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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for OVOL1

Z-value: 0.34

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Transcription factors associated with OVOL1

Gene Symbol Gene ID Gene Info
OVOL1
ENSG00000172818.10 OVOL1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OVOL1hg38_v1_chr11_+_65787056_65787075-0.222.5e-01Click!

Activity profile of OVOL1 motif

Sorted Z-values of OVOL1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of OVOL1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_16508788 1.04 ENST00000682142.1
RETREG1
reticulophagy regulator 1
chr5_-_16508990 1.01 ENST00000399793.6
RETREG1
reticulophagy regulator 1
chr5_+_140882116 0.64 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
PCDHA13
protocadherin alpha 13
chr11_+_123430259 0.64 ENST00000533341.3
ENST00000635736.2
GRAMD1B
GRAM domain containing 1B
chr5_-_16508858 0.50 ENST00000684456.1
RETREG1
reticulophagy regulator 1
chr5_-_16508951 0.48 ENST00000682628.1
RETREG1
reticulophagy regulator 1
chr5_-_16508812 0.47 ENST00000683414.1
RETREG1
reticulophagy regulator 1
chrX_-_117973717 0.45 ENST00000262820.7
KLHL13
kelch like family member 13
chrX_-_117973579 0.42 ENST00000371878.5
KLHL13
kelch like family member 13
chr3_-_165837412 0.36 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
BCHE
butyrylcholinesterase
chr11_-_75306688 0.33 ENST00000532525.1
ARRB1
arrestin beta 1
chr2_-_152099155 0.27 ENST00000637309.1
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr2_-_152099023 0.24 ENST00000201943.10
ENST00000427385.6
ENST00000539935.7
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr19_+_6772699 0.23 ENST00000602142.6
ENST00000304076.6
ENST00000596764.5
VAV1
vav guanine nucleotide exchange factor 1
chr1_+_174877430 0.15 ENST00000392064.6
RABGAP1L
RAB GTPase activating protein 1 like
chr4_+_75556048 0.15 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
ODAPH
odontogenesis associated phosphoprotein
chr4_-_67754335 0.15 ENST00000420975.2
ENST00000226413.5
GNRHR
gonadotropin releasing hormone receptor
chr10_-_72088533 0.15 ENST00000373109.7
SPOCK2
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr10_-_72088972 0.11 ENST00000317376.8
ENST00000412663.5
SPOCK2
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr12_-_56741535 0.09 ENST00000647707.1
ENSG00000285625.1
novel protein
chr15_-_64093746 0.09 ENST00000557835.5
ENST00000380290.7
ENST00000300030.8
ENST00000559950.1
CIAO2A
cytosolic iron-sulfur assembly component 2A
chr2_-_37672178 0.08 ENST00000457889.1
CDC42EP3
CDC42 effector protein 3
chr17_-_7242156 0.08 ENST00000571129.5
ENST00000571253.1
ENST00000573928.1
ENST00000302386.10
GABARAP
GABA type A receptor-associated protein
chr19_+_37371152 0.08 ENST00000483919.5
ENST00000588911.5
ENST00000587349.1
ZNF527
zinc finger protein 527
chr11_+_71999927 0.05 ENST00000393707.4
IL18BP
interleukin 18 binding protein
chr6_-_83709382 0.02 ENST00000520302.5
ENST00000520213.5
ENST00000439399.6
SNAP91
synaptosome associated protein 91
chr15_+_75043263 0.02 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr20_+_56248732 0.01 ENST00000243911.2
MC3R
melanocortin 3 receptor
chr10_+_47322450 0.01 ENST00000581492.3
GDF2
growth differentiation factor 2
chr19_-_49442360 0.00 ENST00000600601.5
SLC17A7
solute carrier family 17 member 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.5 GO:0061709 reticulophagy(GO:0061709)
0.1 0.4 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.4 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.0 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors