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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for PKNOX1_TGIF2

Z-value: 0.51

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Transcription factors associated with PKNOX1_TGIF2

Gene Symbol Gene ID Gene Info
ENSG00000160199.15 PKNOX1
ENSG00000118707.11 TGIF2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF2hg38_v1_chr20_+_36574535_365746720.384.0e-02Click!
PKNOX1hg38_v1_chr21_+_42974510_429746490.038.8e-01Click!

Activity profile of PKNOX1_TGIF2 motif

Sorted Z-values of PKNOX1_TGIF2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX1_TGIF2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_+_3449413 1.05 ENST00000549253.5
TGFB induced factor homeobox 1
chr14_+_103121457 0.99 ENST00000333007.8
TNF alpha induced protein 2
chr6_+_32439866 0.54 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr19_+_7669080 0.49 ENST00000629642.1
resistin
chr3_+_52794768 0.47 ENST00000621946.4
ENST00000416872.6
ENST00000449956.2
inter-alpha-trypsin inhibitor heavy chain 3
chrX_-_135816265 0.45 ENST00000605791.7
cancer/testis antigen family 45 member A2
chr11_+_827545 0.45 ENST00000528542.6
calcium release activated channel regulator 2B
chr2_-_74552616 0.36 ENST00000409249.5
lysyl oxidase like 3
chr11_+_827913 0.36 ENST00000525077.2
calcium release activated channel regulator 2B
chr6_+_26124161 0.36 ENST00000377791.4
ENST00000602637.1
H2A clustered histone 6
chr21_-_32813679 0.35 ENST00000487113.1
ENST00000382373.4
chromosome 21 open reading frame 62
chr11_+_828150 0.34 ENST00000450448.5
calcium release activated channel regulator 2B
chr14_-_91732059 0.34 ENST00000553329.5
ENST00000256343.8
cation channel sperm associated auxiliary subunit beta
chr1_-_186680411 0.33 ENST00000367468.10
prostaglandin-endoperoxide synthase 2
chr11_+_6390439 0.32 ENST00000530395.1
ENST00000342245.9
ENST00000527275.5
sphingomyelin phosphodiesterase 1
chr18_-_56638427 0.32 ENST00000586262.5
ENST00000217515.11
thioredoxin like 1
chrX_-_135833541 0.31 ENST00000620885.1
cancer/testis antigen family 45 member A7
chr6_+_137867414 0.29 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr1_-_12616762 0.29 ENST00000464917.5
dehydrogenase/reductase 3
chr5_-_95284535 0.28 ENST00000515393.5
multiple C2 and transmembrane domain containing 1
chr4_-_82562240 0.28 ENST00000515780.6
transmembrane protein 150C
chrX_-_135850791 0.27 ENST00000611438.1
cancer/testis antigen family 45 member A8
chr17_+_78378633 0.27 ENST00000262764.11
ENST00000589689.5
ENST00000592043.5
ENST00000587356.1
phosphatidylglycerophosphate synthase 1
chr4_-_82561972 0.27 ENST00000454948.3
ENST00000449862.7
transmembrane protein 150C
chr19_+_11798514 0.26 ENST00000323169.10
ENST00000450087.1
zinc finger protein 491
chr5_+_42423433 0.26 ENST00000230882.9
growth hormone receptor
chr17_+_70075215 0.25 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
potassium inwardly rectifying channel subfamily J member 16
chr17_+_70075317 0.25 ENST00000589377.1
potassium inwardly rectifying channel subfamily J member 16
chrX_-_135764444 0.25 ENST00000597510.6
cancer/testis antigen family 45 member A3
chrX_-_135868069 0.25 ENST00000604569.1
cancer/testis antigen family 45 member A9
chr17_-_74361860 0.25 ENST00000375366.4
BTB domain containing 17
chr5_+_126423363 0.24 ENST00000285689.8
GRAM domain containing 2B
chr5_+_126423122 0.24 ENST00000515200.5
GRAM domain containing 2B
chr5_+_126423176 0.24 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr6_+_31706866 0.24 ENST00000375832.5
ENST00000503322.1
lymphocyte antigen 6 family member G6F
LY6G6F-LY6G6D readthrough
chr10_+_28677487 0.23 ENST00000375533.6
BMP and activin membrane bound inhibitor
chr3_-_142448004 0.23 ENST00000463916.5
5'-3' exoribonuclease 1
chr3_-_3179674 0.22 ENST00000424814.5
ENST00000450014.1
ENST00000231948.9
ENST00000432408.6
ENST00000639284.1
cereblon
chr16_-_57797764 0.22 ENST00000465878.6
ENST00000561524.5
kinesin family member C3
chr19_-_45322867 0.21 ENST00000221476.4
creatine kinase, M-type
chr14_+_100376398 0.21 ENST00000554998.5
ENST00000402312.8
ENST00000335290.10
ENST00000554175.5
WD repeat domain 25
chr18_+_3449817 0.21 ENST00000407501.6
TGFB induced factor homeobox 1
chr16_+_16390834 0.20 ENST00000344087.4
nuclear pore complex interacting protein family member A7
chr18_+_3449620 0.20 ENST00000405385.7
TGFB induced factor homeobox 1
chr16_+_50742059 0.20 ENST00000311559.13
ENST00000564326.5
ENST00000566206.5
ENST00000427738.8
CYLD lysine 63 deubiquitinase
chr4_-_47838095 0.20 ENST00000610355.4
ENST00000504584.1
corin, serine peptidase
chr6_+_137867241 0.20 ENST00000612899.5
ENST00000420009.5
TNF alpha induced protein 3
chr20_-_3084716 0.20 ENST00000380293.3
arginine vasopressin
chr7_+_80135694 0.20 ENST00000457358.7
G protein subunit alpha i1
chr18_+_3450036 0.20 ENST00000546979.5
ENST00000343820.10
ENST00000551402.1
ENST00000577543.5
TGFB induced factor homeobox 1
chr12_+_59596010 0.19 ENST00000547379.6
ENST00000552432.5
solute carrier family 16 member 7
chr6_-_32173109 0.19 ENST00000395496.5
1-acylglycerol-3-phosphate O-acyltransferase 1
chr12_-_91004965 0.19 ENST00000261172.8
epiphycan
chr9_-_122227525 0.18 ENST00000373755.6
ENST00000373754.6
LIM homeobox 6
chr11_+_64291992 0.18 ENST00000394525.6
potassium two pore domain channel subfamily K member 4
chrX_-_15664798 0.18 ENST00000380342.4
collectrin, amino acid transport regulator
chr20_-_62427528 0.18 ENST00000252998.2
RBBP8 N-terminal like
chr19_-_12933680 0.18 ENST00000593021.1
ENST00000314606.9
ENST00000587981.1
ENST00000423140.6
phenylalanyl-tRNA synthetase subunit alpha
chr2_-_74553049 0.17 ENST00000409549.5
lysyl oxidase like 3
chr6_-_32953017 0.17 ENST00000395305.7
ENST00000374843.9
ENST00000395303.7
ENST00000429234.1
major histocompatibility complex, class II, DM alpha
novel protein
chr16_-_30445865 0.17 ENST00000478753.5
selenophosphate synthetase 2
chr1_+_74235377 0.17 ENST00000326637.8
TNNI3 interacting kinase
chr17_+_41237998 0.17 ENST00000254072.7
keratin associated protein 9-8
chr18_+_56651335 0.16 ENST00000589935.1
ENST00000254442.8
ENST00000357574.7
WD repeat domain 7
chr1_-_89126066 0.15 ENST00000370466.4
guanylate binding protein 2
chr18_+_56651385 0.15 ENST00000615645.4
WD repeat domain 7
chr2_+_105851748 0.15 ENST00000425756.1
ENST00000393349.2
NCK adaptor protein 2
chr19_-_48044037 0.15 ENST00000293255.3
calcium binding protein 5
chr2_-_216372432 0.15 ENST00000273067.5
membrane associated ring-CH-type finger 4
chr8_+_23288081 0.15 ENST00000265806.12
ENST00000519952.6
ENST00000518840.6
R3H domain and coiled-coil containing 1
chr16_+_21233672 0.15 ENST00000311620.7
ankyrin repeat and sterile alpha motif domain containing 4B
chr12_-_66803980 0.15 ENST00000539540.5
ENST00000540433.5
ENST00000541947.1
ENST00000538373.1
glutamate receptor interacting protein 1
chr2_-_202238558 0.15 ENST00000392244.7
ENST00000409181.1
ENST00000409712.5
ENST00000409498.6
ENST00000409368.5
ENST00000392246.7
ENST00000392245.5
small ubiquitin like modifier 1
chr4_+_48483324 0.14 ENST00000273861.5
solute carrier family 10 member 4
chr19_+_12610912 0.14 ENST00000446165.2
ENST00000343325.9
zinc finger protein 791
chr1_-_201112420 0.14 ENST00000362061.4
ENST00000681874.1
calcium voltage-gated channel subunit alpha1 S
chr1_+_207089233 0.14 ENST00000243611.9
ENST00000367076.7
complement component 4 binding protein beta
chr1_+_207089283 0.14 ENST00000391923.1
complement component 4 binding protein beta
chr14_-_21526391 0.14 ENST00000611430.4
spalt like transcription factor 2
chr20_+_18467382 0.13 ENST00000377603.5
RNA polymerase III subunit F
chr22_-_49825900 0.13 ENST00000404034.5
bromodomain containing 1
chr1_+_207088825 0.13 ENST00000367078.8
complement component 4 binding protein beta
chr1_-_201112451 0.13 ENST00000367338.7
calcium voltage-gated channel subunit alpha1 S
chr16_-_69384747 0.13 ENST00000566257.5
telomeric repeat binding factor 2
chr10_-_11532275 0.13 ENST00000277575.5
USP6 N-terminal like
chr7_+_74028127 0.13 ENST00000438880.5
ENST00000414324.5
ENST00000380562.8
ENST00000380575.8
ENST00000380584.8
ENST00000458204.5
ENST00000357036.9
ENST00000417091.5
ENST00000429192.5
ENST00000252034.12
ENST00000442310.5
ENST00000380553.8
ENST00000380576.9
ENST00000428787.5
ENST00000320399.10
elastin
chr1_+_207089195 0.13 ENST00000452902.6
complement component 4 binding protein beta
chr16_-_1379674 0.12 ENST00000402641.6
ENST00000248104.11
ENST00000674376.1
ENST00000397464.5
unk like zinc finger
chr13_+_24270681 0.12 ENST00000343003.10
ENST00000399949.6
spermatogenesis associated 13
chr15_+_24823625 0.12 ENST00000400100.5
ENST00000645002.1
ENST00000642807.1
small nuclear ribonucleoprotein polypeptide N
chr18_+_905103 0.12 ENST00000579794.1
adenylate cyclase activating polypeptide 1
chr1_+_156106698 0.12 ENST00000675667.1
lamin A/C
chr6_+_168441170 0.12 ENST00000356284.7
SPARC related modular calcium binding 2
chr1_-_145885826 0.12 ENST00000544626.2
ENST00000355594.9
ankyrin repeat domain 35
chr15_+_76931704 0.12 ENST00000320963.9
ENST00000394885.8
ENST00000394883.3
reticulocalbin 2
chr7_+_74028066 0.12 ENST00000431562.5
ENST00000320492.11
ENST00000438906.5
elastin
chr5_-_159208066 0.12 ENST00000519865.5
ENST00000521606.6
ring finger protein 145
chr1_+_23959109 0.12 ENST00000471915.5
proline rich nuclear receptor coactivator 2
chr21_-_42315336 0.12 ENST00000398431.2
ENST00000518498.3
trefoil factor 3
chr6_+_168441136 0.11 ENST00000354536.9
SPARC related modular calcium binding 2
chr14_+_103100144 0.11 ENST00000380069.7
exocyst complex component 3 like 4
chr10_+_92848461 0.11 ENST00000443748.6
ENST00000371543.5
ENST00000260762.10
exocyst complex component 6
chr7_+_39566366 0.11 ENST00000448268.5
ENST00000223273.7
ENST00000432096.2
YAE1 maturation factor of ABCE1
chr3_-_27722699 0.11 ENST00000461503.2
eomesodermin
chr12_-_91058016 0.11 ENST00000266719.4
keratocan
chr15_-_30991595 0.11 ENST00000435680.6
myotubularin related protein 10
chr1_-_211133945 0.11 ENST00000640044.1
ENST00000640566.1
potassium voltage-gated channel subfamily H member 1
chr2_-_179049986 0.11 ENST00000409284.1
ENST00000443758.6
ENST00000446116.5
coiled-coil domain containing 141
chr9_+_67859398 0.11 ENST00000620792.1
ankyrin repeat domain 20 family member A1
chr12_+_121210160 0.10 ENST00000542067.5
purinergic receptor P2X 4
chr2_-_202238462 0.10 ENST00000409205.5
small ubiquitin like modifier 1
chr3_-_27722316 0.10 ENST00000449599.4
eomesodermin
chr1_-_209651291 0.10 ENST00000391911.5
ENST00000415782.1
laminin subunit beta 3
chr16_+_30201057 0.10 ENST00000569485.5
sulfotransferase family 1A member 3
chrX_+_136648138 0.10 ENST00000370629.7
CD40 ligand
chr8_-_42207557 0.10 ENST00000220809.9
ENST00000429089.6
ENST00000519510.5
ENST00000429710.6
ENST00000524009.5
plasminogen activator, tissue type
chr22_+_38656627 0.10 ENST00000411557.5
ENST00000396811.6
ENST00000216029.7
ENST00000416285.5
chibby family member 1, beta catenin antagonist
chr16_+_50742037 0.09 ENST00000569418.5
CYLD lysine 63 deubiquitinase
chrX_+_136648214 0.09 ENST00000370628.2
CD40 ligand
chr9_-_83817632 0.09 ENST00000376365.7
ENST00000376371.7
G kinase anchoring protein 1
chr16_+_50742110 0.09 ENST00000566679.6
ENST00000564634.5
ENST00000398568.6
CYLD lysine 63 deubiquitinase
chr12_-_31729010 0.09 ENST00000537562.5
ENST00000537960.5
ENST00000281471.11
ENST00000536761.5
ENST00000542781.5
ENST00000457428.6
antagonist of mitotic exit network 1 homolog
chr17_-_35795592 0.09 ENST00000615136.4
ENST00000605424.6
ENST00000612672.1
matrix metallopeptidase 28
chr22_+_50508216 0.09 ENST00000420993.7
ENST00000395698.7
ENST00000395701.7
ENST00000523045.5
ENST00000299821.15
non-SMC condensin II complex subunit H2
chr3_+_37975773 0.09 ENST00000436654.1
CTD small phosphatase like
chr8_-_29263063 0.09 ENST00000524189.6
kinesin family member 13B
chr7_+_23597373 0.09 ENST00000307471.8
ENST00000409765.5
coiled-coil domain containing 126
chr5_-_173616588 0.09 ENST00000285908.5
ENST00000311086.9
ENST00000480951.1
biorientation of chromosomes in cell division 1
chr2_+_233760265 0.09 ENST00000305208.10
ENST00000360418.4
UDP glucuronosyltransferase family 1 member A1
chr15_+_68054308 0.09 ENST00000249636.11
protein inhibitor of activated STAT 1
chr1_+_161766282 0.09 ENST00000680688.1
activating transcription factor 6
chr17_+_8288637 0.09 ENST00000407006.8
ENST00000226105.11
ENST00000580434.5
ENST00000439238.3
RAN guanine nucleotide release factor
chr16_+_2537997 0.09 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
3-phosphoinositide dependent protein kinase 1
chr4_+_158672237 0.09 ENST00000682734.1
electron transfer flavoprotein dehydrogenase
chr11_-_101129806 0.09 ENST00000325455.10
ENST00000617858.4
ENST00000619228.2
progesterone receptor
chr17_-_8190154 0.08 ENST00000389017.6
BLOC-1 related complex subunit 6
chr1_-_247008042 0.08 ENST00000339986.8
ENST00000487338.6
zinc finger protein 695
chr18_+_3451647 0.08 ENST00000345133.9
ENST00000330513.10
ENST00000549546.5
TGFB induced factor homeobox 1
chr17_+_4143168 0.08 ENST00000577075.6
ENST00000301391.8
ENST00000575251.5
cytochrome b5 domain containing 2
chr4_+_113116676 0.08 ENST00000671971.1
ENST00000672240.1
ENST00000673240.1
ENST00000673363.1
ankyrin 2
chr17_-_73092657 0.08 ENST00000580557.5
ENST00000579732.5
ENST00000578620.1
ENST00000542342.6
ENST00000255559.7
ENST00000579018.5
solute carrier family 39 member 11
chr17_+_41226648 0.08 ENST00000377721.3
keratin associated protein 9-2
chr12_+_121210065 0.08 ENST00000359949.11
ENST00000337233.9
ENST00000538701.5
purinergic receptor P2X 4
chr6_+_138773747 0.08 ENST00000617445.5
coiled-coil domain containing 28A
chr8_-_22109381 0.08 ENST00000613958.1
ENST00000611621.2
nudix hydrolase 18
chr12_-_14961256 0.08 ENST00000541380.5
Rho GDP dissociation inhibitor beta
chr17_-_1516699 0.08 ENST00000320345.10
ENST00000406424.8
inositol polyphosphate-5-phosphatase K
chr16_-_70251894 0.08 ENST00000435634.3
exosome component 6
chr7_+_23598144 0.08 ENST00000410069.1
coiled-coil domain containing 126
chr9_-_33447553 0.07 ENST00000645858.1
ENST00000297991.6
aquaporin 3 (Gill blood group)
chr1_-_31919093 0.07 ENST00000602683.5
ENST00000470404.5
protein tyrosine phosphatase 4A2
chr18_+_3451585 0.07 ENST00000551541.5
TGFB induced factor homeobox 1
chr14_+_103100328 0.07 ENST00000559116.1
exocyst complex component 3 like 4
chr4_+_2418932 0.07 ENST00000635017.1
cilia and flagella associated protein 99
chr16_-_4734127 0.07 ENST00000592711.5
ENST00000590147.5
ENST00000592190.1
ENST00000589065.5
ENST00000585773.5
ENST00000592698.5
ENST00000586166.5
ENST00000304283.9
ENST00000586605.5
ENST00000592421.5
ENST00000450067.6
ankyrin repeat and sterile alpha motif domain containing 3
chr3_-_49689053 0.07 ENST00000449682.2
macrophage stimulating 1
chr18_+_904863 0.07 ENST00000450565.8
adenylate cyclase activating polypeptide 1
chr14_-_106811131 0.07 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr7_-_156893150 0.07 ENST00000353442.10
limb development membrane protein 1
chr11_-_84317296 0.07 ENST00000280241.12
ENST00000398301.6
discs large MAGUK scaffold protein 2
chr12_+_54854505 0.07 ENST00000308796.11
ENST00000619042.1
mucin like 1
chr7_+_38178318 0.06 ENST00000396013.5
ENST00000440144.5
ENST00000453225.5
ENST00000429075.1
STARD3 N-terminal like
chr12_+_121888751 0.06 ENST00000261817.6
ENST00000538613.5
ENST00000542602.1
ENST00000541212.6
proteasome 26S subunit, non-ATPase 9
chr4_+_165378998 0.06 ENST00000402744.9
carboxypeptidase E
chr6_-_109094819 0.06 ENST00000436639.6
sestrin 1
chr12_-_31326171 0.06 ENST00000542983.1
SIN3-HDAC complex associated factor
chr16_-_30558263 0.06 ENST00000252797.6
zinc finger protein 764
chr3_-_71360753 0.06 ENST00000648783.1
forkhead box P1
chr2_+_10420021 0.06 ENST00000422133.1
hippocalcin like 1
chrX_-_135296024 0.06 ENST00000370764.1
zinc finger protein 75D
chr2_+_70935919 0.06 ENST00000412314.5
ATPase H+ transporting V1 subunit B1
chr4_+_122732652 0.06 ENST00000542236.5
ENST00000314218.8
Bardet-Biedl syndrome 12
chr2_+_70935864 0.06 ENST00000234396.10
ENST00000454446.6
ATPase H+ transporting V1 subunit B1
chr3_+_49689531 0.06 ENST00000432042.5
ENST00000454491.5
ENST00000327697.11
ring finger protein 123
chr11_+_55811367 0.06 ENST00000625203.2
olfactory receptor family 5 subfamily L member 1
chr7_+_144312419 0.06 ENST00000641044.2
olfactory receptor family 2 subfamily A member 1
chrX_-_153673678 0.06 ENST00000370150.5
pregnancy up-regulated nonubiquitous CaM kinase
chr7_+_23597499 0.06 ENST00000448353.5
coiled-coil domain containing 126
chr8_-_18683932 0.06 ENST00000615573.4
pleckstrin and Sec7 domain containing 3
chr1_-_246566238 0.06 ENST00000366514.5
transcription factor B2, mitochondrial
chr9_-_127905313 0.06 ENST00000622357.5
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr8_-_18684033 0.06 ENST00000614430.3
pleckstrin and Sec7 domain containing 3
chr8_-_18684093 0.06 ENST00000428502.6
pleckstrin and Sec7 domain containing 3
chr15_+_57376497 0.06 ENST00000281282.6
cingulin like 1
chr11_+_125746272 0.06 ENST00000305738.10
ENST00000437148.2
prostate and testis expressed 1
chr2_+_197515565 0.06 ENST00000233892.8
ENST00000409916.5
MOB family member 4, phocein
chr19_-_12441012 0.06 ENST00000301547.10
zinc finger protein 443
chr16_-_30558356 0.06 ENST00000395091.3
zinc finger protein 764
chr6_+_30328889 0.06 ENST00000396547.5
ENST00000623385.3
tripartite motif containing 39
TRIM39-RPP21 readthrough
chr12_-_104138007 0.06 ENST00000551727.5
nuclear transcription factor Y subunit beta
chr13_+_27919993 0.06 ENST00000381033.5
pancreatic and duodenal homeobox 1
chr17_+_61399835 0.06 ENST00000240328.4
T-box transcription factor 2
chr7_+_64313943 0.05 ENST00000423484.3
zinc finger protein 736
chr10_-_46030585 0.05 ENST00000580070.5
ENST00000578454.5
ENST00000585056.5
ENST00000579039.2
ENST00000581486.6
nuclear receptor coactivator 4
chr3_+_49803212 0.05 ENST00000333323.6
inka box actin regulator 1
chr3_+_45594727 0.05 ENST00000273317.5
LIM domains containing 1
chrX_-_153673778 0.05 ENST00000340888.8
pregnancy up-regulated nonubiquitous CaM kinase
chr8_-_17895403 0.05 ENST00000381840.5
ENST00000398054.5
fibrinogen like 1
chr7_+_38178216 0.05 ENST00000009041.12
ENST00000434197.5
STARD3 N-terminal like
chr7_+_69967464 0.05 ENST00000664521.1
activator of transcription and developmental regulator AUTS2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.2 0.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.2 0.5 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.1 0.5 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.5 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.1 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 1.2 GO:0051601 exocyst localization(GO:0051601)
0.1 1.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.5 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 0.2 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.2 GO:0090273 regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.1 0.2 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.3 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.2 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.1 GO:1903824 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.3 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.1 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.2 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.2 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:0022012 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.2 GO:0032306 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.0 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.0 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.2 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.0 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) positive regulation of type B pancreatic cell development(GO:2000078)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 1.3 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.0 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.0 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0070187 telosome(GO:0070187)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.2 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.1 1.8 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha