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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PGR

Z-value: 0.61

Motif logo

Transcription factors associated with PGR

Gene Symbol Gene ID Gene Info
ENSG00000082175.15 PGR

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PGRhg38_v1_chr11_-_101129706_101129735,
hg38_v1_chr11_-_101129042_101129070
-0.212.6e-01Click!

Activity profile of PGR motif

Sorted Z-values of PGR motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PGR

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_71157992 0.98 ENST00000247829.8
tetraspanin 8
chr12_-_71157872 0.97 ENST00000546561.2
tetraspanin 8
chr11_+_6876625 0.86 ENST00000379829.2
olfactory receptor family 10 subfamily A member 4
chr5_-_122078249 0.65 ENST00000231004.5
lysyl oxidase
chr1_-_156859087 0.58 ENST00000368195.4
insulin receptor related receptor
chr11_+_27041313 0.57 ENST00000528583.5
gamma-butyrobetaine hydroxylase 1
chr7_+_74028127 0.56 ENST00000438880.5
ENST00000414324.5
ENST00000380562.8
ENST00000380575.8
ENST00000380584.8
ENST00000458204.5
ENST00000357036.9
ENST00000417091.5
ENST00000429192.5
ENST00000252034.12
ENST00000442310.5
ENST00000380553.8
ENST00000380576.9
ENST00000428787.5
ENST00000320399.10
elastin
chr20_+_23440248 0.53 ENST00000246020.2
cystatin like 1
chr4_+_185396834 0.53 ENST00000335174.6
ankyrin repeat domain 37
chr10_+_47322450 0.50 ENST00000581492.3
growth differentiation factor 2
chr1_+_25616780 0.50 ENST00000374332.9
mannosidase alpha class 1C member 1
chr10_-_77140757 0.50 ENST00000637862.2
potassium calcium-activated channel subfamily M alpha 1
chr13_+_23570370 0.48 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr5_+_68288346 0.48 ENST00000320694.12
phosphoinositide-3-kinase regulatory subunit 1
chr7_+_105963253 0.45 ENST00000478080.5
ENST00000317716.14
cadherin related family member 3
chr20_+_23439685 0.45 ENST00000619238.1
ENST00000347397.5
cystatin like 1
chr5_-_147453888 0.42 ENST00000398514.7
dihydropyrimidinase like 3
chr17_+_76001715 0.42 ENST00000586261.2
cyclin dependent kinase 3
chr5_+_140882116 0.42 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
protocadherin alpha 13
chr11_+_111298840 0.42 ENST00000528846.5
ENST00000614153.4
colorectal cancer associated 2
chr7_+_74027770 0.40 ENST00000445912.5
ENST00000621115.4
elastin
chr17_+_7857695 0.39 ENST00000571846.5
cytochrome b5 domain containing 1
chr2_-_208129824 0.39 ENST00000282141.4
crystallin gamma C
chr6_-_46954922 0.38 ENST00000265417.7
adhesion G protein-coupled receptor F5
chr20_+_59628609 0.38 ENST00000541461.5
phosphatase and actin regulator 3
chr7_-_78489900 0.38 ENST00000636039.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr12_+_130953898 0.37 ENST00000261654.10
adhesion G protein-coupled receptor D1
chr9_+_124853417 0.36 ENST00000613760.4
ENST00000618744.4
ENST00000373574.2
WD repeat domain 38
chr4_+_85604146 0.34 ENST00000512201.5
Rho GTPase activating protein 24
chr5_+_102865805 0.34 ENST00000346918.7
peptidylglycine alpha-amidating monooxygenase
chr7_+_74028066 0.34 ENST00000431562.5
ENST00000320492.11
ENST00000438906.5
elastin
chr5_+_175871670 0.34 ENST00000514150.5
complexin 2
chr3_-_58577648 0.33 ENST00000394481.5
family with sequence similarity 107 member A
chr16_+_78022538 0.33 ENST00000651443.1
ENST00000299642.10
C-type lectin domain family 3 member A
chrX_+_16946862 0.33 ENST00000303843.7
RALBP1 associated Eps domain containing 2
chr3_-_58577367 0.32 ENST00000464064.5
ENST00000360997.7
family with sequence similarity 107 member A
chr9_+_113463697 0.32 ENST00000317613.10
regulator of G protein signaling 3
chr19_-_39934626 0.32 ENST00000616721.6
Fc fragment of IgG binding protein
chr20_-_61998132 0.32 ENST00000474089.5
TATA-box binding protein associated factor 4
chr1_+_148748774 0.32 ENST00000322209.5
nudix hydrolase 4B
chr3_+_52420955 0.32 ENST00000465863.1
PHD finger protein 7
chr11_-_112074239 0.32 ENST00000530641.5
PIH1 domain containing 2
chr12_+_7061206 0.31 ENST00000423384.5
ENST00000413211.5
complement C1s
chr5_-_16616972 0.30 ENST00000682564.1
ENST00000306320.10
ENST00000682229.1
reticulophagy regulator 1
chr17_-_44199206 0.29 ENST00000589805.1
ataxin 7 like 3
chr3_+_41194741 0.28 ENST00000643541.1
ENST00000426215.5
ENST00000645210.1
ENST00000646381.1
ENST00000405570.6
ENST00000642248.1
ENST00000433400.6
catenin beta 1
chr20_-_3781440 0.28 ENST00000379756.3
sperm flagellar 1
chr8_+_40153475 0.28 ENST00000315792.5
transcriptional and immune response regulator
chr1_+_12464912 0.27 ENST00000543766.2
vacuolar protein sorting 13 homolog D
chr19_+_13024917 0.27 ENST00000587260.1
nuclear factor I X
chr19_+_13024573 0.27 ENST00000358552.7
ENST00000360105.8
ENST00000588228.5
ENST00000676441.1
ENST00000591028.1
nuclear factor I X
chr1_+_152719522 0.26 ENST00000368775.3
chromosome 1 open reading frame 68
chr10_+_102419189 0.26 ENST00000432590.5
F-box and leucine rich repeat protein 15
chr1_-_85404494 0.26 ENST00000633113.1
dimethylarginine dimethylaminohydrolase 1
chr2_-_174847015 0.25 ENST00000650938.1
chimerin 1
chr2_-_174846405 0.25 ENST00000409597.5
ENST00000413882.6
chimerin 1
chr7_-_93226449 0.25 ENST00000394468.7
ENST00000453812.2
HEPACAM family member 2
chr17_-_35943662 0.24 ENST00000618542.4
lysozyme like 6
chr12_-_49187369 0.24 ENST00000547939.6
tubulin alpha 1a
chr17_-_35943707 0.24 ENST00000615905.5
lysozyme like 6
chr8_-_107497909 0.24 ENST00000517746.6
angiopoietin 1
chr5_+_157180816 0.23 ENST00000422843.8
IL2 inducible T cell kinase
chr14_+_24205684 0.23 ENST00000339917.10
testis specific serine kinase 4
chr3_-_114624979 0.22 ENST00000676079.1
zinc finger and BTB domain containing 20
chr4_+_127880876 0.22 ENST00000270861.10
ENST00000515069.5
ENST00000513090.5
ENST00000507249.5
polo like kinase 4
chr14_+_24205725 0.22 ENST00000556621.5
ENST00000287913.10
ENST00000428351.2
ENST00000555092.1
testis specific serine kinase 4
chr14_+_52314280 0.21 ENST00000557436.1
ENST00000245457.6
prostaglandin E receptor 2
chr2_-_157325808 0.21 ENST00000410096.6
ENST00000420719.6
ENST00000409216.5
ENST00000419116.2
ermin
chr2_+_69013379 0.21 ENST00000409349.7
ANTXR cell adhesion molecule 1
chr8_-_42768602 0.21 ENST00000534622.5
cholinergic receptor nicotinic alpha 6 subunit
chr10_+_122271292 0.21 ENST00000260723.6
BTB domain containing 16
chr3_+_25428233 0.21 ENST00000437042.6
ENST00000330688.9
retinoic acid receptor beta
chr14_+_78170336 0.21 ENST00000634499.2
ENST00000335750.7
neurexin 3
chr7_-_130441136 0.21 ENST00000675596.1
ENST00000676312.1
centrosomal protein 41
chr8_-_42768781 0.21 ENST00000276410.7
cholinergic receptor nicotinic alpha 6 subunit
chr5_-_124745315 0.21 ENST00000306315.9
zinc finger protein 608
chr10_-_121596117 0.20 ENST00000351936.11
fibroblast growth factor receptor 2
chr17_+_7484357 0.20 ENST00000674977.2
RNA polymerase II subunit A
chr4_-_48134200 0.20 ENST00000264316.9
TXK tyrosine kinase
chr2_-_89117844 0.20 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr6_+_31655888 0.20 ENST00000375916.4
apolipoprotein M
chr9_-_124500986 0.20 ENST00000373587.3
nuclear receptor subfamily 5 group A member 1
chr12_+_57455266 0.20 ENST00000266646.3
inhibin subunit beta E
chr11_-_62591500 0.19 ENST00000476907.6
ENST00000278279.7
terminal uridylyl transferase 1, U6 snRNA-specific
chr3_-_114624921 0.19 ENST00000393785.6
zinc finger and BTB domain containing 20
chr5_+_141417659 0.18 ENST00000398594.4
protocadherin gamma subfamily B, 7
chr10_-_28282086 0.18 ENST00000375719.7
ENST00000375732.5
membrane palmitoylated protein 7
chr19_-_51026593 0.18 ENST00000600362.5
ENST00000453757.8
ENST00000601671.1
kallikrein related peptidase 11
chr1_-_36482904 0.18 ENST00000373106.6
colony stimulating factor 3 receptor
chr17_-_7207245 0.18 ENST00000649971.1
discs large MAGUK scaffold protein 4
chr12_+_55549602 0.18 ENST00000641569.1
ENST00000641851.1
olfactory receptor family 6 subfamily C member 4
chrX_+_54807599 0.18 ENST00000375053.6
ENST00000627068.2
ENST00000375068.6
ENST00000347546.8
MAGE family member D2
chr9_-_34665985 0.18 ENST00000416454.5
ENST00000544078.2
ENST00000421828.7
ENST00000423809.5
novel protein
chr12_+_56079843 0.17 ENST00000549282.5
ENST00000549061.5
ENST00000683059.1
erb-b2 receptor tyrosine kinase 3
chr5_-_59430600 0.17 ENST00000636120.1
phosphodiesterase 4D
chr9_+_122519141 0.17 ENST00000340750.1
olfactory receptor family 1 subfamily J member 4
chr1_-_26067622 0.17 ENST00000374272.4
tripartite motif containing 63
chr11_+_6481473 0.17 ENST00000530751.1
ENST00000254616.11
translocase of inner mitochondrial membrane 10B
chr5_-_16617085 0.17 ENST00000684521.1
reticulophagy regulator 1
chr6_-_89217339 0.17 ENST00000454853.7
gamma-aminobutyric acid type A receptor subunit rho1
chr19_-_55179390 0.16 ENST00000590851.5
synaptotagmin 5
chr12_-_6375556 0.16 ENST00000228916.7
sodium channel epithelial 1 subunit alpha
chr17_-_28576882 0.16 ENST00000395319.7
ENST00000581807.5
ENST00000226253.9
ENST00000584086.5
ENST00000395321.6
aldolase, fructose-bisphosphate C
chr2_+_27282419 0.16 ENST00000380075.7
ENST00000296098.4
tripartite motif containing 54
chr11_+_118883884 0.16 ENST00000292174.5
C-X-C motif chemokine receptor 5
chr6_-_75493773 0.16 ENST00000237172.12
filamin A interacting protein 1
chr5_+_138084015 0.16 ENST00000504809.5
ENST00000506684.6
ENST00000398754.1
Wnt family member 8A
chr11_+_123525822 0.16 ENST00000322282.11
ENST00000529750.5
GRAM domain containing 1B
chr6_-_159045010 0.16 ENST00000338313.5
T cell activation RhoGTPase activating protein
chr3_+_29281552 0.16 ENST00000452462.5
ENST00000456853.1
RNA binding motif single stranded interacting protein 3
chr2_-_31580929 0.15 ENST00000622030.2
steroid 5 alpha-reductase 2
chr10_-_13972355 0.15 ENST00000264546.10
FERM domain containing 4A
chr1_+_1915080 0.15 ENST00000378604.3
calmodulin like 6
chr11_-_66958366 0.15 ENST00000651036.1
ENST00000652125.1
ENST00000531614.6
ENST00000524491.6
ENST00000529047.6
ENST00000393960.7
ENST00000393958.7
ENST00000528403.6
ENST00000651854.1
pyruvate carboxylase
chr19_+_51127030 0.15 ENST00000599948.1
sialic acid binding Ig like lectin 9
chr3_-_114624193 0.15 ENST00000481632.5
zinc finger and BTB domain containing 20
chrX_+_71223216 0.15 ENST00000361726.7
gap junction protein beta 1
chr4_-_65669935 0.15 ENST00000354839.8
ENST00000432638.6
EPH receptor A5
chr6_-_43308797 0.15 ENST00000274990.4
ENST00000372569.8
cysteine rich protein 3
chr6_+_156776020 0.14 ENST00000346085.10
AT-rich interaction domain 1B
chr5_-_38557459 0.14 ENST00000511561.1
LIF receptor subunit alpha
chr11_-_625168 0.14 ENST00000349570.11
cadherin related family member 5
chr8_+_10672646 0.14 ENST00000521818.1
chromosome 8 open reading frame 74
chr9_+_2159672 0.14 ENST00000634343.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_27014746 0.14 ENST00000648289.1
ENST00000458529.5
ENST00000402218.1
microtubule associated protein RP/EB family member 3
chr11_-_75668566 0.14 ENST00000526740.3
microtubule associated protein 6
chr18_+_58196736 0.14 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr15_+_73683938 0.14 ENST00000567189.5
CD276 molecule
chr7_+_22727147 0.13 ENST00000426291.5
ENST00000401651.5
ENST00000258743.10
ENST00000407492.5
ENST00000401630.7
ENST00000406575.1
interleukin 6
chr2_-_164842011 0.13 ENST00000409184.8
ENST00000456693.5
cordon-bleu WH2 repeat protein like 1
chr10_-_95441015 0.13 ENST00000371241.5
ENST00000354106.7
ENST00000371239.5
ENST00000361941.7
ENST00000277982.9
ENST00000371245.7
sorbin and SH3 domain containing 1
chr18_-_55351977 0.13 ENST00000643689.1
transcription factor 4
chr1_-_247458105 0.13 ENST00000641149.1
ENST00000641527.1
olfactory receptor family 2 subfamily B member 11
chr9_+_2159850 0.13 ENST00000416751.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_-_87529460 0.13 ENST00000418378.5
SPARC like 1
chr1_+_26787667 0.12 ENST00000674335.1
phosphatidylinositol glycan anchor biosynthesis class V
chr12_-_7091873 0.12 ENST00000538050.5
ENST00000536053.6
complement C1r
chr4_-_87529359 0.12 ENST00000458304.2
ENST00000282470.11
SPARC like 1
chr19_+_15793951 0.12 ENST00000308940.8
olfactory receptor family 10 subfamily H member 5
chr2_-_164841812 0.12 ENST00000652658.2
ENST00000444537.5
ENST00000414843.5
cordon-bleu WH2 repeat protein like 1
chr17_+_41249687 0.12 ENST00000334109.3
keratin associated protein 9-4
chr12_+_49752964 0.12 ENST00000547798.1
transmembrane BAX inhibitor motif containing 6
chr15_+_31366138 0.12 ENST00000558844.1
Kruppel like factor 13
chr9_+_1050330 0.12 ENST00000382255.7
ENST00000382251.7
ENST00000412350.6
ENST00000358146.7
doublesex and mab-3 related transcription factor 2
chr18_-_55586092 0.12 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
transcription factor 4
chr6_+_116399395 0.12 ENST00000644499.1
novel protein
chr12_+_57610150 0.12 ENST00000333972.11
Rho guanine nucleotide exchange factor 25
chr15_+_48191648 0.12 ENST00000646012.1
ENST00000561127.5
ENST00000647546.1
ENST00000559641.5
ENST00000417307.3
solute carrier family 12 member 1
cortexin 2
chr1_-_110391041 0.12 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
solute carrier family 16 member 4
chr15_-_25865076 0.12 ENST00000619904.1
ATPase phospholipid transporting 10A (putative)
chr8_+_26514021 0.12 ENST00000521913.7
dihydropyrimidinase like 2
chr20_+_157447 0.11 ENST00000382388.4
defensin beta 127
chrX_-_101386166 0.11 ENST00000308731.8
ENST00000372880.5
Bruton tyrosine kinase
chr22_-_36239517 0.11 ENST00000358502.10
ENST00000451256.6
apolipoprotein L2
chr12_-_88580459 0.11 ENST00000552044.1
ENST00000644744.1
ENST00000357116.4
KIT ligand
chr1_+_78004930 0.11 ENST00000370763.6
DnaJ heat shock protein family (Hsp40) member B4
chr6_-_41163182 0.11 ENST00000338469.3
triggering receptor expressed on myeloid cells 2
chr12_+_56267674 0.11 ENST00000546544.5
ENST00000553234.1
coenzyme Q10A
chr10_+_68106109 0.11 ENST00000540630.5
ENST00000354393.6
myopalladin
chr1_+_155051280 0.11 ENST00000449910.6
ENST00000359280.8
ENST00000360674.8
ENST00000368412.7
ENST00000355956.6
ENST00000271836.10
ENST00000368413.5
ENST00000356955.7
ENST00000531455.5
ENST00000447332.3
ADAM metallopeptidase domain 15
chr2_-_27308445 0.11 ENST00000296099.2
urocortin
chr1_-_179143044 0.11 ENST00000504405.5
ENST00000512653.5
ENST00000344730.7
ABL proto-oncogene 2, non-receptor tyrosine kinase
chr13_-_99016034 0.11 ENST00000448493.7
dedicator of cytokinesis 9
chr16_-_3256587 0.10 ENST00000536379.5
ENST00000541159.5
ENST00000339854.8
ENST00000219596.6
MEFV innate immuity regulator, pyrin
chr15_+_65550819 0.10 ENST00000569894.5
3-hydroxyacyl-CoA dehydratase 3
chr11_-_102452758 0.10 ENST00000398136.7
ENST00000361236.7
transmembrane protein 123
chr17_+_75754618 0.10 ENST00000584939.1
integrin subunit beta 4
chr19_+_15787661 0.10 ENST00000642092.2
olfactory receptor family 10 subfamily H member 5
chr19_+_42313374 0.10 ENST00000598766.1
ENST00000673187.1
transmembrane protein 145
chr1_-_114749900 0.10 ENST00000438362.6
cold shock domain containing E1
chr19_-_6720641 0.10 ENST00000245907.11
complement C3
chr10_-_59906509 0.10 ENST00000263102.7
coiled-coil domain containing 6
chr22_+_31248402 0.10 ENST00000333611.8
ENST00000340552.4
LIM domain kinase 2
chr14_-_106235582 0.10 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr12_-_88029385 0.10 ENST00000298699.7
ENST00000550553.5
chromosome 12 open reading frame 50
chr19_-_10335773 0.10 ENST00000592439.1
intercellular adhesion molecule 3
chr2_+_36696686 0.10 ENST00000379242.7
ENST00000389975.7
vitrin
chr15_+_42359454 0.10 ENST00000349748.8
ENST00000318023.11
ENST00000397163.8
calpain 3
chr7_+_143959927 0.10 ENST00000624504.1
olfactory receptor family 2 subfamily F member 1
chr7_+_23598144 0.09 ENST00000410069.1
coiled-coil domain containing 126
chr2_-_164841410 0.09 ENST00000342193.8
ENST00000375458.6
cordon-bleu WH2 repeat protein like 1
chr11_-_8810635 0.09 ENST00000527510.5
ENST00000528527.5
ENST00000313726.11
ENST00000528523.5
DENN domain containing 2B
chr19_+_42313298 0.09 ENST00000301204.8
ENST00000673205.1
transmembrane protein 145
chr15_-_43584864 0.09 ENST00000381885.5
ENST00000396923.7
diphosphoinositol pentakisphosphate kinase 1
chr2_+_225399684 0.09 ENST00000636099.1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr5_+_139293660 0.09 ENST00000512876.5
ENST00000513678.5
matrin 3
chr6_+_39792298 0.09 ENST00000633794.1
ENST00000274867.9
dishevelled associated activator of morphogenesis 2
chr8_+_22987400 0.09 ENST00000519685.5
Rho related BTB domain containing 2
chr8_+_22589240 0.09 ENST00000450780.6
ENST00000430850.6
ENST00000447849.2
ENST00000614502.4
ENST00000443561.3
novel protein
PDZ and LIM domain 2
chr11_+_55635113 0.09 ENST00000641760.1
olfactory receptor family 4 subfamily P member 4
chr19_-_42442938 0.09 ENST00000601181.6
C-X-C motif chemokine ligand 17
chr17_-_7484205 0.09 ENST00000311403.4
zinc finger and BTB domain containing 4
chr5_+_140125935 0.09 ENST00000333305.5
IgA inducing protein
chr4_+_183683849 0.09 ENST00000512476.1
trafficking protein particle complex 11
chrX_-_32155462 0.09 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chr2_+_37950432 0.08 ENST00000407257.5
ENST00000417700.6
ENST00000234195.7
ENST00000442857.5
regulator of microtubule dynamics 2
chr20_-_25339731 0.08 ENST00000450393.5
ENST00000491682.5
abhydrolase domain containing 12, lysophospholipase
chr3_-_125120813 0.08 ENST00000430155.6
solute carrier family 12 member 8
chr2_-_89010515 0.08 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr17_+_77451244 0.08 ENST00000591088.5
septin 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.1 0.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.3 GO:0018032 protein amidation(GO:0018032)
0.1 0.2 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.1 0.2 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.1 0.1 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.5 GO:0061709 reticulophagy(GO:0061709)
0.1 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:0014034 neural crest cell fate commitment(GO:0014034) canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
0.1 0.2 GO:0018963 phthalate metabolic process(GO:0018963)
0.1 0.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.2 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.2 GO:0007538 primary sex determination(GO:0007538)
0.1 0.1 GO:0002445 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.0 0.3 GO:1904501 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.5 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812) B cell selection(GO:0002339) B cell cytokine production(GO:0002368)
0.0 0.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0002585 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.0 0.4 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.2 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.0 0.2 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:1990637 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.0 0.4 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.4 GO:0071073 surfactant homeostasis(GO:0043129) positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 0.0 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.5 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.5 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.4 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 1.7 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.4 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.0 GO:0097490 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.0 GO:1901253 mesodermal cell fate determination(GO:0007500) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.0 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.0 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.1 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.0 GO:2001248 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.2 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.0 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0097186 amelogenesis(GO:0097186)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0071953 elastic fiber(GO:0071953)
0.1 0.5 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.3 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.0 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.6 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0051431 histone deacetylase regulator activity(GO:0035033) corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.0 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.0 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 2.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins