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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR1H4

Z-value: 0.89

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Transcription factors associated with NR1H4

Gene Symbol Gene ID Gene Info
ENSG00000012504.15 NR1H4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1H4hg38_v1_chr12_+_100473916_1004739270.241.9e-01Click!

Activity profile of NR1H4 motif

Sorted Z-values of NR1H4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1H4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chrX_+_107206605 6.14 ENST00000372453.8
dynein axonemal assembly factor 6
chrX_+_107206632 6.14 ENST00000535523.5
ENST00000673764.1
dynein axonemal assembly factor 6
chr9_-_135499846 6.10 ENST00000429260.7
chromosome 9 open reading frame 116
chr3_-_50345665 5.97 ENST00000442887.1
ENST00000231749.8
ENST00000360165.7
zinc finger MYND-type containing 10
chr9_-_34381578 5.67 ENST00000379133.7
chromosome 9 open reading frame 24
chr9_-_34381531 5.66 ENST00000379124.5
ENST00000379126.7
ENST00000379127.1
chromosome 9 open reading frame 24
chr13_+_30932638 3.68 ENST00000380473.8
testis expressed 26
chrX_+_153072454 3.36 ENST00000421798.5
PNMA family member 6A
chr5_-_16508788 2.87 ENST00000682142.1
reticulophagy regulator 1
chr5_-_16508990 2.78 ENST00000399793.6
reticulophagy regulator 1
chr19_+_50203607 2.47 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr7_-_151024423 2.30 ENST00000469530.4
ENST00000639579.1
autophagy related 9B
chr13_-_26052009 2.28 ENST00000319420.4
shisa family member 2
chr1_+_162381703 2.24 ENST00000458626.4
chromosome 1 open reading frame 226
chr1_+_61082702 2.14 ENST00000485903.6
ENST00000371185.6
ENST00000371184.6
nuclear factor I A
chr19_-_49808639 1.91 ENST00000529634.2
fuzzy planar cell polarity protein
chr1_+_61082398 1.77 ENST00000664149.1
nuclear factor I A
chr19_+_35138778 1.74 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD domain containing ion transport regulator 1
novel transcript
chr14_-_21023954 1.52 ENST00000554094.5
NDRG family member 2
chr1_+_61082553 1.52 ENST00000403491.8
ENST00000371187.7
nuclear factor I A
chr6_-_49713521 1.50 ENST00000339139.5
cysteine rich secretory protein 2
chr14_-_21024092 1.49 ENST00000554398.5
NDRG family member 2
chr16_-_67666692 1.45 ENST00000602644.5
ENST00000243878.9
enkurin domain containing 1
chr11_+_45847406 1.39 ENST00000443527.6
ENST00000616623.4
ENST00000616080.2
cryptochrome circadian regulator 2
chr11_+_113314569 1.39 ENST00000429951.5
ENST00000442859.5
ENST00000531164.5
ENST00000529850.5
ENST00000529221.6
ENST00000525965.5
tetratricopeptide repeat domain 12
chr7_+_94509793 1.35 ENST00000297273.9
CAS1 domain containing 1
chr1_+_151511376 1.30 ENST00000427934.2
ENST00000271636.12
cingulin
chr19_+_10452891 1.25 ENST00000344979.7
phosphodiesterase 4A
chr11_-_69704013 1.21 ENST00000294312.4
fibroblast growth factor 19
chr11_-_116792386 1.17 ENST00000433069.2
ENST00000542499.5
apolipoprotein A5
chr11_+_113314811 1.17 ENST00000393020.5
tetratricopeptide repeat domain 12
chrX_-_107206426 1.15 ENST00000372466.8
ENST00000421752.1
nucleoporin 62 C-terminal like
chr17_-_47957824 1.14 ENST00000300557.3
proline rich 15 like
chr22_+_44677044 1.08 ENST00000006251.11
proline rich 5
chr5_+_134114673 1.08 ENST00000342854.10
ENST00000395029.5
transcription factor 7
chr22_+_44677077 1.08 ENST00000403581.5
proline rich 5
chr7_-_150341615 1.03 ENST00000223271.8
ENST00000466675.5
ENST00000482669.1
ENST00000467793.5
retinoic acid receptor responder 2
chr5_-_16508858 1.02 ENST00000684456.1
reticulophagy regulator 1
chr22_+_44676808 1.00 ENST00000624862.3
proline rich 5
chr19_-_44356664 0.97 ENST00000354340.9
ENST00000337401.8
ENST00000587909.1
zinc finger protein 112
chr8_+_109334317 0.95 ENST00000521662.5
ENST00000520147.5
ENST00000521688.6
ENY2 transcription and export complex 2 subunit
chr3_+_186842687 0.95 ENST00000444204.2
ENST00000320741.7
adiponectin, C1Q and collagen domain containing
chr5_-_140564550 0.95 ENST00000357560.9
ENST00000358580.9
amyloid beta precursor protein binding family B member 3
chr5_-_16508812 0.94 ENST00000683414.1
reticulophagy regulator 1
chr3_+_184337591 0.94 ENST00000383847.7
family with sequence similarity 131 member A
chr5_-_16508951 0.94 ENST00000682628.1
reticulophagy regulator 1
chr12_+_6789508 0.94 ENST00000011653.9
ENST00000541982.5
ENST00000539492.1
CD4 molecule
chr1_-_53945567 0.92 ENST00000371378.6
heat shock protein family B (small) member 11
chr14_-_23286082 0.92 ENST00000357460.7
homeobox and leucine zipper encoding
chr1_-_53945584 0.91 ENST00000371377.3
heat shock protein family B (small) member 11
chr8_-_100309368 0.90 ENST00000523167.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr18_-_12377200 0.88 ENST00000269143.8
AFG3 like matrix AAA peptidase subunit 2
chrX_-_133415478 0.84 ENST00000370828.4
glypican 4
chr3_-_160399207 0.82 ENST00000465537.5
ENST00000486856.5
ENST00000468218.5
ENST00000478370.5
ENST00000326448.12
intraflagellar transport 80
chr9_-_34372832 0.81 ENST00000379142.3
myogenesis regulating glycosidase (putative)
chr2_-_24972032 0.80 ENST00000534855.5
DnaJ heat shock protein family (Hsp40) member C27
chr15_+_65045377 0.77 ENST00000334287.3
solute carrier family 51 subunit beta
chr3_+_190388120 0.72 ENST00000456423.2
ENST00000264734.3
claudin 16
chr6_-_109094819 0.71 ENST00000436639.6
sestrin 1
chr12_-_7128873 0.70 ENST00000542370.1
ENST00000266560.8
retinol binding protein 5
chr6_+_107028188 0.69 ENST00000311381.8
ENST00000405204.6
mitochondrial transcription rescue factor 1
chr14_-_24634160 0.65 ENST00000616551.1
ENST00000382542.5
ENST00000216341.9
ENST00000526004.1
ENST00000415355.7
granzyme B
chr20_+_63738270 0.63 ENST00000467211.1
novel transcript, LIME1-SLC2A4RG readthrough
chr3_+_54123452 0.63 ENST00000620722.4
ENST00000490478.5
calcium voltage-gated channel auxiliary subunit alpha2delta 3
chr3_+_119147375 0.62 ENST00000490594.2
novel chromosome 3 open reading frame 30 (C3orf30) and uroplakin 1B (UPK1B)
chr22_+_31753867 0.61 ENST00000535622.6
ENST00000645693.1
ENST00000642974.1
ENST00000645711.1
ENST00000644331.1
ENST00000645560.1
ENST00000437411.6
ENST00000433147.2
ENST00000646755.1
ENST00000382112.8
ENST00000647438.1
ENST00000400248.7
ENST00000456178.6
ENST00000646969.1
ENST00000642696.1
ENST00000647343.1
ENST00000400242.8
ENST00000651528.2
ENST00000645015.1
ENST00000645564.1
ENST00000646465.1
ENST00000400249.7
DEP domain containing 5, GATOR1 subcomplex subunit
chr1_+_205257180 0.61 ENST00000330675.12
transmembrane and coiled-coil domain family 2
chr17_-_10036741 0.60 ENST00000585266.5
growth arrest specific 7
chr10_-_93601228 0.57 ENST00000371464.8
retinol binding protein 4
chr6_-_32192630 0.57 ENST00000375040.8
G protein signaling modulator 3
chr4_+_25914171 0.56 ENST00000506197.2
small integral membrane protein 20
chr4_+_25914275 0.55 ENST00000514384.1
small integral membrane protein 20
chr12_+_57520959 0.53 ENST00000551351.5
methyl-CpG binding domain protein 6
chr3_+_49021071 0.52 ENST00000395458.6
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr19_-_48363914 0.51 ENST00000377431.6
ENST00000293261.8
transmembrane protein 143
chr2_-_74553049 0.50 ENST00000409549.5
lysyl oxidase like 3
chr1_+_26234157 0.49 ENST00000640292.2
ENST00000451429.8
ENST00000252992.8
centrosomal protein 85
chr14_-_24634266 0.49 ENST00000382540.5
granzyme B
chr14_+_23555983 0.49 ENST00000404535.3
thiamine triphosphatase
chr7_-_78771265 0.47 ENST00000630991.2
ENST00000629359.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr19_-_3062464 0.47 ENST00000327141.9
TLE family member 5, transcriptional modulator
chr12_-_56333893 0.46 ENST00000547572.1
ENST00000257931.9
ENST00000610546.4
ENST00000440411.7
poly(A) specific ribonuclease subunit PAN2
chr17_-_42745025 0.46 ENST00000592492.5
ENST00000585893.5
ENST00000593214.5
ENST00000590078.5
ENST00000428826.7
ENST00000586382.5
ENST00000415827.6
ENST00000592743.5
ENST00000586089.5
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr11_-_7020235 0.45 ENST00000536068.5
ENST00000278314.5
zinc finger protein 214
chr2_-_218568291 0.45 ENST00000418019.5
ENST00000454775.5
ENST00000338465.5
ENST00000415516.5
ENST00000258399.8
ubiquitin specific peptidase 37
chr19_-_3062772 0.44 ENST00000586742.5
TLE family member 5, transcriptional modulator
chr12_-_56333693 0.44 ENST00000425394.7
ENST00000548043.5
poly(A) specific ribonuclease subunit PAN2
chr3_+_179562886 0.43 ENST00000450518.6
ENST00000392662.5
ENST00000429709.7
ENST00000490364.1
actin like 6A
chr19_-_48364034 0.43 ENST00000435956.7
transmembrane protein 143
chr11_-_707063 0.42 ENST00000683307.1
DEAF1 transcription factor
chr16_+_30664334 0.42 ENST00000287468.5
fibrosin
chr19_+_35031263 0.42 ENST00000640135.1
ENST00000596348.2
sodium voltage-gated channel beta subunit 1
chr17_-_29294141 0.42 ENST00000225388.9
nuclear FMR1 interacting protein 2
chr22_+_29307005 0.40 ENST00000406549.7
ENST00000610653.4
ENST00000621062.4
ENST00000611648.2
ENST00000618518.3
growth arrest specific 2 like 1
chr6_+_31655888 0.40 ENST00000375916.4
apolipoprotein M
chr3_-_49021045 0.39 ENST00000440857.5
DALR anticodon binding domain containing 3
chr5_+_141208697 0.38 ENST00000624949.1
ENST00000622978.1
ENST00000239450.4
protocadherin beta 12
chr22_+_30694886 0.37 ENST00000446658.6
oxysterol binding protein 2
chr22_+_29767351 0.37 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr5_+_141199555 0.36 ENST00000624887.1
ENST00000354757.5
protocadherin beta 11
chr4_-_142474395 0.35 ENST00000507861.5
inositol polyphosphate-4-phosphatase type II B
chr3_-_58666765 0.34 ENST00000358781.7
FAM3 metabolism regulating signaling molecule D
chr19_-_3063101 0.33 ENST00000221561.12
TLE family member 5, transcriptional modulator
chr11_-_71928624 0.33 ENST00000533047.5
ENST00000529844.5
novel protein similar to transient receptor potential cation channel, subfamily C, member 2 TRPC2
chr11_-_89491131 0.33 ENST00000343727.9
ENST00000531342.5
ENST00000375979.7
NADPH oxidase 4
chr12_+_108880085 0.33 ENST00000228476.8
ENST00000547768.5
D-amino acid oxidase
chr11_-_4393650 0.32 ENST00000254436.8
tripartite motif containing 21
chr6_-_106325735 0.32 ENST00000635758.2
ENST00000369076.8
ENST00000636437.1
autophagy related 5
chr16_+_66961242 0.32 ENST00000394037.5
ENST00000303334.9
carboxylesterase 3
chr3_-_15333152 0.32 ENST00000426925.5
SH3 domain binding protein 5
chr14_+_23556253 0.32 ENST00000556015.5
ENST00000554970.1
ENST00000288014.7
ENST00000554789.1
thiamine triphosphatase
chr1_-_16613481 0.31 ENST00000430580.6
ENST00000432949.5
NBPF member 1
chrX_-_48071613 0.31 ENST00000428686.1
ENST00000627643.2
ENST00000276054.9
ENST00000442455.8
zinc finger protein 630
chr1_+_25272492 0.31 ENST00000454452.6
Rh blood group D antigen
chr2_-_178072751 0.30 ENST00000286063.11
phosphodiesterase 11A
chr17_+_17782108 0.29 ENST00000395774.1
retinoic acid induced 1
chr9_-_71911183 0.29 ENST00000333421.7
abhydrolase domain containing 17B, depalmitoylase
chr5_+_139293728 0.29 ENST00000510056.5
ENST00000511249.5
ENST00000394805.8
ENST00000503811.5
ENST00000618441.5
matrin 3
chr12_-_15882261 0.29 ENST00000646918.1
ENST00000647087.1
ENST00000535752.5
epidermal growth factor receptor pathway substrate 8
chr19_+_1071194 0.28 ENST00000543365.5
Rho GTPase activating protein 45
chr6_-_106325616 0.27 ENST00000360666.6
autophagy related 5
chr15_+_86079863 0.27 ENST00000614907.3
ENST00000441037.7
ATP/GTP binding protein like 1
chrX_+_153724847 0.26 ENST00000218104.6
ATP binding cassette subfamily D member 1
chr8_-_115492221 0.25 ENST00000518018.1
transcriptional repressor GATA binding 1
chr6_+_127266875 0.24 ENST00000610162.5
ENST00000608991.5
ENST00000610153.1
ring finger protein 146
chrX_-_119693150 0.24 ENST00000394610.7
septin 6
chr3_-_160399512 0.23 ENST00000498409.5
ENST00000475677.5
ENST00000478536.1
intraflagellar transport 80
chr3_-_120742506 0.23 ENST00000273375.8
ENST00000483733.1
RAB, member of RAS oncogene family like 3
chr17_-_38563986 0.23 ENST00000622519.4
SRC kinase signaling inhibitor 1
chr1_+_36224410 0.22 ENST00000469141.6
ENST00000648638.1
ENST00000354618.10
thyroid hormone receptor associated protein 3
chr6_+_127266832 0.22 ENST00000356799.6
ENST00000368314.6
ring finger protein 146
chr9_-_114682172 0.22 ENST00000436752.3
testis expressed 48
chr19_+_10086787 0.21 ENST00000590378.5
ENST00000397881.7
shiftless antiviral inhibitor of ribosomal frameshifting
chr18_+_56651335 0.21 ENST00000589935.1
ENST00000254442.8
ENST00000357574.7
WD repeat domain 7
chr2_+_70900546 0.21 ENST00000234392.3
ventral anterior homeobox 2
chr13_+_27270814 0.21 ENST00000241463.5
RAS like family 11 member A
chr5_+_163503075 0.20 ENST00000280969.9
methionine adenosyltransferase 2B
chr1_-_158426237 0.20 ENST00000641042.1
olfactory receptor family 10 subfamily K member 2
chr6_-_106325416 0.19 ENST00000343245.7
autophagy related 5
chr9_+_71911468 0.19 ENST00000377031.7
chromosome 9 open reading frame 85
chr9_-_114682061 0.18 ENST00000612244.5
testis expressed 48
chr4_-_170089930 0.18 ENST00000337664.9
aminoadipate aminotransferase
chr17_-_2711633 0.17 ENST00000435359.5
clustered mitochondria homolog
chr4_-_169757873 0.17 ENST00000393381.3
histone PARylation factor 1
chr7_+_99504950 0.17 ENST00000394170.6
zinc finger with KRAB and SCAN domains 5
chr1_+_22563460 0.17 ENST00000166244.8
ENST00000374644.8
EPH receptor A8
chr20_+_32052192 0.15 ENST00000375862.7
ENST00000629881.2
ENST00000375852.5
ENST00000520553.5
ENST00000518730.5
HCK proto-oncogene, Src family tyrosine kinase
chr19_+_19385815 0.15 ENST00000494516.6
ENST00000360315.7
GATA zinc finger domain containing 2A
chr19_-_35135180 0.14 ENST00000392225.7
leucine rich repeat LGI family member 4
chr5_+_139293700 0.14 ENST00000504045.5
ENST00000504311.5
ENST00000502499.5
matrin 3
chr7_-_105679089 0.14 ENST00000477775.5
ataxin 7 like 1
chr17_+_7630094 0.14 ENST00000441599.6
ENST00000380450.9
ENST00000416273.7
ENST00000575903.5
ENST00000571153.5
ENST00000575618.5
ENST00000576152.1
ENST00000576830.5
sex hormone binding globulin
chr9_-_137221323 0.14 ENST00000391553.2
ENST00000392827.2
ring finger protein 208
chr1_+_32765667 0.14 ENST00000373480.1
KIAA1522
chr17_+_17681449 0.14 ENST00000353383.6
retinoic acid induced 1
chr11_-_71928437 0.13 ENST00000529513.5
novel protein similar to transient receptor potential cation channel, subfamily C, member 2 TRPC2
chr19_-_18274411 0.12 ENST00000595654.6
ENST00000593659.5
ENST00000599528.1
ENST00000392413.5
ENST00000608950.1
ENST00000600328.7
ENST00000600359.7
ENST00000612316.4
IQ motif containing N
chr4_+_122152308 0.12 ENST00000679879.1
ENST00000264501.8
KIAA1109
chr17_-_28552549 0.12 ENST00000581945.1
ENST00000444148.1
ENST00000335765.9
ENST00000301032.8
unc-119 lipid binding chaperone
chr1_+_178513103 0.12 ENST00000319416.7
ENST00000367643.7
ENST00000367642.3
ENST00000367641.7
ENST00000367639.1
testis expressed 35
chr14_-_21476874 0.12 ENST00000649801.1
ENST00000397762.6
RAB2B, member RAS oncogene family
chr4_-_174263080 0.12 ENST00000615392.4
F-box protein 8
chr11_-_89491320 0.11 ENST00000534731.5
ENST00000527626.5
ENST00000525196.5
ENST00000263317.9
NADPH oxidase 4
chr13_+_30617902 0.11 ENST00000255304.9
ENST00000614860.1
ubiquitin specific peptidase like 1
chr16_-_30526518 0.11 ENST00000380412.7
zinc finger protein 768
chr2_+_218568809 0.11 ENST00000273064.11
CCR4-NOT transcription complex subunit 9
chr19_-_35135011 0.10 ENST00000310123.8
leucine rich repeat LGI family member 4
chr6_-_33803980 0.10 ENST00000507738.1
ENST00000266003.9
ENST00000430124.7
motilin
chr2_-_74147868 0.10 ENST00000295326.4
ENST00000327428.10
bolA family member 3
chr2_+_218568558 0.09 ENST00000627282.2
ENST00000542068.5
CCR4-NOT transcription complex subunit 9
chr12_+_51912329 0.09 ENST00000547400.5
ENST00000550683.5
ENST00000419526.6
activin A receptor like type 1
chr14_+_104707253 0.09 ENST00000674602.1
inverted formin 2
chr19_-_10503186 0.08 ENST00000592055.2
ENST00000171111.10
kelch like ECH associated protein 1
chr17_-_45490696 0.08 ENST00000430334.8
ENST00000584420.1
ENST00000589780.5
pleckstrin homology and RUN domain containing M1
chr11_+_67483019 0.07 ENST00000279146.8
ENST00000528641.7
ENST00000682324.1
ENST00000684006.1
ENST00000683237.1
ENST00000684657.1
aryl hydrocarbon receptor interacting protein
chr9_-_89178810 0.07 ENST00000375835.9
SHC adaptor protein 3
chrX_-_153875847 0.06 ENST00000361699.8
ENST00000361981.7
L1 cell adhesion molecule
chr18_+_80109236 0.05 ENST00000262198.9
ENST00000560752.5
ADNP homeobox 2
chr4_-_170090153 0.05 ENST00000509167.5
ENST00000353187.6
ENST00000507375.5
ENST00000515480.5
aminoadipate aminotransferase
chr12_+_120438107 0.05 ENST00000229379.3
ENST00000551806.1
cytochrome c oxidase subunit 6A1
novel protein
chr17_+_43025203 0.05 ENST00000587250.4
Rho family GTPase 2
chr7_-_29990113 0.05 ENST00000426154.5
ENST00000421434.5
ENST00000434476.6
secernin 1
chr5_-_33891941 0.04 ENST00000352040.7
ENST00000504830.6
ADAM metallopeptidase with thrombospondin type 1 motif 12
chr17_+_75261661 0.04 ENST00000579761.5
mitochondrial ribosomal protein S7
chr11_-_47642519 0.04 ENST00000302503.8
ENST00000530428.1
mitochondrial carrier 2
chr5_+_139293939 0.04 ENST00000508689.1
ENST00000514528.5
matrin 3
chr1_+_103525690 0.04 ENST00000524631.5
ENST00000531883.5
ENST00000533099.5
ENST00000423855.7
ENST00000527062.5
RNA binding region (RNP1, RRM) containing 3
chr4_+_183506082 0.04 ENST00000412117.1
inhibitor of growth family member 2
chr17_+_35809474 0.03 ENST00000604879.5
ENST00000603427.5
ENST00000603777.5
ENST00000605844.6
ENST00000604841.5
TATA-box binding protein associated factor 15
chr1_+_25272527 0.02 ENST00000342055.9
ENST00000357542.8
ENST00000417538.6
ENST00000423810.6
ENST00000568195.5
Rh blood group D antigen
chr11_+_67483119 0.02 ENST00000682659.1
ENST00000525341.2
aryl hydrocarbon receptor interacting protein
chr1_+_32741779 0.02 ENST00000401073.7
KIAA1522
chr9_-_93453540 0.01 ENST00000375412.11
family with sequence similarity 120A opposite strand
chr17_-_1179940 0.01 ENST00000302538.10
ABR activator of RhoGEF and GTPase
chr1_+_25272439 0.00 ENST00000648012.1
Rh blood group D antigen
chr5_+_145936554 0.00 ENST00000359120.9
SH3 domain containing ring finger 2
chr2_-_84459232 0.00 ENST00000393868.7
succinate-CoA ligase GDP/ADP-forming subunit alpha

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 8.6 GO:0061709 reticulophagy(GO:0061709)
0.6 2.3 GO:0044805 late nucleophagy(GO:0044805)
0.5 1.9 GO:0090301 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.5 1.4 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.3 0.9 GO:0072248 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.3 6.0 GO:0036158 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.3 1.2 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.3 1.7 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.3 0.8 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 1.0 GO:0061760 antifungal innate immune response(GO:0061760)
0.2 3.2 GO:0038203 TORC2 signaling(GO:0038203)
0.2 0.8 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.2 1.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.2 3.0 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2 5.4 GO:0072189 ureter development(GO:0072189)
0.2 0.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.2 2.3 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2 0.8 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 1.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 1.2 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1 1.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.6 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.4 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.8 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.4 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 1.0 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 2.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.2 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 1.1 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.4 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.7 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 1.2 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.5 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 1.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.5 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.8 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.0 GO:0030167 proteoglycan catabolic process(GO:0030167)
0.0 0.4 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0097513 myosin II filament(GO:0097513)
0.3 0.9 GO:0031251 PAN complex(GO:0031251)
0.3 0.9 GO:0005745 m-AAA complex(GO:0005745)
0.2 0.8 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 6.0 GO:0034451 centriolar satellite(GO:0034451)
0.1 3.2 GO:0031932 TORC2 complex(GO:0031932)
0.1 8.6 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 2.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.0 GO:0000124 SAGA complex(GO:0000124)
0.1 2.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 1.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.7 GO:0035859 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.1 1.2 GO:0042627 chylomicron(GO:0042627)
0.0 1.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.9 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 1.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 0.8 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.8 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.7 GO:0070728 leucine binding(GO:0070728)
0.1 0.4 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 1.4 GO:0009881 photoreceptor activity(GO:0009881)
0.1 1.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.3 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 1.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 5.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 1.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.2 PID FGF PATHWAY FGF signaling pathway
0.0 0.4 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 2.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis