ISMARA results: PAX3

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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PAX3

Z-value: 0.53

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Transcription factors associated with PAX3

Gene Symbol	Gene ID	Gene Info
PAX3 Ensembl NCBI GeneCards UniProt	ENSG00000135903.20	PAX3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
PAX3	hg38_v1_chr2_-_222298659_222298690	0.49	6.2e-03	Click!

Activity profile of PAX3 motif

Sorted Z-values of PAX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX3

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr9_+_33795551 Show fit	1.81	ENST00000379405.4	PRSS3 Ensembl NCBI GeneCards UniProt Show fit	serine protease 3
chr15_-_79971164 Show fit	1.37	ENST00000335661.6 ENST00000267953.4 ENST00000677151.1	BCL2A1 Ensembl NCBI GeneCards UniProt Show fit	BCL2 related protein A1
chr15_+_45430579 Show fit	1.29	ENST00000558435.5 ENST00000344300.3 ENST00000396650.7	C15orf48 Ensembl NCBI GeneCards UniProt Show fit	chromosome 15 open reading frame 48
chr7_+_142770960 Show fit	1.19	ENST00000632805.1 ENST00000633969.1 ENST00000539842.6	PRSS2 Ensembl NCBI GeneCards UniProt Show fit	serine protease 2
chr4_-_103198331 Show fit	1.18	ENST00000265148.9 ENST00000514974.1	CENPE Ensembl NCBI GeneCards UniProt Show fit	centromere protein E
chrX_+_38561530 Show fit	1.06	ENST00000378482.7 ENST00000286824.6	TSPAN7 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 7
chr4_-_103198371 Show fit	0.95	ENST00000611174.4 ENST00000380026.8	CENPE Ensembl NCBI GeneCards UniProt Show fit	centromere protein E
chrX_+_136148440 Show fit	0.87	ENST00000627383.2 ENST00000630084.2	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr19_-_2783308 Show fit	0.86	ENST00000677562.1 ENST00000677754.1	SGTA Ensembl NCBI GeneCards UniProt Show fit	small glutamine rich tetratricopeptide repeat containing alpha
chr19_-_2783241 Show fit	0.80	ENST00000676943.1 ENST00000589251.5 ENST00000221566.7 ENST00000676984.1	SGTA Ensembl NCBI GeneCards UniProt Show fit	small glutamine rich tetratricopeptide repeat containing alpha
chr4_+_155758990 Show fit	0.75	ENST00000505154.5 ENST00000652626.1 ENST00000502959.5 ENST00000264424.13 ENST00000505764.5 ENST00000507146.5 ENST00000503520.5	GUCY1B1 Ensembl NCBI GeneCards UniProt Show fit	guanylate cyclase 1 soluble subunit beta 1
chr10_-_124450027 Show fit	0.73	ENST00000451024.5	NKX1-2 Ensembl NCBI GeneCards UniProt Show fit	NK1 homeobox 2
chr13_-_60013178 Show fit	0.66	ENST00000498416.2 ENST00000465066.5	DIAPH3 Ensembl NCBI GeneCards UniProt Show fit	diaphanous related formin 3
chr3_+_160399630 Show fit	0.61	ENST00000465903.5 ENST00000485645.5 ENST00000472991.5 ENST00000467468.5 ENST00000469762.5 ENST00000357388.8 ENST00000489573.5 ENST00000462787.5 ENST00000490207.5 ENST00000485867.5	SMC4 Ensembl NCBI GeneCards UniProt Show fit	structural maintenance of chromosomes 4
chrX_-_104076194 Show fit	0.56	ENST00000620307.4 ENST00000598087.3	TMSB15B Ensembl NCBI GeneCards UniProt Show fit	thymosin beta 15B
chr17_-_40417873 Show fit	0.54	ENST00000423485.6	TOP2A Ensembl NCBI GeneCards UniProt Show fit	DNA topoisomerase II alpha
chr7_+_107660819 Show fit	0.54	ENST00000644269.2	SLC26A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 26 member 4
chr7_-_30026617 Show fit	0.54	ENST00000222803.10	FKBP14 Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 14
chr20_-_25585517 Show fit	0.53	ENST00000422516.5 ENST00000278886.11	NINL Ensembl NCBI GeneCards UniProt Show fit	ninein like
chr1_+_84164370 Show fit	0.53	ENST00000446538.5 ENST00000610703.4 ENST00000370682.7 ENST00000394838.6 ENST00000432111.5	PRKACB Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-activated catalytic subunit beta
chr19_-_47545261 Show fit	0.52	ENST00000595558.1 ENST00000263351.9	ZNF541 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 541
chr7_-_148883474 Show fit	0.46	ENST00000476773.5	EZH2 Ensembl NCBI GeneCards UniProt Show fit	enhancer of zeste 2 polycomb repressive complex 2 subunit
chr9_-_112175185 Show fit	0.45	ENST00000355396.7	SUSD1 Ensembl NCBI GeneCards UniProt Show fit	sushi domain containing 1
chr7_+_142384328 Show fit	0.45	ENST00000390361.3	TRBV7-3 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 7-3
chr14_+_20469399 Show fit	0.44	ENST00000361505.10 ENST00000553591.1	PNP Ensembl NCBI GeneCards UniProt Show fit	purine nucleoside phosphorylase
chr19_-_7021431 Show fit	0.44	ENST00000636986.2 ENST00000637800.1	MBD3L2B Ensembl NCBI GeneCards UniProt Show fit	methyl-CpG binding domain protein 3 like 2B
chr14_+_21042352 Show fit	0.44	ENST00000298690.5	RNASE7 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease A family member 7
chr4_+_8580387 Show fit	0.44	ENST00000382487.5	GPR78 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 78
chr19_+_55339867 Show fit	0.43	ENST00000255613.8	KMT5C Ensembl NCBI GeneCards UniProt Show fit	lysine methyltransferase 5C
chr1_+_6034980 Show fit	0.42	ENST00000378092.6 ENST00000472700.7	KCNAB2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr7_+_142749465 Show fit	0.40	ENST00000486171.5 ENST00000619214.4 ENST00000311737.12	PRSS1 Ensembl NCBI GeneCards UniProt Show fit	serine protease 1
chr14_-_100375333 Show fit	0.40	ENST00000557297.5 ENST00000555813.5 ENST00000392882.7 ENST00000557135.5 ENST00000556698.5 ENST00000554509.5 ENST00000555410.5	WARS1 Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl-tRNA synthetase 1
chr6_+_163414637 Show fit	0.39	ENST00000453779.6 ENST00000275262.11 ENST00000392127.6	QKI Ensembl NCBI GeneCards UniProt Show fit	QKI, KH domain containing RNA binding
chr21_-_37267511 Show fit	0.38	ENST00000398998.1	VPS26C Ensembl NCBI GeneCards UniProt Show fit	VPS26 endosomal protein sorting factor C
chr6_-_37258110 Show fit	0.38	ENST00000357219.4 ENST00000652386.1 ENST00000652639.1	TMEM217 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 217
chrX_+_43656289 Show fit	0.37	ENST00000338702.4	MAOA Ensembl NCBI GeneCards UniProt Show fit	monoamine oxidase A
chr22_+_20117734 Show fit	0.37	ENST00000416427.5 ENST00000421656.5 ENST00000423859.5 ENST00000418705.2	RANBP1 Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 1
chr14_-_59465327 Show fit	0.37	ENST00000395116.1	GPR135 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 135
chr3_+_50155305 Show fit	0.36	ENST00000002829.8 ENST00000426511.5	SEMA3F Ensembl NCBI GeneCards UniProt Show fit	semaphorin 3F
chr11_+_31369834 Show fit	0.36	ENST00000465995.6	DNAJC24 Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C24
chrX_-_15854791 Show fit	0.35	ENST00000545766.7 ENST00000380291.5 ENST00000672987.1 ENST00000329235.6	AP1S2 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 1 subunit sigma 2
chrX_-_53434341 Show fit	0.34	ENST00000375298.4 ENST00000375304.9 ENST00000684692.1 ENST00000168216.11	HSD17B10 Ensembl NCBI GeneCards UniProt Show fit	hydroxysteroid 17-beta dehydrogenase 10
chr2_+_44361897 Show fit	0.33	ENST00000378494.8 ENST00000402247.5 ENST00000407131.5 ENST00000403853.7	CAMKMT Ensembl NCBI GeneCards UniProt Show fit	calmodulin-lysine N-methyltransferase
chr21_-_37267300 Show fit	0.33	ENST00000309117.11 ENST00000476950.5 ENST00000399001.5	VPS26C Ensembl NCBI GeneCards UniProt Show fit	VPS26 endosomal protein sorting factor C
chr14_-_64338096 Show fit	0.32	ENST00000554572.5 ENST00000358599.9	ESR2 Ensembl NCBI GeneCards UniProt Show fit	estrogen receptor 2
chr19_+_11541125 Show fit	0.31	ENST00000587087.5	CNN1 Ensembl NCBI GeneCards UniProt Show fit	calponin 1
chr9_-_111759508 Show fit	0.30	ENST00000394777.8 ENST00000394779.7	SHOC1 Ensembl NCBI GeneCards UniProt Show fit	shortage in chiasmata 1
chr22_-_21227637 Show fit	0.29	ENST00000401924.5	GGT2 Ensembl NCBI GeneCards UniProt Show fit	gamma-glutamyltransferase 2
chr14_+_51847145 Show fit	0.28	ENST00000615906.4	GNG2 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit gamma 2
chr3_-_51779187 Show fit	0.28	ENST00000398780.5 ENST00000668964.1 ENST00000667863.2 ENST00000647442.1	IQCF6 Ensembl NCBI GeneCards UniProt Show fit	IQ motif containing F6
chr1_-_153150884 Show fit	0.28	ENST00000368748.5	SPRR2G Ensembl NCBI GeneCards UniProt Show fit	small proline rich protein 2G
chr13_+_97953652 Show fit	0.27	ENST00000460070.6 ENST00000481455.6 ENST00000261574.10 ENST00000651721.2 ENST00000493281.6 ENST00000463157.6 ENST00000471898.5 ENST00000489058.6 ENST00000481689.6	IPO5 Ensembl NCBI GeneCards UniProt Show fit	importin 5
chr13_+_31739520 Show fit	0.26	ENST00000298386.7	RXFP2 Ensembl NCBI GeneCards UniProt Show fit	relaxin family peptide receptor 2
chr17_-_8156320 Show fit	0.26	ENST00000584202.1 ENST00000354903.9 ENST00000577253.5	PER1 Ensembl NCBI GeneCards UniProt Show fit	period circadian regulator 1
chr12_+_68686951 Show fit	0.25	ENST00000378905.6 ENST00000229179.9	NUP107 Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 107
chr10_-_124744254 Show fit	0.25	ENST00000280780.6	FAM53B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 53 member B
chr6_+_29111560 Show fit	0.24	ENST00000377169.2	OR2J3 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily J member 3
chr3_+_14675128 Show fit	0.24	ENST00000435614.5 ENST00000253697.8 ENST00000412910.1	C3orf20 Ensembl NCBI GeneCards UniProt Show fit	chromosome 3 open reading frame 20
chr7_+_142598016 Show fit	0.24	ENST00000620773.1	TRBV16 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 16
chr6_+_29173303 Show fit	0.24	ENST00000377167.3	OR2J2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily J member 2
chr11_+_112167366 Show fit	0.23	ENST00000530752.5 ENST00000280358.5	TEX12 Ensembl NCBI GeneCards UniProt Show fit	testis expressed 12
chr5_+_148268741 Show fit	0.23	ENST00000398450.5	SPINK13 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor Kazal type 13
chr1_+_100719734 Show fit	0.23	ENST00000370119.8 ENST00000294728.7 ENST00000347652.6 ENST00000370115.1	VCAM1 Ensembl NCBI GeneCards UniProt Show fit	vascular cell adhesion molecule 1
chr17_+_37375974 Show fit	0.23	ENST00000615133.2 ENST00000611038.4	C17orf78 Ensembl NCBI GeneCards UniProt Show fit	chromosome 17 open reading frame 78
chr12_+_112125531 Show fit	0.22	ENST00000549358.5 ENST00000257604.9 ENST00000548092.5 ENST00000412615.7 ENST00000552896.1	TRAFD1 Ensembl NCBI GeneCards UniProt Show fit	TRAF-type zinc finger domain containing 1
chr9_+_128787243 Show fit	0.22	ENST00000372648.10	TBC1D13 Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 13
chr14_+_22495890 Show fit	0.22	ENST00000390494.1	TRAJ43 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha joining 43
chr4_-_167234552 Show fit	0.22	ENST00000512648.5	SPOCK3 Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr7_+_128758947 Show fit	0.21	ENST00000493278.1	CALU Ensembl NCBI GeneCards UniProt Show fit	calumenin
chr12_-_10409757 Show fit	0.21	ENST00000309384.2	KLRC4 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor C4
chr3_+_111911604 Show fit	0.21	ENST00000495180.1	PHLDB2 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology like domain family B member 2
chr7_-_142962206 Show fit	0.20	ENST00000460479.2 ENST00000476829.5 ENST00000355265.7	KEL Ensembl NCBI GeneCards UniProt Show fit	Kell metallo-endopeptidase (Kell blood group)
chr17_-_69150062 Show fit	0.20	ENST00000522787.5 ENST00000521538.5	ABCA10 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily A member 10
chr6_+_31971831 Show fit	0.20	ENST00000375331.7 ENST00000375333.3	STK19 Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 19
chr11_+_313391 Show fit	0.19	ENST00000680802.1 ENST00000528780.5 ENST00000681761.1 ENST00000681821.1 ENST00000328221.5	IFITM1 Ensembl NCBI GeneCards UniProt Show fit	interferon induced transmembrane protein 1
chr19_-_4831689 Show fit	0.19	ENST00000248244.6	TICAM1 Ensembl NCBI GeneCards UniProt Show fit	toll like receptor adaptor molecule 1
chr8_-_10655137 Show fit	0.19	ENST00000382483.4	RP1L1 Ensembl NCBI GeneCards UniProt Show fit	RP1 like 1
chr6_+_108295037 Show fit	0.19	ENST00000368977.9 ENST00000421954.5	AFG1L Ensembl NCBI GeneCards UniProt Show fit	AFG1 like ATPase
chr17_+_4951758 Show fit	0.19	ENST00000518175.1	ENO3 Ensembl NCBI GeneCards UniProt Show fit	enolase 3
chr9_-_21368962 Show fit	0.19	ENST00000610660.1	IFNA13 Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 13
chr16_+_29790715 Show fit	0.18	ENST00000561482.5 ENST00000569636.6 ENST00000160827.9	KIF22 Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 22
chrX_-_49073989 Show fit	0.18	ENST00000376386.3 ENST00000553851.3	PRAF2 Ensembl NCBI GeneCards UniProt Show fit	PRA1 domain family member 2
chr3_+_112990956 Show fit	0.18	ENST00000383678.8 ENST00000383677.7 ENST00000619116.4	GTPBP8 Ensembl NCBI GeneCards UniProt Show fit	GTP binding protein 8 (putative)
chr1_+_40040219 Show fit	0.18	ENST00000372797.7 ENST00000372802.5 ENST00000449311.5	CAP1 Ensembl NCBI GeneCards UniProt Show fit	cyclase associated actin cytoskeleton regulatory protein 1
chr6_+_163414701 Show fit	0.17	ENST00000361752.8	QKI Ensembl NCBI GeneCards UniProt Show fit	QKI, KH domain containing RNA binding
chr4_+_73409340 Show fit	0.17	ENST00000511370.1	ALB Ensembl NCBI GeneCards UniProt Show fit	albumin
chr3_+_49689531 Show fit	0.17	ENST00000432042.5 ENST00000454491.5 ENST00000327697.11	RNF123 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 123
chr5_-_157652432 Show fit	0.17	ENST00000265007.11	SOX30 Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 30
chr1_-_153958576 Show fit	0.17	ENST00000368630.7 ENST00000368633.2	CRTC2 Ensembl NCBI GeneCards UniProt Show fit	CREB regulated transcription coactivator 2
chr6_-_137173644 Show fit	0.17	ENST00000296980.7 ENST00000349184.8 ENST00000339602.3	IL22RA2 Ensembl NCBI GeneCards UniProt Show fit	interleukin 22 receptor subunit alpha 2
chr9_-_70414657 Show fit	0.17	ENST00000377126.4	KLF9 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 9
chr10_+_94402486 Show fit	0.17	ENST00000225235.5	TBC1D12 Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 12
chr6_-_5260883 Show fit	0.17	ENST00000330636.9	LYRM4 Ensembl NCBI GeneCards UniProt Show fit	LYR motif containing 4
chr12_+_10307950 Show fit	0.17	ENST00000543420.5 ENST00000543777.5	KLRD1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor D1
chr17_+_39200302 Show fit	0.17	ENST00000579374.5	RPL19 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L19
chr2_-_216860042 Show fit	0.17	ENST00000236979.2	TNP1 Ensembl NCBI GeneCards UniProt Show fit	transition protein 1
chr1_+_12464912 Show fit	0.17	ENST00000543766.2	VPS13D Ensembl NCBI GeneCards UniProt Show fit	vacuolar protein sorting 13 homolog D
chr19_-_34677157 Show fit	0.16	ENST00000601241.6	SCGB2B2 Ensembl NCBI GeneCards UniProt Show fit	secretoglobin family 2B member 2
chr1_-_26890237 Show fit	0.16	ENST00000431781.2 ENST00000374135.9	GPN2 Ensembl NCBI GeneCards UniProt Show fit	GPN-loop GTPase 2
chr9_+_128787331 Show fit	0.16	ENST00000223865.8	TBC1D13 Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 13
chr17_+_39200334 Show fit	0.16	ENST00000579260.5 ENST00000582193.5	RPL19 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L19
chr7_+_142492121 Show fit	0.16	ENST00000390374.3	TRBV7-6 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 7-6
chr15_+_99251362 Show fit	0.16	ENST00000558879.5 ENST00000301981.8 ENST00000447360.6 ENST00000558172.5 ENST00000561276.5 ENST00000331450.9	LRRC28 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 28
chr17_-_75154503 Show fit	0.16	ENST00000409753.8 ENST00000581874.1	JPT1 Ensembl NCBI GeneCards UniProt Show fit	Jupiter microtubule associated homolog 1
chr7_-_151633182 Show fit	0.16	ENST00000476632.2	PRKAG2 Ensembl NCBI GeneCards UniProt Show fit	protein kinase AMP-activated non-catalytic subunit gamma 2
chr17_+_39200275 Show fit	0.15	ENST00000225430.9	RPL19 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L19
chr3_-_52239082 Show fit	0.15	ENST00000499914.2 ENST00000678838.1 ENST00000305533.10 ENST00000678330.1	TWF2 Ensembl NCBI GeneCards UniProt Show fit	twinfilin actin binding protein 2
chrX_+_154542194 Show fit	0.15	ENST00000618670.4	IKBKG Ensembl NCBI GeneCards UniProt Show fit	inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chr3_+_184174846 Show fit	0.15	ENST00000427072.5 ENST00000411763.6 ENST00000292807.9 ENST00000448139.5 ENST00000455925.1	AP2M1 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 2 subunit mu 1
chr2_+_233718734 Show fit	0.15	ENST00000373409.8	UGT1A4 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A4
chr2_-_88979016 Show fit	0.15	ENST00000390247.2	IGKV3-7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-7 (non-functional)
chrY_-_6911752 Show fit	0.15	ENST00000651267.2	AMELY Ensembl NCBI GeneCards UniProt Show fit	amelogenin Y-linked
chr3_+_184300564 Show fit	0.14	ENST00000435761.5 ENST00000439383.5	PSMD2 Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, non-ATPase 2
chr6_+_14117764 Show fit	0.14	ENST00000379153.4	CD83 Ensembl NCBI GeneCards UniProt Show fit	CD83 molecule
chr7_-_151877105 Show fit	0.14	ENST00000287878.9 ENST00000652321.1	PRKAG2 Ensembl NCBI GeneCards UniProt Show fit	protein kinase AMP-activated non-catalytic subunit gamma 2
chr11_-_14643617 Show fit	0.14	ENST00000418988.2	PSMA1 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 1
chr19_-_41959266 Show fit	0.13	ENST00000600292.5 ENST00000601078.5 ENST00000601891.5 ENST00000222008.11	RABAC1 Ensembl NCBI GeneCards UniProt Show fit	Rab acceptor 1
chr1_+_206897435 Show fit	0.13	ENST00000391929.7 ENST00000294984.7 ENST00000611909.4 ENST00000367093.3	IL24 Ensembl NCBI GeneCards UniProt Show fit	interleukin 24
chr9_-_21217311 Show fit	0.12	ENST00000380216.1	IFNA16 Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 16
chr5_+_148268830 Show fit	0.12	ENST00000511106.5	SPINK13 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor Kazal type 13
chr18_+_61333424 Show fit	0.12	ENST00000262717.9	CDH20 Ensembl NCBI GeneCards UniProt Show fit	cadherin 20
chr4_+_112145445 Show fit	0.11	ENST00000309733.6	FAM241A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 241 member A
chr12_+_10307818 Show fit	0.11	ENST00000350274.9 ENST00000336164.9	KLRD1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor D1
chr1_-_101025763 Show fit	0.11	ENST00000342173.11 ENST00000488176.1 ENST00000370109.8	DPH5 Ensembl NCBI GeneCards UniProt Show fit	diphthamide biosynthesis 5
chr17_-_3557798 Show fit	0.11	ENST00000301365.8 ENST00000572519.1 ENST00000576742.6	TRPV3 Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily V member 3
chr20_-_17531366 Show fit	0.11	ENST00000377873.8	BFSP1 Ensembl NCBI GeneCards UniProt Show fit	beaded filament structural protein 1
chr14_+_21749163 Show fit	0.11	ENST00000390427.3	TRAV5 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 5
chrX_+_47218232 Show fit	0.11	ENST00000457458.6 ENST00000522883.1	CDK16 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 16
chr8_-_70071226 Show fit	0.10	ENST00000276594.3	PRDM14 Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 14
chr9_-_97922487 Show fit	0.10	ENST00000455506.1 ENST00000375117.8 ENST00000375119.8 ENST00000611338.4	TRMO Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase O
chrX_+_71144818 Show fit	0.10	ENST00000536169.5 ENST00000358741.4 ENST00000395855.6 ENST00000374051.7	NLGN3 Ensembl NCBI GeneCards UniProt Show fit	neuroligin 3
chr9_-_13175824 Show fit	0.09	ENST00000545857.5	MPDZ Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain crumbs cell polarity complex component
chr22_-_43862480 Show fit	0.09	ENST00000330884.9	SULT4A1 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family 4A member 1
chr7_-_19773569 Show fit	0.09	ENST00000422233.5 ENST00000433641.5 ENST00000405844.6	TMEM196 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 196
chr12_+_8157034 Show fit	0.08	ENST00000396570.7	ZNF705A Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 705A
chr5_+_70049638 Show fit	0.08	ENST00000511812.5 ENST00000626847.2 ENST00000380742.8 ENST00000380743.9 ENST00000638794.1 ENST00000628696.2 ENST00000614240.4 ENST00000380741.8	SMN2 Ensembl NCBI GeneCards UniProt Show fit	survival of motor neuron 2, centromeric
chr15_-_78077657 Show fit	0.08	ENST00000300584.8 ENST00000409931.7	TBC1D2B Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 2B
chr5_+_70925030 Show fit	0.08	ENST00000503079.6 ENST00000514951.5 ENST00000380707.9 ENST00000506163.5 ENST00000625245.2 ENST00000351205.8	SMN1 Ensembl NCBI GeneCards UniProt Show fit	survival of motor neuron 1, telomeric
chr12_+_10010627 Show fit	0.08	ENST00000338896.11 ENST00000396502.5	CLEC12B Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 12 member B
chr17_-_7931910 Show fit	0.08	ENST00000303731.9 ENST00000571947.5 ENST00000540486.5 ENST00000572656.2	TRAPPC1 Ensembl NCBI GeneCards UniProt Show fit	trafficking protein particle complex 1
chr1_-_13198130 Show fit	0.08	ENST00000638454.1	PRAMEF13 Ensembl NCBI GeneCards UniProt Show fit	PRAME family member 13
chr3_+_133573637 Show fit	0.08	ENST00000264993.8	CDV3 Ensembl NCBI GeneCards UniProt Show fit	CDV3 homolog
chr11_-_615921 Show fit	0.08	ENST00000348655.11 ENST00000525445.6 ENST00000330243.9	IRF7 Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 7
chr2_+_167868948 Show fit	0.08	ENST00000392690.3	B3GALT1 Ensembl NCBI GeneCards UniProt Show fit	beta-1,3-galactosyltransferase 1
chr2_-_113756604 Show fit	0.07	ENST00000409342.1	SLC35F5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 35 member F5
chr1_-_23825402 Show fit	0.07	ENST00000235958.4 ENST00000436439.6 ENST00000374490.8	HMGCL Ensembl NCBI GeneCards UniProt Show fit	3-hydroxy-3-methylglutaryl-CoA lyase
chr2_+_151357583 Show fit	0.07	ENST00000243347.5	TNFAIP6 Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 6
chr2_-_217842154 Show fit	0.07	ENST00000446688.5	TNS1 Ensembl NCBI GeneCards UniProt Show fit	tensin 1
chr4_-_140568958 Show fit	0.07	ENST00000262999.4	UCP1 Ensembl NCBI GeneCards UniProt Show fit	uncoupling protein 1
chr19_+_37594867 Show fit	0.07	ENST00000316433.9 ENST00000590588.5 ENST00000586134.5 ENST00000586792.5	ZNF540 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 540
chr14_+_22207502 Show fit	0.07	ENST00000390461.2	TRAV34 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 34
chr4_+_15374541 Show fit	0.07	ENST00000382383.7 ENST00000429690.5	C1QTNF7 Ensembl NCBI GeneCards UniProt Show fit	C1q and TNF related 7
chr15_-_52191387 Show fit	0.07	ENST00000261837.12	GNB5 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit beta 5
chr22_+_38705922 Show fit	0.07	ENST00000216044.10	GTPBP1 Ensembl NCBI GeneCards UniProt Show fit	GTP binding protein 1
chr17_-_41382298 Show fit	0.06	ENST00000394001.3	KRT34 Ensembl NCBI GeneCards UniProt Show fit	keratin 34
chr9_-_89178810 Show fit	0.06	ENST00000375835.9	SHC3 Ensembl NCBI GeneCards UniProt Show fit	SHC adaptor protein 3
chr4_-_167234579 Show fit	0.05	ENST00000502330.5 ENST00000357154.7 ENST00000421836.6	SPOCK3 Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr1_+_99264275 Show fit	0.05	ENST00000457765.6	PLPPR4 Ensembl NCBI GeneCards UniProt Show fit	phospholipid phosphatase related 4
chr16_-_74985070 Show fit	0.05	ENST00000616369.4 ENST00000262144.11	WDR59 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 59
chr1_-_203351115 Show fit	0.05	ENST00000354955.5	FMOD Ensembl NCBI GeneCards UniProt Show fit	fibromodulin
chr12_+_8989535 Show fit	0.05	ENST00000356986.8	KLRG1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor G1
chr14_-_24114913 Show fit	0.05	ENST00000561028.6 ENST00000558280.1	NRL Ensembl NCBI GeneCards UniProt Show fit	neural retina leucine zipper
chr12_+_8989612 Show fit	0.05	ENST00000266551.8	KLRG1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor G1
chr1_+_247507058 Show fit	0.05	ENST00000527084.5 ENST00000536561.5 ENST00000527541.5 ENST00000366491.6 ENST00000366489.5 ENST00000526896.5	GCSAML Ensembl NCBI GeneCards UniProt Show fit	germinal center associated signaling and motility like
chrX_-_119565362 Show fit	0.05	ENST00000320339.8 ENST00000536133.2 ENST00000644802.2	STEEP1 Ensembl NCBI GeneCards UniProt Show fit	STING1 ER exit protein 1
chr2_-_182242031 Show fit	0.04	ENST00000358139.6	PDE1A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 1A
chr4_-_167234426 Show fit	0.04	ENST00000541354.5 ENST00000509854.5 ENST00000512681.5 ENST00000357545.9 ENST00000510741.5 ENST00000510403.5	SPOCK3 Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr1_-_173917281 Show fit	0.04	ENST00000367698.4	SERPINC1 Ensembl NCBI GeneCards UniProt Show fit	serpin family C member 1
chr8_-_30912998 Show fit	0.04	ENST00000643185.2	TEX15 Ensembl NCBI GeneCards UniProt Show fit	testis expressed 15, meiosis and synapsis associated
chr1_-_1574824 Show fit	0.04	ENST00000291386.4	SSU72 Ensembl NCBI GeneCards UniProt Show fit	SSU72 homolog, RNA polymerase II CTD phosphatase
chr1_-_51878799 Show fit	0.04	ENST00000354831.11 ENST00000544028.5	NRDC Ensembl NCBI GeneCards UniProt Show fit	nardilysin convertase
chr5_+_50665899 Show fit	0.04	ENST00000505697.6	PARP8 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 8
chr22_+_41976760 Show fit	0.04	ENST00000396426.7 ENST00000406029.5	SEPTIN3 Ensembl NCBI GeneCards UniProt Show fit	septin 3
chr17_+_7932101 Show fit	0.04	ENST00000576538.5 ENST00000380262.7 ENST00000563694.6 ENST00000570782.1	CNTROB Ensembl NCBI GeneCards UniProt Show fit	centrobin, centriole duplication and spindle assembly protein
chr17_-_61591192 Show fit	0.03	ENST00000521764.3	NACA2 Ensembl NCBI GeneCards UniProt Show fit	nascent polypeptide associated complex subunit alpha 2
chr2_+_170178136 Show fit	0.03	ENST00000409044.7 ENST00000408978.9	MYO3B Ensembl NCBI GeneCards UniProt Show fit	myosin IIIB
chr3_-_119660580 Show fit	0.03	ENST00000493094.6 ENST00000264231.7 ENST00000468801.1	POPDC2 Ensembl NCBI GeneCards UniProt Show fit	popeye domain containing 2
chr15_-_52568960 Show fit	0.03	ENST00000564163.5 ENST00000249822.9	ARPP19 Ensembl NCBI GeneCards UniProt Show fit	cAMP regulated phosphoprotein 19
chr3_-_54967088 Show fit	0.03	ENST00000493075.1	LRTM1 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeats and transmembrane domains 1
chrY_+_18546691 Show fit	0.03	ENST00000309834.8 ENST00000307393.3 ENST00000382856.2	HSFY1 Ensembl NCBI GeneCards UniProt Show fit	heat shock transcription factor Y-linked 1
chr2_-_182522703 Show fit	0.03	ENST00000410103.1	PDE1A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 1A
chrX_+_30247139 Show fit	0.03	ENST00000397548.4	MAGEB1 Ensembl NCBI GeneCards UniProt Show fit	MAGE family member B1
chr4_-_167234266 Show fit	0.03	ENST00000511269.5 ENST00000506697.5 ENST00000512042.1	SPOCK3 Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr2_-_182522556 Show fit	0.03	ENST00000435564.5	PDE1A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 1A
chr8_+_144104454 Show fit	0.02	ENST00000322428.10	MAF1 Ensembl NCBI GeneCards UniProt Show fit	MAF1 homolog, negative regulator of RNA polymerase III
chr18_+_26226472 Show fit	0.02	ENST00000578121.5	TAF4B Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 4b
chr2_+_120013111 Show fit	0.02	ENST00000331393.8 ENST00000443124.5	EPB41L5 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 5
chrX_+_37990773 Show fit	0.02	ENST00000341016.5	H2AP Ensembl NCBI GeneCards UniProt Show fit	H2A.P histone
chr8_+_144104512 Show fit	0.02	ENST00000534585.5	MAF1 Ensembl NCBI GeneCards UniProt Show fit	MAF1 homolog, negative regulator of RNA polymerase III
chr18_+_58362467 Show fit	0.02	ENST00000675101.1	NEDD4L Ensembl NCBI GeneCards UniProt Show fit	NEDD4 like E3 ubiquitin protein ligase
chr11_+_71999927 Show fit	0.02	ENST00000393707.4	IL18BP Ensembl NCBI GeneCards UniProt Show fit	interleukin 18 binding protein
chr1_+_154272589 Show fit	0.02	ENST00000457918.6 ENST00000483970.6 ENST00000328703.12 ENST00000435087.1 ENST00000532105.1	HAX1 Ensembl NCBI GeneCards UniProt Show fit	HCLS1 associated protein X-1
chr14_+_73612517 Show fit	0.02	ENST00000645972.2	ACOT6 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA thioesterase 6
chr2_+_74554692 Show fit	0.01	ENST00000233668.10 ENST00000340004.6	DOK1 Ensembl NCBI GeneCards UniProt Show fit	docking protein 1
chr2_-_157327699 Show fit	0.01	ENST00000397283.6	ERMN Ensembl NCBI GeneCards UniProt Show fit	ermin
chr11_+_65354745 Show fit	0.01	ENST00000309880.6	TIGD3 Ensembl NCBI GeneCards UniProt Show fit	tigger transposable element derived 3
chr1_-_155244645 Show fit	0.01	ENST00000327247.9	GBA Ensembl NCBI GeneCards UniProt Show fit	glucosylceramidase beta
chr10_-_1048879 Show fit	0.01	ENST00000429642.2	IDI1 Ensembl NCBI GeneCards UniProt Show fit	isopentenyl-diphosphate delta isomerase 1
chr9_-_35650902 Show fit	0.01	ENST00000259608.8 ENST00000618781.1	SIT1 Ensembl NCBI GeneCards UniProt Show fit	signaling threshold regulating transmembrane adaptor 1
chr11_-_19060706 Show fit	0.01	ENST00000329773.3	MRGPRX2 Ensembl NCBI GeneCards UniProt Show fit	MAS related GPR family member X2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.7	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.4	2.1	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.2	0.5	GO:0036333	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1	0.6	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.5	GO:0097338	response to clozapine(GO:0097338)
0.1	0.3	GO:0070901	mitochondrial tRNA methylation(GO:0070901)
0.1	2.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.1	0.5	GO:0015705	iodide transport(GO:0015705)
0.1	0.4	GO:0051673	membrane disruption in other organism(GO:0051673)
0.1	0.5	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.2	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.1	0.2	GO:0019836	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1	0.4	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.1	0.4	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.1	0.2	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1	0.4	GO:0070995	NADPH oxidation(GO:0070995)
0.1	0.4	GO:0036486	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1	0.4	GO:0060467	negative regulation of fertilization(GO:0060467)
0.0	0.3	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.5	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.2	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.3	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0	0.4	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.0	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0001827	inner cell mass cell fate commitment(GO:0001827) germ-line stem cell population maintenance(GO:0030718)
0.0	0.6	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	1.4	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.2	GO:0031133	regulation of axon diameter(GO:0031133)
0.0	0.1	GO:0002769	natural killer cell inhibitory signaling pathway(GO:0002769)
0.0	0.2	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.3	GO:0034127	regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127)
0.0	0.1	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.0	0.4	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.2	GO:0051414	response to cortisol(GO:0051414)
0.0	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.2	GO:0032532	regulation of microvillus length(GO:0032532)
0.0	0.1	GO:0042636	negative regulation of hair cycle(GO:0042636)
0.0	0.3	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.3	GO:1901748	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0	0.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.2	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.1	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.1	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.3	GO:0006853	carnitine shuttle(GO:0006853)
0.0	0.3	GO:1900115	extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	1.2	GO:0030574	collagen catabolic process(GO:0030574)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	0.3	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.1	0.4	GO:1990031	pinceau fiber(GO:1990031)
0.1	0.6	GO:0000796	condensin complex(GO:0000796)
0.1	0.2	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0	0.1	GO:0034515	proteasome storage granule(GO:0034515)
0.0	0.2	GO:0000801	central element(GO:0000801)
0.0	0.5	GO:0045120	pronucleus(GO:0045120)
0.0	0.5	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.4	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.2	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.2	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.3	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:0045180	basal cortex(GO:0045180)
0.0	1.1	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	1.4	GO:0035578	azurophil granule lumen(GO:0035578)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.1	GO:0043515	kinetochore binding(GO:0043515)
0.2	1.7	GO:1904288	BAT3 complex binding(GO:1904288)
0.2	0.5	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.5	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.1	0.4	GO:0002060	purine nucleobase binding(GO:0002060)
0.1	0.5	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.1	1.4	GO:0051400	BH domain binding(GO:0051400)
0.1	0.6	GO:0008131	primary amine oxidase activity(GO:0008131)
0.1	0.3	GO:0023024	MHC class I protein complex binding(GO:0023024)
0.1	0.3	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0	0.4	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.5	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.5	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.3	GO:0004679	AMP-activated protein kinase activity(GO:0004679) phosphorylase kinase regulator activity(GO:0008607)
0.0	0.4	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.3	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.2	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.5	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0004419	hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0	0.1	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.1	GO:0016426	tRNA (adenine) methyltransferase activity(GO:0016426)
0.0	0.3	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.0	0.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.3	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.4	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.7	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.0	GO:0000994	RNA polymerase III core binding(GO:0000994)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.4	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	3.3	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
2.6	PID PLK1 PATHWAY	PLK1 signaling events
0.3	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.6	PID AURORA B PATHWAY	Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
1.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.4	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.5	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts

Results for PAX3

Z-value: 0.53

Motif logo

Transcription factors associated with PAX3

Activity-expression correlation:

Activity profile of PAX3 motif

Sorted Z-values of PAX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX3

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: