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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for POU3F3_POU3F4

Z-value: 0.91

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Transcription factors associated with POU3F3_POU3F4

Gene Symbol Gene ID Gene Info
ENSG00000198914.5 POU3F3
ENSG00000196767.9 POU3F4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU3F4hg38_v1_chrX_+_83508284_83508309-0.364.9e-02Click!
POU3F3hg38_v1_chr2_+_104854104_104854124-0.183.3e-01Click!

Activity profile of POU3F3_POU3F4 motif

Sorted Z-values of POU3F3_POU3F4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU3F3_POU3F4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_-_45378519 4.73 ENST00000558163.1
ENST00000396659.8
ENST00000675323.1
ENST00000558336.5
glycine amidinotransferase
chr1_+_103655760 4.72 ENST00000370083.9
amylase alpha 1A
chr1_+_103750406 4.63 ENST00000370079.3
amylase alpha 1C
chr1_+_103617427 4.30 ENST00000423678.2
ENST00000414303.7
amylase alpha 2A
chr1_-_103696209 4.18 ENST00000330330.10
amylase alpha 1B
chr1_+_103749898 3.74 ENST00000622339.5
amylase alpha 1C
chr12_+_109347903 3.57 ENST00000310903.9
myosin IH
chr1_+_103571077 3.17 ENST00000610648.1
amylase alpha 2B
chr4_-_16083695 3.06 ENST00000510224.5
prominin 1
chr4_-_16083714 3.04 ENST00000508167.5
prominin 1
chr19_+_735026 2.94 ENST00000592155.5
ENST00000590161.2
paralemmin
chr14_-_20802402 2.94 ENST00000412779.2
ribonuclease A family member 1, pancreatic
chr14_-_20802836 2.83 ENST00000397967.5
ENST00000555698.5
ENST00000397970.4
ENST00000340900.3
ribonuclease A family member 1, pancreatic
chr3_-_112846856 2.50 ENST00000488794.5
CD200 receptor 1 like
chr11_-_26572102 2.46 ENST00000455601.6
mucin 15, cell surface associated
chr12_+_48904116 2.39 ENST00000552942.5
ENST00000320516.5
coiled-coil domain containing 65
chr11_-_26572130 2.38 ENST00000527569.1
mucin 15, cell surface associated
chr18_-_27143024 2.22 ENST00000581714.5
carbohydrate sulfotransferase 9
chr3_-_112845950 2.15 ENST00000398214.5
CD200 receptor 1 like
chr9_+_34458752 2.11 ENST00000614641.4
ENST00000242317.9
ENST00000437363.5
dynein axonemal intermediate chain 1
chr5_+_140875299 2.00 ENST00000613593.1
ENST00000398631.3
protocadherin alpha 12
chr4_-_99352730 1.99 ENST00000510055.5
ENST00000515683.6
ENST00000511397.3
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr15_-_52295792 1.91 ENST00000261839.12
myosin VC
chrX_+_41688967 1.85 ENST00000378142.9
G protein-coupled receptor 34
chr1_+_59310071 1.74 ENST00000371212.5
FGGY carbohydrate kinase domain containing
chr1_-_151372683 1.74 ENST00000458566.5
ENST00000447402.7
ENST00000426705.6
ENST00000368868.10
selenium binding protein 1
chr15_+_70936487 1.55 ENST00000558456.5
ENST00000560158.6
ENST00000558808.5
ENST00000559806.5
ENST00000559069.1
leucine rich repeat containing 49
chrX_+_41689006 1.53 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
G protein-coupled receptor 34
chr16_-_21303036 1.50 ENST00000219599.8
ENST00000576703.5
crystallin mu
chr5_-_160852200 1.44 ENST00000327245.10
ATPase phospholipid transporting 10B (putative)
chr12_+_48904105 1.38 ENST00000266984.9
coiled-coil domain containing 65
chr5_+_141223332 1.20 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
protocadherin beta 14
novel protein
chr4_-_99435396 1.17 ENST00000209665.8
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr8_+_66126896 1.15 ENST00000353317.9
tripartite motif containing 55
chr9_-_123184233 1.14 ENST00000447404.6
spermatid perinuclear RNA binding protein
chr1_+_61081728 1.11 ENST00000371189.8
nuclear factor I A
chr4_-_99435336 1.11 ENST00000437033.7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr2_-_46542555 1.08 ENST00000522587.6
ATPase H+ transporting V1 subunit E2
chr4_-_99435134 1.04 ENST00000476959.5
ENST00000482593.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr12_-_25648544 1.02 ENST00000540106.5
ENST00000445693.5
ENST00000545543.1
lamin tail domain containing 1
chr3_+_98353854 1.02 ENST00000354924.2
olfactory receptor family 5 subfamily K member 4
chr12_-_121669646 1.02 ENST00000355329.7
MORN repeat containing 3
chr5_+_36608146 0.94 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr7_-_100428657 0.94 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
zinc finger CW-type and PWWP domain containing 1
chr11_-_119196769 0.93 ENST00000415318.2
coiled-coil domain containing 153
chr9_+_105662457 0.90 ENST00000334077.6
TAL bHLH transcription factor 2
chr3_-_58627596 0.89 ENST00000474531.5
ENST00000465970.1
family with sequence similarity 107 member A
chr5_-_42811884 0.88 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr5_+_141121793 0.86 ENST00000194152.4
protocadherin beta 4
chr7_+_123601815 0.80 ENST00000451215.6
ankyrin repeat and SOCS box containing 15
chr8_-_144605699 0.79 ENST00000377307.6
ENST00000276826.5
Rho GTPase activating protein 39
chr3_+_189789672 0.76 ENST00000434928.5
tumor protein p63
chrX_-_112840815 0.75 ENST00000304758.5
ENST00000371959.9
angiomotin
chr6_-_76072654 0.74 ENST00000369950.8
ENST00000611179.4
ENST00000369963.5
interphotoreceptor matrix proteoglycan 1
chr10_-_114684612 0.74 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr20_-_7940444 0.71 ENST00000378789.4
hydroxyacid oxidase 1
chr12_-_14961610 0.71 ENST00000542276.1
Rho GDP dissociation inhibitor beta
chr5_+_96876480 0.69 ENST00000437043.8
ENST00000379904.8
endoplasmic reticulum aminopeptidase 2
chr7_+_120273129 0.65 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2
chr1_-_179143044 0.64 ENST00000504405.5
ENST00000512653.5
ENST00000344730.7
ABL proto-oncogene 2, non-receptor tyrosine kinase
chr7_+_116953379 0.62 ENST00000393449.5
suppression of tumorigenicity 7
chr1_+_244969869 0.62 ENST00000366523.5
EF-hand calcium binding domain 2
chr10_+_84173793 0.61 ENST00000372126.4
chromosome 10 open reading frame 99
chr3_-_149221811 0.60 ENST00000455472.3
ENST00000264613.11
ceruloplasmin
chr6_+_127577168 0.60 ENST00000329722.8
chromosome 6 open reading frame 58
chr1_+_167329044 0.59 ENST00000367862.9
POU class 2 homeobox 1
chr16_+_56191476 0.58 ENST00000262493.12
G protein subunit alpha o1
chr17_-_40822604 0.57 ENST00000269576.6
ENST00000635956.2
keratin 10
chr7_-_130441136 0.57 ENST00000675596.1
ENST00000676312.1
centrosomal protein 41
chr17_+_68259164 0.54 ENST00000448504.6
arylsulfatase G
chr11_+_17295322 0.53 ENST00000458064.6
ENST00000622082.4
nucleobindin 2
chr3_-_62373538 0.53 ENST00000283268.8
FEZ family zinc finger 2
chr5_+_126423363 0.53 ENST00000285689.8
GRAM domain containing 2B
chr3_-_52897541 0.52 ENST00000355083.11
ENST00000504329.1
STIM activating enhancer
STIMATE-MUSTN1 readthrough
chr17_-_69244846 0.52 ENST00000269081.8
ATP binding cassette subfamily A member 10
chr4_-_109801978 0.51 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
complement factor I
novel protein
chr1_+_244352627 0.50 ENST00000366537.5
ENST00000308105.5
chromosome 1 open reading frame 100
chr5_+_126423122 0.49 ENST00000515200.5
GRAM domain containing 2B
chr12_-_91179355 0.48 ENST00000550563.5
ENST00000546370.5
decorin
chr4_-_144019287 0.46 ENST00000638448.1
ENST00000513128.5
ENST00000506516.6
ENST00000429670.3
ENST00000502664.6
glycophorin B (MNS blood group)
chr1_+_19596960 0.46 ENST00000617872.4
ENST00000322753.7
ENST00000602662.1
mitochondrial contact site and cristae organizing system subunit 10
NBL1, DAN family BMP antagonist
chr10_-_92243246 0.45 ENST00000412050.8
ENST00000614585.4
cytoplasmic polyadenylation element binding protein 3
chr7_+_134127299 0.45 ENST00000645682.1
ENST00000285928.2
leucine rich repeats and guanylate kinase domain containing
chr6_-_24877262 0.45 ENST00000378023.8
ENST00000540914.5
RHO family interacting cell polarization regulator 2
chr1_-_1361777 0.45 ENST00000477278.3
matrix remodeling associated 8
chr20_+_45361936 0.44 ENST00000372727.5
ENST00000414310.5
SYS1 golgi trafficking protein
chr5_+_126423176 0.44 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr12_-_9607903 0.43 ENST00000229402.4
killer cell lectin like receptor B1
chr7_+_100428782 0.43 ENST00000414441.5
methylphosphate capping enzyme
chr1_-_216805367 0.43 ENST00000360012.7
estrogen related receptor gamma
chr8_+_60678705 0.43 ENST00000423902.7
chromodomain helicase DNA binding protein 7
chr7_-_105691637 0.42 ENST00000472195.1
ataxin 7 like 1
chr1_+_27773189 0.42 ENST00000373943.9
ENST00000440806.2
syntaxin 12
chr9_-_15472732 0.42 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chrX_-_32155462 0.41 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chrX_-_81201886 0.40 ENST00000451455.1
ENST00000358130.7
ENST00000436386.5
high mobility group nucleosome binding domain 5
chr13_+_27792479 0.38 ENST00000302945.3
GS homeobox 1
chr1_-_48400826 0.38 ENST00000371841.1
spermatogenesis associated 6
chr5_-_161546970 0.37 ENST00000675303.1
gamma-aminobutyric acid type A receptor subunit beta2
chr12_-_9733292 0.37 ENST00000621400.4
ENST00000327839.3
C-type lectin like 1
chr11_-_57237183 0.36 ENST00000606794.1
apelin receptor
chr5_-_111976925 0.35 ENST00000395634.7
neuronal regeneration related protein
chr17_-_42388467 0.35 ENST00000678792.1
ENST00000679166.1
ENST00000677442.1
ENST00000677723.1
ENST00000678905.1
ENST00000677479.1
ENST00000678043.1
ENST00000677152.1
ENST00000677603.1
ENST00000588969.5
ENST00000678535.1
ENST00000679185.1
ENST00000677030.1
ENST00000679014.1
ENST00000678044.1
ENST00000678827.1
signal transducer and activator of transcription 3
chr7_+_123601836 0.35 ENST00000434204.5
ankyrin repeat and SOCS box containing 15
chr11_-_35420017 0.35 ENST00000643000.1
ENST00000646099.1
ENST00000647372.1
ENST00000642578.1
solute carrier family 1 member 2
chr2_-_158380960 0.35 ENST00000409187.5
coiled-coil domain containing 148
chr14_-_25010604 0.34 ENST00000550887.5
syntaxin binding protein 6
chr11_-_59810750 0.34 ENST00000300151.5
mitochondrial ribosomal protein L16
chr22_+_30080460 0.34 ENST00000336726.11
HORMA domain containing 2
chr1_-_169734064 0.34 ENST00000333360.12
selectin E
chr17_-_42388360 0.33 ENST00000678960.1
ENST00000404395.3
ENST00000389272.7
ENST00000677421.1
ENST00000585517.5
ENST00000264657.10
ENST00000678048.1
ENST00000678674.1
ENST00000678913.1
ENST00000678572.1
ENST00000678906.1
signal transducer and activator of transcription 3
chr5_+_141968886 0.33 ENST00000347642.7
ring finger protein 14
chr17_-_52158678 0.33 ENST00000451037.7
carbonic anhydrase 10
chr3_+_148791058 0.33 ENST00000491148.5
carboxypeptidase B1
chr12_+_51590873 0.32 ENST00000667214.1
ENST00000662684.1
ENST00000638820.1
sodium voltage-gated channel alpha subunit 8
chr17_+_17782108 0.31 ENST00000395774.1
retinoic acid induced 1
chr19_-_10587219 0.31 ENST00000591240.5
ENST00000589684.5
ENST00000591676.1
ENST00000250244.11
ENST00000590923.5
adaptor related protein complex 1 subunit mu 2
chr13_-_70108441 0.31 ENST00000377844.9
ENST00000545028.2
kelch like family member 1
chr6_-_154430495 0.31 ENST00000424998.3
CNKSR family member 3
chr6_+_27824084 0.30 ENST00000355057.3
H4 clustered histone 11
chr11_+_120236635 0.30 ENST00000260264.8
POU class 2 homeobox 3
chr17_+_3475959 0.30 ENST00000263080.3
aspartoacylase
chr10_-_126670686 0.30 ENST00000488181.3
chromosome 10 open reading frame 90
chr6_-_46491956 0.30 ENST00000306764.11
regulator of calcineurin 2
chr9_-_137302264 0.29 ENST00000356628.4
NOTCH regulated ankyrin repeat protein
chr14_+_100019375 0.29 ENST00000544450.6
Enah/Vasp-like
chr7_-_32490361 0.29 ENST00000410044.5
ENST00000450169.7
ENST00000409987.5
ENST00000409782.5
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr12_-_51324652 0.29 ENST00000544402.5
bridging integrator 2
chr17_-_8119047 0.28 ENST00000318227.4
arachidonate lipoxygenase 3
chr3_-_149657996 0.28 ENST00000360632.8
ENST00000467467.5
ENST00000460517.1
WW domain containing transcription regulator 1
chr12_+_49346911 0.27 ENST00000395069.3
DnaJ heat shock protein family (Hsp40) member C22
chrX_+_79144664 0.27 ENST00000645147.2
G protein-coupled receptor 174
chr7_-_50561048 0.26 ENST00000380984.4
ENST00000357936.9
ENST00000426377.5
ENST00000615193.4
ENST00000617822.4
ENST00000622873.4
dopa decarboxylase
chr3_-_62374293 0.26 ENST00000486811.5
FEZ family zinc finger 2
chr8_-_85341705 0.26 ENST00000517618.5
carbonic anhydrase 1
chr2_-_60553409 0.26 ENST00000358510.6
ENST00000643004.1
BAF chromatin remodeling complex subunit BCL11A
chr11_+_124954108 0.26 ENST00000529051.5
coiled-coil domain containing 15
chr6_+_131573219 0.26 ENST00000356962.2
ENST00000368087.8
ENST00000673427.1
ENST00000640973.1
arginase 1
chr12_+_25052634 0.26 ENST00000548766.5
inositol 1,4,5-triphosphate receptor associated 2
chr1_-_46551647 0.26 ENST00000481882.7
kinocilin
chr12_+_25052732 0.26 ENST00000547044.5
inositol 1,4,5-triphosphate receptor associated 2
chr5_-_36151853 0.26 ENST00000296603.5
LMBR1 domain containing 2
chr8_-_64798725 0.25 ENST00000310193.4
cytochrome P450 family 7 subfamily B member 1
chr16_+_83971451 0.25 ENST00000565691.5
N-terminal EF-hand calcium binding protein 2
chr16_+_67893244 0.25 ENST00000291041.6
ENST00000570631.5
protein serine kinase H1
chr1_-_77219399 0.25 ENST00000359130.1
ENST00000370812.8
ENST00000445065.5
phosphatidylinositol glycan anchor biosynthesis class K
chr4_+_174918400 0.25 ENST00000404450.8
ENST00000514159.1
ADAM metallopeptidase domain 29
chr7_-_38909174 0.25 ENST00000395969.6
ENST00000310301.9
ENST00000414632.5
VPS41 subunit of HOPS complex
chr12_-_39340963 0.25 ENST00000552961.5
kinesin family member 21A
chrX_+_10158448 0.24 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr11_-_35419899 0.24 ENST00000646847.1
ENST00000449068.2
ENST00000643401.1
ENST00000645966.1
ENST00000647104.1
solute carrier family 1 member 2
chr5_+_146203544 0.24 ENST00000506502.2
novel readthrough transcript
chr1_-_6554501 0.23 ENST00000377705.6
nucleolar protein 9
chr16_-_31442763 0.23 ENST00000315678.10
zinc finger protein 843
chr11_-_40293102 0.22 ENST00000527150.5
leucine rich repeat containing 4C
chr5_+_140125935 0.22 ENST00000333305.5
IgA inducing protein
chr5_+_42756811 0.22 ENST00000388827.4
ENST00000361970.10
coiled-coil domain containing 152
chrX_+_106611930 0.22 ENST00000372544.6
ENST00000372548.9
RPA1 related single stranded DNA binding protein, X-linked
chr20_+_59604527 0.22 ENST00000371015.6
phosphatase and actin regulator 3
chr10_-_27243019 0.22 ENST00000679293.1
acyl-CoA binding domain containing 5
chr5_+_43121596 0.22 ENST00000505606.6
ENST00000509634.5
ENST00000509341.5
zinc finger protein 131
chr3_+_12484421 0.21 ENST00000681713.1
ENST00000679699.1
ENST00000446004.6
ENST00000679756.1
ENST00000681343.1
ENST00000415684.6
ENST00000412698.3
ENST00000454502.6
ENST00000284995.11
ENST00000402228.7
ENST00000680275.1
ENST00000681676.1
ENST00000681042.1
ENST00000679492.1
ENST00000680857.1
tRNA splicing endonuclease subunit 2
chr5_-_161546671 0.21 ENST00000517547.5
gamma-aminobutyric acid type A receptor subunit beta2
chr20_+_31968141 0.21 ENST00000562532.3
XK related 7
chr1_-_111488795 0.21 ENST00000472933.2
transmembrane and immunoglobulin domain containing 3
chr1_+_111473792 0.21 ENST00000343534.9
chromosome 1 open reading frame 162
chr21_-_41926680 0.21 ENST00000329623.11
C2 calcium dependent domain containing 2
chr5_+_141382702 0.21 ENST00000617050.1
ENST00000518325.2
protocadherin gamma subfamily A, 7
chr15_+_66505289 0.20 ENST00000565627.5
ENST00000564179.5
ENST00000307897.10
zwilch kinetochore protein
chr12_+_25052512 0.20 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
inositol 1,4,5-triphosphate receptor associated 2
chr5_+_43121504 0.20 ENST00000509156.5
ENST00000508259.5
ENST00000306938.8
zinc finger protein 131
chr1_+_100538131 0.20 ENST00000315033.5
G protein-coupled receptor 88
chr15_+_66504959 0.20 ENST00000535141.6
ENST00000613446.4
ENST00000446801.6
zwilch kinetochore protein
chrX_+_131058340 0.19 ENST00000276211.10
ENST00000370922.5
Rho GTPase activating protein 36
chr16_+_31117656 0.19 ENST00000219797.9
ENST00000448516.6
lysine acetyltransferase 8
chr2_-_219399981 0.19 ENST00000519905.1
ENST00000523282.5
ENST00000434339.5
ENST00000457935.5
aspartyl aminopeptidase
chr3_+_12484540 0.19 ENST00000680943.1
ENST00000680421.1
ENST00000679367.1
ENST00000679876.1
ENST00000444864.6
ENST00000680986.1
tRNA splicing endonuclease subunit 2
chr12_+_57610150 0.18 ENST00000333972.11
Rho guanine nucleotide exchange factor 25
chr5_-_161546708 0.18 ENST00000393959.6
gamma-aminobutyric acid type A receptor subunit beta2
chr1_-_247758680 0.18 ENST00000408896.4
olfactory receptor family 1 subfamily C member 1
chr11_-_4608226 0.18 ENST00000300747.10
ENST00000526337.5
tripartite motif containing 68
chrM_+_5824 0.18 ENST00000361624.2
mitochondrially encoded cytochrome c oxidase I
chr11_+_3808532 0.18 ENST00000278243.9
ENST00000463452.6
ENST00000479072.5
ENST00000496834.6
ENST00000469307.4
post-GPI attachment to proteins 2
chr6_-_47309898 0.18 ENST00000296861.2
TNF receptor superfamily member 21
chr17_-_63911236 0.17 ENST00000438387.6
ENST00000346606.10
ENST00000309894.6
ENST00000561003.5
ENST00000450719.3
ENST00000259003.14
chorionic somatomammotropin hormone like 1
chr1_+_111473972 0.17 ENST00000369718.4
chromosome 1 open reading frame 162
chr12_-_101830926 0.17 ENST00000299314.12
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
chr15_-_76012390 0.17 ENST00000394907.8
neuregulin 4
chr16_-_3577375 0.17 ENST00000359128.10
NLR family CARD domain containing 3
chr12_-_7695752 0.16 ENST00000329913.4
growth differentiation factor 3
chr1_+_167220870 0.16 ENST00000367866.7
ENST00000429375.6
ENST00000541643.7
POU class 2 homeobox 1
chr9_+_35042213 0.16 ENST00000378745.3
ENST00000312292.6
chromosome 9 open reading frame 131
chr6_+_29396555 0.16 ENST00000623183.1
olfactory receptor family 12 subfamily D member 2
chr11_-_102625332 0.16 ENST00000260228.3
matrix metallopeptidase 20
chr12_-_91179472 0.16 ENST00000550099.5
ENST00000546391.5
decorin
chr2_-_174846405 0.16 ENST00000409597.5
ENST00000413882.6
chimerin 1
chr3_-_15798184 0.15 ENST00000624145.3
ankyrin repeat domain 28
chr13_+_52012375 0.15 ENST00000649708.2
ENST00000523764.1
ENST00000649340.2
ENST00000679544.1
ENST00000681053.1
ENST00000521508.2
ENST00000616513.1
ALG11 alpha-1,2-mannosyltransferase
chr5_+_140794832 0.15 ENST00000378132.2
ENST00000526136.2
ENST00000520672.2
protocadherin alpha 2
chr7_-_139777986 0.15 ENST00000406875.8
homeodomain interacting protein kinase 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.1 GO:2000768 positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.8 3.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.6 4.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.4 2.9 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.3 4.7 GO:0006600 creatine metabolic process(GO:0006600)
0.2 0.7 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.2 2.0 GO:0006069 ethanol oxidation(GO:0006069)
0.2 0.5 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.4 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 3.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.7 GO:0071461 cellular response to redox state(GO:0071461)
0.1 1.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.5 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 2.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.3 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 1.7 GO:0019321 pentose metabolic process(GO:0019321)
0.1 0.4 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 0.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.9 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 2.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.3 GO:1903860 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 6.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 0.3 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.3 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.1 4.8 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.2 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.1 0.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.7 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.4 GO:0040031 snRNA modification(GO:0040031)
0.0 0.7 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.9 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.6 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.8 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 1.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.1 GO:0072189 ureter development(GO:0072189)
0.0 0.6 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.2 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 1.3 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988)
0.0 6.7 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.3 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0090264 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.0 1.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.8 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.0 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.4 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:1901253 mesodermal cell fate determination(GO:0007500) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.3 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.4 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.4 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.8 GO:0010863 positive regulation of phospholipase C activity(GO:0010863)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.6 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.0 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.0 0.4 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.6 GO:0050832 defense response to fungus(GO:0050832)
0.0 2.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 2.1 GO:0036157 outer dynein arm(GO:0036157)
0.1 2.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.4 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.4 GO:1990423 RZZ complex(GO:1990423)
0.1 1.1 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.4 GO:0002177 manchette(GO:0002177)
0.1 0.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0060171 stereocilium membrane(GO:0060171)
0.0 4.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 4.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 3.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0004556 alpha-amylase activity(GO:0004556)
1.0 5.8 GO:0004522 ribonuclease A activity(GO:0004522)
0.8 3.3 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.7 0.7 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.6 2.9 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.6 1.7 GO:0019150 D-ribulokinase activity(GO:0019150)
0.4 2.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.4 1.5 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.3 2.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 2.5 GO:0008430 selenium binding(GO:0008430)
0.2 2.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 3.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 4.7 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 1.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.1 0.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.8 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 0.7 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 5.8 GO:0042805 actinin binding(GO:0042805)
0.1 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 1.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.5 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.4 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.4 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 2.8 GO:0003774 motor activity(GO:0003774)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0046790 virion binding(GO:0046790)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 4.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 24.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.4 5.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 4.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 5.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis