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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for POU6F2

Z-value: 0.58

Motif logo

Transcription factors associated with POU6F2

Gene Symbol Gene ID Gene Info
ENSG00000106536.21 POU6F2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU6F2hg38_v1_chr7_+_38977904_389780090.242.0e-01Click!

Activity profile of POU6F2 motif

Sorted Z-values of POU6F2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU6F2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_127646145 1.50 ENST00000486700.2
ENST00000272644.7
G protein-coupled receptor 17
chr2_+_127645864 1.49 ENST00000544369.5
G protein-coupled receptor 17
chr12_-_30735014 1.39 ENST00000433722.6
caprin family member 2
chr6_+_151325665 1.23 ENST00000354675.10
A-kinase anchoring protein 12
chr1_-_182672232 1.11 ENST00000508450.5
regulator of G protein signaling 8
chr19_-_14112641 0.90 ENST00000536649.5
protein kinase cAMP-activated catalytic subunit alpha
chr3_-_33645433 0.89 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr10_+_92593112 0.89 ENST00000260731.5
kinesin family member 11
chr5_-_140346596 0.87 ENST00000230990.7
heparin binding EGF like growth factor
chr12_-_86838867 0.85 ENST00000621808.4
MGAT4 family member C
chr2_-_68871382 0.80 ENST00000295379.2
bone morphogenetic protein 10
chr12_+_15546344 0.73 ENST00000674388.1
ENST00000542557.5
ENST00000445537.6
ENST00000544244.5
ENST00000442921.7
protein tyrosine phosphatase receptor type O
chr12_-_89352395 0.71 ENST00000308385.6
dual specificity phosphatase 6
chr12_-_89352487 0.69 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr14_+_94026314 0.68 ENST00000203664.10
ENST00000553723.1
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr3_+_159839847 0.67 ENST00000445224.6
schwannomin interacting protein 1
chr1_-_208244375 0.59 ENST00000367033.4
plexin A2
chr14_+_32329341 0.57 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr6_+_63521738 0.56 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr8_+_22567038 0.51 ENST00000523348.1
sorbin and SH3 domain containing 3
chr6_-_87095059 0.48 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr8_-_10655137 0.46 ENST00000382483.4
RP1 like 1
chr12_-_16606102 0.46 ENST00000537304.6
LIM domain only 3
chr1_-_153150884 0.44 ENST00000368748.5
small proline rich protein 2G
chr12_-_16605939 0.44 ENST00000541295.5
ENST00000535535.5
LIM domain only 3
chr17_-_19387170 0.44 ENST00000395592.6
ENST00000299610.5
microfibril associated protein 4
chr14_+_32329256 0.43 ENST00000280979.9
A-kinase anchoring protein 6
chr17_-_19386785 0.43 ENST00000497081.6
microfibril associated protein 4
chr21_-_30492008 0.38 ENST00000334063.6
keratin associated protein 19-3
chr11_+_31650024 0.38 ENST00000638317.1
elongator acetyltransferase complex subunit 4
chr10_+_119207560 0.37 ENST00000392870.3
G protein-coupled receptor kinase 5
chr1_-_193059296 0.36 ENST00000367450.7
ENST00000367451.8
ENST00000367454.6
ENST00000367448.5
ENST00000367449.5
ubiquitin C-terminal hydrolase L5
chr5_-_157059109 0.34 ENST00000523175.6
ENST00000522693.5
hepatitis A virus cellular receptor 1
chr14_-_68794597 0.34 ENST00000336440.3
ZFP36 ring finger protein like 1
chr3_+_189789734 0.34 ENST00000437221.5
ENST00000392463.6
ENST00000392461.7
ENST00000449992.5
ENST00000456148.1
tumor protein p63
chr6_+_130018565 0.33 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr6_+_25754699 0.33 ENST00000439485.6
ENST00000377905.9
solute carrier family 17 member 4
chr1_-_193059489 0.32 ENST00000367455.8
ENST00000421683.1
ubiquitin C-terminal hydrolase L5
chrX_+_43656289 0.31 ENST00000338702.4
monoamine oxidase A
chr2_+_28395511 0.30 ENST00000436647.1
FOS like 2, AP-1 transcription factor subunit
chr14_+_39114289 0.29 ENST00000396249.7
ENST00000250379.13
ENST00000534684.7
ENST00000308317.12
ENST00000527381.2
gem nuclear organelle associated protein 2
chr2_-_70553440 0.27 ENST00000450929.5
transforming growth factor alpha
chr21_-_31160904 0.26 ENST00000636887.1
TIAM Rac1 associated GEF 1
chr11_-_5343524 0.26 ENST00000300773.3
olfactory receptor family 51 subfamily B member 5
chr3_+_111999189 0.26 ENST00000455401.6
transgelin 3
chr4_-_22443110 0.26 ENST00000508133.5
adhesion G protein-coupled receptor A3
chr3_+_111998739 0.25 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr3_+_111998915 0.25 ENST00000478951.6
transgelin 3
chr7_-_80512041 0.25 ENST00000398291.4
G protein subunit alpha transducin 3
chr13_+_97960192 0.25 ENST00000496368.6
ENST00000421861.7
ENST00000357602.7
importin 5
chr3_-_71360753 0.24 ENST00000648783.1
forkhead box P1
chr3_-_101320558 0.24 ENST00000193391.8
interphotoreceptor matrix proteoglycan 2
chr3_+_189789643 0.23 ENST00000354600.10
tumor protein p63
chrX_+_23908006 0.22 ENST00000379211.8
ENST00000648352.1
chromosome X open reading frame 58
chr6_-_32190170 0.21 ENST00000375050.6
PBX homeobox 2
chr17_-_41397600 0.21 ENST00000251645.3
keratin 31
chr5_-_141618914 0.21 ENST00000518047.5
diaphanous related formin 1
chr20_+_57561103 0.21 ENST00000319441.6
phosphoenolpyruvate carboxykinase 1
chr21_-_14658812 0.21 ENST00000647101.1
SAM domain, SH3 domain and nuclear localization signals 1
chr11_-_31509569 0.21 ENST00000526776.5
inner mitochondrial membrane peptidase subunit 1
chr5_+_172641241 0.20 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
neuralized E3 ubiquitin protein ligase 1B
chr4_+_56907876 0.20 ENST00000640168.2
ENST00000309042.12
RE1 silencing transcription factor
chr5_-_141619049 0.20 ENST00000647433.1
ENST00000253811.10
ENST00000389057.9
ENST00000398557.8
diaphanous related formin 1
chr5_-_141618957 0.19 ENST00000389054.8
diaphanous related formin 1
chr4_-_73620629 0.19 ENST00000342081.7
Ras association domain family member 6
chr11_-_31509588 0.19 ENST00000534812.5
ENST00000529749.5
ENST00000532287.6
ENST00000278200.5
ENST00000530023.5
ENST00000533642.1
inner mitochondrial membrane peptidase subunit 1
chr4_-_73620391 0.18 ENST00000395777.6
ENST00000307439.10
Ras association domain family member 6
chr3_+_141387616 0.18 ENST00000509883.5
zinc finger and BTB domain containing 38
chrX_+_108044967 0.17 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr7_-_13988863 0.17 ENST00000405358.8
ETS variant transcription factor 1
chr4_-_163473732 0.17 ENST00000280605.5
transketolase like 2
chr12_-_16608183 0.17 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr12_-_16608073 0.16 ENST00000441439.6
LIM domain only 3
chr7_-_13989658 0.16 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETS variant transcription factor 1
chrX_+_108045050 0.16 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr15_+_92900338 0.16 ENST00000625990.3
chromodomain helicase DNA binding protein 2
chr5_+_135579193 0.16 ENST00000646290.1
solute carrier family 25 member 48
chr12_+_53954870 0.16 ENST00000243103.4
homeobox C12
chr3_-_51875597 0.15 ENST00000446461.2
IQ motif containing F5
chr22_-_28306645 0.15 ENST00000612946.4
tetratricopeptide repeat domain 28
chr11_-_72112068 0.15 ENST00000537644.5
ENST00000538919.5
ENST00000539395.1
ENST00000542531.5
anaphase promoting complex subunit 15
chr2_-_157444044 0.15 ENST00000264192.8
cytohesin 1 interacting protein
chrX_-_155071064 0.15 ENST00000369484.8
ENST00000369476.8
C-X9-C motif containing 4
mature T cell proliferation 1
chr17_-_41315706 0.14 ENST00000334202.5
keratin associated protein 17-1
chr6_+_29306626 0.14 ENST00000377160.4
olfactory receptor family 14 subfamily J member 1
chr11_-_72112750 0.14 ENST00000545680.5
ENST00000543587.5
ENST00000538393.5
ENST00000535234.5
ENST00000227618.8
ENST00000535503.5
anaphase promoting complex subunit 15
chr11_-_72112669 0.14 ENST00000545944.5
ENST00000502597.2
anaphase promoting complex subunit 15
chr6_-_89217339 0.14 ENST00000454853.7
gamma-aminobutyric acid type A receptor subunit rho1
chr17_-_41424583 0.14 ENST00000225550.4
keratin 37
chr4_+_109827963 0.13 ENST00000317735.7
retinal pigment epithelium-derived rhodopsin homolog
chr21_-_40847149 0.13 ENST00000400454.6
DS cell adhesion molecule
chrX_+_69616067 0.13 ENST00000338901.4
ENST00000525810.5
ENST00000527388.5
ENST00000374553.6
ENST00000374552.9
ENST00000524573.5
ectodysplasin A
chr3_-_127822455 0.12 ENST00000265052.10
monoglyceride lipase
chr8_+_26293112 0.12 ENST00000523925.5
ENST00000315985.7
protein phosphatase 2 regulatory subunit Balpha
chr10_-_92497727 0.12 ENST00000496903.5
ENST00000678824.1
ENST00000371581.9
insulin degrading enzyme
chr13_+_57631735 0.11 ENST00000377918.8
protocadherin 17
chr6_+_121437378 0.11 ENST00000650427.1
ENST00000647564.1
gap junction protein alpha 1
chr3_+_111999326 0.10 ENST00000494932.1
transgelin 3
chr4_+_112860912 0.10 ENST00000671951.1
ankyrin 2
chr7_+_116222804 0.10 ENST00000393481.6
testin LIM domain protein
chr15_+_92900189 0.10 ENST00000626874.2
ENST00000627622.1
ENST00000629346.2
ENST00000628375.2
ENST00000420239.7
ENST00000394196.9
chromodomain helicase DNA binding protein 2
chr1_+_50106265 0.10 ENST00000357083.8
ELAV like RNA binding protein 4
chr12_-_52652207 0.10 ENST00000309680.4
keratin 2
chrX_-_23907887 0.10 ENST00000379226.9
apolipoprotein O
chr4_+_112861053 0.10 ENST00000672221.1
ankyrin 2
chr15_+_58410543 0.09 ENST00000356113.10
ENST00000414170.7
lipase C, hepatic type
chr4_+_112860981 0.09 ENST00000671704.1
ankyrin 2
chr6_-_155314444 0.09 ENST00000367166.5
transcription factor B1, mitochondrial
chr10_+_35195843 0.09 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr11_-_36598221 0.09 ENST00000311485.8
ENST00000527033.5
ENST00000532616.1
ENST00000618712.4
recombination activating 2
chr17_-_42185452 0.09 ENST00000293330.1
hypocretin neuropeptide precursor
chr12_-_52553139 0.08 ENST00000267119.6
keratin 71
chr2_-_2326378 0.08 ENST00000647618.1
myelin transcription factor 1 like
chr18_+_63702958 0.08 ENST00000544088.6
serpin family B member 11
chr1_+_175067831 0.08 ENST00000239462.9
tenascin N
chr13_-_44161257 0.08 ENST00000400419.2
small integral membrane protein 2
chr7_+_148590760 0.07 ENST00000307003.3
chromosome 7 open reading frame 33
chr13_-_103066411 0.07 ENST00000245312.5
solute carrier family 10 member 2
chr9_+_106863121 0.07 ENST00000472574.1
ENST00000277225.10
zinc finger protein 462
chr15_+_74788542 0.07 ENST00000567571.5
C-terminal Src kinase
chr4_+_40196907 0.07 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chrX_+_30235894 0.07 ENST00000620842.1
MAGE family member B3
chr18_-_13915531 0.06 ENST00000327606.4
melanocortin 2 receptor
chr8_+_76681208 0.06 ENST00000651372.2
zinc finger homeobox 4
chr19_-_7633713 0.06 ENST00000311069.6
Purkinje cell protein 2
chr9_-_114806031 0.06 ENST00000374045.5
TNF superfamily member 15
chr6_+_158017048 0.06 ENST00000638626.1
synaptojanin 2
chr19_+_9178979 0.06 ENST00000642043.1
ENST00000641288.2
olfactory receptor family 7 subfamily D member 2
chrX_-_21658324 0.06 ENST00000379499.3
kelch like family member 34
chr4_+_40197023 0.06 ENST00000381799.10
ras homolog family member H
chr13_+_45464901 0.06 ENST00000349995.10
component of oligomeric golgi complex 3
chr11_+_107591077 0.05 ENST00000531234.5
ENST00000265840.12
ELMO domain containing 1
chr1_+_50105666 0.05 ENST00000651347.1
ELAV like RNA binding protein 4
chr16_-_18926408 0.05 ENST00000446231.7
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr3_-_57165332 0.05 ENST00000296318.12
interleukin 17 receptor D
chr10_-_101229449 0.05 ENST00000370193.4
ladybird homeobox 1
chr21_-_34526815 0.05 ENST00000492600.1
regulator of calcineurin 1
chr12_+_120694167 0.04 ENST00000535656.1
malectin
chr3_+_77039836 0.04 ENST00000461745.5
roundabout guidance receptor 2
chr2_-_2324323 0.04 ENST00000648339.1
ENST00000647694.1
myelin transcription factor 1 like
chr7_-_19145306 0.04 ENST00000275461.3
Fer3 like bHLH transcription factor
chr10_+_18260715 0.04 ENST00000615785.4
ENST00000617363.4
ENST00000396576.6
calcium voltage-gated channel auxiliary subunit beta 2
chr21_-_30881572 0.04 ENST00000332378.6
keratin associated protein 11-1
chr20_-_51802433 0.04 ENST00000395997.3
spalt like transcription factor 4
chr19_+_38374557 0.04 ENST00000215071.9
proteasome 26S subunit, non-ATPase 8
chr19_+_38374549 0.03 ENST00000620216.4
proteasome 26S subunit, non-ATPase 8
chr4_+_87650277 0.03 ENST00000339673.11
ENST00000282479.8
dentin matrix acidic phosphoprotein 1
chr1_+_45913647 0.03 ENST00000674079.1
microtubule associated serine/threonine kinase 2
chr10_+_112950586 0.03 ENST00000355717.9
ENST00000352065.10
ENST00000369395.6
ENST00000545257.6
transcription factor 7 like 2
chrX_-_18672101 0.03 ENST00000379984.4
retinoschisin 1
chr19_-_7632971 0.03 ENST00000598935.5
Purkinje cell protein 2
chr9_-_34729482 0.03 ENST00000378788.4
family with sequence similarity 205 member A
chr19_-_49423441 0.03 ENST00000270631.2
parathyroid hormone 2
chr2_+_162318884 0.03 ENST00000446271.5
ENST00000429691.6
grancalcin
chr1_-_47190013 0.03 ENST00000294338.7
PDZK1 interacting protein 1
chr17_+_39628496 0.02 ENST00000394265.5
ENST00000394267.2
protein phosphatase 1 regulatory inhibitor subunit 1B
chr1_-_182671853 0.02 ENST00000367556.5
regulator of G protein signaling 8
chr5_+_127649018 0.02 ENST00000379445.7
cortexin 3
chr1_-_21279520 0.02 ENST00000357071.8
endothelin converting enzyme 1
chr1_-_158426237 0.02 ENST00000641042.1
olfactory receptor family 10 subfamily K member 2
chr3_+_141386862 0.02 ENST00000513258.5
zinc finger and BTB domain containing 38
chr10_+_112950240 0.01 ENST00000627217.3
ENST00000534894.5
ENST00000538897.5
ENST00000536810.5
ENST00000355995.8
ENST00000542695.5
ENST00000543371.5
transcription factor 7 like 2
chr1_-_182671902 0.01 ENST00000483095.6
regulator of G protein signaling 8
chr7_-_126533850 0.01 ENST00000444921.3
glutamate metabotropic receptor 8
chr17_+_7407838 0.01 ENST00000302926.7
neuroligin 2
chr20_+_43558968 0.00 ENST00000647834.1
ENST00000373100.7
ENST00000648083.1
ENST00000648530.1
serum/glucocorticoid regulated kinase 2
chr8_-_42501224 0.00 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr6_+_50818857 0.00 ENST00000393655.4
transcription factor AP-2 beta
chr10_+_112950452 0.00 ENST00000369397.8
transcription factor 7 like 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.7 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 3.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.2 1.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 1.0 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.5 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.8 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.3 GO:1904582 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.1 0.9 GO:0051541 elastin metabolic process(GO:0051541)
0.1 1.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.1 0.2 GO:2000797 amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
0.1 0.3 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.6 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.9 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.2 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.7 GO:0021670 lateral ventricle development(GO:0021670)
0.0 1.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.4 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.9 GO:0071953 elastic fiber(GO:0071953)
0.1 1.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.9 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 1.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 2.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.2 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 3.0 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 0.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.8 GO:0031433 telethonin binding(GO:0031433)
0.1 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0004802 transketolase activity(GO:0004802)
0.0 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.7 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.7 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.9 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME OPSINS Genes involved in Opsins