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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ONECUT2_ONECUT3

Z-value: 0.80

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Transcription factors associated with ONECUT2_ONECUT3

Gene Symbol Gene ID Gene Info
ENSG00000119547.6 ONECUT2
ENSG00000205922.5 ONECUT3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ONECUT3hg38_v1_chr19_+_1753499_17535210.542.1e-03Click!
ONECUT2hg38_v1_chr18_+_57435366_574353910.346.8e-02Click!

Activity profile of ONECUT2_ONECUT3 motif

Sorted Z-values of ONECUT2_ONECUT3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ONECUT2_ONECUT3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_207165923 2.92 ENST00000309446.11
Kruppel like factor 7
chr7_-_23470469 2.50 ENST00000258729.8
insulin like growth factor 2 mRNA binding protein 3
chr2_-_191151568 2.12 ENST00000358470.8
ENST00000432798.1
ENST00000450994.1
signal transducer and activator of transcription 4
chr8_+_53851786 1.92 ENST00000297313.8
ENST00000344277.10
regulator of G protein signaling 20
chr11_-_124445696 1.91 ENST00000642064.1
olfactory receptor family 8 subfamily B member 8
chrX_+_101550537 1.91 ENST00000372829.8
armadillo repeat containing X-linked 1
chr3_+_159839847 1.63 ENST00000445224.6
schwannomin interacting protein 1
chr8_+_31639755 1.56 ENST00000520407.5
neuregulin 1
chr11_-_107858777 1.56 ENST00000525815.6
solute carrier family 35 member F2
chr8_+_32647080 1.47 ENST00000520502.7
ENST00000523041.2
ENST00000650819.1
neuregulin 1
chr1_-_686673 1.42 ENST00000332831.4
olfactory receptor family 4 subfamily F member 16
chr20_-_22585451 1.38 ENST00000377115.4
forkhead box A2
chr4_-_69961007 1.29 ENST00000353151.3
casein beta
chr5_+_163460650 1.28 ENST00000358715.3
hyaluronan mediated motility receptor
chr7_-_143362687 1.28 ENST00000409578.5
ENST00000443739.7
ENST00000409346.5
family with sequence similarity 131 member B
chr7_+_80602150 1.27 ENST00000309881.11
CD36 molecule
chr3_+_122055355 1.23 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr5_+_163460623 1.22 ENST00000393915.9
ENST00000432118.6
hyaluronan mediated motility receptor
chr19_-_48513161 1.20 ENST00000673139.1
lemur tyrosine kinase 3
chr14_+_36657560 1.16 ENST00000402703.6
paired box 9
chr7_+_80602200 1.08 ENST00000534394.5
CD36 molecule
chr5_+_181367268 1.06 ENST00000456475.1
olfactory receptor family 4 subfamily F member 3
chr8_-_167024 1.04 ENST00000320901.4
olfactory receptor family 4 subfamily F member 21
chr19_+_926001 1.02 ENST00000263620.8
AT-rich interaction domain 3A
chr2_-_55419565 1.02 ENST00000647341.1
ENST00000647401.1
ENST00000336838.10
ENST00000621814.4
ENST00000644033.1
ENST00000645477.1
ENST00000647517.1
coiled-coil domain containing 88A
chr2_+_54558348 0.99 ENST00000333896.5
spectrin beta, non-erythrocytic 1
chr6_+_34236865 0.96 ENST00000674029.1
ENST00000447654.5
ENST00000347617.10
ENST00000401473.7
ENST00000311487.9
high mobility group AT-hook 1
chr10_+_49637400 0.95 ENST00000640822.1
choline O-acetyltransferase
chr3_+_130931893 0.95 ENST00000504612.5
ATPase secretory pathway Ca2+ transporting 1
chr1_-_158554405 0.93 ENST00000641282.1
ENST00000641622.1
olfactory receptor family 6 subfamily Y member 1
chr14_-_23578756 0.93 ENST00000397118.7
ENST00000356300.9
junctophilin 4
chr22_-_35824373 0.86 ENST00000473487.6
RNA binding fox-1 homolog 2
chr15_-_64381431 0.85 ENST00000558008.3
ENST00000300035.9
ENST00000559519.5
ENST00000380258.6
PCNA clamp associated factor
chr1_-_231421146 0.80 ENST00000667629.1
ENST00000670301.1
ENST00000658954.1
egl-9 family hypoxia inducible factor 1
chr5_+_141421020 0.80 ENST00000622044.1
ENST00000398587.7
protocadherin gamma subfamily A, 11
chr12_-_56752366 0.80 ENST00000672280.1
DNA primase subunit 1
chr3_+_63443076 0.79 ENST00000295894.9
synaptoporin
chr9_-_27529705 0.78 ENST00000262244.6
MOB kinase activator 3B
chr1_+_212035717 0.78 ENST00000366991.5
denticleless E3 ubiquitin protein ligase homolog
chr7_-_28180735 0.77 ENST00000283928.10
JAZF zinc finger 1
chr9_+_74615582 0.76 ENST00000396204.2
RAR related orphan receptor B
chr17_-_2401038 0.75 ENST00000174618.5
ENST00000575394.1
MAX network transcriptional repressor
chr3_-_197226351 0.75 ENST00000656428.1
discs large MAGUK scaffold protein 1
chr1_+_207770322 0.74 ENST00000462968.2
CD46 molecule
chr10_-_119536533 0.74 ENST00000392865.5
regulator of G protein signaling 10
chr19_-_4535221 0.74 ENST00000381848.7
ENST00000586133.1
perilipin 5
chr2_-_55419276 0.73 ENST00000646796.1
coiled-coil domain containing 88A
chr14_+_22543179 0.73 ENST00000390534.1
T cell receptor alpha joining 3
chr6_+_130018565 0.67 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr12_-_56752311 0.65 ENST00000338193.11
ENST00000550770.1
DNA primase subunit 1
chr3_-_24165548 0.65 ENST00000280696.9
thyroid hormone receptor beta
chr18_+_44680875 0.63 ENST00000649279.2
ENST00000677699.1
SET binding protein 1
chr5_-_147453888 0.62 ENST00000398514.7
dihydropyrimidinase like 3
chr17_-_43546323 0.62 ENST00000545954.5
ENST00000319349.10
ETS variant transcription factor 4
chrX_-_120559889 0.61 ENST00000371323.3
cullin 4B
chr21_+_38256698 0.61 ENST00000613499.4
ENST00000612702.4
ENST00000398925.5
ENST00000398928.5
ENST00000328656.8
ENST00000443341.5
potassium inwardly rectifying channel subfamily J member 15
chr5_+_127649018 0.61 ENST00000379445.7
cortexin 3
chr17_-_352784 0.60 ENST00000577079.5
ENST00000331302.12
ENST00000618002.4
ENST00000536489.6
rabphilin 3A like (without C2 domains)
chr5_+_139561159 0.57 ENST00000505007.5
ubiquitin conjugating enzyme E2 D2
chrY_-_17880220 0.56 ENST00000382867.4
chromodomain Y-linked 2B
chr1_-_243163310 0.55 ENST00000492145.1
ENST00000490813.5
ENST00000464936.5
centrosomal protein 170
chr19_-_52171643 0.55 ENST00000597065.1
zinc finger protein 836
chr12_+_8992029 0.54 ENST00000543895.1
killer cell lectin like receptor G1
chr1_+_159587817 0.54 ENST00000255040.3
amyloid P component, serum
chr17_-_66229380 0.53 ENST00000205948.11
apolipoprotein H
chr6_-_151452018 0.52 ENST00000491268.2
required for meiotic nuclear division 1 homolog
chrY_-_24047969 0.52 ENST00000306882.4
ENST00000382407.1
chromodomain Y-linked 1B
chr15_+_92900338 0.52 ENST00000625990.3
chromodomain helicase DNA binding protein 2
chr6_-_151452096 0.50 ENST00000444024.3
ENST00000682641.1
ENST00000682299.1
ENST00000622845.5
required for meiotic nuclear division 1 homolog
chr17_-_48614628 0.50 ENST00000576562.1
homeobox B8
chr6_+_99606833 0.49 ENST00000369215.5
PR/SET domain 13
chr20_+_37777262 0.49 ENST00000373469.1
catenin beta like 1
chr7_+_130266847 0.49 ENST00000222481.9
carboxypeptidase A2
chr11_-_102780620 0.48 ENST00000279441.9
ENST00000539681.1
matrix metallopeptidase 10
chr9_-_74952904 0.48 ENST00000376854.6
chromosome 9 open reading frame 40
chr2_-_24328113 0.48 ENST00000622089.4
intersectin 2
chr11_+_126327863 0.47 ENST00000648516.1
decapping enzyme, scavenger
chr3_-_142028597 0.47 ENST00000467667.5
transcription factor Dp-2
chr21_+_38256984 0.46 ENST00000398938.7
potassium inwardly rectifying channel subfamily J member 15
chr9_-_92482350 0.46 ENST00000375543.2
asporin
chr12_-_54259531 0.46 ENST00000550411.5
ENST00000439541.6
chromobox 5
chr3_+_189171948 0.45 ENST00000345063.8
tumor protein p63 regulated 1
chr11_+_8019193 0.43 ENST00000534099.5
TUB bipartite transcription factor
chr19_+_7534004 0.43 ENST00000221249.10
ENST00000601668.5
ENST00000601001.5
patatin like phospholipase domain containing 6
chr9_-_92482499 0.42 ENST00000375544.7
asporin
chr6_+_113857333 0.42 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chrX_-_64976500 0.41 ENST00000447788.6
zinc finger C4H2-type containing
chr1_-_451678 0.39 ENST00000426406.4
olfactory receptor family 4 subfamily F member 29
chr19_-_55738374 0.39 ENST00000590200.1
ENST00000332836.7
NLR family pyrin domain containing 9
chr12_+_101475319 0.39 ENST00000551346.2
Spi-C transcription factor
chr11_-_19060706 0.39 ENST00000329773.3
MAS related GPR family member X2
chr15_+_66386902 0.38 ENST00000307102.10
mitogen-activated protein kinase kinase 1
chr11_+_18132565 0.38 ENST00000621697.2
MAS related GPR family member X3
chr4_-_20984011 0.38 ENST00000382149.9
potassium voltage-gated channel interacting protein 4
chr20_-_63956382 0.37 ENST00000358711.7
ENST00000354216.11
uridine-cytidine kinase 1 like 1
chr14_-_54441325 0.37 ENST00000556113.1
ENST00000553660.5
ENST00000216416.9
ENST00000395573.8
ENST00000557690.5
cornichon family AMPA receptor auxiliary protein 1
chrX_-_64976435 0.36 ENST00000374839.8
zinc finger C4H2-type containing
chr7_-_151633182 0.36 ENST00000476632.2
protein kinase AMP-activated non-catalytic subunit gamma 2
chr3_-_120093666 0.35 ENST00000316626.6
ENST00000650344.2
ENST00000678439.1
glycogen synthase kinase 3 beta
chr12_+_4590075 0.35 ENST00000540757.6
dual specificity tyrosine phosphorylation regulated kinase 4
chr4_+_157220691 0.35 ENST00000509417.5
ENST00000645636.1
ENST00000296526.12
ENST00000264426.14
glutamate ionotropic receptor AMPA type subunit 2
chr1_+_154405193 0.35 ENST00000622330.4
ENST00000344086.8
interleukin 6 receptor
chr19_+_7534242 0.33 ENST00000545201.6
patatin like phospholipase domain containing 6
chr4_+_70050431 0.33 ENST00000511674.5
ENST00000246896.8
histatin 1
chr5_+_141421064 0.33 ENST00000518882.2
protocadherin gamma subfamily A, 11
chr3_-_71581540 0.32 ENST00000650068.1
forkhead box P1
chr4_+_157220654 0.31 ENST00000393815.6
glutamate ionotropic receptor AMPA type subunit 2
chr12_+_80099535 0.31 ENST00000646859.1
ENST00000547103.7
otogelin like
chr3_+_63443306 0.30 ENST00000472899.5
ENST00000479198.5
ENST00000460711.5
ENST00000465156.1
synaptoporin
chr2_-_49974083 0.30 ENST00000636345.1
neurexin 1
chr7_-_13986439 0.29 ENST00000443608.5
ENST00000438956.5
ETS variant transcription factor 1
chr10_+_69801892 0.29 ENST00000398978.8
ENST00000645393.2
ENST00000354547.7
ENST00000674121.1
ENST00000673842.1
ENST00000520267.5
collagen type XIII alpha 1 chain
chr2_-_162536955 0.28 ENST00000621889.1
potassium voltage-gated channel subfamily H member 7
chr12_+_59596010 0.28 ENST00000547379.6
ENST00000552432.5
solute carrier family 16 member 7
chr4_+_70383123 0.28 ENST00000304915.8
submaxillary gland androgen regulated protein 3B
chr20_-_1994046 0.28 ENST00000217305.3
ENST00000650874.1
prodynorphin
chr4_+_70721953 0.27 ENST00000381006.8
ENST00000226328.8
RUN and FYVE domain containing 3
chr10_-_96271553 0.27 ENST00000224337.10
B cell linker
chr10_-_96271508 0.27 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr2_+_33436304 0.27 ENST00000402538.7
RAS guanyl releasing protein 3
chr6_-_75284820 0.27 ENST00000475111.6
transmembrane protein 30A
chr3_+_40100007 0.26 ENST00000539167.2
myosin VIIA and Rab interacting protein
chr16_-_20691256 0.26 ENST00000307493.8
acyl-CoA synthetase medium chain family member 1
chrY_+_25622162 0.25 ENST00000361963.3
ENST00000306609.4
chromodomain Y-linked 1
chr3_-_71583592 0.25 ENST00000650156.1
ENST00000649596.1
forkhead box P1
chr1_+_116754422 0.24 ENST00000369478.4
ENST00000369477.1
CD2 molecule
chr10_+_69802424 0.24 ENST00000673802.2
ENST00000517713.5
ENST00000520133.5
ENST00000522165.5
ENST00000673641.2
ENST00000673628.2
collagen type XIII alpha 1 chain
chr12_+_56752449 0.24 ENST00000554643.5
ENST00000556650.5
ENST00000554150.5
ENST00000554155.1
hydroxysteroid 17-beta dehydrogenase 6
chr2_-_49974182 0.24 ENST00000412315.5
ENST00000378262.7
neurexin 1
chr5_-_9630351 0.24 ENST00000382492.4
taste 2 receptor member 1
chr5_-_156963222 0.24 ENST00000407087.4
ENST00000274532.7
T cell immunoglobulin and mucin domain containing 4
chr16_-_69754913 0.24 ENST00000268802.10
NIN1 (RPN12) binding protein 1 homolog
chr14_+_61697622 0.23 ENST00000539097.2
hypoxia inducible factor 1 subunit alpha
chr17_-_39607876 0.23 ENST00000302584.5
neuronal differentiation 2
chr15_+_92900189 0.23 ENST00000626874.2
ENST00000627622.1
ENST00000629346.2
ENST00000628375.2
ENST00000420239.7
ENST00000394196.9
chromodomain helicase DNA binding protein 2
chrY_+_18025787 0.22 ENST00000250838.6
chromodomain Y-linked 2A
chr4_-_68670648 0.22 ENST00000338206.6
UDP glucuronosyltransferase family 2 member B15
chr5_-_144170607 0.21 ENST00000448443.6
ENST00000513112.5
ENST00000519064.5
ENST00000274496.10
ENST00000522203.5
Yip1 domain family member 5
chr1_-_959240 0.21 ENST00000327044.7
NOC2 like nucleolar associated transcriptional repressor
chr6_+_57090010 0.20 ENST00000510483.5
ENST00000357489.7
zinc finger protein 451
chr4_+_155903688 0.20 ENST00000536354.3
tryptophan 2,3-dioxygenase
chr1_+_92168915 0.20 ENST00000637221.2
BTB domain containing 8
chr2_-_49974155 0.20 ENST00000635519.1
neurexin 1
chr2_-_162838728 0.20 ENST00000328032.8
ENST00000332142.10
potassium voltage-gated channel subfamily H member 7
chr6_+_57090143 0.20 ENST00000508603.5
ENST00000370706.9
ENST00000491832.6
ENST00000370710.10
zinc finger protein 451
chr11_-_116787979 0.20 ENST00000429220.5
ENST00000444935.5
ENST00000227322.8
ZPR1 zinc finger
chr8_+_76681208 0.19 ENST00000651372.2
zinc finger homeobox 4
chr11_-_60855943 0.19 ENST00000332539.5
prostaglandin D2 receptor 2
chr5_+_66144204 0.19 ENST00000612404.4
splicing regulatory glutamic acid and lysine rich protein 1
chr6_+_29100609 0.19 ENST00000377171.3
olfactory receptor family 2 subfamily J member 1
chr3_+_52777580 0.19 ENST00000273283.7
inter-alpha-trypsin inhibitor heavy chain 1
chr17_+_81395469 0.19 ENST00000584436.7
BAH domain and coiled-coil containing 1
chr4_-_101347327 0.19 ENST00000394853.8
protein phosphatase 3 catalytic subunit alpha
chr3_+_109136707 0.18 ENST00000622536.6
chromosome 3 open reading frame 85
chr3_-_187670385 0.18 ENST00000287641.4
somatostatin
chr17_+_81395449 0.18 ENST00000675386.2
BAH domain and coiled-coil containing 1
chr4_+_89879532 0.18 ENST00000394980.5
multimerin 1
chr6_+_27957241 0.18 ENST00000244623.1
olfactory receptor family 2 subfamily B member 6
chr3_-_71583683 0.17 ENST00000649631.1
ENST00000648718.1
forkhead box P1
chr19_-_44448435 0.17 ENST00000588655.1
ENST00000592308.1
ENST00000614049.5
ENST00000613197.4
novel transcript
zinc finger protein 229
chr3_-_186362223 0.17 ENST00000265022.8
diacylglycerol kinase gamma
chr12_+_48472559 0.16 ENST00000266594.4
acidic nuclear phosphoprotein 32 family member D
chr1_-_159714581 0.16 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
C-reactive protein
chr4_-_101347492 0.16 ENST00000394854.8
protein phosphatase 3 catalytic subunit alpha
chr5_-_136365476 0.16 ENST00000378459.7
ENST00000502753.4
ENST00000513104.6
ENST00000352189.8
transient receptor potential cation channel subfamily C member 7
chr1_+_192636121 0.16 ENST00000543215.5
ENST00000391995.7
regulator of G protein signaling 13
chr16_+_7303245 0.16 ENST00000674626.1
RNA binding fox-1 homolog 1
chrX_+_91434829 0.15 ENST00000312600.4
poly(A) binding protein cytoplasmic 5
chr2_+_6877768 0.15 ENST00000382040.4
radical S-adenosyl methionine domain containing 2
chr11_-_790062 0.15 ENST00000330106.5
cell cycle exit and neuronal differentiation 1
chr3_+_69936629 0.15 ENST00000394348.2
ENST00000531774.1
melanocyte inducing transcription factor
chr16_-_49856105 0.15 ENST00000563137.7
zinc finger protein 423
chr16_-_1963100 0.15 ENST00000526586.6
ribosomal protein S2
chr17_-_4263847 0.15 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ankyrin repeat and FYVE domain containing 1
chr16_-_66918839 0.14 ENST00000565235.2
ENST00000568632.5
ENST00000565796.5
cadherin 16
chr12_+_100200779 0.14 ENST00000188312.7
ENST00000546902.5
ENST00000552376.5
ENST00000551617.1
actin related protein 6
chr4_-_101347471 0.14 ENST00000323055.10
ENST00000512215.5
protein phosphatase 3 catalytic subunit alpha
chr1_-_115841116 0.14 ENST00000320238.3
nescient helix-loop-helix 2
chr7_+_129368123 0.14 ENST00000460109.5
ENST00000474594.5
adenosylhomocysteinase like 2
chr7_+_99828010 0.14 ENST00000631161.2
ENST00000354829.7
ENST00000342499.8
ENST00000417625.5
ENST00000415413.5
ENST00000444905.5
ENST00000222382.5
ENST00000312017.9
cytochrome P450 family 3 subfamily A member 43
chr7_-_126533850 0.14 ENST00000444921.3
glutamate metabotropic receptor 8
chr9_-_28670285 0.14 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
leucine rich repeat and Ig domain containing 2
chr5_+_148394712 0.14 ENST00000513826.1
F-box protein 38
chr4_+_186266183 0.14 ENST00000403665.7
ENST00000492972.6
ENST00000264692.8
coagulation factor XI
chr5_+_139561308 0.14 ENST00000398733.8
ubiquitin conjugating enzyme E2 D2
chr12_+_32679269 0.13 ENST00000358214.9
ENST00000553257.6
ENST00000549701.6
ENST00000266481.10
ENST00000551476.5
ENST00000550154.5
ENST00000547312.5
ENST00000381000.8
ENST00000548750.5
dynamin 1 like
chr4_-_101346842 0.13 ENST00000507176.5
protein phosphatase 3 catalytic subunit alpha
chr16_-_66918876 0.13 ENST00000570262.5
ENST00000299752.9
ENST00000394055.7
cadherin 16
chr1_-_110607425 0.13 ENST00000633222.1
potassium voltage-gated channel subfamily A member 2
chr3_-_142028617 0.13 ENST00000477292.5
ENST00000478006.5
ENST00000495310.5
ENST00000486111.5
transcription factor Dp-2
chr7_-_13986498 0.12 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETS variant transcription factor 1
chr19_+_45093140 0.12 ENST00000544069.2
ENST00000221462.9
protein phosphatase 1 regulatory subunit 37
chr12_-_62192762 0.12 ENST00000416284.8
TAFA chemokine like family member 2
chr2_+_67397297 0.12 ENST00000644028.1
ENST00000272342.6
ETAA1 activator of ATR kinase
chr9_+_100578071 0.11 ENST00000307584.6
caveolae associated protein 4
chr1_-_110607307 0.11 ENST00000639048.2
ENST00000675391.1
ENST00000639233.2
potassium voltage-gated channel subfamily A member 2
chr3_-_71583713 0.11 ENST00000649528.3
ENST00000471386.3
ENST00000493089.7
forkhead box P1
chr12_+_20695323 0.10 ENST00000266509.7
solute carrier organic anion transporter family member 1C1
chr12_-_91153149 0.10 ENST00000550758.1
decorin
chr7_+_120273129 0.10 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.4 1.3 GO:1903487 regulation of lactation(GO:1903487)
0.4 1.2 GO:0043017 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.3 1.7 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.3 2.3 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 1.0 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 3.0 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.2 1.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 0.8 GO:0030821 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.2 1.0 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.2 0.5 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.2 0.9 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 0.5 GO:0036245 cellular response to menadione(GO:0036245)
0.2 0.6 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.7 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.9 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.7 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.4 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339) negative regulation of type B pancreatic cell development(GO:2000077)
0.1 0.5 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.3 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.9 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 1.0 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 0.7 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.1 2.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.2 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.1 0.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.8 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.4 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.2 GO:0090149 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
0.0 0.8 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.7 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.4 GO:0044211 CTP salvage(GO:0044211)
0.0 0.4 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 1.2 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.3 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 1.0 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 1.0 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.2 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.1 GO:0021763 subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.2 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 5.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.7 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.2 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885) positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.5 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 1.6 GO:0019985 translesion synthesis(GO:0019985)
0.0 1.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.8 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 2.0 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0032439 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 2.4 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.8 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 1.6 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.5 GO:0007625 grooming behavior(GO:0007625)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.7 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.1 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.0 2.7 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.0 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 1.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 0.5 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 1.0 GO:0032437 cuticular plate(GO:0032437)
0.1 0.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 1.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.7 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 1.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.9 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.2 GO:0030689 Noc complex(GO:0030689)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 3.1 GO:0030673 axolemma(GO:0030673)
0.1 2.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.4 GO:0033010 paranodal junction(GO:0033010)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 1.5 GO:0003896 DNA primase activity(GO:0003896)
0.2 1.0 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.2 3.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.3 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.7 GO:0035473 lipase binding(GO:0035473)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.7 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.9 GO:0005549 odorant binding(GO:0005549)
0.1 0.2 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 2.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.8 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.7 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.8 GO:0033130 acetylcholine receptor binding(GO:0033130) neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 1.0 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 3.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 1.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 4.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.8 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 3.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.0 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 5.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 2.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.7 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.5 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators