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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for PITX1
Z-value: 1.54
Motif logo
Transcription factors associated with PITX1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
PITX1
|
ENSG00000069011.16 | PITX1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PITX1 | hg38_v1_chr5_-_135034212_135034294 | 0.64 | 1.3e-04 | Click! |
Activity profile of PITX1 motif
Sorted Z-values of PITX1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of PITX1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 15.9 | GO:0002225 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803) |
| 2.1 | 8.4 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 1.6 | 4.7 | GO:0046108 | uridine metabolic process(GO:0046108) |
| 1.4 | 11.3 | GO:0060005 | vestibular reflex(GO:0060005) |
| 1.3 | 3.8 | GO:0001300 | chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 1.1 | 14.7 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 1.0 | 3.0 | GO:0006714 | sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) |
| 1.0 | 8.7 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.9 | 2.6 | GO:0046379 | extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) |
| 0.8 | 2.5 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 0.8 | 2.4 | GO:0038195 | urokinase plasminogen activator signaling pathway(GO:0038195) |
| 0.8 | 0.8 | GO:0002786 | regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) |
| 0.8 | 4.6 | GO:0035803 | egg coat formation(GO:0035803) |
| 0.7 | 6.3 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.7 | 3.4 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.6 | 5.2 | GO:0061370 | testosterone biosynthetic process(GO:0061370) |
| 0.6 | 3.8 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
| 0.6 | 1.9 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
| 0.6 | 2.5 | GO:0019072 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.6 | 2.9 | GO:1990426 | homologous recombination-dependent replication fork processing(GO:1990426) |
| 0.5 | 6.3 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.5 | 2.5 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) mitotic telomere maintenance via semi-conservative replication(GO:1902990) |
| 0.5 | 2.0 | GO:0070982 | L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982) |
| 0.5 | 3.9 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 0.4 | 2.6 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.4 | 1.3 | GO:0018013 | N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573) |
| 0.4 | 1.7 | GO:0044805 | late nucleophagy(GO:0044805) |
| 0.4 | 2.5 | GO:2001184 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184) |
| 0.4 | 2.5 | GO:0060631 | regulation of meiosis I(GO:0060631) |
| 0.4 | 1.6 | GO:0003290 | atrial septum secundum morphogenesis(GO:0003290) |
| 0.4 | 1.2 | GO:1904170 | regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172) |
| 0.4 | 3.2 | GO:0050689 | negative regulation of defense response to virus by host(GO:0050689) |
| 0.4 | 2.4 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.4 | 2.0 | GO:0071727 | toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727) |
| 0.4 | 4.7 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.4 | 2.2 | GO:1903797 | positive regulation of inorganic anion transmembrane transport(GO:1903797) |
| 0.4 | 1.4 | GO:0050960 | detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594) |
| 0.4 | 1.8 | GO:0006710 | androgen catabolic process(GO:0006710) |
| 0.4 | 1.1 | GO:0002339 | B cell selection(GO:0002339) |
| 0.3 | 1.7 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 0.3 | 1.3 | GO:0000711 | meiotic DNA repair synthesis(GO:0000711) |
| 0.3 | 1.0 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 0.3 | 3.0 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.3 | 1.3 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 0.3 | 1.3 | GO:1905167 | positive regulation of lysosomal protein catabolic process(GO:1905167) |
| 0.3 | 5.5 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.3 | 1.6 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) |
| 0.3 | 3.2 | GO:0014718 | positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) |
| 0.3 | 2.5 | GO:0072502 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.3 | 0.9 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
| 0.3 | 1.2 | GO:0046203 | spermidine catabolic process(GO:0046203) |
| 0.3 | 0.9 | GO:0018874 | benzoate metabolic process(GO:0018874) |
| 0.3 | 1.7 | GO:0050668 | cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668) |
| 0.3 | 1.1 | GO:0015855 | pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823) |
| 0.3 | 1.4 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.3 | 1.9 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.2 | 2.7 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.2 | 1.0 | GO:0060671 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 0.2 | 2.1 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.2 | 2.5 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
| 0.2 | 0.7 | GO:0035281 | pre-miRNA export from nucleus(GO:0035281) |
| 0.2 | 0.9 | GO:1900138 | negative regulation of phospholipase A2 activity(GO:1900138) |
| 0.2 | 4.1 | GO:1901748 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.2 | 1.8 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
| 0.2 | 1.6 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.2 | 1.1 | GO:1905165 | regulation of lysosomal protein catabolic process(GO:1905165) |
| 0.2 | 1.3 | GO:0086098 | angiotensin-activated signaling pathway involved in heart process(GO:0086098) |
| 0.2 | 0.9 | GO:0036135 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
| 0.2 | 1.3 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.2 | 0.7 | GO:0051039 | histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039) |
| 0.2 | 0.6 | GO:0050993 | dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993) |
| 0.2 | 0.6 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 0.2 | 0.9 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 0.2 | 1.7 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.2 | 0.6 | GO:0021503 | neural fold bending(GO:0021503) |
| 0.2 | 0.8 | GO:0032661 | regulation of interleukin-18 production(GO:0032661) |
| 0.2 | 0.8 | GO:1902463 | protein localization to cell leading edge(GO:1902463) |
| 0.2 | 1.8 | GO:0002741 | positive regulation of cytokine secretion involved in immune response(GO:0002741) |
| 0.2 | 2.3 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.2 | 1.0 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
| 0.2 | 0.8 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
| 0.2 | 1.3 | GO:0006565 | L-serine catabolic process(GO:0006565) |
| 0.2 | 0.9 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
| 0.2 | 0.9 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 0.2 | 0.7 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 0.2 | 1.7 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
| 0.2 | 0.7 | GO:0019249 | lactate biosynthetic process(GO:0019249) |
| 0.2 | 2.0 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.2 | 0.4 | GO:0038158 | granulocyte colony-stimulating factor signaling pathway(GO:0038158) |
| 0.2 | 0.7 | GO:0060467 | negative regulation of fertilization(GO:0060467) |
| 0.2 | 1.4 | GO:0045905 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.2 | 1.4 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
| 0.2 | 0.9 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 0.2 | 0.9 | GO:0009726 | detection of endogenous stimulus(GO:0009726) |
| 0.2 | 1.2 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.2 | 4.1 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.2 | 0.5 | GO:0061182 | negative regulation of chondrocyte development(GO:0061182) |
| 0.2 | 4.0 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.2 | 0.7 | GO:0090290 | positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158) |
| 0.2 | 0.7 | GO:1903423 | positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423) |
| 0.2 | 1.0 | GO:0045914 | negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 0.2 | 1.4 | GO:1903207 | neuron death in response to hydrogen peroxide(GO:0036476) positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208) |
| 0.2 | 1.5 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.2 | 0.6 | GO:0046035 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 0.2 | 3.4 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.2 | 1.9 | GO:0002934 | desmosome organization(GO:0002934) |
| 0.2 | 0.5 | GO:0014740 | negative regulation of muscle hyperplasia(GO:0014740) |
| 0.2 | 0.5 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 0.2 | 0.5 | GO:0046967 | cytosol to ER transport(GO:0046967) |
| 0.2 | 3.1 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
| 0.2 | 0.8 | GO:0045590 | negative regulation of regulatory T cell differentiation(GO:0045590) |
| 0.2 | 0.5 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
| 0.2 | 0.6 | GO:0019285 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 0.2 | 7.2 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.1 | 0.9 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.1 | 0.4 | GO:0001828 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
| 0.1 | 0.9 | GO:0098704 | fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 0.1 | 0.7 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.1 | 3.1 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
| 0.1 | 0.7 | GO:0045337 | geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) |
| 0.1 | 0.8 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.1 | 0.7 | GO:0070383 | DNA cytosine deamination(GO:0070383) |
| 0.1 | 1.1 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.1 | 1.1 | GO:0015811 | L-cystine transport(GO:0015811) |
| 0.1 | 1.0 | GO:0042539 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.1 | 1.1 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
| 0.1 | 1.2 | GO:0002863 | positive regulation of inflammatory response to antigenic stimulus(GO:0002863) |
| 0.1 | 0.4 | GO:0090187 | positive regulation of pancreatic juice secretion(GO:0090187) |
| 0.1 | 0.4 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 0.1 | 0.7 | GO:0042109 | lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109) |
| 0.1 | 1.3 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 1.2 | GO:0046886 | positive regulation of hormone biosynthetic process(GO:0046886) |
| 0.1 | 0.4 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 0.1 | 1.2 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.1 | 1.0 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
| 0.1 | 0.5 | GO:0071462 | cellular response to water deprivation(GO:0042631) cellular response to water stimulus(GO:0071462) |
| 0.1 | 0.4 | GO:1904719 | excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719) |
| 0.1 | 1.0 | GO:0002018 | renin-angiotensin regulation of aldosterone production(GO:0002018) |
| 0.1 | 0.6 | GO:0003070 | age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571) |
| 0.1 | 8.0 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.1 | 0.9 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
| 0.1 | 0.5 | GO:0050904 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904) |
| 0.1 | 2.5 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
| 0.1 | 1.0 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.1 | 0.4 | GO:0010915 | regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) |
| 0.1 | 0.6 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
| 0.1 | 1.5 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.1 | 0.5 | GO:2001247 | positive regulation of phosphatidylcholine biosynthetic process(GO:2001247) |
| 0.1 | 0.8 | GO:0046874 | quinolinate metabolic process(GO:0046874) |
| 0.1 | 0.3 | GO:0042357 | thiamine diphosphate metabolic process(GO:0042357) |
| 0.1 | 0.8 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.1 | 0.7 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.1 | 1.1 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.1 | 0.4 | GO:2000371 | regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373) |
| 0.1 | 1.0 | GO:0046689 | response to mercury ion(GO:0046689) |
| 0.1 | 0.5 | GO:1903862 | positive regulation of oxidative phosphorylation(GO:1903862) |
| 0.1 | 1.0 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
| 0.1 | 0.2 | GO:0001808 | negative regulation of type IV hypersensitivity(GO:0001808) |
| 0.1 | 0.5 | GO:0071034 | CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) |
| 0.1 | 0.7 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.1 | 1.1 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.1 | 0.1 | GO:0032627 | interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) |
| 0.1 | 0.3 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 0.1 | 0.6 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.1 | 2.9 | GO:0070498 | interleukin-1-mediated signaling pathway(GO:0070498) |
| 0.1 | 0.2 | GO:0045626 | negative regulation of T-helper 1 cell differentiation(GO:0045626) |
| 0.1 | 0.8 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.1 | 0.9 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.1 | 0.3 | GO:0046603 | negative regulation of mitotic centrosome separation(GO:0046603) |
| 0.1 | 0.7 | GO:0034128 | negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) |
| 0.1 | 1.2 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 0.5 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 0.1 | 0.3 | GO:0043321 | regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) |
| 0.1 | 1.0 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 0.1 | 0.2 | GO:0036292 | DNA rewinding(GO:0036292) |
| 0.1 | 0.6 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.1 | 0.7 | GO:0043382 | positive regulation of memory T cell differentiation(GO:0043382) |
| 0.1 | 1.0 | GO:1903944 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 0.1 | 0.4 | GO:2000813 | negative regulation of barbed-end actin filament capping(GO:2000813) |
| 0.1 | 0.9 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
| 0.1 | 0.4 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
| 0.1 | 1.1 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.1 | 1.0 | GO:2001171 | positive regulation of ATP biosynthetic process(GO:2001171) |
| 0.1 | 4.3 | GO:0097435 | fibril organization(GO:0097435) |
| 0.1 | 0.3 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 0.1 | 0.3 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 0.1 | 0.3 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
| 0.1 | 0.5 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180) |
| 0.1 | 0.3 | GO:0048808 | male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598) |
| 0.1 | 0.2 | GO:0071680 | response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) |
| 0.1 | 0.6 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
| 0.1 | 0.2 | GO:0038162 | erythropoietin-mediated signaling pathway(GO:0038162) |
| 0.1 | 1.6 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.1 | 2.3 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.1 | 0.7 | GO:0043129 | surfactant homeostasis(GO:0043129) |
| 0.1 | 0.5 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 0.1 | 1.9 | GO:0006346 | methylation-dependent chromatin silencing(GO:0006346) |
| 0.1 | 4.5 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.1 | 0.6 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.1 | 0.5 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 0.1 | 0.9 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
| 0.1 | 2.3 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.1 | 0.2 | GO:0051387 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) |
| 0.1 | 1.4 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.1 | 0.8 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.1 | 1.3 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.1 | 1.1 | GO:0051546 | keratinocyte migration(GO:0051546) |
| 0.1 | 1.1 | GO:0019317 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.1 | 0.1 | GO:2000619 | negative regulation of histone H4-K16 acetylation(GO:2000619) |
| 0.1 | 0.4 | GO:0039526 | suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526) |
| 0.1 | 1.4 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.1 | 0.4 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.1 | 0.6 | GO:0032218 | riboflavin transport(GO:0032218) |
| 0.1 | 0.2 | GO:0019836 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
| 0.1 | 0.2 | GO:1903259 | exon-exon junction complex disassembly(GO:1903259) |
| 0.1 | 0.2 | GO:0090324 | negative regulation of oxidative phosphorylation(GO:0090324) |
| 0.1 | 0.7 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
| 0.1 | 3.2 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) |
| 0.1 | 0.1 | GO:0005988 | lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) |
| 0.1 | 0.8 | GO:0045651 | positive regulation of macrophage differentiation(GO:0045651) |
| 0.1 | 0.3 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
| 0.1 | 1.3 | GO:0043383 | negative T cell selection(GO:0043383) |
| 0.1 | 0.5 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 0.1 | 0.9 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.1 | 0.6 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.1 | 0.3 | GO:0010566 | regulation of ketone biosynthetic process(GO:0010566) |
| 0.1 | 0.2 | GO:0006212 | uracil catabolic process(GO:0006212) |
| 0.1 | 0.2 | GO:0003050 | regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050) |
| 0.1 | 1.8 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.1 | 0.5 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.1 | 0.2 | GO:0006533 | aspartate catabolic process(GO:0006533) |
| 0.1 | 1.0 | GO:0060732 | positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
| 0.1 | 0.4 | GO:2001270 | regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) |
| 0.1 | 0.1 | GO:2000547 | regulation of dendritic cell dendrite assembly(GO:2000547) |
| 0.1 | 0.5 | GO:0045586 | regulation of gamma-delta T cell differentiation(GO:0045586) |
| 0.1 | 0.6 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.1 | 1.6 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
| 0.1 | 0.7 | GO:0042574 | retinal metabolic process(GO:0042574) |
| 0.1 | 0.2 | GO:0014034 | neural crest cell fate commitment(GO:0014034) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) |
| 0.1 | 2.8 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.1 | 3.5 | GO:0007566 | embryo implantation(GO:0007566) |
| 0.1 | 2.6 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.1 | 0.5 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 0.1 | 0.3 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.1 | 0.3 | GO:1901093 | regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094) |
| 0.1 | 5.1 | GO:0015909 | long-chain fatty acid transport(GO:0015909) |
| 0.1 | 0.3 | GO:0071934 | thiamine transmembrane transport(GO:0071934) |
| 0.1 | 0.4 | GO:0072734 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 0.1 | 0.6 | GO:0042268 | regulation of cytolysis(GO:0042268) |
| 0.1 | 0.4 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.1 | 0.7 | GO:0017182 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.1 | 2.2 | GO:0071470 | cellular response to osmotic stress(GO:0071470) |
| 0.1 | 0.3 | GO:1904016 | response to Thyroglobulin triiodothyronine(GO:1904016) |
| 0.1 | 0.2 | GO:0048478 | replication fork protection(GO:0048478) |
| 0.1 | 1.6 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.1 | 0.4 | GO:0006116 | NADH oxidation(GO:0006116) |
| 0.1 | 0.6 | GO:0060746 | maternal behavior(GO:0042711) parental behavior(GO:0060746) |
| 0.1 | 0.9 | GO:0032740 | positive regulation of interleukin-17 production(GO:0032740) |
| 0.1 | 0.4 | GO:0061624 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.1 | 0.1 | GO:0006772 | thiamine metabolic process(GO:0006772) |
| 0.1 | 0.5 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.1 | 1.3 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 0.3 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
| 0.1 | 0.2 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
| 0.1 | 0.8 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.1 | 0.5 | GO:0044821 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.1 | 0.1 | GO:0051126 | negative regulation of actin nucleation(GO:0051126) |
| 0.1 | 0.2 | GO:0032887 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 0.1 | 0.2 | GO:1990180 | tRNA 3'-trailer cleavage, endonucleolytic(GO:0034414) tRNA 3'-trailer cleavage(GO:0042779) mitochondrial tRNA 3'-end processing(GO:1990180) |
| 0.1 | 0.6 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 0.1 | 1.9 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.1 | 0.2 | GO:0060523 | prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) |
| 0.1 | 0.7 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.1 | 2.1 | GO:0022030 | cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030) |
| 0.1 | 0.2 | GO:0097272 | ammonia homeostasis(GO:0097272) |
| 0.1 | 1.6 | GO:0006700 | C21-steroid hormone biosynthetic process(GO:0006700) |
| 0.1 | 0.6 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.1 | 1.0 | GO:1901642 | nucleoside transmembrane transport(GO:1901642) |
| 0.1 | 1.8 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.1 | 5.5 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 0.1 | 1.7 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.1 | 0.2 | GO:0097475 | motor neuron migration(GO:0097475) |
| 0.1 | 0.9 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.1 | 0.4 | GO:0042262 | DNA protection(GO:0042262) |
| 0.1 | 0.3 | GO:0009804 | coumarin metabolic process(GO:0009804) flavone metabolic process(GO:0051552) |
| 0.1 | 0.5 | GO:0042074 | cell migration involved in gastrulation(GO:0042074) |
| 0.1 | 0.9 | GO:0070266 | necroptotic process(GO:0070266) |
| 0.1 | 0.9 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 0.0 | 0.3 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.0 | 0.2 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.0 | 1.5 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 0.2 | GO:0008215 | spermine metabolic process(GO:0008215) |
| 0.0 | 0.2 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 0.0 | 0.9 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 0.0 | 0.7 | GO:0015871 | choline transport(GO:0015871) |
| 0.0 | 0.6 | GO:0043031 | negative regulation of macrophage activation(GO:0043031) |
| 0.0 | 0.8 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.0 | 1.3 | GO:0030517 | negative regulation of axon extension(GO:0030517) |
| 0.0 | 0.2 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
| 0.0 | 0.1 | GO:1904579 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) |
| 0.0 | 0.2 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.0 | 2.3 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.0 | 0.4 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.0 | 0.2 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.0 | 0.1 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 0.0 | 0.4 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.0 | 0.3 | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) |
| 0.0 | 0.5 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.0 | 0.3 | GO:0001714 | endodermal cell fate specification(GO:0001714) |
| 0.0 | 0.1 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 0.0 | 1.3 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.3 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.0 | 0.1 | GO:1903516 | regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) regulation of single strand break repair(GO:1903516) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824) negative regulation of t-circle formation(GO:1904430) |
| 0.0 | 0.6 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.0 | 0.5 | GO:0060413 | atrial septum morphogenesis(GO:0060413) |
| 0.0 | 0.6 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 1.3 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.0 | 0.7 | GO:0035751 | regulation of lysosomal lumen pH(GO:0035751) |
| 0.0 | 0.4 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 0.0 | 1.7 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.1 | GO:0086021 | SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) |
| 0.0 | 1.4 | GO:0044364 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.0 | 0.4 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
| 0.0 | 0.5 | GO:0043562 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 0.1 | GO:0051182 | coenzyme transport(GO:0051182) |
| 0.0 | 0.2 | GO:0032972 | regulation of muscle filament sliding speed(GO:0032972) |
| 0.0 | 3.3 | GO:0008344 | adult locomotory behavior(GO:0008344) |
| 0.0 | 0.4 | GO:1900165 | negative regulation of interleukin-6 secretion(GO:1900165) |
| 0.0 | 0.3 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 0.0 | 0.7 | GO:1903580 | positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580) |
| 0.0 | 2.3 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
| 0.0 | 0.1 | GO:0090135 | actin filament branching(GO:0090135) |
| 0.0 | 0.6 | GO:0023058 | adaptation of signaling pathway(GO:0023058) |
| 0.0 | 0.5 | GO:0043622 | cortical microtubule organization(GO:0043622) |
| 0.0 | 0.2 | GO:0060736 | prostate gland growth(GO:0060736) |
| 0.0 | 0.4 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.0 | 0.6 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.0 | 0.8 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.0 | 0.5 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 0.4 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.0 | 1.1 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.9 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.0 | 0.2 | GO:0010886 | positive regulation of cholesterol storage(GO:0010886) |
| 0.0 | 0.1 | GO:0036166 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
| 0.0 | 0.3 | GO:0007070 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
| 0.0 | 0.2 | GO:0060677 | ureteric bud elongation(GO:0060677) |
| 0.0 | 0.2 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.0 | 0.4 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.0 | 1.3 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.0 | 0.4 | GO:0044062 | regulation of excretion(GO:0044062) |
| 0.0 | 0.5 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.0 | 0.3 | GO:0007207 | phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.0 | 0.1 | GO:0090037 | positive regulation of protein kinase C signaling(GO:0090037) |
| 0.0 | 0.1 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 0.0 | 0.6 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.0 | 0.5 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.0 | 0.0 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.0 | 0.5 | GO:0002281 | macrophage activation involved in immune response(GO:0002281) |
| 0.0 | 0.3 | GO:0006167 | AMP biosynthetic process(GO:0006167) |
| 0.0 | 0.2 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) |
| 0.0 | 0.8 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.0 | 1.5 | GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) |
| 0.0 | 0.7 | GO:0042104 | positive regulation of activated T cell proliferation(GO:0042104) |
| 0.0 | 0.4 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.0 | 1.0 | GO:0032570 | response to progesterone(GO:0032570) |
| 0.0 | 0.2 | GO:0010819 | regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820) |
| 0.0 | 0.5 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.0 | 0.5 | GO:0035909 | aorta morphogenesis(GO:0035909) |
| 0.0 | 0.5 | GO:0071451 | cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) |
| 0.0 | 0.7 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 0.1 | GO:0006781 | succinyl-CoA pathway(GO:0006781) |
| 0.0 | 0.2 | GO:2000234 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.0 | 0.3 | GO:0045591 | positive regulation of regulatory T cell differentiation(GO:0045591) |
| 0.0 | 0.3 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 0.0 | 0.3 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.0 | 1.7 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.0 | 0.2 | GO:0032071 | regulation of endodeoxyribonuclease activity(GO:0032071) |
| 0.0 | 0.4 | GO:0045943 | positive regulation of transcription from RNA polymerase I promoter(GO:0045943) |
| 0.0 | 2.5 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
| 0.0 | 0.3 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.0 | 4.0 | GO:0031424 | keratinization(GO:0031424) |
| 0.0 | 0.2 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.0 | 0.1 | GO:2000563 | positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563) |
| 0.0 | 0.3 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 0.5 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 1.3 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
| 0.0 | 1.1 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
| 0.0 | 0.3 | GO:0051024 | positive regulation of immunoglobulin secretion(GO:0051024) |
| 0.0 | 0.3 | GO:0034770 | histone H4-K20 methylation(GO:0034770) |
| 0.0 | 0.2 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.0 | 0.7 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 0.0 | 0.5 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.3 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.0 | 0.1 | GO:0050902 | leukocyte adhesive activation(GO:0050902) |
| 0.0 | 0.2 | GO:1904894 | positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894) |
| 0.0 | 0.3 | GO:0070193 | synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193) |
| 0.0 | 0.6 | GO:0014046 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.0 | 0.5 | GO:0018027 | peptidyl-lysine dimethylation(GO:0018027) |
| 0.0 | 0.4 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.0 | 2.0 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
| 0.0 | 0.1 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.0 | 0.9 | GO:0048753 | melanosome organization(GO:0032438) pigment granule organization(GO:0048753) |
| 0.0 | 0.4 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 0.1 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.0 | 0.2 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) |
| 0.0 | 1.0 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.0 | 1.4 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.0 | 1.0 | GO:0035987 | endodermal cell differentiation(GO:0035987) |
| 0.0 | 0.1 | GO:0043313 | regulation of neutrophil degranulation(GO:0043313) |
| 0.0 | 0.7 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 0.0 | 0.3 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 1.1 | GO:0042509 | regulation of tyrosine phosphorylation of STAT protein(GO:0042509) |
| 0.0 | 0.0 | GO:0021897 | forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) |
| 0.0 | 0.6 | GO:0090303 | positive regulation of wound healing(GO:0090303) |
| 0.0 | 0.1 | GO:0043605 | allantoin metabolic process(GO:0000255) cellular amide catabolic process(GO:0043605) |
| 0.0 | 0.9 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.4 | GO:0031063 | regulation of histone deacetylation(GO:0031063) |
| 0.0 | 0.6 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
| 0.0 | 0.3 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.0 | 0.1 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 0.0 | 0.4 | GO:0030216 | keratinocyte differentiation(GO:0030216) |
| 0.0 | 0.5 | GO:0071347 | cellular response to interleukin-1(GO:0071347) |
| 0.0 | 0.3 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 0.2 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.0 | 0.2 | GO:0090043 | tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043) |
| 0.0 | 0.3 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 0.5 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.0 | 0.4 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.0 | 0.6 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.0 | 2.1 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.0 | 2.6 | GO:0038096 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096) |
| 0.0 | 0.0 | GO:2000077 | negative regulation of type B pancreatic cell development(GO:2000077) |
| 0.0 | 0.4 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.0 | 0.7 | GO:0001954 | positive regulation of cell-matrix adhesion(GO:0001954) |
| 0.0 | 0.9 | GO:0042733 | embryonic digit morphogenesis(GO:0042733) |
| 0.0 | 0.3 | GO:0001881 | receptor recycling(GO:0001881) |
| 0.0 | 0.1 | GO:0061622 | glycolytic process through glucose-1-phosphate(GO:0061622) |
| 0.0 | 0.2 | GO:0006105 | succinate metabolic process(GO:0006105) |
| 0.0 | 0.9 | GO:0090307 | mitotic spindle assembly(GO:0090307) |
| 0.0 | 0.2 | GO:1904871 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 0.0 | 0.2 | GO:2000678 | negative regulation of transcription regulatory region DNA binding(GO:2000678) |
| 0.0 | 0.1 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
| 0.0 | 2.7 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
| 0.0 | 0.1 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.0 | 0.0 | GO:0071169 | establishment of protein localization to chromatin(GO:0071169) |
| 0.0 | 1.5 | GO:0030308 | negative regulation of cell growth(GO:0030308) |
| 0.0 | 2.5 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.0 | 1.1 | GO:0043280 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280) |
| 0.0 | 0.6 | GO:0050994 | regulation of lipid catabolic process(GO:0050994) |
| 0.0 | 0.3 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.2 | GO:0048742 | regulation of skeletal muscle fiber development(GO:0048742) |
| 0.0 | 0.1 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.0 | 0.2 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.0 | 0.4 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
| 0.0 | 0.0 | GO:1903576 | 'de novo' UMP biosynthetic process(GO:0044205) response to L-arginine(GO:1903576) |
| 0.0 | 0.1 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
| 0.0 | 0.1 | GO:0019471 | 4-hydroxyproline metabolic process(GO:0019471) |
| 0.0 | 0.2 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
| 0.0 | 0.6 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
| 0.0 | 0.2 | GO:0046135 | pyrimidine nucleoside catabolic process(GO:0046135) |
| 0.0 | 0.1 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.0 | 0.1 | GO:0010642 | negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642) |
| 0.0 | 0.7 | GO:0035176 | social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
| 0.0 | 0.1 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.0 | 0.1 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.0 | 0.3 | GO:0048599 | oocyte development(GO:0048599) |
| 0.0 | 0.6 | GO:0045604 | regulation of epidermal cell differentiation(GO:0045604) |
| 0.0 | 0.2 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 0.3 | GO:0008038 | neuron recognition(GO:0008038) |
| 0.0 | 0.2 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.0 | 0.3 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.0 | 1.0 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.4 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 0.0 | 0.3 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 16.7 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 1.3 | 14.7 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.9 | 2.6 | GO:0036117 | hyaluranon cable(GO:0036117) |
| 0.8 | 2.5 | GO:0005760 | gamma DNA polymerase complex(GO:0005760) |
| 0.8 | 6.8 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.6 | 2.5 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
| 0.6 | 11.0 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.5 | 1.5 | GO:0005606 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
| 0.5 | 3.0 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 0.5 | 1.9 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.4 | 1.3 | GO:1905103 | integral component of lysosomal membrane(GO:1905103) |
| 0.4 | 1.3 | GO:1990666 | PCSK9-LDLR complex(GO:1990666) |
| 0.4 | 8.8 | GO:0005861 | troponin complex(GO:0005861) |
| 0.4 | 1.2 | GO:0033150 | cytoskeletal calyx(GO:0033150) |
| 0.4 | 2.2 | GO:0002081 | outer acrosomal membrane(GO:0002081) |
| 0.3 | 7.8 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.3 | 1.2 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.3 | 0.9 | GO:0036284 | tubulobulbar complex(GO:0036284) |
| 0.3 | 0.9 | GO:0033593 | BRCA2-MAGE-D1 complex(GO:0033593) |
| 0.3 | 2.3 | GO:1990745 | EARP complex(GO:1990745) |
| 0.3 | 4.2 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.3 | 1.1 | GO:0000811 | GINS complex(GO:0000811) |
| 0.3 | 1.0 | GO:0097229 | sperm end piece(GO:0097229) |
| 0.2 | 1.0 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
| 0.2 | 2.3 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.2 | 0.7 | GO:0042565 | RNA nuclear export complex(GO:0042565) |
| 0.2 | 0.7 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.2 | 2.0 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.2 | 1.0 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.2 | 0.7 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.2 | 1.2 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 0.2 | 1.0 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.2 | 1.4 | GO:1990630 | IRE1-RACK1-PP2A complex(GO:1990630) |
| 0.1 | 0.4 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.1 | 0.4 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 0.1 | 2.1 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.1 | 0.9 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.1 | 0.4 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.1 | 0.4 | GO:0002079 | inner acrosomal membrane(GO:0002079) |
| 0.1 | 0.8 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.1 | 2.0 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 0.1 | GO:0030128 | clathrin coat of endocytic vesicle(GO:0030128) |
| 0.1 | 1.5 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 0.8 | GO:0032021 | NELF complex(GO:0032021) |
| 0.1 | 2.5 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 3.1 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 2.7 | GO:0042627 | chylomicron(GO:0042627) |
| 0.1 | 0.7 | GO:0000801 | central element(GO:0000801) |
| 0.1 | 0.6 | GO:1990393 | 3M complex(GO:1990393) |
| 0.1 | 1.1 | GO:0005638 | lamin filament(GO:0005638) |
| 0.1 | 0.9 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.1 | 1.5 | GO:0000800 | lateral element(GO:0000800) |
| 0.1 | 1.6 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.1 | 1.1 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.1 | 1.4 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.1 | 1.1 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.1 | 0.3 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.1 | 0.3 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.1 | 2.0 | GO:0035859 | Seh1-associated complex(GO:0035859) |
| 0.1 | 2.9 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.1 | 0.9 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 0.8 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 1.7 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.1 | 2.5 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.1 | 2.3 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.1 | 0.3 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 0.1 | 2.3 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.1 | 1.7 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 0.5 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.1 | 0.5 | GO:0042825 | TAP complex(GO:0042825) |
| 0.1 | 1.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.1 | 1.5 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.1 | 0.5 | GO:0097451 | glial limiting end-foot(GO:0097451) |
| 0.1 | 1.0 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.1 | 0.2 | GO:0010370 | perinucleolar chromocenter(GO:0010370) |
| 0.1 | 3.3 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 0.8 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.1 | 0.3 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.1 | 0.7 | GO:0097486 | multivesicular body lumen(GO:0097486) |
| 0.1 | 0.5 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.1 | 0.2 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.1 | 0.6 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.1 | 2.4 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.1 | 0.6 | GO:0070449 | elongin complex(GO:0070449) |
| 0.1 | 0.4 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.0 | 0.4 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.0 | 1.3 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.0 | 0.3 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.0 | 0.2 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 0.2 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.0 | 0.6 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.0 | 6.0 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 4.1 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.4 | GO:0070522 | ERCC4-ERCC1 complex(GO:0070522) |
| 0.0 | 1.1 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 0.5 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.0 | 0.3 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.0 | 0.2 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 0.0 | 5.4 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 0.5 | GO:0030681 | multimeric ribonuclease P complex(GO:0030681) |
| 0.0 | 1.2 | GO:0000795 | synaptonemal complex(GO:0000795) |
| 0.0 | 0.6 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.0 | 0.5 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 0.0 | 0.6 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 0.0 | 0.3 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.0 | 1.0 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 0.3 | GO:0000243 | commitment complex(GO:0000243) |
| 0.0 | 0.7 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 0.8 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 6.0 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.1 | GO:0071159 | NF-kappaB complex(GO:0071159) |
| 0.0 | 0.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 1.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.1 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.0 | 0.1 | GO:0060342 | photoreceptor inner segment membrane(GO:0060342) |
| 0.0 | 0.1 | GO:0043203 | axon hillock(GO:0043203) |
| 0.0 | 1.9 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.3 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.0 | 0.3 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.0 | 3.6 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 1.8 | GO:0098636 | protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 0.7 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 3.2 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 1.1 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.0 | 0.2 | GO:0044218 | other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
| 0.0 | 5.1 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.8 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.0 | 0.2 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 0.5 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.0 | 5.4 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.3 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.0 | 0.4 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 0.3 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.0 | 0.4 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.0 | 0.2 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.0 | 0.3 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.0 | 2.1 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.0 | 0.3 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 2.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 1.8 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.1 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.0 | 14.2 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.6 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 1.0 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.2 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.0 | 0.1 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.0 | 0.1 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.0 | 0.3 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.0 | 0.2 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.0 | 0.5 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 1.2 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 6.5 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.3 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.3 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.0 | 3.3 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 1.8 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 5.8 | GO:0034774 | secretory granule lumen(GO:0034774) |
| 0.0 | 0.1 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.0 | 0.3 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 0.1 | GO:1990879 | CST complex(GO:1990879) |
| 0.0 | 0.6 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 0.5 | GO:0032432 | actin filament bundle(GO:0032432) |
| 0.0 | 0.8 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 2.1 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 2.0 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.2 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 0.0 | 0.1 | GO:0045179 | apical cortex(GO:0045179) |
| 0.0 | 0.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.0 | 0.2 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.7 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 0.1 | GO:0002169 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 0.0 | 0.5 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.0 | 0.1 | GO:0070187 | telosome(GO:0070187) |
| 0.0 | 0.8 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.3 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.5 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.6 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.0 | 0.4 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 0.2 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.2 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 0.0 | 1.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.1 | GO:0042641 | actomyosin(GO:0042641) |
| 0.0 | 4.8 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 0.3 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.1 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.7 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
| 1.3 | 7.9 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 1.0 | 6.3 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 1.0 | 5.2 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 1.0 | 3.0 | GO:0045550 | geranylgeranyl reductase activity(GO:0045550) |
| 0.8 | 2.5 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 0.8 | 11.3 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.7 | 3.6 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.7 | 3.4 | GO:0005502 | 11-cis retinal binding(GO:0005502) |
| 0.6 | 8.7 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.5 | 5.3 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.5 | 2.6 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.5 | 2.5 | GO:0016890 | site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890) |
| 0.5 | 1.4 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 0.4 | 2.7 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.4 | 1.3 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.4 | 1.3 | GO:0071885 | N-terminal protein N-methyltransferase activity(GO:0071885) |
| 0.4 | 1.7 | GO:0004992 | platelet activating factor receptor activity(GO:0004992) |
| 0.4 | 1.7 | GO:0004949 | cannabinoid receptor activity(GO:0004949) |
| 0.4 | 1.2 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.4 | 2.0 | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066) |
| 0.4 | 4.7 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.4 | 3.4 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.4 | 1.1 | GO:0015389 | pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389) |
| 0.4 | 1.9 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 0.4 | 1.1 | GO:0004750 | ribulose-phosphate 3-epimerase activity(GO:0004750) |
| 0.4 | 2.2 | GO:0016807 | cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004) |
| 0.4 | 1.1 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 0.4 | 14.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.4 | 2.5 | GO:0008481 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.3 | 7.3 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.3 | 1.7 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.3 | 2.0 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
| 0.3 | 6.3 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.3 | 1.3 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.3 | 2.6 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.3 | 3.9 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.3 | 1.0 | GO:0003941 | L-serine ammonia-lyase activity(GO:0003941) |
| 0.3 | 0.9 | GO:0080023 | 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023) |
| 0.3 | 1.9 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.3 | 2.8 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.3 | 1.4 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) |
| 0.3 | 1.3 | GO:1903135 | cupric ion binding(GO:1903135) |
| 0.3 | 3.1 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.3 | 1.3 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.3 | 7.0 | GO:0055103 | ligase regulator activity(GO:0055103) |
| 0.3 | 2.1 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.3 | 1.5 | GO:0042806 | fucose binding(GO:0042806) |
| 0.3 | 1.8 | GO:0047035 | testosterone dehydrogenase (NAD+) activity(GO:0047035) |
| 0.2 | 1.2 | GO:0030395 | lactose binding(GO:0030395) |
| 0.2 | 0.7 | GO:0090631 | pre-miRNA transporter activity(GO:0090631) |
| 0.2 | 1.2 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.2 | 4.1 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.2 | 0.7 | GO:0050698 | proteoglycan sulfotransferase activity(GO:0050698) |
| 0.2 | 0.9 | GO:0047493 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.2 | 2.5 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.2 | 0.9 | GO:0045569 | TRAIL binding(GO:0045569) |
| 0.2 | 6.4 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.2 | 0.9 | GO:0004991 | parathyroid hormone receptor activity(GO:0004991) |
| 0.2 | 0.6 | GO:0004452 | isopentenyl-diphosphate delta-isomerase activity(GO:0004452) |
| 0.2 | 0.9 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.2 | 2.1 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.2 | 0.6 | GO:0030249 | guanylate cyclase regulator activity(GO:0030249) |
| 0.2 | 1.4 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.2 | 0.6 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
| 0.2 | 1.6 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.2 | 0.8 | GO:0019797 | procollagen-proline 3-dioxygenase activity(GO:0019797) |
| 0.2 | 1.9 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.2 | 2.3 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.2 | 2.4 | GO:0019841 | retinol binding(GO:0019841) |
| 0.2 | 2.2 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
| 0.2 | 0.9 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.2 | 0.7 | GO:0016295 | oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) |
| 0.2 | 1.0 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.2 | 0.5 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
| 0.2 | 1.4 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.2 | 1.0 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
| 0.2 | 3.7 | GO:0043495 | protein anchor(GO:0043495) |
| 0.2 | 3.0 | GO:0008035 | high-density lipoprotein particle binding(GO:0008035) |
| 0.2 | 3.3 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.2 | 0.2 | GO:0005415 | nucleoside:sodium symporter activity(GO:0005415) |
| 0.2 | 1.3 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
| 0.2 | 0.6 | GO:0004853 | uroporphyrinogen decarboxylase activity(GO:0004853) |
| 0.2 | 0.5 | GO:0004608 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 0.2 | 0.8 | GO:0003896 | DNA primase activity(GO:0003896) |
| 0.2 | 0.5 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 0.2 | 3.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 5.4 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.1 | 0.6 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.1 | 0.6 | GO:0032089 | NACHT domain binding(GO:0032089) |
| 0.1 | 0.9 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 0.1 | 0.4 | GO:0032090 | Pyrin domain binding(GO:0032090) |
| 0.1 | 0.7 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.1 | 0.7 | GO:0004337 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 0.1 | 2.0 | GO:0043142 | single-stranded DNA-dependent ATPase activity(GO:0043142) |
| 0.1 | 1.7 | GO:0016713 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) |
| 0.1 | 0.4 | GO:0004611 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.1 | 1.1 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 0.1 | 0.6 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.1 | 1.3 | GO:0071253 | connexin binding(GO:0071253) |
| 0.1 | 0.8 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 0.1 | 2.0 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.1 | 0.9 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.1 | 1.1 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 1.4 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.1 | 18.8 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 1.1 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 0.1 | 1.1 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.1 | 1.0 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.1 | 0.8 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.1 | 0.8 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.1 | 1.1 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.1 | 0.3 | GO:0008670 | 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.1 | 1.0 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.1 | 2.6 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.1 | 0.3 | GO:0015403 | thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.1 | 1.5 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 0.4 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.1 | 2.1 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.1 | 0.4 | GO:0051733 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 0.1 | 0.8 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
| 0.1 | 0.7 | GO:0016900 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 0.1 | 1.5 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.1 | 0.5 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 0.1 | 1.6 | GO:0009881 | photoreceptor activity(GO:0009881) |
| 0.1 | 0.4 | GO:0002046 | opsin binding(GO:0002046) |
| 0.1 | 1.9 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.1 | 1.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.1 | 1.2 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.1 | 0.7 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.1 | 0.8 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.1 | 0.9 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
| 0.1 | 0.4 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.1 | 1.6 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.1 | 0.3 | GO:0042020 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 0.1 | 0.3 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.1 | 0.6 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.1 | 0.6 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.1 | 0.8 | GO:0055104 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 0.1 | 0.6 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.1 | 1.2 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.1 | 0.5 | GO:0089720 | caspase binding(GO:0089720) |
| 0.1 | 0.6 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.1 | 0.8 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.1 | 0.6 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.1 | 0.6 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 0.1 | 2.7 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.1 | 1.4 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.1 | 0.3 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
| 0.1 | 0.5 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.1 | 1.0 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 0.3 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.1 | 0.2 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.1 | 5.0 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 0.6 | GO:0070492 | oligosaccharide binding(GO:0070492) |
| 0.1 | 1.5 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.1 | 4.2 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 0.8 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.1 | 1.0 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.1 | 0.5 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.1 | 0.3 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.1 | 0.9 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 0.1 | 0.6 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.1 | 0.7 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.1 | 0.5 | GO:0038049 | transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) |
| 0.1 | 0.7 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 0.3 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.1 | 0.5 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.1 | 0.5 | GO:0004931 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.1 | 0.7 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 0.1 | 9.2 | GO:0002020 | protease binding(GO:0002020) |
| 0.1 | 2.1 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.1 | 0.2 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
| 0.1 | 0.3 | GO:0039552 | RIG-I binding(GO:0039552) |
| 0.1 | 0.5 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.1 | 0.2 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 0.1 | 0.3 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.1 | 0.2 | GO:0042781 | 3'-tRNA processing endoribonuclease activity(GO:0042781) |
| 0.1 | 1.0 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 1.2 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.1 | 0.4 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.1 | 0.4 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.1 | 0.8 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.1 | 0.4 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.1 | 1.1 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.1 | 0.2 | GO:0004419 | hydroxymethylglutaryl-CoA lyase activity(GO:0004419) |
| 0.1 | 0.5 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.1 | 0.4 | GO:0030614 | oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) |
| 0.1 | 0.8 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.0 | 1.4 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 4.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.5 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.0 | 0.2 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 0.0 | 1.0 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.3 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
| 0.0 | 0.2 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.0 | 2.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.5 | GO:0015321 | sodium-dependent phosphate transmembrane transporter activity(GO:0015321) |
| 0.0 | 0.3 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.0 | 0.4 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.0 | 1.2 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.0 | 1.8 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 0.3 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.0 | 1.2 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.0 | GO:0016635 | oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) |
| 0.0 | 0.4 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.0 | 0.7 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 0.7 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.0 | 0.2 | GO:0015204 | urea transmembrane transporter activity(GO:0015204) |
| 0.0 | 0.1 | GO:0086020 | gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) |
| 0.0 | 0.2 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.0 | 0.4 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.0 | 0.2 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.0 | 0.3 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.5 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.0 | 0.5 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.0 | 2.6 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.1 | GO:0001132 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
| 0.0 | 0.2 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.0 | 0.2 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.0 | 0.1 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.0 | 0.1 | GO:0031716 | calcitonin receptor binding(GO:0031716) |
| 0.0 | 0.6 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 0.2 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 1.0 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.3 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.0 | 0.7 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 1.2 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.5 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.3 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 0.0 | 0.3 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
| 0.0 | 0.6 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.0 | 0.4 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 0.9 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.4 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
| 0.0 | 0.9 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.0 | 0.9 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.1 | GO:0016918 | retinal binding(GO:0016918) |
| 0.0 | 0.5 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.0 | 0.2 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.0 | 0.3 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
| 0.0 | 0.7 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.0 | 0.4 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.0 | 12.7 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 2.4 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 0.7 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.0 | 2.3 | GO:1990782 | protein tyrosine kinase binding(GO:1990782) |
| 0.0 | 0.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.0 | 0.1 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.0 | 0.4 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.0 | 0.6 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.0 | 0.1 | GO:0043273 | CTPase activity(GO:0043273) |
| 0.0 | 1.0 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.2 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.0 | 0.6 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 1.7 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.1 | GO:0004335 | galactokinase activity(GO:0004335) |
| 0.0 | 0.1 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
| 0.0 | 0.8 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.5 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
| 0.0 | 0.7 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.7 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 1.5 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 0.6 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.7 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.1 | GO:0004802 | transketolase activity(GO:0004802) |
| 0.0 | 0.2 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.0 | 0.5 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.2 | GO:0010340 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 0.0 | 10.6 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.0 | 0.6 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.0 | 0.1 | GO:0004775 | succinate-CoA ligase (ADP-forming) activity(GO:0004775) |
| 0.0 | 0.1 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.0 | 0.8 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.1 | GO:0004961 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
| 0.0 | 0.1 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.0 | 1.1 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.1 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
| 0.0 | 0.1 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 0.0 | 0.9 | GO:0016645 | oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645) |
| 0.0 | 0.2 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.0 | 15.2 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 0.2 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.0 | 0.3 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.0 | 0.8 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.0 | 0.5 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.2 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.0 | 0.1 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.0 | 1.4 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 0.2 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.0 | 0.1 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 0.2 | GO:0071813 | lipoprotein particle binding(GO:0071813) protein-lipid complex binding(GO:0071814) |
| 0.0 | 0.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 0.3 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 0.1 | GO:0043813 | phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) |
| 0.0 | 0.1 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.0 | 0.7 | GO:0008066 | glutamate receptor activity(GO:0008066) |
| 0.0 | 0.5 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.4 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.0 | 0.7 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.2 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.3 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 0.1 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 0.1 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.0 | 0.6 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.2 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.0 | 0.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.2 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.0 | 0.3 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 0.8 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 0.9 | GO:0031072 | heat shock protein binding(GO:0031072) |
| 0.0 | 0.2 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 0.1 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
| 0.0 | 3.8 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.7 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 0.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.3 | GO:0031593 | polyubiquitin binding(GO:0031593) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 15.0 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.2 | 11.1 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.2 | 6.2 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.2 | 11.0 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 2.2 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 6.0 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.1 | 4.9 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.1 | 3.2 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.1 | 3.4 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.1 | 2.6 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 1.5 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 2.7 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 5.0 | PID ATR PATHWAY | ATR signaling pathway |
| 0.1 | 1.5 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 5.8 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 3.1 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.1 | 0.9 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.1 | 0.3 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.1 | 1.4 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 0.7 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 2.7 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 2.4 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.5 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.0 | 4.7 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 1.4 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 2.6 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 0.7 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.0 | 1.4 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 2.2 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.9 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.1 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 1.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.8 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 1.7 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 1.0 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.0 | 1.2 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 10.8 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.7 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 0.7 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 6.9 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.4 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 0.3 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 0.2 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.0 | 6.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 2.2 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.0 | 0.6 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.6 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.5 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.6 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.1 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.3 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.3 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.1 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.0 | 1.0 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 0.3 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 0.7 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.0 | 1.7 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.3 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 0.3 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.1 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.0 | 0.6 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 0.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.0 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 0.2 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.0 | 0.4 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.0 | 0.2 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 0.1 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 18.5 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.5 | 2.6 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.3 | 5.2 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.3 | 5.1 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.3 | 7.3 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.3 | 4.1 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.2 | 2.8 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.2 | 3.9 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.2 | 4.6 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.2 | 3.1 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.2 | 2.5 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.2 | 0.8 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.1 | 1.0 | REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
| 0.1 | 6.0 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 8.8 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 3.2 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 2.4 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.1 | 2.9 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.1 | 0.8 | REACTOME CTLA4 INHIBITORY SIGNALING | Genes involved in CTLA4 inhibitory signaling |
| 0.1 | 3.8 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.1 | 4.0 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 1.8 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.1 | 3.9 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 4.0 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 2.0 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.1 | 2.5 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.1 | 1.5 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 0.1 | 1.7 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 1.3 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.1 | 0.4 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.1 | 0.2 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 0.4 | REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
| 0.1 | 1.9 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 2.3 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 3.7 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 3.5 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.1 | 1.7 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.1 | 0.6 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 0.1 | 1.5 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.1 | 1.3 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 1.4 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.1 | 2.4 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 0.5 | REACTOME SIGNALING BY SCF KIT | Genes involved in Signaling by SCF-KIT |
| 0.1 | 1.1 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 0.7 | REACTOME OPSINS | Genes involved in Opsins |
| 0.1 | 0.8 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.1 | 2.0 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 1.3 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 2.2 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 1.0 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 5.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 1.0 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 0.6 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.0 | 2.2 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 0.5 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 1.1 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.9 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 1.0 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 1.3 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.4 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.6 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.0 | 1.2 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 3.8 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 8.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 6.0 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.0 | 0.4 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 1.4 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.8 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.0 | 2.2 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.8 | REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.1 | REACTOME RNA POL II TRANSCRIPTION | Genes involved in RNA Polymerase II Transcription |
| 0.0 | 0.3 | REACTOME INFLUENZA LIFE CYCLE | Genes involved in Influenza Life Cycle |
| 0.0 | 1.6 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.0 | 1.0 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 0.8 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.0 | 2.0 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.3 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 0.3 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.0 | 1.2 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.5 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 3.4 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.0 | 0.5 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 0.8 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.5 | REACTOME SIGNALING BY FGFR | Genes involved in Signaling by FGFR |
| 0.0 | 0.8 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.0 | 0.6 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 0.7 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 0.3 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.0 | 0.3 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.9 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.6 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 2.7 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.2 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 0.6 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.5 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.3 | REACTOME BASE EXCISION REPAIR | Genes involved in Base Excision Repair |
| 0.0 | 1.3 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.6 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.2 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.2 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.0 | 2.2 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.0 | 1.2 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.0 | 0.4 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.3 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 1.0 | REACTOME SIGNALING BY ERBB2 | Genes involved in Signaling by ERBB2 |
| 0.0 | 0.4 | REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 0.0 | 0.5 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 1.1 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.0 | 0.3 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.0 | 0.4 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.3 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |