Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
PLAGL1 | hg38_v1_chr6_-_144008364_144008388 | 0.60 | 5.1e-04 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.9 | 41.3 | GO:0031642 | negative regulation of myelination(GO:0031642) |
1.7 | 30.8 | GO:0016540 | protein autoprocessing(GO:0016540) |
1.0 | 26.7 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
2.4 | 26.4 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
0.9 | 25.5 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
0.3 | 24.5 | GO:0016126 | sterol biosynthetic process(GO:0016126) |
4.0 | 23.9 | GO:0006535 | cysteine biosynthetic process from serine(GO:0006535) |
0.5 | 22.5 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
1.9 | 22.3 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
0.6 | 21.9 | GO:0035767 | endothelial cell chemotaxis(GO:0035767) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 190.2 | GO:0005924 | cell-substrate adherens junction(GO:0005924) |
0.3 | 55.9 | GO:0030027 | lamellipodium(GO:0030027) |
0.2 | 41.2 | GO:0045121 | membrane raft(GO:0045121) |
1.2 | 31.3 | GO:0005922 | connexon complex(GO:0005922) |
0.3 | 29.8 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.1 | 29.5 | GO:0031968 | mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968) |
0.8 | 25.9 | GO:0005865 | striated muscle thin filament(GO:0005865) |
1.7 | 25.7 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.2 | 24.5 | GO:0031674 | I band(GO:0031674) |
0.3 | 24.0 | GO:0005604 | basement membrane(GO:0005604) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 170.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.2 | 65.9 | GO:0045296 | cadherin binding(GO:0045296) |
0.3 | 53.2 | GO:0005178 | integrin binding(GO:0005178) |
0.3 | 43.0 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.2 | 40.4 | GO:0051015 | actin filament binding(GO:0051015) |
0.3 | 36.1 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.2 | 32.6 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.3 | 30.2 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.6 | 27.9 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
1.4 | 26.1 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 123.0 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.8 | 54.6 | PID AURORA B PATHWAY | Aurora B signaling |
0.8 | 52.5 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
0.1 | 42.8 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
0.8 | 34.7 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
0.5 | 34.6 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
0.5 | 32.0 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.7 | 28.9 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
0.3 | 28.3 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.6 | 28.0 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 52.2 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
0.2 | 46.2 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.7 | 35.6 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
0.4 | 34.2 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
1.3 | 31.3 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
0.2 | 29.0 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
0.3 | 28.6 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
0.5 | 26.6 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
1.0 | 26.1 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.2 | 25.7 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |