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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for POU2F2_POU3F1

Z-value: 0.90

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Transcription factors associated with POU2F2_POU3F1

Gene Symbol Gene ID Gene Info
ENSG00000028277.21 POU2F2
ENSG00000185668.8 POU3F1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F2hg38_v1_chr19_-_42132391_421324550.346.6e-02Click!
POU3F1hg38_v1_chr1_-_38046785_380468020.125.2e-01Click!

Activity profile of POU2F2_POU3F1 motif

Sorted Z-values of POU2F2_POU3F1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_26124161 2.42 ENST00000377791.4
ENST00000602637.1
H2A clustered histone 6
chr3_+_63652663 2.41 ENST00000343837.8
ENST00000469440.5
sentan, cilia apical structure protein
chr6_-_26123910 2.40 ENST00000314332.5
ENST00000396984.1
H2B clustered histone 4
chr6_+_52420992 2.35 ENST00000636954.1
ENST00000636566.1
ENST00000638075.1
EF-hand domain containing 1
chr6_-_27132750 2.30 ENST00000607124.1
ENST00000339812.3
H2B clustered histone 11
chr1_-_149886652 2.23 ENST00000369155.3
H2B clustered histone 21
chr1_-_183653307 2.20 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr6_-_26216673 2.07 ENST00000541790.3
H2B clustered histone 8
chr9_-_72953047 2.02 ENST00000297785.8
ENST00000376939.5
aldehyde dehydrogenase 1 family member A1
chr14_-_106470788 1.89 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr1_-_228457855 1.86 ENST00000366695.3
H2A.W histone
chr6_+_26216928 1.86 ENST00000303910.4
H2A clustered histone 8
chr6_+_27133032 1.70 ENST00000359193.3
H2A clustered histone 11
chrX_-_48919015 1.68 ENST00000376509.4
Pim-2 proto-oncogene, serine/threonine kinase
chr1_-_149842736 1.54 ENST00000369159.2
H2A clustered histone 18
chr1_+_149851053 1.53 ENST00000607355.2
H2A clustered histone 19
chr1_+_149886906 1.51 ENST00000331380.4
H2A clustered histone 20
chr6_+_27147094 1.43 ENST00000377459.3
H2A clustered histone 12
chr9_+_133459965 1.33 ENST00000540581.5
ENST00000542192.5
ENST00000291722.11
ENST00000316948.9
calcium channel flower domain containing 1
chr6_+_27865308 1.30 ENST00000613174.2
H2A clustered histone 16
chr19_-_43619591 1.27 ENST00000598676.1
ENST00000300811.8
zinc finger protein 428
chr15_-_19988117 1.23 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr2_-_238239958 1.16 ENST00000409182.1
ENST00000409002.7
ENST00000450098.1
ENST00000409356.1
ENST00000272937.10
ENST00000409160.7
ENST00000409574.1
hes family bHLH transcription factor 6
chr11_-_5227063 1.15 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr12_+_48904116 1.15 ENST00000552942.5
ENST00000320516.5
coiled-coil domain containing 65
chr6_+_26183750 1.14 ENST00000614097.3
H2B clustered histone 6
chr6_-_27893175 1.08 ENST00000359611.4
H2A clustered histone 17
chr9_-_81688354 1.05 ENST00000418319.5
TLE family member 1, transcriptional corepressor
chr17_+_74737211 1.04 ENST00000392612.7
ENST00000392610.5
RAB37, member RAS oncogene family
chr18_-_55422492 1.04 ENST00000561992.5
ENST00000630712.2
transcription factor 4
chr19_-_45584810 1.04 ENST00000323060.3
outer mitochondrial membrane lipid metabolism regulator OPA3
chr9_+_89605004 0.99 ENST00000252506.11
ENST00000375769.1
growth arrest and DNA damage inducible gamma
chr1_+_103655760 0.98 ENST00000370083.9
amylase alpha 1A
chr1_-_149812359 0.98 ENST00000369167.2
ENST00000545683.1
H2B clustered histone 18
chr17_-_75779758 0.97 ENST00000592643.5
ENST00000591890.5
ENST00000587171.1
ENST00000254810.8
ENST00000589599.5
H3.3 histone B
chr6_-_27146841 0.97 ENST00000356950.2
H2B clustered histone 12
chr11_+_27040725 0.97 ENST00000529202.5
ENST00000263182.8
gamma-butyrobetaine hydroxylase 1
chr17_+_74737238 0.95 ENST00000392613.10
ENST00000613645.1
RAB37, member RAS oncogene family
chr16_+_2969548 0.92 ENST00000572687.1
progestin and adipoQ receptor family member 4
chr11_+_27041313 0.92 ENST00000528583.5
gamma-butyrobetaine hydroxylase 1
chr16_-_21303036 0.90 ENST00000219599.8
ENST00000576703.5
crystallin mu
chr18_-_55422306 0.89 ENST00000566777.5
ENST00000626584.2
transcription factor 4
chr16_-_30096170 0.88 ENST00000566134.5
ENST00000565110.5
ENST00000398841.6
ENST00000398838.8
yippee like 3
chr12_-_68302872 0.86 ENST00000539972.5
Mdm1 nuclear protein
chr17_+_70104848 0.86 ENST00000392670.5
potassium inwardly rectifying channel subfamily J member 16
chr19_-_14884761 0.85 ENST00000642123.1
olfactory receptor family 7 subfamily A member 17
chr15_+_83447328 0.82 ENST00000427482.7
SH3 domain containing GRB2 like 3, endophilin A3
chr12_-_7092422 0.81 ENST00000543835.5
ENST00000647956.2
ENST00000535233.6
complement C1r
chr14_+_64540734 0.80 ENST00000247207.7
heat shock protein family A (Hsp70) member 2
chr15_+_83447411 0.79 ENST00000324537.5
SH3 domain containing GRB2 like 3, endophilin A3
chr8_+_55879818 0.78 ENST00000520220.6
ENST00000519728.6
LYN proto-oncogene, Src family tyrosine kinase
chr1_+_59310071 0.78 ENST00000371212.5
FGGY carbohydrate kinase domain containing
chr6_+_27893411 0.78 ENST00000616182.2
H2B clustered histone 17
chr16_+_2969307 0.78 ENST00000576565.1
ENST00000318782.9
progestin and adipoQ receptor family member 4
chr16_+_2969270 0.77 ENST00000293978.12
progestin and adipoQ receptor family member 4
chr6_-_27807916 0.77 ENST00000377401.3
H2B clustered histone 13
chrX_-_24647300 0.77 ENST00000379144.7
phosphate cytidylyltransferase 1, choline, beta
chr19_-_17405554 0.74 ENST00000252593.7
bone marrow stromal cell antigen 2
chr1_+_61082398 0.74 ENST00000664149.1
nuclear factor I A
chr17_-_19748355 0.74 ENST00000494157.6
aldehyde dehydrogenase 3 family member A1
chr7_-_130441136 0.73 ENST00000675596.1
ENST00000676312.1
centrosomal protein 41
chr19_+_17226597 0.72 ENST00000597836.5
occludin/ELL domain containing 1
chr16_+_33009175 0.71 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr1_+_202010575 0.71 ENST00000367283.7
ENST00000367284.10
E74 like ETS transcription factor 3
chr11_+_27055215 0.71 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr1_-_154859841 0.70 ENST00000361147.8
potassium calcium-activated channel subfamily N member 3
chr2_-_210171402 0.70 ENST00000281772.14
KAT8 regulatory NSL complex subunit 1 like
chr19_+_17226662 0.69 ENST00000598068.5
occludin/ELL domain containing 1
chr3_-_112641128 0.69 ENST00000206423.8
coiled-coil domain containing 80
chr13_-_35855758 0.69 ENST00000615680.4
doublecortin like kinase 1
chr19_+_17226218 0.69 ENST00000601529.5
ENST00000215061.9
ENST00000600232.5
occludin/ELL domain containing 1
chrX_-_24647091 0.69 ENST00000356768.8
phosphate cytidylyltransferase 1, choline, beta
chr6_-_27814757 0.68 ENST00000333151.5
H2A clustered histone 14
chr6_+_26158115 0.67 ENST00000377777.5
ENST00000289316.2
H2B clustered histone 5
chr1_+_61081728 0.67 ENST00000371189.8
nuclear factor I A
chr3_-_112846856 0.66 ENST00000488794.5
CD200 receptor 1 like
chr11_+_120236635 0.66 ENST00000260264.8
POU class 2 homeobox 3
chr6_+_26272923 0.66 ENST00000377733.4
H2B clustered histone 10
chr9_-_113303271 0.65 ENST00000297894.5
ENST00000489339.2
ring finger protein 183
chr2_-_210171327 0.65 ENST00000418791.5
ENST00000452086.5
KAT8 regulatory NSL complex subunit 1 like
chr11_-_8594181 0.65 ENST00000358872.7
ENST00000454443.2
serine/threonine kinase 33
chr6_+_27815010 0.65 ENST00000621112.2
H2B clustered histone 14
chr16_+_19417875 0.64 ENST00000542583.7
transmembrane channel like 5
chr4_-_109302707 0.63 ENST00000642955.1
collagen type XXV alpha 1 chain
chr1_+_167329044 0.61 ENST00000367862.9
POU class 2 homeobox 1
chr6_-_81752671 0.59 ENST00000320172.11
ENST00000369754.7
ENST00000369756.3
terminal nucleotidyltransferase 5A
chr14_+_79279403 0.58 ENST00000281127.11
neurexin 3
chr12_+_48904105 0.58 ENST00000266984.9
coiled-coil domain containing 65
chr6_-_170291053 0.55 ENST00000366756.4
delta like canonical Notch ligand 1
chr17_-_19748285 0.54 ENST00000570414.1
ENST00000225740.11
aldehyde dehydrogenase 3 family member A1
chr2_+_96760857 0.54 ENST00000377075.3
cyclin and CBS domain divalent metal cation transport mediator 4
chr17_-_19748341 0.54 ENST00000395555.7
aldehyde dehydrogenase 3 family member A1
chr16_-_33845229 0.53 ENST00000569103.2
immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr18_+_46946821 0.51 ENST00000245121.9
ENST00000356157.12
katanin catalytic subunit A1 like 2
chr11_+_73308237 0.51 ENST00000263674.4
Rho guanine nucleotide exchange factor 17
chr1_-_5992407 0.51 ENST00000378156.9
ENST00000622020.4
nephrocystin 4
chr11_-_6030758 0.51 ENST00000641900.1
olfactory receptor family 56 subfamily A member 1
chr2_+_10721649 0.51 ENST00000381661.3
ATPase H+ transporting V1 subunit C2
chr11_+_537517 0.51 ENST00000270115.8
leucine rich repeat containing 56
chr2_+_10721623 0.50 ENST00000272238.9
ATPase H+ transporting V1 subunit C2
chr4_-_185812209 0.50 ENST00000393523.6
ENST00000393528.7
ENST00000449407.6
sorbin and SH3 domain containing 2
chr17_+_14301069 0.50 ENST00000360954.3
heparan sulfate-glucosamine 3-sulfotransferase 3B1
chr14_-_106389858 0.49 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr7_+_98211431 0.49 ENST00000609256.2
basic helix-loop-helix family member a15
chr14_-_106154113 0.48 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr3_-_112641292 0.48 ENST00000439685.6
coiled-coil domain containing 80
chr10_+_69451456 0.47 ENST00000373290.7
tetraspanin 15
chr16_-_11636357 0.47 ENST00000576334.1
ENST00000574848.5
lipopolysaccharide induced TNF factor
chr10_+_104353820 0.47 ENST00000369704.8
cilia and flagella associated protein 58
chr12_+_6944065 0.46 ENST00000540506.2
chromosome 12 open reading frame 57
chr14_-_106165730 0.46 ENST00000390604.2
immunoglobulin heavy variable 3-16 (non-functional)
chr6_+_26251607 0.46 ENST00000619466.2
H2B clustered histone 9
chr12_+_6943811 0.45 ENST00000544681.1
ENST00000537087.5
chromosome 12 open reading frame 57
chr19_-_19033480 0.45 ENST00000452918.7
ENST00000600377.1
ENST00000337018.10
SURP and G-patch domain containing 2
chr12_+_6944009 0.45 ENST00000229281.6
chromosome 12 open reading frame 57
chr4_-_86101922 0.43 ENST00000472236.5
ENST00000641881.1
mitogen-activated protein kinase 10
chr7_-_130440848 0.43 ENST00000675803.1
ENST00000223208.10
ENST00000343969.10
ENST00000471201.6
ENST00000675649.1
ENST00000675168.1
ENST00000469826.2
ENST00000334451.6
ENST00000675962.1
ENST00000675563.1
ENST00000480206.2
ENST00000489512.5
ENST00000676243.1
ENST00000674539.1
ENST00000675935.1
centrosomal protein 41
chr2_-_157325808 0.43 ENST00000410096.6
ENST00000420719.6
ENST00000409216.5
ENST00000419116.2
ermin
chr17_+_63773863 0.42 ENST00000578681.5
ENST00000583590.5
DEAD-box helicase 42
chr7_+_90709530 0.42 ENST00000406263.5
cyclin dependent kinase 14
chr17_+_40015428 0.42 ENST00000394149.8
ENST00000225474.6
ENST00000331769.6
ENST00000394148.7
ENST00000577675.1
colony stimulating factor 3
chr12_-_55966018 0.41 ENST00000548803.5
ENST00000449260.6
ENST00000550447.5
ENST00000547137.5
ENST00000546543.5
ENST00000548747.6
ENST00000550464.5
premelanosome protein
chr11_+_112175526 0.41 ENST00000532612.5
ENST00000438022.5
beta-carotene oxygenase 2
chr21_-_10649835 0.41 ENST00000622028.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr1_+_228458095 0.41 ENST00000620438.1
H2B.U histone 1
chr17_+_20155989 0.41 ENST00000395530.6
ENST00000581399.6
ENST00000679819.1
sperm antigen with calponin homology and coiled-coil domains 1
chr1_-_23559490 0.40 ENST00000374561.6
inhibitor of DNA binding 3, HLH protein
chr6_-_26033609 0.40 ENST00000615868.2
H2A clustered histone 4
chr16_+_85611401 0.39 ENST00000405402.6
Gse1 coiled-coil protein
chr18_-_55585773 0.39 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
transcription factor 4
chr2_-_238288600 0.38 ENST00000254657.8
period circadian regulator 2
chr3_-_18425295 0.38 ENST00000338745.11
ENST00000450898.1
SATB homeobox 1
chr6_+_138773747 0.38 ENST00000617445.5
coiled-coil domain containing 28A
chr11_-_62591500 0.37 ENST00000476907.6
ENST00000278279.7
terminal uridylyl transferase 1, U6 snRNA-specific
chr11_-_62591554 0.37 ENST00000494385.1
ENST00000308436.11
terminal uridylyl transferase 1, U6 snRNA-specific
chr17_+_63774144 0.37 ENST00000389924.7
ENST00000359353.9
DEAD-box helicase 42
chr6_+_10585748 0.37 ENST00000265012.5
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr7_-_113087720 0.37 ENST00000297146.7
G protein-coupled receptor 85
chr16_-_19886133 0.36 ENST00000568214.1
ENST00000569479.5
G protein-coupled receptor class C group 5 member B
chr17_-_49764123 0.36 ENST00000240364.7
ENST00000506156.1
family with sequence similarity 117 member A
chr7_+_90709231 0.36 ENST00000446790.5
ENST00000265741.7
cyclin dependent kinase 14
chr4_-_73223082 0.35 ENST00000509867.6
ankyrin repeat domain 17
chr5_-_67196791 0.35 ENST00000256447.5
CD180 molecule
chr22_+_22431949 0.35 ENST00000390301.3
immunoglobulin lambda variable 1-36
chr1_-_201115372 0.34 ENST00000458416.2
achaete-scute family bHLH transcription factor 5
chrX_+_70455093 0.34 ENST00000542398.1
discs large MAGUK scaffold protein 3
chr6_+_27247690 0.34 ENST00000421826.6
ENST00000230582.8
serine protease 16
chr5_+_102808057 0.34 ENST00000684043.1
ENST00000682407.1
peptidylglycine alpha-amidating monooxygenase
chr4_-_86357722 0.34 ENST00000641341.1
ENST00000642038.1
ENST00000641116.1
ENST00000641767.1
ENST00000639242.1
ENST00000638313.1
mitogen-activated protein kinase 10
chr6_-_26043704 0.34 ENST00000615966.2
H2B clustered histone 3
chr18_-_55321640 0.34 ENST00000637169.2
transcription factor 4
chr4_-_25863537 0.33 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr10_-_102120246 0.33 ENST00000425280.2
LIM domain binding 1
chr11_+_112176364 0.33 ENST00000526088.5
ENST00000532593.5
ENST00000531169.5
beta-carotene oxygenase 2
chr12_-_31326171 0.33 ENST00000542983.1
SIN3-HDAC complex associated factor
chr17_+_40062810 0.33 ENST00000584985.5
ENST00000264637.8
thyroid hormone receptor alpha
chr14_-_106557465 0.33 ENST00000390625.3
immunoglobulin heavy variable 3-49
chr5_+_73813518 0.32 ENST00000296799.8
Rho guanine nucleotide exchange factor 28
chr1_-_156082412 0.32 ENST00000532414.3
mex-3 RNA binding family member A
chr14_-_106803221 0.32 ENST00000390636.2
immunoglobulin heavy variable 3-73
chr12_+_14774362 0.32 ENST00000544848.2
H2A.J histone
chr2_-_218002988 0.31 ENST00000682258.1
ENST00000446903.5
tensin 1
chr14_+_103107516 0.31 ENST00000560304.1
exocyst complex component 3 like 4
chr6_+_96562548 0.31 ENST00000541107.5
ENST00000326771.2
four and a half LIM domains 5
chr6_-_142945028 0.31 ENST00000012134.7
HIVEP zinc finger 2
chr7_-_120858066 0.31 ENST00000222747.8
tetraspanin 12
chr6_-_55875583 0.30 ENST00000370830.4
bone morphogenetic protein 5
chr15_-_40874216 0.30 ENST00000220507.5
ras homolog family member V
chr6_-_142945160 0.30 ENST00000367603.8
HIVEP zinc finger 2
chrX_+_81202066 0.29 ENST00000373212.6
SH3 domain binding glutamate rich protein like
chr5_+_36608146 0.29 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr11_-_62601818 0.29 ENST00000278823.7
metastasis associated 1 family member 2
chr18_-_63644250 0.29 ENST00000341074.10
ENST00000436264.1
serpin family B member 4
chr19_+_40799155 0.29 ENST00000303961.9
egl-9 family hypoxia inducible factor 2
chrX_-_64205680 0.28 ENST00000374869.8
APC membrane recruitment protein 1
chr15_-_64703199 0.28 ENST00000559753.1
ENST00000560258.6
ENST00000559912.2
ENST00000326005.10
ornithine decarboxylase antizyme 2
chr16_-_73048104 0.28 ENST00000268489.10
zinc finger homeobox 3
chr6_-_149484965 0.28 ENST00000409806.8
zinc finger CCCH-type containing 12D
chr5_-_19988179 0.27 ENST00000502796.5
ENST00000382275.6
ENST00000511273.1
cadherin 18
chr11_+_120240135 0.27 ENST00000543440.7
POU class 2 homeobox 3
chr7_-_100586119 0.27 ENST00000310300.11
leucine rich repeats and calponin homology domain containing 4
chr6_+_143677935 0.27 ENST00000440869.6
ENST00000367582.7
ENST00000451827.6
phosphatase and actin regulator 2
chr10_-_127892930 0.26 ENST00000368671.4
clarin 3
chrX_+_12975083 0.26 ENST00000451311.7
ENST00000380636.1
thymosin beta 4 X-linked
chr4_+_183905266 0.26 ENST00000308497.9
storkhead box 2
chr12_-_31326142 0.26 ENST00000337682.9
SIN3-HDAC complex associated factor
chr12_-_31326111 0.26 ENST00000539409.5
SIN3-HDAC complex associated factor
chr4_+_26320563 0.26 ENST00000361572.10
recombination signal binding protein for immunoglobulin kappa J region
chr6_+_26224192 0.26 ENST00000634733.1
H3 clustered histone 6
chr7_-_120858303 0.25 ENST00000415871.5
ENST00000430985.1
tetraspanin 12
chr5_+_76819022 0.25 ENST00000296677.5
F2R like trypsin receptor 1
chr20_+_34704336 0.25 ENST00000374809.6
ENST00000374810.8
ENST00000451665.5
tumor protein p53 inducible nuclear protein 2
chr18_-_77127935 0.25 ENST00000581878.5
myelin basic protein
chr19_-_40425982 0.25 ENST00000357949.5
SERTA domain containing 1
chr17_-_65561137 0.25 ENST00000580513.1
axin 2
chr6_-_35688935 0.24 ENST00000542713.1
FKBP prolyl isomerase 5
chr17_+_65137408 0.24 ENST00000443584.7
ENST00000449996.7
regulator of G protein signaling 9
chr7_-_44082464 0.24 ENST00000335195.10
ENST00000395831.7
ENST00000414235.5
ENST00000242248.10
ENST00000452049.1
DNA polymerase mu
chr6_+_148342759 0.23 ENST00000367467.8
SAM and SH3 domain containing 1
chr6_-_168079159 0.23 ENST00000283309.10
FERM domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0030185 nitric oxide transport(GO:0030185)
0.3 2.0 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 0.8 GO:0070662 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) mast cell proliferation(GO:0070662)
0.2 0.7 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.2 0.7 GO:0016108 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.2 2.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.5 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.2 0.5 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.2 1.4 GO:0021678 third ventricle development(GO:0021678)
0.2 0.5 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 1.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.4 GO:0051946 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.3 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.6 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.1 0.3 GO:0018032 protein amidation(GO:0018032)
0.1 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.4 GO:0019075 virus maturation(GO:0019075)
0.1 0.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.7 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.6 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.3 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.7 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.2 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.2 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.2 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.9 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.7 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.2 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.2 GO:2000690 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.3 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.2 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.0 0.5 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.4 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 2.5 GO:0007140 male meiosis(GO:0007140)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 1.0 GO:0072189 ureter development(GO:0072189)
0.0 1.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.3 GO:0009449 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 2.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.0 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.5 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.9 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.3 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.4 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 1.9 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0042323 positive regulation of nucleobase-containing compound transport(GO:0032241) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 1.8 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 1.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.1 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.2 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:1903998 regulation of eating behavior(GO:1903998)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.5 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.0 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.5 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.4 GO:0032438 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.0 0.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.0 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 2.7 GO:0065004 protein-DNA complex assembly(GO:0065004)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.0 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2 0.8 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.8 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.7 GO:0033269 internode region of axon(GO:0033269)
0.1 0.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.5 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 2.6 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 2.3 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 3.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.0 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 1.4 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 3.8 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 1.0 GO:0004556 alpha-amylase activity(GO:0004556)
0.3 1.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 0.8 GO:0019150 D-ribulokinase activity(GO:0019150)
0.2 0.9 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 1.2 GO:0030492 hemoglobin binding(GO:0030492)
0.2 3.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.9 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 1.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.3 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.3 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.6 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 2.2 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 1.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.8 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.0 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 3.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.8 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits