calbindin 1
chrX_-_31178220 0.09 ENST00000681026.1
dystrophin
chr19_-_51082883 0.09 ENST00000650543.2
kallikrein related peptidase 14
chr17_-_75667088 0.09 ENST00000578201.5
ENST00000423245.6
ENST00000317905.10
RecQ like helicase 5
chrX_-_31178149 0.09 ENST00000679437.1
dystrophin
chr8_+_96584920 0.09 ENST00000521590.5
syndecan 2
chr3_-_15798184 0.09 ENST00000624145.3
ankyrin repeat domain 28
chr1_-_221742074 0.09 ENST00000366899.4
dual specificity phosphatase 10
chr17_-_69060906 0.08 ENST00000495634.5
ENST00000453985.6
ENST00000340001.9
ENST00000585714.1
ATP binding cassette subfamily A member 9
chr6_+_41053194 0.08 ENST00000244669.3
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr1_-_88891496 0.08 ENST00000448623.5
ENST00000370500.10
ENST00000418217.1
general transcription factor IIB
chr12_+_28257195 0.08 ENST00000381259.5
coiled-coil domain containing 91
chr3_-_147406520 0.08 ENST00000463250.1
ENST00000383075.8
Zic family member 4
chr2_+_108378176 0.08 ENST00000409309.3
sulfotransferase family 1C member 4
chr4_-_139280179 0.07 ENST00000398955.2
mitochondria localized glutamic acid rich protein
chr2_-_162536955 0.07 ENST00000621889.1
potassium voltage-gated channel subfamily H member 7
chr7_-_137343752 0.07 ENST00000393083.2
pleiotrophin
chr1_+_107139996 0.07 ENST00000370073.6
ENST00000370074.8
netrin G1
chr19_-_48716827 0.07 ENST00000595591.1
ENST00000356751.8
ENST00000594582.1
MEF2 activating motif and SAP domain containing transcriptional regulator
chr15_-_66356672 0.06 ENST00000261881.9
TIMELESS interacting protein
chrX_+_83508284 0.06 ENST00000644024.2
POU class 3 homeobox 4
chr2_-_178108339 0.06 ENST00000358450.8
phosphodiesterase 11A
chr3_+_178558700 0.06 ENST00000432997.5
ENST00000455865.5
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr8_-_108787563 0.06 ENST00000297459.4
transmembrane protein 74
chr2_+_108377947 0.06 ENST00000272452.7
sulfotransferase family 1C member 4
chr3_-_142028617 0.06 ENST00000477292.5
ENST00000478006.5
ENST00000495310.5
ENST00000486111.5
transcription factor Dp-2
chr12_+_121803991 0.06 ENST00000604567.6
ENST00000542440.5
SET domain containing 1B, histone lysine methyltransferase
chr16_+_56191476 0.06 ENST00000262493.12
G protein subunit alpha o1
chr9_+_107306459 0.05 ENST00000457811.1
RAD23 homolog B, nucleotide excision repair protein
chr12_-_109021015 0.05 ENST00000546618.2
ENST00000610966.5
SV2 related protein
chr18_+_34710249 0.05 ENST00000680346.1
ENST00000348997.9
ENST00000681274.1
ENST00000680822.1
ENST00000680767.2
ENST00000597599.5
ENST00000444659.6
dystrobrevin alpha
chr21_-_26090035 0.05 ENST00000448850.5
amyloid beta precursor protein
chr8_-_56211257 0.05 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1 zinc finger
chr6_+_3258914 0.05 ENST00000438998.7
ENST00000419065.6
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
proteasome assembly chaperone 4
chrX_-_103832204 0.05 ENST00000674363.1
ENST00000674162.1
ENST00000674338.1
ENST00000674274.1
ENST00000674271.1
ENST00000674265.1
ENST00000674212.1
ENST00000674255.1
ENST00000674342.1
ENST00000674430.1
ENST00000243298.3
novel transcript
RAB9B, member RAS oncogene family
chr18_-_33136075 0.05 ENST00000581852.5
coiled-coil domain containing 178
chr13_+_53028806 0.05 ENST00000219022.3
olfactomedin 4
chr17_-_75667165 0.05 ENST00000584999.1
ENST00000420326.6
ENST00000340830.9
RecQ like helicase 5
chr14_+_34993240 0.04 ENST00000677647.1
signal recognition particle 54
chr3_+_141262614 0.04 ENST00000504264.5
2-phosphoxylose phosphatase 1
chr3_+_52211442 0.04 ENST00000459884.1
5'-aminolevulinate synthase 1
chr19_+_4402615 0.03 ENST00000301280.10
chromatin assembly factor 1 subunit A
chr1_+_149886906 0.03 ENST00000331380.4
H2A clustered histone 20
chr5_+_162067858 0.03 ENST00000361925.9
gamma-aminobutyric acid type A receptor subunit gamma2
chr22_-_40533808 0.03 ENST00000422851.1
ENST00000651694.1
ENST00000652095.2
myocardin related transcription factor A
chr4_-_99657820 0.03 ENST00000511828.2
chromosome 4 open reading frame 54
chr14_-_64338096 0.03 ENST00000554572.5
ENST00000358599.9
estrogen receptor 2
chr2_-_190250503 0.03 ENST00000409820.2
ENST00000410045.5
3-hydroxyisobutyryl-CoA hydrolase
chr7_+_77696423 0.03 ENST00000334955.13
round spermatid basic protein 1 like
chr6_+_3258888 0.03 ENST00000380305.4
proteasome assembly chaperone 4
chr16_+_84768246 0.03 ENST00000569925.1
ENST00000567526.1
ubiquitin specific peptidase 10
chr11_+_57761787 0.03 ENST00000358694.10
ENST00000361332.8
ENST00000361391.10
ENST00000361796.9
ENST00000415361.6
ENST00000426142.6
ENST00000428599.6
ENST00000525902.5
ENST00000526357.5
ENST00000526772.5
ENST00000527467.5
ENST00000528232.5
ENST00000528621.5
ENST00000529526.5
ENST00000529873.5
ENST00000529986.5
ENST00000530094.5
ENST00000530748.5
ENST00000531014.5
ENST00000532245.5
ENST00000532463.5
ENST00000532649.5
ENST00000532787.5
ENST00000532844.5
ENST00000533667.5
ENST00000534579.5
ENST00000399050.10
ENST00000526938.5
ENST00000674015.1
ENST00000531007.2
ENST00000673826.1
catenin delta 1
chr6_+_116529013 0.03 ENST00000628083.1
ENST00000368597.6
ENST00000452373.5
ENST00000405399.5
calcium homeostasis modulator family member 4
chr2_+_206159884 0.02 ENST00000392222.7
eukaryotic translation elongation factor 1 beta 2
chrX_-_49043345 0.02 ENST00000315869.8
transcription factor binding to IGHM enhancer 3
chr5_-_146878595 0.02 ENST00000394409.7
protein phosphatase 2 regulatory subunit Bbeta
chr1_-_113871665 0.02 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
protein tyrosine phosphatase non-receptor type 22
chr2_+_206159580 0.02 ENST00000236957.9
ENST00000392221.5
ENST00000445505.5
eukaryotic translation elongation factor 1 beta 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.3 2.7 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 1.0 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.4 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.6 GO:0021828 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) sensory system development(GO:0048880) facioacoustic ganglion development(GO:1903375)
0.1 0.6 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.5 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.4 GO:0035106 operant conditioning(GO:0035106)
0.1 0.3 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.1 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.3 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.4 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 0.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.7 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0060437 lung growth(GO:0060437)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.3 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.4 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:1904397 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0051622 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.6 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.6 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 2.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 1.2 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.3 1.2 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 0.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.4 GO:0016497 substance K receptor activity(GO:0016497)
0.1 0.6 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 2.5 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0030305 heparanase activity(GO:0030305)
0.1 1.0 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.3 GO:0004802 transketolase activity(GO:0004802)
0.1 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.3 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 3.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis