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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for POU5F1_POU2F3

Z-value: 0.83

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Transcription factors associated with POU5F1_POU2F3

Gene Symbol Gene ID Gene Info
ENSG00000204531.20 POU5F1
ENSG00000137709.10 POU2F3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU5F1hg38_v1_chr6_-_31170620_311706980.451.4e-02Click!
POU2F3hg38_v1_chr11_+_120236635_120236642,
hg38_v1_chr11_+_120240135_120240199
-0.048.2e-01Click!

Activity profile of POU5F1_POU2F3 motif

Sorted Z-values of POU5F1_POU2F3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_+_79279403 1.77 ENST00000281127.11
neurexin 3
chr2_+_10721649 1.47 ENST00000381661.3
ATPase H+ transporting V1 subunit C2
chr2_+_10721623 1.46 ENST00000272238.9
ATPase H+ transporting V1 subunit C2
chr2_-_89245596 1.37 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr2_+_89936859 1.35 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr8_+_84705920 1.25 ENST00000523850.5
ENST00000521376.1
RALY RNA binding protein like
chr12_-_91180365 1.17 ENST00000547937.5
decorin
chr19_+_52369911 1.09 ENST00000424032.6
ENST00000422689.3
ENST00000600321.5
ENST00000344085.9
ENST00000597976.5
zinc finger protein 880
chr8_+_39902275 1.07 ENST00000518804.5
ENST00000519154.5
ENST00000522495.5
ENST00000522840.1
indoleamine 2,3-dioxygenase 1
chr6_+_26124161 0.91 ENST00000377791.4
ENST00000602637.1
H2A clustered histone 6
chr2_+_89947508 0.90 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr21_-_10649835 0.90 ENST00000622028.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr1_-_149886652 0.90 ENST00000369155.3
H2B clustered histone 21
chr4_+_74933095 0.85 ENST00000513238.5
prostate androgen-regulated mucin-like protein 1
chr4_+_74933108 0.84 ENST00000307428.7
prostate androgen-regulated mucin-like protein 1
chr11_+_111245725 0.84 ENST00000280325.7
chromosome 11 open reading frame 53
chr6_+_25726767 0.83 ENST00000274764.5
H2B clustered histone 1
chr19_-_17405554 0.81 ENST00000252593.7
bone marrow stromal cell antigen 2
chr19_-_43619591 0.80 ENST00000598676.1
ENST00000300811.8
zinc finger protein 428
chr14_+_79279339 0.78 ENST00000557594.5
neurexin 3
chr7_-_100586119 0.77 ENST00000310300.11
leucine rich repeats and calponin homology domain containing 4
chr14_+_79279681 0.76 ENST00000679122.1
neurexin 3
chr12_-_91179355 0.75 ENST00000550563.5
ENST00000546370.5
decorin
chr11_+_111255982 0.71 ENST00000637637.1
chromosome 11 open reading frame 53
chrX_-_24647091 0.70 ENST00000356768.8
phosphate cytidylyltransferase 1, choline, beta
chr3_-_132035004 0.68 ENST00000429747.6
copine 4
chr6_-_35688907 0.68 ENST00000539068.5
ENST00000357266.9
FKBP prolyl isomerase 5
chr17_+_14301069 0.67 ENST00000360954.3
heparan sulfate-glucosamine 3-sulfotransferase 3B1
chr5_+_96876480 0.67 ENST00000437043.8
ENST00000379904.8
endoplasmic reticulum aminopeptidase 2
chr22_-_18936142 0.66 ENST00000438924.5
ENST00000457083.1
ENST00000357068.11
ENST00000420436.5
ENST00000334029.6
ENST00000610940.4
proline dehydrogenase 1
chr2_+_89959979 0.64 ENST00000453166.2
immunoglobulin kappa variable 2D-28
chr1_-_153057504 0.63 ENST00000392653.3
small proline rich protein 2A
chr5_-_178590367 0.63 ENST00000390654.8
collagen type XXIII alpha 1 chain
chr17_-_75779758 0.63 ENST00000592643.5
ENST00000591890.5
ENST00000587171.1
ENST00000254810.8
ENST00000589599.5
H3.3 histone B
chr11_+_27055215 0.62 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr6_-_27146841 0.62 ENST00000356950.2
H2B clustered histone 12
chr6_+_26183750 0.59 ENST00000614097.3
H2B clustered histone 6
chr22_+_22594528 0.59 ENST00000390303.3
immunoglobulin lambda variable 3-32 (non-functional)
chr8_+_7894674 0.58 ENST00000302247.3
defensin beta 4A
chr22_+_22704265 0.58 ENST00000390307.2
immunoglobulin lambda variable 3-22
chr1_-_228457855 0.56 ENST00000366695.3
H2A.W histone
chrX_+_81202066 0.55 ENST00000373212.6
SH3 domain binding glutamate rich protein like
chr16_+_19410723 0.55 ENST00000381414.8
ENST00000396229.6
transmembrane channel like 5
chr12_-_91182652 0.54 ENST00000552145.5
ENST00000546745.5
decorin
chr2_+_89851723 0.54 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr5_+_96875978 0.53 ENST00000510373.5
endoplasmic reticulum aminopeptidase 2
chr2_+_90038848 0.53 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr6_+_26251607 0.53 ENST00000619466.2
H2B clustered histone 9
chr2_-_89222461 0.52 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr6_-_26043704 0.52 ENST00000615966.2
H2B clustered histone 3
chr1_-_149812359 0.52 ENST00000369167.2
ENST00000545683.1
H2B clustered histone 18
chr8_-_7416863 0.51 ENST00000318157.3
defensin beta 4B
chr22_+_22818994 0.51 ENST00000390316.2
immunoglobulin lambda variable 3-9
chr14_+_103107516 0.49 ENST00000560304.1
exocyst complex component 3 like 4
chr4_+_48483324 0.48 ENST00000273861.5
solute carrier family 10 member 4
chr3_+_319683 0.48 ENST00000620033.4
cell adhesion molecule L1 like
chr12_-_122716790 0.46 ENST00000528880.3
hydroxycarboxylic acid receptor 3
chr2_-_89143133 0.46 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr12_-_122703346 0.46 ENST00000328880.6
hydroxycarboxylic acid receptor 2
chr16_+_33009175 0.46 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr11_-_27472698 0.45 ENST00000389858.4
ENST00000379214.9
leucine rich repeat containing G protein-coupled receptor 4
chr5_-_111756245 0.45 ENST00000447165.6
neuronal regeneration related protein
chr20_+_59676661 0.45 ENST00000355648.8
phosphatase and actin regulator 3
chr1_+_117001744 0.45 ENST00000256652.8
ENST00000682167.1
ENST00000369470.1
CD101 molecule
chr11_-_133845495 0.45 ENST00000299140.8
ENST00000532889.1
spermatogenesis associated 19
chr17_+_45135640 0.44 ENST00000586346.5
ENST00000321854.13
ENST00000398322.7
ENST00000592162.5
ENST00000376955.8
acyl-CoA binding domain containing 4
chr14_-_106154113 0.44 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr16_+_19410480 0.44 ENST00000541464.5
transmembrane channel like 5
chr9_+_133459965 0.44 ENST00000540581.5
ENST00000542192.5
ENST00000291722.11
ENST00000316948.9
calcium channel flower domain containing 1
chr12_-_91182784 0.43 ENST00000547568.6
ENST00000052754.10
ENST00000552962.5
decorin
chr9_-_21141832 0.43 ENST00000380229.4
interferon omega 1
chr11_+_73308237 0.43 ENST00000263674.4
Rho guanine nucleotide exchange factor 17
chr5_-_27038576 0.43 ENST00000511822.1
ENST00000231021.9
cadherin 9
chr11_-_34357994 0.42 ENST00000435224.3
ankyrin repeat and BTB domain containing 2
chrX_-_64205680 0.42 ENST00000374869.8
APC membrane recruitment protein 1
chr19_-_1132208 0.42 ENST00000438103.6
strawberry notch homolog 2
chr1_-_154859841 0.42 ENST00000361147.8
potassium calcium-activated channel subfamily N member 3
chr1_-_153094521 0.42 ENST00000368750.8
small proline rich protein 2E
chr19_+_7669080 0.41 ENST00000629642.1
resistin
chr15_-_90935130 0.41 ENST00000646620.1
HD domain containing 3
chr14_-_106622837 0.41 ENST00000390628.3
immunoglobulin heavy variable 1-58
chr14_-_106117159 0.40 ENST00000390601.3
immunoglobulin heavy variable 3-11
chr21_+_42403856 0.40 ENST00000291535.11
ubiquitin associated and SH3 domain containing A
chr6_-_81752671 0.40 ENST00000320172.11
ENST00000369754.7
ENST00000369756.3
terminal nucleotidyltransferase 5A
chr12_-_10909562 0.40 ENST00000390677.2
taste 2 receptor member 13
chr22_+_22871478 0.39 ENST00000390318.2
immunoglobulin lambda variable 4-3
chr21_-_41926680 0.39 ENST00000329623.11
C2 calcium dependent domain containing 2
chr6_-_29559724 0.39 ENST00000377050.5
ubiquitin D
chr4_+_41612702 0.39 ENST00000509277.5
LIM and calponin homology domains 1
chr6_+_27815010 0.38 ENST00000621112.2
H2B clustered histone 14
chr16_-_11636357 0.38 ENST00000576334.1
ENST00000574848.5
lipopolysaccharide induced TNF factor
chr4_+_41612892 0.38 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIM and calponin homology domains 1
chr6_-_52803807 0.37 ENST00000334575.6
glutathione S-transferase alpha 1
chr14_-_106389858 0.37 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr17_-_15598618 0.36 ENST00000583965.5
CMT1A duplicated region transcript 1
chr1_+_228458095 0.36 ENST00000620438.1
H2B.U histone 1
chr12_+_131828386 0.36 ENST00000360564.5
matrix metallopeptidase 17
chr7_+_80646305 0.36 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr2_-_157325808 0.35 ENST00000410096.6
ENST00000420719.6
ENST00000409216.5
ENST00000419116.2
ermin
chr15_-_45114149 0.35 ENST00000603300.1
ENST00000389039.11
dual oxidase 2
chr14_-_105987068 0.35 ENST00000390594.3
immunoglobulin heavy variable 1-2
chr16_+_82626955 0.35 ENST00000268613.14
ENST00000567109.6
ENST00000565636.5
ENST00000431540.7
ENST00000428848.7
cadherin 13
chr22_+_22162155 0.35 ENST00000390284.2
immunoglobulin lambda variable 4-60
chr12_-_81758641 0.35 ENST00000552948.5
ENST00000548586.5
PTPRF interacting protein alpha 2
chr14_-_94476240 0.34 ENST00000424550.6
ENST00000337425.10
ENST00000674164.1
ENST00000546329.2
serpin family A member 9
chr1_+_59310071 0.34 ENST00000371212.5
FGGY carbohydrate kinase domain containing
chr14_-_106360320 0.33 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr3_-_71305986 0.33 ENST00000647614.1
forkhead box P1
chr6_-_32589833 0.33 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr1_+_207325629 0.32 ENST00000618707.2
CD55 molecule (Cromer blood group)
chr6_-_137219340 0.32 ENST00000367739.9
ENST00000458076.5
ENST00000414770.5
interferon gamma receptor 1
chr14_-_106715166 0.32 ENST00000390633.2
immunoglobulin heavy variable 1-69
chrX_-_51682831 0.32 ENST00000634648.1
centromere protein V like 2
chr11_-_31810991 0.32 ENST00000640684.1
paired box 6
chr21_+_42403874 0.32 ENST00000319294.11
ENST00000398367.1
ubiquitin associated and SH3 domain containing A
chrX_+_57286680 0.32 ENST00000374900.5
fatty acid amide hydrolase 2
chr2_+_90021567 0.31 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr12_+_6943811 0.31 ENST00000544681.1
ENST00000537087.5
chromosome 12 open reading frame 57
chr7_+_80646436 0.31 ENST00000419819.2
CD36 molecule
chr12_-_66678934 0.31 ENST00000545666.5
ENST00000398016.7
ENST00000359742.9
ENST00000538211.5
glutamate receptor interacting protein 1
chr13_-_99307387 0.31 ENST00000376414.5
G protein-coupled receptor 183
chr14_-_106538331 0.31 ENST00000390624.3
immunoglobulin heavy variable 3-48
chrX_+_73447042 0.31 ENST00000373514.3
caudal type homeobox 4
chr12_+_20810698 0.31 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr1_-_177164673 0.31 ENST00000424564.2
ENST00000361833.7
astrotactin 1
chr19_-_1021114 0.31 ENST00000333175.9
ENST00000356663.8
transmembrane protein 259
chr12_-_91179472 0.30 ENST00000550099.5
ENST00000546391.5
decorin
chr4_+_75556048 0.30 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
odontogenesis associated phosphoprotein
chr1_+_67685170 0.30 ENST00000370985.4
ENST00000370986.9
ENST00000650283.1
ENST00000648742.1
growth arrest and DNA damage inducible alpha
chr1_-_153375591 0.30 ENST00000368737.5
S100 calcium binding protein A12
chr2_+_90069662 0.30 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr2_-_88947820 0.30 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr14_-_106627685 0.30 ENST00000390629.3
immunoglobulin heavy variable 4-59
chr3_-_79767987 0.30 ENST00000464233.6
roundabout guidance receptor 1
chr4_+_69931066 0.30 ENST00000246891.9
casein alpha s1
chr2_+_233691607 0.30 ENST00000373424.5
ENST00000441351.1
UDP glucuronosyltransferase family 1 member A6
chr4_+_87799546 0.30 ENST00000226284.7
integrin binding sialoprotein
chr22_-_27801712 0.29 ENST00000302326.5
MN1 proto-oncogene, transcriptional regulator
chr6_+_27893411 0.29 ENST00000616182.2
H2B clustered histone 17
chr12_+_6944065 0.29 ENST00000540506.2
chromosome 12 open reading frame 57
chr10_+_100462969 0.29 ENST00000343737.6
Wnt family member 8B
chr3_-_114199407 0.29 ENST00000460779.5
dopamine receptor D3
chr7_-_3043838 0.29 ENST00000356408.3
ENST00000396946.9
caspase recruitment domain family member 11
chr12_+_6944009 0.29 ENST00000229281.6
chromosome 12 open reading frame 57
chr22_+_22195753 0.29 ENST00000390285.4
immunoglobulin lambda variable 6-57
chr2_-_89160329 0.28 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr14_-_106762576 0.28 ENST00000624687.1
immunoglobulin heavy variable 1-69D
chr7_-_151248668 0.28 ENST00000262188.13
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr9_+_92964272 0.28 ENST00000468206.6
FYVE, RhoGEF and PH domain containing 3
chr14_-_106557465 0.28 ENST00000390625.3
immunoglobulin heavy variable 3-49
chr6_+_116369837 0.28 ENST00000645988.1
dermatan sulfate epimerase
chr15_-_19965101 0.28 ENST00000338912.5
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr22_+_22030934 0.28 ENST00000390282.2
immunoglobulin lambda variable 4-69
chr5_-_67196791 0.28 ENST00000256447.5
CD180 molecule
chr11_+_102317492 0.28 ENST00000673846.1
baculoviral IAP repeat containing 3
chr1_-_75611109 0.28 ENST00000370859.7
solute carrier family 44 member 5
chr15_+_67065586 0.28 ENST00000327367.9
SMAD family member 3
chr9_-_124771304 0.28 ENST00000416460.6
ENST00000487099.7
nuclear receptor subfamily 6 group A member 1
chr1_-_39691450 0.27 ENST00000612703.3
ENST00000617690.2
hippocalcin like 4
chr14_-_106803221 0.27 ENST00000390636.2
immunoglobulin heavy variable 3-73
chr11_+_121102666 0.27 ENST00000264037.2
tectorin alpha
chr4_-_47837949 0.27 ENST00000505909.5
ENST00000273857.9
ENST00000502252.5
corin, serine peptidase
chr19_-_54463762 0.27 ENST00000611161.2
leukocyte receptor cluster member 9
chr14_-_20802836 0.27 ENST00000397967.5
ENST00000555698.5
ENST00000397970.4
ENST00000340900.3
ribonuclease A family member 1, pancreatic
chr16_-_74774812 0.27 ENST00000219368.8
fatty acid 2-hydroxylase
chr18_+_65750628 0.27 ENST00000536984.6
cadherin 7
chr19_+_55600277 0.27 ENST00000301073.4
zinc finger protein 524
chr2_-_29921580 0.27 ENST00000389048.8
ALK receptor tyrosine kinase
chr16_-_33845229 0.27 ENST00000569103.2
immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr1_-_151006795 0.27 ENST00000312210.9
ENST00000683666.1
MINDY lysine 48 deubiquitinase 1
chr22_+_32354885 0.26 ENST00000397468.5
ret finger protein like 3
chr1_-_39691393 0.26 ENST00000372844.8
hippocalcin like 4
chr3_-_193554952 0.26 ENST00000392443.7
ATPase 13A4
chr9_+_89605004 0.26 ENST00000252506.11
ENST00000375769.1
growth arrest and DNA damage inducible gamma
chr11_+_102317542 0.26 ENST00000532808.5
baculoviral IAP repeat containing 3
chr22_+_22409755 0.26 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr19_+_21020675 0.26 ENST00000595401.1
zinc finger protein 430
chr16_-_79599902 0.26 ENST00000569649.1
MAF bZIP transcription factor
chr17_+_40015428 0.26 ENST00000394149.8
ENST00000225474.6
ENST00000331769.6
ENST00000394148.7
ENST00000577675.1
colony stimulating factor 3
chr12_-_10986912 0.26 ENST00000506868.1
taste 2 receptor member 50
chr6_+_24356903 0.26 ENST00000274766.2
kidney associated antigen 1
chr18_-_55422306 0.26 ENST00000566777.5
ENST00000626584.2
transcription factor 4
chr6_+_21593742 0.26 ENST00000244745.4
SRY-box transcription factor 4
chr7_-_77199808 0.26 ENST00000248598.6
fibrinogen like 2
chr17_+_40062956 0.26 ENST00000450525.7
thyroid hormone receptor alpha
chr1_+_149886906 0.26 ENST00000331380.4
H2A clustered histone 20
chr11_+_64305497 0.26 ENST00000406310.6
ENST00000677967.1
ENST00000000442.11
estrogen related receptor alpha
chr11_+_102317450 0.25 ENST00000615299.4
ENST00000527309.2
ENST00000526421.6
ENST00000263464.9
baculoviral IAP repeat containing 3
chr7_+_130293134 0.25 ENST00000445470.6
ENST00000492072.5
ENST00000222482.10
ENST00000473956.5
ENST00000493259.5
ENST00000486598.1
carboxypeptidase A4
chr4_+_72031902 0.25 ENST00000344413.6
ENST00000308744.12
neuropeptide FF receptor 2
chr7_+_129368123 0.25 ENST00000460109.5
ENST00000474594.5
adenosylhomocysteinase like 2
chr8_+_12104389 0.25 ENST00000400085.7
zinc finger protein 705D
chr16_-_75251482 0.25 ENST00000393420.10
ENST00000162330.10
BCAR1 scaffold protein, Cas family member
chrX_-_6228835 0.25 ENST00000381095.8
neuroligin 4 X-linked
chrX_+_7147237 0.25 ENST00000666110.2
steroid sulfatase
chr14_-_106593319 0.25 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr14_-_106025628 0.25 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr9_-_72060590 0.25 ENST00000652156.1
chromosome 9 open reading frame 57
chr2_+_90209873 0.24 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr5_+_140855882 0.24 ENST00000562220.2
ENST00000307360.6
ENST00000506939.6
protocadherin alpha 10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0036269 swimming behavior(GO:0036269)
0.3 0.8 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.2 0.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 3.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.5 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.4 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.4 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.5 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.1 1.1 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 0.9 GO:0021678 third ventricle development(GO:0021678)
0.1 3.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.3 GO:0010768 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.1 0.6 GO:0071105 response to interleukin-11(GO:0071105)
0.1 0.3 GO:0021658 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.1 0.5 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.3 GO:0048850 cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
0.1 1.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.3 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.1 2.9 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 11.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.3 GO:0050925 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.1 0.3 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.6 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.4 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.1 0.3 GO:0000023 maltose metabolic process(GO:0000023)
0.1 0.3 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.3 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.2 GO:0034963 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 0.3 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.1 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.2 GO:0018032 protein amidation(GO:0018032)
0.1 0.3 GO:2000691 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.2 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.1 0.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.1 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.2 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.2 GO:0051463 negative regulation of cortisol secretion(GO:0051463)
0.1 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.4 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.3 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.8 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.2 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.0 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340) regulation of embryonic cell shape(GO:0016476)
0.0 0.4 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.7 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:1990180 tRNA 3'-trailer cleavage, endonucleolytic(GO:0034414) tRNA 3'-trailer cleavage(GO:0042779) mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.8 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.2 GO:0002265 astrocyte activation involved in immune response(GO:0002265)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.7 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0060366 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.0 5.3 GO:0002377 immunoglobulin production(GO:0002377)
0.0 1.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.2 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.1 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.0 0.3 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.2 GO:0097105 brainstem development(GO:0003360) presynaptic membrane assembly(GO:0097105)
0.0 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603) synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.0 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0060003 copper ion export(GO:0060003)
0.0 0.1 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.3 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.0 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.3 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 1.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.2 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.0 GO:0016068 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.0 0.1 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.1 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.5 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.2 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.1 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.1 GO:0009397 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.3 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.5 GO:0035640 exploration behavior(GO:0035640)
0.0 0.2 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.3 GO:0002312 B cell activation involved in immune response(GO:0002312) mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.0 GO:0015888 thiamine transport(GO:0015888)
0.0 0.0 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.0 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 0.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.8 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.1 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.0 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:0015870 acetylcholine transport(GO:0015870)
0.0 0.0 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.0 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.2 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.4 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.0 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.0 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.1 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.0 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.0 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2 3.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 0.5 GO:0071756 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.1 0.4 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.1 3.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0098560 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0071546 pi-body(GO:0071546)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0016011 dystroglycan complex(GO:0016011)
0.0 1.4 GO:0005771 multivesicular body(GO:0005771)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0070449 elongin complex(GO:0070449)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.1 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 1.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.5 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.7 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.3 2.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 0.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 0.6 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.4 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.4 GO:0016794 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity(GO:0008893) diphosphoric monoester hydrolase activity(GO:0016794)
0.1 3.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.3 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.3 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.4 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.1 0.3 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.2 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.8 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.3 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.2 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 14.5 GO:0003823 antigen binding(GO:0003823)
0.1 1.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.2 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.2 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 0.3 GO:0042835 BRE binding(GO:0042835)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.2 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 3.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.4 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.5 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.0 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID IGF1 PATHWAY IGF1 pathway
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.0 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC