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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR2E1

Z-value: 0.76

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Transcription factors associated with NR2E1

Gene Symbol Gene ID Gene Info
NR2E1
ENSG00000112333.12 NR2E1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2E1hg38_v1_chr6_+_108166015_1081660340.261.7e-01Click!

Activity profile of NR2E1 motif

Sorted Z-values of NR2E1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_31414694 2.70 ENST00000379416.4
XDH
xanthine dehydrogenase
chr1_-_205449924 2.42 ENST00000367154.5
LEMD1
LEM domain containing 1
chr5_-_73448769 2.25 ENST00000615637.3
FOXD1
forkhead box D1
chr1_+_31576485 1.98 ENST00000457433.6
ENST00000271064.12
TINAGL1
tubulointerstitial nephritis antigen like 1
chr4_-_110198579 1.66 ENST00000302274.8
ELOVL6
ELOVL fatty acid elongase 6
chr4_-_110198650 1.64 ENST00000394607.7
ELOVL6
ELOVL fatty acid elongase 6
chr2_+_113127588 1.61 ENST00000409930.4
IL1RN
interleukin 1 receptor antagonist
chr18_+_31447732 1.61 ENST00000257189.5
DSG3
desmoglein 3
chr11_-_63671909 1.53 ENST00000538786.1
ENST00000540699.1
ATL3
atlastin GTPase 3
chr11_-_62556230 1.47 ENST00000530285.5
AHNAK
AHNAK nucleoprotein
chr4_-_47981535 1.46 ENST00000402813.9
CNGA1
cyclic nucleotide gated channel subunit alpha 1
chr12_-_89352487 1.42 ENST00000548755.1
ENST00000279488.8
DUSP6
dual specificity phosphatase 6
chr5_-_11588842 1.28 ENST00000503622.5
CTNND2
catenin delta 2
chr10_+_11742361 1.27 ENST00000379215.9
ENST00000420401.5
ECHDC3
enoyl-CoA hydratase domain containing 3
chr5_-_11589019 1.24 ENST00000511377.5
CTNND2
catenin delta 2
chr7_+_116526277 1.19 ENST00000393468.1
ENST00000393467.1
CAV1
caveolin 1
chr3_+_122055355 1.16 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86
CD86 molecule
chrX_-_66040107 1.13 ENST00000455586.6
VSIG4
V-set and immunoglobulin domain containing 4
chr11_+_35176696 1.11 ENST00000528455.5
CD44
CD44 molecule (Indian blood group)
chr12_-_119803383 1.11 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
CIT
citron rho-interacting serine/threonine kinase
chrX_-_66040072 1.10 ENST00000374737.9
VSIG4
V-set and immunoglobulin domain containing 4
chrX_-_66040057 1.08 ENST00000412866.2
VSIG4
V-set and immunoglobulin domain containing 4
chrX_-_66033664 1.07 ENST00000427538.5
VSIG4
V-set and immunoglobulin domain containing 4
chr17_-_43546323 1.04 ENST00000545954.5
ENST00000319349.10
ETV4
ETS variant transcription factor 4
chr22_-_30299482 1.00 ENST00000434291.5
ENSG00000248751.6
novel protein
chr6_+_12290353 0.99 ENST00000379375.6
EDN1
endothelin 1
chr11_+_35176575 0.98 ENST00000526000.6
CD44
CD44 molecule (Indian blood group)
chr12_+_56521951 0.98 ENST00000552247.6
RBMS2
RNA binding motif single stranded interacting protein 2
chr7_-_107803215 0.97 ENST00000340010.10
ENST00000453332.1
SLC26A3
solute carrier family 26 member 3
chr12_+_56521990 0.96 ENST00000550726.5
ENST00000542360.1
RBMS2
RNA binding motif single stranded interacting protein 2
chrX_+_47585212 0.96 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr11_+_35176639 0.95 ENST00000527889.6
CD44
CD44 molecule (Indian blood group)
chr14_+_22508602 0.95 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr11_+_35176611 0.92 ENST00000279452.10
CD44
CD44 molecule (Indian blood group)
chrX_+_136532205 0.91 ENST00000370634.8
VGLL1
vestigial like family member 1
chr4_+_70197924 0.89 ENST00000514097.5
ODAM
odontogenic, ameloblast associated
chr12_-_27971970 0.86 ENST00000395872.5
ENST00000201015.8
PTHLH
parathyroid hormone like hormone
chr1_-_162412117 0.85 ENST00000367929.3
SH2D1B
SH2 domain containing 1B
chr8_-_17002327 0.83 ENST00000180166.6
FGF20
fibroblast growth factor 20
chr9_-_96302104 0.82 ENST00000375262.4
ENST00000650386.1
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr2_-_89143133 0.79 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr17_+_2056073 0.78 ENST00000576444.1
ENST00000322941.3
HIC1
HIC ZBTB transcriptional repressor 1
chr12_-_94650506 0.77 ENST00000261226.9
TMCC3
transmembrane and coiled-coil domain family 3
chr2_-_207165923 0.76 ENST00000309446.11
KLF7
Kruppel like factor 7
chr17_+_17179527 0.76 ENST00000579361.1
MPRIP
myosin phosphatase Rho interacting protein
chr6_+_106098933 0.74 ENST00000369089.3
PRDM1
PR/SET domain 1
chr12_-_81758665 0.74 ENST00000549325.5
ENST00000550584.6
PPFIA2
PTPRF interacting protein alpha 2
chr4_-_4542034 0.73 ENST00000306200.7
STX18
syntaxin 18
chr11_-_111923722 0.73 ENST00000527950.5
CRYAB
crystallin alpha B
chr9_-_21994345 0.69 ENST00000579755.2
ENST00000530628.2
CDKN2A
cyclin dependent kinase inhibitor 2A
chr1_-_197067234 0.68 ENST00000367412.2
F13B
coagulation factor XIII B chain
chr14_+_66824439 0.68 ENST00000555456.1
GPHN
gephyrin
chr3_+_136957948 0.67 ENST00000329582.9
IL20RB
interleukin 20 receptor subunit beta
chr2_+_28395511 0.64 ENST00000436647.1
FOSL2
FOS like 2, AP-1 transcription factor subunit
chr9_-_96302142 0.63 ENST00000648799.1
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr12_-_91178520 0.62 ENST00000425043.5
ENST00000420120.6
ENST00000441303.6
ENST00000456569.2
DCN
decorin
chr12_+_53268289 0.62 ENST00000257934.9
ESPL1
extra spindle pole bodies like 1, separase
chr2_-_213150236 0.61 ENST00000442445.1
ENST00000342002.6
IKZF2
IKAROS family zinc finger 2
chr2_+_114442616 0.61 ENST00000410059.6
DPP10
dipeptidyl peptidase like 10
chrX_-_49184789 0.61 ENST00000453382.5
ENST00000432913.5
PRICKLE3
prickle planar cell polarity protein 3
chr11_-_128587551 0.60 ENST00000392668.8
ETS1
ETS proto-oncogene 1, transcription factor
chr11_-_31812171 0.60 ENST00000639409.1
ENST00000640975.1
PAX6
paired box 6
chr3_+_128052390 0.59 ENST00000481210.5
ENST00000243253.8
SEC61A1
SEC61 translocon subunit alpha 1
chr2_+_191276885 0.59 ENST00000392316.5
MYO1B
myosin IB
chr1_+_165895564 0.59 ENST00000469256.6
UCK2
uridine-cytidine kinase 2
chr2_+_11539833 0.58 ENST00000263834.9
GREB1
growth regulating estrogen receptor binding 1
chr5_-_140633690 0.57 ENST00000512545.1
ENST00000401743.6
CD14
CD14 molecule
chr3_+_141387616 0.56 ENST00000509883.5
ZBTB38
zinc finger and BTB domain containing 38
chr1_+_39955112 0.56 ENST00000420632.6
ENST00000372811.10
ENST00000434861.5
ENST00000372809.5
MFSD2A
major facilitator superfamily domain containing 2A
chr12_-_52493250 0.56 ENST00000330722.7
KRT6A
keratin 6A
chr8_+_11809135 0.55 ENST00000528643.5
ENST00000525777.5
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr1_-_243850216 0.55 ENST00000673466.1
AKT3
AKT serine/threonine kinase 3
chr9_-_96302170 0.55 ENST00000375263.8
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr1_-_154183199 0.55 ENST00000323144.12
ENST00000330188.13
ENST00000328159.9
ENST00000611659.4
TPM3
tropomyosin 3
chr2_+_90038848 0.54 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr5_-_179620933 0.53 ENST00000521173.5
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1
chr3_-_116444983 0.53 ENST00000333617.8
LSAMP
limbic system associated membrane protein
chr3_+_189631373 0.52 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
TP63
tumor protein p63
chr1_-_99766620 0.51 ENST00000646001.2
FRRS1
ferric chelate reductase 1
chr6_-_87702221 0.51 ENST00000257787.6
AKIRIN2
akirin 2
chr3_-_33645433 0.50 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
CLASP2
cytoplasmic linker associated protein 2
chrX_+_116170742 0.50 ENST00000371906.5
ENST00000681852.1
AGTR2
angiotensin II receptor type 2
chr10_-_68407242 0.50 ENST00000399200.7
ENST00000602465.6
ENST00000454950.6
RUFY2
RUN and FYVE domain containing 2
chr2_-_55296361 0.50 ENST00000647547.1
CCDC88A
coiled-coil domain containing 88A
chr20_+_1895365 0.49 ENST00000358771.5
SIRPA
signal regulatory protein alpha
chr7_+_116672357 0.49 ENST00000456159.1
MET
MET proto-oncogene, receptor tyrosine kinase
chr4_-_142846275 0.49 ENST00000513000.5
ENST00000509777.5
ENST00000503927.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr1_+_213989691 0.48 ENST00000607425.1
PROX1
prospero homeobox 1
chr19_+_11435619 0.47 ENST00000589126.5
ENST00000588269.1
ENST00000587509.5
ENST00000591462.6
ENST00000592741.5
ENST00000677123.1
ENST00000593101.5
ENST00000587327.5
PRKCSH
protein kinase C substrate 80K-H
chr16_+_3018390 0.46 ENST00000573001.5
TNFRSF12A
TNF receptor superfamily member 12A
chr2_+_230759918 0.45 ENST00000614925.1
CAB39
calcium binding protein 39
chr3_-_197183806 0.45 ENST00000671246.1
ENST00000660553.1
DLG1
discs large MAGUK scaffold protein 1
chr4_-_156970903 0.44 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr3_+_12351493 0.44 ENST00000683699.1
PPARG
peroxisome proliferator activated receptor gamma
chr17_+_67377272 0.43 ENST00000581322.6
ENST00000299954.13
PITPNC1
phosphatidylinositol transfer protein cytoplasmic 1
chr3_-_185821092 0.43 ENST00000421047.3
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr19_-_14848922 0.43 ENST00000641129.1
OR7A10
olfactory receptor family 7 subfamily A member 10
chrX_-_54798253 0.43 ENST00000218436.7
ITIH6
inter-alpha-trypsin inhibitor heavy chain family member 6
chr3_+_12351470 0.42 ENST00000287820.10
PPARG
peroxisome proliferator activated receptor gamma
chrX_+_47218670 0.42 ENST00000357227.9
ENST00000519758.5
ENST00000520893.5
ENST00000622098.4
ENST00000517426.5
CDK16
cyclin dependent kinase 16
chr10_-_68407189 0.42 ENST00000388768.6
RUFY2
RUN and FYVE domain containing 2
chr2_-_157444044 0.42 ENST00000264192.8
CYTIP
cytohesin 1 interacting protein
chr6_+_42564060 0.42 ENST00000372903.6
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr4_+_95091462 0.41 ENST00000264568.8
BMPR1B
bone morphogenetic protein receptor type 1B
chr11_-_31807617 0.40 ENST00000639920.1
ENST00000640460.1
PAX6
paired box 6
chr1_-_154183130 0.40 ENST00000368531.6
ENST00000368533.8
TPM3
tropomyosin 3
chr6_-_32151899 0.40 ENST00000211413.10
PRRT1
proline rich transmembrane protein 1
chr15_-_56245074 0.39 ENST00000674082.1
RFX7
regulatory factor X7
chr10_+_122560751 0.38 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
DMBT1
deleted in malignant brain tumors 1
chr17_+_37375974 0.38 ENST00000615133.2
ENST00000611038.4
C17orf78
chromosome 17 open reading frame 78
chr3_+_101827982 0.38 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKBIZ
NFKB inhibitor zeta
chr1_+_76867469 0.38 ENST00000477717.6
ST6GALNAC5
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr5_-_88883199 0.38 ENST00000514015.5
ENST00000503075.1
MEF2C
myocyte enhancer factor 2C
chr9_-_92482350 0.38 ENST00000375543.2
ASPN
asporin
chrX_-_31178220 0.38 ENST00000681026.1
DMD
dystrophin
chr6_+_125219804 0.38 ENST00000524679.1
TPD52L1
TPD52 like 1
chr17_-_42681840 0.37 ENST00000332438.4
CCR10
C-C motif chemokine receptor 10
chr5_-_83673544 0.37 ENST00000503117.1
ENST00000510978.5
HAPLN1
hyaluronan and proteoglycan link protein 1
chr1_+_115029823 0.37 ENST00000256592.3
TSHB
thyroid stimulating hormone subunit beta
chr7_-_13986439 0.37 ENST00000443608.5
ENST00000438956.5
ETV1
ETS variant transcription factor 1
chr1_+_50109817 0.36 ENST00000652353.1
ENST00000371821.6
ENST00000652274.1
ELAVL4
ELAV like RNA binding protein 4
chrX_-_53684119 0.36 ENST00000342160.7
ENST00000446750.1
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
chr10_+_122560679 0.36 ENST00000657942.1
DMBT1
deleted in malignant brain tumors 1
chr12_-_7936177 0.36 ENST00000544291.1
ENST00000075120.12
SLC2A3
solute carrier family 2 member 3
chrX_-_31178149 0.35 ENST00000679437.1
DMD
dystrophin
chr14_-_56810448 0.35 ENST00000339475.10
ENST00000555006.5
ENST00000672264.2
ENST00000554559.5
ENST00000555804.1
OTX2
orthodenticle homeobox 2
chr8_-_92017292 0.35 ENST00000521553.5
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr16_+_21678514 0.35 ENST00000286149.8
ENST00000388958.8
OTOA
otoancorin
chr12_-_10172117 0.35 ENST00000545927.5
ENST00000309539.8
ENST00000432556.6
ENST00000544577.5
OLR1
oxidized low density lipoprotein receptor 1
chr5_-_113434978 0.34 ENST00000390666.4
TSSK1B
testis specific serine kinase 1B
chr15_+_67067780 0.34 ENST00000679624.1
SMAD3
SMAD family member 3
chrX_+_47218232 0.34 ENST00000457458.6
ENST00000522883.1
CDK16
cyclin dependent kinase 16
chr12_-_99154867 0.34 ENST00000549025.6
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr18_+_24460630 0.34 ENST00000256906.5
HRH4
histamine receptor H4
chr10_+_122560639 0.34 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
DMBT1
deleted in malignant brain tumors 1
chr8_+_11704151 0.33 ENST00000526716.5
ENST00000532059.6
ENST00000335135.8
ENST00000622443.3
GATA4
GATA binding protein 4
chr12_+_14365729 0.33 ENST00000536444.5
ATF7IP
activating transcription factor 7 interacting protein
chr19_-_633500 0.33 ENST00000588649.7
POLRMT
RNA polymerase mitochondrial
chr18_+_24460655 0.33 ENST00000426880.2
HRH4
histamine receptor H4
chrX_-_33128360 0.33 ENST00000378677.6
DMD
dystrophin
chr1_-_154178174 0.33 ENST00000302206.9
TPM3
tropomyosin 3
chr6_-_130222813 0.33 ENST00000437477.6
ENST00000439090.7
SAMD3
sterile alpha motif domain containing 3
chr2_-_208146150 0.33 ENST00000260988.5
CRYGB
crystallin gamma B
chr9_+_96928843 0.33 ENST00000372322.4
NUTM2G
NUT family member 2G
chr19_-_46717076 0.33 ENST00000601806.5
ENST00000593363.1
ENST00000291281.9
ENST00000598633.1
ENST00000595515.5
ENST00000433867.5
PRKD2
protein kinase D2
chr5_-_151157722 0.32 ENST00000517486.5
ENST00000377751.9
ENST00000521512.5
ENST00000517757.5
ENST00000354546.10
ANXA6
annexin A6
chr6_-_155455830 0.32 ENST00000159060.3
NOX3
NADPH oxidase 3
chr16_-_20697680 0.32 ENST00000520010.6
ACSM1
acyl-CoA synthetase medium chain family member 1
chr4_+_80266639 0.31 ENST00000456523.3
ENST00000312465.12
FGF5
fibroblast growth factor 5
chr3_-_112133218 0.31 ENST00000488580.5
ENST00000308910.9
ENST00000460387.6
ENST00000484193.5
ENST00000487901.1
GCSAM
germinal center associated signaling and motility
chr16_-_69754913 0.30 ENST00000268802.10
NOB1
NIN1 (RPN12) binding protein 1 homolog
chr8_-_123396412 0.30 ENST00000287394.10
ATAD2
ATPase family AAA domain containing 2
chr4_-_152382522 0.30 ENST00000296555.11
FBXW7
F-box and WD repeat domain containing 7
chr12_-_91153149 0.30 ENST00000550758.1
DCN
decorin
chr12_+_14365661 0.30 ENST00000261168.9
ENST00000538511.5
ENST00000545723.1
ENST00000543189.5
ATF7IP
activating transcription factor 7 interacting protein
chr1_-_243843164 0.30 ENST00000491219.6
ENST00000680056.1
ENST00000492957.2
AKT3
AKT serine/threonine kinase 3
chr14_+_51489112 0.30 ENST00000356218.8
FRMD6
FERM domain containing 6
chr19_-_46654657 0.29 ENST00000300875.4
DACT3
dishevelled binding antagonist of beta catenin 3
chr3_-_114178698 0.29 ENST00000467632.5
DRD3
dopamine receptor D3
chr17_-_676348 0.29 ENST00000681510.1
ENST00000679680.1
VPS53
VPS53 subunit of GARP complex
chr6_+_54307856 0.29 ENST00000370869.7
TINAG
tubulointerstitial nephritis antigen
chr3_-_58211212 0.28 ENST00000461914.7
DNASE1L3
deoxyribonuclease 1 like 3
chr3_-_132037800 0.28 ENST00000617767.4
CPNE4
copine 4
chr9_-_94328644 0.28 ENST00000341207.5
ENST00000253262.9
NUTM2F
NUT family member 2F
chr1_-_20508095 0.28 ENST00000264198.5
MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr7_+_16526824 0.27 ENST00000401542.3
LRRC72
leucine rich repeat containing 72
chr5_-_16936231 0.27 ENST00000507288.1
ENST00000274203.13
ENST00000513610.6
MYO10
myosin X
chr20_+_43945677 0.27 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr1_+_62597510 0.27 ENST00000371129.4
ANGPTL3
angiopoietin like 3
chr1_-_115768702 0.27 ENST00000261448.6
CASQ2
calsequestrin 2
chr1_+_67685342 0.27 ENST00000617962.2
GADD45A
growth arrest and DNA damage inducible alpha
chr10_-_68232108 0.27 ENST00000373673.5
ATOH7
atonal bHLH transcription factor 7
chr5_+_32711723 0.27 ENST00000415167.2
NPR3
natriuretic peptide receptor 3
chr4_+_88592426 0.27 ENST00000431413.5
ENST00000402738.6
ENST00000422770.5
ENST00000407637.5
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr9_-_92482499 0.27 ENST00000375544.7
ASPN
asporin
chr7_-_106285898 0.26 ENST00000424768.2
ENST00000681255.1
NAMPT
nicotinamide phosphoribosyltransferase
chr7_+_107168961 0.26 ENST00000468410.5
ENST00000478930.5
ENST00000464009.1
ENST00000222574.9
HBP1
HMG-box transcription factor 1
chr18_+_44680093 0.26 ENST00000426838.8
ENST00000677068.1
SETBP1
SET binding protein 1
chr11_-_111910790 0.26 ENST00000533280.6
CRYAB
crystallin alpha B
chr7_-_108240049 0.25 ENST00000379022.8
NRCAM
neuronal cell adhesion molecule
chr10_+_84230660 0.25 ENST00000652073.1
RGR
retinal G protein coupled receptor
chr16_+_7304219 0.25 ENST00000675562.1
RBFOX1
RNA binding fox-1 homolog 1
chr1_+_50105666 0.25 ENST00000651347.1
ELAVL4
ELAV like RNA binding protein 4
chr20_+_64164474 0.25 ENST00000622439.4
ENST00000536311.5
MYT1
myelin transcription factor 1
chr1_-_155978144 0.24 ENST00000313695.11
ENST00000497907.5
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2
chr20_+_64164446 0.24 ENST00000328439.6
MYT1
myelin transcription factor 1
chr16_-_58546702 0.24 ENST00000567133.1
CNOT1
CCR4-NOT transcription complex subunit 1
chr11_-_111910830 0.24 ENST00000526167.5
ENST00000651650.1
CRYAB
crystallin alpha B
chr2_-_55010348 0.24 ENST00000394609.6
RTN4
reticulon 4
chr7_-_42152396 0.24 ENST00000642432.1
ENST00000647255.1
ENST00000677288.1
GLI3
GLI family zinc finger 3
chr10_-_24721866 0.24 ENST00000416305.1
ENST00000320481.10
ARHGAP21
Rho GTPase activating protein 21
chr7_-_42152444 0.23 ENST00000479210.1
GLI3
GLI family zinc finger 3
chr20_+_64164566 0.23 ENST00000650655.1
MYT1
myelin transcription factor 1
chr14_+_61697622 0.23 ENST00000539097.2
HIF1A
hypoxia inducible factor 1 subunit alpha
chr10_-_21174187 0.23 ENST00000417816.2
NEBL
nebulette
chr16_-_3018170 0.22 ENST00000572154.1
ENST00000328796.5
CLDN6
claudin 6
chr9_-_16727980 0.22 ENST00000418777.5
ENST00000468187.6
BNC2
basonuclin 2
chr3_-_50322759 0.22 ENST00000442581.1
ENST00000447092.5
HYAL2
hyaluronidase 2
chr11_-_13496018 0.22 ENST00000529816.1
PTH
parathyroid hormone
chr19_-_45730861 0.22 ENST00000317683.4
FBXO46
F-box protein 46

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0046110 xanthine metabolic process(GO:0046110)
0.4 2.2 GO:0072076 nephrogenic mesenchyme development(GO:0072076) pattern specification involved in metanephros development(GO:0072268)
0.4 1.2 GO:0002668 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.3 1.0 GO:0030185 nitric oxide transport(GO:0030185)
0.3 3.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 1.2 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.3 3.9 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3 1.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.7 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.2 0.7 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 0.7 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.2 4.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.6 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 2.0 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.2 0.6 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.2 0.7 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.2 0.5 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) negative regulation of icosanoid secretion(GO:0032304)
0.2 0.5 GO:2000979 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.2 0.5 GO:0060873 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.1 0.6 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.4 GO:0070295 renal water absorption(GO:0070295)
0.1 0.5 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.6 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.9 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.6 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.6 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.5 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.6 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.3 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.6 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.9 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 1.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.6 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.8 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 0.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.3 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.3 GO:0003290 atrial septum secundum morphogenesis(GO:0003290) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.1 0.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 1.1 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.1 0.3 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 1.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.3 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 1.0 GO:0019532 oxalate transport(GO:0019532)
0.1 0.3 GO:0003383 apical constriction(GO:0003383)
0.1 0.3 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.4 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 1.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.2 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.2 GO:2000642 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.4 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 1.0 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.1 GO:0060129 mesodermal cell migration(GO:0008078) corticotropin hormone secreting cell differentiation(GO:0060128) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.2 GO:0021502 neural fold elevation formation(GO:0021502)
0.1 0.3 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.6 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 0.6 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0 0.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.4 GO:0060125 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.0 0.3 GO:0048840 otolith development(GO:0048840)
0.0 1.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0016119 carotene metabolic process(GO:0016119)
0.0 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.5 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.4 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.8 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.4 GO:1903764 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.3 GO:0051005 negative regulation of phospholipase activity(GO:0010519) negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.8 GO:0002076 osteoblast development(GO:0002076)
0.0 0.3 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.8 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.8 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.6 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.6 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717)
0.0 1.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.3 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.3 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.0 1.3 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.7 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 1.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0060992 response to fungicide(GO:0060992)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.4 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.2 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0043586 tongue development(GO:0043586)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487) regulation of tooth mineralization(GO:0070170)
0.0 0.0 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.4 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.5 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.3 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.0 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 1.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 0.8 GO:0071754 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.1 1.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.2 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.1 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:1990879 CST complex(GO:1990879)
0.0 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.6 GO:0030057 desmosome(GO:0030057)
0.0 1.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.3 GO:1990745 EARP complex(GO:1990745)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.5 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) periciliary membrane compartment(GO:1990075)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 3.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 1.3 GO:0070821 tertiary granule membrane(GO:0070821)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.5 1.6 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.4 1.1 GO:0035375 zymogen binding(GO:0035375)
0.3 3.3 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 1.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.3 2.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2 1.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 1.3 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.5 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 4.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.6 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 2.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.5 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.5 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.5 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.7 GO:0004969 histamine receptor activity(GO:0004969)
0.1 2.3 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 1.5 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.6 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.3 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 2.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0004040 amidase activity(GO:0004040) glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 1.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 2.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.3 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 1.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.0 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.1 PID RHOA PATHWAY RhoA signaling pathway
0.0 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 3.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.0 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 3.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 2.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL