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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR1I2

Z-value: 0.66

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Transcription factors associated with NR1I2

Gene Symbol Gene ID Gene Info
ENSG00000144852.20 NR1I2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I2hg38_v1_chr3_+_119782094_119782114-0.125.2e-01Click!

Activity profile of NR1I2 motif

Sorted Z-values of NR1I2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_50968966 2.63 ENST00000376851.7
kallikrein related peptidase 6
chr1_-_205449924 2.47 ENST00000367154.5
LEM domain containing 1
chr2_-_31217511 1.39 ENST00000403897.4
calpain 14
chr20_+_3796288 1.35 ENST00000439880.6
ENST00000245960.10
cell division cycle 25B
chr19_+_2096960 1.33 ENST00000588003.5
IZUMO family member 4
chr10_+_93073873 1.26 ENST00000224356.5
cytochrome P450 family 26 subfamily A member 1
chr4_-_158173004 1.14 ENST00000585682.6
golgi associated kinase 1B
chr20_-_54173976 1.14 ENST00000216862.8
cytochrome P450 family 24 subfamily A member 1
chr2_+_30231524 1.05 ENST00000395323.9
ENST00000406087.5
ENST00000404397.5
LBH regulator of WNT signaling pathway
chr2_-_191847068 1.03 ENST00000304141.5
caveolae associated protein 2
chr15_+_39581068 0.99 ENST00000397591.2
ENST00000260356.6
thrombospondin 1
chr4_-_158173042 0.97 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr19_+_34994778 0.94 ENST00000599564.5
GRAM domain containing 1A
chr1_+_150549734 0.94 ENST00000674043.1
ENST00000674058.1
ADAMTS like 4
chrX_+_136197020 0.91 ENST00000370676.7
four and a half LIM domains 1
chr10_-_119536533 0.87 ENST00000392865.5
regulator of G protein signaling 10
chr19_+_2096873 0.87 ENST00000395307.6
ENST00000395301.8
ENST00000620263.4
IZUMO family member 4
chr16_+_46884675 0.85 ENST00000562132.5
ENST00000440783.2
glutamic--pyruvic transaminase 2
chrX_+_136197039 0.85 ENST00000370683.6
four and a half LIM domains 1
chr1_+_15756659 0.84 ENST00000375771.5
filamin binding LIM protein 1
chr12_-_121800558 0.84 ENST00000546227.5
ras homolog family member F, filopodia associated
chrX_+_136196750 0.83 ENST00000539015.5
four and a half LIM domains 1
chr1_-_148679734 0.82 ENST00000606877.2
ENST00000593495.3
NBPF member 14
notch 2 N-terminal like B
chr7_+_134891400 0.82 ENST00000393118.6
caldesmon 1
chr1_-_153549120 0.79 ENST00000368712.1
S100 calcium binding protein A3
chr1_+_120723939 0.76 ENST00000624419.2
ENST00000652763.1
ENST00000620612.5
notch 2 N-terminal like R (pseudogene)
NBPF member 26
chr21_-_5973383 0.74 ENST00000464664.3
novel histone H2B family protein
chr19_+_2096937 0.72 ENST00000395296.5
IZUMO family member 4
chrX_-_135098695 0.72 ENST00000433425.4
small integral membrane protein 10 like 2B
chr3_-_139539577 0.70 ENST00000619087.4
retinol binding protein 1
chr9_-_120876356 0.69 ENST00000456291.1
PHD finger protein 19
chr11_+_130448633 0.69 ENST00000299164.4
ADAM metallopeptidase with thrombospondin type 1 motif 15
chr14_-_58427134 0.69 ENST00000555930.6
translocase of inner mitochondrial membrane 9
chr3_+_155083889 0.68 ENST00000680282.1
membrane metalloendopeptidase
chr11_+_121102666 0.67 ENST00000264037.2
tectorin alpha
chr3_+_155083523 0.65 ENST00000680057.1
membrane metalloendopeptidase
chr8_-_61646807 0.65 ENST00000522919.5
aspartate beta-hydroxylase
chr1_-_146229000 0.62 ENST00000612520.2
ENST00000579793.6
ENST00000362074.7
NBPF member 10
notch 2 N-terminal like A
chr2_-_55296361 0.62 ENST00000647547.1
coiled-coil domain containing 88A
chr12_-_52192007 0.61 ENST00000394815.3
keratin 80
chr12_-_95116967 0.61 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr12_-_52191981 0.60 ENST00000313234.9
keratin 80
chr1_+_15152522 0.60 ENST00000428417.5
transmembrane protein 51
chrX_+_65667645 0.58 ENST00000360270.7
moesin
chr20_+_44715360 0.58 ENST00000190983.5
cellular communication network factor 5
chr1_-_153549238 0.57 ENST00000368713.8
S100 calcium binding protein A3
chr8_-_81112055 0.57 ENST00000220597.4
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
chr7_-_42152396 0.57 ENST00000642432.1
ENST00000647255.1
ENST00000677288.1
GLI family zinc finger 3
chr1_+_15152558 0.56 ENST00000376014.7
ENST00000451326.6
transmembrane protein 51
chr4_-_110198650 0.56 ENST00000394607.7
ELOVL fatty acid elongase 6
chr4_-_110198579 0.55 ENST00000302274.8
ELOVL fatty acid elongase 6
chr11_+_62880863 0.55 ENST00000680297.1
solute carrier family 3 member 2
chr11_+_62880885 0.55 ENST00000541372.1
ENST00000539458.1
ENST00000338663.12
ENST00000681232.1
ENST00000681657.1
solute carrier family 3 member 2
chr16_-_2720217 0.54 ENST00000302641.8
serine protease 27
chr18_+_31447732 0.54 ENST00000257189.5
desmoglein 3
chr21_+_42403856 0.54 ENST00000291535.11
ubiquitin associated and SH3 domain containing A
chr2_+_236569817 0.53 ENST00000272928.4
atypical chemokine receptor 3
chr11_+_118607579 0.51 ENST00000530708.4
pleckstrin homology like domain family B member 1
chr4_+_147732070 0.48 ENST00000336498.8
Rho GTPase activating protein 10
chr19_-_43204223 0.47 ENST00000599746.5
pregnancy specific beta-1-glycoprotein 4
chr1_+_74235377 0.47 ENST00000326637.8
TNNI3 interacting kinase
chr8_-_109974688 0.47 ENST00000297404.1
potassium voltage-gated channel modifier subfamily V member 1
chr7_-_42152444 0.47 ENST00000479210.1
GLI family zinc finger 3
chr12_-_95790755 0.47 ENST00000343702.9
ENST00000344911.8
netrin 4
chr11_+_62881686 0.47 ENST00000536981.6
ENST00000539891.6
solute carrier family 3 member 2
chr13_+_32031300 0.47 ENST00000642040.1
FRY microtubule binding protein
chr5_+_33936386 0.46 ENST00000330120.5
relaxin family peptide receptor 3
chr6_+_37929959 0.46 ENST00000373389.5
zinc finger AN1-type containing 3
chr15_-_89211803 0.46 ENST00000563254.1
retinaldehyde binding protein 1
chr19_-_6393205 0.45 ENST00000595047.5
general transcription factor IIF subunit 1
chr3_+_38165484 0.45 ENST00000446845.5
ENST00000311806.8
oxidative stress responsive kinase 1
chr3_+_12288838 0.45 ENST00000455517.6
ENST00000681982.1
peroxisome proliferator activated receptor gamma
chr16_+_67173935 0.44 ENST00000566871.5
nucleolar protein 3
chr1_+_196819731 0.44 ENST00000320493.10
ENST00000367424.4
complement factor H related 1
chr5_-_1801284 0.43 ENST00000505818.1
mitochondrial ribosomal protein L36
chr5_+_66828762 0.43 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
microtubule associated serine/threonine kinase family member 4
chr19_-_6393131 0.43 ENST00000394456.10
general transcription factor IIF subunit 1
chr10_-_24721866 0.43 ENST00000416305.1
ENST00000320481.10
Rho GTPase activating protein 21
chr6_+_106098933 0.43 ENST00000369089.3
PR/SET domain 1
chr11_+_118607598 0.43 ENST00000600882.6
ENST00000356063.9
pleckstrin homology like domain family B member 1
chr20_-_13990609 0.42 ENST00000284951.10
ENST00000378072.5
SEL1L2 adaptor subunit of ERAD E3 ligase
chr1_+_218346235 0.42 ENST00000366929.4
transforming growth factor beta 2
chr1_-_231421146 0.42 ENST00000667629.1
ENST00000670301.1
ENST00000658954.1
egl-9 family hypoxia inducible factor 1
chr19_-_45153852 0.42 ENST00000589776.1
NTPase KAP family P-loop domain containing 1
chr4_-_119322128 0.41 ENST00000274024.4
fatty acid binding protein 2
chr1_-_149842736 0.41 ENST00000369159.2
H2A clustered histone 18
chr7_-_76618300 0.41 ENST00000441393.1
POM121 and ZP3 fusion
chrX_+_50067576 0.41 ENST00000376108.7
chloride voltage-gated channel 5
chr12_-_7936177 0.41 ENST00000544291.1
ENST00000075120.12
solute carrier family 2 member 3
chr14_-_58427158 0.39 ENST00000555097.1
ENST00000556367.6
ENST00000555404.5
translocase of inner mitochondrial membrane 9
chr7_-_94656197 0.39 ENST00000643903.1
ENST00000644122.1
ENST00000447873.6
ENST00000644816.1
ENST00000644375.1
sarcoglycan epsilon
chr11_-_111912871 0.39 ENST00000528628.5
crystallin alpha B
chr7_-_94656160 0.38 ENST00000644609.1
ENST00000643272.1
ENST00000646137.1
ENST00000646098.1
ENST00000643193.1
ENST00000437425.7
ENST00000644551.1
ENST00000415788.3
sarcoglycan epsilon
chr3_+_25428233 0.38 ENST00000437042.6
ENST00000330688.9
retinoic acid receptor beta
chr17_+_40341388 0.37 ENST00000394086.7
retinoic acid receptor alpha
chr2_+_233718734 0.37 ENST00000373409.8
UDP glucuronosyltransferase family 1 member A4
chr12_-_89352487 0.37 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr5_-_128339191 0.37 ENST00000507835.5
fibrillin 2
chr3_+_12289061 0.37 ENST00000652522.1
ENST00000652431.1
ENST00000652098.1
ENST00000651735.1
ENST00000397026.7
peroxisome proliferator activated receptor gamma
chr1_-_29181809 0.36 ENST00000466448.4
ENST00000373795.7
serine and arginine rich splicing factor 4
chr7_+_112450451 0.36 ENST00000429071.5
ENST00000403825.8
ENST00000675268.1
interferon related developmental regulator 1
novel protein
chr10_-_101588126 0.36 ENST00000339310.7
ENST00000299206.8
ENST00000413344.5
ENST00000429502.1
ENST00000430045.1
ENST00000370172.5
ENST00000370162.8
ENST00000628479.2
DNA polymerase lambda
chr18_+_63775369 0.36 ENST00000540675.5
serpin family B member 7
chr16_+_67173971 0.36 ENST00000563258.1
ENST00000568146.1
nucleolar protein 3
chr6_+_42929127 0.36 ENST00000394142.7
canopy FGF signaling regulator 3
chr18_+_63775395 0.36 ENST00000398019.7
serpin family B member 7
chr3_+_8501846 0.35 ENST00000454244.4
LIM and cysteine rich domains 1
chr1_+_149390612 0.35 ENST00000650865.1
ENST00000652191.1
ENST00000621744.4
notch 2 N-terminal like C
novel protein, identical to neuroblastoma breakpoint family, member 19 NBPF19
chr5_-_181242236 0.35 ENST00000507756.5
receptor for activated C kinase 1
chr1_+_115029823 0.35 ENST00000256592.3
thyroid stimulating hormone subunit beta
chr13_-_113864062 0.34 ENST00000327773.7
growth arrest specific 6
chr10_-_75235917 0.34 ENST00000469299.1
ENST00000372538.8
catechol-O-methyltransferase domain containing 1
chr19_+_49043837 0.34 ENST00000301408.7
chorionic gonadotropin subunit beta 5
chr7_-_94655993 0.34 ENST00000647110.1
ENST00000647048.1
ENST00000643020.1
ENST00000644682.1
ENST00000646119.1
ENST00000646265.1
ENST00000645445.1
ENST00000647334.1
ENST00000645262.1
ENST00000428696.7
ENST00000647096.1
ENST00000642394.1
ENST00000645725.1
ENST00000647351.1
ENST00000646943.1
ENST00000648936.2
ENST00000642707.1
ENST00000645109.1
ENST00000646489.1
ENST00000642933.1
ENST00000643128.1
ENST00000445866.7
ENST00000645101.1
ENST00000644116.1
ENST00000642441.1
ENST00000646879.1
ENST00000647018.1
sarcoglycan epsilon
chr3_-_142029108 0.34 ENST00000497579.5
transcription factor Dp-2
chr14_-_58427114 0.34 ENST00000556007.6
translocase of inner mitochondrial membrane 9
chr21_+_42403874 0.33 ENST00000319294.11
ENST00000398367.1
ubiquitin associated and SH3 domain containing A
chr3_+_111911604 0.33 ENST00000495180.1
pleckstrin homology like domain family B member 2
chr16_+_83953232 0.33 ENST00000565123.5
ENST00000393306.6
oxidative stress induced growth inhibitor 1
chr6_+_26272923 0.33 ENST00000377733.4
H2B clustered histone 10
chr18_+_23992773 0.33 ENST00000304621.10
tetratricopeptide repeat domain 39C
chr22_+_20774092 0.32 ENST00000215727.10
serpin family D member 1
chr2_-_208190001 0.32 ENST00000451346.5
ENST00000341287.9
chromosome 2 open reading frame 80
chr22_-_38302990 0.32 ENST00000612795.2
ENST00000451964.5
casein kinase 1 epsilon
chr2_+_233712905 0.31 ENST00000373414.4
UDP glucuronosyltransferase family 1 member A5
chr13_+_32031706 0.31 ENST00000542859.6
FRY microtubule binding protein
chr6_+_31547560 0.31 ENST00000376148.9
ENST00000376145.8
NFKB inhibitor like 1
chr2_+_223051814 0.30 ENST00000281830.3
potassium voltage-gated channel subfamily E regulatory subunit 4
chr1_+_43358998 0.30 ENST00000372462.1
cell division cycle 20
chr1_+_196943738 0.30 ENST00000367415.8
ENST00000367421.5
ENST00000649283.1
ENST00000476712.6
ENST00000496448.6
ENST00000473386.1
ENST00000649960.1
complement factor H related 2
chr14_-_73027077 0.30 ENST00000553891.5
ENST00000556143.6
zinc finger FYVE-type containing 1
chr22_-_38097772 0.29 ENST00000332536.10
BAR/IMD domain containing adaptor protein 2 like 2
chr1_+_43358968 0.29 ENST00000310955.11
cell division cycle 20
chr11_-_111923722 0.29 ENST00000527950.5
crystallin alpha B
chr14_+_76826372 0.29 ENST00000393774.7
ENST00000555189.1
leucine rich repeat containing 74A
chr19_-_51723968 0.29 ENST00000222115.5
ENST00000540069.7
hyaluronan synthase 1
chr1_+_11736068 0.29 ENST00000376637.7
angiotensin II receptor associated protein
chr1_+_11736120 0.28 ENST00000400895.6
ENST00000314340.10
ENST00000376629.8
ENST00000376627.6
ENST00000452018.6
ENST00000510878.1
angiotensin II receptor associated protein
chr16_-_1884231 0.28 ENST00000563416.3
ENST00000633813.1
ENST00000470044.5
long intergenic non-protein coding RNA 254
meiosis specific with OB-fold
chr15_-_64381431 0.28 ENST00000558008.3
ENST00000300035.9
ENST00000559519.5
ENST00000380258.6
PCNA clamp associated factor
chr13_-_32538683 0.28 ENST00000674456.1
ENST00000504114.5
NEDD4 binding protein 2 like 2
chr1_-_39883434 0.28 ENST00000541099.5
ENST00000441669.6
ENST00000316891.10
ENST00000537440.5
ENST00000372818.5
tRNA isopentenyltransferase 1
chr19_+_42313298 0.28 ENST00000301204.8
ENST00000673205.1
transmembrane protein 145
chr14_-_73027117 0.28 ENST00000318876.9
zinc finger FYVE-type containing 1
chr7_-_32892015 0.28 ENST00000452926.1
kelch repeat and BTB domain containing 2
chr17_-_48604959 0.28 ENST00000225648.4
ENST00000484302.3
homeobox B6
chr8_+_144095054 0.27 ENST00000318911.5
cytochrome c1
chrX_+_100584928 0.27 ENST00000373031.5
tenomodulin
chr4_+_5711154 0.27 ENST00000264956.11
ENST00000509451.1
EvC ciliary complex subunit 1
chr1_+_27934980 0.27 ENST00000373894.8
sphingomyelin phosphodiesterase acid like 3B
chr1_-_197067234 0.27 ENST00000367412.2
coagulation factor XIII B chain
chr14_-_102509798 0.27 ENST00000560748.5
ankyrin repeat domain 9
chr16_+_71358713 0.26 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
calbindin 2
chr1_-_248645278 0.26 ENST00000641268.1
olfactory receptor family 2 subfamily T member 35
chr1_-_12848720 0.26 ENST00000317869.7
heterogeneous nuclear ribonucleoprotein C like 1
chr17_-_7263959 0.26 ENST00000571932.2
claudin 7
chr19_+_39125769 0.26 ENST00000602004.1
ENST00000599470.5
ENST00000321944.8
ENST00000593480.5
ENST00000358301.7
ENST00000593690.5
ENST00000599386.5
p21 (RAC1) activated kinase 4
chr5_+_150190035 0.26 ENST00000230671.7
ENST00000524041.1
solute carrier family 6 member 7
chr5_+_137867852 0.26 ENST00000421631.6
ENST00000239926.9
myotilin
chr5_+_40679907 0.25 ENST00000302472.4
prostaglandin E receptor 4
chr10_-_100185993 0.25 ENST00000421367.7
ENST00000370408.2
ENST00000407654.7
ER lipid raft associated 1
chr5_-_113294895 0.25 ENST00000514701.5
ENST00000302475.8
MCC regulator of WNT signaling pathway
chr4_+_70734419 0.25 ENST00000502653.5
RUN and FYVE domain containing 3
chr3_+_8501807 0.25 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LIM and cysteine rich domains 1
chr14_+_94026314 0.25 ENST00000203664.10
ENST00000553723.1
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr20_-_34112205 0.25 ENST00000374980.3
eukaryotic translation initiation factor 2 subunit beta
chr17_-_8162932 0.25 ENST00000488857.5
ENST00000316509.11
ENST00000481878.1
ENST00000498285.1
vesicle associated membrane protein 2
novel protein
chr1_+_42825548 0.25 ENST00000372514.7
erythroblast membrane associated protein (Scianna blood group)
chr9_-_118417 0.25 ENST00000382500.4
forkhead box D4
chr4_+_123396785 0.24 ENST00000505319.5
ENST00000651917.1
ENST00000610581.4
ENST00000339241.1
sprouty RTK signaling antagonist 1
chr2_-_208129824 0.24 ENST00000282141.4
crystallin gamma C
chr5_+_145937793 0.24 ENST00000511217.1
SH3 domain containing ring finger 2
chr7_+_92245960 0.24 ENST00000265742.8
ankyrin repeat and IBR domain containing 1
chr17_-_35121487 0.24 ENST00000593039.5
RAD51L3-RFFL readthrough
chr22_+_24607602 0.24 ENST00000447416.5
gamma-glutamyltransferase 1
chr2_+_167248638 0.23 ENST00000295237.10
xin actin binding repeat containing 2
chr17_-_43546323 0.23 ENST00000545954.5
ENST00000319349.10
ETS variant transcription factor 4
chr1_-_146021724 0.23 ENST00000475797.1
ENST00000497365.5
ENST00000336751.11
ENST00000634927.1
ENST00000421822.2
hemojuvelin BMP co-receptor
chr6_+_1609890 0.23 ENST00000645831.2
forkhead box C1
chr6_+_27815010 0.23 ENST00000621112.2
H2B clustered histone 14
chr12_-_27014300 0.23 ENST00000535819.1
ENST00000543803.5
ENST00000535423.5
ENST00000539741.5
ENST00000343028.9
ENST00000545600.1
ENST00000543088.5
transmembrane 7 superfamily member 3
chr11_+_67023085 0.23 ENST00000527043.6
synaptotagmin 12
chr11_+_307915 0.22 ENST00000616316.2
interferon induced transmembrane protein 2
chr1_+_151766655 0.22 ENST00000400999.7
ornithine decarboxylase antizyme 3
chr13_-_33285682 0.22 ENST00000336934.10
StAR related lipid transfer domain containing 13
chr14_+_35122537 0.22 ENST00000604948.5
ENST00000321130.14
ENST00000534898.9
ENST00000605201.1
ENST00000250377.11
protein only RNase P catalytic subunit
chr7_+_111091006 0.22 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr6_-_27814757 0.22 ENST00000333151.5
H2A clustered histone 14
chr9_-_93453540 0.22 ENST00000375412.11
family with sequence similarity 120A opposite strand
chr11_-_111913134 0.22 ENST00000533971.2
ENST00000526180.6
crystallin alpha B
chr2_-_25341886 0.22 ENST00000321117.10
DNA methyltransferase 3 alpha
chr16_-_4242068 0.21 ENST00000399609.7
sarcalumenin
chr1_+_149886906 0.21 ENST00000331380.4
H2A clustered histone 20
chr7_+_111091119 0.21 ENST00000308478.10
leucine rich repeat neuronal 3
chr19_+_42313374 0.21 ENST00000598766.1
ENST00000673187.1
transmembrane protein 145
chr6_+_159169391 0.21 ENST00000297267.14
fibronectin type III domain containing 1
chr19_+_4153616 0.21 ENST00000078445.7
ENST00000595923.5
ENST00000602257.5
ENST00000602147.1
cAMP responsive element binding protein 3 like 3
chr11_-_111913195 0.21 ENST00000531198.5
ENST00000616970.5
ENST00000527899.6
crystallin alpha B
chr1_+_6034980 0.21 ENST00000378092.6
ENST00000472700.7
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr2_+_170178136 0.21 ENST00000409044.7
ENST00000408978.9
myosin IIIB

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.4 1.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.3 1.0 GO:0060367 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.3 1.1 GO:0042369 vitamin D catabolic process(GO:0042369)
0.3 0.8 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.3 1.6 GO:0060356 leucine import(GO:0060356)
0.2 1.0 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.2 0.8 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.2 0.9 GO:0042853 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.2 0.7 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 1.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.4 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.1 0.7 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 2.6 GO:0016540 protein autoprocessing(GO:0016540)
0.1 1.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.4 GO:0007518 myoblast fate determination(GO:0007518)
0.1 1.6 GO:0007144 female meiosis I(GO:0007144)
0.1 0.8 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.3 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.1 0.5 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.3 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.4 GO:0030821 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.1 0.6 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 1.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.6 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.4 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.3 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.3 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.2 GO:0015847 putrescine transport(GO:0015847)
0.1 0.3 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.5 GO:0019236 response to pheromone(GO:0019236)
0.1 0.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.7 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.2 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 1.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.4 GO:0035803 egg coat formation(GO:0035803)
0.1 0.2 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 1.3 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.7 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 1.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.2 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.7 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.9 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.3 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.3 GO:0008218 bioluminescence(GO:0008218)
0.1 0.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.2 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.1 0.2 GO:0051695 actin filament uncapping(GO:0051695)
0.1 0.6 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.0 0.4 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.4 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.2 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.3 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.6 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.7 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 1.0 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.4 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 2.6 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.2 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 0.4 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0043397 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.4 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.3 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.1 GO:0072004 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney field specification(GO:0072004) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.2 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.1 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.3 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.0 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.0 GO:0035498 carnosine metabolic process(GO:0035498)
0.0 0.6 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.4 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 1.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.6 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.2 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.1 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:1990879 CST complex(GO:1990879)
0.0 0.4 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.0 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.0 GO:0097546 mediator complex(GO:0016592) ciliary base(GO:0097546)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 1.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 2.4 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 1.0 GO:0070052 collagen V binding(GO:0070052)
0.3 0.9 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.2 0.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 0.8 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.3 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.1 1.1 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.9 GO:0089720 caspase binding(GO:0089720)
0.1 0.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.6 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.2 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.1 0.8 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.9 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.5 GO:0043237 laminin-1 binding(GO:0043237)
0.0 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0031013 troponin I binding(GO:0031013)
0.0 2.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.7 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0031005 filamin binding(GO:0031005)
0.0 0.6 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0005334 norepinephrine:sodium symporter activity(GO:0005334)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 3.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0008171 O-methyltransferase activity(GO:0008171)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.7 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.9 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha