Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for PBX2

Z-value: 0.25

Motif logo

logo of

Transcription factors associated with PBX2

Gene Symbol Gene ID Gene Info
PBX2
ENSG00000204304.12 PBX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX2hg38_v1_chr6_-_32190170_321902140.604.7e-04Click!

Activity profile of PBX2 motif

Sorted Z-values of PBX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_31217511 0.92 ENST00000403897.4
CAPN14
calpain 14
chr14_-_55191534 0.66 ENST00000395425.6
ENST00000247191.7
DLGAP5
DLG associated protein 5
chr12_-_27971970 0.60 ENST00000395872.5
ENST00000201015.8
PTHLH
parathyroid hormone like hormone
chr12_-_27972725 0.48 ENST00000545234.6
PTHLH
parathyroid hormone like hormone
chr3_+_190615308 0.45 ENST00000412080.1
IL1RAP
interleukin 1 receptor accessory protein
chr15_+_67125707 0.35 ENST00000540846.6
SMAD3
SMAD family member 3
chr2_+_233692881 0.27 ENST00000305139.11
UGT1A6
UDP glucuronosyltransferase family 1 member A6
chr14_-_23155302 0.24 ENST00000529705.6
SLC7A8
solute carrier family 7 member 8
chr3_+_189171948 0.22 ENST00000345063.8
TPRG1
tumor protein p63 regulated 1
chr11_+_62665305 0.18 ENST00000532971.2
CSKMT
citrate synthase lysine methyltransferase
chr11_-_55936400 0.16 ENST00000301532.3
OR5I1
olfactory receptor family 5 subfamily I member 1
chrX_+_46837034 0.16 ENST00000218340.4
RP2
RP2 activator of ARL3 GTPase
chr22_-_30246739 0.15 ENST00000403987.3
ENST00000249075.4
LIF
LIF interleukin 6 family cytokine
chr4_+_37960397 0.15 ENST00000504686.2
PTTG2
pituitary tumor-transforming 2
chr2_-_99301195 0.14 ENST00000308528.9
LYG1
lysozyme g1
chr7_+_134843884 0.14 ENST00000445569.6
CALD1
caldesmon 1
chr1_+_206865620 0.14 ENST00000367098.6
IL20
interleukin 20
chr10_-_44978789 0.14 ENST00000448778.1
ENST00000298295.4
DEPP1
DEPP1 autophagy regulator
chr2_+_112275588 0.14 ENST00000409871.6
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr1_+_61952283 0.14 ENST00000307297.8
PATJ
PATJ crumbs cell polarity complex component
chr12_+_4590075 0.14 ENST00000540757.6
DYRK4
dual specificity tyrosine phosphorylation regulated kinase 4
chr9_+_107306459 0.13 ENST00000457811.1
RAD23B
RAD23 homolog B, nucleotide excision repair protein
chr11_-_111923722 0.13 ENST00000527950.5
CRYAB
crystallin alpha B
chrX_+_120604199 0.12 ENST00000371315.3
MCTS1
MCTS1 re-initiation and release factor
chr14_+_64388296 0.11 ENST00000554739.5
ENST00000554768.6
ENST00000652179.1
ENST00000652337.1
ENST00000557370.3
MTHFD1
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
chr11_-_104898670 0.11 ENST00000422698.6
CASP12
caspase 12 (gene/pseudogene)
chr17_-_30824665 0.11 ENST00000324238.7
CRLF3
cytokine receptor like factor 3
chr2_+_203867943 0.10 ENST00000295854.10
ENST00000487393.1
ENST00000472206.1
CTLA4
cytotoxic T-lymphocyte associated protein 4
chr10_+_122560751 0.09 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
DMBT1
deleted in malignant brain tumors 1
chr17_-_1229706 0.09 ENST00000574139.7
ABR
ABR activator of RhoGEF and GTPase
chr1_+_101237009 0.08 ENST00000305352.7
S1PR1
sphingosine-1-phosphate receptor 1
chr10_+_122560679 0.08 ENST00000657942.1
DMBT1
deleted in malignant brain tumors 1
chr2_+_203867764 0.08 ENST00000648405.2
CTLA4
cytotoxic T-lymphocyte associated protein 4
chr2_+_233693659 0.07 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase family 1 member A6
chr10_+_122560639 0.07 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
DMBT1
deleted in malignant brain tumors 1
chr2_+_20447065 0.07 ENST00000272233.6
RHOB
ras homolog family member B
chr3_-_52830664 0.07 ENST00000266041.9
ENST00000406595.5
ENST00000485816.5
ITIH4
inter-alpha-trypsin inhibitor heavy chain 4
chr2_+_33436304 0.07 ENST00000402538.7
RASGRP3
RAS guanyl releasing protein 3
chr10_-_73808616 0.06 ENST00000299641.8
NDST2
N-deacetylase and N-sulfotransferase 2
chr3_-_129440007 0.06 ENST00000503197.5
ENST00000249910.5
ENST00000507208.1
ENST00000393278.6
MBD4
methyl-CpG binding domain 4, DNA glycosylase
chr5_+_55024250 0.06 ENST00000231009.3
GZMK
granzyme K
chrX_+_120604084 0.06 ENST00000371317.10
MCTS1
MCTS1 re-initiation and release factor
chr18_-_75208417 0.06 ENST00000581620.1
ENST00000582437.1
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr7_-_151520080 0.06 ENST00000496004.5
RHEB
Ras homolog, mTORC1 binding
chr2_-_264024 0.06 ENST00000403712.6
ENST00000356150.10
ENST00000626873.2
ENST00000405430.5
SH3YL1
SH3 and SYLF domain containing 1
chr3_+_160225409 0.05 ENST00000326474.5
C3orf80
chromosome 3 open reading frame 80
chr1_+_61952036 0.05 ENST00000646453.1
ENST00000635137.1
PATJ
PATJ crumbs cell polarity complex component
chr7_-_112939773 0.04 ENST00000297145.9
BMT2
base methyltransferase of 25S rRNA 2 homolog
chr3_-_129439925 0.04 ENST00000429544.7
MBD4
methyl-CpG binding domain 4, DNA glycosylase
chr1_-_114780624 0.04 ENST00000060969.6
ENST00000369528.9
SIKE1
suppressor of IKBKE 1
chr9_+_122510802 0.04 ENST00000335302.5
OR1J2
olfactory receptor family 1 subfamily J member 2
chr2_+_44168866 0.03 ENST00000282412.9
ENST00000409432.7
ENST00000378551.6
ENST00000345249.8
PPM1B
protein phosphatase, Mg2+/Mn2+ dependent 1B
chrX_-_31178220 0.03 ENST00000681026.1
DMD
dystrophin
chr18_-_75209126 0.03 ENST00000322342.4
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr7_-_33100886 0.02 ENST00000448915.1
RP9
RP9 pre-mRNA splicing factor
chr4_+_99574812 0.02 ENST00000422897.6
ENST00000265517.10
MTTP
microsomal triglyceride transfer protein
chrX_-_31178149 0.02 ENST00000679437.1
DMD
dystrophin
chr14_+_22516273 0.00 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr5_+_141392616 0.00 ENST00000398604.3
PCDHGA8
protocadherin gamma subfamily A, 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 1.1 GO:0002076 osteoblast development(GO:0002076)
0.0 0.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0035375 zymogen binding(GO:0035375)
0.1 0.5 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0004487 formate-tetrahydrofolate ligase activity(GO:0004329) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 1.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation