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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR4A3

Z-value: 0.62

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Transcription factors associated with NR4A3

Gene Symbol Gene ID Gene Info
ENSG00000119508.18 NR4A3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A3hg38_v1_chr9_+_99821846_998218620.212.7e-01Click!

Activity profile of NR4A3 motif

Sorted Z-values of NR4A3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_+_63652663 4.30 ENST00000343837.8
ENST00000469440.5
sentan, cilia apical structure protein
chr9_-_127874964 1.72 ENST00000373156.5
adenylate kinase 1
chr9_+_69820799 1.70 ENST00000377197.8
chromosome 9 open reading frame 135
chr16_+_2830295 1.68 ENST00000571723.1
zymogen granule protein 16B
chr8_-_109691766 1.49 ENST00000529190.5
ENST00000422135.5
syntabulin
chr9_-_72953047 1.45 ENST00000297785.8
ENST00000376939.5
aldehyde dehydrogenase 1 family member A1
chr6_+_33080445 1.31 ENST00000428835.5
major histocompatibility complex, class II, DP beta 1
chr3_-_167380270 1.28 ENST00000392764.5
ENST00000675490.1
ENST00000474464.5
ENST00000392766.6
ENST00000485651.5
zinc finger B-box domain containing
chr16_+_2830368 1.27 ENST00000572863.1
zymogen granule protein 16B
chr1_+_162381703 1.19 ENST00000458626.4
chromosome 1 open reading frame 226
chr3_+_13568721 1.17 ENST00000492059.5
fibulin 2
chr13_-_52011337 1.13 ENST00000400366.6
ENST00000400370.8
ENST00000634844.1
ENST00000673772.1
ENST00000418097.7
ENST00000242839.10
ENST00000344297.9
ENST00000448424.7
ATPase copper transporting beta
chr9_-_4299547 1.11 ENST00000682749.1
GLIS family zinc finger 3
chr16_+_2830179 1.10 ENST00000570670.5
zymogen granule protein 16B
chr2_-_73233206 1.06 ENST00000258083.3
protease associated domain containing 1
chr1_+_103750406 1.02 ENST00000370079.3
amylase alpha 1C
chr20_+_33168148 0.99 ENST00000354932.6
BPI fold containing family A member 2
chr16_+_2830155 0.95 ENST00000382280.7
zymogen granule protein 16B
chr7_+_121873089 0.93 ENST00000651065.1
protein tyrosine phosphatase receptor type Z1
chr18_-_27143024 0.92 ENST00000581714.5
carbohydrate sulfotransferase 9
chr7_-_131556602 0.90 ENST00000322985.9
ENST00000378555.8
podocalyxin like
chr5_-_42811884 0.88 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr4_+_41612892 0.88 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIM and calponin homology domains 1
chr9_+_69820827 0.86 ENST00000527647.5
ENST00000480564.1
chromosome 9 open reading frame 135
chr1_-_36440873 0.86 ENST00000433045.6
organic solute carrier partner 1
chr22_+_31122923 0.83 ENST00000620191.4
ENST00000412277.6
ENST00000412985.5
ENST00000331075.10
ENST00000420017.5
ENST00000400294.6
ENST00000405300.5
ENST00000404390.7
inositol polyphosphate-5-phosphatase J
chr14_-_21024092 0.81 ENST00000554398.5
NDRG family member 2
chr14_-_21023954 0.78 ENST00000554094.5
NDRG family member 2
chr5_-_16616972 0.77 ENST00000682564.1
ENST00000306320.10
ENST00000682229.1
reticulophagy regulator 1
chr3_+_158571153 0.77 ENST00000491767.6
ENST00000618075.4
myeloid leukemia factor 1
chr3_-_9952337 0.77 ENST00000411976.2
ENST00000412055.6
proline rich transmembrane protein 3
chr3_+_158571215 0.76 ENST00000498592.6
ENST00000478894.7
myeloid leukemia factor 1
chr7_+_121873152 0.75 ENST00000650826.1
ENST00000650728.1
ENST00000393386.7
ENST00000651390.1
ENST00000651842.1
ENST00000650681.1
protein tyrosine phosphatase receptor type Z1
chr1_+_61082702 0.75 ENST00000485903.6
ENST00000371185.6
ENST00000371184.6
nuclear factor I A
chr1_-_36450279 0.74 ENST00000445843.7
organic solute carrier partner 1
chr3_+_113897470 0.72 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr11_+_6863057 0.71 ENST00000641461.1
olfactory receptor family 10 subfamily A member 2
chr3_+_158571171 0.69 ENST00000484955.5
ENST00000359117.9
ENST00000619577.5
ENST00000471745.5
ENST00000477042.6
ENST00000650753.1
ENST00000651984.1
ENST00000355893.11
ENST00000466246.7
ENST00000469452.5
ENST00000482628.5
myeloid leukemia factor 1
chr14_-_24442241 0.68 ENST00000555355.5
ENST00000553343.5
ENST00000556523.1
ENST00000556249.1
ENST00000538105.6
ENST00000555225.5
short chain dehydrogenase/reductase family 39U member 1
chr3_+_113948004 0.67 ENST00000638807.2
zinc finger DHHC-type palmitoyltransferase 23
chr6_+_33075952 0.67 ENST00000418931.7
major histocompatibility complex, class II, DP beta 1
chr14_+_22515623 0.67 ENST00000390509.1
T cell receptor alpha joining 28
chr16_+_67806765 0.66 ENST00000415766.7
ENST00000561639.6
translin associated factor X interacting protein 1
chr1_-_36450410 0.66 ENST00000356637.9
ENST00000354267.3
ENST00000235532.9
organic solute carrier partner 1
chr2_-_237590660 0.66 ENST00000409576.1
RAB17, member RAS oncogene family
chr3_+_113947901 0.66 ENST00000330212.7
ENST00000498275.5
zinc finger DHHC-type palmitoyltransferase 23
chr11_-_47715344 0.65 ENST00000525123.6
ENST00000528244.5
ENST00000532595.5
ENST00000529154.5
ENST00000530969.1
ATP/GTP binding protein like 2
chr14_-_53953415 0.65 ENST00000559501.1
ENST00000558984.1
bone morphogenetic protein 4
chr4_+_41612702 0.65 ENST00000509277.5
LIM and calponin homology domains 1
chr11_+_36375978 0.64 ENST00000378867.7
proline rich 5 like
chr19_-_48364034 0.64 ENST00000435956.7
transmembrane protein 143
chr7_-_138701352 0.63 ENST00000421622.5
ENST00000674285.1
SVOP like
chr8_+_135457442 0.61 ENST00000355849.10
KH RNA binding domain containing, signal transduction associated 3
chr14_+_21030509 0.61 ENST00000481535.5
tubulin polymerization promoting protein family member 2
chr19_-_48363914 0.60 ENST00000377431.6
ENST00000293261.8
transmembrane protein 143
chr2_+_88691647 0.60 ENST00000283646.5
ribose 5-phosphate isomerase A
chr17_-_43942472 0.59 ENST00000225992.8
pancreatic polypeptide
chr16_+_67807082 0.59 ENST00000567852.5
ENST00000565148.5
ENST00000388833.7
ENST00000561654.5
ENST00000431934.2
translin associated factor X interacting protein 1
chr1_+_61082398 0.58 ENST00000664149.1
nuclear factor I A
chr2_-_30807411 0.54 ENST00000295055.12
calpain 13
chr1_+_61082553 0.54 ENST00000403491.8
ENST00000371187.7
nuclear factor I A
chr19_+_35139724 0.53 ENST00000588715.5
ENST00000588607.5
FXYD domain containing ion transport regulator 1
chr9_-_127877665 0.52 ENST00000644144.2
adenylate kinase 1
chr14_+_73569266 0.51 ENST00000613168.1
acyl-CoA thioesterase 2
chr12_+_108129276 0.51 ENST00000547525.6
WSC domain containing 2
chr7_-_95396349 0.51 ENST00000427422.5
ENST00000451904.5
ENST00000265627.10
paraoxonase 3
chr9_-_35749165 0.51 ENST00000378094.4
ENST00000378103.7
glucosylceramidase beta 2
chr19_+_35138778 0.51 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD domain containing ion transport regulator 1
novel transcript
chr5_+_36606355 0.50 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr3_-_58666765 0.49 ENST00000358781.7
FAM3 metabolism regulating signaling molecule D
chr2_+_24491860 0.49 ENST00000406961.5
ENST00000405141.5
nuclear receptor coactivator 1
chr2_-_27890348 0.49 ENST00000302188.8
ribokinase
chr12_+_12070932 0.48 ENST00000308721.9
BCL2 like 14
chr22_-_23767876 0.48 ENST00000520222.1
ENST00000401675.7
ENST00000484558.3
coiled-coil-helix-coiled-coil-helix domain containing 10
chr16_-_53703810 0.47 ENST00000569716.1
ENST00000562588.5
ENST00000621565.5
ENST00000562230.5
ENST00000563746.5
ENST00000568653.7
ENST00000647211.2
RPGRIP1 like
chr10_-_114526804 0.47 ENST00000369266.7
ENST00000369253.6
actin binding LIM protein 1
chr8_+_98944403 0.47 ENST00000457907.3
ENST00000523368.5
ENST00000297565.8
ENST00000435298.6
odd-skipped related transciption factor 2
chr16_-_53703883 0.46 ENST00000262135.9
ENST00000564374.5
ENST00000566096.5
RPGRIP1 like
chr14_-_22819721 0.46 ENST00000554517.5
ENST00000285850.11
ENST00000397529.6
ENST00000555702.5
solute carrier family 7 member 7
chr11_+_63369779 0.46 ENST00000279178.4
solute carrier family 22 member 9
chr20_+_44582549 0.45 ENST00000372886.6
cAMP-dependent protein kinase inhibitor gamma
chr2_+_28981295 0.45 ENST00000379558.5
TOG array regulator of axonemal microtubules 2
chr12_-_122730828 0.45 ENST00000432564.3
hydroxycarboxylic acid receptor 1
chr20_+_59604527 0.45 ENST00000371015.6
phosphatase and actin regulator 3
chr2_-_237590694 0.45 ENST00000264601.8
ENST00000411462.5
ENST00000409822.1
RAB17, member RAS oncogene family
chr10_-_73591330 0.45 ENST00000451492.5
ENST00000681793.1
ENST00000680396.1
ENST00000413442.5
ubiquitin specific peptidase 54
chr19_+_17305801 0.44 ENST00000602206.1
ENST00000252602.2
mitochondrial ribosomal protein L34
chr7_-_5967204 0.43 ENST00000337579.4
radial spoke head 10 homolog B
chr16_-_67416420 0.43 ENST00000348579.6
ENST00000565726.3
zinc finger DHHC-type containing 1
chr4_+_76074701 0.43 ENST00000355810.9
ENST00000349321.7
ADP-ribosyltransferase 3 (inactive)
chr19_-_3062464 0.42 ENST00000327141.9
TLE family member 5, transcriptional modulator
chr7_+_23598144 0.42 ENST00000410069.1
coiled-coil domain containing 126
chr2_+_27014746 0.42 ENST00000648289.1
ENST00000458529.5
ENST00000402218.1
microtubule associated protein RP/EB family member 3
chr10_-_114684457 0.41 ENST00000392955.7
actin binding LIM protein 1
chr19_+_48624952 0.41 ENST00000599748.5
ENST00000599029.2
sphingosine kinase 2
chr4_-_687325 0.41 ENST00000503156.5
solute carrier family 49 member 3
chr15_-_26939518 0.41 ENST00000541819.6
gamma-aminobutyric acid type A receptor subunit beta3
chr12_-_91182652 0.40 ENST00000552145.5
ENST00000546745.5
decorin
chr10_-_114684612 0.40 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr10_-_20897288 0.40 ENST00000377122.9
nebulette
chr7_-_945799 0.39 ENST00000611167.4
ArfGAP with dual PH domains 1
chr17_+_42288429 0.39 ENST00000676631.1
ENST00000677893.1
signal transducer and activator of transcription 5A
chr5_+_114056017 0.39 ENST00000512097.9
potassium calcium-activated channel subfamily N member 2
chr10_+_79347491 0.39 ENST00000448165.1
peptidylprolyl isomerase F
chr1_+_145927105 0.38 ENST00000437797.5
ENST00000601726.3
ENST00000599626.5
ENST00000599147.5
ENST00000595494.5
ENST00000595518.5
ENST00000597144.5
ENST00000599469.5
ENST00000598354.5
ENST00000598103.5
ENST00000600340.5
ENST00000630257.2
ENST00000625258.1
LIX1L antisense RNA 1
novel protein, lncRNA-POLR3GL readthrough
chr11_-_8810635 0.38 ENST00000527510.5
ENST00000528527.5
ENST00000313726.11
ENST00000528523.5
DENN domain containing 2B
chr17_+_42288464 0.38 ENST00000590726.7
ENST00000678903.1
ENST00000590949.6
ENST00000676585.1
ENST00000588868.5
signal transducer and activator of transcription 5A
chr3_-_49277209 0.38 ENST00000436325.1
ENST00000343010.8
chromosome 3 open reading frame 62
chr1_+_151156627 0.37 ENST00000368910.4
TNF alpha induced protein 8 like 2
chr19_-_3062772 0.37 ENST00000586742.5
TLE family member 5, transcriptional modulator
chr6_+_158649997 0.37 ENST00000360448.8
ENST00000367081.7
ENST00000611299.5
synaptotagmin like 3
chr20_-_18467023 0.37 ENST00000262547.9
double zinc ribbon and ankyrin repeat domains 1
chr1_-_183590596 0.36 ENST00000418089.5
ENST00000413720.5
neutrophil cytosolic factor 2
chr14_-_24442662 0.36 ENST00000554698.5
short chain dehydrogenase/reductase family 39U member 1
chr19_-_4581755 0.36 ENST00000676793.1
semaphorin 6B
chr6_+_18155399 0.35 ENST00000650836.2
ENST00000449850.2
ENST00000297792.9
lysine demethylase 1B
chr9_-_136944725 0.35 ENST00000325285.8
F-box and WD repeat domain containing 5
chr11_-_73976952 0.35 ENST00000545212.1
uncoupling protein 2
chr17_-_40648646 0.35 ENST00000643318.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr11_+_3855629 0.34 ENST00000526596.2
ENST00000300737.8
ENST00000616714.4
stromal interaction molecule 1
chr5_+_140639494 0.34 ENST00000252100.6
transmembrane and coiled-coil domains 6
chr1_-_19799872 0.34 ENST00000294543.11
transmembrane and coiled-coil domains 4
chr11_-_117828698 0.34 ENST00000528014.5
FXYD domain containing ion transport regulator 2
chr14_-_31420531 0.34 ENST00000382464.6
ENST00000543095.7
HEAT repeat containing 5A
chr7_-_73738792 0.34 ENST00000222800.8
ENST00000458339.6
abhydrolase domain containing 11
chr1_+_160127672 0.33 ENST00000447527.1
ATPase Na+/K+ transporting subunit alpha 2
chr11_-_8932944 0.33 ENST00000326053.10
ENST00000525780.5
chromosome 11 open reading frame 16
chr16_-_19886133 0.33 ENST00000568214.1
ENST00000569479.5
G protein-coupled receptor class C group 5 member B
chr19_+_49210734 0.33 ENST00000597316.1
transient receptor potential cation channel subfamily M member 4
chr22_+_35383106 0.32 ENST00000678411.1
heme oxygenase 1
chr1_-_11047225 0.32 ENST00000400898.3
ENST00000400897.8
mannan binding lectin serine peptidase 2
chr2_-_241637045 0.32 ENST00000407315.6
THAP domain containing 4
chr11_-_117828068 0.32 ENST00000532119.5
ENST00000260287.2
FXYD domain containing ion transport regulator 2
chr7_+_92057602 0.32 ENST00000491695.2
A-kinase anchoring protein 9
chr15_-_43330537 0.32 ENST00000305641.7
ENST00000567039.1
leucine carboxyl methyltransferase 2
chr20_-_33720221 0.32 ENST00000409299.8
ENST00000217398.3
ENST00000344022.7
peroxisomal membrane protein 4
chr7_-_151080833 0.32 ENST00000353841.6
ENST00000482571.2
Fas activated serine/threonine kinase
chr7_-_73738831 0.31 ENST00000395147.9
ENST00000437775.7
abhydrolase domain containing 11
chr5_+_73813518 0.31 ENST00000296799.8
Rho guanine nucleotide exchange factor 28
chrX_-_100731504 0.31 ENST00000372989.5
ENST00000276141.10
synaptotagmin like 4
chr16_+_28863812 0.31 ENST00000684370.1
SH2B adaptor protein 1
chr7_-_151080787 0.31 ENST00000540185.5
ENST00000297532.11
Fas activated serine/threonine kinase
chr22_+_44676808 0.31 ENST00000624862.3
proline rich 5
chr1_+_212565334 0.30 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr16_+_69762309 0.30 ENST00000561780.5
ENST00000359154.7
ENST00000563659.5
WW domain containing E3 ubiquitin protein ligase 2
chr3_-_126056786 0.30 ENST00000383598.6
solute carrier family 41 member 3
chr10_-_98446878 0.29 ENST00000338546.9
ENST00000325103.10
ENST00000361490.9
HPS1 biogenesis of lysosomal organelles complex 3 subunit 1
chr3_+_108822759 0.29 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chr17_-_55511434 0.29 ENST00000636752.1
small integral membrane protein 36
chr10_+_102245371 0.29 ENST00000676513.1
ENST00000676939.1
ENST00000677947.1
ENST00000677247.1
ENST00000369983.4
ENST00000678351.1
ENST00000679238.1
ENST00000677439.1
ENST00000677240.1
ENST00000677618.1
ENST00000673650.1
ENST00000674034.1
ENST00000676993.1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr12_-_42483958 0.29 ENST00000548696.6
ENST00000552240.6
prickle planar cell polarity protein 1
chrX_-_109625161 0.29 ENST00000372101.3
potassium voltage-gated channel subfamily E regulatory subunit 5
chr12_+_53423849 0.29 ENST00000257863.9
ENST00000550311.5
ENST00000379791.7
anti-Mullerian hormone receptor type 2
chr17_-_63440817 0.29 ENST00000580592.1
ENST00000392975.6
cytochrome b561
chr3_+_108822778 0.29 ENST00000295756.11
T cell receptor associated transmembrane adaptor 1
chr21_-_35049327 0.29 ENST00000300305.7
RUNX family transcription factor 1
chr3_+_155870623 0.29 ENST00000295920.7
ENST00000496455.7
guanine monophosphate synthase
chr12_+_120725796 0.29 ENST00000242592.9
ENST00000411593.2
acyl-CoA dehydrogenase short chain
chr16_+_28863757 0.28 ENST00000618521.4
ENST00000359285.9
ENST00000538342.5
SH2B adaptor protein 1
chr14_-_21023318 0.28 ENST00000298684.9
ENST00000557169.5
ENST00000553563.5
NDRG family member 2
chr2_-_206159410 0.28 ENST00000457011.5
ENST00000440274.5
ENST00000432169.5
ENST00000233190.11
NADH:ubiquinone oxidoreductase core subunit S1
chr22_+_29767351 0.28 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr16_+_57620077 0.27 ENST00000567835.5
ENST00000569372.5
ENST00000563548.5
ENST00000562003.5
adhesion G protein-coupled receptor G1
chr16_-_81198766 0.27 ENST00000526632.5
polycystin 1 like 2 (gene/pseudogene)
chr1_-_27366917 0.27 ENST00000357582.3
mitogen-activated protein kinase kinase kinase 6
chr10_-_28282086 0.27 ENST00000375719.7
ENST00000375732.5
membrane palmitoylated protein 7
chr3_+_184337591 0.27 ENST00000383847.7
family with sequence similarity 131 member A
chr16_-_67936808 0.26 ENST00000358514.9
proteasome 20S subunit beta 10
chr21_+_41168142 0.26 ENST00000330333.11
beta-secretase 2
chr22_+_20774092 0.26 ENST00000215727.10
serpin family D member 1
chr1_+_210329294 0.25 ENST00000367010.5
hedgehog acyltransferase
chr22_+_22409755 0.25 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr3_+_51943244 0.25 ENST00000498510.2
poly(ADP-ribose) polymerase family member 3
chr17_+_42980547 0.25 ENST00000361677.5
ENST00000589705.1
RUN domain containing 1
chr11_-_707063 0.24 ENST00000683307.1
DEAF1 transcription factor
chr19_-_3063101 0.24 ENST00000221561.12
TLE family member 5, transcriptional modulator
chr2_-_24972032 0.24 ENST00000534855.5
DnaJ heat shock protein family (Hsp40) member C27
chr19_+_10086787 0.24 ENST00000590378.5
ENST00000397881.7
shiftless antiviral inhibitor of ribosomal frameshifting
chr14_-_89412025 0.24 ENST00000553840.5
ENST00000556916.5
forkhead box N3
chr8_+_95133940 0.24 ENST00000519516.1
pleckstrin homology and FYVE domain containing 2
chr11_+_10455292 0.24 ENST00000396553.6
adenosine monophosphate deaminase 3
chr16_-_28925172 0.24 ENST00000544477.5
ENST00000357573.10
ENST00000358201.9
rabaptin, RAB GTPase binding effector protein 2
chr7_-_6009072 0.24 ENST00000642456.1
ENST00000642292.1
ENST00000441476.6
PMS1 homolog 2, mismatch repair system component
chr2_+_97646034 0.24 ENST00000258424.3
cytochrome c oxidase subunit 5B
chr22_+_44677044 0.24 ENST00000006251.11
proline rich 5
chr1_+_206470463 0.24 ENST00000581977.7
ENST00000578328.6
ENST00000584998.5
ENST00000579827.6
inhibitor of nuclear factor kappa B kinase subunit epsilon
chr22_+_44677077 0.23 ENST00000403581.5
proline rich 5
chr19_+_6372757 0.23 ENST00000245812.8
alkB homolog 7
chrX_+_141880562 0.23 ENST00000443323.2
MAGE family member C3
chr5_+_111223905 0.23 ENST00000512453.5
calcium/calmodulin dependent protein kinase IV
chr19_+_2328663 0.23 ENST00000614794.4
ENST00000613503.5
ENST00000610743.4
ENST00000618220.4
signal peptide peptidase like 2B
chr3_-_45958572 0.23 ENST00000433878.5
FYVE and coiled-coil domain autophagy adaptor 1
chr13_-_46105009 0.23 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
carboxypeptidase B2
chr14_-_24442765 0.23 ENST00000555365.5
ENST00000399395.8
ENST00000553930.5
short chain dehydrogenase/reductase family 39U member 1
chr11_-_1762403 0.22 ENST00000367196.4
cathepsin D
chr4_-_40630588 0.22 ENST00000514014.1
RNA binding motif protein 47
chr11_-_117876612 0.22 ENST00000584230.1
ENST00000526014.6
ENST00000584394.5
ENST00000614497.5
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr15_+_45129933 0.22 ENST00000321429.8
ENST00000389037.7
ENST00000558322.5
dual oxidase 1
chr4_-_1721313 0.22 ENST00000382936.8
ENST00000536901.1
ENST00000303277.6
transmembrane protein 129, E3 ubiquitin ligase
chr6_+_37005630 0.22 ENST00000274963.13
FYVE, RhoGEF and PH domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0060003 copper ion export(GO:0060003)
0.4 1.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.3 2.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.3 1.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.2 0.9 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 0.6 GO:0072099 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 1.5 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 1.0 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.2 0.5 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.2 0.5 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.2 0.6 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.4 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.5 GO:2000984 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.1 0.9 GO:0061709 reticulophagy(GO:0061709)
0.1 0.3 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 1.9 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.7 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.3 GO:1903949 positive regulation of atrial cardiac muscle cell action potential(GO:1903949)
0.1 0.3 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.1 0.7 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 1.7 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.4 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.4 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.9 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 1.4 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.3 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.3 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.5 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 0.2 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.1 0.5 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.7 GO:0036376 sodium ion export from cell(GO:0036376)
0.1 0.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.2 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.1 0.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.3 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.1 1.8 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:2000690 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.3 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.2 GO:0042335 cuticle development(GO:0042335)
0.1 0.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.5 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 1.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.9 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.5 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.2 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.0 0.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.7 GO:0099624 atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0 0.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 3.4 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 2.0 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 1.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0051792 short-chain fatty acid biosynthetic process(GO:0051790) medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.3 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.0 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.2 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:0072144 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.3 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.3 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.4 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:2000620 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.8 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 1.4 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:1904980 positive regulation of endosome organization(GO:1904980)
0.0 0.1 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0 0.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 2.3 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.6 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.4 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0036101 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.2 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.1 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.0 1.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0072534 perineuronal net(GO:0072534)
0.1 0.4 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.1 2.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.5 GO:0097433 dense body(GO:0097433)
0.1 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 2.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.0 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.3 GO:0044307 dendritic branch(GO:0044307)
0.1 1.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0070470 plasma membrane respiratory chain(GO:0070470)
0.1 0.5 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 1.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.4 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.4 GO:0032010 phagolysosome(GO:0032010)
0.0 2.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 0.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.3 0.9 GO:0031862 prostanoid receptor binding(GO:0031862)
0.2 1.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 0.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 1.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.5 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 2.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.5 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.3 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.8 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.3 GO:0001855 complement component C4b binding(GO:0001855)
0.1 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.3 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.1 0.9 GO:0008430 selenium binding(GO:0008430)
0.1 0.3 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.3 GO:0004948 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.4 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.3 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 0.2 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 1.7 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.4 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.6 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 2.0 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.4 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 1.0 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.5 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 1.1 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.0 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 2.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.8 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.6 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 1.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis