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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR4A1

Z-value: 0.64

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Transcription factors associated with NR4A1

Gene Symbol Gene ID Gene Info
NR4A1
ENSG00000123358.20 NR4A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A1hg38_v1_chr12_+_52051402_520514590.374.5e-02Click!

Activity profile of NR4A1 motif

Sorted Z-values of NR4A1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_63652663 7.57 ENST00000343837.8
ENST00000469440.5
SNTN
sentan, cilia apical structure protein
chr9_-_34397800 3.81 ENST00000297623.7
C9orf24
chromosome 9 open reading frame 24
chr11_+_73950985 3.27 ENST00000339764.6
DNAJB13
DnaJ heat shock protein family (Hsp40) member B13
chr18_-_27143024 2.40 ENST00000581714.5
CHST9
carbohydrate sulfotransferase 9
chr20_+_33168148 1.71 ENST00000354932.6
BPIFA2
BPI fold containing family A member 2
chr1_+_212565334 1.47 ENST00000366981.8
ENST00000366987.6
ATF3
activating transcription factor 3
chr9_-_72953047 1.28 ENST00000297785.8
ENST00000376939.5
ALDH1A1
aldehyde dehydrogenase 1 family member A1
chr1_-_111200633 1.27 ENST00000357640.9
DENND2D
DENN domain containing 2D
chr1_+_61404076 1.12 ENST00000357977.5
NFIA
nuclear factor I A
chr3_+_184337591 1.09 ENST00000383847.7
FAM131A
family with sequence similarity 131 member A
chr3_-_115147237 1.02 ENST00000357258.8
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_115147277 0.98 ENST00000675478.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_24972032 0.93 ENST00000534855.5
DNAJC27
DnaJ heat shock protein family (Hsp40) member C27
chrX_-_109625161 0.85 ENST00000372101.3
KCNE5
potassium voltage-gated channel subfamily E regulatory subunit 5
chr6_-_152168349 0.83 ENST00000539504.5
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr12_+_109139397 0.83 ENST00000377854.9
ENST00000377848.7
ACACB
acetyl-CoA carboxylase beta
chr5_+_73813518 0.82 ENST00000296799.8
ARHGEF28
Rho guanine nucleotide exchange factor 28
chr6_-_152168291 0.81 ENST00000354674.5
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr1_+_15736251 0.79 ENST00000294454.6
SLC25A34
solute carrier family 25 member 34
chr2_-_24971900 0.79 ENST00000264711.7
DNAJC27
DnaJ heat shock protein family (Hsp40) member C27
chr16_+_53207981 0.76 ENST00000565803.2
CHD9
chromodomain helicase DNA binding protein 9
chr4_+_70242583 0.66 ENST00000304954.3
CSN3
casein kappa
chr19_+_13023958 0.66 ENST00000587760.5
ENST00000585575.5
NFIX
nuclear factor I X
chr10_-_73591330 0.66 ENST00000451492.5
ENST00000681793.1
ENST00000680396.1
ENST00000413442.5
USP54
ubiquitin specific peptidase 54
chr1_+_174799895 0.65 ENST00000489615.5
RABGAP1L
RAB GTPase activating protein 1 like
chr14_-_77028663 0.60 ENST00000238647.5
IRF2BPL
interferon regulatory factor 2 binding protein like
chr17_+_75633420 0.58 ENST00000375215.3
SMIM5
small integral membrane protein 5
chr7_-_105876575 0.56 ENST00000318724.8
ENST00000419735.8
ATXN7L1
ataxin 7 like 1
chr6_+_31927486 0.55 ENST00000442278.6
C2
complement C2
chr14_-_35121950 0.53 ENST00000554361.5
ENST00000261475.10
PPP2R3C
protein phosphatase 2 regulatory subunit B''gamma
chr19_+_17305801 0.53 ENST00000602206.1
ENST00000252602.2
MRPL34
mitochondrial ribosomal protein L34
chr2_-_177392673 0.52 ENST00000447413.1
ENST00000397057.6
ENST00000456746.5
ENST00000464747.5
ENSG00000213963.6
NFE2L2
novel transcript
nuclear factor, erythroid 2 like 2
chr7_+_12570712 0.50 ENST00000417018.1
ENST00000297029.10
SCIN
scinderin
chr2_-_206159410 0.49 ENST00000457011.5
ENST00000440274.5
ENST00000432169.5
ENST00000233190.11
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1
chr3_+_101724602 0.49 ENST00000341893.8
CEP97
centrosomal protein 97
chr12_-_16606102 0.49 ENST00000537304.6
LMO3
LIM domain only 3
chr12_-_16605939 0.47 ENST00000541295.5
ENST00000535535.5
LMO3
LIM domain only 3
chr20_+_13008919 0.47 ENST00000399002.7
ENST00000434210.5
SPTLC3
serine palmitoyltransferase long chain base subunit 3
chr7_-_105876477 0.47 ENST00000478915.1
ATXN7L1
ataxin 7 like 1
chr12_-_16606795 0.46 ENST00000447609.5
LMO3
LIM domain only 3
chr18_-_55302613 0.45 ENST00000561831.7
TCF4
transcription factor 4
chr6_+_69232406 0.42 ENST00000238918.12
ADGRB3
adhesion G protein-coupled receptor B3
chr19_+_6372757 0.41 ENST00000245812.8
ALKBH7
alkB homolog 7
chr6_-_116060859 0.41 ENST00000606080.2
FRK
fyn related Src family tyrosine kinase
chr20_+_11917859 0.39 ENST00000618296.4
ENST00000378226.7
BTBD3
BTB domain containing 3
chr11_+_3855629 0.39 ENST00000526596.2
ENST00000300737.8
ENST00000616714.4
STIM1
stromal interaction molecule 1
chr14_-_95157270 0.37 ENST00000674628.1
ENST00000529720.1
ENST00000393063.6
ENST00000532939.3
DICER1
dicer 1, ribonuclease III
chr10_-_17129786 0.36 ENST00000377833.10
CUBN
cubilin
chr3_+_138621207 0.35 ENST00000464668.5
FAIM
Fas apoptotic inhibitory molecule
chr15_+_43692886 0.34 ENST00000434505.5
ENST00000411750.5
CKMT1A
creatine kinase, mitochondrial 1A
chr6_+_63636481 0.34 ENST00000509330.5
PHF3
PHD finger protein 3
chr4_-_73223082 0.33 ENST00000509867.6
ANKRD17
ankyrin repeat domain 17
chr3_+_138621225 0.32 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr19_+_49210734 0.31 ENST00000597316.1
TRPM4
transient receptor potential cation channel subfamily M member 4
chr7_-_73522278 0.30 ENST00000404251.1
ENST00000339594.9
BAZ1B
bromodomain adjacent to zinc finger domain 1B
chr2_+_233307806 0.30 ENST00000447536.5
ENST00000409110.6
SAG
S-antigen visual arrestin
chr1_+_13749408 0.29 ENST00000343137.8
ENST00000503842.5
ENST00000407521.7
ENST00000505823.5
PRDM2
PR/SET domain 2
chr20_+_17699942 0.29 ENST00000427254.1
ENST00000377805.7
BANF2
BANF family member 2
chr7_-_37448845 0.29 ENST00000310758.9
ELMO1
engulfment and cell motility 1
chr6_-_152637351 0.29 ENST00000367255.10
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr8_+_122781621 0.29 ENST00000314393.6
ZHX2
zinc fingers and homeoboxes 2
chr17_-_7219813 0.28 ENST00000399510.8
ENST00000648172.8
DLG4
discs large MAGUK scaffold protein 4
chr10_+_99782628 0.28 ENST00000648689.1
ENST00000647814.1
ABCC2
ATP binding cassette subfamily C member 2
chr18_-_5197241 0.27 ENST00000434239.4
AKAIN1
A-kinase anchor inhibitor 1
chr18_+_58196736 0.27 ENST00000675221.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr3_+_29280945 0.27 ENST00000434693.6
RBMS3
RNA binding motif single stranded interacting protein 3
chr10_-_59906509 0.26 ENST00000263102.7
CCDC6
coiled-coil domain containing 6
chr17_-_68291116 0.25 ENST00000327268.8
ENST00000580666.6
SLC16A6
solute carrier family 16 member 6
chr14_-_95157482 0.25 ENST00000343455.8
DICER1
dicer 1, ribonuclease III
chr6_+_31927683 0.24 ENST00000456570.5
ENSG00000244255.5
novel complement component 2 (C2) and complement factor B (CFB) protein
chr4_-_56387422 0.24 ENST00000513376.5
ENST00000205214.11
ENST00000502617.1
ENST00000451613.5
ENST00000602986.5
AASDH
aminoadipate-semialdehyde dehydrogenase
chr19_-_11529094 0.23 ENST00000588998.5
ENST00000586149.1
ECSIT
ECSIT signaling integrator
chr20_+_17699960 0.23 ENST00000246090.6
BANF2
BANF family member 2
chr20_-_45857196 0.23 ENST00000457981.5
ENST00000426915.1
ENST00000217455.9
ACOT8
acyl-CoA thioesterase 8
chr15_-_42491105 0.22 ENST00000565380.5
ENST00000564754.7
ZNF106
zinc finger protein 106
chr19_-_11529116 0.21 ENST00000592312.5
ENST00000590480.1
ENST00000585318.5
ENST00000270517.12
ENST00000252440.11
ENST00000417981.6
ECSIT
ECSIT signaling integrator
chr1_+_228208054 0.21 ENST00000284548.16
ENST00000422127.5
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr16_-_81198766 0.21 ENST00000526632.5
PKD1L2
polycystin 1 like 2 (gene/pseudogene)
chr5_-_74866779 0.21 ENST00000510496.5
FAM169A
family with sequence similarity 169 member A
chr20_+_38962299 0.20 ENST00000373325.6
ENST00000373323.8
ENST00000252011.8
ENST00000615559.1
DHX35
ENSG00000277581.1
DEAH-box helicase 35
novel transcript, sense intronic to DHX35
chr4_-_88823165 0.20 ENST00000508369.5
FAM13A
family with sequence similarity 13 member A
chr22_-_50578417 0.18 ENST00000312108.12
ENST00000395650.6
CPT1B
carnitine palmitoyltransferase 1B
chr4_-_88823306 0.18 ENST00000395002.6
FAM13A
family with sequence similarity 13 member A
chr4_-_86358487 0.17 ENST00000641066.1
ENST00000512689.6
ENST00000641803.1
ENST00000640970.1
ENST00000641983.1
MAPK10
mitogen-activated protein kinase 10
chr16_-_31150058 0.16 ENST00000569305.1
ENST00000268281.9
ENST00000418068.6
PRSS36
serine protease 36
chr3_+_14947680 0.16 ENST00000435454.5
ENST00000323373.10
NR2C2
nuclear receptor subfamily 2 group C member 2
chr1_+_40247926 0.15 ENST00000372766.4
TMCO2
transmembrane and coiled-coil domains 2
chr3_-_44477639 0.15 ENST00000396077.8
ZNF445
zinc finger protein 445
chr20_+_58891981 0.14 ENST00000488652.6
ENST00000476935.6
ENST00000492907.6
ENST00000603546.2
GNAS
GNAS complex locus
chr1_+_228208024 0.14 ENST00000570156.7
ENST00000680850.1
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr3_+_14947568 0.14 ENST00000413118.5
ENST00000425241.5
NR2C2
nuclear receptor subfamily 2 group C member 2
chr4_-_88823214 0.13 ENST00000513837.5
ENST00000503556.5
FAM13A
family with sequence similarity 13 member A
chr17_+_42998264 0.13 ENST00000589037.5
RPL27
ribosomal protein L27
chr15_+_75043263 0.13 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr2_+_176157293 0.12 ENST00000683222.1
HOXD3
homeobox D3
chr9_-_136245802 0.12 ENST00000358701.10
QSOX2
quiescin sulfhydryl oxidase 2
chr6_+_31927703 0.12 ENST00000418949.6
ENST00000299367.10
ENST00000383177.7
ENST00000477310.1
C2
ENSG00000244255.5
complement C2
novel complement component 2 (C2) and complement factor B (CFB) protein
chr16_+_31355165 0.12 ENST00000562918.5
ENST00000268296.9
ITGAX
integrin subunit alpha X
chr18_+_46174014 0.12 ENST00000619301.4
ENST00000615052.5
C18orf25
chromosome 18 open reading frame 25
chr17_+_42998379 0.12 ENST00000253788.12
ENST00000589913.6
RPL27
ribosomal protein L27
chr12_+_53985138 0.12 ENST00000303460.5
HOXC10
homeobox C10
chr15_+_36594868 0.12 ENST00000566807.5
ENST00000643612.1
ENST00000567389.5
ENST00000562877.5
CDIN1
CDAN1 interacting nuclease 1
chr10_-_126670686 0.11 ENST00000488181.3
C10orf90
chromosome 10 open reading frame 90
chr8_+_132775340 0.11 ENST00000622263.4
ENST00000220847.8
ENST00000395379.5
ENST00000395386.7
ENST00000485595.5
ENST00000337920.8
PHF20L1
PHD finger protein 20 like 1
chr7_-_6009072 0.10 ENST00000642456.1
ENST00000642292.1
ENST00000441476.6
PMS2
PMS1 homolog 2, mismatch repair system component
chr3_+_113747022 0.10 ENST00000273398.8
ENST00000496747.5
ENST00000475322.1
ATP6V1A
ATPase H+ transporting V1 subunit A
chr20_-_44187153 0.10 ENST00000372980.4
JPH2
junctophilin 2
chr6_-_33803980 0.09 ENST00000507738.1
ENST00000266003.9
ENST00000430124.7
MLN
motilin
chr20_+_45857607 0.08 ENST00000255152.3
ZSWIM3
zinc finger SWIM-type containing 3
chr3_+_184320283 0.08 ENST00000428387.5
ENST00000434061.6
EIF4G1
eukaryotic translation initiation factor 4 gamma 1
chr10_+_35195843 0.07 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr12_+_57941499 0.07 ENST00000300145.4
ATP23
ATP23 metallopeptidase and ATP synthase assembly factor homolog
chr2_-_43995950 0.07 ENST00000683590.1
ENST00000683623.1
ENST00000682779.1
ENST00000682546.1
ENST00000683220.1
ENST00000683125.1
ENST00000683833.1
ENST00000683989.1
ENST00000682480.1
ENST00000260665.12
ENST00000682308.1
ENST00000682885.1
ENST00000409659.6
ENST00000447246.2
LRPPRC
leucine rich pentatricopeptide repeat containing
chr17_+_7219857 0.06 ENST00000583312.5
ENST00000350303.9
ENST00000584103.5
ENST00000356839.10
ENST00000579886.2
ACADVL
acyl-CoA dehydrogenase very long chain
chr3_+_184319677 0.06 ENST00000441154.5
EIF4G1
eukaryotic translation initiation factor 4 gamma 1
chr2_-_43995999 0.06 ENST00000683213.1
ENST00000409946.6
LRPPRC
leucine rich pentatricopeptide repeat containing
chr14_-_95157890 0.06 ENST00000526495.6
DICER1
dicer 1, ribonuclease III
chr19_-_5622768 0.05 ENST00000252542.9
SAFB2
scaffold attachment factor B2
chr17_-_31297231 0.05 ENST00000247271.5
OMG
oligodendrocyte myelin glycoprotein
chr7_-_6009019 0.05 ENST00000382321.5
ENST00000265849.12
PMS2
PMS1 homolog 2, mismatch repair system component
chr1_+_165631199 0.05 ENST00000367888.8
ENST00000367889.8
ENST00000367885.5
ENST00000367884.6
MGST3
microsomal glutathione S-transferase 3
chr7_+_6009222 0.04 ENST00000400479.6
ENST00000223029.8
ENST00000395236.2
AIMP2
aminoacyl tRNA synthetase complex interacting multifunctional protein 2
chr13_-_32538683 0.04 ENST00000674456.1
ENST00000504114.5
N4BP2L2
NEDD4 binding protein 2 like 2
chr18_+_46174055 0.03 ENST00000615553.1
C18orf25
chromosome 18 open reading frame 25
chr3_-_157503339 0.03 ENST00000392833.6
VEPH1
ventricular zone expressed PH domain containing 1
chr3_-_157503375 0.03 ENST00000362010.7
VEPH1
ventricular zone expressed PH domain containing 1
chr17_+_42998779 0.03 ENST00000586277.5
RPL27
ribosomal protein L27
chr7_+_121328991 0.03 ENST00000222462.3
WNT16
Wnt family member 16
chr4_-_40630588 0.03 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr17_+_1742836 0.02 ENST00000324015.7
ENST00000450523.6
ENST00000453723.5
ENST00000453066.6
ENST00000382061.5
SERPINF2
serpin family F member 2
chr17_-_68291168 0.02 ENST00000582867.1
SLC16A6
solute carrier family 16 member 6
chr2_-_27380715 0.02 ENST00000323703.11
ENST00000436006.1
ZNF513
zinc finger protein 513
chr11_+_278398 0.02 ENST00000534750.6
NLRP6
NLR family pyrin domain containing 6
chr11_+_116829898 0.01 ENST00000227667.8
ENST00000375345.3
APOC3
apolipoprotein C3
chr8_-_119673368 0.01 ENST00000427067.6
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr5_-_127073467 0.01 ENST00000607731.5
ENST00000509733.7
ENST00000296662.10
ENST00000535381.6
C5orf63
chromosome 5 open reading frame 63
chr6_+_30626842 0.00 ENST00000318999.11
ENST00000376485.8
ENST00000330083.6
ENST00000319027.9
ENST00000376483.8
ENST00000329992.12
ATAT1
alpha tubulin acetyltransferase 1
chr17_-_2266131 0.00 ENST00000570606.5
ENST00000354901.8
SMG6
SMG6 nonsense mediated mRNA decay factor
chr3_-_157503574 0.00 ENST00000494677.5
ENST00000468233.5
VEPH1
ventricular zone expressed PH domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.5 1.5 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 1.7 GO:0045204 MAPK export from nucleus(GO:0045204)
0.2 0.7 GO:0036404 conversion of ds siRNA to ss siRNA involved in RNA interference(GO:0033168) conversion of ds siRNA to ss siRNA(GO:0036404)
0.2 1.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 1.3 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 1.9 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2 0.8 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.5 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.4 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.3 GO:1903949 positive regulation of atrial cardiac muscle cell action potential(GO:1903949)
0.1 0.4 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.3 GO:0016999 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.1 0.8 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1 0.3 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 2.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.6 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.5 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 1.1 GO:0072189 ureter development(GO:0072189)
0.0 2.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.5 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.0 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.3 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.5 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.4 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 1.7 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 0.7 GO:0033167 ARC complex(GO:0033167)
0.1 1.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.4 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.5 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 3.3 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 7.2 GO:0005929 cilium(GO:0005929)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0034706 sodium channel complex(GO:0034706)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 1.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 0.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.7 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.5 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.2 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.1 0.3 GO:0002046 opsin binding(GO:0002046)
0.1 1.9 GO:0005521 lamin binding(GO:0005521)
0.0 1.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.8 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 2.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 3.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.0 0.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.5 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.7 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism